FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Brian Harding

Research Profile

Concepts & Ideas

Disorders

Physiology

Chemicals & Drugs

Living Beings

Mouse

Procedures

Genes & Molecular Sequences

Amino Acid Sequences

Anatomy

Chromosomes, Human, Pair 11

Co-author Network

Publications

TOP 3
Gerard V Walls; Brian Harding; Nathan R Hill; Mahsa Javid; Jeshmi Jeyabalan; Anita A C Reed; Rajesh V Thakker
Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors.
Gerard V Walls; Damian J Tyler; Olaf Ansorge; Miriam Bazan-Peregrino; Paul T Christie; Kieran Clarke; Brian Harding; Mahsa Javid; Jeshmi Jeyabalan; Manuel C Lemos; Sian Piret; Anita A C Reed; Len Seymour; Daniel J Stuckey; Rajesh V Thakker
MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.
Fadil M Hannan; Brian Harding; Heike Jung; Manuel C Lemos; Eileen Marks; David McCredie; Zulf Mughal; M Andrew Nesbit; Christine Rodda; Nigel Rust; Roger Bouillon; Michael R Bowl; Caroline Brain; Nicola Bridges; Edward M Brown; Christine Burren; Paul T Christie; John M Connell; Treena Cranston; Alan J Curley; Carl Fratter; Sherida Tollefsen; Jeremy J O Turner; Jenny J Yang; Chen Zhang; Rajesh V Thakker
Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Brian Harding (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Gerard V Walls; Brian Harding; Nathan R Hill; Mahsa Javid; Jeshmi Jeyabalan; Anita A C Reed; Rajesh V Thakker
Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors.
Endocrinology 2012;153(11):5167-79.
2012: Gerard V Walls; Damian J Tyler; Olaf Ansorge; Miriam Bazan-Peregrino; Paul T Christie; Kieran Clarke; Brian Harding; Mahsa Javid; Jeshmi Jeyabalan; Manuel C Lemos; Sian Piret; Anita A C Reed; Len Seymour; Daniel J Stuckey; Rajesh V Thakker
MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.
Cancer research 2012;72(19):5060-8.
2012: Fadil M Hannan; Brian Harding; Heike Jung; Manuel C Lemos; Eileen Marks; David McCredie; Zulf Mughal; M Andrew Nesbit; Christine Rodda; Nigel Rust; Roger Bouillon; Michael R Bowl; Caroline Brain; Nicola Bridges; Edward M Brown; Christine Burren; Paul T Christie; John M Connell; Treena Cranston; Alan J Curley; Carl Fratter; Sherida Tollefsen; Jeremy J O Turner; Jenny J Yang; Chen Zhang; Rajesh V Thakker
Identification of 70 calcium-sensing receptor mutations in hyper- and hypo-calcaemic patients: evidence for clustering of extracellular domain mutations at calcium-binding sites.
Human molecular genetics 2012;21(12):2768-78.
2009: Brian Harding; Manuel C Lemos; Anita A C Reed; Gerard V Walls; Jeshmi Jeyabalan; Michael R Bowl; Hilda Tateossian; Nicky Sullivan; Tertius Hough; William D Fraser; Olaf Ansorge; Michael T Cheeseman; Rajesh V Thakker
Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.
Endocrine-related cancer 2009;16(4):1313-27.
2009: Manuel C Lemos; Brian Harding; Anita A C Reed; Jeshmi Jeyabalan; Gerard V Walls; Michael R Bowl; James Sharpe; Sarah Wedden; Julie E Moss; Allyson Ross; Duncan Davidson; Rajesh V Thakker
Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers.
The Journal of endocrinology 2009;203(1):133-42.
2007: Manuel C Lemos; Brian Harding; Stephen M Shalet; Rajesh V Thakker
A novel MEN1 intronic mutation associated with multiple endocrine neoplasia type 1.
Clinical endocrinology 2007;66(5):709-13.
2007: Asif Ali; Paul T Christie; Irina V Grigorieva; Brian Harding; Hilde Van Esch; S Faisal Ahmed; Maria Bitner-Glindzicz; Eberhard Blind; Catherine Bloch; Patricia Christin; Peter Clayton; Jozef Gecz; Brigitte Gilbert-Dussardier; Encarna Guillen-Navarro; Anna Hackett; Isil Halac; Geoffrey N Hendy; Fiona Lalloo; Christoph J Mache; Zulf Mughal; Albert C M Ong; Choni Rinat; Nicholas Shaw; Sarah F Smithson; John Tolmie; Jacques Weill; M Andrew Nesbit; Rajesh V Thakker
Functional characterization of GATA3 mutations causing the hypoparathyroidism-deafness-renal (HDR) dysplasia syndrome: insight into mechanisms of DNA binding by the GATA3 transcription factor.
Human molecular genetics 2007;16(3):265-75.
2006: Brian Harding; Alan J Curley; Fadil M Hannan; Paul T Christie; Michael R Bowl; Jeremy J O Turner; Mathew Barber; Irina Gillham-Nasenya; Geeta Hampson; Tim D Spector; Rajesh V Thakker
Functional characterization of calcium sensing receptor polymorphisms and absence of association with indices of calcium homeostasis and bone mineral density.
Clinical endocrinology 2006;65(5):598-605.
2006: Karin J Bradley; Branca Maria Cavaco; Michael R Bowl; Brian Harding; T Cranston; Carl Fratter; G M Besser; M Conceição Pereira; M W J Davie; Nicholas E Dudley; Valeriano Leite; G P Sadler; A Seller; Rajesh V Thakker
Parafibromin mutations in hereditary hyperparathyroidism syndromes and parathyroid tumours.
Clinical endocrinology 2006;64(3):299-306.
2005: Ann M Kennedy; Masaki Inada; Stephen M Krane; Paul T Christie; Brian Harding; Carlos López-Otín; Luis M Sánchez; Anna A J Pannett; Andrew Dearlove; Claire Hartley; Michael H Byrne; Anita A C Reed; M Andrew Nesbit; Michael P Whyte; Rajesh V Thakker
MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMD(MO).
The Journal of clinical investigation 2005;115(10):2832-42.
2005: Michael R Bowl; M Andrew Nesbit; Brian Harding; Elaine Levy; Andrew Jefferson; Emanuela Volpi; Karine Rizzoti; Robin Lovell-Badge; David Schlessinger; Michael P Whyte; Rajesh V Thakker
An interstitial deletion-insertion involving chromosomes 2p25.3 and Xq27.1, near SOX3, causes X-linked recessive hypoparathyroidism.
The Journal of clinical investigation 2005;115(10):2822-31.
2005: Manuel C Lemos; Peter Kotanko; Paul T Christie; Brian Harding; Theodora Javor; Christine Smith; Ana Munoz; Rajesh V Thakker
A novel EXT1 splice site mutation in a kindred with hereditary multiple exostosis and osteoporosis.
The Journal of clinical endocrinology and metabolism 2005;90(9):5386-92.
2005: Karin J Bradley; Branca Maria Cavaco; Michael R Bowl; Brian Harding; A Young; Rajesh V Thakker
Utilisation of a cryptic non-canonical donor splice site of the gene encoding PARAFIBROMIN is associated with familial isolated primary hyperparathyroidism.
Journal of medical genetics 2005;42(8):e51.
2004: M Andrew Nesbit; Michael R Bowl; Brian Harding; David Schlessinger; Michael P Whyte; Rajesh V Thakker
X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase.
Genomics 2004;84(6):1060-70.
2004: M Andrew Nesbit; Michael R Bowl; Brian Harding; Asif Ali; Alejandro Ayala; Carol Crowe; Angus Dobbie; Geeta Hampson; Ian Holdaway; Michael A. Levine; Robert McWilliams; Susan Rigden; Julian Sampson; Andrew J Williams; Rajesh V Thakker
Characterization of GATA3 mutations in the hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome.
The Journal of biological chemistry 2004;279(21):22624-34.
2004: Branca Maria Cavaco; Laura Guerra; Karin J Bradley; Davide MC Carvalho; Brian Harding; Amélia Oliveira; Maria-Amparo Santos; Luís G Sobrinho; Rajesh V Thakker; Valeriano Leite
Hyperparathyroidism-jaw tumor syndrome in Roma families from Portugal is due to a founder mutation of the HRPT2 gene.
The Journal of clinical endocrinology and metabolism 2004;89(4):1747-52.
2003: Anna A J Pannett; Ann M Kennedy; Jeremy J O Turner; Simon A Forbes; Branca Maria Cavaco; J H Duncan Bassett; L Cianferotti; Brian Harding; B Shine; F Flinter; C G H Maidment; Richard C Trembath; Rajesh V Thakker
Multiple endocrine neoplasia type 1 (MEN1) germline mutations in familial isolated primary hyperparathyroidism.
Clinical endocrinology 2003;58(5):639-46.
2003: Jeremy J O Turner; J M Stacey; Brian Harding; Peter Kotanko; Karl Lhotta; Juan G Puig; I Roberts; Rosa J Torres; Rajesh V Thakker
UROMODULIN mutations cause familial juvenile hyperuricemic nephropathy.
The Journal of clinical endocrinology and metabolism 2003;88(3):1398-401.
2003: Joanna M Stacey; Jeremy J O Turner; Brian Harding; M Andrew Nesbit; Peter Kotanko; Karl Lhotta; Juan G Puig; Rosa J Torres; Rajesh V Thakker
Genetic mapping studies of familial juvenile hyperuricemic nephropathy on chromosome 16p11-p13.
The Journal of clinical endocrinology and metabolism 2003;88(1):464-70.
2002: Jeremy J O Turner; Poloko D Leotlela; Anna A J Pannett; Simon A Forbes; J H Duncan Bassett; Brian Harding; Paul T Christie; David Bowen-Jones; Sian Ellard; Andrew T Hattersley; Charles E Jackson; Richard Pope; Oliver W Quarrell; Richard C Trembath; Rajesh V Thakker
Frequent occurrence of an intron 4 mutation in multiple endocrine neoplasia type 1.
The Journal of clinical endocrinology and metabolism 2002;87(6):2688-93.
2001: Paul T Christie; Brian Harding; M Andrew Nesbit; Michael P Whyte; Rajesh V Thakker
X-linked hypophosphatemia attributable to pseudoexons of the PHEX gene.
The Journal of clinical endocrinology and metabolism 2001;86(8):3840-4.
2000: Steven Mumm; Paul T Christie; Patrick M Finnegan; Jonathan Jones; Peter DIxon; Anna A J Pannett; Brian Harding; Gary S Gottesman; Rajesh V Thakker; Michael P Whyte
A five-base pair deletion in the sedlin gene causes spondyloepiphyseal dysplasia tarda in a six-generation Arkansas kindred.
The Journal of clinical endocrinology and metabolism 2000;85(9):3343-7.
2000: Hilde Van Esch; Peter Groenen; M Andrew Nesbit; S Schuffenhauer; Peter Lichtner; G Vanderlinden; Brian Harding; R Beetz; R W Bilous; I Holdaway; N J Shaw; Jean-Pierre Fryns; Wim Van de Ven; Rajesh V Thakker; koenraad devriendt
GATA3 haplo-insufficiency causes human HDR syndrome.
Nature 2000;406(6794):419-22.
1999: C Williamson; Branca Maria Cavaco; A Jauch; Peter DIxon; S Forbes; Brian Harding; Heidi Holtgreve-Grez; Brigitte Schoell; M C Pereira; A P Font; M M Loureiro; Luís G Sobrinho; Maria-Amparo Santos; Rajesh V Thakker; A Jausch
Mapping the gene causing hereditary primary hyperparathyroidism in a Portuguese kindred to chromosome 1q22-q31.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(2):230-9.
1999: J H Duncan Bassett; P Rashbass; Brian Harding; Simon A Forbes; Anna A J Pannett; Rajesh V Thakker
Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, men1.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(1):3-10.
1998: J H Duncan Bassett; Simon A Forbes; Anna A J Pannett; SE Lloyd; Paul T Christie; C Wooding; Brian Harding; G M Besser; C R Edwards; J P Monson; J Sampson; J A Wass; M H Wheeler; Rajesh V Thakker
Characterization of mutations in patients with multiple endocrine neoplasia type 1.
American journal of human genetics 1998;62(2):232-44.
1997: Simon A Forbes; Anna A J Pannett; J H Duncan Bassett; Brian Harding; C Wooding; Rajesh V Thakker; R Butler; D Ogilvie; R Anand; Patrick Gaudray; Günther Weber; Catharina Larsson; Chang X Zhang; Alain Calender; Jo W M Höppener; Cornelis J M Lips; Koen Kas
Mapping of the gene encoding the B56 beta subunit of protein phosphatase 2A (PPP2R5B) to a 0.5-Mb region of chromosome 11q13 and its exclusion as a candidate gene for multiple endocrine neoplasia type 1 (MEN1).
Human genetics 1997;100(3-4):481-5.
1996: M A Pook; R Thakrar; B Pottinger; Brian Harding; D Porteous; Veronica van Heyningen; John Kenneth Cowell; C Jones; S Povey; Kay E Davies; Rajesh V Thakker
EagI and NotI linking clones from human chromosomes 11 and Xp.
Human genetics 1996;97(6):742-9.
1996: J T Pang; SE Lloyd; C Wooding; B Farren; B Pottinger; Brian Harding; S E Leigh; M A Pook; F J Benham; G T Gillett; R T Taggart; Rajesh V Thakker
Genetic mapping studies of 40 loci and 23 cosmids in chromosome 11p13-11q13, and exclusion of mu-calpain as the multiple endocrine neoplasia type 1 gene.
Human genetics 1996;97(6):732-41.
1996: SE Lloyd; SH Pearce; Simon E Fisher; Klaus Steinmeyer; B Schwappach; Steven J Scheinman; Brian Harding; Alessandra Bolino; M Devoto; Paul Goodyer; S P Rigden; Oliver Wrong; Thomas J Jentsch; IW Craig; Rajesh V Thakker
A common molecular basis for three inherited kidney stone diseases.
Nature 1996;379(6564):445-9.