Emanuela Arvat

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Anorexia Nervosa

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Giordano R; Picu A; Bonelli L; Balbo M; Berardelli R; Marinazzo E; Corneli G; Ghigo E; Arvat E
Hypothalamus-pituitary-adrenal axis evaluation in patients with hypothalamo-pituitary disorders: comparison of different provocative tests.
Broglio Fabio; Grottoli Silvia; Arvat Emanuela; Ghigo Ezio
Endocrine actions of cortistatin: in vivo studies.
Giordano Roberta; Bonelli Lorenza; Marinazzo Elisa; Ghigo Ezio; Arvat Emanuela
Growth hormone treatment in human ageing: benefits and risks.

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All Publications

2008: Giordano R; Picu A; Bonelli L; Balbo M; Berardelli R; Marinazzo E; Corneli G; Ghigo E; Arvat E
Hypothalamus-pituitary-adrenal axis evaluation in patients with hypothalamo-pituitary disorders: comparison of different provocative tests.
Clinical endocrinology 2008;68(6):935-41.
2008: Broglio Fabio; Grottoli Silvia; Arvat Emanuela; Ghigo Ezio
Endocrine actions of cortistatin: in vivo studies.
Molecular and cellular endocrinology 2008;286(1-2):123-7.
2008: Giordano Roberta; Bonelli Lorenza; Marinazzo Elisa; Ghigo Ezio; Arvat Emanuela
Growth hormone treatment in human ageing: benefits and risks.
Hormones (Athens, Greece) 2008;7(2):133-9.
2007: Giordano R; Picu A; Bonelli L; Broglio F; Prodam F; Grottoli S; Muccioli G; Ghigo E; Arvat E
The activation of somatostatinergic receptors by either somatostatin-14 or cortistatin-17 often inhibits ACTH hypersecretion in patients with Cushing's disease.
European journal of endocrinology / European Federation of Endocrine Societies 2007;157(4):393-8.
2007: Giordano R; Pellegrino M; Picu A; Bonelli L; Oleandri S E; Pellissetto C; Limone P; Migliaretti G; Maccario M; Ghigo E; Arvat E
Primary hyperaldosteronism is associated with derangement in the regulation of the hypothalamus-pituitary-adrenal axis in humans.
Journal of endocrinological investigation 2007;30(7):558-63.
2007: Terzolo Massimo; Angeli Alberto; Fassnacht Martin; Daffara Fulvia; Tauchmanova Libuse; Conton Pier Antonio; Rossetto Ruth; Buci Lisa; Sperone Paola; Grossrubatscher Erika; Reimondo Giuseppe; Bollito Enrico; Papotti Mauro; Saeger Wolfgang; Hahner Stefanie; Koschker Ann-Cathrin; Arvat Emanuela; Ambrosi Bruno; Loli Paola; Lombardi Gaetano; Mannelli Massimo; Bruzzi Paolo; Mantero Franco; Allolio Bruno; Dogliotti Luigi; Berruti Alfredo
Adjuvant mitotane treatment for adrenocortical carcinoma.
The New England journal of medicine 2007;356(23):2372-80.
2007: Tassone F; Broglio F; Gianotti L; Arvat E; Ghigo E; Maccario M
Ghrelin and other gastrointestinal peptides involved in the control of food intake.
Mini reviews in medicinal chemistry 2007;7(1):47-53.
2006: Mondelli Valeria; Gianotti Laura; Picu Andreea; Abbate Daga Giovanni; Giordano Roberta; Berardelli Rita; Pariante Carmine M; Fassino Secondo; Ghigo Ezio; Arvat Emanuela
Neuroendocrine effects of citalopram infusion in anorexia nervosa.
Psychoneuroendocrinology 2006;31(10):1139-48.
2006: Bo Mario; Massaia Massimiliano; Zannella Patrizia; Cappa Giorgetta; Ferrario Ermanno; Rainero Innocenzo; Arvat Emanuela; Giordano Roberta; Molaschi Mario
Dehydroepiandrosterone sulfate (DHEA-S) and Alzheimer's dementia in older subjects.
International journal of geriatric psychiatry 2006;21(11):1065-70.
2006: Giordano Roberta; Balbo Marcella; Picu Andreea; Bonelli Lorenza; Berardelli Rita; Falorni Alberto; Ghigo Ezio; Arvat Emanuela
Corticotrope hypersecretion coupled with cortisol hypo-responsiveness to stimuli is present in patients with autoimmune endocrine diseases: evidence for subclinical primary hypoadrenalism?
European journal of endocrinology / European Federation of Endocrine Societies 2006;155(3):421-8.
2006: Lanfranco Fabio; Gianotti Laura; Picu Andreea; Giordano Roberta; Daga Giovanni Abbate; Mondelli Valeria; Malfi Giuseppe; Fassino Secondo; Ghigo Ezio; Arvat Emanuela
Effects of free fatty acids on ACTH and cortisol secretion in anorexia nervosa.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(5):731-8.
2006: Rainero Innocenzo; Ferrero Margherita; Rubino Elisa; Valfrè Walter; Pellegrino Michela; Arvat Emanuela; Giordano Roberta; Ghigo Ezio; Limone Paolo; Pinessi Lorenzo
Endocrine function is altered in chronic migraine patients with medication-overuse.
Headache 2006;46(4):597-603.
2006: Pecori Giraldi Francesca; Scaroni Carla; Arvat Emanuela; Martin Martina; Giordano Roberta; Albiger Nora; Leao Adriana A S; Picu Andreea; Mantero Franco; Cavagnini Francesco
Effect of protracted treatment with rosiglitazone, a PPARgamma agonist, in patients with Cushing's disease.
Clinical endocrinology 2006;64(2):219-24.
2006: Giordano Roberta; Pellegrino Micaela; Picu Andreea; Bonelli Lorenza; Balbo Marcella; Berardelli Rita; Lanfranco Fabio; Ghigo Ezio; Arvat Emanuela
Neuroregulation of the hypothalamus-pituitary-adrenal (HPA) axis in humans: effects of GABA-, mineralocorticoid-, and GH-Secretagogue-receptor modulation.
TheScientificWorldJournal 2006;6():1-11.
2005: Giordano Roberta; Aimaretti Gianluca; Lanfranco Fabio; Bo Mario; Baldi Matteo; Broglio Fabio; Baldelli Roberto; Grottoli Silvia; Ghigo Ezio; Arvat Emanuela
Testing pituitary function in aging individuals.
Endocrinology and metabolism clinics of North America 2005;34(4):895-906, viii-ix.
2005: Giordano Roberta; Picu Andrea; Pagotto Uberto; De Iasio Rosaria; Bonelli Lorenza; Prodam Flavia; Broglio Fabio; Marafetti Lisa; Pasquali Renato; Maccario Mauro; Ghigo Ezio; Arvat Emanuela
The negative association between total ghrelin levels, body mass and insulin secretion is lost in hypercortisolemic patients with Cushing's disease.
European journal of endocrinology / European Federation of Endocrine Societies 2005;153(4):535-43.
2005: Giordano Roberta; Bo Mario; Pellegrino Micaela; Vezzari Marco; Baldi Matteo; Picu Andreea; Balbo Marcella; Bonelli Lorenza; Migliaretti Giuseppe; Ghigo Ezio; Arvat Emanuela
Hypothalamus-pituitary-adrenal hyperactivity in human aging is partially refractory to stimulation by mineralocorticoid receptor blockade.
The Journal of clinical endocrinology and metabolism 2005;90(10):5656-62.
2005: Fassino S; Daga G Abbate; Mondelli V; Pierò A; Broglio F; Picu A; Giordano R; Baldi M; Arvat E; Ghigo E; Gianotti L
Hormonal and metabolic responses to acute ghrelin administration in patients with bulimia nervosa.
Psychoneuroendocrinology 2005;30(6):534-40.
2005: Ghigo E; Broglio F; Arvat E; Maccario M; Papotti M; Muccioli G
Ghrelin: more than a natural GH secretagogue and/or an orexigenic factor.
Clinical endocrinology 2005;62(1):1-17.
2005: Giordano R; Lanfranco F; Bo M; Pellegrino M; Picu A; Baldi M; Balbo M; Bonelli L; Grottoli S; Ghigo E; Arvat E
Somatopause reflects age-related changes in the neural control of GH/IGF-I axis.
Journal of endocrinological investigation 2005;28(3 Suppl):94-8.
2004: Aimaretti Gianluca; Baldelli Roberto; Corneli Ginevra; Bellone Simonetta; Rovere Silvia; Croce Chiara; Ragazzoni Federico; Giordano Roberta; Arvat Emanuela; Bona Gianni; Ghigo Ezio
GHRH and GH secretagogues: clinical perspectives and safety.
Pediatric endocrinology reviews : PER 2004;2 Suppl 1():86-92.
2004: Gottero C; Broglio F; Prodam F; Destefanis S; Bellone S; Benso A; Gauna C; Arvat E; van der Lely A J; Ghigo E
Ghrelin: a link between eating disorders, obesity and reproduction.
Nutritional neuroscience 2004;7(5-6):255-70.
2004: Broglio Fabio; Gottero Cristina; Prodam Flavia; Destefanis Silvia; Gauna Carlotta; Me Elisa; Riganti Fabrizio; Vivenza Daniela; Rapa Anna; Martina Valentino; Arvat Emanuela; Bona Gianni; van der Lely Aart Jan; Ghigo Ezio
Ghrelin secretion is inhibited by glucose load and insulin-induced hypoglycaemia but unaffected by glucagon and arginine in humans.
Clinical endocrinology 2004;61(4):503-9.
2004: Broglio Fabio; Prodam Flavia; Gottero Cristina; Destefanis Silvia; Me Elisa; Riganti Fabrizio; Giordano Roberta; Picu Andreea; Balbo Marcella; Van der Lely Aart Jan; Ghigo Ezio; Arvat Emanuela
Ghrelin does not mediate the somatotroph and corticotroph responses to the stimulatory effect of glucagon or insulin-induced hypoglycaemia in humans.
Clinical endocrinology 2004;60(6):699-704.
2004: Lanfranco F; Gianotti L; Picu A; Fassino S; Abbate Daga G; Mondelli V; Giordano R; Grottoli S; Ghigo E; Arvat E
The adrenal sensitivity to ACTH stimulation is preserved in anorexia nervosa.
Journal of endocrinological investigation 2004;27(5):436-41.
2004: Broglio Fabio; Gottero Cristina; Van Koetsveld Peter; Prodam Flavia; Destefanis Silvia; Benso Andrea; Gauna Carlotta; Hofland Leo; Arvat Emanuela; van der Lely Aart Jan; Ghigo Ezio
Acetylcholine regulates ghrelin secretion in humans.
The Journal of clinical endocrinology and metabolism 2004;89(5):2429-33.
2004: Lanfranco Fabio; Giordano Roberta; Pellegrino Micaela; Gianotti Laura; Ramunni Josefina; Picu Andreea; Baldi Matteo; Ghigo Ezio; Arvat Emanuela
Free fatty acids exert an inhibitory effect on adrenocorticotropin and cortisol secretion in humans.
The Journal of clinical endocrinology and metabolism 2004;89(3):1385-90.
2004: Giordano R; Pellegrino M; Oleandri S; Baldi M; Balbo M; Laureti S; Falorni A; Ghigo E; Arvat E
Adrenal sensitivity to adrenocorticotropin 1-24 is reduced in patients with autoimmune polyglandular syndrome.
The Journal of clinical endocrinology and metabolism 2004;89(2):675-80.
2004: Giordano Roberta; Picu Andreea; Broglio Fabio; Bonelli Lorenza; Baldi Matteo; Berardelli Rita; Ghigo Ezio; Arvat Emanuela
Ghrelin, hypothalamus-pituitary-adrenal (HPA) axis and Cushing's syndrome.
Pituitary 2004;7(4):243-8.
2003: Gianotti L; Veldhuis J D; Destefanis S; Lanfranco F; Ramunni J; Arvat E; Marzetto M; Boutignon F; Deghenghi R; Ghigo E
Suppression and recovery of LH secretion by a potent and selective GnRH-receptor antagonist peptide in healthy early follicular-phase women are mediated via selective control of LH secretory burst mass.
Clinical endocrinology 2003;59(4):526-32.
2003: Lanfranco F; Gianotti L; Giordano R; Pellegrino M; Maccario M; Arvat E
Ageing, growth hormone and physical performance.
Journal of endocrinological investigation 2003;26(9):861-72.
2003: Giordano Roberta; Grottoli Silvia; Brossa PierClaudio; Pellegrino Micaela; Destefanis Silvia; Lanfranco Fabio; Gianotti Laura; Ghigo Ezio; Arvat Emanuela
Alprazolam (a benzodiazepine activating GABA receptor) reduces the neuroendocrine responses to insulin-induced hypoglycaemia in humans.
Clinical endocrinology 2003;59(3):314-20.
2003: Fassino S; Lanfranco F; Abbate Daga G; Mondelli V; Destefanis S; Rovera G G; Camanni F; Ghigo E; Arvat E; Gianotti L
Prolonged treatment with glycerophosphocholine, an acetylcholine precursor, does not disclose the potentiating effect of cholinesterase inhibitors on GHRH-induced somatotroph secretion in anorexia nervosa.
Journal of endocrinological investigation 2003;26(6):503-7.
2003: Pinessi L; Rainero I; Valfrè W; Lo Giudice R; Ferrero M; Rivoiro C; Arvat E; Gianotti L; Del Rizzo P; Limone P
Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan.
Cephalalgia : an international journal of headache 2003;23(5):354-60.
2003: Lanfranco F; Gianotti L; Destefanis S; Arvat E; Ghigo E; Camanni F
[Endocrine abnormalities in anorexia nervosa]
Minerva endocrinologica 2003;28(2):169-80.
2003: Broglio Fabio; Benso Andrea; Castiglioni Carlotta; Gottero Cristina; Prodam Flavia; Destefanis Silvia; Gauna Carlotta; van der Lely Aart Jan; Deghenghi Romano; Bo Mario; Arvat Emanuela; Ghigo Ezio
The endocrine response to ghrelin as a function of gender in humans in young and elderly subjects.
The Journal of clinical endocrinology and metabolism 2003;88(4):1537-42.
2003: Broglio F; Benso A; Gottero C; Prodam F; Gauna C; Filtri L; Arvat E; van der Lely A J; Deghenghi R; Ghigo E
Non-acylated ghrelin does not possess the pituitaric and pancreatic endocrine activity of acylated ghrelin in humans.
Journal of endocrinological investigation 2003;26(3):192-6.
2003: Aimaretti G; Baffoni C; Di Vito L; Grottoli S; Gaia D; Gasco V; Giordano R; Zadik Z; Camanni F; Ghigo E; Arvat E
Hypopituitaric patients with corticotropin insufficiency show marked impairment of the cortisol response to ACTH (1-24) independently of the duration of the disease.
Journal of endocrinological investigation 2003;26(1):49-55.
2003: Broglio Fabio; Gottero Cristina; Benso Andrea; Prodam Flavia; Casanueva Felipe F; Dieguez Carlos; van der Lely Aart Jan; Deghenghi Romano; Arvat Emanuela; Ghigo Ezio
Acetylcholine does not play a major role in mediating the endocrine responses to ghrelin, a natural ligand of the GH secretagogue receptor, in humans.
Clinical endocrinology 2003;58(1):92-8.
2003: Broglio F; Arvat E; Gottero C; Benso A; Prodam F; Destefanis S; Aimaretti G; Papotti M; Muccioli G; Deghenghi R; Ghigo E
Natural and synthetic growth hormone secretagogues: do they have therapeutic potential?
Treatments in endocrinology 2003;2(3):153-63.
2003: Broglio Fabio; Gottero Cristina; Arvat Emanuela; Ghigo Ezio
Endocrine and non-endocrine actions of ghrelin.
Hormone research 2003;59(3):109-17.
2002: Leal-Cerro Alfonso; Torres Elena; Soto Alfonso; Dios Elena; Deghenghi Romano; Arvat Emanuela; Ghigo Ezio; Dieguez Carlos; Casanueva Felipe F
Ghrelin is no longer able to stimulate growth hormone secretion in patients with Cushing's syndrome but instead induces exaggerated corticotropin and cortisol responses.
Neuroendocrinology 2002;76(6):390-6.
2002: Broglio Fabio; Arvat Emanuela; Benso Andrea; Papotti Mauro; Muccioli Giampiero; Deghenghi Romano; Ghigo Ezio
Ghrelin: endocrine and non-endocrine actions.
Journal of pediatric endocrinology & metabolism : JPEM 2002;15 Suppl 5():1219-27.
2002: Laureti Stefano; Candeloro Paola; Aglietti Maria Chiara; Giordano Roberta; Arvat Emanuela; Ghigo Ezio; Santeusanio Fausto; Falorni Alberto
Dehydroepiandrosterone, 17alpha-hydroxyprogesterone and aldosterone responses to the low-dose (1 micro g) ACTH test in subjects with preclinical adrenal autoimmunity.
Clinical endocrinology 2002;57(5):677-83.
2002: Broglio Fabio; Koetsveld Pv Peter van; Benso Andrea; Gottero Cristina; Prodam Flavia; Papotti Mauro; Muccioli Giampiero; Gauna Carlotta; Hofland Leo; Deghenghi Romano; Arvat Emanuela; Van Der Lely Aart Jan; Ghigo Ezio
Ghrelin secretion is inhibited by either somatostatin or cortistatin in humans.
The Journal of clinical endocrinology and metabolism 2002;87(10):4829-32.
2002: Grottoli S; Giordano R; Maccagno B; Pellegrino M; Ghigo E; Arvat E
The stimulatory effect of canrenoate, a mineralocorticoid antagonist, on the activity of the hypothalamus-pituitary-adrenal axis is abolished by alprazolam, a benzodiazepine, in humans.
The Journal of clinical endocrinology and metabolism 2002;87(10):4616-20.
2002: Arvat Emanuela; Broglio Fabio; Aimaretti Gianluca; Benso Andrea; Giordano Roberta; Deghenghi Romano; Ghigo Ezio
Ghrelin and synthetic GH secretagogues.
Best practice & research. Clinical endocrinology & metabolism 2002;16(3):505-17.
2002: Broglio F; Boutignon F; Benso A; Gottero C; Prodam F; Arvat E; Ghè C; Catapano F; Torsello A; Locatelli V; Muccioli G; Boeglin D; Guerlavais V; Fehrentz J A; Martinez J; Ghigo E; Deghenghi R
EP1572: a novel peptido-mimetic GH secretagogue with potent and selective GH-releasing activity in man.
Journal of endocrinological investigation 2002;25(8):RC26-8.
2002: Arvat E; Giordano R; Grottoli S; Ghigo E
Benzodiazepines and anterior pituitary function.
Journal of endocrinological investigation 2002;25(8):735-47.
2002: Broglio Fabio; Arvat Emanuela; Benso Andrea; Gottero Cristina; Prodam Flavia; Granata Riccarda; Papotti Mauro; Muccioli Giampiero; Deghenghi Romano; Ghigo Ezio
Ghrelin: much more than a natural growth hormone secretagogue.
The Israel Medical Association journal : IMAJ 2002;4(8):607-13.
2002: Broglio Fabio; Arvat Emanuela; Benso Andrea; Gottero Cristina; Prodam Flavia; Grottoli Silvia; Papotti Mauro; Muccioli Giampiero; van der Lely Aart Jan; Deghenghi Romano; Ghigo Ezio
Endocrine activities of cortistatin-14 and its interaction with GHRH and ghrelin in humans.
The Journal of clinical endocrinology and metabolism 2002;87(8):3783-90.
2002: Broglio Fabio; Benso Andrea; Gottero Cristina; Prodam Flavia; Grottoli Silvia; Tassone Francesco; Maccario Mauro; Casanueva Felipe F; Dieguez Carlos; Deghenghi Romano; Ghigo Ezio; Arvat Emanuela
Effects of glucose, free fatty acids or arginine load on the GH-releasing activity of ghrelin in humans.
Clinical endocrinology 2002;57(2):265-71.
2002: Gianotti L; Lanfranco F; Ramunni J; Destefanis S; Ghigo E; Arvat E
GH/IGF-I axis in anorexia nervosa.
Eating and weight disorders : EWD 2002;7(2):94-105.
2002: Aimaretti Gianluca; Baffoni Claudia; Broglio Fabio; Janssen Joop A M; Corneli Ginevra; Deghenghi Romano; van der Lely Aart Jan; Ghigo Ezio; Arvat Emanuela
Endocrine responses to ghrelin in adult patients with isolated childhood-onset growth hormone deficiency.
Clinical endocrinology 2002;56(6):765-71.
2002: Grottoli S; Maccagno B; Ramunni J; Di Vito L; Giordano R; Gianotti L; DeStefanis S; Camanni F; Ghigo E; Arvat E
Alprazolam, a benzodiazepine, does not modify the ACTH and cortisol response to hCRH and AVP, but blunts the cortisol response to ACTH in humans.
Journal of endocrinological investigation 2002;25(5):420-5.
2002: Di Vito Lidia; Broglio Fabio; Benso Andrea; Gottero Cristina; Prodam Flavia; Papotti Mauro; Muccioli Giampiero; Dieguez Carlos; Casanueva Felipe F; Deghenghi Romano; Ghigo Ezio; Arvat Emanuela
The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans.
Clinical endocrinology 2002;56(5):643-8.
2002: Maccario Mauro; Veldhuis Johannes D; Broglio Fabio; Vito Lidia Di; Arvat Emanuela; Deghenghi Romano; Ghigo Ezio
Impact of two or three daily subcutaneous injections of hexarelin, a synthetic growth hormone (GH) secretagogue, on 24-h GH, prolactin, adrenocorticotropin and cortisol secretion in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2002;146(3):310-8.
2002: Giordano R; Rossetto R; Baffoni C; Lanfranco F; Aimaretti G L; Gianotti L; Grottoli S; Maccario M; Ghigo E; Arvat E
Adrenal sensitivity to ACTH1-24 as function of age, body weight and pituitary function.
Journal of endocrinological investigation 2002;25(10 Suppl):85-6.
2002: Gottero C; Benso A; Prodam F; Broglio F; Castiglioni C; Bo M; Deghenghi R; Ghigo E; Arvat E
Age-related variations of the GH response to GH secretagogues in humans.
Journal of endocrinological investigation 2002;25(10 Suppl):42-3.
2001: Broglio F; Benso A; Gottero C; Vito L D; Granata R; Arvat E; Bobbio M; Trevi G; Ghigo E
Effect of digoxin on the somatotroph responsiveness to growth hormone-releasing hormone (GHRH) alone or combined with arginine in normal young volunteers.
Clinical endocrinology 2001;55(6):755-8.
2001: Broglio F; Arvat E; Benso A; Gottero C; Muccioli G; Papotti M; van der Lely A J; Deghenghi R; Ghigo E
Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.
The Journal of clinical endocrinology and metabolism 2001;86(10):5083-6.
2001: Aimaretti G; Fanciulli G; Bellone S; Maccario M; Arvat E; Delitala G; Camanni F; Ghigo E
Enhancement of the peripheral sensitivity to growth hormone in adults with GH deficiency.
European journal of endocrinology / European Federation of Endocrine Societies 2001;145(3):267-72.
2001: Aimaretti G; Bellone S; Baffoni C; Cornel G; Origlia C; Di Vito L; Rovere S; Arvat E; Camanni F; Ghigo E
Short procedure of GHRH plus arginine test in clinical practice.
Pituitary 2001;4(3):129-34.
2001: Giordano R; Di Vito L; Lanfranco F; Broglio F; Benso A; Gianotti L; Grottoli S; Ghigo E; Arvat E
Elderly subjects show severe impairment of dehydroepiandrosterone sulphate and reduced sensitivity of cortisol and aldosterone response to the stimulatory effect of ACTH(1-24).
Clinical endocrinology 2001;55(2):259-65.
2001: Arvat E; Maccagno B; Giordano R; Pellegrino M; Broglio F; Gianotti L; Maccario M; Camanni F; Ghigo E
Mineralocorticoid receptor blockade by canrenoate increases both spontaneous and stimulated adrenal function in humans.
The Journal of clinical endocrinology and metabolism 2001;86(7):3176-81.
2001: Ghigo E; Aimaretti G; Arvat E; Camanni F
Growth hormone-releasing hormone combined with arginine or growth hormone secretagogues for the diagnosis of growth hormone deficiency in adults.
Endocrine 2001;15(1):29-38.
2001: Gualillo O; Caminos J E; Kojima M; Kangawa K; Arvat E; Ghigo E; Casanueva F F; Diéguez C
Gender and gonadal influences on ghrelin mRNA levels in rat stomach.
European journal of endocrinology / European Federation of Endocrine Societies 2001;144(6):687-90.
2001: Rainero I; Valfrè W; Savi L; Gentile S; Pinessi L; Gianotti L; Arvat E; Ghigo E; Del Rizzo P; Calvelli P; Limone P
Neuroendocrine effects of subcutaneous sumatriptan in patients with migraine.
Journal of endocrinological investigation 2001;24(5):310-4.
2001: Arvat E; Maccario M; Di Vito L; Broglio F; Benso A; Gottero C; Papotti M; Muccioli G; Dieguez C; Casanueva F F; Deghenghi R; Camanni F; Ghigo E
Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone.
The Journal of clinical endocrinology and metabolism 2001;86(3):1169-74.
2001: Ghigo E; Arvat E; Giordano R; Broglio F; Gianotti L; Maccario M; Bisi G; Graziani A; Papotti M; Muccioli G; Deghenghi R; Camanni F
Biologic activities of growth hormone secretagogues in humans.
Endocrine 2001;14(1):87-93.
2001: Arvat E; Gianotti L; Giordano R; Broglio F; Maccario M; Lanfranco F; Muccioli G; Papotti M; Graziani A; Ghigo E; Deghenghi R
Growth hormone-releasing hormone and growth hormone secretagogue-receptor ligands: focus on reproductive system.
Endocrine 2001;14(1):35-43.
2001: Broglio F; Benso A; Valetto M R; Gottero C; Quaranta L; Podio V; Arvat E; Bobbio M; Bisi G; Ghigo E
Growth hormone-independent cardiotropic activities of growth hormone-releasing peptides in normal subjects, in patients with growth hormone deficiency, and in patients with idiopathic or ischemic dilated cardiomyopathy.
Endocrine 2001;14(1):105-8.
2001: Gianotti L; Ramunni J; Lanfranco F; Maccagno B; Giordano R; Broglio F; Maccario M; Muller E E; Ghigo E; Arvat E
Recombinant human IGF-I does not modify the ACTH and cortisol responses to hCRH and hexarelin, a peptidyl GH secretagogue, in humans.
Journal of endocrinological investigation 2001;24(2):67-71.
2001: Maccario M; Tassone F; Gianotti L; Lanfranco F; Grottoli S; Arvat E; Muller E E; Ghigo E
Effects of recombinant human insulin-like growth factor I administration on the growth hormone (gh) response to GH-releasing hormone in obesity.
The Journal of clinical endocrinology and metabolism 2001;86(1):167-71.
2000: Peino R; Baldelli R; Rodriguez-Garcia J; Rodriguez-Segade S; Kojima M; Kangawa K; Arvat E; Ghigo E; Dieguez C; Casanueva F F
Ghrelin-induced growth hormone secretion in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(6):R11-4.
2000: Arvat E; Maccagno B; Ramunni J; Giordano R; DiVito L; Broglio F; Maccario M; Camanni F; Ghigo E
Glucagon is an ACTH secretagogue as effective as hCRH after intramuscolar administration while it is ineffective when given intravenously in normal subjects.
Pituitary 2000;3(3):169-73.
2000: Arvat E; Maccagno B; Ramunni J; Giordano R; Broglio F; Gianotti L; Maccario M; Camanni F; Ghigo E
Interaction between glucagon and hexarelin, a peptidyl GH secretagogue, on somatotroph and corticotroph secretion in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(5):601-6.
2000: Aimaretti G; Baffoni C; Bellone S; Di Vito L; Corneli G; Arvat E; Benso L; Camanni F; Ghigo E
Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test.
The Journal of clinical endocrinology and metabolism 2000;85(10):3693-9.
2000: Gianotti L; Maccario M; Lanfranco F; Ramunni J; Di Vito L; Grottoli S; Muller E E; Ghigo E; Arvat E
Arginine counteracts the inhibitory effect of recombinant human insulin-like growth factor I on the somatotroph responsiveness to growth hormone-releasing hormone in humans.
The Journal of clinical endocrinology and metabolism 2000;85(10):3604-8.
2000: MacCario M; Grottoli S; Divito L; Rossetto R; Tassone F; Ganzaroli C; Oleandri S E; Arvat E; Ghigo E
Adrenal responsiveness to high, low and very low ACTH 1-24 doses in obesity.
Clinical endocrinology 2000;53(4):437-44.
2000: Broglio F; Benso A; Gottero C; Muccioli G; Deghenghi R; Ghigo E; Arvat E
Endocrine activities of alexamorelin (Ala-His-d-2-methyl-Trp-Ala-Trp-d-Phe-Lys-NH2), a synthetic GH secretagogue, in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(3):419-25.
2000: Broglio F; Benso A; Arvat E; Aimaretti G; Gottero C; Granata R; Boghen M F; Bobbio M; Camanni F; Ghigo E
Normal IGF-I and enhanced IGFBP-3 response to very low rhGH dose in patients with dilated cardiomyopathy.
Journal of endocrinological investigation 2000;23(8):520-5.
2000: Arvat E; Di Vito L; Broglio F; Papotti M; Muccioli G; Dieguez C; Casanueva F F; Deghenghi R; Camanni F; Ghigo E
Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans.
Journal of endocrinological investigation 2000;23(8):493-5.
2000: Arvat E; Di Vito L; Lanfranco F; Maccario M; Baffoni C; Rossetto R; Aimaretti G; Camanni F; Ghigo E
Stimulatory effect of adrenocorticotropin on cortisol, aldosterone, and dehydroepiandrosterone secretion in normal humans: dose-response study.
The Journal of clinical endocrinology and metabolism 2000;85(9):3141-6.
2000: Gianotti L; Pincelli A I; Scacchi M; Rolla M; Bellitti D; Arvat E; Lanfranco F; Torsello A; Ghigo E; Cavagnini F; Müller E E
Effects of recombinant human insulin-like growth factor I administration on spontaneous and growth hormone (GH)-releasing hormone-stimulated GH secretion in anorexia nervosa.
The Journal of clinical endocrinology and metabolism 2000;85(8):2805-9.
2000: Laureti S; Arvat E; Candeloro P; Di Vito L; Ghigo E; Santeusanio F; Falorni A
Low dose (1 microg) ACTH test in the evaluation of adrenal dysfunction in pre-clinical Addison's disease.
Clinical endocrinology 2000;53(1):107-15.
2000: Arvat E; Maccagno B; Ramunni J; Maccario M; Giordano R; Broglio F; Camanni F; Ghigo E
Interaction between glucagon and human corticotropin-releasing hormone or vasopressin on ACTH and cortisol secretion in humans.
European journal of endocrinology / European Federation of Endocrine Societies 2000;143(1):99-104.
2000: Grottoli S; Arvat E; Gauna C; Maccagno B; Ramunni J; Giordano R; Maccario M; Deghenghi R; Ghigo E
Alprazolam, a benzodiazepine, blunts but does not abolish the ACTH and cortisol response to hexarelin, a GHRP, in obese patients.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24 Suppl 2():S136-7.
2000: Maccario M; Grottoli S; Procopio M; Oleandri S E; Rossetto R; Gauna C; Arvat E; Ghigo E
The GH/IGF-I axis in obesity: influence of neuro-endocrine and metabolic factors.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2000;24 Suppl 2():S96-9.
2000: Gianotti L; Fassino S; Daga G A; Lanfranco F; De Bacco C; Ramunni J; Arvat E; MacCario M; Ghigo E
Effects of free fatty acids and acipimox, a lipolysis inhibitor, on the somatotroph responsiveness to GHRH in anorexia nervosa.
Clinical endocrinology 2000;52(6):713-20.
2000: Pinessi L; Rainero I; Savi L; Valfrè W; Limone P; Calvelli P; Del Rizzo P; Gianotti L; Taliano M; Ghigo E; Arvat E
Effects of subcutaneous sumatriptan on plasma growth hormone concentrations in migraine patients.
Cephalalgia : an international journal of headache 2000;20(4):223-7.
2000: Aimaretti G; Baffoni C; DiVito L; Bellone S; Grottoli S; Maccario M; Arvat E; Camanni F; Ghigo E
Comparisons among old and new provocative tests of GH secretion in 178 normal adults.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(4):347-52.
2000: Bellone J; Bellone S; Aimaretti G; Valetto M R; Baffoni C; Corneli G; Origlia C; Arvat E; Ghigo E
The negative GH auto-feedback in childhood: effects of rhGH and/or GHRH on the somatotroph response to GHRH or hexarelin, a peptidyl GH secretagogue, in children.
Journal of endocrinological investigation 2000;23(3):158-62.
2000: Broglio F; Benso A; Gottero C; Vito L D; Aimaretti G; Fubini A; Arvat E; Bobbio M; Ghigo E
Patients with dilated cardiomyopathy show reduction of the somatotroph responsiveness to GHRH both alone and combined with arginine.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(2):157-63.
2000: Ghigo E; Arvat E; Gianotti L; Lanfranco F; Broglio F; Aimaretti G; Maccario M; Camanni F
Hypothalamic growth hormone-insulin-like growth factor-I axis across the human life span.
Journal of pediatric endocrinology & metabolism : JPEM 2000;13 Suppl 6():1493-502.
1999: Grottoli S; Arvat E; Gauna C; Maccagno B; Ramunni J; Giordano R; Maccario M; Deghenghi R; Ghigo E
Effects of alprazolam, a benzodiazepine, on the ACTH-, GH- and PRL-releasing activity of hexarelin, a synthetic peptidyl GH secretagogue (GHS), in patients with simple obesity and in patients with Cushing's disease.
Pituitary 1999;2(3):197-204.
1999: Procopio M; Maccario M; Savio P; Valetto M R; Aimaretti G; Grottoli S; Oleandri S E; Baffoni C; Tassone F; Arvat E; Camanni F; Ghigo E
GH response to GHRH combined with pyridostigmine or arginine in different conditions of low somatotrope secretion in adulthood: obesity and Cushing's syndrome in comparison with hypopituitarism.
Minerva endocrinologica 1999;24(3-4):107-11.
1999: Arvat E; Ramunni J; Maccagno B; Giordano R; Broglio F; Deghenghi R; Boscaro M; Ghigo E
Corticotropin-releasing effect of hexarelin, a peptidyl GH secretagogue, in normal subjects pretreated with metyrapone or RU-486, a glucocorticoid receptor antagonist, and in patients with Addison's disease.
Neuroendocrinology 1999;70(3):200-6.
1999: Arvat E; Maccagno B; Ramunni J; Di Vito L; Giordano R; Gianotti L; Broglio F; Camanni F; Ghigo E
The inhibitory effect of alprazolam, a benzodiazepine, overrides the stimulatory effect of metyrapone-induced lack of negative cortisol feedback on corticotroph secretion in humans.
The Journal of clinical endocrinology and metabolism 1999;84(8):2611-5.
1999: Ghigo E; Aimaretti G; Maccario M; Fanciulli G; Arvat E; Minuto F; Giordano G; Delitala G; Camanni F
Dose-response study of GH effects on circulating IGF-I and IGFBP-3 levels in healthy young men and women.
The American journal of physiology 1999;276(6 Pt 1):E1009-13.
1999: Broglio F; Fubini A; Morello M; Arvat E; Aimaretti G; Gianotti L; Boghen M F; Deghenghi R; Mangiardi L; Ghigo E
Activity of GH/IGF-I axis in patients with dilated cardiomyopathy.
Clinical endocrinology 1999;50(4):417-30.
1999: Arvat E; Giordano R; Gianotti L; Broglio F; Camanni F; Ghigo E
Neuroendocrinology of the human growth hormone-insulin-like growth factor I axis during ageing.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1999;9 Suppl A():111-5.
1999: Bisi G; Podio V; Valetto M R; Broglio F; Bertuccio G; Del Rio G; Arvat E; Boghen M F; Deghenghi R; Muccioli G; Ong H; Ghigo E
Acute cardiovascular and hormonal effects of GH and hexarelin, a synthetic GH-releasing peptide, in humans.
Journal of endocrinological investigation 1999;22(4):266-72.
1999: Arvat E; Di Vito L; Lanfranco F; Broglio F; Giordano R; Benso A; Muccioli G P; Deghenghi R; Ghigo E
Tyr-Ala-Hexarelin, a synthetic octapeptide, possesses the same endocrine activities of Hexarelin and GHRP-2 in humans.
Journal of endocrinological investigation 1999;22(2):91-7.
1999: Gianotti L; Rolla M; Arvat E; Belliti D; Valetto M R; Ferdeghini M; Ghigo E; Müller E E
Effect of somatostatin infusion on the somatotrope responsiveness to growth hormone-releasing hormone in patients with anorexia nervosa.
Biological psychiatry 1999;45(3):334-9.
1999: Arvat E; Ramunni J; Giordano R; Maccagno B; Broglio F; Benso A; Deghenghi R; Ghigo E
Effects of the combined administration of hexarelin, a synthetic peptidyl GH secretagogue, and hCRH on ACTH, cortisol and GH secretion in patients with Cushing's disease.
Journal of endocrinological investigation 1999;22(1):23-8.
1999: Ghigo E; Gianotti L; Arvat E; Ramunni J; Valetto M R; Broglio F; Rolla M; Cavagnini F; Müller E E
Effects of recombinant human insulin-like growth factor I administration on growth hormone (GH) secretion, both spontaneous and stimulated by GH-releasing hormone or hexarelin, a peptidyl GH secretagogue, in humans.
The Journal of clinical endocrinology and metabolism 1999;84(1):285-90.
1999: Giordano R; Arvat E; Maccagno B; Di Vito L; Lanfranco F; Broglio F; Camanni F
Corticotroph and adrenal responsiveness to hCRH, hexarelin and ACTH in young and elderly subjects.
Journal of endocrinological investigation 1999;22(10 Suppl):82.
1999: Benso A; Broglio F; Gottero C; Di Vito L; Arvat E; Bobbio M; Ghigo E
Activity of GH/IGF-I axis in patients with dilated cardiomyopathy.
Journal of endocrinological investigation 1999;22(10 Suppl):63.
1999: Broglio F; Benso A; Gottero C; Quaranta L; Arvat E; Bobbio M; Ghigo E
The GH response to GHRH in normal adults is not affected by enalapril or furosemide while is blunted by digoxin.
Journal of endocrinological investigation 1999;22(10 Suppl):61-2.
1999: Lanfranco F; Ceda G P; Ramunni J; Aimaretti G; Gianotti L; Di Vito L; Arvat E; Camanni F; Ghigo E
The IGF-I response to very low rhGH doses is preserved in human aging.
Journal of endocrinological investigation 1999;22(10 Suppl):59-60.
1999: Ramunni J; Ragusa L; Arvat E; Gianotti L; Maccagno B; Giordano R; Pettinato R; Barone C; Romano C; Ghigo E
Young adults with Down's syndrome show increased corticotrope responsiveness to hCRH or hexarelin, a peptidyl GH secretagogue.
Journal of endocrinological investigation 1999;22(10 Suppl):57-8.
1999: Ghigo E; Arvat E; Broglio F; Giordano R; Gianotti L; Muccioli G; Papotti M; Graziani A; Bisi G; Deghenghi R; Camanni F
Endocrine and non-endocrine activities of growth hormone secretagogues in humans.
Hormone research 1999;51 Suppl 3():9-15.
1998: Arvat E; Ceda G; Ramunni J; Lanfranco F; Aimaretti G; Gianotti L; Broglio F; Ghigo E
The IGF-I response to very low rhGH doses is preserved in human ageing.
Clinical endocrinology 1998;49(6):757-63.
1998: Arvat E; Maccagno B; Ramunni J; Broglio F; Lanfranco F; Giordano R; Benso A; Deghenghi R; Ghigo E
Influence of galanin and serotonin on the endocrine response to Hexarelin, a synthetic peptidyl GH-secretagogue, in normal women.
Journal of endocrinological investigation 1998;21(10):673-9.
1998: Bellone J; Bartolotta E; Sgattoni C; Aimaretti G; Arvat E; Bellone S; Deghenghi R; Ghigo E
Hexarelin, a synthetic GH-releasing peptide, is a powerful stimulus of GH secretion in pubertal children and in adults but not in prepubertal children and in elderly subjects.
Journal of endocrinological investigation 1998;21(8):494-500.
1998: Ghigo E; Arvat E; Aimaretti G; Broglio F; Giordano R; Camanni F
Diagnostic and therapeutic uses of growth hormone-releasing substances in adult and elderly subjects.
Baillière's clinical endocrinology and metabolism 1998;12(2):341-58.
1998: Gianotti L; Broglio F; Ramunni J; Lanfranco F; Gauna C; Benso A; Zanello M; Arvat E; Ghigo E
The activity of GH/IGF-I axis in anorexia nervosa and in obesity: a comparison with normal subjects and patients with hypopituitarism or critical illness.
Eating and weight disorders : EWD 1998;3(2):64-70.
1998: Arvat E; Maccagno B; Ramunni J; Di Vito L; Gianotti L; Broglio F; Benso A; Deghenghi R; Camanni F; Ghigo E
Effects of dexamethasone and alprazolam, a benzodiazepine, on the stimulatory effect of hexarelin, a synthetic GHRP, on ACTH, cortisol and GH secretion in humans.
Neuroendocrinology 1998;67(5):310-6.
1998: Aimaretti G; Corneli G; Razzore P; Bellone S; Baffoni C; Arvat E; Camanni F; Ghigo E
Comparison between insulin-induced hypoglycemia and growth hormone (GH)-releasing hormone + arginine as provocative tests for the diagnosis of GH deficiency in adults.
The Journal of clinical endocrinology and metabolism 1998;83(5):1615-8.
1998: Arvat E; Ceda G P; Di Vito L; Ramunni J; Gianotti L; Broglio F; Deghenghi R; Ghigo E
Age-related variations in the neuroendocrine control, more than impaired receptor sensitivity, cause the reduction in the GH-releasing activity of GHRPs in human aging.
Pituitary 1998;1(1):51-8.
1998: Ghigo E; Arvat E; Camanni F
Growth hormone secretagogues as corticotrophin-releasing factors.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl B():145-8.
1998: Muccioli G; Ghè C; Ghigo M C; Papotti M; Arvat E; Boghen M F; Nilsson M H; Deghenghi R; Ong H; Ghigo E
Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland.
The Journal of endocrinology 1998;157(1):99-106.
1998: Procopio M; Maccario M; Savio P; Valetto M R; Aimaretti G; Grottoli S; Oleandri S E; Baffoni C; Tassone F; Arvat E; Camanni F; Ghigo E
GH response to GHRH combined with pyridostigmine or arginine in different conditions of low somatotrope secretion in adulthood: obesity and Cushing's syndrome in comparison with hypopituitarism.
Panminerva medica 1998;40(1):13-7.
1998: Beccaria L; Marziani E; Manzoni P; Arvat E; Valetto M R; Gianotti L; Ghigo E; Chiumello G
Further evidence of cholinergic impairment of the neuroendocrine control of the GH secretion in Down's syndrome.
Dementia and geriatric cognitive disorders 1998;9(2):78-81.
1998: Ghigo E; Aimaretti G; Corneli G; Bellone J; Arvat E; Maccario M; Camanni F
Diagnosis of GH deficiency in adults.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 1998;8 Suppl A():55-8.
1998: Gianotti L; Broglio F; Aimaretti G; Arvat E; Colombo S; Di Summa M; Gallioli G; Pittoni G; Sardo E; Stella M; Zanello M; Miola C; Ghigo E
Low IGF-I levels are often uncoupled with elevated GH levels in catabolic conditions.
Journal of endocrinological investigation 1998;21(2):115-21.
1998: Gianotti L; Arvat E; Valetto M R; Ramunni J; Di Vito L; Maccagno B; Camanni F; Ghigo E
Effects of beta-adrenergic agonists and antagonists on the growth hormone response to growth hormone-releasing hormone in anorexia nervosa.
Biological psychiatry 1998;43(3):181-7.
1998: Camanni F; Ghigo E; Arvat E
Growth hormone-releasing peptides and their analogs.
Frontiers in neuroendocrinology 1998;19(1):47-72.
1997: Arvat E; Ramunni J; Bellone J; Di Vito L; Baffoni C; Broglio F; Deghenghi R; Bartolotta E; Ghigo E
The GH, prolactin, ACTH and cortisol responses to Hexarelin, a synthetic hexapeptide, undergo different age-related variations.
European journal of endocrinology / European Federation of Endocrine Societies 1997;137(6):635-42.
1997: Arvat E; Maccagno B; Ramunni J; Di Vito L; Broglio F; Deghenghi R; Camanni F; Ghigo E
Hexarelin, a synthetic growth-hormone releasing peptide, shows no interaction with corticotropin-releasing hormone and vasopressin on adrenocorticotropin and cortisol secretion in humans.
Neuroendocrinology 1997;66(6):432-8.
1997: Grottoli S; Razzore P; Arvat E; Oleandri S E; Rossetto R; Ciccarelli E; Camanni F; Ghigo E
Reduction of the somatotrope responsiveness to GHRH and Hexarelin but not to arginine plus GHRH in hyperprolactinemic patients.
Journal of endocrinological investigation 1997;20(10):597-602.
1997: Arvat E; Camanni F; Ghigo E
Age-related growth hormone-releasing activity of growth hormone secretagogues in humans.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1997;423():92-6.
1997: Arvat E; Di Vito L; Ramunni J; Gianotti L; Giordano R; Deghenghi R; Camanni F; Ghigo E
Low hexarelin dose and pyridostigmine have additive effect and potentiate to the same extent the GHRH-induced GH response in man.
Clinical endocrinology 1997;47(4):495-500.
1997: Bartolotta E; Bellone J; Aimaretti G; Arvat E; Benso L; Deghenghi R; Camanni F; Ghigo E
The GH-releasing effect of Hexarelin, a synthetic hexapeptide, in newborns is lower than in young adults.
Journal of pediatric endocrinology & metabolism : JPEM 1997;10(5):491-7.
1997: Ghigo E; Arvat E; Ramunni J; Colao A; Gianotti L; Deghenghi R; Lombardi G; Camanni F
Adrenocorticotropin- and cortisol-releasing effect of hexarelin, a synthetic growth hormone-releasing peptide, in normal subjects and patients with Cushing's syndrome.
The Journal of clinical endocrinology and metabolism 1997;82(8):2439-44.
1997: Arvat E; Gianotti L; Broglio F; Maccagno B; Bertagna A; Deghenghi R; Camanni F; Ghigo E
Oestrogen replacement does not restore the reduced GH-releasing activity of Hexarelin, a synthetic hexapeptide, in post-menopausal women.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(5):483-7.
1997: Ghigo E; Arvat E; Muccioli G; Camanni F
Growth hormone-releasing peptides.
European journal of endocrinology / European Federation of Endocrine Societies 1997;136(5):445-60.
1997: Martina V; Bruno G; Tagliabue M; Maccario M; Bertaina S; Zumpano E; Arvat E; Ghigo E; Camanni F
Repeated administration of growth hormone-releasing hormone with or without previous administration of pyridostigmine in insulin-dependent diabetes mellitus.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1997;29(4):180-3.
1997: Arvat E; Maccagno B; Ramunni J; Gianotti L; Di Vito L; Deghenghi R; Camanni F; Ghigo E
Effects of histaminergic antagonists on the GH-releasing activity of GHRH or hexarelin, a synthetic hexapeptide, in man.
Journal of endocrinological investigation 1997;20(3):122-7.
1997: Maccario M; Valetto M R; Savio P; Aimaretti G; Baffoni C; Procopio M; Grottoli S; Oleandri S E; Arvat E; Ghigo E
Maximal secretory capacity of somatotrope cells in obesity: comparison with GH deficiency.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 1997;21(1):27-32.
1997: Arvat E; Di Vito L; Gianotti L; Ramunni J; Boghen M F; Deghenghi R; Camanni F; Ghigo E
Mechanisms underlying the negative growth hormone (GH) autofeedback on the GH-releasing effect of hexarelin in man.
Metabolism: clinical and experimental 1997;46(1):83-8.
1997: Arvat E; di Vito L; Maccagno B; Broglio F; Boghen M F; Deghenghi R; Camanni F; Ghigo E
Effects of GHRP-2 and hexarelin, two synthetic GH-releasing peptides, on GH, prolactin, ACTH and cortisol levels in man. Comparison with the effects of GHRH, TRH and hCRH.
Peptides 1997;18(6):885-91.
1996: Grottoli S; Arvat E; Gianotti L; Ramunni J; Di Vito L; Maccagno B; Ciccarelli E; Camanni F; Ghigo E
Galanin positively modulates prolactin secretion in normal women.
Journal of endocrinological investigation 1996;19(11):739-44.
1996: Grottoli S; Maccario M; Procopio M; Oleandri S E; Arvat E; Gianotti L; Deghenghi R; Camanni F; Ghigo E
Somatotrope responsiveness to Hexarelin, a synthetic hexapeptide, is refractory to the inhibitory effect of glucose in obesity.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(6):678-82.
1996: Valetto M R; Bellone J; Baffoni C; Savio P; Aimaretti G; Gianotti L; Arvat E; Camanni F; Ghigo E
Reproducibility of the growth hormone response to stimulation with growth hormone-releasing hormone plus arginine during lifespan.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(5):568-72.
1996: Bellone J; Aimaretti G; Valetto M R; Bellone S; Baffoni C; Arvat E; Seminara S; Camanni F; Ghigo E
Acute administration of recombinant human growth hormone inhibits the somatotrope responsiveness to growth hormone-releasing hormone in childhood.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):421-4.
1996: Ghigo E; Arvat E; Gianotti L; Grottoli S; Rizzi G; Ceda G P; Boghen M F; Deghenghi R; Camanni F
Short-term administration of intranasal or oral Hexarelin, a synthetic hexapeptide, does not desensitize the growth hormone responsiveness in human aging.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(4):407-12.
1996: Arvat E; Gianotti L; Ragusa L; Valetto M R; Cappa M; Aimaretti G; Ramunni J; Grottoli S; Camanni F; Ghigo E
The enhancing effect of pyridostigmine on the GH response to GHRH undergoes an accelerated age-related reduction in Down syndrome.
Dementia (Basel, Switzerland) 1996;7(5):288-92.
1996: Ghigo E; Arvat E; Gianotti L; Ramunni J; DiVito L; Maccagno B; Grottoli S; Camanni F
Human aging and the GH-IGF-I axis.
Journal of pediatric endocrinology & metabolism : JPEM 1996;9 Suppl 3():271-8.
1996: Ghigo E; Aimaretti G; Gianotti L; Bellone J; Arvat E; Camanni F
New approach to the diagnosis of growth hormone deficiency in adults.
European journal of endocrinology / European Federation of Endocrine Societies 1996;134(3):352-6.
1996: Arvat E; Gianotti L; Ramunni J; DiVito L; Deghenghi R; Camanni F; Ghigo E
Influence of beta-adrenergic agonists and antagonists on the GH-releasing effect of Hexarelin in man.
Journal of endocrinological investigation 1996;19(1):25-9.
1996: Ciccarelli E; Grottoli S; Razzore P; Gianotti L; Arvat E; Deghenghi R; Camanni G; Ghigo E
Hexarelin, a synthetic growth hormone releasing peptide, stimulates prolactin secretion in acromegalic but not in hyperprolactinaemic patients.
Clinical endocrinology 1996;44(1):67-71.
1995: Müller E E; Rolla M; Ghigo E; Belliti D; Arvat E; Andreoni A; Torsello A; Locatelli V; Camanni F
Involvement of brain catecholamines and acetylcholine in growth hormone hypersecretory states. Pathophysiological, diagnostic and therapeutic implications.
Drugs 1995;50(5):805-37.
1995: Arvat E; Gianotti L; Ramunni J; Grottoli S; Brossa P C; Bertagna A; Camanni F; Ghigo E
Effect of galanin on basal and stimulated secretion of prolactin, gonadotropins, thyrotropin, adrenocorticotropin and cortisol in humans.
European journal of endocrinology / European Federation of Endocrine Societies 1995;133(3):300-4.
1995: Arvat E; Ramunni J; Gianotti L; Di Vito L; Maccario M; Camanni F; Ghigo E
Interaction of salbutamol and galanin on both basal and growth hormone releasing hormone-stimulated growth hormone secretion in humans.
Journal of endocrinological investigation 1995;18(5):324-8.
1995: Maccario M; Arvat E; Procopio M; Gianotti L; Grottoli S; Imbimbo B P; Lenaerts V; Deghenghi R; Camanni F; Ghigo E
Metabolic modulation of the growth hormone-releasing activity of hexarelin in man.
Metabolism: clinical and experimental 1995;44(1):134-8.
1995: Arvat E; Gianotti L; Di Vito L; Imbimbo B P; Lenaerts V; Deghenghi R; Camanni F; Ghigo E
Modulation of growth hormone-releasing activity of hexarelin in man.
Neuroendocrinology 1995;61(1):51-6.
1994: Arvat E; Gianotti L; Grottoli S; Imbimbo B P; Lenaerts V; Deghenghi R; Camanni F; Ghigo E
Arginine and growth hormone-releasing hormone restore the blunted growth hormone-releasing activity of hexarelin in elderly subjects.
The Journal of clinical endocrinology and metabolism 1994;79(5):1440-3.
1994: Ghigo E; Arvat E; Rizzi G; Goffi S; Grottoli S; Mucci M; Boghen M F; Camanni F
Growth hormone-releasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal aging.
European journal of endocrinology / European Federation of Endocrine Societies 1994;131(5):499-503.
1994: Ghigo E; Arvat E; Gianotti L; Nicolosi M; Valetto M R; Avagnina S; Bellitti D; Rolla M; Müller E E; Camanni F
Arginine but not pyridostigmine, a cholinesterase inhibitor, enhances the GHRH-induced GH rise in patients with anorexia nervosa.
Biological psychiatry 1994;36(10):689-95.
1994: Ghigo E; Arvat E; Gianotti L; Ramunni J; Maccario M; Camanni F
Interaction of salbutamol with pyridostigmine and arginine on both basal and GHRH-stimulated GH secretion in humans.
Clinical endocrinology 1994;40(6):799-802.
1994: Mazza E; Ghigo E; Boffano G; Valetto M; Maccario M; Arvat E; Bellone J; Procopio M; Müller E E; Camanni F
Effects of direct and indirect acetylcholine receptor agonists on growth hormone secretion in humans.
European journal of pharmacology 1994;254(1-2):17-20.
1994: Ghigo E; Arvat E; Gianotti L; Imbimbo B P; Lenaerts V; Deghenghi R; Camanni F
Growth hormone-releasing activity of hexarelin, a new synthetic hexapeptide, after intravenous, subcutaneous, intranasal, and oral administration in man.
The Journal of clinical endocrinology and metabolism 1994;78(3):693-8.
1994: Ghigo E; Arvat E; Rizzi G; Bellone J; Nicolosi M; Boffano G M; Mucci M; Boghen M F; Camanni F
Arginine enhances the growth hormone-releasing activity of a synthetic hexapeptide (GHRP-6) in elderly but not in young subjects after oral administration.
Journal of endocrinological investigation 1994;17(3):157-62.
1994: Mazza E; Goffi S; Barchi P; Arvat E; Bellone J; Limone P; Ghigo E; Camanni F
Enhanced adrenocorticotrophic hormone and cortisol responses to corticotrophin-releasing hormone in central idiopathic diabetes insipidus.
European journal of endocrinology / European Federation of Endocrine Societies 1994;130(2):121-4.
1993: Ghigo E; Nicolosi M; Arvat E; Marcone A; Danelon F; Mucci M; Franceschi M; Smirne S; Camanni F
Growth hormone secretion in Alzheimer's disease: studies with growth hormone-releasing hormone alone and combined with pyridostigmine or arginine.
Dementia (Basel, Switzerland) 1993;4(6):315-20.
1993: Arvat E; Gianotti L; Goffi S; Maccario M; Bellone J; Procopio M; Camanni F; Ghigo E
[Neuroregulation of GH secretion in aging]
Minerva endocrinologica 1993;18(3 Suppl 1):14-20.
1993: Bellone J; Bartolotta E; Cardinale G; Arvat E; Cherubini V; Aimaretti G; Maccario M; Mucci M; Camanni F; Ghigo E
Low dose orally administered arginine is able to enhance both basal and growth hormone-releasing hormone-induced growth hormone secretion in normal short children.
Journal of endocrinological investigation 1993;16(7):521-5.
1993: Ghigo E; Arvat E; Bellone J; Ramunni J; Camanni F
Neurotransmitter control of growth hormone secretion in humans.
The Journal of pediatric endocrinology 1993;6(3-4):263-6.
1993: Ghigo E; Procopio M; Maccario M; Bellone J; Arvat E; Campana S; Boghen M F; Camanni F
Repetitive GHRH administration fails to increase the response to GHRH in obese subjects. Evidence for a somatotrope defect in obesity?
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1993;25(6):305-8.
1993: Bellone J; Ghigo E; Procopio M; Arvat E; Valente F; Boffano G M; Maccario M; Dentelli P; Camanni F
Comparison of the potentiating effect of pyridostigmine, arginine and propranolol on the GHRH-induced GH release in short children.
Panminerva medica 1993;35(1):1-4.
1993: Arvat E; Cappa M; Casanueva F F; Dieguez C; Ghigo E; Nicolosi M; Valcavi R; Zini M
Pyridostigmine potentiates growth hormone (GH)-releasing hormone-induced GH release in both men and women.
The Journal of clinical endocrinology and metabolism 1993;76(2):374-7.
1993: Müller E E; Cocchi D; Ghigo E; Arvat E; Locatelli V; Camanni F
Growth hormone response to GHRH during lifespan.
The Journal of pediatric endocrinology 1993;6(1):5-13.
1992: Martina V; Miola C; Maccario M; Talliano M; Arvat E; Ghigo E; Camanni F
Inhibition by salbutamol of GHRH-induced GH release in type 1 diabetes mellitus.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 1992;24(11):520-3.
1992: Ghigo E; Goffi S; Arvat E; Imperiale E; Boffano G M; Valetto M R; Mazza E; Santi I; Magliona A; Boghen M F
A neuroendocrinological approach to evidence an impairment of central cholinergic function in aging.
Journal of endocrinological investigation 1992;15(9):665-70.
1992: Ghigo E; Miola C; Aimaretti G; Valente F; Procopio M; Arvat E; Yin-Zhang W; Camanni F
Arginine abolishes the inhibitory effect of glucose on the growth hormone response to growth hormone-releasing hormone in man.
Metabolism: clinical and experimental 1992;41(9):1000-3.
1992: Ghigo E; Procopio M; Boffano G M; Arvat E; Valente F; Maccario M; Mazza E; Camanni F
Arginine potentiates but does not restore the blunted growth hormone response to growth hormone-releasing hormone in obesity.
Metabolism: clinical and experimental 1992;41(5):560-3.
1992: Arvat E; Ghigo E; Nicolosi M; Boffano G M; Bellone J; Yin-Zhang W; Mazza E; Camanni F
Galanin reinstates the growth hormone response to repeated growth hormone-releasing hormone administration in man.
Clinical endocrinology 1992;36(4):347-50.
1992: Terzolo M; Piovesan A; Pia A; Arvat E; Bellone J; Valente F; Paccotti P; Ghigo E; Angeli A
Similarity of the nocturnal profile of serum melatonin at early puberty and early adulthood.
Chronobiologia 1992;19(1-2):81-7.
1992: Ghigo E; Maccario M; Arvat E; Valetto M R; Valente F; Nicolosi M; Mazza E; Martina V; Cocchi D; Camanni F
Interactions of galanin and arginine on growth hormone, prolactin, and insulin secretion in man.
Metabolism: clinical and experimental 1992;41(1):85-9.
1991: Ghigo E; Arvat E; Valente F; Nicolosi M; Boffano G M; Procopio M; Bellone J; Maccario M; Mazza E; Camanni F
Arginine reinstates the somatotrope responsiveness to intermittent growth hormone-releasing hormone administration in normal adults.
Neuroendocrinology 1991;54(3):291-4.
1990: Ghigo E; Goffi S; Nicolosi M; Arvat E; Valente F; Mazza E; Ghigo M C; Camanni F
Growth hormone (GH) responsiveness to combined administration of arginine and GH-releasing hormone does not vary with age in man.
The Journal of clinical endocrinology and metabolism 1990;71(6):1481-5.
1990: Ghigo E; Bellone J; Arvat E; Mazza E; Cellat S G; Brambilla F; Müller E E; Camanni F
Effects of alpha- and Beta-adrenergic agonists and antagonists on growth hormone secretion in man.
Journal of neuroendocrinology 1990;2(4):473-6.
1990: Ghigo E; Arvat E; Nicolosi M; Bellone J; Valetto M R; Mazza E; Imperiale E; Procopio M; Ghigo M C; Camanni F
Acute clonidine administration potentiates spontaneous diurnal, but not nocturnal, growth hormone secretion in normal short children.
The Journal of clinical endocrinology and metabolism 1990;71(2):433-5.
1990: Ghigo E; Goffi S; Arvat E; Nicolosi M; Procopio M; Bellone J; Imperiale E; Mazza E; Baracchi G; Camanni F
Pyridostigmine partially restores the GH responsiveness to GHRH in normal aging.
Acta endocrinologica 1990;123(2):169-73.
1990: Ghigo E; Bellone J; Imperiale E; Arvat E; Mazza E; Valetto M R; Boffano G M; Cappa M; Loche S; De Sanctis C
Pyridostigmine potentiates L-dopa- but not arginine- and galanin-induced growth hormone secretion in children.
Neuroendocrinology 1990;52(1):42-5.
1990: Ghigo E; Imperiale E; Boffano G M; Mazza E; Bellone J; Arvat E; Procopio M; Goffi S; Barreca A; Chiabotto P
A new test for the diagnosis of growth hormone deficiency due to primary pituitary impairment: combined administration of pyridostigmine and growth hormone-releasing hormone.
Journal of endocrinological investigation 1990;13(4):307-16.
1990: Mazza E; Ghigo E; Bellone J; Arvat E; Revelli E; Cella S G; Brambilla F; Müller E E; Camanni F
Effects of alpha- and beta-adrenergic agonists and antagonists on growth hormone secretion in man.
Endocrinologia experimentalis 1990;24(1-2):211-9.
1990: Ghigo E; Arvat E; Nicolosi M; Mazza E; Camanni F
Comparison of growth hormone-releasing effect of growth hormone-releasing hormone, clonidine and pyridostigmine in normal children and adolescents. GH-releasing effect of GHRH, clonidine and pyridostigmine.
Panminerva medica 1990;32(1):1-3.
1990: Ghigo E; Arvat E; Mazza E; Mondardini A; Cappa M; Müller E E; Cammani F
Failure of pyridostigmine to increase both basal and GHRH-induced GH secretion in the night.
Acta endocrinologica 1990;122(1):37-40.
1990: Ghigo E; Mazza E; Bellone J; Arvat E; Imperiale E; Procopio M; Camanni F
Neuroactive drugs in growth disorders.
Acta paediatrica Scandinavica. Supplement 1990;367():33-7.
1989: Mazza E; Ghigo E; Goffi S; Procopio M; Imperiale E; Arvat E; Bellone J; Boghen M F; Müller E E; Camanni F
Effect of the potentiation of cholinergic activity on the variability in individual GH response to GH-releasing hormone.
Journal of endocrinological investigation 1989;12(11):795-8.
1989: Ghigo E; Mazza E; Corrias A; Imperiale E; Goffi S; Arvat E; Bellone J; De Sanctis C; Müller E E; Camanni F
Effect of cholinergic enhancement by pyridostigmine on growth hormone secretion in obese adults and children.
Metabolism: clinical and experimental 1989;38(7):631-3.
1989: Ghigo E; Goffi S; Mazza E; Arvat E; Procopio M; Bellone J; Müller E E; Camanni F
Repeated GH-releasing hormone administration unravels different GH secretory patterns in normal adults and children.
Acta endocrinologica 1989;120(5):598-601.
1989: Ghigo E; Goffi S; Mazza E; Imperiale E; Arvat E; Bellone J; Procopio M; Müller E E; Camanni F
Acute administration of pyridostigmine and clonidine has an additive stimulatory effect on GH release in normal children.
Journal of endocrinological investigation 1989;12(2):99-101.

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