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Margaret Harnett

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William Harnett; Margaret M Harnett
Reply.
Justyna Rzepecka; Ivonne Siebeke; Christina N Steiger; Dorothy E Kean; Charles McSharry; Lamyaa Al-Riyami; Jennifer C Coltherd; Margaret M Harnett; William Harnett
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype.
Verica Paunovic; Margaret M Harnett
Mitogen-activated protein kinases as therapeutic targets for rheumatoid arthritis.

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2013: William Harnett; Margaret M Harnett
Reply.
Arthritis and rheumatism 2013;65(5):1403-4.
2013: Justyna Rzepecka; Ivonne Siebeke; Christina N Steiger; Dorothy E Kean; Charles McSharry; Lamyaa Al-Riyami; Jennifer C Coltherd; Margaret M Harnett; William Harnett
The helminth product, ES-62, protects against airway inflammation by resetting the Th cell phenotype.
International journal for parasitology 2013;43(3-4):211-23.
2013: Verica Paunovic; Margaret M Harnett
Mitogen-activated protein kinases as therapeutic targets for rheumatoid arthritis.
Drugs 2013;73(2):101-15.
2013: Dimity H Ball; Kara S Bell; Michelle L Coates; William Harnett; Justyna Rzepecka; Hwee Kee Tay; Lamyaa Al-Riyami; Margaret M Harnett
Mast Cell Subsets and Their Functional Modulation by the Acanthocheilonema viteae Product ES-62.
Journal of parasitology research 2013;2013():961268.
2012: Verica Paunovic; Theresa Thalhamer; Erica Lacey; Alison M Michie; Derek Blair; Natalie A Carter; Brian Gordon; Margaret M Harnett
Immune complex-mediated co-ligation of the BCR with FcγRIIB results in homeostatic apoptosis of B cells involving Fas signalling that is defective in the MRL/Lpr model of systemic lupus erythematosus.
Journal of autoimmunity 2012;39(4):332-46.
2012: Miguel A Pineda; Justyna Rzepecka; Pauline C Smith; Lamyaa Al-Riyami; J Alastair Gracie; William Harnett; Mairi A McGrath; Margaret M Harnett
The parasitic helminth product ES-62 suppresses pathogenesis in collagen-induced arthritis by targeting the interleukin-17-producing cellular network at multiple sites.
Arthritis and rheumatism 2012;64(10):3168-78.
2011: Mairi A McGrath; Angela Morton; Margaret M Harnett
Laser scanning cytometry: capturing the immune system in situ.
Methods in cell biology 2011;102():231-60.
2010: William Harnett; Margaret M Harnett
Helminth-derived immunomodulators: can understanding the worm produce the pill?
Nature reviews. Immunology 2010;10(4):278-84.
2010: Margaret M Harnett; Alirio J Melendez; William Harnett
The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease.
Clinical and experimental immunology 2010;159(3):256-67.
2009: William Harnett; Margaret M Harnett
Immunomodulatory activity and therapeutic potential of the filarial nematode secreted product, ES-62.
Advances in experimental medicine and biology 2009;666():88-94.
2008: William Harnett; Margaret M Harnett
Lymphocyte hyporesponsiveness during filarial nematode infection.
Parasite immunology 2008;30(9):447-53.
2008: William Harnett; Margaret M Harnett
Parasitic nematode modulation of allergic disease.
Current allergy and asthma reports 2008;8(5):392-7.
2008: Margaret M Harnett; Dorothy E Kean; A Boitelle; S McGuiness; T Thalhamer; C N Steiger; C Egan; L Al-Riyami; Marcos J C Alcocer; Katrina M Houston; J Alastair Gracie; Iain B McInnes; William Harnett
The phosphorycholine moiety of the filarial nematode immunomodulator ES-62 is responsible for its anti-inflammatory action in arthritis.
Annals of the rheumatic diseases 2008;67(4):518-23.
2008: Fraser A Marshall; Katherine A Watson; Paul Garside; Margaret M Harnett; William Harnett
Effect of activated antigen-specific B cells on ES-62-mediated modulation of effector function of heterologous antigen-specific T cells in vivo.
Immunology 2008;123(3):411-25.
2008: William Harnett; Margaret M Harnett
Therapeutic immunomodulators from nematode parasites.
Expert reviews in molecular medicine 2008;10():e18.
2007: Angela Morton; Barbara McManus; Paul Garside; Allan McI Mowat; Margaret M Harnett
Inverse Rap1 and phospho-ERK expression discriminate the maintenance phase of tolerance and priming of antigen-specific CD4+ T cells in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(12):8026-34.
2007: Margaret M Harnett
Laser scanning cytometry: understanding the immune system in situ.
Nature reviews. Immunology 2007;7(11):897-904.
2007: Helen Goodridge; S McGuiness; Katrina M Houston; CA Egan; L Al-Riyami; Marcos J C Alcocer; Margaret M Harnett; William Harnett
Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.
Parasite immunology 2007;29(3):127-37.
2006: William Harnett; Margaret M Harnett
Molecular basis of worm-induced immunomodulation.
Parasite immunology 2006;28(10):535-43.
2006: Dorothy E Kean; Helen Goodridge; Stephen McGuinness; Margaret M Harnett; Marcos J C Alcocer; William Harnett
Differential polarization of immune responses by plant 2S seed albumins, Ber e 1, and SFA8.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1561-6.
2006: Margaret M Harnett
Immunology. B cells spread and gather.
Science (New York, N.Y.) 2006;312(5774):709-10.
2006: William Harnett; Margaret M Harnett
Filarial nematode secreted product ES-62 is an anti-inflammatory agent: therapeutic potential of small molecule derivatives and ES-62 peptide mimetics.
Clinical and experimental pharmacology & physiology 2006;33(5-6):511-8.
2006: William Harnett; Margaret M Harnett
What causes lymphocyte hyporesponsiveness during filarial nematode infection?
Trends in parasitology 2006;22(3):105-10.
2006: Dorothy E Kean; Isao Ohtsuka; K Sato; Noriyasu Hada; Tadahiro Takeda; Günter Lochnit; Rudolf Geyer; Margaret M Harnett; William Harnett
Dissecting Ascaris glycosphingolipids for immunomodulatory moieties--the use of synthetic structural glycosphingolipid analogues.
Parasite immunology 2006;28(3):69-76.
2006: CA Egan; Katrina M Houston; Marcos J C Alcocer; Alexandra S Solovyova; Rothwelle Tate; Günter Lochnit; Iain B McInnes; Margaret M Harnett; R Geyer; Olwyn Byron; William Harnett
Lack of immunological cross-reactivity between parasite-derived and recombinant forms of ES-62, a secreted protein of Acanthocheilonema viteae.
Parasitology 2006;132(Pt 2):263-74.
2005: Fraser A Marshall; Angela Morton; Paul Garside; William Harnett; Margaret M Harnett
ES-62, an immunomodulator secreted by filarial nematodes, suppresses clonal expansion and modifies effector function of heterologous antigen-specific T cells in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5817-26.
2005: Helen Goodridge; Gillian Stepek; William Harnett; Margaret M Harnett
Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES-62.
Immunology 2005;115(3):296-304.
2005: Angela Morton; Paul Mitchell; Claire L Adams; Allan McI Mowat; James M Brewer; Margaret M Harnett; Paul Garside
Direct quantitation of T cell signaling by laser scanning cytometry.
Journal of immunological methods 2005;301(1-2):140-53.
2005: Margaret M Harnett; Elad Katz; Catriona A Ford
Differential signalling during B-cell maturation.
Immunology letters 2005;98(1):33-44.
2005: William Harnett; Helen Goodridge; Margaret M Harnett
Subversion of immune cell signal transduction pathways by the secreted filarial nematode product, ES-62.
Parasitology 2005;130 Suppl():S63-8.
2005: Helen Goodridge; Margaret M Harnett
Introduction to immune cell signalling.
Parasitology 2005;130 Suppl():S3-9.
2005: Helen Goodridge; Fraser A Marshall; Kathryn J Else; Katrina M Houston; Caitlin Egan; Lamyaa Al-Riyami; Foo Y Liew; William Harnett; Margaret M Harnett
Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):284-93.
2005: Helen Goodridge; Maureen R Deehan; William Harnett; Margaret M Harnett
Subversion of immunological signalling by a filarial nematode phosphorylcholine-containing secreted product.
Cellular signalling 2005;17(1):11-6.
2004: Helen Goodridge; Fraser A Marshall; Emma H Wilson; Katrina M Houston; Foo Y Liew; Margaret M Harnett; William Harnett
In vivo exposure of murine dendritic cell and macrophage bone marrow progenitors to the phosphorylcholine-containing filarial nematode glycoprotein ES-62 polarizes their differentiation to an anti-inflammatory phenotype.
Immunology 2004;113(4):491-8.
2004: N A Carter; Margaret M Harnett
Dissection of the signalling mechanisms underlying FcgammaRIIB-mediated apoptosis of mature B-cells.
Biochemical Society transactions 2004;32(Pt 6):973-5.
2004: Claire L Adams; Angela Morton; Allan McI Mowat; Margaret M Harnett; Paul Garside
Differences in the kinetics, amplitude, and localization of ERK activation in anergy and priming revealed at the level of individual primary T cells by laser scanning cytometry.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1579-86.
2004: David J Welsh; Margaret M Harnett; Margaret MacLean; Andrew J Peacock
Proliferation and signaling in fibroblasts: role of 5-hydroxytryptamine2A receptor and transporter.
American journal of respiratory and critical care medicine 2004;170(3):252-9.
2004: William Harnett; Iain B McInnes; Margaret M Harnett
ES-62, a filarial nematode-derived immunomodulator with anti-inflammatory potential.
Immunology letters 2004;94(1-2):27-33.
2004: Margaret M Harnett
CD40: a growing cytoplasmic tale.
Science's STKE : signal transduction knowledge environment 2004;2004(237):pe25.
2004: William Harnett; Margaret M Harnett; Bernard P Leung; J Alastair Gracie; Iain B McInnes
The anti-inflammatory potential of the filarial nematode secreted product, ES-62.
Current topics in medicinal chemistry 2004;4(5):553-9.
2004: Kirsty S Brown; Derek Blair; Steven D Reid; Emma K Nicholson; Margaret M Harnett
FcgammaRIIb-mediated negative regulation of BCR signalling is associated with the recruitment of the MAPkinase-phosphatase, Pac-1, and the 3'-inositol phosphatase, PTEN.
Cellular signalling 2004;16(1):71-80.
2004: Elad Katz; Caroline Lord; Catriona A Ford; Stephen B Gauld; Natalie A Carter; Margaret M Harnett
Bcl-(xL) antagonism of BCR-coupled mitochondrial phospholipase A(2) signaling correlates with protection from apoptosis in WEHI-231 B cells.
Blood 2004;103(1):168-76.
2003: Rosemary E Smith; Vanshree Patel; Sandra D Seatter; Maureen R Deehan; Marion H Brown; Gary Brooke; Helen Goodridge; Christopher J Howard; Kevin Rigley; William Harnett; Margaret M Harnett
A novel MyD-1 (SIRP-1alpha) signaling pathway that inhibits LPS-induced TNFalpha production by monocytes.
Blood 2003;102(7):2532-40.
2003: Iain B McInnes; Bernard P Leung; Margaret M Harnett; J Alastair Gracie; Foo Y Liew; William Harnett
A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(4):2127-33.
2003: Emma H Wilson; Elad Katz; Helen Goodridge; Margaret M Harnett; William Harnett
In vivo activation of murine peritoneal B1 cells by the filarial nematode phosphorylcholine-containing glycoprotein ES-62.
Parasite immunology 2003;25(8-9):463-6.
2003: Helen Goodridge; William Harnett; Foo Y Liew; Margaret M Harnett
Differential regulation of interleukin-12 p40 and p35 induction via Erk mitogen-activated protein kinase-dependent and -independent mechanisms and the implications for bioactive IL-12 and IL-23 responses.
Immunology 2003;109(3):415-25.
2003: Emma H Wilson; Maureen R Deehan; Elad Katz; Kirsty S Brown; Katrina M Houston; John O'Grady; Margaret M Harnett; William Harnett
Hyporesponsiveness of murine B lymphocytes exposed to the filarial nematode secreted product ES-62 in vivo.
Immunology 2003;109(2):238-45.
2003: William Harnett; Margaret M Harnett; Olwyn Byron
Structural/functional aspects of ES-62--a secreted immunomodulatory phosphorylcholine-containing filarial nematode glycoprotein.
Current protein & peptide science 2003;4(1):59-71.
2003: Claire J Ackerman; Margaret M Harnett; William Harnett; Sharon M Kelly; Dmitri I Svergun; Olwyn Byron
19 A solution structure of the filarial nematode immunomodulatory protein, ES-62.
Biophysical journal 2003;84(1):489-500.
2002: Angus J M Cameron; Kenneth J McDonald; Margaret M Harnett; Janet M Allen
Differentiation of the human monocyte cell line, U937, with dibutyryl cyclicAMP induces the expression of the inhibitory Fc receptor, FcgammaRIIb.
Immunology letters 2002;83(3):171-9.
2002: Maureen R Deehan; Helen Goodridge; Derek Blair; Günter Lochnit; Roger D Dennis; Rudolf Geyer; Margaret M Harnett; William Harnett
Immunomodulatory properties of Ascaris suum glycosphingolipids - phosphorylcholine and non-phosphorylcholine-dependent effects.
Parasite immunology 2002;24(9-10):463-9.
2002: Stephen B Gauld; Derek Blair; Catriona A Moss; Steven D Reid; Margaret M Harnett
Differential roles for extracellularly regulated kinase-mitogen-activated protein kinase in B cell antigen receptor-induced apoptosis and CD40-mediated rescue of WEHI-231 immature B cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3855-64.
2001: Alirio J Melendez; L Bruetschy; R Andres Floto; Margaret M Harnett; Janet M Allen
Functional coupling of FcgammaRI to nicotinamide adenine dinucleotide phosphate (reduced form) oxidative burst and immune complex trafficking requires the activation of phospholipase D1.
Blood 2001;98(12):3421-8.
2001: David J Welsh; Andrew J Peacock; Margaret MacLean; Margaret M Harnett
Chronic hypoxia induces constitutive p38 mitogen-activated protein kinase activity that correlates with enhanced cellular proliferation in fibroblasts from rat pulmonary but not systemic arteries.
American journal of respiratory and critical care medicine 2001;164(2):282-9.
2001: Helen Goodridge; Emma H Wilson; William Harnett; Carol C Campbell; Margaret M Harnett; Foo Y Liew
Modulation of macrophage cytokine production by ES-62, a secreted product of the filarial nematode Acanthocheilonema viteae.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):940-5.
2001: Maureen R Deehan; William Harnett; Margaret M Harnett
A filarial nematode-secreted phosphorylcholine-containing glycoprotein uncouples the B cell antigen receptor from extracellular signal-regulated kinase-mitogen-activated protein kinase by promoting the surface Ig-mediated recruitment of Src homology 2 domain-containing tyrosine phosphatase-1 and Pac-1 mitogen-activated kinase-phosphatase.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7462-8.
2001: Alirio J Melendez; Margaret M Harnett; Janet M Allen
Crosstalk between ARF6 and protein kinase Calpha in Fc(gamma)RI-mediated activation of phospholipase D1.
Current biology : CB 2001;11(11):869-74.
2001: William Harnett; Margaret M Harnett
Modulation of the host immune system by phosphorylcholine-containing glycoproteins secreted by parasitic filarial nematodes.
Biochimica et biophysica acta 2001;1539(1-2):7-15.
2001: Margaret M Harnett; William Harnett
Antigen receptor signaling is subverted by an immunomodulatory product secreted by a filarial nematode.
Archivum immunologiae et therapiae experimentalis 2001;49(4):263-9.
2001: Elad Katz; Maureen R Deehan; Sandra D Seatter; C Lord; R D Sturrock; Margaret M Harnett
B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(1):137-47.
2000: Katrina M Houston; Emma H Wilson; L Eyres; Frank Brombacher; Margaret M Harnett; James Alexander; William Harnett
Presence of phosphorylcholine on a filarial nematode protein influences immunoglobulin G subclass response to the molecule by an interleukin-10-dependent mechanism.
Infection and immunity 2000;68(9):5466-8.
2000: M Whelan; Margaret M Harnett; Katrina M Houston; Vanshree Patel; William Harnett; Kevin Rigley
A filarial nematode-secreted product signals dendritic cells to acquire a phenotype that drives development of Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6453-60.
1999: Gui-Jie Feng; Helen Goodridge; Margaret M Harnett; Xiao-Qing Wei; Andrei V Nikolaev; Adrian P Higson; Foo Y Liew
Extracellular signal-related kinase (ERK) and p38 mitogen-activated protein (MAP) kinases differentially regulate the lipopolysaccharide-mediated induction of inducible nitric oxide synthase and IL-12 in macrophages: Leishmania phosphoglycans subvert macrophage IL-12 production by targeting ERK MAP kinase.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6403-12.
1999: William Harnett; Maureen R Deehan; Katrina M Houston; Margaret M Harnett
Immunomodulatory properties of a phosphorylcholine-containing secreted filarial glycoprotein.
Parasite immunology 1999;21(12):601-8.
1999: DJ Gillooly; Alirio J Melendez; A R Hockaday; Margaret M Harnett; Janet M Allen
Endocytosis and vesicular trafficking of immune complexes and activation of phospholipase D by the human high-affinity IgG receptor requires distinct phosphoinositide 3-kinase activities.
The Biochemical journal 1999;344 Pt 2():605-11.
1999: Alirio J Melendez; Margaret M Harnett; Janet M Allen
FcgammaRI activation of phospholipase Cgamma1 and protein kinase C in dibutyryl cAMP-differentiated U937 cells is dependent solely on the tyrosine-kinase activated form of phosphatidylinositol-3-kinase.
Immunology 1999;98(1):1-8.
1999: Alirio J Melendez; Margaret M Harnett; Janet M Allen
Differentiation-dependent switch in protein kinase C isoenzyme activation by FcgammaRI, the human high-affinity receptor for immunoglobulin G.
Immunology 1999;96(3):457-64.
1999: William Harnett; Margaret M Harnett
Phosphorylcholine: friend or foe of the immune system?
Immunology today 1999;20(3):125-9.
1998: J J Gilbert; Trevor R Pettitt; Sandra D Seatter; Steven D Reid; Michael J O Wakelam; Margaret M Harnett
Antagonistic roles for phospholipase D activities in B cell signaling: while the antigen receptors transduce mitogenic signals via a novel phospholipase D activity, phosphatidylcholine-phospholipase D mediates antiproliferative signals.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(12):6575-84.
1998: Margaret M Harnett; Maureen R Deehan; D M Williams; William Harnett
Induction of signalling anergy via the T-cell receptor in cultured Jurkat T cells by pre-exposure to a filarial nematode secreted product.
Parasite immunology 1998;20(11):551-63.
1998: Maureen R Deehan; Gerry G B Klaus; Mary Holman; William Harnett; Margaret M Harnett
MAPkinase: a second site of G-protein regulation of B-cell activation via the antigen receptors.
Immunology 1998;95(2):169-77.
1998: Alirio J Melendez; R Andres Floto; DJ Gillooly; Margaret M Harnett; Janet M Allen
FcgammaRI coupling to phospholipase D initiates sphingosine kinase-mediated calcium mobilization and vesicular trafficking.
The Journal of biological chemistry 1998;273(16):9393-402.
1998: Maureen R Deehan; M J Frame; R M Parkhouse; Sandra D Seatter; Steven D Reid; Margaret M Harnett; William Harnett
A phosphorylcholine-containing filarial nematode-secreted product disrupts B lymphocyte activation by targeting key proliferative signaling pathways.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(6):2692-9.
1998: Alirio J Melendez; DJ Gillooly; Margaret M Harnett; Janet M Allen
Aggregation of the human high affinity immunoglobulin G receptor (FcgammaRI) activates both tyrosine kinase and G protein-coupled phosphoinositide 3-kinase isoforms.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(5):2169-74.
1998: Alirio J Melendez; R Andres Floto; Angus J M Cameron; DJ Gillooly; Margaret M Harnett; Janet M Allen
A molecular switch changes the signalling pathway used by the Fc gamma RI antibody receptor to mobilise calcium.
Current biology : CB 1998;8(4):210-21.
1998: William Harnett; Margaret M Harnett
Heterotrimeric Guanine Nucleotide-binding Proteins in Eukaryotic Parasites.
Parasitology today (Personal ed.) 1998;14(1):27-31.
1997: Maureen R Deehan; Margaret M Harnett; William Harnett
A filarial nematode secreted product differentially modulates expression and activation of protein kinase C isoforms in B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(12):6105-11.
1997: K R Grant; Margaret M Harnett; William Harnett
Acanthocheilonema viteae: stage-specific expression of G-protein alpha-subunits.
Experimental parasitology 1997;86(3):219-27.
1997: Sandra D Seatter; J J Gilbert; Margaret M Harnett
Lipid signalling in lymphocyte activation and cell death.
Biochemical Society transactions 1997;25(2):300S.
1997: Steven D Reid; Margaret M Harnett
CD40 signalling in B cell apoptosis and rescue.
Biochemical Society transactions 1997;25(2):299S.
1997: K R Grant; William Harnett; G Milligan; Margaret M Harnett
Differential G-protein expression during B- and T-cell development.
Immunology 1997;90(4):564-71.
1997: P A Reid; S D Gardner; D M Williams; Margaret M Harnett
The antigen receptors on mature and immature T lymphocytes are coupled to phosphatidylcholine-specific phospholipase D activation.
Immunology 1997;90(2):250-6.
1996: K R Grant; Margaret M Harnett; G Milligan; William Harnett
Characterization of heterotrimeric G-proteins in adult Acanthocheilonema viteae.
The Biochemical journal 1996;320 ( Pt 2)():459-66.
1996: J J Gilbert; A Stewart; C A Courtney; M C Fleming; P Reid; C G Jackson; A Wise; Michael J O Wakelam; Margaret M Harnett
Antigen receptors on immature, but not mature, B and T cells are coupled to cytosolic phospholipase A2 activation: expression and activation of cytosolic phospholipase A2 correlate with lymphocyte maturation.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(6):2054-61.
1996: A M Michie; M Lobban; T Müller; Margaret M Harnett; Miles D Houslay
Rapid regulation of PDE-2 and PDE-4 cyclic AMP phosphodiesterase activity following ligation of the T cell antigen receptor on thymocytes: analysis using the selective inhibitors erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA) and rolipram.
Cellular signalling 1996;8(2):97-110.
1996: Margaret M Harnett
Syk deficiency--a knockout for B-cell development.
Immunology today 1996;17(1):4.
1994: Margaret M Harnett
Assay of protein kinases and protein phosphorylation.
Methods in molecular biology (Clifton, N.J.) 1994;27():213-26.
1994: Margaret M Harnett
Analysis of G-proteins regulating signal transduction pathways.
Methods in molecular biology (Clifton, N.J.) 1994;27():199-211.
1993: William Harnett; Margaret M Harnett
Inhibition of murine B cell proliferation and down-regulation of protein kinase C levels by a phosphorylcholine-containing filarial excretory-secretory product.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(9):4829-37.
1993: C A Courtney; A Stewart; Michael J O Wakelam; Margaret M Harnett
The antigen receptors on B and T cells are not coupled to cytosolic phospholipase A2 activation and arachidonic acid release.
Biochemical Society transactions 1993;21(4):496S.
1993: J J Gilbert; Michael J O Wakelam; Margaret M Harnett
A role for phospholipase D activation in B cell activation.
Biochemical Society transactions 1993;21(4):493S.
1993: A Paul; A Stewart; Margaret M Harnett; Michael J O Wakelam
Changes in the activities and cellular localisation of phospholipases in differentiating HL-60 cells.
Biochemical Society transactions 1993;21(4):491S.
1993: William Cushley; Margaret M Harnett
Cellular signalling mechanisms in B lymphocytes.
The Biochemical journal 1993;292 ( Pt 2)():313-32.
1992: Margaret M Harnett; K Rigley
The role of G-proteins versus protein tyrosine kinases in the regulation of lymphocyte activation.
Immunology today 1992;13(12):482-6.
1991: Margaret M Harnett; M J Holman; Gerry G B Klaus
IL-4 promotes anti-Ig-mediated protein kinase C translocation and reverses phorbol ester-mediated protein kinase C down-regulation in murine B cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(11):3831-6.
1991: R J Phillips; Margaret M Harnett; Gerry G B Klaus
Antigen receptor-mediated phosphoinositide hydrolysis in murine T cells is not initiated via G-protein activation.
International immunology 1991;3(7):617-21.
1991: Gerry G B Klaus; Margaret M Harnett
Cross-talk between surface immunoglobulin and interleukin-4 receptors on murine B-lymphocytes.
Biochemical Society transactions 1991;19(2):272-5.
1990: Gerry G B Klaus; Margaret M Harnett
Cross-talk between B cell surface immunoglobulin and interleukin 4 receptors: the role of protein kinase C and Ca2(+)-mediated signals.
European journal of immunology 1990;20(10):2301-7.
1989: K P Rigley; Margaret M Harnett; R J Phillips; Gerry G B Klaus
Analysis of signaling via surface immunoglobulin receptors on B cells from CBA/N mice.
European journal of immunology 1989;19(11):2081-6.
1989: Margaret M Harnett; M J Holman; Gerry G B Klaus
Regulation of surface IgM- and IgD-mediated inositol phosphate formation and Ca2+ mobilization in murine B lymphocytes.
European journal of immunology 1989;19(10):1933-9.
1989: K P Rigley; Margaret M Harnett; Gerry G B Klaus
Co-cross-linking of surface immunoglobulin Fc gamma receptors on B lymphocytes uncouples the antigen receptors from their associated G protein.
European journal of immunology 1989;19(3):481-5.
1989: Gerry G B Klaus; Margaret M Harnett; K P Rigley
Regulation of the polyphosphoinositide-specific phosphodiesterase in B lymphocytes.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():723-31.
1989: Gerry G B Klaus; Margaret M Harnett; K P Rigley
G-protein regulation of polyphosphoinositide breakdown in B cells.
Advances in experimental medicine and biology 1989;254():95-100.
1988: Margaret M Harnett; Gerry G B Klaus
Protein kinase C activators inhibit the antigen receptor-coupled polyphosphoinositide phosphodiesterase in murine B lymphocytes.
FEBS letters 1988;239(2):281-4.
1988: Margaret M Harnett; Gerry G B Klaus
G protein coupling of antigen receptor-stimulated polyphosphoinositide hydrolysis in B cells.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):3135-9.
1987: Gerry G B Klaus; M K Bijsterbosch; A O'Garra; Margaret M Harnett; K P Rigley
Receptor signalling and crosstalk in B lymphocytes.
Immunological reviews 1987;99():19-38.