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Nigel Harris

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Rohan Willis; E Nigel Harris; Silvia S Pierangeli
Current international initiatives in antiphospholipid antibody testing.
Rohan Willis; E Nigel Harris; Silvia S Pierangeli
Pathogenesis of the antiphospholipid syndrome.
Silvia S Pierangeli; Angela Tincani; Richard C W Wong; Emmanuel J Favaloro; Gabriella Lakos; Pier Luigi Meroni; E Nigel Harris
Standards and reference materials for the anticardiolipin and anti-β2glycoprotein I assays: a report of recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies.

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All Publications

2012: Rohan Willis; E Nigel Harris; Silvia S Pierangeli
Current international initiatives in antiphospholipid antibody testing.
Seminars in thrombosis and hemostasis 2012;38(4):360-74.
2012: Rohan Willis; E Nigel Harris; Silvia S Pierangeli
Pathogenesis of the antiphospholipid syndrome.
Seminars in thrombosis and hemostasis 2012;38(4):305-21.
2012: Silvia S Pierangeli; Angela Tincani; Richard C W Wong; Emmanuel J Favaloro; Gabriella Lakos; Pier Luigi Meroni; E Nigel Harris
Standards and reference materials for the anticardiolipin and anti-β2glycoprotein I assays: a report of recommendations from the APL Task Force at the 13th International Congress on Antiphospholipid Antibodies.
Clinica chimica acta; international journal of clinical chemistry 2012;413(1-2):358-60.
2011: Silvia S Pierangeli; P G de Groot; J Dlott; E Favaloro; E Nigel Harris; G Lakos; T Ortel; Pier Luigi Meroni; K Otomo; V Pengo; Angela Tincani; R Wong; R Roubey
'Criteria' aPL tests: report of a task force and preconference workshop at the 13th International Congress on Antiphospholipid Antibodies, Galveston, Texas, April 2010.
Lupus 2011;20(2):182-90.
2008: Silvia S Pierangeli; E Nigel Harris
A quarter of a century in anticardiolipin antibody testing and attempted standardization has led us to here, which is?
Seminars in thrombosis and hemostasis 2008;34(4):313-28.
2006: R Budd; E Harley; Quarshie Alexander; V Henderson; E Nigel Harris; S S Pierangeli
A re-appraisal of the normal cut-off assignment for anticardiolipin IgM tests.
Journal of thrombosis and haemostasis : JTH 2006;4(10):2210-4.
2005: Silvia S Pierangeli; E Nigel Harris
Clinical laboratory testing for the antiphospholipid syndrome.
Clinica chimica acta; international journal of clinical chemistry 2005;357(1):17-33.
2005: Mariano Vega-Ostertag; Katie Casper; Robert Swerlick; Dardo E Ferrara; E Nigel Harris; Silvia S Pierangeli
Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies.
Arthritis and rheumatism 2005;52(5):1545-54.
2004: Mariano Vega-Ostertag; E Nigel Harris; Silvia S Pierangeli
Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin.
Arthritis and rheumatism 2004;50(9):2911-9.
2004: Dardo E Ferrara; Robert Swerlick; Katie Casper; Pier Luigi Meroni; Mariano Vega-Ostertag; E Nigel Harris; Silvia S Pierangeli
Fluvastatin inhibits up-regulation of tissue factor expression by antiphospholipid antibodies on endothelial cells.
Journal of thrombosis and haemostasis : JTH 2004;2(9):1558-63.
2004: Silvia S Pierangeli; Miri Blank; Xiaowei Liu; Ricardo G Espinola; Mati Fridkin; Mariano Vega Ostertag; Karen Roye-Green; E Nigel Harris; Yehuda Shoenfeld
A peptide that shares similarity with bacterial antigens reverses thrombogenic properties of antiphospholipid antibodies in vivo.
Journal of autoimmunity 2004;22(3):217-25.
2004: E Nigel Harris
Morehouse School of Medicine.
Journal of the Medical Association of Georgia 2004;93(3):43-7.
2004: Silvia S Pierangeli; Mariano Vega-Ostertag; E Nigel Harris
Intracellular signaling triggered by antiphospholipid antibodies in platelets and endothelial cells: a pathway to targeted therapies.
Thrombosis research 2004;114(5-6):467-76.
2004: E Nigel Harris; Silvia S Pierangeli
Primary, Secondary, Catastrophic Antiphospholipid Syndrome: is there a difference?
Thrombosis research 2004;114(5-6):357-61.
2003: Dardo E Ferrara; Xiaowei Liu; Ricardo G Espinola; Pier Luigi Meroni; Imad Abukhalaf; E Nigel Harris; Silvia S Pierangeli
Inhibition of the thrombogenic and inflammatory properties of antiphospholipid antibodies by fluvastatin in an in vivo animal model.
Arthritis and rheumatism 2003;48(11):3272-9.
2003: Ricardo G Espinola; Xiaowei Liu; Margaret Stanfield; J Hall; E Nigel Harris; Silvia S Pierangeli
E-Selectin mediates pathogenic effects of antiphospholipid antibodies.
Journal of thrombosis and haemostasis : JTH 2003;1(4):843-8.
2003: Silvia S Pierangeli; E Nigel Harris
Probing antiphospholipid-mediated thrombosis: the interplay between anticardiolipin antibodies and endothelial cells.
Lupus 2003;12(7):539-45.
2003: Azzudin E Gharavi; Silvia S Pierangeli; E Nigel Harris
Viral origin of antiphospholipid antibodies: endothelial cell activation and thrombus enhancement by CMV peptide-induced APL antibodies.
Immunobiology 2003;207(1):37-42.
2002: Gloria E Westney; E Nigel Harris
Catastrophic antiphospholipid syndrome in the intensive care unit.
Critical care clinics 2002;18(4):805-17.
2002: Chike M Nzerue; Karlene Hewan-Lowe; Silvia Pierangeli; E Nigel Harris
"Black swan in the kidney": renal involvement in the antiphospholipid antibody syndrome.
Kidney international 2002;62(3):733-44.
2002: Ricardo G Espinola; Silvia S Pierangeli; Azzudin E Gharavi; E Nigel Harris; Azzudin E Ghara
Hydroxychloroquine reverses platelet activation induced by human IgG antiphospholipid antibodies.
Thrombosis and haemostasis 2002;87(3):518-22.
2002: Azzudin E Gharavi; Silvia S Pierangeli; Ricardo G Espinola; Xiaowei Liu; Margaret Stanfield; E Nigel Harris
Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo.
Arthritis and rheumatism 2002;46(2):545-52.
2002: E Nigel Harris
Antirheumatic drugs in pregnancy.
Lupus 2002;11(10):683-9.
2002: E Nigel Harris; Silvia S Pierangeli
Revisiting the anticardiolipin test and its standardization.
Lupus 2002;11(5):269-75.
2002: E Nigel Harris; Silvia S Peirangeli; Azzudin E Gharavi
Antiphospholipid syndrome: diagnosis, pathogenesis, and management.
Journal of the Medical Association of Georgia 2002;91(1):31-4.
2001: Azzudin E Gharavi; Silvia S Pierangeli; E Nigel Harris
Origin of antiphospholipid antibodies.
Rheumatic diseases clinics of North America 2001;27(3):551-63.
2001: Silvia S Pierangeli; Ricardo G Espinola; Xiaowei Liu; E Nigel Harris; Jane E Salmon
Identification of an Fc gamma receptor-independent mechanism by which intravenous immunoglobulin ameliorates antiphospholipid antibody-induced thrombogenic phenotype.
Arthritis and rheumatism 2001;44(4):876-83.
2001: Silvia S Pierangeli; Azzudin E Gharavi; E Nigel Harris
Testing for antiphospholipid antibodies: problems and solutions.
Clinical obstetrics and gynecology 2001;44(1):48-57; quiz 58-9.
2001: Azzudin E Gharavi; Silvia S Pierangeli; R A Levy; E Nigel Harris
Mechanisms of pregnancy loss in antiphospholipid syndrome.
Clinical obstetrics and gynecology 2001;44(1):11-9.
2001: Silvia S Pierangeli; Ricardo G Espinola; Xiaowei Liu; E Nigel Harris
Thrombogenic effects of antiphospholipid antibodies are mediated by intercellular cell adhesion molecule-1, vascular cell adhesion molecule-1, and P-selectin.
Circulation research 2001;88(2):245-50.
2000: Silvia S Pierangeli; Azzudin E Gharavi; E Nigel Harris
Experimental thrombosis and antiphospholipid antibodies: new insights.
Journal of autoimmunity 2000;15(2):241-7.
2000: Azzudin E Gharavi; Silvia S Pierangeli; E Nigel Harris
New developments in viral peptides and APL induction.
Journal of autoimmunity 2000;15(2):227-30.
2000: E Nigel Harris; Silvia S Pierangeli
'Equivocal' antiphospholipid syndrome.
Journal of autoimmunity 2000;15(2):81-5.
1999: Xiaowei Liu; F W Peter; John Barker; Silvia S Pierangeli; E Nigel Harris; Gary L Anderson
Leukocyte-endothelium interaction in arterioles after ischemia and reperfusion.
The Journal of surgical research 1999;87(1):77-84.
1999: Azzudin E Gharavi; Silvia S Pierangeli; Margaret Stanfield; X W Liu; Ricardo G Espinola; E Nigel Harris
GDKV-induced antiphospholipid antibodies enhance thrombosis and activate endothelial cells in vivo and in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(5):2922-7.
1999: S S Pierangeli; L K Silva; E Nigel Harris
A flow cytometric assay for the detection of antiphospholipid antibodies.
American clinical laboratory 1999;18(6):18-9.
1999: W A Wilson; A E Gharavi; T Koike; Michael D Lockshin; D Ware Branch; J C Piette; Robin Brey; R Derksen; E Nigel Harris; G R Hughes; D A Triplett; M A Khamashta
International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome: report of an international workshop.
Arthritis and rheumatism 1999;42(7):1309-11.
1999: Silvia S Pierangeli; Margaret Stanfield; Xiaowei Liu; John Barker; G L Anderson; E Nigel Harris
Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo.
Circulation 1999;99(15):1997-2002.
1999: Peter A Merkel; Y Chang; S S Pierangeli; E Nigel Harris; RP Polisson
Comparison between the standard anticardiolipin antibody test and a new phospholipid test in patients with connective tissue diseases.
The Journal of rheumatology 1999;26(3):591-6.
1999: A L Clark; D Ware Branch; Robert M Silver; E Nigel Harris; SS Pierangeli; Joseph A Spinnato
Pregnancy complicated by the antiphospholipid syndrome: outcomes with intravenous immunoglobulin therapy.
Obstetrics and gynecology 1999;93(3):437-41.
1998: E Nigel Harris; Silvia S Pierangeli; Azzudin E Gharavi
Diagnosis of the antiphospholipid syndrome: a proposal for use of laboratory tests.
Lupus 1998;7 Suppl 2():S144-8.
1998: E Nigel Harris; Silvia S Pierangeli
Utilization of intravenous immunoglobulin therapy to treat recurrent pregnancy loss in the antiphospholipid syndrome: a review.
Scandinavian journal of rheumatology. Supplement 1998;107():97-102.
1998: Azzudin E Gharavi; S S Pierangeli; E E Gharavi; T Hua; X W Liu; John Barker; G H Anderson; E Nigel Harris
Thrombogenic properties of antiphospholipid antibodies do not depend on their binding to beta2 glycoprotein 1 (beta2GP1) alone.
Lupus 1998;7(5):341-6.
1998: Silvia S Pierangeli; M Stewart; L K Silva; E Nigel Harris
An antiphospholipid wet workshop: 7th International Symposium on Antiphospholipid Antibodies.
The Journal of rheumatology 1998;25(1):156-60.
1997: M H Edwards; SS Pierangeli; X Liu; John Barker; G Anderson; E Nigel Harris
Hydroxychloroquine reverses thrombogenic properties of antiphospholipid antibodies in mice.
Circulation 1997;96(12):4380-4.
1997: S Krnic-Barrie; C R O'Connor; Stephen Warwick Looney; S S Pierangeli; E Nigel Harris
A retrospective review of 61 patients with antiphospholipid syndrome. Analysis of factors influencing recurrent thrombosis.
Archives of internal medicine 1997;157(18):2101-8.
1997: E Nigel Harris; Silvia S Pierangeli
Antiphospholipid antibodies and cerebral lupus.
Annals of the New York Academy of Sciences 1997;823():270-8.
1997: Silvia S Pierangeli; G H Goldsmith; D Ware Branch; E Nigel Harris
Antiphospholipid antibody: functional specificity for inhibition of prothrombin activation by the prothrombinase complex.
British journal of haematology 1997;97(4):768-74.
1997: D Ware Branch; R Silver; SS Pierangeli; I van Leeuwen; E Nigel Harris
Antiphospholipid antibodies other than lupus anticoagulant and anticardiolipin antibodies in women with recurrent pregnancy loss, fertile controls, and antiphospholipid syndrome.
Obstetrics and gynecology 1997;89(4):549-55.
1997: Robert M Silver; SS Pierangeli; Samuel Edwin; F Umar; E Nigel Harris; James R Scott; D Ware Branch
Pathogenic antibodies in women with obstetric features of antiphospholipid syndrome who have negative test results for lupus anticoagulant and anticardiolipin antibodies.
American journal of obstetrics and gynecology 1997;176(3):628-33.
1996: S S Pierangeli; E Nigel Harris
In vivo models of thrombosis for the antiphospholipid syndrome.
Lupus 1996;5(5):451-5.
1996: E Nigel Harris; S S Pierangeli
Functional effects of anticardiolipin antibodies.
Lupus 1996;5(5):372-7.
1996: S S Pierangeli; S W Liu; G Anderson; John Barker; E Nigel Harris
Thrombogenic properties of murine anti-cardiolipin antibodies induced by beta 2 glycoprotein 1 and human immunoglobulin G antiphospholipid antibodies.
Circulation 1996;94(7):1746-51.
1996: S S Pierangeli; J Dean; G H Goldsmith; D Ware Branch; A Gharavi; E Nigel Harris
Studies on the interaction of placental anticoagulant protein I, beta 2 glycoprotein 1, and antiphospholipid antibodies in the prothrombinase reaction and in the solid phase anticardiolipin assays.
The Journal of laboratory and clinical medicine 1996;128(2):194-201.
1995: S S Pierangeli; X W Liu; John Barker; G Anderson; E Nigel Harris
Induction of thrombosis in a mouse model by IgG, IgM and IgA immunoglobulins from patients with the antiphospholipid syndrome.
Thrombosis and haemostasis 1995;74(5):1361-7.
1995: Douglas Borchman; E Nigel Harris; S S Pierangeli; O P Lamba
Interactions and molecular structure of cardiolipin and beta 2-glycoprotein 1 (beta 2-GP1).
Clinical and experimental immunology 1995;102(2):373-8.
1995: Robert M Silver; S S Pierangeli; A E Gharavi; E Nigel Harris; Samuel Edwin; Carolyn M Salafia; D Ware Branch
Induction of high levels of anticardiolipin antibodies in mice by immunization with beta 2-glycoprotein I does not cause fetal death.
American journal of obstetrics and gynecology 1995;173(5):1410-5.
1995: S P Walton; S S Pierangeli; A Campbell; E Klein; B Burchitt; E Nigel Harris
Demonstration of antiphospholipid antibody heterogeneity by phospholipid column chromatography and salt gradient elution techniques.
Lupus 1995;4(4):263-71.
1995: A M Hasnie; Marcus F Stoddard; C B Gleason; S G Wagner; R A Longaker; S Pierangeli; E Nigel Harris
Diastolic dysfunction is a feature of the antiphospholipid syndrome.
American heart journal 1995;129(5):1009-13.
1995: E Nigel Harris; G Goldsmith; S Pierangeli; A Gharavi; W Branch
Phospholipid binding antibodies warrant continued investigation.
Blood 1995;85(8):2276-7.
1995: A L Campbell; S S Pierangeli; S Wellhausen; E Nigel Harris
Comparison of the effects of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation.
Thrombosis and haemostasis 1995;73(3):529-34.
1995: Joseph A Spinnato; AL Clark; S S Pierangeli; E Nigel Harris
Intravenous immunoglobulin therapy for the antiphospholipid syndrome in pregnancy.
American journal of obstetrics and gynecology 1995;172(2 Pt 1):690-4.
1995: E Nigel Harris
The antiphospholipid syndrome. Diagnosis, management, and pathogenesis.
Clinical reviews in allergy & immunology 1995;13(1):39-48.
1994: S S Pierangeli; G H Goldsmith; S Krnic; E Nigel Harris
Differences in functional activity of anticardiolipin antibodies from patients with syphilis and those with antiphospholipid syndrome.
Infection and immunity 1994;62(9):4081-4.
1994: S S Pierangeli; E Nigel Harris
Antiphospholipid antibodies in an in vivo thrombosis model in mice.
Lupus 1994;3(4):247-51.
1994: E Nigel Harris; S Pierangeli
Anticardiolipin antibodies: specificity and function.
Lupus 1994;3(4):217-22.
1994: G H Goldsmith; S S Pierangeli; D Ware Branch; A E Gharavi; E Nigel Harris
Inhibition of prothrombin activation by antiphospholipid antibodies and beta 2-glycoprotein 1.
British journal of haematology 1994;87(3):548-54.
1994: S S Pierangeli; John Barker; D Stikovac; D Ackerman; G Anderson; J Barquinero; R Acland; E Nigel Harris
Effect of human IgG antiphospholipid antibodies on an in vivo thrombosis model in mice.
Thrombosis and haemostasis 1994;71(5):670-4.
1994: E Nigel Harris; S Pierangeli; D Birch
Anticardiolipin wet workshop report. Fifth International Symposium on antiphospholipid antibodies.
American journal of clinical pathology 1994;101(5):616-24.
1994: E Nigel Harris; S S Pierangeli
Antiphospholipid antibodies and the antiphospholipid syndrome.
Springer seminars in immunopathology 1994;16(2-3):223-45.
1993: Azzudin E Gharavi; E Nigel Harris; L R Sammaritano; S S Pierangeli; J Wen
Do patients with antiphospholipid syndrome have autoantibodies to beta 2-glycoprotein I?
The Journal of laboratory and clinical medicine 1993;122(4):426-31.
1993: S S Pierangeli; E Nigel Harris; A E Gharavi; G Goldsmith; D Ware Branch; W L Dean
Are immunoglobulins with lupus anticoagulant activity specific for phospholipids?
British journal of haematology 1993;85(1):124-32.
1993: S S Pierangeli; E Nigel Harris
Induction of phospholipid-binding antibodies in mice and rabbits by immunization with human beta 2 glycoprotein 1 or anticardiolipin antibodies alone.
Clinical and experimental immunology 1993;93(2):269-72.
1993: C B Gleason; Marcus F Stoddard; S G Wagner; R A Longaker; S Pierangeli; E Nigel Harris
A comparison of cardiac valvular involvement in the primary antiphospholipid syndrome versus anticardiolipin-negative systemic lupus erythematosus.
American heart journal 1993;125(4):1123-9.
1992: S S Pierangeli; E Nigel Harris; S A Davis; G DeLorenzo
Beta 2-glycoprotein 1 (beta 2GP1) enhances cardiolipin binding activity but is not the antigen for antiphospholipid antibodies.
British journal of haematology 1992;82(3):565-70.
1992: E Nigel Harris; S Pierangeli
Antiphospholipid antibodies: method of detection.
American journal of reproductive immunology (New York, N.Y. : 1989) 1992;28(3-4):208-10.
1992: E Nigel Harris
Serological detection of antiphospholipid antibodies.
Stroke; a journal of cerebral circulation 1992;23(2 Suppl):I3-6.
1992: C B Gleason; E Nigel Harris
The antiphospholipid syndrome: the clot thickens.
The Journal of the Kentucky Medical Association 1992;90(1):11-7.
1991: E Nigel Harris; Joseph A Spinnato
Should anticardiolipin tests be performed in otherwise healthy pregnant women?
American journal of obstetrics and gynecology 1991;165(5 Pt 1):1272-7.
1990: E Nigel Harris
Special report. The Second International Anti-cardiolipin Standardization Workshop/the Kingston Anti-Phospholipid Antibody Study (KAPS) group.
American journal of clinical pathology 1990;94(4):476-84.
1990: E Nigel Harris
A reassessment of the antiphospholipid syndrome.
The Journal of rheumatology 1990;17(6):733-5.
1990: E Nigel Harris
Antiphospholipid antibodies.
British journal of haematology 1990;74(1):1-9.
1989: E Nigel Harris
Anticardiolipin antibodies and autoimmune diseases.
Current opinion in rheumatology 1989;1(2):215-20.
1988: E Nigel Harris
Solid-phase anti-cardiolipin test revisited.
The American journal of medicine 1988;85(5):599-601.