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Prabhat Arya

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Combinatorial Chemistry Techniques

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TOP 3
Jyoti P Nandy; Michael Prakesch; Shahriar Khadem; P Thirupathi Reddy; Utpal Sharma; Prabhat Arya
Advances in solution- and solid-phase synthesis toward the generation of natural product-like libraries.
Rajamohan R Poondra; N Niranjan Kumar; Krikor Bijian; Michael Prakesch; Valérie Campagna-Slater; Ayub Reayi; P Thirupathi Reddy; Asna Choudhry; Michael L Barnes; Donald M Leek; Malgosia Daroszewska; Caroline Lougheed; Bin Xu; Matthieu Schapira; Moulay A Alaoui-Jamali; Prabhat Arya
Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways.
Jean-Louis Brochu; Michael Prakesch; Gary D Enright; Donald M Leek; Prabhat Arya
Reagent-based, modular, tandem Michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures.

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All Publications

2009: Jyoti P Nandy; Michael Prakesch; Shahriar Khadem; P Thirupathi Reddy; Utpal Sharma; Prabhat Arya
Advances in solution- and solid-phase synthesis toward the generation of natural product-like libraries.
Chemical reviews 2009;109(5):1999-2060.
2009: Rajamohan R Poondra; N Niranjan Kumar; Krikor Bijian; Michael Prakesch; Valérie Campagna-Slater; Ayub Reayi; P Thirupathi Reddy; Asna Choudhry; Michael L Barnes; Donald M Leek; Malgosia Daroszewska; Caroline Lougheed; Bin Xu; Matthieu Schapira; Moulay A Alaoui-Jamali; Prabhat Arya
Discovery of indoline-based, natural-product-like compounds as probes of focal adhesion kinase signaling pathways.
Journal of combinatorial chemistry 2009;11(2):303-9.
2008: Jean-Louis Brochu; Michael Prakesch; Gary D Enright; Donald M Leek; Prabhat Arya
Reagent-based, modular, tandem Michael approach for obtaining different indoline alkaloid-inspired polycyclic architectures.
Journal of combinatorial chemistry 2008;10(3):405-20.
2008: Jyoti P Nandy; Bojana Rakic; Bugga V N B Sarma; Nallareddy Babu; Marc Lefrance; Gary D Enright; Donald M Leek; Kate Daniel; Luc A Sabourin; Prabhat Arya
Benzofuran-derived cyclic beta-amino acid scaffold for building a diverse set of flavonoid-like probes and the discovery of a cell motility inhibitor.
Organic letters 2008;10(6):1143-6.
2006: P Thirupathi Reddy; S Quevillon; Zhonghong Gan; Nauzer Forbes; Donald M Leek; Prabhat Arya
Solution- and solid-phase, modular approaches for obtaining different natural product-like polycyclic architectures from an aminoindoline scaffold for combinatorial chemistry.
Journal of combinatorial chemistry 2006;8(6):856-71.
2006: Michael Prakesch; Stuti Srivastava; Donald M Leek; Prabhat Arya
Part 3. a novel stereocontrolled, in situ, solution- and solid-phase, Aza Michael approach for high-throughput generation of tetrahydroaminoquinoline-derived natural-product-like architectures.
Journal of combinatorial chemistry 2006;8(5):762-73.
2006: Utpal Sharma; Stuti Srivastava; Michael Prakesch; Maya Sharma; Donald M Leek; Prabhat Arya
Part 2: building diverse natural-product-like architectures from a tetrahydroaminoquinoline scaffold. Modular solution- and solid-phase approaches for use in high-throughput generation of chemical probes.
Journal of combinatorial chemistry 2006;8(5):735-61.
2006: Michael Prakesch; Utpal Sharma; Maya Sharma; Shahriar Khadem; Donald M Leek; Prabhat Arya
Part 1. modular approach to obtaining diverse tetrahydroquinoline-derived polycyclic skeletons for use in high-throughput generation of natural-product-like chemical probes.
Journal of combinatorial chemistry 2006;8(5):715-34.
2005: Ayub Reayi; Prabhat Arya
Natural product-like chemical space: search for chemical dissectors of macromolecular interactions.
Current opinion in chemical biology 2005;9(3):240-7.
2005: Zhonghong Gan; P Thirupathi Reddy; Sophie Quevillon; Samuel Couve-Bonnaire; Prabhat Arya
Stereocontrolled solid-phase synthesis of a 90-membered library of indoline-alkaloid-like polycycles from an enantioenriched aminoindoline scaffold.
Angewandte Chemie (International ed. in English) 2005;44(9):1366-8.
2005: Prabhat Arya; Reni Joseph; Zhonghong Gan; Bojana Rakic
Exploring new chemical space by stereocontrolled diversity-oriented synthesis.
Chemistry & biology 2005;12(2):163-80.
2004: Prabhat Arya; Samuel Couve-Bonnaire; Patricia Durieux; Daisy Laforce; Rohtash Kumar; Donald M Leek
Solution- and solid-phase synthesis of natural product-like tetrahydroquinoline-based polycyclics having a medium size ring.
Journal of combinatorial chemistry 2004;6(5):735-45.
2004: Shahriar Khadem; Reni Joseph; Majid Rastegar; Donald M Leek; Kostantin A Oudatchin; Prabhat Arya
A solution- and solid-phase approach to tetrahydroquinoline-derived polycyclics having a 10-membered ring.
Journal of combinatorial chemistry 2004;6(5):724-34.
2004: Samuel Couve-Bonnaire; Doug T H Chou; Zhonghong Gan; Prabhat Arya
A solid-phase, library synthesis of natural-product-like derivatives from an enantiomerically pure tetrahydroquinoline scaffold.
Journal of combinatorial chemistry 2004;6(1):73-7.
2004: Prabhat Arya; Chang-Qing Wei; Michael L Barnes; Malgosia Daroszewska
A solid phase library synthesis of hydroxyindoline-derived tricyclic derivatives by Mitsunobu approach.
Journal of combinatorial chemistry 2004;6(1):65-72.
2004: Prabhat Arya; Patricia Durieux; Zai-Xin Chen; Reni Joseph; Donald M Leek
Stereoselective diversity-oriented solution and solid-phase synthesis of tetrahydroquinoline-based polycyclic derivatives.
Journal of combinatorial chemistry 2004;6(1):54-64.
2002: Shlomo Antebi; Prabhat Arya; Leo E Manzer; Howard Alper
Carbonylation reactions of iodoarenes with PAMAM dendrimer-palladium catalysts immobilized on silica.
The Journal of organic chemistry 2002;67(19):6623-31.
2002: Prabhat Arya; Angela Barkley; Karla D Randell
Automated high-throughput synthesis of artificial glycopeptides. Small-molecule probes for chemical glycobiology.
Journal of combinatorial chemistry 2002;4(3):193-8.
2002: Karla D Randell; Angela Barkley; Prabhat Arya
High-throughput chemistry toward complex carbohydrates and carbohydrate-like compounds.
Combinatorial chemistry & high throughput screening 2002;5(2):179-93.
2002: Prabhat Arya; Reni Joseph; Doug T H Chou
Toward high-throughput synthesis of complex natural product-like compounds in the genomics and proteomics age.
Chemistry & biology 2002;9(2):145-56.
2001: Prabhat Arya; M Baek
Natural-product-like chiral derivatives by solid-phase synthesis.
Current opinion in chemical biology 2001;5(3):292-301.
2001: Prabhat Arya; G Panda; N V Rao; Howard Alper; S C Bourque; L E Manzer
Solid-phase catalysis: a biomimetic approach toward ligands on dendritic arms to explore recyclable hydroformylation reactions.
Journal of the American Chemical Society 2001;123(12):2889-90.
2001: Angela Barkley; Prabhat Arya
Combinatorial chemistry toward understanding the function(s) of carbohydrates and carbohydrate conjugates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(3):555-63.
2000: Prabhat Arya; KM Kutterer; Angela Barkley
Glycomimetics: a programmed approach toward neoglycopeptide libraries.
Journal of combinatorial chemistry 2000;2(2):120-6.
1999: Prabhat Arya; KM Kutterer; H Qin; J Roby; Michael L Barnes; S Lin; Clifford A Lingwood; M G Peter
Alpha-galactose based neoglycopeptides. Inhibition of verotoxin binding to globotriosylceramide.
Bioorganic & medicinal chemistry 1999;7(12):2823-33.
1998: Prabhat Arya; N Alibhai; H Qin; Graham W Burton; G Batist; S X You; M A Alaoui-Jamali
Design and synthesis of analogs of vitamin E: antiproliferative activity against human breast adenocarcinoma cells.
Bioorganic & medicinal chemistry letters 1998;8(18):2433-8.
1998: Prabhat Arya; KM Kutterer; H Qin; J Roby; Michael L Barnes; J M Kim; R Roy
Diversity of C-linked neoglycopeptides for the exploration of subsite-assisted carbohydrate binding interactions.
Bioorganic & medicinal chemistry letters 1998;8(10):1127-32.