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Paul Harris

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Solid-Phase Synthesis Techniques

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Publications

TOP 3
Kuo-yuan Hung; Paul W R Harris; Margaret A Brimble
Synthesis of the peptaibol framework of the anticancer agent culicinin D: stereochemical assignment of the AHMOD moiety.
Tom M Woods; Garth J S Cooper; Paul W R Harris; Meder Kamalov; Margaret A Brimble
Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides.
Paul W R Harris; Dong Jun Lee; Margaret A Brimble
A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography.

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All Publications

2012: Kuo-yuan Hung; Paul W R Harris; Margaret A Brimble
Synthesis of the peptaibol framework of the anticancer agent culicinin D: stereochemical assignment of the AHMOD moiety.
Organic letters 2012;14(22):5784-7.
2012: Tom M Woods; Garth J S Cooper; Paul W R Harris; Meder Kamalov; Margaret A Brimble
Synthesis of monolysyl advanced glycation endproducts and their incorporation into collagen model peptides.
Organic letters 2012;14(22):5740-3.
2012: Paul W R Harris; Dong Jun Lee; Margaret A Brimble
A slow gradient approach for the purification of synthetic polypeptides by reversed phase high performance liquid chromatography.
Journal of peptide science : an official publication of the European Peptide Society 2012;18(9):549-55.
2012: Mazdak Radjainia; Michael Schmitz; Yu Wang; Sung H Yang; Bo Bai; Margaret A Brimble; Michael D W Griffin; Paul W R Harris; Bosheng Huang; Alok K Mitra
A highly conserved tryptophan in the N-terminal variable domain regulates disulfide bond formation and oligomeric assembly of adiponectin.
The FEBS journal 2012;279(14):2495-507.
2012: Renata Kowalczyk; Maureen Watson; Margaret A Brimble; Karen E Callon; Paul W R Harris; Jillian Cornish
Synthesis and evaluation of disulfide bond mimetics of amylin-(1-8) as agents to treat osteoporosis.
Bioorganic & medicinal chemistry 2012;20(8):2661-8.
2011: Dong Jun Lee; Paul W R Harris; Margaret A Brimble
Synthesis of MUC1 Neoglycopeptides using efficient microwave-enhanced chaotrope-assisted click chemistry.
Organic & biomolecular chemistry 2011;9(5):1621-6.
2011: Kuo-yuan Hung; Paul W R Harris; Amanda M Heapy; Margaret A Brimble
Synthesis and assignment of stereochemistry of the antibacterial cyclic peptide xenematide.
Organic & biomolecular chemistry 2011;9(1):236-42.
2010: Kuo-Yuan Hung; Paul W R Harris; Margaret A Brimble
Synthesis of methyl N-Boc-(2S,4R)-4-methylpipecolate.
The Journal of organic chemistry 2010;75(24):8728-31.
2010: Paul W R Harris; Margaret A Brimble
Toward the total chemical synthesis of the cancer protein NY-ESO-1.
Biopolymers 2010;94(4):542-50.
2009: Dong Jun Lee; Kalyaneswar Mandal; Paul W R Harris; Margaret A Brimble; Stephen B H Kent
A one-pot approach to neoglycopeptides using orthogonal native chemical ligation and click chemistry.
Organic letters 2009;11(22):5270-3.
2008: Margaret A Brimble; Renata Kowalczyk; Paul W R Harris; P Rod Dunbar; Victoria J Muir
Synthesis of fluorescein-labelled O-mannosylated peptides as components for synthetic vaccines: comparison of two synthetic strategies.
Organic & biomolecular chemistry 2008;6(1):112-21.
2006: Paul W R Harris; Margaret A Brimble
Synthesis of macrocyclic analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).
Organic & biomolecular chemistry 2006;4(14):2696-709.
2005: Michelle Y H Lai; Margaret A Brimble; David J Callis; Paul W R Harris; Mark S Levi; Frank Sieg
Synthesis and pharmacological evaluation of glycine-modified analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).
Bioorganic & medicinal chemistry 2005;13(2):533-48.
2005: Margaret A Brimble; Nicholas S Trotter; Paul W R Harris; Frank Sieg
Synthesis and pharmacological evaluation of side chain modified glutamic acid analogues of the neuroprotective agent glycyl-L-prolyl-L-glutamic acid (GPE).
Bioorganic & medicinal chemistry 2005;13(2):519-32.
2005: Nicholas S Trotter; Margaret A Brimble; Paul W R Harris; David J Callis; Frank Sieg
Synthesis and neuroprotective activity of analogues of glycyl-L-prolyl-L-glutamic acid (GPE) modified at the alpha-carboxylic acid.
Bioorganic & medicinal chemistry 2005;13(2):501-17.
2003: Paul W R Harris; Margaret A Brimble; Peter D Gluckman
Synthesis of cyclic proline-containing peptides via ring-closing metathesis.
Organic letters 2003;5(11):1847-50.