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David Hart

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
30
Frank, Cyril
30
Reno, Carol
20
Shrive, Nigel
17
Marchuk, Linda
12
Sciore, Paul
10
Gallant-Behm, Corrie
9
Hellio Le Graverand, Marie-Pierre
9
Hildebrand, Kevin
9
Lo, Ian
9
Olson, Merle
9
Fritzler, Marvin
7
Rattner, Jerome
7
Kydd, Alison
7
Bray, Robert
6
Achari, Yamini

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Publications

TOP 3
Wong Joyce W; Gallant-Behm Corrie; Wiebe Colin; Mak Karen; Hart David A; Larjava Hannu; Häkkinen Lari
Wound healing in oral mucosa results in reduced scar formation as compared with skin: evidence from the red Duroc pig model and humans.
Park Sang-Kyoon; Stefanyshyn Darren J; Ramage Barbara; Hart David A; Ronsky Janet L
Alterations in knee joint laxity during the menstrual cycle in healthy women leads to increases in joint loads during selected athletic movements.
Eslami Ameneh; Gallant-Behm Corrie L; Hart David A; Wiebe Colin; Honardoust Dariush; Gardner Humphrey; Häkkinen Lari; Larjava Hannu S
Expression of integrin alphavbeta6 and TGF-beta in scarless vs scar-forming wound healing.

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All Publications

2009: Wong Joyce W; Gallant-Behm Corrie; Wiebe Colin; Mak Karen; Hart David A; Larjava Hannu; Häkkinen Lari
Wound healing in oral mucosa results in reduced scar formation as compared with skin: evidence from the red Duroc pig model and humans.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2009;17(5):717-29.
2009: Park Sang-Kyoon; Stefanyshyn Darren J; Ramage Barbara; Hart David A; Ronsky Janet L
Alterations in knee joint laxity during the menstrual cycle in healthy women leads to increases in joint loads during selected athletic movements.
The American journal of sports medicine 2009;37(6):1169-77.
2009: Eslami Ameneh; Gallant-Behm Corrie L; Hart David A; Wiebe Colin; Honardoust Dariush; Gardner Humphrey; Häkkinen Lari; Larjava Hannu S
Expression of integrin alphavbeta6 and TGF-beta in scarless vs scar-forming wound healing.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2009;57(6):543-57.
2009: Corr David T; Gallant-Behm Corrie L; Shrive Nigel G; Hart David A
Biomechanical behavior of scar tissue and uninjured skin in a porcine model.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2009;17(2):250-9.
2009: Achari Yamini; Lu Ting; Katzenellenbogen Benita S; Hart David A
Distinct roles for AF-1 and -2 of ER-alpha in regulation of MMP-13 promoter activity.
Biochimica et biophysica acta 2009;1792(3):211-20.
2009: Park Sang-Kyoon; Stefanyshyn Darren J; Loitz-Ramage Barbara; Hart David A; Ronsky Janet L
Changing hormone levels during the menstrual cycle affect knee laxity and stiffness in healthy female subjects.
The American journal of sports medicine 2009;37(3):588-98.
2009: Park S-K; Stefanyshyn D J; Ramage B; Hart D A; Ronsky J L
Relationship between knee joint laxity and knee joint mechanics during the menstrual cycle.
British journal of sports medicine 2009;43(3):174-9.
2008: Parreno Justin; Buckley-Herd Geoff; de-Hemptinne Isabelle; Hart David A
Osteoblastic MG-63 cell differentiation, contraction, and mRNA expression in stress-relaxed 3D collagen I gels.
Molecular and cellular biochemistry 2008;317(1-2):21-32.
2008: Hildebrand Kevin A; Zhang Mei; Salo Paul T; Hart David A
Joint capsule mast cells and neuropeptides are increased within four weeks of injury and remain elevated in chronic stages of posttraumatic contractures.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2008;26(10):1313-9.
2008: Achari Yamini; Lu Ting; Hart David A
Polymorphisms in the promoter regions for human MMP-1 and MMP-13 lead to differential responses to the alpha and beta isoforms of estrogen receptor and their ligand in vitro.
Biochimica et biophysica acta 2008;1782(6):391-400.
2008: Gallant-Behm Corrie L; Hildebrand Kevin A; Hart David A
The mast cell stabilizer ketotifen prevents development of excessive skin wound contraction and fibrosis in red Duroc pigs.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2008;16(2):226-33.
2008: Hildebrand Kevin A; Zhang Mei; Germscheid Niccole M; Wang Chuan; Hart David A
Cellular, matrix, and growth factor components of the joint capsule are modified early in the process of posttraumatic contracture formation in a rabbit model.
Acta orthopaedica 2008;79(1):116-25.
2008: de Hemptinne Isabelle; Gallant-Behm Corrie L; Noack Cassandra L; Parreno Justin; Hart David A
Dermal fibroblasts from red Duroc and Yorkshire pigs exhibit intrinsic differences in the contraction of collagen gels.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2008;16(1):132-42.
2008: Achari Yamini; Reno Carol R; Tsao Helen; Morck Douglas W; Hart David A
Influence of timing (pre-puberty or skeletal maturity) of ovariohysterectomy on mRNA levels in corneal tissues of female rabbits.
Molecular vision 2008;14():443-55.
2007: Myers Kenneth A; Rattner Jerome B; Shrive Nigel G; Hart David A
Osteoblast-like cells and fluid flow: cytoskeleton-dependent shear sensitivity.
Biochemical and biophysical research communications 2007;364(2):214-9.
2007: Berglund M; Hart D A; Wiig M
The inflammatory response and hyaluronan synthases in the rabbit flexor tendon and tendon sheath following injury.
The Journal of hand surgery, European volume 2007;32(5):581-7.
2007: Myers Kenneth A; Rattner Jerome B; Shrive Nigel G; Hart David A
Hydrostatic pressure sensation in cells: integration into the tensegrity model.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2007;85(5):543-51.
2007: Funakoshi Yusei; Hariu Mitsuhiro; Tapper Janet E; Marchuk Linda L; Shrive Nigel G; Kanaya Fuminori; Rattner Jerome B; Hart David A; Frank Cyril B
Periarticular ligament changes following ACL/MCL transection in an ovine stifle joint model of osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2007;25(8):997-1006.
2007: Salo Paul; Bray Robert; Seerattan Ruth; Reno Carol; McDougall Jason; Hart David A
Neuropeptides regulate expression of matrix molecule, growth factor and inflammatory mediator mRNA in explants of normal and healing medial collateral ligament.
Regulatory peptides 2007;142(1-2):1-6.
2007: Myers Kenneth A; Shrive Nigel G; Hart David A
A novel apparatus applying long term intermittent cyclic hydrostatic pressure to in vitro cell cultures.
Journal of bioscience and bioengineering 2007;103(6):578-81.
2007: Lu Ting; Achari Yamini; Rattner Jerome B; Hart David A
Evidence that estrogen receptor beta enhances MMP-13 promoter activity in HIG-82 cells and that this enhancement can be influenced by ligands and involves specific promoter sites.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2007;85(3):326-36.
2007: Kydd Alison S; Reno Carol R; Tsao Helen W; Hart David A
Impact of age, systemic glucocorticoids, and progressive knee arthritis on specific mRNA levels in different areas of the rabbit cornea.
Cornea 2007;26(3):352-61.
2007: Hildebrand Kevin A; Zhang Mei; Hart David A
Myofibroblast upregulators are elevated in joint capsules in posttraumatic contractures.
Clinical orthopaedics and related research 2007;456():85-91.
2007: Miller Daniel; Forrester Kevin; Hart David A; Leonard Catherine; Salo Paul; Bray Robert C
Endothelial dysfunction and decreased vascular responsiveness in the anterior cruciate ligament-deficient model of osteoarthritis.
Journal of applied physiology (Bethesda, Md. : 1985) 2007;102(3):1161-9.
2007: Kydd Alison S; Reno Carol R; Tsao Helen W; Hart David A
Early inflammatory arthritis in the rabbit: the influence of intraarticular and systemic corticosteroids on mRNA levels in connective tissues of the knee.
The Journal of rheumatology 2007;34(1):130-9.
2007: Gallant-Behm Corrie L; Reno Carol; Tsao Helen; Hart David A
Genetic involvement in skin wound healing and scarring in domestic pigs: assessment of molecular expression patterns in (Yorkshire x Red Duroc) x Yorkshire backcross animals.
The Journal of investigative dermatology 2007;127(1):233-44.
2006: Stewart C J; Gallant-Behm C L; Forrester K; Tulip J; Hart D A; Bray R C
Kinetics of blood flow during healing of excisional full-thickness skin wounds in pigs as monitored by laser speckle perfusion imaging.
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 2006;12(4):247-53.
2006: Berglund Maria; Reno Carol; Hart David A; Wiig Monica
Patterns of mRNA expression for matrix molecules and growth factors in flexor tendon injury: differences in the regulation between tendon and tendon sheath.
The Journal of hand surgery 2006;31(8):1279-87.
2006: Beye Jasmine A; Hart David A; Bray Robert C; Seerattan Ruth A; McDougall Jason J; Leonard Catherine A; Reno Carol R; Salo Paul T
Denervation alters mRNA levels of repair-associated genes in a rabbit medial collateral ligament injury model.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2006;24(9):1842-53.
2006: Lu Ting; Achari Yamini; Sciore Paul; Hart D A
Estrogen receptor alpha regulates matrix metalloproteinase-13 promoter activity primarily through the AP-1 transcriptional regulatory site.
Biochimica et biophysica acta 2006;1762(8):719-31.
2006: Hildebrand Kevin A; Zhang Mei; Hart David A
Joint capsule matrix turnover in a rabbit model of chronic joint contractures: Correlation with human contractures.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2006;24(5):1036-43.
2006: Gallant-Behm C L; Tsao H; Reno C; Olson M E; Hart D A
Skin wound healing in the first generation (F1) offspring of Yorkshire and red Duroc pigs: evidence for genetic inheritance of wound phenotype.
Burns : journal of the International Society for Burn Injuries 2006;32(2):180-93.
2006: Gallant-Behm Corrie L; Hart David A
Genetic analysis of skin wound healing and scarring in a porcine model.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2006;14(1):46-54.
2005: Hildebrand Kevin A; Zhang Mei; Hart David A
High rate of joint capsule matrix turnover in chronic human elbow contractures.
Clinical orthopaedics and related research 2005;439():228-34.
2005: Kydd Alison S; Achari Yamini; Lu Ting; Sciore Paul; Rattner J B; Hart David A
The healing rabbit medial collateral ligament of the knee responds to systemically administered glucocorticoids differently than the uninjured tissues of the same joint or the uninjured MCL: a paradoxical shift in impact on specific mRNA levels and MMP-13 protein expression in injured tissues.
Biochimica et biophysica acta 2005;1741(3):289-99.
2005: Gallant-Behm Corrie L; Olson Merle E; Hart David A
Cytokine and growth factor mRNA expression patterns associated with the hypercontracted, hyperpigmented healing phenotype of red duroc pigs: a model of abnormal human scar development?
Journal of cutaneous medicine and surgery 2005;9(4):165-77.
2005: Gallant-Behm Corrie L; Yin Hua Q; Liu Shijie; Heggers John P; Langford Rita E; Olson Merle E; Hart David A; Burrell Robert E
Comparison of in vitro disc diffusion and time kill-kinetic assays for the evaluation of antimicrobial wound dressing efficacy.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2005;13(4):412-21.
2005: Lo Ian K Y; Boorman Richard; Marchuk Linda; Hollinshead Robert; Hart David A; Frank Cyril B
Matrix molecule mRNA levels in the bursa and rotator cuff of patients with full-thickness rotator cuff tears.
Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 2005;21(6):645-51.
2005: Tasevski V; Sorbetti J M; Chiu S S; Shrive N G; Hart D A
Influence of mechanical and biological signals on gene expression in human MG-63 cells: evidence for a complex interplay between hydrostatic compression and vitamin D3 or TGF-beta1 on MMP-1 and MMP-3 mRNA levels.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2005;83(1):96-107.
2005: Kydd Alison S; Reno Carol; Sorbetti Jovina M; Hart David A
Influence of a single systemic corticosteroid injection on mRNA levels for a subset of genes in connective tissues of the rabbit knee: a comparison of steroid types and effect of skeletal maturity.
The Journal of rheumatology 2005;32(2):307-19.
2004: Schoenroth Leeanne J; Hart David A; Pollard K Michael; Fritzler Marvin J
The effect of the phytoestrogen coumestrol on the NZB/W F1 murine model of systemic lupus.
Journal of autoimmunity 2004;23(4):323-32.
2004: Lo Ian K Y; Marchuk Linda L; Hollinshead Robert; Hart David A; Frank Cyril B
Matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase mRNA levels are specifically altered in torn rotator cuff tendons.
The American journal of sports medicine 2004;32(5):1223-9.
2004: Adeeb Samer M; Sayed Ahmed Ezzeldin Y; Matyas John; Hart David A; Frank Cyril B; Shrive Nigel G
Congruency effects on load bearing in diarthrodial joints.
Computer methods in biomechanics and biomedical engineering 2004;7(3):147-57.
2004: Gallant Corrie L; Olson Merle E; Hart David A
Molecular, histologic, and gross phenotype of skin wound healing in red Duroc pigs reveals an abnormal healing phenotype of hypercontracted, hyperpigmented scarring.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2004;12(3):305-19.
2004: Hart David A; Kydd Alison S; Frank Cyril B; Hildebrand Kevin A
Tissue repair in rheumatoid arthritis: challenges and opportunities in the face of a systemic inflammatory disease.
Best practice & research. Clinical rheumatology 2004;18(2):187-202.
2004: Berglund M; Wiig M; Torstensson M; Reno C; Hart D A
Assessment of mRNA levels for matrix molecules and TGF- beta1 in rabbit flexor and peroneus tendons reveals regional differences in steady-state expression.
Journal of hand surgery (Edinburgh, Scotland) 2004;29(2):165-9.
2004: Frank C B; Shrive N G; Boorman R S; Lo I K Y; Hart D A
New perspectives on bioengineering of joint tissues: joint adaptation creates a moving target for engineering replacement tissues.
Annals of biomedical engineering 2004;32(3):458-65.
2004: Wang Jian Fei; Olson Merle E; Ma Lingling; Brigstock David R; Hart David A
Connective tissue growth factor siRNA modulates mRNA levels for a subset of molecules in normal and TGF-beta 1-stimulated porcine skin fibroblasts.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2004;12(2):205-16.
2004: Hildebrand Kevin A; Zhang Mei; van Snellenberg Wistara; King Graham J W; Hart David A
Myofibroblast numbers are elevated in human elbow capsules after trauma.
Clinical orthopaedics and related research 2004;(419):189-97.
2004: Hildebrand K A; Frank C B; Hart D A
Gene intervention in ligament and tendon: current status, challenges, future directions.
Gene therapy 2004;11(4):368-78.
2004: Lo Ian K Y; Marchuk Linda L; Leatherbarrow Kate E; Frank Cyril B; Hart David A
Collagen fibrillogenesis and mRNA levels in the maturing rabbit medial collateral ligament and patellar tendon.
Connective tissue research 2004;45(1):11-22.
2003: Doschak M R; Cooper D M L; Huculak C N; Matyas J R; Hart D A; Hallgrimsson B; Zernicke R F; Bray R C
Angiogenesis in the distal femoral chondroepiphysis of the rabbit during development of the secondary centre of ossification.
Journal of anatomy 2003;203(2):223-33.
2003: Wang Jian Fei; Olson Merle E; Ball Deanna K; Brigstock David R; Hart David A
Recombinant connective tissue growth factor modulates porcine skin fibroblast gene expression.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2003;11(3):220-9.
2003: Meakin Judith R; Shrive Nigel G; Frank Cyril B; Hart David A
Finite element analysis of the meniscus: the influence of geometry and material properties on its behaviour.
The Knee 2003;10(1):33-41.
2003: Lo Ian K Y; Marchuk Linda; Hart David A; Frank Cyril B
Messenger ribonucleic acid levels in disrupted human anterior cruciate ligaments.
Clinical orthopaedics and related research 2003;(407):249-58.
2003: Lo Ian K Y; Marchuk Linda; Majima Tokifumi; Frank Cyril B; Hart David A
Medial collateral ligament and partial anterior cruciate ligament transection: mRNA changes in uninjured ligaments of the sheep knee.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2003;8(5):707-13.
2002: Hildebrand Kevin A; Hiraoka Histada; Hart David A; Shrive Nigel G; Frank Cyril B
Exogenous transforming growth factor beta 1 alone does not improve early healing of medial collateral ligament in rabbits.
Canadian journal of surgery. Journal canadien de chirurgie 2002;45(5):330-6.
2002: Wang Jian Fei; Olson Merle E; Winkfein Robert J; Kulyk William M; Wright J Barry; Hart David A
Molecular and cell biology of porcine HSP47 during wound healing: complete cDNA sequence and regulation of gene expression.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2002;10(4):230-40.
2002: Le Graverand Marie-Pierre Hellio; Eggerer Jonna; Vignon Eric; Otterness Ivan G; Barclay Leona; Hart David A
Assessment of specific mRNA levels in cartilage regions in a lapine model of osteoarthritis.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2002;20(3):535-44.
2002: Majima Tokifumi; Lo Ian K Y; Randle John A; Marchuk Linda L; Shrive Nigel G; Frank Cyril B; Hart David A
ACL transection influences mRNA levels for collagen type I and TNF-alpha in MCL scar.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2002;20(3):520-5.
2002: Lo Ian K Y; Ou Yong; Rattner John-Paul; Hart David A; Marchuk Linda L; Frank Cyril B; Rattner Jerome B
The cellular networks of normal ovine medial collateral and anterior cruciate ligaments are not accurately recapitulated in scar tissue.
Journal of anatomy 2002;200(Pt 3):283-96.
2001: Wang J F; Olson M E; Reno C R; Wright J B; Hart D A
The pig as a model for excisional skin wound healing: characterization of the molecular and cellular biology, and bacteriology of the healing process.
Comparative medicine 2001;51(4):341-8.
2001: Hellio Le Graverand M P; Sciore P; Eggerer J; Rattner J P; Vignon E; Barclay L; Hart D A; Rattner J B
Formation and phenotype of cell clusters in osteoarthritic meniscus.
Arthritis and rheumatism 2001;44(8):1808-18.
2001: Doschak M R; Matyas J R; Hart D A; Bray R C
Vascular alterations in the rabbit patellar tendon after surgical incision.
Journal of anatomy 2001;198(Pt 5):513-23.
2001: Nakamura N; Hart D A; Frank C B; Marchuk L L; Shrive N G; Ota N; Taira K; Yoshikawa H; Kaneda Y
Efficient transfer of intact oligonucleotides into the nucleus of ligament scar fibroblasts by HVJ-cationic liposomes is correlated with effective antisense gene inhibition.
Journal of biochemistry 2001;129(5):755-9.
2001: Hellio Le Graverand M P; Vignon E; Otterness I G; Hart D A
Early changes in lapine menisci during osteoarthritis development: Part II: molecular alterations.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(1):65-72.
2001: Hellio Le Graverand M P; Vignon E; Otterness I G; Hart D A
Early changes in lapine menisci during osteoarthritis development: Part I: cellular and matrix alterations.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2001;9(1):56-64.
2001: Archambault J M; Hart D A; Herzog W
Response of rabbit Achilles tendon to chronic repetitive loading.
Connective tissue research 2001;42(1):13-23.
2000: Hart D A; Evans C H
Orthopaedic gene therapy. Ligament and tendon.
Clinical orthopaedics and related research 2000;(379 Suppl):S260-1.
2000: Hart D A; Nakamura N; Marchuk L; Hiraoka H; Boorman R; Kaneda Y; Shrive N G; Frank C B
Complexity of determining cause and effect in vivo after antisense gene therapy.
Clinical orthopaedics and related research 2000;(379 Suppl):S242-51.
2000: Hellio Le Graverand M P; Eggerer J; Sciore P; Reno C; Vignon E; Otterness I; Hart D A
Matrix metalloproteinase-13 expression in rabbit knee joint connective tissues: influence of maturation and response to injury.
Matrix biology : journal of the International Society for Matrix Biology 2000;19(5):431-41.
2000: Majima T; Marchuk L L; Sciore P; Shrive N G; Frank C B; Hart D A
Compressive compared with tensile loading of medial collateral ligament scar in vitro uniquely influences mRNA levels for aggrecan, collagen type II, and collagenase.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2000;18(4):524-31.
2000: Nakamura N; Hart D A; Boorman R S; Kaneda Y; Shrive N G; Marchuk L L; Shino K; Ochi T; Frank C B
Decorin antisense gene therapy improves functional healing of early rabbit ligament scar with enhanced collagen fibrillogenesis in vivo.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2000;18(4):517-23.
2000: McDougall J J; Bray R C; Hart D A
Late gestational changes in sympathomimetic sensitivity in primagravid rabbit ligaments.
Canadian journal of physiology and pharmacology 2000;78(7):528-34.
2000: Hart D A; Reno C; Frank C B; Shrive N G
Pregnancy affects cellular activity, but not tissue mechanical properties, in the healing rabbit medial collateral ligament.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2000;18(3):462-71.
2000: Belik J; Karpinka B; Hart D A
Pulmonary and systemic vascular tissue collagen, growth factor, and cytokine gene expression in the rabbit.
Canadian journal of physiology and pharmacology 2000;78(5):400-6.
2000: Hellio Le Graverand M P; Reno C; Hart D A
Heterogenous response of knee cartilage to pregnancy in the rabbit: assessment of specific mRNA levels.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2000;8(1):53-62.
2000: Wang J F; Olson M E; Reno C R; Kulyk W; Wright J B; Hart D A
Molecular and cell biology of skin wound healing in a pig model.
Connective tissue research 2000;41(3):195-211.
2000: Majima T; Marchuk L L; Shrive N G; Frank C B; Hart D A
In-vitro cyclic tensile loading of an immobilized and mobilized ligament autograft selectively inhibits mRNA levels for collagenase (MMP-1).
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 2000;5(5):503-10.
2000: Hart D A; Reno C; Hellio Le Graverand M P; Hoffman L; Kulyk W
Expression of heat shock protein 47(Hsp47) mRNA levels in rabbit connective tissues during the response to injury and in pregnancy.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2000;78(4):511-8.
1999: Hellio Le Graverand M P; Reno C; Hart D A
Gene expression in menisci from the knees of skeletally immature and mature female rabbits.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1999;17(5):738-44.
1999: Hart D A; Kydd A; Reno C
Gender and pregnancy affect neuropeptide responses of the rabbit Achilles tendon.
Clinical orthopaedics and related research 1999;(365):237-46.
1999: Hart D A; Reno C
Pregnancy alters gene expression in normal synovium: influence of age and parity.
The Journal of rheumatology 1999;26(8):1775-84.
1999: Frank C B; Hart D A; Shrive N G
Molecular biology and biomechanics of normal and healing ligaments--a review.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1999;7(1):130-40.
1999: Cunningham K D; Musani F; Hart D A; Shrive N G; Frank C B
Collagenase degradation decreases collagen fibril diameters--an in vitro study of the rabbit medial collateral ligament.
Connective tissue research 1999;40(1):67-74.
1999: Hellio Le Graverand M P; Reno C; Hart D A
Gene expression in rabbit menisci during pregnancy.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1999;77(3):215-22.
1998: Nakamura N; Timmermann S A; Hart D A; Kaneda Y; Shrive N G; Shino K; Ochi T; Frank C B
A comparison of in vivo gene delivery methods for antisense therapy in ligament healing.
Gene therapy 1998;5(11):1455-61.
1998: Reno C; Boykiw R; Martinez M L; Hart D A
Temporal alterations in mRNA levels for proteinases and inhibitors and their potential regulators in the healing medial collateral ligament.
Biochemical and biophysical research communications 1998;252(3):757-63.
1998: Boykiw R; Sciore P; Reno C; Marchuk L; Frank C B; Hart D A
Altered levels of extracellular matrix molecule mRNA in healing rabbit ligaments.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(5):371-8.
1998: Hart D A; Reno C
Pregnancy alters the in vitro responsiveness of the rabbit medial collateral ligament to neuropeptides: effect on mRNA levels for growth factors, cytokines, iNOS, COX-2, metalloproteinases and TIMPs.
Biochimica et biophysica acta 1998;1408(1):35-43.
1998: McDougall J J; Giles R W; Bray R C; Hart D A
Pregnancy-induced changes in rabbit medial collateral ligament vasoregulation.
The American journal of physiology 1998;275(4 Pt 2):R1380-5.
1998: Hellio Le Graverand M P; Reno C; Hart D A
Influence of pregnancy on gene expression in rabbit articular cartilage.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(5):341-50.
1998: Sciore P; Frank C B; Hart D A
Identification of sex hormone receptors in human and rabbit ligaments of the knee by reverse transcription-polymerase chain reaction: evidence that receptors are present in tissue from both male and female subjects.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1998;16(5):604-10.
1998: Sciore P; Boykiw R; Hart D A
Semiquantitative reverse transcription-polymerase chain reaction analysis of mRNA for growth factors and growth factor receptors from normal and healing rabbit medial collateral ligament tissue.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1998;16(4):429-37.
1998: Lo I K; Marchuk L L; Hart D A; Frank C B
Comparison of mRNA levels for matrix molecules in normal and disrupted human anterior cruciate ligaments using reverse transcription-polymerase chain reaction.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1998;16(4):421-8.
1998: Hart D A; Archambault J M; Kydd A; Reno C; Frank C B; Herzog W
Gender and neurogenic variables in tendon biology and repetitive motion disorders.
Clinical orthopaedics and related research 1998;(351):44-56.
1998: Hart D A; Boykiw R; Sciore P; Reno C
Complex alterations in gene expression occur in the knee ligaments of the skeletally mature multiparous rabbit during pregnancy.
Biochimica et biophysica acta 1998;1397(3):331-41.
1998: Hart D A; Sciore P; Boykiw R; Reno C
Pregnancy induces complex changes in the the pattern of mRNA expression in knee ligaments of the adolescent rabbit.
Matrix biology : journal of the International Society for Matrix Biology 1998;17(1):21-34.
1998: Marchuk L; Sciore P; Reno C; Frank C B; Hart D A
Postmortem stability of total RNA isolated from rabbit ligament, tendon and cartilage.
Biochimica et biophysica acta 1998;1379(2):171-7.
1998: Veillette C J; Cunningham K D; Hart D A; Fritzler M J; Frank C B
Localization and characterization of porcine patellar tendon xenograft antigens in a rabbit model of medial collateral ligament replacement.
Transplantation 1998;65(4):486-93.
1997: Reno C; Marchuk L; Sciore P; Frank C B; Hart D A
Rapid isolation of total RNA from small samples of hypocellular, dense connective tissues.
BioTechniques 1997;22(6):1082-6.
1996: Hart D A; Louie T; Krulicki W; Reno C
Staphylococcus aureus strains differ in their in vitro responsiveness to human urokinase: evidence that methicillin-resistant strains are predominately nonresponsive to the growth-enhancing effects of urokinase.
Canadian journal of microbiology 1996;42(10):1024-31.
1995: Wilson D; Edworthy S M; Hart D A; Fritzler M J
The safety and efficacy of low-dose tissue plasminogen activator in the treatment of systemic sclerosis.
The Journal of dermatology 1995;22(9):637-42.
1995: Fritzler M J; Hart D A; Wilson D; García-De La Torre I; Salazar-Páramo M; Vázquez-Del Mercado M; Senécal J L; Loyau S; Anglés-Cano E
Antibodies to fibrin bound tissue type plasminogen activator in systemic sclerosis.
The Journal of rheumatology 1995;22(9):1688-93.
1995: Lenz S P; Izui S; Benediktsson H; Hart D A
Lithium chloride enhances survival of NZB/W lupus mice: influence of melatonin and timing of treatment.
International journal of immunopharmacology 1995;17(7):581-92.
1994: Hart D A; Done S J; Benediktsson H; Lenz S P
Partial characterization of the enhanced survival of female NZB/W mice treated with lithium chloride.
International journal of immunopharmacology 1994;16(10):825-33.
1994: Murphy P G; Loitz B J; Frank C B; Hart D A
Influence of exogenous growth factors on the synthesis and secretion of collagen types I and III by explants of normal and healing rabbit ligaments.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1994;72(9-10):403-9.
1994: Murphy P G; Hart D A
Influence of exogenous growth factors on the expression of plasminogen activators and plasminogen activator inhibitors by cells isolated from normal and healing rabbit ligaments.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1994;12(4):564-75.
1994: Hart D A; Woods D E
Urokinase enhances the growth of Pseudomonas spp. in vitro under nonshaking (oxygen limited) conditions.
Canadian journal of microbiology 1994;40(4):292-7.
1994: Hart D A; Whidden P; Green F; Henkin J; Woods D E
Partial reversal of established bleomycin-induced pulmonary fibrosis by rh-urokinase in a rat model.
Clinical and investigative medicine. Médecine clinique et experimentale 1994;17(2):69-76.
1993: Hart D A; Green F; Whidden P; Henkin J; Woods D E
Exogenous rh-urokinase modifies inflammation and Pseudomonas aeruginosa infection in a rat chronic pulmonary infection model.
Canadian journal of microbiology 1993;39(12):1127-34.
1993: Murphy P G; Loitz B J; Frank C B; Hart D A
Influence of exogenous growth factors on the expression of plasminogen activators by explants of normal and healing rabbit ligaments.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1993;71(11-12):522-9.
1993: Murphy P G; Hart D A
Plasminogen activators and plasminogen activator inhibitors in connective tissues and connective tissue cells: influence of the neuropeptide substance P on expression.
Biochimica et biophysica acta 1993;1182(2):205-14.
1993: Murphy P G; Lenz S P; Dobson M; Arndt A D; Hart D A
Purification and characterization of the plasminogen activator inhibitors PAI-1, PAI-2, and PN-1 from the human glioblastoma U138.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1993;71(5-6):248-54.
1993: Murphy P G; Frank C B; Hart D A
Characterization of the plasminogen activators and plasminogen activator inhibitors expressed by cells isolated from rabbit ligament and synovial tissues: evidence for unique cell populations.
Experimental cell research 1993;205(1):16-24.
1993: Lenz S P; Green F H; Murphy P G; Lee M; Hart D A
Expression of plasminogen activator and plasminogen activator inhibitor by rat mesothelioma induced by asbestos.
Cancer letters 1993;68(2-3):119-27.
1992: Arndt A; Murphy P; Hart D A
Human HuH-7 hepatoma cells express urokinase and plasminogen activator inhibitor-1: identification, characterization and regulation by inflammatory mediators.
Biochimica et biophysica acta 1992;1138(2):149-56.
1992: Murphy P; Hart D A
Modulation of plasminogen activator and plasminogen activator inhibitor expression in the human U373 glioblastoma/astrocytoma cell line by inflammatory mediators.
Experimental cell research 1992;198(1):93-100.
1992: Krause G; Martin L; Fritzler M; Hart D A
Influence of Corynebacterium parvum-PER on disease progression in the NZB/W model of systemic lupus erythematosus.
International journal of immunopharmacology 1992;14(1):35-41.
1991: Murphy P G; Hart D A
Regulation of plasminogen activator and plasminogen activator inhibitor expression by cells of neural origin.
Seminars in thrombosis and hemostasis 1991;17(3):268-75.
1991: Hart D A; Krause G; Martin L; Garlepp M; Fritzler M J
Influence of biological response modifiers of bacterial origin on disease progression in the MRL-lpr model of systemic lupus erythematosus.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(1):55-62.
1990: Rehemtulla A; Arndt A; Hart D A
Induction of plasminogen activator inhibitor type 2 expression during differentiation of human K562 cells towards a macrophage phenotype.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1990;68(12):1337-43.
1989: Arndt A D; Gohill J; Rankin K; Houwen B; Hart D A
Differentiation-linked expression of the plasminogen activator inhibitor type-2 gene in the human HL-60 promyelocytic cell line.
Experimental cell research 1989;185(2):473-81.
1989: Hart D A; Garlepp M; Fritzler M
Plasma proteinase regulation during disease progression in murine models of SLE.
Journal of clinical & laboratory immunology 1989;30(1):27-34.
1989: Hart D A; Fritzler M J
Regulation of plasminogen activators and their inhibitors in rheumatic diseases: new understanding and the potential for new directions.
The Journal of rheumatology 1989;16(9):1184-91.
1989: Garlepp M J; Hart D A; Fritzler M J
Regulation of plasma complement C4 and factor b levels in murine systemic lupus erythematosus.
Journal of clinical & laboratory immunology 1989;28(3):137-41.
1989: Benjamin L A; McGarry R C; Hart D A
Alterations in plasminogen activator and inhibitor activity during the differentiation of a human neuroblastoma cell line, SMS-KAN.
Cancer letters 1989;44(2):101-8.
1989: Benjamin L A; McGarry R C; Hart D A
Effect of retinoic acid on human neuroblastoma: correlation between morphological differentiation and changes in plasminogen activator and inhibitor activity.
Cancer chemotherapy and pharmacology 1989;25(1):25-31.
1988: Rehemtulla A; Murphy P; Dobson M; Hart D A
Purification and partial characterization of a plasminogen activator inhibitor from the human glioblastoma, U138.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1988;66(12):1270-7.
1988: Garlepp M J; Fritzler M J; Hart D A
Differential effect of inflammatory stimuli on murine plasma C4 and factor B concentrations.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(5):341-6.
1988: Hart D A
Age and lpr dependent induction of increased sensitivity to the toxic effects of lipopolysaccharide and indomethacin in MRL mice: evidence for RES activation during disease progression.
Journal of clinical & laboratory immunology 1988;26(3):129-34.
1988: Hart D A
Differences between beige and bg/+ mice in the disruption of plasma proteinase regulation in the tumor-bearing state or following Corynebacterium parvum treatment. Evidence for the involvement of polymorphonuclear leukocyte proteinases.
Haemostasis 1988;18(3):154-62.
1988: Hart D A; Rehemtulla A
Plasminogen activators and their inhibitors: regulators of extracellular proteolysis and cell function.
Comparative biochemistry and physiology. B, Comparative biochemistry 1988;90(4):691-708.
1988: Hart D A
Lithium potentiates antigen-dependent stimulation of lymphocytes only under suboptimal conditions.
International journal of immunopharmacology 1988;10(2):153-60.
1987: Murphy P; Hart D A
Regulation of enzyme release from human polymorphonuclear leukocytes: further evidence for the independent regulation of granule subpopulations.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1987;65(12):1007-15.
1987: Hart D A
Steroids and tuftsin fail to prevent the induction of altered plasma proteinase homeostasis in mice bearing the B16 melanoma or treated with C. parvum.
International journal of immunopharmacology 1987;9(6):669-74.
1987: Rehemtulla A; Gates J; Hart D A
Treatment of mouse L-cells with phorbol myristate acetate induces the secretion of a plasminogen activator inhibitor which binds to human and mouse urokinase and human tissue plasminogen activator.
Comparative biochemistry and physiology. B, Comparative biochemistry 1987;88(1):277-83.

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