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Roland Hartig

Research Profile

Anatomy

Living Beings

Helicobacter pylori

Procedures

Chemicals & Drugs

Physiology

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Publications

TOP 3
Anja Stirnweiss; Hannes Stockinger; Werner Zuschratter; Luca Simeoni; Steffi Gieseler; Matthias Gunzer; Thomas Harder; Roland Hartig; Jonathan A Lindquist; Camilla Merten; Wolfgang Paster; Lars Philipsen; Mateusz Poltorak; Yury Prokazov; Peter Reichardt; Burkhart Schraven
T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.
Nadine Andrae; Daniela Haase; Roland Hartig; Thomas Kalinski; Gerburg Keilhoff; Elmar Kirches; Christian Mawrin
Sunitinib targets PDGF-receptor and Flt3 and reduces survival and migration of human meningioma cells.
K Bajbouj; Roland Hartig; Christian Mawrin; A Roessner; J Schulze-Luehrmann; A Wilisch-Neumann; R Schneider-Stock
P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.

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All Publications

2013: Anja Stirnweiss; Hannes Stockinger; Werner Zuschratter; Luca Simeoni; Steffi Gieseler; Matthias Gunzer; Thomas Harder; Roland Hartig; Jonathan A Lindquist; Camilla Merten; Wolfgang Paster; Lars Philipsen; Mateusz Poltorak; Yury Prokazov; Peter Reichardt; Burkhart Schraven
T cell activation results in conformational changes in the Src family kinase Lck to induce its activation.
Science signaling 2013;6(263):ra13.
2012: Nadine Andrae; Daniela Haase; Roland Hartig; Thomas Kalinski; Gerburg Keilhoff; Elmar Kirches; Christian Mawrin
Sunitinib targets PDGF-receptor and Flt3 and reduces survival and migration of human meningioma cells.
European journal of cancer (Oxford, England : 1990) 2012;48(12):1831-41.
2012: K Bajbouj; Roland Hartig; Christian Mawrin; A Roessner; J Schulze-Luehrmann; A Wilisch-Neumann; R Schneider-Stock
P53-dependent antiproliferative and pro-apoptotic effects of trichostatin A (TSA) in glioblastoma cells.
Journal of neuro-oncology 2012;107(3):503-16.
2011: Constanze Nossol; A Post; Hermann-Josef Rothkötter; N Walk; A-K Diesing; Heidrun Faber-Zuschratter; Roland Hartig; J Kluess; Stefan Kahlert
Air-liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC).
Histochemistry and cell biology 2011;136(1):103-15.
2011: Angela Poehlmann; Kathrin Reissig; Albert Roessner; Khuloud Bajbouj; Antje Diestel; Hala Gali-Muhtasib; Caroline Habold; Roland Hartig; Oliver Ullrich; Diana Walluscheck; Regine Schneider-Stock
Cutting edge: Chk1 directs senescence and mitotic catastrophe in recovery from G₂ checkpoint arrest.
Journal of cellular and molecular medicine 2011;15(7):1528-41.
2011: Nicole Tegtmeyer; Silja Wessler; Ruth Wittelsberger; Roland Hartig; Narcisa Martinez-Quiles; Steffen Backert
Serine phosphorylation of cortactin controls focal adhesion kinase activity and cell scattering induced by Helicobacter pylori.
Cell host & microbe 2011;9(6):520-31.
2010: Diane Bimczok; Frank Verdonck; Roland Hartig; Eric Cox; Hermann-Josef Rothkötter
Primary porcine CD11R1+ antigen-presenting cells isolated from small intestinal mucosa mature but lose their T cell stimulatory function in response to cholera toxin treatment.
Veterinary immunology and immunopathology 2010;134(3-4):239-48.
2009: Sabine Brandt; Silja Wessler; Roland Hartig; Steffen Backert
Helicobacter pylori activates protein kinase C delta to control Raf in MAP kinase signalling: role in AGS epithelial cell scattering and elongation.
Cell motility and the cytoskeleton 2009;66(10):874-92.
2009: Nicole Tegtmeyer; Dana Zabler; Diana Schmidt; Roland Hartig; Sabine Brandt; Steffen Backert
Importance of EGF receptor, HER2/Neu and Erk1/2 kinase signalling for host cell elongation and scattering induced by the Helicobacter pylori CagA protein: antagonistic effects of the vacuolating cytotoxin VacA.
Cellular microbiology 2009;11(3):488-505.
2008: Elena Sokolova; Roland Hartig; Georg Reiser
Downregulation of protease-activated receptor-1 in human lung fibroblasts is specifically mediated by the prostaglandin E receptor EP2 through cAMP elevation and protein kinase A.
The FEBS journal 2008;275(14):3669-79.
2008: Anita Posevitz-Fejfár; Michal Smída; Stefanie Kliche; Roland Hartig; Burkhart Schraven; Jonathan A Lindquist
A displaced PAG enhances proximal signaling and SDF-1-induced T cell migration.
European journal of immunology 2008;38(1):250-9.
2007: Terry Kwok; Dana Zabler; Sylwia Urman; Manfred Rohde; Roland Hartig; Silja Wessler; Rolf Misselwitz; Jürgen Berger; Norbert Sewald; Wolfgang König; Steffen Backert
Helicobacter exploits integrin for type IV secretion and kinase activation.
Nature 2007;449(7164):862-6.
2007: Malgorzata Krause-Gruszczynska; Manfred Rohde; Roland Hartig; Harald Genth; Gudula Schmidt; Thormika Keo; Wolfgang König; William G Miller; Michael E Konkel; Steffen Backert
Role of the small Rho GTPases Rac1 and Cdc42 in host cell invasion of Campylobacter jejuni.
Cellular microbiology 2007;9(10):2431-44.
2007: Sabine Brandt; Sasha Shafikhani; Priya Balachandran; Shouguang Jin; Roland Hartig; Wolfgang König; Joanne Engel; Steffen Backert
Use of a novel coinfection system reveals a role for Rac1, H-Ras, and CrkII phosphorylation in Helicobacter pylori-induced host cell actin cytoskeletal rearrangements.
FEMS immunology and medical microbiology 2007;50(2):190-205.
2007: Anja Thielitz; Dirk Reinhold; Robert Vetter; Ute Bank; Martin Helmuth; Roland Hartig; Sabine Wrenger; Ingrid Wiswedel; Uwe Lendeckel; Thilo Kähne; Klaus Neubert; Jürgen Faust; Christos Zouboulis; Siegfried Ansorge; Harald Gollnick
Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.
The Journal of investigative dermatology 2007;127(5):1042-51.
2007: Ina Tammer; Sabine Brandt; Roland Hartig; Wolfgang König; Steffen Backert
Activation of Abl by Helicobacter pylori: a novel kinase for CagA and crucial mediator of host cell scattering.
Gastroenterology 2007;132(4):1309-19.
2007: Doerthe Kuester; Altaf A Dar; Christopher C Moskaluk; Sabine Krueger; Frank Meyer; Roland Hartig; Manfred Stolte; Peter Malfertheiner; Hans Lippert; Albert Roessner; Wa'el El-Rifai; Regine Schneider-Stock
Early involvement of death-associated protein kinase promoter hypermethylation in the carcinogenesis of Barrett's esophageal adenocarcinoma and its association with clinical progression.
Neoplasia (New York, N.Y.) 2007;9(3):236-45.
2007: Uwe Dürer; Roland Hartig; Susanne Bang; Lars Thim; Werner Hoffmann
TFF3 and EGF induce different migration patterns of intestinal epithelial cells in vitro and trigger increased internalization of E-cadherin.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2007;20(5):329-46.
2006: Sabine Wrenger; Jürgen Faust; Daniel Friedrich; Torsten Hoffmann; Roland Hartig; Uwe Lendeckel; Thilo Kähne; Anja Thielitz; Klaus Neubert; Dirk Reinhold
Attractin, a dipeptidyl peptidase IV/CD26-like enzyme, is expressed on human peripheral blood monocytes and potentially influences monocyte function.
Journal of leukocyte biology 2006;80(3):621-9.
2006: Rainer Schäfer; Roland Hartig; Fariba Sedehizade; Tobias Welte; Georg Reiser
Adenine nucleotides inhibit proliferation of the human lung adenocarcinoma cell line LXF-289 by activation of nuclear factor kappaB1 and mitogen-activated protein kinase pathways.
The FEBS journal 2006;273(16):3756-67.
2006: Regine Schneider-Stock; Doerthe Kuester; O Ullrich; F Mittag; C Habold; Carsten Boltze; Brigitte Peters; Sabine Krueger; C Hintze; Frank Meyer; Roland Hartig; Albert Roessner
Close localization of DAP-kinase positive tumour-associated macrophages and apoptotic colorectal cancer cells.
The Journal of pathology 2006;209(1):95-105.
2006: Anja Thielitz; Dirk Reinhold; Robert Vetter; Uwe Lendeckel; Thilo Kähne; Ute Bank; Martin Helmuth; Klaus Neubert; Jürgen Faust; Roland Hartig; Sabine Wrenger; Christos Zouboulis; Siegfried Ansorge; Harald Gollnick
Possible role of DP IV inhibitors in acne therapy.
Advances in experimental medicine and biology 2006;575():163-7.
2005: Stefan Braeuninger; Kathrin Chamaon; Siegfried Kropf; Christian Mawrin; Falk R Wiedemann; Roland Hartig; S Schoeler; Knut Dietzmann; Elmar Kirches
Short incubation with 2-methoxyestradiol kills malignant glioma cells independent of death receptor 5 upregulation.
Clinical neuropathology 2005;24(4):175-83.
2005: Sabine Brandt; Terry Kwok; Roland Hartig; Wolfgang König; Steffen Backert
NF-kappaB activation and potentiation of proinflammatory responses by the Helicobacter pylori CagA protein.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(26):9300-5.
2005: Thomas Kalinski; Sabine Krueger; Antje-Friederike Pelz; Peter Wieacker; Roland Hartig; Martin Röpke; Regine Schneider-Stock; Frank Dombrowski; Albert Roessner
Establishment and characterization of the permanent human cell line C3842 derived from a secondary chondrosarcoma in Ollier's disease.
Virchows Archiv : an international journal of pathology 2005;446(3):287-99.
2005: Regine Schneider-Stock; Mona Diab-Assef; Astrid Rohrbeck; Charlotte Foltzer-Jourdainne; Carsten Boltze; Roland Hartig; Peter Schönfeld; Albert Roessner; Hala Gali-Muhtasib
5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
The Journal of pharmacology and experimental therapeutics 2005;312(2):525-36.
2004: Hala Gali-Muhtasib; Mona Diab-Assaf; Carsten Boltze; Josianne Al-Hmaira; Roland Hartig; Albert Roessner; Regine Schneider-Stock
Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
International journal of oncology 2004;25(4):857-66.
2004: Frank Bühling; Christoph Röcken; Frank Brasch; Roland Hartig; Yoshiyuki Yasuda; Paul Saftig; Dieter Brömme; Tobias Welte
Pivotal role of cathepsin K in lung fibrosis.
The American journal of pathology 2004;164(6):2203-16.
2004: Regine Schneider-Stock; Christian Mawrin; Christiane Motsch; Carsten Boltze; Brigitte Peters; Roland Hartig; Peter Buhtz; Anja Giers; Astrid Rohrbeck; Bernd Freigang; Albert Roessner
Retention of the arginine allele in codon 72 of the p53 gene correlates with poor apoptosis in head and neck cancer.
The American journal of pathology 2004;164(4):1233-41.
2003: Thomas Wex; Heike Wex; Roland Hartig; Skadi Wilhelmsen; Peter Malfertheiner
Functional involvement of cathepsin W in the cytotoxic activity of NK-92 cells.
FEBS letters 2003;552(2-3):115-9.