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Daniel Hartl

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Brown Kyle M; Depristo Mark A; Weinreich Daniel M; Hartl Daniel L
Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways.
Lozovsky Elena R; Chookajorn Thanat; Brown Kyle M; Imwong Mallika; Shaw Philip J; Kamchonwongpaisan Sumalee; Neafsey Daniel E; Weinreich Daniel M; Hartl Daniel L
Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
Bedford Trevor; Hartl Daniel L
Optimization of gene expression by natural selection.

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All Publications

2009: Brown Kyle M; Depristo Mark A; Weinreich Daniel M; Hartl Daniel L
Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways.
Molecular biology and evolution 2009;26(11):2455-62.
2009: Lozovsky Elena R; Chookajorn Thanat; Brown Kyle M; Imwong Mallika; Shaw Philip J; Kamchonwongpaisan Sumalee; Neafsey Daniel E; Weinreich Daniel M; Hartl Daniel L
Stepwise acquisition of pyrimethamine resistance in the malaria parasite.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(29):12025-30.
2009: Bedford Trevor; Hartl Daniel L
Optimization of gene expression by natural selection.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(4):1133-8.
2009: Rogers Rebekah L; Bedford Trevor; Hartl Daniel L
Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster.
Genetics 2009;181(1):313-22.
2008: Lemos Bernardo; Araripe Luciana O; Fontanillas Pierre; Hartl Daniel L
Dominance and the evolutionary accumulation of cis- and trans-effects on gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14471-6.
2008: Bedford Trevor; Hartl Daniel L
Overdispersion of the molecular clock: temporal variation of gene-specific substitution rates in Drosophila.
Molecular biology and evolution 2008;25(8):1631-8.
2008: Baines John F; Sawyer Stanley A; Hartl Daniel L; Parsch John
Effects of X-linkage and sex-biased gene expression on the rate of adaptive protein evolution in Drosophila.
Molecular biology and evolution 2008;25(8):1639-50.
2008: Lynch Michael; Sung Way; Morris Krystalynne; Coffey Nicole; Landry Christian R; Dopman Erik B; Dickinson W Joseph; Okamoto Kazufusa; Kulkarni Shilpa; Hartl Daniel L; Thomas W Kelley
A genome-wide view of the spectrum of spontaneous mutations in yeast.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(27):9272-7.
2008: Brown Kyle M; Landry Christian R; Hartl Daniel L; Cavalieri Duccio
Cascading transcriptional effects of a naturally occurring frameshift mutation in Saccharomyces cerevisiae.
Molecular ecology 2008;17(12):2985-97.
2008: Amodu Olukemi K; Hartl Daniel L; Roy Scott William
Patterns of polymorphism in genomic regions flanking three highly polymorphic surface antigens in Plasmodium falciparum.
Molecular and biochemical parasitology 2008;159(1):1-6.
2008: Karunaweera Nadira D; Ferreira Marcelo U; Munasinghe Anusha; Barnwell John W; Collins William E; King Christopher L; Kawamoto Fumihiko; Hartl Daniel L; Wirth Dyann F
Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax.
Gene 2008;410(1):105-12.
2008: Lemos Bernardo; Araripe Luciana O; Hartl Daniel L
Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences.
Science (New York, N.Y.) 2008;319(5859):91-3.
2008: Neafsey Daniel E; Schaffner Stephen F; Volkman Sarah K; Park Daniel; Montgomery Philip; Milner Danny A; Lukens Amanda; Rosen David; Daniels Rachel; Houde Nathan; Cortese Joseph F; Tyndall Erin; Gates Casey; Stange-Thomann Nicole; Sarr Ousmane; Ndiaye Daouda; Ndir Omar; Mboup Soulyemane; Ferreira Marcelo U; Moraes Sandra do Lago; Dash Aditya P; Chitnis Chetan E; Wiegand Roger C; Hartl Daniel L; Birren Bruce W; Lander Eric S; Sabeti Pardis C; Wirth Dyann F
Genome-wide SNP genotyping highlights the role of natural selection in Plasmodium falciparum population divergence.
Genome biology 2008;9(12):R171.
2007: Dopman Erik B; Hartl Daniel L
A portrait of copy-number polymorphism in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19920-5.
2007: Chookajorn Thanat; Costanzo Marna S; Hartl Daniel L; Deitsch Kirk W
Malaria: a peek at the var variorum.
Trends in parasitology 2007;23(12):563-5.
2007: Fontanillas Pierre; Hartl Daniel L; Reuter Max
Genome organization and gene expression shape the transposable element distribution in the Drosophila melanogaster euchromatin.
PLoS genetics 2007;3(11):e210.
2007: Tao Yun; Araripe Luciana; Kingan Sarah B; Ke Yeyan; Xiao Hailian; Hartl Daniel L
A sex-ratio meiotic drive system in Drosophila simulans. II: an X-linked distorter.
PLoS biology 2007;5(11):e293.
2007: Tao Yun; Masly John P; Araripe Luciana; Ke Yeyan; Hartl Daniel L
A sex-ratio meiotic drive system in Drosophila simulans. I: an autosomal suppressor.
PLoS biology 2007;5(11):e292.
2007: Landry C R; Hartl D L; Ranz J M
Genome clashes in hybrids: insights from gene expression.
Heredity 2007;99(5):483-93.
2007: DePristo Mark A; Hartl Daniel L; Weinreich Daniel M
Mutational reversions during adaptive protein evolution.
Molecular biology and evolution 2007;24(8):1608-10.
2007: Landry Christian R; Lemos Bernardo; Rifkin Scott A; Dickinson W J; Hartl Daniel L
Genetic properties influencing the evolvability of gene expression.
Science (New York, N.Y.) 2007;317(5834):118-21.
2007: Sawyer Stanley A; Parsch John; Zhang Zhi; Hartl Daniel L
Prevalence of positive selection among nearly neutral amino acid replacements in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(16):6504-10.
2007: Ferreira Marcelo U; Karunaweera Nadira D; da Silva-Nunes Monica; da Silva Natal S; Wirth Dyann F; Hartl Daniel L
Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia.
The Journal of infectious diseases 2007;195(8):1218-26.
2007: Hartl Daniel L; Fairbanks Daniel J
Mud sticks: on the alleged falsification of Mendel's data.
Genetics 2007;175(3):975-9.
2007: Landry Christian R; Castillo-Davis Cristian I; Ogura Atsushi; Liu Jun S; Hartl Daniel L
Systems-level analysis and evolution of the phototransduction network in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3283-8.
2007: Chookajorn Thanat; Dzikowski Ron; Frank Matthias; Li Felomena; Jiwani Alisha Z; Hartl Daniel L; Deitsch Kirk W
Epigenetic memory at malaria virulence genes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(3):899-902.
2007: Volkman Sarah K; Sabeti Pardis C; DeCaprio David; Neafsey Daniel E; Schaffner Stephen F; Milner Danny A; Daily Johanna P; Sarr Ousmane; Ndiaye Daouda; Ndir Omar; Mboup Soulyemane; Duraisingh Manoj T; Lukens Amanda; Derr Alan; Stange-Thomann Nicole; Waggoner Skye; Onofrio Robert; Ziaugra Liuda; Mauceli Evan; Gnerre Sante; Jaffe David B; Zainoun Joanne; Wiegand Roger C; Birren Bruce W; Hartl Daniel L; Galagan James E; Lander Eric S; Wirth Dyann F
A genome-wide map of diversity in Plasmodium falciparum.
Nature genetics 2007;39(1):113-9.
2007: Volkman Sarah K; Lozovsky Elena; Barry Alyssa E; Bedford Trevor; Bethke Lara; Myrick Alissa; Day Karen P; Hartl Daniel L; Wirth Dyann F; Sawyer Stanley A
Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum.
Gene 2007;387(1-2):1-6.
2006: Bethke Lara L; Zilversmit Martine; Nielsen Kaare; Daily Johanna; Volkman Sarah K; Ndiaye Daouda; Lozovsky Elena R; Hartl Daniel L; Wirth Dyann F
Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum.
Molecular and biochemical parasitology 2006;150(1):10-24.
2006: Chookajorn Thanat; Hartl Daniel L
Position-specific polymorphism of Plasmodium falciparum Stuttering motif in a PHISTc PFI1780w.
Experimental parasitology 2006;114(2):126-8.
2006: DePristo Mark A; Zilversmit Martine M; Hartl Daniel L
On the abundance, amino acid composition, and evolutionary dynamics of low-complexity regions in proteins.
Gene 2006;378():19-30.
2006: Barry Alyssa E; Leliwa-Sytek Aleksandra; Man Kitty; Kasper Jacob M; Hartl Daniel L; Day Karen P
Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum.
Gene 2006;376(2):163-73.
2006: Ponce Rita; Hartl Daniel L
The evolution of the novel Sdic gene cluster in Drosophila melanogaster.
Gene 2006;376(2):174-83.
2006: Roy Scott William; Hartl Daniel L
Very little intron loss/gain in Plasmodium: intron loss/gain mutation rates and intron number.
Genome research 2006;16(6):750-6.
2006: Weinreich Daniel M; Delaney Nigel F; Depristo Mark A; Hartl Daniel L
Darwinian evolution can follow only very few mutational paths to fitter proteins.
Science (New York, N.Y.) 2006;312(5770):111-4.
2006: Landry Christian R; Townsend Jeffrey P; Hartl Daniel L; Cavalieri Duccio
Ecological and evolutionary genomics of Saccharomyces cerevisiae.
Molecular ecology 2006;15(3):575-91.
2006: Landry Christian R; Oh Julia; Hartl Daniel L; Cavalieri Duccio
Genome-wide scan reveals that genetic variation for transcriptional plasticity in yeast is biased towards multi-copy and dispensable genes.
Gene 2006;366(2):343-51.
2005: Landry Christian R; Wittkopp Patricia J; Taubes Clifford H; Ranz Jose M; Clark Andrew G; Hartl Daniel L
Compensatory cis-trans evolution and the dysregulation of gene expression in interspecific hybrids of Drosophila.
Genetics 2005;171(4):1813-22.
2005: Blumenstiel Justin P; Hartl Daniel L
Evidence for maternally transmitted small interfering RNA in the repression of transposition in Drosophila virilis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(44):15965-70.
2005: DePristo Mark A; Weinreich Daniel M; Hartl Daniel L
Missense meanderings in sequence space: a biophysical view of protein evolution.
Nature reviews. Genetics 2005;6(9):678-87.
2005: Neafsey Daniel E; Hartl Daniel L; Berriman Matt
Evolution of noncoding and silent coding sites in the Plasmodium falciparum and Plasmodium reichenowi genomes.
Molecular biology and evolution 2005;22(7):1621-6.
2005: Neafsey Daniel E; Hartl Daniel L
Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages.
Gene 2005;350(2):161-71.
2005: Lemos Bernardo; Bettencourt Brian R; Meiklejohn Colin D; Hartl Daniel L
Evolution of proteins and gene expression levels are coupled in Drosophila and are independently associated with mRNA abundance, protein length, and number of protein-protein interactions.
Molecular biology and evolution 2005;22(5):1345-54.
2005: Lemos Bernardo; Meiklejohn Colin D; Cáceres Mario; Hartl Daniel L
Rates of divergence in gene expression profiles of primates, mice, and flies: stabilizing selection and variability among functional categories.
Evolution; international journal of organic evolution 2005;59(1):126-37.
2005: Kulathinal Rob J; Hartl Daniel L
The latest buzz in comparative genomics.
Genome biology 2005;6(1):201.
2004: Neafsey Daniel E; Blumenstiel Justin P; Hartl Daniel L
Different regulatory mechanisms underlie similar transposable element profiles in pufferfish and fruitflies.
Molecular biology and evolution 2004;21(12):2310-8.
2004: Kulathinal Rob J; Bettencourt Brian R; Hartl Daniel L
Compensated deleterious mutations in insect genomes.
Science (New York, N.Y.) 2004;306(5701):1553-4.
2004: Lemos Bernardo; Meiklejohn Colin D; Hartl Daniel L
Regulatory evolution across the protein interaction network.
Nature genetics 2004;36(10):1059-60.
2004: Meiklejohn Colin D; Kim Yuseob; Hartl Daniel L; Parsch John
Identification of a locus under complex positive selection in Drosophila simulans by haplotype mapping and composite-likelihood estimation.
Genetics 2004;168(1):265-79.
2004: Castillo-Davis Cristian I; Hartl Daniel L; Achaz Guillaume
cis-Regulatory and protein evolution in orthologous and duplicate genes.
Genome research 2004;14(8):1530-6.
2004: Castillo-Davis Cristian I; Bedford Trevor B C; Hartl Daniel L
Accelerated rates of intron gain/loss and protein evolution in duplicate genes in human and mouse malaria parasites.
Molecular biology and evolution 2004;21(7):1422-7.
2004: Castillo-Davis Cristian I; Kondrashov Fyodor A; Hartl Daniel L; Kulathinal Rob J
The functional genomic distribution of protein divergence in two animal phyla: coevolution, genomic conflict, and constraint.
Genome research 2004;14(5):802-11.
2004: Ranz José M; Namgyal Kalsang; Gibson Greg; Hartl Daniel L
Anomalies in the expression profile of interspecific hybrids of Drosophila melanogaster and Drosophila simulans.
Genome research 2004;14(3):373-9.
2004: Hartl Daniel L
The origin of malaria: mixed messages from genetic diversity.
Nature reviews. Microbiology 2004;2(1):15-22.
2003: Castillo-Davis Cristian I; Hartl Daniel L
Conservation, relocation and duplication in genome evolution.
Trends in genetics : TIG 2003;19(11):593-7.
2003: Barry Alyssa E; Leliwa Aleksandra; Choi Mehee; Nielsen Kaare M; Hartl Daniel L; Day Karen P
DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum.
Molecular and biochemical parasitology 2003;130(2):143-7.
2003: Meiklejohn Colin D; Parsch John; Ranz José M; Hartl Daniel L
Rapid evolution of male-biased gene expression in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9894-9.
2003: Ranz José María; Ponce Ana Rita; Hartl Daniel L; Nurminsky Dmitry
Origin and evolution of a new gene expressed in the Drosophila sperm axoneme.
Genetica 2003;118(2-3):233-44.
2003: Ranz José M; Castillo-Davis Cristian I; Meiklejohn Colin D; Hartl Daniel L
Sex-dependent gene expression and evolution of the Drosophila transcriptome.
Science (New York, N.Y.) 2003;300(5626):1742-5.
2003: Townsend Jeffrey P; Cavalieri Duccio; Hartl Daniel L
Population genetic variation in genome-wide gene expression.
Molecular biology and evolution 2003;20(6):955-63.
2003: Townsend Jeffrey P; Nielsen Kaare M; Fisher Daniel S; Hartl Daniel L
Horizontal acquisition of divergent chromosomal DNA in bacteria: effects of mutator phenotypes.
Genetics 2003;164(1):13-21.
2003: Castillo-Davis Cristian I; Hartl Daniel L
GeneMerge--post-genomic analysis, data mining, and hypothesis testing.
Bioinformatics (Oxford, England) 2003;19(7):891-2.
2003: Nielsen Kaare M; Kasper Jacob; Choi Mehee; Bedford Trevor; Kristiansen Kurt; Wirth Dyann F; Volkman Sarah K; Lozovsky Elena R; Hartl Daniel L
Gene conversion as a source of nucleotide diversity in Plasmodium falciparum.
Molecular biology and evolution 2003;20(5):726-34.
2003: Bustamante Carlos D; Nielsen Rasmus; Hartl Daniel L
Maximum likelihood and Bayesian methods for estimating the distribution of selective effects among classes of mutations using DNA polymorphism data.
Theoretical population biology 2003;63(2):91-103.
2003: Winzeler Elizabeth A; Castillo-Davis Cristian I; Oshiro Guy; Liang David; Richards Daniel R; Zhou Yingyao; Hartl Daniel L
Genetic diversity in yeast assessed with whole-genome oligonucleotide arrays.
Genetics 2003;163(1):79-89.
2003: Volkman Sarah K; Hartl Daniel L
Parasitology. A game of cat and mouth.
Science (New York, N.Y.) 2003;299(5605):353-4.
2003: Cavalieri Duccio; McGovern Patrick E; Hartl Daniel L; Mortimer Robert; Polsinelli Mario
Evidence for S. cerevisiae fermentation in ancient wine.
Journal of molecular evolution 2003;57 Suppl 1():S226-32.
2003: Sawyer Stanley A; Kulathinal Rob J; Bustamante Carlos D; Hartl Daniel L
Bayesian analysis suggests that most amino acid replacements in Drosophila are driven by positive selection.
Journal of molecular evolution 2003;57 Suppl 1():S154-64.
2002: Blumenstiel Justin P; Hartl Daniel L; Lozovsky Elena R
Patterns of insertion and deletion in contrasting chromatin domains.
Molecular biology and evolution 2002;19(12):2211-25.
2002: Volkman Sarah K; Hartl Daniel L; Wirth Dyann F; Nielsen Kaare M; Choi Mehee; Batalov Serge; Zhou Yingyao; Plouffe David; Le Roch Karine G; Abagyan Ruben; Winzeler Elizabeth A
Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum.
Science (New York, N.Y.) 2002;298(5591):216-8.
2002: Castillo-Davis Cristian I; Mekhedov Sergei L; Hartl Daniel L; Koonin Eugene V; Kondrashov Fyodor A
Selection for short introns in highly expressed genes.
Nature genetics 2002;31(4):415-8.
2002: Grosu Paul; Townsend Jeffrey P; Hartl Daniel L; Cavalieri Duccio
Pathway Processor: a tool for integrating whole-genome expression results into metabolic networks.
Genome research 2002;12(7):1121-6.
2002: Hartl Daniel L; Volkman Sarah K; Nielsen Kaare M; Barry Alyssa E; Day Karen P; Wirth Dyann F; Winzeler Elizabeth A
The paradoxical population genetics of Plasmodium falciparum.
Trends in parasitology 2002;18(6):266-72.
2002: Castillo-Davis Cristian I; Hartl Daniel L
Genome evolution and developmental constraint in Caenorhabditis elegans.
Molecular biology and evolution 2002;19(5):728-35.
2002: Bustamante Carlos D; Nielsen Rasmus; Sawyer Stanley A; Olsen Kenneth M; Purugganan Michael D; Hartl Daniel L
The cost of inbreeding in Arabidopsis.
Nature 2002;416(6880):531-4.
2002: Lozovsky Elena R; Nurminsky Dmitry; Wimmer Ernst A; Hartl Daniel L
Unexpected stability of mariner transgenes in Drosophila.
Genetics 2002;160(2):527-35.
2002: Lohe Allan R; Hartl Daniel L
Efficient mobilization of mariner in vivo requires multiple internal sequences.
Genetics 2002;160(2):519-26.
2002: Bustamante Carlos D; Nielsen Rasmus; Hartl Daniel L
A maximum likelihood method for analyzing pseudogene evolution: implications for silent site evolution in humans and rodents.
Molecular biology and evolution 2002;19(1):110-7.
2002: Townsend Jeffrey P; Hartl Daniel L
Bayesian analysis of gene expression levels: statistical quantification of relative mRNA level across multiple strains or treatments.
Genome biology 2002;3(12):RESEARCH0071.
2001: Bustamante C D; Wakeley J; Sawyer S; Hartl D L
Directional selection and the site-frequency spectrum.
Genetics 2001;159(4):1779-88.
2001: Parsch J; Meiklejohn C D; Hartl D L
Patterns of DNA sequence variation suggest the recent action of positive selection in the janus-ocnus region of Drosophila simulans.
Genetics 2001;159(2):647-57.
2001: Volkman S K; Barry A E; Lyons E J; Nielsen K M; Thomas S M; Choi M; Thakore S S; Day K P; Wirth D F; Hartl D L
Recent origin of Plasmodium falciparum from a single progenitor.
Science (New York, N.Y.) 2001;293(5529):482-4.
2001: Parsch J; Meiklejohn C D; Hauschteck-Jungen E; Hunziker P; Hartl D L
Molecular evolution of the ocnus and janus genes in the Drosophila melanogaster species subgroup.
Molecular biology and evolution 2001;18(5):801-11.
2000: Hartl D L
Molecular melodies in high and low C.
Nature reviews. Genetics 2000;1(2):145-9.
2000: Cavalieri D; Townsend J P; Hartl D L
Manifold anomalies in gene expression in a vineyard isolate of Saccharomyces cerevisiae revealed by DNA microarray analysis.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12369-74.
2000: Parsch J; Russell J A; Beerman I; Hartl D L; Stephan W
Deletion of a conserved regulatory element in the Drosophila Adh gene leads to increased alcohol dehydrogenase activity but also delays development.
Genetics 2000;156(1):219-27.
2000: Petrov D A; Hartl D L
Pseudogene evolution and natural selection for a compact genome.
The Journal of heredity 2000;91(3):221-7.
2000: Bustamante C D; Townsend J P; Hartl D L
Solvent accessibility and purifying selection within proteins of Escherichia coli and Salmonella enterica.
Molecular biology and evolution 2000;17(2):301-8.
2000: Lohe A R; Timmons C; Beerman I; Lozovskaya E R; Hartl D L
Self-inflicted wounds, template-directed gap repair and a recombination hotspot. Effects of the mariner transposase.
Genetics 2000;154(2):647-56.
2000: Townsend J P; Hartl D L
The kinetics of transposable element autoregulation.
Genetica 2000;108(3):229-37.
1999: Lozovskaya E R; Nurminsky D I; Petrov D A; Hartl D L
Genome size as a mutation-selection-drift process.
Genes & genetic systems 1999;74(5):201-7.
1999: Siegal M L; Hartl D L
Oviposition-site preference in Drosophila following interspecific gene transfer of the Alcohol dehydrogenase locus.
Behavior genetics 1999;29(3):199-204.
1999: Boyd E F; Hartl D L
Analysis of the type 1 pilin gene cluster fim in Salmonella: its distinct evolutionary histories in the 5' and 3' regions.
Journal of bacteriology 1999;181(4):1301-8.
1998: Siegal M L; Hartl D L
An experimental test for lineage-specific position effects on alcohol dehydrogenase (Adh) genes in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15513-8.
1998: Nurminsky D I; Nurminskaya M V; De Aguiar D; Hartl D L
Selective sweep of a newly evolved sperm-specific gene in Drosophila.
Nature 1998;396(6711):572-5.
1998: Nurminsky D I; Nurminskaya M V; Benevolenskaya E V; Shevelyov Y Y; Hartl D L; Gvozdev V A
Cytoplasmic dynein intermediate-chain isoforms with different targeting properties created by tissue-specific alternative splicing.
Molecular and cellular biology 1998;18(11):6816-25.
1998: Boyd E F; Hartl D L
Diversifying selection governs sequence polymorphism in the major adhesin proteins fimA, papA, and sfaA of Escherichia coli.
Journal of molecular evolution 1998;47(3):258-67.
1998: Boyd E F; Hartl D L
Salmonella virulence plasmid. Modular acquisition of the spv virulence region by an F-plasmid in Salmonella enterica subspecies I and insertion into the chromosome of subspecies II, IIIa, IV and VII isolates.
Genetics 1998;149(3):1183-90.
1998: Vieira J; Vieira C P; Hartl D L; Lozovskaya E R
Factors contributing to the hybrid dysgenesis syndrome in Drosophila virilis.
Genetical research 1998;71(2):109-17.
1998: Petrov D A; Hartl D L
High rate of DNA loss in the Drosophila melanogaster and Drosophila virilis species groups.
Molecular biology and evolution 1998;15(3):293-302.
1998: Boyd E F; Hartl D L
Chromosomal regions specific to pathogenic isolates of Escherichia coli have a phylogenetically clustered distribution.
Journal of bacteriology 1998;180(5):1159-65.
1998: Hartl D L; Taubes C H
Towards a theory of evolutionary adaptation.
Genetica 1998;102-103(1-6):525-33.
1997: Petrov D A; Hartl D L
Trash DNA is what gets thrown away: high rate of DNA loss in Drosophila.
Gene 1997;205(1-2):279-89.
1997: Vieira C P; Vieira J; Hartl D L
The evolution of small gene clusters: evidence for an independent origin of the maltase gene cluster in Drosophila virilis and Drosophila melanogaster.
Molecular biology and evolution 1997;14(10):985-93.
1997: Vieira J; Vieira C P; Hartl D L; Lozovskaya E R
Discordant rates of chromosome evolution in the Drosophila virilis species group.
Genetics 1997;147(1):223-30.
1997: Vieira J; Vieira C P; Hartl D L; Lozovskaya E R
A framework physical map of Drosophila virilis based on P1 clones: applications in genome evolution.
Chromosoma 1997;106(2):99-107.
1997: Boyd E F; Hartl D L
Nonrandom location of IS1 elements in the genomes of natural isolates of Escherichia coli.
Molecular biology and evolution 1997;14(7):725-32.
1997: Hartl D L
Mariner sails into Leishmania.
Science (New York, N.Y.) 1997;276(5319):1659-60.
1997: Hartl D L; Lozovskaya E R; Nurminsky D I; Lohe A R
What restricts the activity of mariner-like transposable elements.
Trends in genetics : TIG 1997;13(5):197-201.
1997: Boyd E F; Hartl D L
Recent horizontal transmission of plasmids between natural populations of Escherichia coli and Salmonella enterica.
Journal of bacteriology 1997;179(5):1622-7.
1997: Lohe A R; De Aguiar D; Hartl D L
Mutations in the mariner transposase: the D,D(35)E consensus sequence is nonfunctional.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1293-7.
1997: Hartl D L; Lohe A R; Lozovskaya E R
Modern thoughts on an ancyent marinere: function, evolution, regulation.
Annual review of genetics 1997;31():337-58.
1997: Hartl D L; Lohe A R; Lozovskaya E R
Regulation of the transposable element mariner.
Genetica 1997;100(1-3):177-84.
1996: Petrov D A; Lozovskaya E R; Hartl D L
High intrinsic rate of DNA loss in Drosophila.
Nature 1996;384(6607):346-9.
1996: Lohe A R; Sullivan D T; Hartl D L
Subunit interactions in the mariner transposase.
Genetics 1996;144(3):1087-95.
1996: Siegal M L; Hartl D L
Transgene Coplacement and high efficiency site-specific recombination with the Cre/loxP system in Drosophila.
Genetics 1996;144(2):715-26.
1996: Lohe A R; Hartl D L
Reduced germline mobility of a mariner vector containing exogenous DNA: effect of size or site?
Genetics 1996;143(3):1299-306.
1996: Boyd E F; Hill C W; Rich S M; Hartl D L
Mosaic structure of plasmids from natural populations of Escherichia coli.
Genetics 1996;143(3):1091-100.
1996: Lohe A R; Hartl D L
Germline transformation of Drosophila virilis with the transposable element mariner.
Genetics 1996;143(1):365-74.
1996: Lohe A R; Hartl D L
Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation.
Molecular biology and evolution 1996;13(4):549-55.
1996: Ayala F J; Wetterer J K; Longino J T; Hartl D L
Molecular phylogeny of Azteca ants (Hymenoptera:Formicidae) and the colonization of Cecropia trees.
Molecular phylogenetics and evolution 1996;5(2):423-8.
1996: Nurminsky D I; Hartl D L
Sequence scanning: A method for rapid sequence acquisition from large-fragment DNA clones.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(4):1694-8.
1996: Lozovskaya E R; Nurminsky D I; Hartl D L; Sullivan D T
Germline transformation of Drosophila virilis mediated by the transposable element hobo.
Genetics 1996;142(1):173-7.
1996: Nurminsky D I; Moriyama E N; Lozovskaya E R; Hartl D L
Molecular phylogeny and genome evolution in the Drosophila virilis species group: duplications of the alcohol dehydrogenase gene.
Molecular biology and evolution 1996;13(1):132-49.
1996: Hartl D L; Ochman H
Inverse polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 1996;58():293-301.
1995: Lozovskaya E R; Hartl D L; Petrov D A
Genomic regulation of transposable elements in Drosophila.
Current opinion in genetics & development 1995;5(6):768-73.
1995: Petrov D A; Schutzman J L; Hartl D L; Lozovskaya E R
Diverse transposable elements are mobilized in hybrid dysgenesis in Drosophila virilis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):8050-4.
1995: Lohe A R; Lidholm D A; Hartl D L
Genotypic effects, maternal effects and grand-maternal effects of immobilized derivatives of the transposable element mariner.
Genetics 1995;140(1):183-92.
1995: Lohe A R; Moriyama E N; Lidholm D A; Hartl D L
Horizontal transmission, vertical inactivation, and stochastic loss of mariner-like transposable elements.
Molecular biology and evolution 1995;12(1):62-72.
1994: Hartl D L; Moriyama E N; Sawyer S A
Selection intensity for codon bias.
Genetics 1994;138(1):227-34.
1994: Ayala F J; Krane D E; Hartl D L
Genetic variation in IncI1-ColIb plasmids.
Journal of molecular evolution 1994;39(2):129-33.
1994: Hartl D L; Nurminsky D I; Jones R W; Lozovskaya E R
Genome structure and evolution in Drosophila: applications of the framework P1 map.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):6824-9.
1994: Carulli J P; Chen D M; Stark W S; Hartl D L
Phylogeny and physiology of Drosophila opsins.
Journal of molecular evolution 1994;38(3):250-62.
1994: Hartl D L; Lozovskaya E R
Genome evolution: between the nucleosome and the chromosome.
EXS 1994;69():579-92.
1994: Hartl D L; Ochman H
Inverse polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 1994;31():187-96.
1993: Ayala F J; Hartl D L
Molecular drift of the bride of sevenless (boss) gene in Drosophila.
Molecular biology and evolution 1993;10(5):1030-40.
1993: Nurminsky D I; Hartl D L
Amplification of the ends of DNA fragments cloned in bacteriophage P1.
BioTechniques 1993;15(2):201-2, 206-8.
1993: Lidholm D A; Lohe A R; Hartl D L
The transposable element mariner mediates germline transformation in Drosophila melanogaster.
Genetics 1993;134(3):859-68.
1993: Moriyama E N; Hartl D L
Codon usage bias and base composition of nuclear genes in Drosophila.
Genetics 1993;134(3):847-58.
1993: Carulli J P; Krane D E; Hartl D L; Ochman H
Compositional heterogeneity and patterns of molecular evolution in the Drosophila genome.
Genetics 1993;134(3):837-45.
1993: Lozovskaya E R; Petrov D A; Hartl D L
A combined molecular and cytogenetic approach to genome evolution in Drosophila using large-fragment DNA cloning.
Chromosoma 1993;102(4):253-66.
1993: Lawrence J G; Hartl D L; Ochman H
Sequencing products of polymerase chain reaction.
Methods in enzymology 1993;218():26-35.
1993: Ayala F J; Chang B S; Hartl D L
Molecular evolution of the Rh3 gene in Drosophila.
Genetica 1993;92(1):23-32.
1992: Danilevskaya O N; Petrov D A; Pavlova M N; Koga A; Kurenova E V; Hartl D L
A repetitive DNA element, associated with telomeric sequences in Drosophila melanogaster, contains open reading frames.
Chromosoma 1992;102(1):32-40.
1992: Krane D E; Allen R W; Sawyer S A; Petrov D A; Hartl D L
Genetic differences at four DNA typing loci in Finnish, Italian, and mixed Caucasian populations.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(22):10583-7.
1992: Hartl D L; Lozovskaya E R
The Drosophila genome project: current status of the physical map.
Comparative biochemistry and physiology. B, Comparative biochemistry 1992;103(1):1-8.
1992: Carulli J P; Hartl D L
Variable rates of evolution among Drosophila opsin genes.
Genetics 1992;132(1):193-204.
1992: Lawrence J G; Hartl D L
Inference of horizontal genetic transfer from molecular data: an approach using the bootstrap.
Genetics 1992;131(3):753-60.
1992: Hartl D L; Orel V
What did Gregor Mendel think he discovered?
Genetics 1992;131(2):245-53.
1992: Lawrence J G; Ochman H; Hartl D L
The evolution of insertion sequences within enteric bacteria.
Genetics 1992;131(1):9-20.
1992: Capy P; Koga A; David J R; Hartl D L
Sequence analysis of active mariner elements in natural populations of Drosophila simulans.
Genetics 1992;130(3):499-506.
1992: Hartl D L; Ajioka J W; Cai H; Lohe A R; Lozovskaya E R; Smoller D A; Duncan I W
Towards a Drosophila genome map.
Trends in genetics : TIG 1992;8(2):70-5.
1992: Hartl D L; Lozovskaya E R; Lawrence J G
Nonautonomous transposable elements in prokaryotes and eukaryotes.
Genetica 1992;86(1-3):47-53.
1991: Maruyama K; Hartl D L
Evidence for interspecific transfer of the transposable element mariner between Drosophila and Zaprionus.
Journal of molecular evolution 1991;33(6):514-24.
1991: Capy P; Maruyama K; David J R; Hartl D L
Insertion sites of the transposable element mariner are fixed in the genome of Drosophila sechellia.
Journal of molecular evolution 1991;33(5):450-6.
1991: Krane D E; Hartl D L; Ochman H
Rapid determination of nucleotide content and its application to the study of genome structure.
Nucleic acids research 1991;19(19):5181-5.
1991: Palazzolo M J; Sawyer S A; Martin C H; Smoller D A; Hartl D L
Optimized strategies for sequence-tagged-site selection in genome mapping.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(18):8034-8.
1991: Ajioka J W; Smoller D A; Jones R W; Carulli J P; Vellek A E; Garza D; Link A J; Duncan I W; Hartl D L
Drosophila genome project: one-hit coverage in yeast artificial chromosomes.
Chromosoma 1991;100(8):495-509.
1991: Smoller D A; Petrov D; Hartl D L
Characterization of bacteriophage P1 library containing inserts of Drosophila DNA of 75-100 kilobase pairs.
Chromosoma 1991;100(8):487-94.
1991: Lawrence J G; Hartl D L; Ochman H
Molecular considerations in the evolution of bacterial genes.
Journal of molecular evolution 1991;33(3):241-50.
1991: Lawrence J G; Ochman H; Hartl D L
Molecular and evolutionary relationships among enteric bacteria.
Journal of general microbiology 1991;137(8):1911-21.
1991: Maruyama K; Schoor K D; Hartl D L
Identification of nucleotide substitutions necessary for trans-activation of mariner transposable elements in Drosophila: analysis of naturally occurring elements.
Genetics 1991;128(4):777-84.
1991: Maruyama K; Hartl D L
Evolution of the transposable element mariner in Drosophila species.
Genetics 1991;128(2):319-29.
1991: Medhora M; Maruyama K; Hartl D L
Molecular and functional analysis of the mariner mutator element Mos1 in Drosophila.
Genetics 1991;128(2):311-8.
1991: Garza D; Medhora M; Koga A; Hartl D L
Introduction of the transposable element mariner into the germline of Drosophila melanogaster.
Genetics 1991;128(2):303-10.
1991: Danilevskaya O N; Kurenova E V; Pavlova M N; Bebehov D V; Link A J; Koga A; Vellek A; Hartl D L
He-T family DNA sequences in the Y chromosome of Drosophila melanogaster share homology with the X-linked stellate genes.
Chromosoma 1991;100(2):118-24.
1991: Lawrence J G; Hartl D L
Unusual codon bias occurring within insertion sequences in Escherichia coli.
Genetica 1991;84(1):23-9.
1990: Garza D; Medhora M M; Hartl D L
Drosophila nonsense suppressors: functional analysis in Saccharomyces cerevisiae, Drosophila tissue culture cells and Drosophila melanogaster.
Genetics 1990;126(3):625-37.
1990: DuBose R F; Hartl D L
The molecular evolution of bacterial alkaline phosphatase: correlating variation among enteric bacteria to experimental manipulations of the protein.
Molecular biology and evolution 1990;7(6):547-77.
1990: Ochman H; Ajioka J W; Garza D; Hartl D L
Inverse polymerase chain reaction.
Bio/technology (Nature Publishing Company) 1990;8(8):759-60.
1990: Bryan G; Garza D; Hartl D
Insertion and excision of the transposable element mariner in Drosophila.
Genetics 1990;125(1):103-14.
1989: DuBose R F; Hartl D L
An experimental approach to testing modular evolution: directed replacement of alpha-helices in a bacterial protein.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9966-70.
1989: Garza D; Ajioka J W; Burke D T; Hartl D L
Mapping the Drosophila genome with yeast artificial chromosomes.
Science (New York, N.Y.) 1989;246(4930):641-6.
1989: Hartl D L
Evolving theories of enzyme evolution.
Genetics 1989;122(1):1-6.
1989: Hall B G; Parker L L; Betts P W; DuBose R F; Sawyer S A; Hartl D L
IS103, a new insertion element in Escherichia coli: characterization and distribution in natural populations.
Genetics 1989;121(3):423-31.
1989: Lawrence J G; Dykhuizen D E; DuBose R F; Hartl D L
Phylogenetic analysis using insertion sequence fingerprinting in Escherichia coli.
Molecular biology and evolution 1989;6(1):1-14.
1989: Hartl D L
The physiology of weak selection.
Genome / National Research Council Canada = Génome / Conseil national de recherches Canada 1989;31(1):183-9.
1988: Ochman H; Gerber A S; Hartl D L
Genetic applications of an inverse polymerase chain reaction.
Genetics 1988;120(3):621-3.
1988: Miller R D; Dykhuizen D E; Hartl D L
Fitness effects of a deletion mutation increasing transcription of the 6-phosphogluconate dehydrogenase gene in Escherichia coli.
Molecular biology and evolution 1988;5(6):691-703.
1988: Dean A M; Dykhuizen D E; Hartl D L
Fitness effects of amino acid replacements in the beta-galactosidase of Escherichia coli.
Molecular biology and evolution 1988;5(5):469-85.
1988: DuBose R F; Dykhuizen D E; Hartl D L
Genetic exchange among natural isolates of bacteria: recombination within the phoA gene of Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):7036-40.
1988: Medhora M M; MacPeek A H; Hartl D L
Excision of the Drosophila transposable element mariner: identification and characterization of the Mos factor.
The EMBO journal 1988;7(7):2185-9.
1988: Bryan G J; Hartl D L
Maternally inherited transposon excision in Drosophila simulans.
Science (New York, N.Y.) 1988;240(4849):215-7.
1988: Hartl D L; Sawyer S A
Why do unrelated insertion sequences occur together in the genome of Escherichia coli?
Genetics 1988;118(3):537-41.
1987: Sawyer S A; Dykhuizen D E; Hartl D L
Confidence interval for the number of selectively neutral amino acid polymorphisms.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(17):6225-8.
1987: Dykhuizen D E; Dean A M; Hartl D L
Metabolic flux and fitness.
Genetics 1987;115(1):25-31.
1987: Sawyer S A; Dykhuizen D E; DuBose R F; Green L; Mutangadura-Mhlanga T; Wolczyk D F; Hartl D L
Distribution and abundance of insertion sequences among natural isolates of Escherichia coli.
Genetics 1987;115(1):51-63.
1986: Dean A M; Dykhuizen D E; Hartl D L
Fitness as a function of beta-galactosidase activity in Escherichia coli.
Genetical research 1986;48(1):1-8.
1985: Hartl D L; Dykhuizen D E; Dean A M
Limits of adaptation: the evolution of selective neutrality.
Genetics 1985;111(3):655-74.
1985: Dykhuizen D E; Sawyer S A; Green L; Miller R D; Hartl D L
Joint distribution of insertion elements IS4 and IS5 in natural isolates of Escherichia coli.
Genetics 1985;111(2):219-31.
1984: Dykhuizen D E; de Framond J; Hartl D L
Potential for hitchhiking in the eda-edd-zwf gene cluster of Escherichia coli.
Genetical research 1984;43(3):229-39.
1984: Dykhuizen D E; de Framond J; Hartl D L
Selective neutrality of glucose-6-phosphate dehydrogenase allozymes in Escherichia coli.
Molecular biology and evolution 1984;1(2):162-70.
1983: Hartl D L; Dykhuizen D E; Miller R D; Green L; de Framond J
Transposable element IS50 improves growth rate of E. coli cells without transposition.
Cell 1983;35(2 Pt 1):503-10.

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