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John Harty

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Anatomy

Living Beings

Disorders

Listeria Infections

Physiology

Chemicals & Drugs

Procedures

Adoptive Transfer

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Co-Publications
Name
34
Badovinac, Vladimir
10
Haring, Jodie
8
Hamilton, Sara
8
White, DW
7
Tvinnereim, Amy
7
Jabbari, Ali
6
Messingham, Kelly
5
Khanolkar, Aaruni
4
Corbin, Gail
4
Porter, Brandon
3
Varga, Steven
3
Butler, Noah
2
Vukmanovic, Stanislav
2
Santori, Fabio
2
Wilson, Rebecca

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Publications

TOP 3
Wirth Thomas C; Pham Nhat-Long L; Harty John T; Badovinac Vladimir P
High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell function.
Schmidt Nathan W; Butler Noah S; Harty John T
CD8 T cell immunity to Plasmodium permits generation of protective antibodies after repeated sporozoite challenge.
Khanolkar Aaruni; Hartwig Stacey M; Haag Brayton A; Meyerholz David K; Epping Lecia L; Haring Jodie S; Varga Steven M; Harty John T
Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome.

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All Publications

2009: Wirth Thomas C; Pham Nhat-Long L; Harty John T; Badovinac Vladimir P
High initial frequency of TCR-transgenic CD8 T cells alters inflammation and pathogen clearance without affecting memory T cell function.
Molecular immunology 2009;47(1):71-8.
2009: Schmidt Nathan W; Butler Noah S; Harty John T
CD8 T cell immunity to Plasmodium permits generation of protective antibodies after repeated sporozoite challenge.
Vaccine 2009;27(44):6103-6.
2009: Khanolkar Aaruni; Hartwig Stacey M; Haag Brayton A; Meyerholz David K; Epping Lecia L; Haring Jodie S; Varga Steven M; Harty John T
Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome.
Journal of virology 2009;83(18):9258-72.
2009: Khanolkar Aaruni; Hartwig Stacey M; Haag Brayton A; Meyerholz David K; Harty John T; Varga Steven M
Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice.
Journal of virology 2009;83(17):8946-56.
2009: Pham Nhat-Long L; Badovinac Vladimir P; Harty John T
A default pathway of memory CD8 T cell differentiation after dendritic cell immunization is deflected by encounter with inflammatory cytokines during antigen-driven proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2337-48.
2009: Wirth Thomas C; Badovinac Vladimir P; Zhao Lichao; Dailey Morris O; Harty John T
Differentiation of central memory CD8 T cells is independent of CD62L-mediated trafficking to lymph nodes.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(10):6195-206.
2009: Haring Jodie S; Harty John T
Interleukin-18-related genes are induced during the contraction phase but do not play major roles in regulating the dynamics or function of the T-cell response to Listeria monocytogenes infection.
Infection and immunity 2009;77(5):1894-903.
2009: Butler Noah S; Harty John T
A "memorable" NK cell discovery.
Cell research 2009;19(3):277-8.
2009: Wirth Thomas; Harty John T
Initial TCR transgenic precursor frequency alters functional behaviour of CD8 T cells responding to acute infection.
Advances in experimental medicine and biology 2009;633():71-80.
2008: Stojakovic Milica; Salazar-Fontana Laura I; Tatari-Calderone Zohreh; Badovinac Vladimir P; Santori Fabio R; Kovalovsky Damian; Sant'Angelo Derek; Harty John T; Vukmanovic Stanislav
Adaptable TCR avidity thresholds for negative selection.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(10):6770-8.
2008: Schmidt Nathan W; Podyminogin Rebecca L; Butler Noah S; Badovinac Vladimir P; Tucker Brad J; Bahjat Keith S; Lauer Peter; Reyes-Sandoval Arturo; Hutchings Claire L; Moore Anne C; Gilbert Sarah C; Hill Adrian V; Bartholomay Lyric C; Harty John T
Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14017-22.
2008: Xue Hai-Hui; Jing Xuefang; Bollenbacher-Reilley Julie; Zhao Dong-Mei; Haring Jodie S; Yang Baoli; Liu Chengyu; Bishop Gail A; Harty John T; Leonard Warren J
Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function.
Molecular and cellular biology 2008;28(13):4300-9.
2008: Haring Jodie S; Jing Xuefang; Bollenbacher-Reilley Julie; Xue Hai-Hui; Leonard Warren J; Harty John T
Constitutive expression of IL-7 receptor alpha does not support increased expansion or prevent contraction of antigen-specific CD4 or CD8 T cells following Listeria monocytogenes infection.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):2855-62.
2008: Harty John T; Badovinac Vladimir P
Shaping and reshaping CD8+ T-cell memory.
Nature reviews. Immunology 2008;8(2):107-19.
2008: Humphreys Troy D; Khanolkar Aaruni; Badovinac Vladimir P; Harty John T
Generation and maintenance of Listeria-specific CD8+ T cell responses in perforin-deficient mice chronically infected with LCMV.
Virology 2008;370(2):310-22.
2007: Messingham Kelly A N; Badovinac Vladimir P; Jabbari Ali; Harty John T
A role for IFN-gamma from antigen-specific CD8+ T cells in protective immunity to Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2457-66.
2007: Badovinac Vladimir P; Harty John T
Manipulating the rate of memory CD8+ T cell generation after acute infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(1):53-63.
2007: Badovinac Vladimir P; Haring Jodie S; Harty John T
Initial T cell receptor transgenic cell precursor frequency dictates critical aspects of the CD8(+) T cell response to infection.
Immunity 2007;26(6):827-41.
2007: Santori Fabio R; Popmihajlov Zoran; Badovinac Vladimir P; Smith Courtney; Radoja Sasa; Harty John T; Vukmanovic Stanislav
TCR beta chain that forms peptide-independent alloreactive TCR transfers reduced reactivity with irrelevant peptide/MHC complex.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(10):6109-14.
2007: Khanolkar Aaruni; Badovinac Vladimir P; Harty John T
CD8 T cell memory development: CD4 T cell help is appreciated.
Immunologic research 2007;39(1-3):94-104.
2006: Haring Jodie S; Harty John T
Aberrant contraction of antigen-specific CD4 T cells after infection in the absence of gamma interferon or its receptor.
Infection and immunity 2006;74(11):6252-63.
2006: Hamilton Sara E; Badovinac Vladimir P; Khanolkar Aaruni; Harty John T
Listeriolysin O-deficient Listeria monocytogenes as a vaccine delivery vehicle: antigen-specific CD8 T cell priming and protective immunity.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):4012-20.
2006: Jabbari Ali; Legge Kevin L; Harty John T
T cell conditioning explains early disappearance of the memory CD8 T cell response to infection.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):3012-8.
2006: Haring Jodie S; Badovinac Vladimir P; Harty John T
Inflaming the CD8+ T cell response.
Immunity 2006;25(1):19-29.
2006: Badovinac Vladimir P; Messingham Kelly A Nordyke; Griffith Thomas S; Harty John T
TRAIL deficiency delays, but does not prevent, erosion in the quality of "helpless" memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):999-1006.
2006: Jabbari Ali; Harty John T
The generation and modulation of antigen-specific memory CD8 T cell responses.
Journal of leukocyte biology 2006;80(1):16-23.
2006: Badovinac Vladimir P; Harty John T
Programming, demarcating, and manipulating CD8+ T-cell memory.
Immunological reviews 2006;211():67-80.
2006: Jabbari Ali; Harty John T
Simultaneous assessment of antigen-stimulated cytokine production and memory subset composition of memory CD8 T cells.
Journal of immunological methods 2006;313(1-2):161-8.
2006: Jabbari Ali; Harty John T
Secondary memory CD8+ T cells are more protective but slower to acquire a central-memory phenotype.
The Journal of experimental medicine 2006;203(4):919-32.
2006: Porter Brandon B; Harty John T
The onset of CD8+-T-cell contraction is influenced by the peak of Listeria monocytogenes infection and antigen display.
Infection and immunity 2006;74(3):1528-36.
2005: Jabbari Ali; Harty John T
Cutting edge: differential self-peptide/MHC requirement for maintaining CD8 T cell function versus homeostatic proliferation.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(8):4829-33.
2005: Haring Jodie S; Badovinac Vladimir P; Olson Matthew R; Varga Steven M; Harty John T
In vivo generation of pathogen-specific Th1 cells in the absence of the IFN-gamma receptor.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(5):3117-22.
2005: Badovinac Vladimir P; Messingham Kelly A N; Jabbari Ali; Haring Jodie S; Harty John T
Accelerated CD8+ T-cell memory and prime-boost response after dendritic-cell vaccination.
Nature medicine 2005;11(7):748-56.
2005: Haring Jodie S; Corbin Gail A; Harty John T
Dynamic regulation of IFN-gamma signaling in antigen-specific CD8+ T cells responding to infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(11):6791-802.
2005: Corbin Gail A; Harty John T
T cells undergo rapid ON/OFF but not ON/OFF/ON cycling of cytokine production in response to antigen.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(2):718-26.
2004: Corbin Gail A; Harty John T
Duration of infection and antigen display have minimal influence on the kinetics of the CD4+ T cell response to Listeria monocytogenes infection.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5679-87.
2004: Tvinnereim Amy R; Hamilton Sara E; Harty John T
Neutrophil involvement in cross-priming CD8+ T cell responses to bacterial antigens.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):1994-2002.
2004: Badovinac Vladimir P; Porter Brandon B; Harty John T
CD8+ T cell contraction is controlled by early inflammation.
Nature immunology 2004;5(8):809-17.
2004: Hamilton Sara E; Porter Brandon B; Messingham Kelly A Nordyke; Badovinac Vladimir P; Harty John T
MHC class Ia-restricted memory T cells inhibit expansion of a nonprotective MHC class Ib (H2-M3)-restricted memory response.
Nature immunology 2004;5(2):159-68.
2003: Messingham Kelly A Nordyke; Badovinac Vladimir P; Harty John T
Deficient anti-listerial immunity in the absence of perforin can be restored by increasing memory CD8+ T cell numbers.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):4254-62.
2003: Badovinac Vladimir P; Messingham Kelly A Nordyke; Hamilton Sara E; Harty John T
Regulation of CD8+ T cells undergoing primary and secondary responses to infection in the same host.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(10):4933-42.
2003: Badovinac Vladimir P; Hamilton Sara E; Harty John T
Viral infection results in massive CD8+ T cell expansion and mortality in vaccinated perforin-deficient mice.
Immunity 2003;18(4):463-74.
2003: Badovinac Vladimir P; Harty John T
Memory lanes.
Nature immunology 2003;4(3):212-3.
2002: Hamilton Sara E; Harty John T
Quantitation of CD8+ T cell expansion, memory, and protective immunity after immunization with peptide-coated dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):4936-44.
2002: Badovinac Vladimir P; Porter Brandon B; Harty John T
Programmed contraction of CD8(+) T cells after infection.
Nature immunology 2002;3(7):619-26.
2002: Harty John T; Badovinac Vladimir P
Influence of effector molecules on the CD8(+) T cell response to infection.
Current opinion in immunology 2002;14(3):360-5.
2002: Badovinac Vladimir P; Harty John T
CD8(+) T-cell homeostasis after infection: setting the 'curve'.
Microbes and infection / Institut Pasteur 2002;4(4):441-7.
2002: Tvinnereim Amy R; Hamilton Sara E; Harty John T
CD8(+)-T-cell response to secreted and nonsecreted antigens delivered by recombinant Listeria monocytogenes during secondary infection.
Infection and immunity 2002;70(1):153-62.
2001: Hamilton S E; Tvinnereim A R; Harty J T
Listeria monocytogenes infection overcomes the requirement for CD40 ligand in exogenous antigen presentation to CD8(+) T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):5603-9.
2001: Wilson R L; Tvinnereim A R; Jones B D; Harty J T
Identification of Listeria monocytogenes in vivo-induced genes by fluorescence-activated cell sorting.
Infection and immunity 2001;69(8):5016-24.
2001: Badovinac V P; Harty J T
Detection and analysis of antigen-specific CD8+ T cells.
Immunologic research 2001;24(3):325-32.
2000: Badovinac V P; Tvinnereim A R; Harty J T
Regulation of antigen-specific CD8+ T cell homeostasis by perforin and interferon-gamma.
Science (New York, N.Y.) 2000;290(5495):1354-8.
2000: Badovinac V P; Corbin G A; Harty J T
Cutting edge: OFF cycling of TNF production by antigen-specific CD8+ T cells is antigen independent.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(10):5387-91.
2000: White D W; Badovinac V P; Fan X; Harty J T
Adaptive immunity against Listeria monocytogenes in the absence of type I tumor necrosis factor receptor p55.
Infection and immunity 2000;68(8):4470-6.
2000: White D W; Badovinac V P; Kollias G; Harty J T
Cutting edge: antilisterial activity of CD8+ T cells derived from TNF-deficient and TNF/perforin double-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(1):5-9.
2000: Badovinac V P; Harty J T
Adaptive immunity and enhanced CD8+ T cell response to Listeria monocytogenes in the absence of perforin and IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(12):6444-52.
2000: Myung P S; Clements J L; White D W; Malik Z A; Cowdery J S; Allen L H; Harty J T; Kusner D J; Koretzky G A
In vitro and in vivo macrophage function can occur independently of SLP-76.
International immunology 2000;12(6):887-97.
2000: Badovinac V P; Harty J T
Intracellular staining for TNF and IFN-gamma detects different frequencies of antigen-specific CD8(+) T cells.
Journal of immunological methods 2000;238(1-2):107-17.
2000: Tvinnereim A R; Harty J T
CD8(+) T-cell priming against a nonsecreted Listeria monocytogenes antigen is independent of the antimicrobial activities of gamma interferon.
Infection and immunity 2000;68(4):2196-204.
2000: Wilson R L; White D W; Harty J T
Transient expression of bacterial gene fragments in eukaryotic cells: implications for CD8(+) T cell epitope analysis.
Journal of immunological methods 2000;234(1-2):137-47.
2000: Harty J T; Tvinnereim A R; White D W
CD8+ T cell effector mechanisms in resistance to infection.
Annual review of immunology 2000;18():275-308.
1999: Harty J T; White D
A knockout approach to understanding CD8+ cell effector mechanisms in adaptive immunity to Listeria monocytogenes.
Immunobiology 1999;201(2):196-204.
1999: Harty J T; Bevan M J
Responses of CD8(+) T cells to intracellular bacteria.
Current opinion in immunology 1999;11(1):89-93.
1999: White D W; MacNeil A; Busch D H; Pilip I M; Pamer E G; Harty J T
Perforin-deficient CD8+ T cells: in vivo priming and antigen-specific immunity against Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(2):980-8.
1998: Krieg A M; Love-Homan L; Yi A K; Harty J T
CpG DNA induces sustained IL-12 expression in vivo and resistance to Listeria monocytogenes challenge.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2428-34.
1998: Jensen V B; Harty J T; Jones B D
Interactions of the invasive pathogens Salmonella typhimurium, Listeria monocytogenes, and Shigella flexneri with M cells and murine Peyer's patches.
Infection and immunity 1998;66(8):3758-66.
1998: White D W; Harty J T
Perforin-deficient CD8+ T cells provide immunity to Listeria monocytogenes by a mechanism that is independent of CD95 and IFN-gamma but requires TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(2):898-905.
1996: White D W; Wilson R L; Harty J T
CD8+ T cells in intracellular bacterial infections of mice.
Research in immunology 1996;147(8-9):519-24.
1996: Harty J T; Bevan M J
CD8 T-cell recognition of macrophages and hepatocytes results in immunity to Listeria monocytogenes.
Infection and immunity 1996;64(9):3632-40.
1995: Harty J T; Bevan M J
Specific immunity to Listeria monocytogenes in the absence of IFN gamma.
Immunity 1995;3(1):109-17.
1995: Harty J T; Pamer E G
CD8 T lymphocytes specific for the secreted p60 antigen protect against Listeria monocytogenes infection.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(9):4642-50.

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