Tsunemi Hasegawa

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Kikuchi Kunio; Umehara Takuya; Nishikawa Fumiko; Fukuda Kotaro; Hasegawa Tsunemi; Nishikawa Satoshi
Increased inhibitory ability of conjugated RNA aptamers against the HCV IRES.
Suzuki Ryuichiro; Fujimoto Zui; Ito Shigeyasu; Kawahara Shun-Ichi; Kaneko Satoshi; Taira Kazunari; Hasegawa Tsunemi; Kuno Atsushi
Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86.
Tsuchiya Wataru; Hasegawa Tsunemi
Molecular recognition of tryptophan tRNA by tryptophanyl-tRNA synthetase from Aeropyrum pernix K1.

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2009: Kikuchi Kunio; Umehara Takuya; Nishikawa Fumiko; Fukuda Kotaro; Hasegawa Tsunemi; Nishikawa Satoshi
Increased inhibitory ability of conjugated RNA aptamers against the HCV IRES.
Biochemical and biophysical research communications 2009;386(1):118-23.
2009: Suzuki Ryuichiro; Fujimoto Zui; Ito Shigeyasu; Kawahara Shun-Ichi; Kaneko Satoshi; Taira Kazunari; Hasegawa Tsunemi; Kuno Atsushi
Crystallographic snapshots of an entire reaction cycle for a retaining xylanase from Streptomyces olivaceoviridis E-86.
Journal of biochemistry 2009;146(1):61-70.
2009: Tsuchiya Wataru; Hasegawa Tsunemi
Molecular recognition of tryptophan tRNA by tryptophanyl-tRNA synthetase from Aeropyrum pernix K1.
Journal of biochemistry 2009;145(5):635-41.
2009: Hemmi Hikaru; Kuno Atsushi; Ito Shigeyasu; Suzuki Ryuichiro; Hasegawa Tsunemi; Hirabayashi Jun
NMR studies on the interaction of sugars with the C-terminal domain of an R-type lectin from the earthworm Lumbricus terrestris.
The FEBS journal 2009;276(7):2095-105.
2009: Suzuki Ryuichiro; Kuno Atsushi; Hasegawa Tsunemi; Hirabayashi Jun; Kasai Ken Ichi; Momma Mitsuru; Fujimoto Zui
Sugar-complex structures of the C-half domain of the galactose-binding lectin EW29 from the earthworm Lumbricus terrestris.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 1):49-57.
2008: Fukuda Kotaro; Watanabe Tomoya; Tokisue Takashi; Tsujita Tadayuki; Nishikawa Satoshi; Hasegawa Tsunemi; Seya Tsukasa; Matsumoto Misako
Modulation of double-stranded RNA recognition by the N-terminal histidine-rich region of the human toll-like receptor 3.
The Journal of biological chemistry 2008;283(33):22787-94.
2008: Konno Keisuke; Fujita Syusuke; Iizuka Mana; Nishikawa Satoshi; Hasegawa Tsunemi; Fukuda Kotaro
Isolation and characterization of RNA aptamers specific for the HCV minus-IRES domain I.
Nucleic acids symposium series (2004) 2008;(52):493-4.
2008: Fukuda Kotaro; Toyokawa Yohei; Kikuchi Kunio; Konno Keisuke; Ishihara Rie; Fukazawa Chisato; Nishikawa Satoshi; Hasegawa Tsunemi
Isolation of RNA aptamers specific for the 3' X tail of HCV.
Nucleic acids symposium series (2004) 2008;(52):205-6.
2008: Tokisue Takashi; Watanabe Tomoya; Tsujita Tadayuki; Nishikawa Satoshi; Hasegawa Tsunemi; Seya Tsukasa; Matsumoto Misako; Fukuda Kotaro
Significance of the N-terminal histidine-rich region for the function of the human toll-like receptor 3 ectodomain.
Nucleic acids symposium series (2004) 2008;(52):203-4.
2007: Watanabe Tomoya; Tokisue Takashi; Tsujita Tadayuki; Matsumoto Misako; Seya Tsukasa; Nishikawa Satoshi; Hasegawa Tsunemi; Fukuda Kotaro
N-terminal binding site in the human toll-like receptor 3 ectodomain.
Nucleic acids symposium series (2004) 2007;(51):405-6.
2007: Konno Keisuke; Nishikawa Satoshi; Hasegawa Tsunemi; Fukuda Kotaro
Isolation of RNA aptamers specific for the HCV minus-IRES domain I.
Nucleic acids symposium series (2004) 2007;(51):393-4.
2007: Tsuchiya Wataru; Kimura Manami; Hasegawa Tsunemi
Determination of phenylalanine tRNA recognition sites by phenylalanyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids symposium series (2004) 2007;(51):367-8.
2006: Taki Masumi; Kuno Atsushi; Matoba Shinsuke; Kobayashi Yuki; Futami Junichiro; Murakami Hiroshi; Suga Hiroaki; Taira Kazunari; Hasegawa Tsunemi; Sisido Masahiko
Leucyl/Phenylalanyl-tRNA-protein transferase-mediated chemoenzymatic coupling of N-terminal Arg/Lys units in post-translationally processed proteins with non-natural amino acids.
Chembiochem : a European journal of chemical biology 2006;7(11):1676-9.
2006: Watanabe Tomoya; Ito Kiyoharu; Matsumoto Misako; Seya Tsukasa; Nishikawa Satoshi; Hasegawa Tsunemi; Fukuda Kotaro
Isolation of RNA aptamers against human Toll-like receptor 3 ectodomain.
Nucleic acids symposium series (2004) 2006;(50):251-2.
2006: Fukuda Kotaro; Tsujita Tadayuki; Matsumoto Misako; Seya Tsukasa; Sakiyama Hiroshi; Nishikawa Fumiko; Nishikawa Satoshi; Hasegawa Tsunemi
Analysis of the interaction between human TLR3 ectodomain and nucleic acids.
Nucleic acids symposium series (2004) 2006;(50):249-50.
2005: Iwaki Jun; Suzuki Ryuichiro; Fujimoto Zui; Momma Mitsuru; Kuno Atsushi; Hasegawa Tsunemi
Overexpression, purification and crystallization of tyrosyl-tRNA synthetase from the hyperthermophilic archaeon Aeropyrum pernix K1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 11):1003-5.
2005: Umehara Takuya; Fukuda Kotaro; Nishikawa Fumiko; Kohara Michinori; Hasegawa Tsunemi; Nishikawa Satoshi
Rational design of dual-functional aptamers that inhibit the protease and helicase activities of HCV NS3.
Journal of biochemistry 2005;137(3):339-47.
2005: Nagatoyo Yukari; Iwaki Jun; Suzuki Satoko; Kuno Atsushi; Hasegawa Tsunemi
Molecular recognition of histidine tRNA by histidyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids symposium series (2004) 2005;(49):307-8.
2005: Okamoto Koji; Kuno Atsushi; Hasegawa Tsunemi
Recognition sites of glycine tRNA for glycyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids symposium series (2004) 2005;(49):299-300.
2005: Kikuchi Kunio; Umehara Takuya; Fukuda Kotaro; Kuno Atsushi; Hasegawa Tsunemi; Nishikawa Satoshi
A hepatitis C virus (HCV) internal ribosome entry site (IRES) domain III-IV-targeted aptamer inhibits translation by binding to an apical loop of domain IIId.
Nucleic acids research 2005;33(2):683-92.
2004: Fukuda Kotaro; Umehara Takuya; Sekiya Satoru; Kunio Kikuchi; Hasegawa Tsunemi; Nishikawa Satoshi
An RNA ligand inhibits hepatitis C virus NS3 protease and helicase activities.
Biochemical and biophysical research communications 2004;325(3):670-5.
2004: Hemmi Hikaru; Kuno Atsushi; Ito Shigeyasu; Suzuki Ryuichiro; Kaneko Satoshi; Hasegawa Tsunemi; Hirabayashi Jun; Kasai Ken-Ichi
(1)H, (13)C, and (15)N chemical shift assignment of the C-terminal 15 kDa domain of a novel galactose-binding protein from the earthworm Lumbricus terrestris.
Journal of biomolecular NMR 2004;30(3):377-8.
2004: Suzuki Ryuichiro; Fujimoto Zui; Kuno Atsushi; Hirabayashi Jun; Kasai Ken-ichi; Hasegawa Tsunemi
Crystallization and preliminary X-ray crystallographic studies of the C-terminal domain of galactose-binding lectin EW29 from the earthworm Lumbricus terrestris.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 10):1895-6.
2004: Ito Shigeyasu; Kuno Atsushi; Suzuki Ryuichiro; Kaneko Satoshi; Kawabata Yasuyuki; Kusakabe Isao; Hasegawa Tsunemi
Rational affinity purification of native Streptomyces family 10 xylanase.
Journal of biotechnology 2004;110(2):137-42.
2004: Umehara Takuya; Fukuda Kotaro; Nishikawa Fumiko; Sekiya Satoru; Kohara Michinori; Hasegawa Tsunemi; Nishikawa Satoshi
Designing and analysis of a potent bi-functional aptamers that inhibit protease and helicase activities of HCV NS3.
Nucleic acids symposium series (2004) 2004;(48):195-6.
2004: Tsuchiya Wataru; Umehara Takuya; Kuno Atsushi; Hasegawa Tsunemi
Determination of tryptophan tRNA recognition sites for tryptophanyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids symposium series (2004) 2004;(48):185-6.
2004: Ichikawa Takayuki; Kuno Atsushi; Taki Masumi; Hohsaka Takahiro; Sisido Masahiko; Kaneko Satoshi; Taira Kazunari; Kobayashi Hideyuki; Hasegawa Tsunemi
Site-directed incorporation of non-natural amino acid into Streptomyces xylanase.
Nucleic acids symposium series (2004) 2004;(48):161-2.
2003: Ikeda Yutaka; Kawahara Shun-ichi; Taki Masumi; Kuno Atsushi; Hasegawa Tsunemi; Taira Kazunari
Synthesis of a novel histidine analogue and its efficient incorporation into a protein in vivo.
Protein engineering 2003;16(9):699-706.
2003: Hemmi Hikaru; Kuno Atsushi; Ito Shigeyasu; Kaneko Satoshi; Hasegawa Tsunemi
1H, 13C and 15N chemical shift assignment of xylan-binding domain from Streptomyces olivaceoviridis E-86 beta-xylanase.
Journal of biomolecular NMR 2003;27(1):91-2.
2003: Kikuchi Kunio; Umehara Takuya; Fukuda Kotaro; Hwang Joonsung; Kuno Atsushi; Hasegawa Tsunemi; Nishikawa Satoshi
RNA aptamers targeted to domain II of hepatitis C virus IRES that bind to its apical loop region.
Journal of biochemistry 2003;133(3):263-70.
2003: Kikuchi Kunio; Umehara Takuya; Fukuda Kotaro; Hwang Joonsung; Kuno Atsushi; Hasegawa Tsunemi; Nishikawa Satoshi
Structure-inhibition analysis of RNA aptamers that bind to HCV IRES.
Nucleic acids research. Supplement (2001) 2003;(3):291-2.
2003: Kuno Atsushi; Taki Masumi; Kaneko Satoshi; Taira Kazunari; Hasegawa Tsunemi
Leucyl/phenylalanyl (L/F)-tRNA-protein transferase-mediated N-terminal specific labelling of a protein in vitro.
Nucleic acids research. Supplement (2001) 2003;(3):259-60.
2003: Yokozawa Junji; Okamoto Koji; Kawarabayasi Yutaka; Kuno Atsushi; Hasegawa Tsunemi
Molecular recognition of proline tRNA by prolyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids research. Supplement (2001) 2003;(3):247-8.
2002: Kikuchi Kunio; Fukuda Kotaro; Umehara Takuya; Hwang Joonsung; Kuno Atsushi; Hasegawa Tsunemi; Nishikawa Satoshi
In vitro selection of RNA aptamers that bind to domain II of HCV IRES.
Nucleic acids research. Supplement (2001) 2002;(2):267-8.
2002: Iwaki Jun; Asahara Haruichi; Nagaoka Yoshiyuki; Yokozawa Junji; Umehara Takuya; Kawarabayasi Yutaka; Koyama Yoshinori; Sako Yoshihiko; Kuno Atsushi; Hasegawa Tsunemi
Differences in tyrosine tRNA identity between Escherichia coli and archaeon, Aeropyrum pernix K1.
Nucleic acids research. Supplement (2001) 2002;(2):225-6.
2002: Taki Masumi; Hohsaka Takahiro; Murakami Hiroshi; Kuno Atsushi; Hasegawa Tsunemi; Taira Kazunari; Sisido Masahiko
A novel fluorescent nonnatural amino acid that can be incorporated into a specific position of streptavidin.
Nucleic acids research. Supplement (2001) 2002;(2):203-4.
2002: Nagaoka Yoshiyuki; Yokozawa Junji; Umehara Takuya; Iwaki Jun; Okamoto Koji; Kawarabayasi Yutaka; Koyama Yoshinori; Sako Yoshihiko; Wakagi Takayoshi; Kuno Atsushi; Hasegawa Tsunemi
Molecular recognition of threonine tRNA by threonyl-tRNA synthetase from an extreme thermophilic archaeon, Aeropyrum pernix K1.
Nucleic acids research. Supplement (2001) 2002;(2):81-2.
2001: Yokozawa J; Nagaoka Y; Umehara T; Iwaki J; Kawarabayasi Y; Koyama Y; Sako Y; Wakagi T; Kuno A; Hasegawa T
Recognition of tRNA by aminoacyl-tRNA synthetase from hyperthermophilic archaea, Aeropyrum pernix K1.
Nucleic acids research. Supplement (2001) 2001;(1):117-8.
2000: Kuno A; Kaneko S; Ohtsuki H; Ito S; Fujimoto Z; Mizuno H; Hasegawa T; Taira K; Kusakabe I; Hayashi K
Novel sugar-binding specificity of the type XIII xylan-binding domain of a family F/10 xylanase from Streptomyces olivaceoviridis E-86.
FEBS letters 2000;482(3):231-6.
2000: Ishikura H; Nagaoka Y; Yokozawa J; Umehara T; Kuno A; Hasegawa T
Threonyl-tRNA synthetase of archaea: importance of the discriminator base in the aminoacylation of threonine tRNA.
Nucleic acids symposium series 2000;(44):83-4.
2000: Hasegawa T; Yokogawa T
Escherichia coli proline tRNA: structure and recognition sites for prolyl-tRNA synthetase.
Nucleic acids symposium series 2000;(44):7-8.
1998: Asahara H; Nameki N; Hasegawa T
In vitro selection of RNAs aminoacylated by Escherichia coli leucyl-tRNA synthetase.
Journal of molecular biology 1998;283(3):605-18.
1997: Nameki N; Tamura K; Asahara H; Hasegawa T
Recognition of tRNA(Gly) by three widely diverged glycyl-tRNA synthetases.
Journal of molecular biology 1997;268(3):640-7.
1997: Nameki N; Tamura K; Asahara H; Hasegawa T
Recognition of tRNA(Gly) by three widely diverged glycyl-tRNA synthetases: evolution of tRNA recognition.
Nucleic acids symposium series 1997;(37):123-4.
1996: Nameki N; Asahara H; Hasegawa T
Identity elements of Thermus thermophilus tRNA(Thr).
FEBS letters 1996;396(2-3):201-7.

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Tsunemi Hasegawa

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