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Kathryn Haskins

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Thomas Delong; Rocky L Baker; Jing He; Kathryn Haskins
Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes.
Kristen N Cordova; Kathryn Haskins; Van C Willis; V Michael Holers
A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.
Patrick S Hume; Kathryn Haskins; Jing He; Kristi S Anseth
Strategies to reduce dendritic cell activation through functional biomaterial design.

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All Publications

2013: Thomas Delong; Rocky L Baker; Jing He; Kathryn Haskins
Novel autoantigens for diabetogenic CD4 T cells in autoimmune diabetes.
Immunologic research 2013;55(1-3):167-72.
2013: Kristen N Cordova; Kathryn Haskins; Van C Willis; V Michael Holers
A citrullinated fibrinogen-specific T cell line enhances autoimmune arthritis in a mouse model of rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(4):1457-65.
2012: Patrick S Hume; Kathryn Haskins; Jing He; Kristi S Anseth
Strategies to reduce dendritic cell activation through functional biomaterial design.
Biomaterials 2012;33(14):3615-25.
2012: Rocky L Baker; Laurent Gapin; Thierry Mallevaey; Kathryn Haskins
T cells interact with T cells via CD40-CD154 to promote autoimmunity in type 1 diabetes.
European journal of immunology 2012;42(3):672-80.
2011: Kathryn Haskins; Anne Cooke
CD4 T cells and their antigens in the pathogenesis of autoimmune diabetes.
Current opinion in immunology 2011;23(6):739-45.
2011: Michael A Zimmerman; Kathryn Haskins; Brenda Bradley; Jessica Gilman; Fabia Gamboni-Robertson; Sonia C Flores
Autoimmune-mediated vascular injury occurs prior to sustained hyperglycemia in a murine model of type I diabetes mellitus.
The Journal of surgical research 2011;168(2):e195-202.
2010: Brian D Stadinski; Thomas Delong; Nichole Reisdorph; Richard Reisdorph; Roger L Powell; Michael Armstrong; Jon D Piganelli; Gene Barbour; Brenda Bradley; Frances Crawford; Philippa Marrack; Sushil K Mahata; John W Kappler; Kathryn Haskins
Chromogranin A is an autoantigen in type 1 diabetes.
Nature immunology 2010;11(3):225-31.
2009: Li Zhang; Jean M Jasinski; Masakazu Kobayashi; Bennett Davenport; Kelly Johnson; Howard Davidson; Maki Nakayama; Kathryn Haskins; George S Eisenbarth
Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains.
Journal of autoimmunity 2009;33(1):42-9.
2009: Daniel R Tonkin; Kathryn Haskins
Regulatory T cells enter the pancreas during suppression of type 1 diabetes and inhibit effector T cells and macrophages in a TGF-beta-dependent manner.
European journal of immunology 2009;39(5):1313-22.
2008: Rocky L Baker; David H Wagner; Kathryn Haskins
CD40 on NOD CD4 T cells contributes to their activation and pathogenicity.
Journal of autoimmunity 2008;31(4):385-92.
2008: Daniel R Tonkin; Jing He; Gene Barbour; Kathryn Haskins
Regulatory T cells prevent transfer of type 1 diabetes in NOD mice only when their antigen is present in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4516-22.
2008: Jing He; Kathryn Haskins
Pathogenicity of T helper 2 T-cell clones from T-cell receptor transgenic non-obese diabetic mice is determined by tumour necrosis factor-alpha.
Immunology 2008;123(1):108-17.
2007: Joseph Cantor; Kathryn Haskins
Recruitment and activation of macrophages by pathogenic CD4 T cells in type 1 diabetes: evidence for involvement of CCR8 and CCL1.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(9):5760-7.
2007: Mark R Nicolls; Kathryn Haskins; Sonia C Flores
Oxidant stress, immune dysregulation, and vascular function in type I diabetes.
Antioxidants & redox signaling 2007;9(7):879-89.
2007: Laney M Weber; Kirsten N Hayda; Kathryn Haskins; Kristi S Anseth
The effects of cell-matrix interactions on encapsulated beta-cell function within hydrogels functionalized with matrix-derived adhesive peptides.
Biomaterials 2007;28(19):3004-11.
2006: Laney M Weber; Jing He; Brenda Bradley; Kathryn Haskins; Kristi S Anseth
PEG-based hydrogels as an in vitro encapsulation platform for testing controlled beta-cell microenvironments.
Acta biomaterialia 2006;2(1):1-8.
2005: Joseph Cantor; Kathryn Haskins
Effector function of diabetogenic CD4 Th1 T cell clones: a central role for TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7738-45.
2005: Xiaofeng Ling; Adela Cota-Gomez; Natalia C Flores; Daniel Hernandez-Saavedra; Joe M McCord; John C Marecki; Kathryn Haskins; Marcia McDuffie; Katherine Powers; Jennifer Kench; Masahiko Oka; Ivan F McMurtry; Sonia C Flores
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice.
Free radical biology & medicine 2005;39(8):1089-98.
2004: Mary E Pauza; Cathleen Dobbs; Jing He; Tricia Patterson; Steven Wagner; Brian S Anobile; Brenda J Bradley; David Lo; Kathryn Haskins
T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes.
Diabetes 2004;53(4):978-88.
2004: Kathryn Haskins
T-cell receptor transgenic (TCR-Tg) mice from two diabetogenic CD4+ islet-antigen-specific T-cell clones.
Journal of autoimmunity 2004;22(2):107-9.
2004: Kathryn Haskins; Jennifer Kench; Katherine Powers; Brenda Bradley; Subbiah Pugazhenthi; Jane E B Reusch; Marcia McDuffie
Role for oxidative stress in the regeneration of islet beta cells?
Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2004;52(1):45-9.
2003: Kathryn Haskins; Brenda Bradley; Katherine Powers; Valerie A Fadok; Sonia Flores; Xiaofeng Ling; Subbiah Pugazhenthi; Jane E B Reusch; Jennifer Kench
Oxidative stress in type 1 diabetes.
Annals of the New York Academy of Sciences 2003;1005():43-54.
2003: Thomas Stratmann; Natalia Martin-Orozco; Valérie Mallet-Designe; Laurent Poirot; Dorian B McGavern; Grigoriy Losyev; Cathleen Dobbs; Michael B A Oldstone; Kenji Yoshida; Hitoshi Kikutani; Diane Mathis; Christophe Benoist; Kathryn Haskins; Luc Teyton
Susceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.
The Journal of clinical investigation 2003;112(6):902-14.
2003: Gisela M Vaitaitis; Michelle Poulin; Richard J Sanderson; Kathryn Haskins; David H Wagner
Cutting edge: CD40-induced expression of recombination activating gene (RAG) 1 and RAG2: a mechanism for the generation of autoaggressive T cells in the periphery.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(7):3455-9.
2002: Kenji Yoshida; Tracy Martin; Ken Yamamoto; Cathleen Dobbs; Christian Münz; Nobuhiro Kamikawaji; Naoko Nakano; Hans-Georg Rammensee; Takehiko Sasazuki; Kathryn Haskins; Hitoshi Kikutani
Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.
International immunology 2002;14(12):1439-47.
2002: David H Wagner; Gisela M Vaitaitis; Richard J Sanderson; Michelle Poulin; Cathleen Dobbs; Kathryn Haskins
Expression of CD40 identifies a unique pathogenic T cell population in type 1 diabetes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(6):3782-7.
2002: Jon D Piganelli; Sonia C Flores; Coral Cruz; Jeffrey Koepp; Ines Batinic-Haberle; James D Crapo; Brian Day; Remy Kachadourian; Rebekah Young; Brenda Bradley; Kathryn Haskins
A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone.
Diabetes 2002;51(2):347-55.
2001: Cathleen Dobbs; Kathryn Haskins
Comparison of a T cell clone and of T cells from a TCR transgenic mouse: TCR transgenic T cells specific for self-antigen are atypical.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2495-504.
2001: Kathryn Haskins; M Atkinson
Prediction of diabetes and response to therapy in individual animals: are there lessons for man? Report on the JDF/Snow Mountain Meeting, 5-7 October 2000, Winter Park, CO, USA.
Journal of autoimmunity 2001;16(1):15-9.
2000: B Bergman; James L McManaman; Kathryn Haskins
Biochemical characterization of a beta cell membrane fraction antigenic for autoreactive T cell clones.
Journal of autoimmunity 2000;14(4):343-51.
2000: Michelle Poulin; Kathryn Haskins
Induction of diabetes in nonobese diabetic mice by Th2 T cell clones from a TCR transgenic mouse.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(6):3072-8.
2000: Jon D Piganelli; Michelle Poulin; T Martin; J P Allison; Kathryn Haskins
Cytotoxic T lymphocyte antigen 4 (CD152) regulates self-reactive T cells in BALB/c but not in the autoimmune NOD mouse.
Journal of autoimmunity 2000;14(2):123-31.
2000: judith rosmalen; T Martin; Cathleen Dobbs; Jane S A Voerman; Hemmo Drexhage; Kathryn Haskins; Pieter J M Leenen
Subsets of macrophages and dendritic cells in nonobese diabetic mouse pancreatic inflammatory infiltrates: correlation with the development of diabetes.
Laboratory investigation; a journal of technical methods and pathology 2000;80(1):23-30.
1999: Kathryn Haskins
T cell receptor gene usage in autoimmune diabetes.
International reviews of immunology 1999;18(1-2):61-81.
1998: J D Peterson; R Berg; Jon D Piganelli; Michelle Poulin; Kathryn Haskins
Analysis of leukocytes recruited to the pancreas by diabetogenic T cell clones.
Cellular immunology 1998;189(2):92-8.
1998: Jon D Piganelli; T Martin; Kathryn Haskins
Splenic macrophages from the NOD mouse are defective in the ability to present antigen.
Diabetes 1998;47(8):1212-8.
1997: B Bergman; Kathryn Haskins
Autoreactive T-cell clones from the nonobese diabetic mouse.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;214(1):41-8.
1996: Kathryn Haskins; Dale R Wegmann
Diabetogenic T-cell clones.
Diabetes 1996;45(10):1299-305.
1996: J D Peterson; Kathryn Haskins
Transfer of diabetes in the NOD-scid mouse by CD4 T-cell clones. Differential requirement for CD8 T-cells.
Diabetes 1996;45(3):328-36.
1995: J D Peterson; B Pike; A Dallas-Pedretti; Kathryn Haskins
Induction of diabetes with islet-specific T-cell clones is age dependent.
Immunology 1995;85(3):455-60.
1995: A Dallas-Pedretti; M McDuffie; Kathryn Haskins
A diabetes-associated T-cell autoantigen maps to a telomeric locus on mouse chromosome 6.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(5):1386-90.
1994: J D Peterson; B Pike; M McDuffie; Kathryn Haskins
Islet-specific T cell clones transfer diabetes to nonobese diabetic (NOD) F1 mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(6):2800-6.
1994: B Bergman; Kathryn Haskins
Islet-specific T-cell clones from the NOD mouse respond to beta-granule antigen.
Diabetes 1994;43(2):197-203.
1993: J D Katz; B Wang; Kathryn Haskins; Christophe Benoist; Diane Mathis
Following a diabetogenic T cell from genesis through pathogenesis.
Cell 1993;74(6):1089-100.
1993: R G Gill; Kathryn Haskins
Molecular mechanisms underlying diabetes and other autoimmune diseases.
Immunology today 1993;14(2):49-51.
1992: B J Bradley; Kathryn Haskins; F G La Rosa; K J Lafferty
CD8 T cells are not required for islet destruction induced by a CD4+ islet-specific T-cell clone.
Diabetes 1992;41(12):1603-8.
1992: Dale R Wegmann; M Norbury-Glaser; B Bergman; Kathryn Haskins
High efficiency presentation of TNP-conjugated islet antigen to islet-specific T cells by a hybrid B cell line expressing TNP-specific surface Ig.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(1):77-82.
1990: P Supon; P Stecha; Kathryn Haskins
Anti-islet cell antibodies from NOD mice.
Diabetes 1990;39(11):1366-72.
1990: Kathryn Haskins; M McDuffie
Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone.
Science (New York, N.Y.) 1990;249(4975):1433-6.
1990: B J Bradley; Y Y Wang; K J Lafferty; Kathryn Haskins
In vivo activity of an islet-reactive T-cell clone.
Journal of autoimmunity 1990;3(4):449-56.
1989: Kathryn Haskins; M Portas; B Bergman; K Lafferty; B Bradley
Pancreatic islet-specific T-cell clones from nonobese diabetic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(20):8000-4.
1989: J Böhme; Kathryn Haskins; P Stecha; W van Ewijk; Marianne LeMeur; P Gerlinger; Christophe Benoist; Diane Mathis
Transgenic mice with I-A on islet cells are normoglycemic but immunologically intolerant.
Science (New York, N.Y.) 1989;244(4909):1179-83.
1988: Kathryn Haskins; M Portas; B Bradley; Dale R Wegmann; K Lafferty
T-lymphocyte clone specific for pancreatic islet antigen.
Diabetes 1988;37(10):1444-8.