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Claudine Haslam

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Gerard M P Giblin; Celestine T O'Shaughnessy; Alan Naylor; William L Mitchell; Andrew J Eatherton; Brian P Slingsby; D Anthony Rawlings; Paul Goldsmith; Andrew J Brown; Claudine Haslam; Nicholas M Clayton; Alex W Wilson; Iain P Chessell; Andrew R Wittington; Richard Green
Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.
Sharon Bingham; Paul J Beswick; Chas Bountra; Terry Brown; Ian B Campbell; Iain P Chessell; Nick Clayton; Sue D Collins; Philip T Davey; Helen Goodland; Norman Gray; Claudine Haslam; Jonathan P Hatcher; A Jackie Hunter; Fiona Lucas; Graham Murkitt; Alan Naylor; Elizabeth Pickup; Becky Sargent; Scott G Summerfield; Alexander Stevens; Sharon C Stratton; Joanne Wiseman
The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central sensitization.
Paul J Beswick; Sharon Bingham; Chas Bountra; Terry Brown; Kerry Browning; Ian Campbell; Iain P Chessell; Nick Clayton; Sue Collins; John Corfield; Stephen Guntrip; Claudine Haslam; Paul Lambeth; Fiona Lucas; Neil Mathews; Graham Murkit; Alan Naylor; Neil Pegg; Elizabeth Pickup; Hazel Player; Helen Price; Alexander Stevens; Sharon Stratton; Joanne Wiseman
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.

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2007: Gerard M P Giblin; Celestine T O'Shaughnessy; Alan Naylor; William L Mitchell; Andrew J Eatherton; Brian P Slingsby; D Anthony Rawlings; Paul Goldsmith; Andrew J Brown; Claudine Haslam; Nicholas M Clayton; Alex W Wilson; Iain P Chessell; Andrew R Wittington; Richard Green
Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.
Journal of medicinal chemistry 2007;50(11):2597-600.
2005: Sharon Bingham; Paul J Beswick; Chas Bountra; Terry Brown; Ian B Campbell; Iain P Chessell; Nick Clayton; Sue D Collins; Philip T Davey; Helen Goodland; Norman Gray; Claudine Haslam; Jonathan P Hatcher; A Jackie Hunter; Fiona Lucas; Graham Murkitt; Alan Naylor; Elizabeth Pickup; Becky Sargent; Scott G Summerfield; Alexander Stevens; Sharon C Stratton; Joanne Wiseman
The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central sensitization.
The Journal of pharmacology and experimental therapeutics 2005;312(3):1161-9.
2004: Paul J Beswick; Sharon Bingham; Chas Bountra; Terry Brown; Kerry Browning; Ian Campbell; Iain P Chessell; Nick Clayton; Sue Collins; John Corfield; Stephen Guntrip; Claudine Haslam; Paul Lambeth; Fiona Lucas; Neil Mathews; Graham Murkit; Alan Naylor; Neil Pegg; Elizabeth Pickup; Hazel Player; Helen Price; Alexander Stevens; Sharon Stratton; Joanne Wiseman
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors.
Bioorganic & medicinal chemistry letters 2004;14(21):5445-8.