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Paul Hassoun

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Bo S Kim; Ahmad Parniani; R Scott Stephens; Leonid Serebreni; Thomas Sussan; Lan Wang; Laurent Boyer; Mahendra Damarla; Omar Hamdan; Paul M Hassoun; rachel damico
Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis.
Marius M Hoeper; David Lawrence; Nicholas W Morrell; Andrew J Peacock; Deborah A Quinn; Toru Satoh; Gérald Simonneau; Victor F Tapson; Fernando Torres; Robyn J Barst; Robert C Bourge; Jeremy Feldman; Adaani E Frost; Nazzareno Galié; Miguel Angel Gómez-Sánchez; Friedrich Grimminger; Ekkehard Grünig; Paul M Hassoun; Hossein-Ardeschir Ghofrani
Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study.
Abdelkader Mahammedi; Alexander Oshmyansky; Paul M Hassoun; David R Thiemann; Stanley S Siegelman
Pulmonary artery measurements in pulmonary hypertension: the role of computed tomography.

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2013: Bo S Kim; Ahmad Parniani; R Scott Stephens; Leonid Serebreni; Thomas Sussan; Lan Wang; Laurent Boyer; Mahendra Damarla; Omar Hamdan; Paul M Hassoun; rachel damico
Xanthine oxidoreductase is a critical mediator of cigarette smoke-induced endothelial cell DNA damage and apoptosis.
Free radical biology & medicine 2013;60():336-46.
2013: Marius M Hoeper; David Lawrence; Nicholas W Morrell; Andrew J Peacock; Deborah A Quinn; Toru Satoh; Gérald Simonneau; Victor F Tapson; Fernando Torres; Robyn J Barst; Robert C Bourge; Jeremy Feldman; Adaani E Frost; Nazzareno Galié; Miguel Angel Gómez-Sánchez; Friedrich Grimminger; Ekkehard Grünig; Paul M Hassoun; Hossein-Ardeschir Ghofrani
Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study.
Circulation 2013;127(10):1128-38.
2013: Abdelkader Mahammedi; Alexander Oshmyansky; Paul M Hassoun; David R Thiemann; Stanley S Siegelman
Pulmonary artery measurements in pulmonary hypertension: the role of computed tomography.
Journal of thoracic imaging 2013;28(2):96-103.
2013: Paul M Hassoun; John Lawrence; Christian Meier; Evangelos Michelakis; Omar Minai; Gail Moreschi; Sylvia Nikkho; Paula Rinaldi; Erika B Rosenzweig; John Teeter; Ardeshir H Ghofrani; Ronald J Oudiz
Updating clinical endpoint definitions.
Pulmonary circulation 2013;3(1):206-16.
2013: Stephen C Mathai; Paul M Hassoun
Drs. Mathai and Hassoun reply.
The Journal of rheumatology 2013;40(1):91.
2013: Monda L Shehata; Jan Skrok; Tamer A Basha; David A Bluemke; Danielle Boyce; Reda E Girgis; Ahmed A Harouni; Paul M Hassoun; Noah Lechtzin; João A C Lima; Stephen C Mathai; Nael F Osman; Jens Vogel-Claussen
Regional and global biventricular function in pulmonary arterial hypertension: a cardiac MR imaging study.
Radiology 2013;266(1):114-22.
2012: Hala El Chami; Paul M Hassoun
Immune and inflammatory mechanisms in pulmonary arterial hypertension.
Progress in cardiovascular diseases 2012;55(2):218-28.
2012: Franco RAFAEL D'Alessio; Yoshiki Eto; Daniel C Files; Brian T Garibaldi; Paul M Hassoun; Jason R Mock; David B Pearse; SEKHAR POTHIREDDY; Jackie V Rodriguez; VENKATARAMANA SIDHAYE; Kenji Tsushima; Adam T Waickman; Neil R Aggarwal; Claudia R Avalos; Michael T Crow; Landon S King
Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(5):2234-45.
2012: rachel damico; Javier J Zulueta; Paul M Hassoun
Pulmonary endothelial cell NOX.
American journal of respiratory cell and molecular biology 2012;47(2):129-39.
2012: Stephen C Mathai; Paul M Hassoun
Pulmonary arterial hypertension in connective tissue diseases.
Heart failure clinics 2012;8(3):413-25.
2012: Paul M Hassoun; Serge Adnot
Update in pulmonary vascular diseases 2011.
American journal of respiratory and critical care medicine 2012;185(11):1177-82.
2012: Jan Skrok; Ari L Zaiman; David A Bluemke; Danielle Boyce; Reda E Girgis; Paul M Hassoun; Noah Lechtzin; João A C Lima; Stephen C Mathai; James OTIS Mudd; Monda L Shehata; Jens Vogel-Claussen
Pulmonary arterial hypertension: MR imaging-derived first-pass bolus kinetic parameters are biomarkers for pulmonary hemodynamics, cardiac function, and ventricular remodeling.
Radiology 2012;263(3):678-87.
2012: Todd Matthew Kolb; Paul M Hassoun
Right ventricular dysfunction in chronic lung disease.
Cardiology clinics 2012;30(2):243-56.
2012: Paul M Hassoun
Drumming up prognostic significance in a heartbeat in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2012;185(4):354-5.
2012: Ryan J Tedford; David R Thiemann; Vojtech Melenovsky; Oscar Horacio Cingolani; Reda E Girgis; Paul M Hassoun; David J Lederer; Stephen C Mathai; James OTIS Mudd; Margaret M Redfield; Stuart D Russell; David A Kass
Pulmonary capillary wedge pressure augments right ventricular pulsatile loading.
Circulation 2012;125(2):289-97.
2012: Chris Cheadle; JINSHUI FAN; Reda E Girgis; Dmitry N Grigoryev; Sangjucta Barkataki; Kathleen C Barnes; Alan E Berger; Meher Boorgula; Laura K Hummers; Roger Johns; Stephen C Mathai; A MICHAEL MCDEVITT; Yumiko Sugawara; Tonya N Watkins; Fredrick M Wigley; Ari L Zaiman; Paul M Hassoun
Erythroid-specific transcriptional changes in PBMCs from pulmonary hypertension patients.
PloS one 2012;7(4):e34951.
2011: Ari L Zaiman; Hunter C Champion; rachel damico; Hazim El-Haddad; D Clark Files; Marc K Halushka; Paul M Hassoun; Laura Johnston; Priya Kesari; Richard N Kitsis; Shehzin Mozammel; Allen C Myers; Chang-Fu Peng; Larissa A Shimoda; Mara Swaim; Alan Thoms-Chesley; Michael T Crow
A critical role for the protein apoptosis repressor with caspase recruitment domain in hypoxia-induced pulmonary hypertension.
Circulation 2011;124(23):2533-42.
2011: Stephen C Mathai; James OTIS Mudd; Christopher Sibley; Ryan J Tedford; Ari L Zaiman; Danielle Boyce; Micah R Fisher; Paul R Forfia; Reda E Girgis; Traci Housten; Laura K Hummers; Noah Lechtzin; Paul M Hassoun
Tricuspid annular plane systolic excursion is a robust outcome measure in systemic sclerosis-associated pulmonary arterial hypertension.
The Journal of rheumatology 2011;38(11):2410-8.
2011: Jens Vogel-Claussen; David A Bluemke; Danielle Boyce; Reda E Girgis; Noah Lechtzin; João A C Lima; Dirk Lossnitzer; Stephen C Mathai; Monda L Shehata; Sukhminder Singh; Jan Skrok; Paul M Hassoun
Increased right ventricular Septomarginal trabeculation mass is a novel marker for pulmonary hypertension: comparison with ventricular mass index and right ventricular mass.
Investigative radiology 2011;46(9):567-75.
2011: Paul M Hassoun
Pulmonary arterial hypertension in china: promising news and some surprises.
Chest 2011;140(2):276-8.
2011: Todd Matthew Kolb; rachel damico; Paul M Hassoun
Linking new and old concepts: inflammation meets the Warburg phenomenon in pulmonary arterial hypertension.
Journal of molecular medicine (Berlin, Germany) 2011;89(8):729-32.
2011: Jérôme Le Pavec; Noah Lechtzin; Stephen C Mathai; Gérald Simonneau; Olivier Sitbon; Ari L Zaiman; Reda E Girgis; Marc Humbert; Laura K Hummers; David Launay; Paul M Hassoun
Systemic sclerosis-related pulmonary hypertension associated with interstitial lung disease: impact of pulmonary arterial hypertension therapies.
Arthritis and rheumatism 2011;63(8):2456-64.
2011: Arantza Campo; H Chami; Reda E Girgis; T Housten; Laura K Hummers; J Le Pavec; Noah Lechtzin; Stephen C Mathai; Ari L Zaiman; D Boyce; Paul M Hassoun
Outcomes of hospitalisation for right heart failure in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;38(2):359-67.
2011: Steven M Kawut; David J Lederer; Harold I Palevsky; Wendy S Post; Kari E Roberts; Erika B Rosenzweig; Daichi Shimbo; Russell P Tracy; Emilia Bagiella; R Graham Barr; Reda E Girgis; Paul M Hassoun; Nicholas S Hill; Evelyn M Horn
Randomized clinical trial of aspirin and simvastatin for pulmonary arterial hypertension: ASA-STAT.
Circulation 2011;123(25):2985-93.
2011: Stephen C Mathai; Paul M Hassoun
Pulmonary arterial hypertension associated with systemic sclerosis.
Expert review of respiratory medicine 2011;5(2):267-79.
2011: Paul M Hassoun; rachel damico
Moving beyond the "Allegory of the Cave" in the assessment of pulmonary arterial hypertension.
Journal of applied physiology (Bethesda, Md. : 1985) 2011;110(4):871-2.
2011: Jérôme Le Pavec; David Launay; Stephen C Mathai; Paul M Hassoun; Marc Humbert
Scleroderma lung disease.
Clinical reviews in allergy & immunology 2011;40(2):104-16.
2011: Steven M Kawut; Emilia Bagiella; Daichi Shimbo; David J Lederer; Nadine Al-Naamani; Kari E Roberts; R Graham Barr; Wendy S Post; Evelyn M Horn; Russell Tracy; Paul M Hassoun; Reda E Girgis
Rationale and design of a phase II clinical trial of aspirin and simvastatin for the treatment of pulmonary arterial hypertension: ASA-STAT.
Contemporary clinical trials 2011;32(2):280-7.
2011: rachel damico; Tiffany Simms; Bo S Kim; Zenar Tekeste; Henry Amankwan; Mahendra Damarla; Paul M Hassoun
p53 mediates cigarette smoke-induced apoptosis of pulmonary endothelial cells: inhibitory effects of macrophage migration inhibitor factor.
American journal of respiratory cell and molecular biology 2011;44(3):323-32.
2011: Paul M Hassoun
Lung involvement in systemic sclerosis.
Presse médicale (Paris, France : 1983) 2011;40(1 Pt 2):e3-e17.
2011: Monda L Shehata; Dirk Lossnitzer; Jan Skrok; Danielle Boyce; Noah Lechtzin; Stephen C Mathai; Reda E Girgis; Nael F Osman; João A C Lima; David A Bluemke; Paul M Hassoun; Jens Vogel-Claussen
Myocardial delayed enhancement in pulmonary hypertension: pulmonary hemodynamics, right ventricular function, and remodeling.
AJR. American journal of roentgenology 2011;196(1):87-94.
2011: Jens Vogel-Claussen; Jan Skrok; Monda L Shehata; Sukhminder Singh; Christopher Sibley; Danielle M Boyce; Noah Lechtzin; Reda E Girgis; Stephen C Mathai; Thomas A Goldstein; Jie Zheng; João A C Lima; David A Bluemke; Paul M Hassoun
Right and left ventricular myocardial perfusion reserves correlate with right ventricular function and pulmonary hemodynamics in patients with pulmonary arterial hypertension.
Radiology 2011;258(1):119-27.
2010: Serpil Erzurum; Sharon I Rounds; Troy Stevens; Micheala Aldred; Jason Aliotta; Stephen L Archer; Kewal Asosingh; Robert Balaban; Natalie Bauer; Jahar Bhattacharya; Harm Bogaard; Gaurav Choudhary; Gerald W Dorn; Raed Dweik; Karen Fagan; Michael Fallon; TOREN FINKEL; Mark Geraci; Mark T Gladwin; Paul M Hassoun; Marc Humbert; Naftali Kaminski; Steven M Kawut; Joseph Loscalzo; Donald McDonald; Ivan F McMurtry; John Newman; Mark Nicolls; Marlene Rabinovitch; Judy Shizuru; Masahiko Oka; Peter Polgar; David Rodman; Paul Schumacker; Kurt Stenmark; Rubin M Tuder; Norbert Voelkel; Eugene Sullivan; Richard Weinshilboum; Mervin C Yoder; Yingming Zhao; Dorothy Gail; Timothy M Moore
Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report.
American journal of respiratory and critical care medicine 2010;182(12):1554-62.
2010: Lorinda Chung; Juliana Liu; Lori Parsons; Paul M Hassoun; Michael McGoon; David B Badesch; Dave P Miller; Mark R Nicolls; Roham T Zamanian
Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype.
Chest 2010;138(6):1383-94.
2010: Adel Boueiz; Stephen C Mathai; Laura K Hummers; Paul M Hassoun
Cardiac complications of systemic sclerosis: recent progress in diagnosis.
Current opinion in rheumatology 2010;22(6):696-703.
2010: Brian B Graham; Margaret M Mentink-Kane; Hazim El-Haddad; Shawn Purnell; Li Zhang; Ari L Zaiman; Elizabeth F Redente; David W H Riches; Paul M Hassoun; Angela Bandeira; Hunter C Champion; Ghazwan Butrous; Thomas A Wynn; Rubin M Tuder
Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling.
The American journal of pathology 2010;177(3):1549-61.
2010: Arantza Campo; Stephen C Mathai; Reda E Girgis; Paul M Hassoun
Is pulmonary arterial hypertension really a late complication of systemic sclerosis?
Chest 2010;138(2):461-2; author reply 462-3.
2010: Arantza Campo; Stephen C Mathai; Jérôme Le Pavec; Ari L Zaiman; Laura K Hummers; Danielle Boyce; Traci Housten; Hunter C Champion; Noah Lechtzin; Fredrick M Wigley; Reda E Girgis; Paul M Hassoun
Hemodynamic predictors of survival in scleroderma-related pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2010;182(2):252-60.
2010: Monda L Shehata; Tamer A Basha; Wahid H Tantawy; João A C Lima; Jens Vogel-Claussen; David A Bluemke; Paul M Hassoun; Nael F Osman
Real-time single-heartbeat fast strain-encoded imaging of right ventricular regional function: normal versus chronic pulmonary hypertension.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2010;64(1):98-106.
2010: Jérôme Le Pavec; Marc Humbert; Luc Mouthon; Paul M Hassoun
Systemic sclerosis-associated pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2010;181(12):1285-93.
2010: Xinqi Peng; Mahendra Damarla; Jarrett Skirball; Stephanie A Nonas; Xiao-ying Wang; Eugenia J Han; Emile J Hasan; Xuan Cao; Adel Boueiz; rachel damico; Rubin M Tuder; Alfred M Sciuto; Dana R Anderson; Joe G. N. Garcia; David A Kass; Paul M Hassoun; Jun-tian Zhang
Protective role of PI3-kinase/Akt/eNOS signaling in mechanical stress through inhibition of p38 mitogen-activated protein kinase in mouse lung.
Acta pharmacologica Sinica 2010;31(2):175-83.
2010: Stephen C Mathai; M Bueso; Laura K Hummers; D Boyce; Noah Lechtzin; J Le Pavec; Arantza Campo; Hunter C Champion; T Housten; Paul R Forfia; Ari L Zaiman; Fredrick M Wigley; Reda E Girgis; Paul M Hassoun
Disproportionate elevation of N-terminal pro-brain natriuretic peptide in scleroderma-related pulmonary hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2010;35(1):95-104.
2009: Reda E Girgis; Stephen C Mathai; Fredrick M Wigley; Paul M Hassoun
Survival in systemic sclerosis-related pulmonary arterial hypertension in the modern treatment era.
American journal of respiratory and critical care medicine 2009;180(12):1280; author reply 1280-1.
2009: Narsa Reddy Machireddy; Vegiraju Suryanaraya; Melinda S Yates; Steven R Kleeberger; Paul M Hassoun; Masayuki Yamamoto; Karen T Liby; Michael B Sporn; Thomas W Kensler; SEKHAR POTHIREDDY
The triterpenoid CDDO-imidazolide confers potent protection against hyperoxic acute lung injury in mice.
American journal of respiratory and critical care medicine 2009;180(9):867-74.
2009: Stephen C Mathai; Paul M Hassoun
Therapy for pulmonary arterial hypertension associated with systemic sclerosis.
Current opinion in rheumatology 2009;21(6):642-8.
2009: Daniel Angelini; QINGNING SU; Kazuyo Yamaji-Kegan; Chunling Fan; Xingwu Teng; Paul M Hassoun; Stephen C Yang; Hunter C Champion; Rubin M Tuder; Roger Johns
Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
American journal of respiratory cell and molecular biology 2009;41(5):553-61.
2009: Narsa Reddy Machireddy; Vegiraju Suryanarayana; Dhan V Kalvakolanu; Masayuki Yamamoto; Thomas W Kensler; Paul M Hassoun; Steven R Kleeberger; SEKHAR POTHIREDDY
Innate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4601-8.
2009: Hunter C Champion; Evangelos D Michelakis; Paul M Hassoun
Comprehensive invasive and noninvasive approach to the right ventricle-pulmonary circulation unit: state of the art and clinical and research implications.
Circulation 2009;120(11):992-1007.
2009: Paul M Hassoun
Pulmonary arterial hypertension complicating connective tissue diseases.
Seminars in respiratory and critical care medicine 2009;30(4):429-39.
2009: Marius M Hoeper; Joan Albert Barberà; Richard N Channick; Paul M Hassoun; Irene M Lang; Alessandra Manes; Fernando J Martinez; Robert Naeije; Horst Olschewski; Joanna Pepke-Zaba; Margaret M Redfield; Ivan M Robbins; Rogério Souza; Adam Torbicki; Michael McGoon
Diagnosis, assessment, and treatment of non-pulmonary arterial hypertension pulmonary hypertension.
Journal of the American College of Cardiology 2009;54(1 Suppl):S85-96.
2009: Paul M Hassoun; Luc Mouthon; Joan A Barberà; Saadia Eddahibi; Sonia C Flores; Friedrich Grimminger; Peter Lloyd Jones; Michael L Maitland; Evangelos D Michelakis; Nicholas W Morrell; John H Newman; Marlene Rabinovitch; Ralph Schermuly; Kurt R Stenmark; Norbert F Voelkel; Jason X-J Yuan; Marc Humbert
Inflammation, growth factors, and pulmonary vascular remodeling.
Journal of the American College of Cardiology 2009;54(1 Suppl):S10-9.
2009: Narsa Reddy Machireddy; Steven R Kleeberger; Thomas W Kensler; Masayuki Yamamoto; Paul M Hassoun; SEKHAR POTHIREDDY
Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):7264-71.
2009: James H Finigan; Adel Boueiz; Emily Wilkinson; rachel damico; Jarrett Skirball; Hyun Hae Pae; Mahendra Damarla; Emile Hasan; David B Pearse; SEKHAR POTHIREDDY; Dmitry N Grigoryev; Chris Cheadle; Charles T Esmon; Joe G. N. Garcia; Paul M Hassoun
Activated protein C protects against ventilator-induced pulmonary capillary leak.
American journal of physiology. Lung cellular and molecular physiology 2009;296(6):L1002-11.
2009: Christopher F Barnett; Eric J Bonura; Steven D Nathan; Shahzad Ahmad; Oksana A Shlobin; Kwabena Osei; Ari L Zaiman; Paul M Hassoun; David R Moller; Scott D Barnett; Reda E Girgis
Treatment of sarcoidosis-associated pulmonary hypertension. A two-center experience.
Chest 2009;135(6):1455-61.
2009: Micah R Fisher; Paul R Forfia; Elzbieta Chamera; Traci Housten-Harris; Hunter C Champion; Reda E Girgis; Mary C Corretti; Paul M Hassoun
Accuracy of Doppler echocardiography in the hemodynamic assessment of pulmonary hypertension.
American journal of respiratory and critical care medicine 2009;179(7):615-21.
2009: Stephen C Mathai; Laura K Hummers; Hunter C Champion; Fredrick M Wigley; Ari L Zaiman; Paul M Hassoun; Reda E Girgis
Survival in pulmonary hypertension associated with the scleroderma spectrum of diseases: impact of interstitial lung disease.
Arthritis and rheumatism 2009;60(2):569-77.
2009: Mahendra Damarla; Emile Hasan; Adel Boueiz; Anne Le; Hyun Hae Pae; Calypso Montouchet; Todd Matthew Kolb; Tiffany Simms; Allen C Myers; Usamah S Kayyali; Matthias Gaestel; Xinqi Peng; SEKHAR POTHIREDDY; rachel damico; Paul M Hassoun
Mitogen activated protein kinase activated protein kinase 2 regulates actin polymerization and vascular leak in ventilator associated lung injury.
PloS one 2009;4(2):e4600.
2009: Adel Boueiz; Paul M Hassoun
Regulation of endothelial barrier function by reactive oxygen and nitrogen species.
Microvascular research 2009;77(1):26-34.
2009: Jeffrey M Dodd-o; Maria Hristopoulos; Daniel O Scharfstein; Roy G Brower; Paul M Hassoun; Landon S King; Patrice M Becker; Manchang Liu; Weiwei Wang; Heitham T Hassoun; Hamid Rabb
Interactive effects of mechanical ventilation and kidney health on lung function in an in vivo mouse model.
American journal of physiology. Lung cellular and molecular physiology 2009;296(1):L3-L11.
2008: Alexis Bierman; Adi N Yerrapureddy; Narsa Reddy Machireddy; Paul M Hassoun; SEKHAR POTHIREDDY
Epidermal growth factor receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice.
Translational research : the journal of laboratory and clinical medicine 2008;152(6):265-72.
2008: Eric P Schmidt; Mahendra Damarla; Otgonchimeg Rentsendorj; Laura E Servinsky; Bing Zhu; Aigul Moldobaeva; Alfredo Gonzalez; Paul M Hassoun; David B Pearse
Soluble guanylyl cyclase contributes to ventilator-induced lung injury in mice.
American journal of physiology. Lung cellular and molecular physiology 2008;295(6):L1056-65.
2008: Ryan J Tedford; Anna R Hemnes; Stuart D Russell; Ilan S Wittstein; Mobusher Mahmud; Ari L Zaiman; Stephen C Mathai; David R Thiemann; Paul M Hassoun; Reda E Girgis; Jonathan B Orens; Ashish S Shah; David D Yuh; John V Conte; Hunter C Champion
PDE5A inhibitor treatment of persistent pulmonary hypertension after mechanical circulatory support.
Circulation. Heart failure 2008;1(4):213-9.
2008: Anne Le; rachel damico; Mahendra Damarla; Adel Boueiz; Hyun Hae Pae; Jarrett Skirball; Emile Hasan; Xinqi Peng; Alan Chesley; Michael T Crow; SEKHAR POTHIREDDY; Rubin M Tuder; Paul M Hassoun
Alveolar cell apoptosis is dependent on p38 MAP kinase-mediated activation of xanthine oxidoreductase in ventilator-induced lung injury.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;105(4):1282-90.
2008: Paul R Forfia; Stephen C Mathai; Micah R Fisher; Traci Housten-Harris; Anna R Hemnes; Hunter C Champion; Reda E Girgis; Paul M Hassoun
Hyponatremia predicts right heart failure and poor survival in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2008;177(12):1364-9.
2008: Adel Boueiz; Mahendra Damarla; Paul M Hassoun
Xanthine oxidoreductase in respiratory and cardiovascular disorders.
American journal of physiology. Lung cellular and molecular physiology 2008;294(5):L830-40.
2008: Dmitry N Grigoryev; Stephen C Mathai; Micah R Fisher; Reda E Girgis; Ari L Zaiman; Traci Housten-Harris; Chris Cheadle; Li Gao; Laura K Hummers; Hunter C Champion; Joe G. N. Garcia; Fredrick M Wigley; Rubin M Tuder; Kathleen C Barnes; Paul M Hassoun
Identification of candidate genes in scleroderma-related pulmonary arterial hypertension.
Translational research : the journal of laboratory and clinical medicine 2008;151(4):197-207.
2007: Srinivas Papaiahgari; Adi Yerrapureddy; Swetha R Reddy; Narsa Reddy Machireddy; Jeffrey M Dodd-o; Michael T Crow; Dmitry N Grigoryev; Kathleen C Barnes; Rubin M Tuder; Masayuki Yamamoto; Thomas W Kensler; Shyam Biswal; Wayne Mitzner; Paul M Hassoun; SEKHAR POTHIREDDY
Genetic and pharmacologic evidence links oxidative stress to ventilator-induced lung injury in mice.
American journal of respiratory and critical care medicine 2007;176(12):1222-35.
2007: SEKHAR POTHIREDDY; Paul M Hassoun; Roy G Brower
Redox imbalance and ventilator-induced lung injury.
Antioxidants & redox signaling 2007;9(11):2003-12.
2007: Micah R Fisher; Gerard J Criner; Alfred P Fishman; Paul M Hassoun; Omar A Minai; Steven M Scharf; Henry E Fessler
Estimating pulmonary artery pressures by echocardiography in patients with emphysema.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;30(5):914-21.
2007: Stephanie A Nonas; Liliana Moreno Vinasco; Liliana Moreno Vinasco; Shwu-Fan Ma; Jeffrey Jacobson; Ankit A Desai; Steven M Dudek; Carlos Flores; Paul M Hassoun; Lee Sam; Shui Q Ye; Jaideep Moitra; Joe Barnard; Dmitry N Grigoryev; Yves lussier; Joe G. N. Garcia
Use of consomic rats for genomic insights into ventilator-associated lung injury.
American journal of physiology. Lung cellular and molecular physiology 2007;293(2):L292-302.
2007: Reda E Girgis; Shehzin Mozammel; Hunter C Champion; Dechun Li; Xinqi Peng; Larissa A Shimoda; Rubin M Tuder; Roger Johns; Paul M Hassoun
Regression of chronic hypoxic pulmonary hypertension by simvastatin.
American journal of physiology. Lung cellular and molecular physiology 2007;292(5):L1105-10.
2007: Stephen C Mathai; Reda E Girgis; Micah R Fisher; Hunter C Champion; Traci Housten-Harris; Ari L Zaiman; Paul M Hassoun
Addition of sildenafil to bosentan monotherapy in pulmonary arterial hypertension.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(3):469-75.
2007: Srinivas Papaiahgari; Adi N Yerrapureddy; Paul M Hassoun; Joe G. N. Garcia; Konstantin G Birukov; SEKHAR POTHIREDDY
EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation.
American journal of respiratory cell and molecular biology 2007;36(3):304-12.
2007: Stephen C Mathai; Paul M Hassoun
N-terminal brain natriuretic peptide in scleroderma-associated pulmonary arterial hypertension.
European heart journal 2007;28(1):140-1; author reply 141.
2006: Paul R Forfia; Micah R Fisher; Stephen C Mathai; Traci Housten-Harris; Anna R Hemnes; Barry A Borlaug; Elzbieta Chamera; Mary C Corretti; Hunter C Champion; Theodore P Abraham; Reda E Girgis; Paul M Hassoun
Tricuspid annular displacement predicts survival in pulmonary hypertension.
American journal of respiratory and critical care medicine 2006;174(9):1034-41.
2006: Micah R Fisher; Stephen C Mathai; Hunter C Champion; Reda E Girgis; Traci Housten-Harris; Laura K Hummers; Jerry Krishnan; Fredrick M Wigley; Paul M Hassoun
Clinical differences between idiopathic and scleroderma-related pulmonary hypertension.
Arthritis and rheumatism 2006;54(9):3043-50.
2006: Raja-Elie E Abdulnour; Xinqi Peng; Jay H Finigan; Eugenia J Han; Emile J Hasan; Konstantin G Birukov; SEKHAR POTHIREDDY; James E Watkins; Usamah S Kayyali; Joe G. N. Garcia; Rubin M Tuder; Paul M Hassoun
Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways.
American journal of physiology. Lung cellular and molecular physiology 2006;291(3):L345-53.
2005: Reda E Girgis; Shwu-Fan Ma; S Ye; Dmitry N Grigoryev; Dechun Li; Paul M Hassoun; Rubin M Tuder; Roger Johns; Joe G. N. Garcia
Differential gene expression in chronic hypoxic pulmonary hypertension: effect of simvastatin treatment.
Chest 2005;128(6 Suppl):579S.
2005: Ari L Zaiman; IWONA FIJALKOWSKA-GORZKA; Paul M Hassoun; Rubin M Tuder
One hundred years of research in the pathogenesis of pulmonary hypertension.
American journal of respiratory cell and molecular biology 2005;33(5):425-31.
2005: Reda E Girgis; Stephen C Mathai; Jerry Krishnan; Fredrick M Wigley; Paul M Hassoun
Long-term outcome of bosentan treatment in idiopathic pulmonary arterial hypertension and pulmonary arterial hypertension associated with the scleroderma spectrum of diseases.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2005;24(10):1626-31.
2005: Steven S An; Corin M Pennella; Achuta Gonnabathula; Jianxin Chen; Ning Wang; Matthias Gaestel; Paul M Hassoun; Jeffrey J Fredberg; Usamah S Kayyali
Hypoxia alters biophysical properties of endothelial cells via p38 MAPK- and Rho kinase-dependent pathways.
American journal of physiology. Cell physiology 2005;289(3):C521-30.
2005: Xinqi Peng; Raja-Elie E Abdulnour; Saad Sammani; Shwu-Fan Ma; Eugenia J Han; Emile J Hasan; Rubin M Tuder; Joe G. N. Garcia; Paul M Hassoun
Inducible nitric oxide synthase contributes to ventilator-induced lung injury.
American journal of respiratory and critical care medicine 2005;172(4):470-9.
2005: Micah R Fisher; Paul M Hassoun
Prediction of pulmonary artery pressure.
Chest 2005;128(1):466-7; author reply 467.
2005: Paul M Hassoun
Deciphering the "matrix" in pulmonary vascular remodelling.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;25(5):778-9.
2004: Dmitry N Grigoryev; James H Finigan; Paul M Hassoun; Joe G. N. Garcia
Science review: searching for gene candidates in acute lung injury.
Critical care (London, England) 2004;8(6):440-7.
2004: Maged A Tanios; Hesham El Gamal; Beth J Rosenberg; Paul M Hassoun
Can we still miss tetrachloroethylene-induced lung disease? The emperor returns in new clothes.
Respiration; international review of thoracic diseases 2004;71(6):642-5.
2004: Bryan J McVerry; Xinqi Peng; Paul M Hassoun; Saad Sammani; Bret Simon; Joe G. N. Garcia
Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury.
American journal of respiratory and critical care medicine 2004;170(9):987-93.
2004: Paul M Hassoun; Jerry Krishnan
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease.
The New England journal of medicine 2004;350(24):2521-2; author reply 2521-2.
2004: Xinqi Peng; Paul M Hassoun; Saad Sammani; Bryan J McVerry; Melissa J Burne; Hamid Rabb; David B Pearse; Rubin M Tuder; Joe G. N. Garcia
Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury.
American journal of respiratory and critical care medicine 2004;169(11):1245-51.
2004: Paul M Hassoun; Galina Filippov; Michael Fogel; Cam Donaldson; Usamah S Kayyali; Larissa A Shimoda; Kenneth D Bloch
Hypoxia decreases expression of soluble guanylate cyclase in cultured rat pulmonary artery smooth muscle cells.
American journal of respiratory cell and molecular biology 2004;30(6):908-13.
2004: Mariano Severgnini; Satoe Takahashi; Liliana M Rozo; Robert J Homer; Charles Kuhn; Jhung W Jhung; George Perides; Michael L Steer; Paul M Hassoun; Barry L Fanburg; Brent H Cochran; Amy R Simon
Activation of the STAT pathway in acute lung injury.
American journal of physiology. Lung cellular and molecular physiology 2004;286(6):L1282-92.
2004: Maged A Tanios; Hesham El Gamal; Scott K Epstein; Paul M Hassoun
Severe respiratory muscle weakness related to long-term colchicine therapy.
Respiratory care 2004;49(2):189-91.
2004: Rohit Budhiraja; Rubin M Tuder; Paul M Hassoun
Endothelial dysfunction in pulmonary hypertension.
Circulation 2004;109(2):159-65.
2003: Rohit Budhiraja; Usamah S Kayyali; Mallik Karamsetty; Michael Fogel; Nicholas S Hill; Roger Chalkley; Geraldine A Finlay; Paul M Hassoun
Estrogen modulates xanthine dehydrogenase/xanthine oxidase activity by a receptor-independent mechanism.
Antioxidants & redox signaling 2003;5(6):705-11.
2003: Reda E Girgis; Dechun Li; Xinhua Zhan; Joe G. N. Garcia; Rubin M Tuder; Paul M Hassoun; Roger Johns
Attenuation of chronic hypoxic pulmonary hypertension by simvastatin.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H938-45.
2003: Usamah S Kayyali; Rohit Budhiraja; Corin M Pennella; Samantha Cooray; Joseph J Lanzillo; Roger Chalkley; Paul M Hassoun
Upregulation of xanthine oxidase by tobacco smoke condensate in pulmonary endothelial cells.
Toxicology and applied pharmacology 2003;188(1):59-68.
2003: Rohit Budhiraja; Paul M Hassoun
Portopulmonary hypertension: a tale of two circulations.
Chest 2003;123(2):562-76.
2002: Usamah S Kayyali; Corin M Pennella; Carolina Trujillo; Otto Villa; Matthias Gaestel; Paul M Hassoun
Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2.
The Journal of biological chemistry 2002;277(45):42596-602.
2002: Matthew J Curley; Shakir A Hussein; Paul M Hassoun
Disseminated herpes simplex virus and varicella zoster virus coinfection in a patient taking thalidomide for relapsed multiple myeloma.
Journal of clinical microbiology 2002;40(6):2302-4.
2002: Javier J Zulueta; Raneeta Sawhney; Usamah S Kayyali; Michael Fogel; Cam Donaldson; Hailu Huang; Joseph J Lanzillo; Paul M Hassoun
Modulation of inducible nitric oxide synthase by hypoxia in pulmonary artery endothelial cells.
American journal of respiratory cell and molecular biology 2002;26(1):22-30.
2001: Usamah S Kayyali; Cam Donaldson; H Huang; R Abdelnour; Paul M Hassoun
Phosphorylation of xanthine dehydrogenase/oxidase in hypoxia.
The Journal of biological chemistry 2001;276(17):14359-65.
2001: Maged A Tanios; L Kogelman; B McGovern; Paul M Hassoun
Acute respiratory distress syndrome complicating Plasmodium vivax malaria.
Critical care medicine 2001;29(3):665-7.
2001: Maged A Tanios; Amy R Simon; Paul M Hassoun
Management of venous thromboembolic disease in the chronically critically ill patient.
Clinics in chest medicine 2001;22(1):105-22.
2000: Marilyn P Merker; Bruce R Pitt; A M Choi; Paul M Hassoun; Christopher A Dawson; A B Fisher
Lung redox homeostasis: emerging concepts.
American journal of physiology. Lung cellular and molecular physiology 2000;279(3):L413-7.
2000: Paul M Hassoun; B R Celli
Bilateral diaphragm paralysis secondary to central von Recklinghausen's disease.
Chest 2000;117(4):1196-200.
1999: E D Libby; R Fawaz; A M Leano; Paul M Hassoun
Airway complication of expandable stents.
Gastrointestinal endoscopy 1999;49(1):136-7.
1998: C G Cote; R Cicchelli; Paul M Hassoun
Hemoptysis and a lung mass in a 51-year-old patient with asthma.
Chest 1998;114(5):1465-8.
1998: Paul M Hassoun; F S Yu; C G Cote; Javier J Zulueta; R Sawhney; Kelly A Skinner; Henry Skinner; Dale A Parks; Joseph J Lanzillo
Upregulation of xanthine oxidase by lipopolysaccharide, interleukin-1, and hypoxia. Role in acute lung injury.
American journal of respiratory and critical care medicine 1998;158(1):299-305.
1998: R J Vosatka; Paul M Hassoun; K B Harvey-Wilkes
Dietary L-arginine prevents fetal growth restriction in rats.
American journal of obstetrics and gynecology 1998;178(2):242-6.
1997: Javier J Zulueta; R Sawhney; F S Yu; C C Cote; Paul M Hassoun
Intracellular generation of reactive oxygen species in endothelial cells exposed to anoxia-reoxygenation.
The American journal of physiology 1997;272(5 Pt 1):L897-902.
1996: J J Lanzillo; F S Yu; J Stevens; Paul M Hassoun
Determination of xanthine dehydrogenase mRNA by a reverse transcription-coupled competitive quantitative polymerase chain reaction assay: regulation in rat endothelial cells by hypoxia and hyperoxia.
Archives of biochemistry and biophysics 1996;335(2):377-80.
1996: C G Cote; F S Yu; Javier J Zulueta; R J Vosatka; Paul M Hassoun
Regulation of intracellular xanthine oxidase by endothelial-derived nitric oxide.
The American journal of physiology 1996;271(5 Pt 1):L869-74.
1996: Ayman O Soubani; K B Miller; Paul M Hassoun
Pulmonary complications of bone marrow transplantation.
Chest 1996;109(4):1066-77.
1996: J Stevens; F S Yu; Paul M Hassoun; J J Lanzillo
Quantification of polymerase chain reaction products: enzyme immunoassay based systems for digoxigenin- and biotin-labelled products that quantify either total or specific amplicons.
Molecular and cellular probes 1996;10(1):31-41.
1996: A Martin; J Zulueta; Paul M Hassoun; J B Blumberg; M Meydani
Effect of vitamin E on hydrogen peroxide production by human vascular endothelial cells after hypoxia/reoxygenation.
Free radical biology & medicine 1996;20(1):99-105.
1995: James K Liao; Javier J Zulueta; F S Yu; H B Peng; C G Cote; Paul M Hassoun
Regulation of bovine endothelial constitutive nitric oxide synthase by oxygen.
The Journal of clinical investigation 1995;96(6):2661-6.
1995: A C White; E K Maloney; M R Boustani; Paul M Hassoun; Barry L Fanburg
Nitric oxide increases cellular glutathione levels in rat lung fibroblasts.
American journal of respiratory cell and molecular biology 1995;13(4):442-8.
1995: Paul M Hassoun; F S Yu; Javier J Zulueta; A C White; J J Lanzillo
Effect of nitric oxide and cell redox status on the regulation of endothelial cell xanthine dehydrogenase.
The American journal of physiology 1995;268(5 Pt 1):L809-17.
1995: Javier J Zulueta; F S Yu; I A Hertig; Victor J Thannickal; Paul M Hassoun
Release of hydrogen peroxide in response to hypoxia-reoxygenation: role of an NAD(P)H oxidase-like enzyme in endothelial cell plasma membrane.
American journal of respiratory cell and molecular biology 1995;12(1):41-9.
1994: Paul M Hassoun; F S Yu; A L Shedd; Javier J Zulueta; Victor J Thannickal; J J Lanzillo; Barry L Fanburg
Regulation of endothelial cell xanthine dehydrogenase xanthine oxidase gene expression by oxygen tension.
The American journal of physiology 1994;266(2 Pt 1):L163-71.
1993: Victor J Thannickal; Paul M Hassoun; A C White; Barry L Fanburg
Enhanced rate of H2O2 release from bovine pulmonary artery endothelial cells induced by TGF-beta 1.
The American journal of physiology 1993;265(6 Pt 1):L622-6.
1993: I A Hertig; Paul M Hassoun; Javier J Zulueta; Victor J Thannickal; Barry L Fanburg
Mechanism of basal and transforming growth factor beta 1 stimulated H2O2 release by endothelial cells.
Transactions of the Association of American Physicians 1993;106():179-86.
1992: Paul M Hassoun; A L Shedd; J J Lanzillo; V Thappa; M J Landman; Barry L Fanburg
Inhibition of pulmonary artery smooth muscle cell growth by hypoxanthine, xanthine, and uric acid.
American journal of respiratory cell and molecular biology 1992;6(6):617-24.
1992: Paul M Hassoun; V Thappa; M J Landman; Barry L Fanburg
Endothelin 1: mitogenic activity on pulmonary artery smooth muscle cells and release from hypoxic endothelial cells.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1992;199(2):165-70.
1992: Paul M Hassoun; B Taylor Thompson; Charles A Hales
Partial reversal of hypoxic pulmonary hypertension by heparin.
The American review of respiratory disease 1992;145(1):193-6.
1992: P J Pasricha; Paul M Hassoun; E Teufel; M J Landman; Barry L Fanburg
Prostaglandins E1 and E2 stimulate the proliferation of pulmonary artery smooth muscle cells.
Prostaglandins 1992;43(1):5-19.
1989: Paul M Hassoun; P J Pasricha; E Teufel; SL Lee; Barry L Fanburg
Hypoxia stimulates the release by bovine pulmonary artery endothelial cells of an inhibitor of pulmonary artery smooth muscle cell growth.
American journal of respiratory cell and molecular biology 1989;1(5):377-84.
1989: Paul M Hassoun; B Taylor Thompson; D Steigman; Charles A Hales
Effect of heparin and warfarin on chronic hypoxic pulmonary hypertension and vascular remodeling in the guinea pig.
The American review of respiratory disease 1989;139(3):763-8.
1989: B Taylor Thompson; Paul M Hassoun; Richard L Kradin; Charles A Hales
Acute and chronic hypoxic pulmonary hypertension in guinea pigs.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;66(2):920-8.
1988: Paul M Hassoun; K E Shepherd; T J Flotte; H Kazemi
Erythema induratum and active pulmonary tuberculosis.
The American journal of medicine 1988;84(4):784-5.