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Hiroshi Hatanaka

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Yumiko Numakawa; Tomoya Matsumoto; Daisaku Yokomaku; Takahisa Taguchi; Etsuo Niki; Hiroshi Hatanaka; Hiroshi Kunugi; Tadahiro Numakawa
17beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium.
Keiji Nishiyama; Akio Konishi; Chika Nishio; Kiyomi Araki-Yoshida; Hiroshi Hatanaka; Masami Kojima; Yoshihiro Ohmiya; Masashi Yamada; Hisatsugu Koshimizu
Expression of cystatin C prevents oxidative stress-induced death in PC12 cells.
Satoru Yamagishi; Tomoya Matsumoto; Tadahiro Numakawa; Daisaku Yokomaku; Naoki Adachi; Hiroshi Hatanaka; Masashi Yamada; Koji Shimoke; Toshihiko Ikeuchi
ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.

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All Publications

2007: Yumiko Numakawa; Tomoya Matsumoto; Daisaku Yokomaku; Takahisa Taguchi; Etsuo Niki; Hiroshi Hatanaka; Hiroshi Kunugi; Tadahiro Numakawa
17beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium.
Endocrinology 2007;148(2):627-37.
2005: Keiji Nishiyama; Akio Konishi; Chika Nishio; Kiyomi Araki-Yoshida; Hiroshi Hatanaka; Masami Kojima; Yoshihiro Ohmiya; Masashi Yamada; Hisatsugu Koshimizu
Expression of cystatin C prevents oxidative stress-induced death in PC12 cells.
Brain research bulletin 2005;67(1-2):94-9.
2005: Satoru Yamagishi; Tomoya Matsumoto; Tadahiro Numakawa; Daisaku Yokomaku; Naoki Adachi; Hiroshi Hatanaka; Masashi Yamada; Koji Shimoke; Toshihiko Ikeuchi
ERK1/2 are involved in low potassium-induced apoptotic signaling downstream of ASK1-p38 MAPK pathway in cultured cerebellar granule neurons.
Brain research 2005;1038(2):223-30.
2004: Shingo Suzuki; Tadahiro Numakawa; Kazuhiro Shimazu; Hisatsugu Koshimizu; Tomoko Hara; Hiroshi Hatanaka; Lin Mei; Bai Lu; Masami Kojima
BDNF-induced recruitment of TrkB receptor into neuronal lipid rafts: roles in synaptic modulation.
The Journal of cell biology 2004;167(6):1205-15.
2003: Satoru Yamagishi; Tomoya Matsumoto; Daisaku Yokomaku; Hiroshi Hatanaka; Koji Shimoke; Masashi Yamada; Toshihiko Ikeuchi
Comparison of inhibitory effects of brain-derived neurotrophic factor and insulin-like growth factor on low potassium-induced apoptosis and activation of p38 MAPK and c-Jun in cultured cerebellar granule neurons.
Brain research. Molecular brain research 2003;119(2):184-91.
2003: Yasuyuki Ishikawa; Eiko Kusaka; Yasushi Enokido; Toshihiko Ikeuchi; Hiroshi Hatanaka
Regulation of Bax translocation through phosphorylation at Ser-70 of Bcl-2 by MAP kinase in NO-induced neuronal apoptosis.
Molecular and cellular neurosciences 2003;24(2):451-9.
2003: Satoru Yamagishi; Masashi Yamada; Hisatsugu Koshimizu; Satomi Takai; Hiroshi Hatanaka; Kohsuke Takeda; Hidenori Ichijo; Koji Shimoke; Toshihiko Ikeuchi
Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons.
Journal of biochemistry 2003;133(6):719-24.
2003: Daisaku Yokomaku; Tadahiro Numakawa; Yumiko Numakawa; Shingo Suzuki; Tomoya Matsumoto; Naoki Adachi; Chika Nishio; Takahisa Taguchi; Hiroshi Hatanaka
Estrogen enhances depolarization-induced glutamate release through activation of phosphatidylinositol 3-kinase and mitogen-activated protein kinase in cultured hippocampal neurons.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):831-44.
2003: Aki Yuhara; Kyoko Ishii; Chika Nishio; Yasuhiro Abiru; Masashi Yamada; Hiroyuki Nawa; Hiroshi Hatanaka; Nobuyuki Takei
PACAP and NGF cooperatively enhance choline acetyltransferase activity in postnatal basal forebrain neurons by complementary induction of its different mRNA species.
Biochemical and biophysical research communications 2003;301(2):344-9.
2002: Masashi Yamada; Tadahiro Numakawa; Hisatsugu Koshimizu; Keiko Tanabe; Kazuyo Wada; Shinichi Koizumi; Hiroshi Hatanaka
Distinct usages of phospholipase C gamma and Shc in intracellular signaling stimulated by neurotrophins.
Brain research 2002;955(1-2):183-90.
2002: Tadahiro Numakawa; Daisaku Yokomaku; Kazuyuki Kiyosue; Naoki Adachi; Tomoya Matsumoto; Yumiko Numakawa; Takahisa Taguchi; Hiroshi Hatanaka; Masashi Yamada
Basic fibroblast growth factor evokes a rapid glutamate release through activation of the MAPK pathway in cultured cortical neurons.
The Journal of biological chemistry 2002;277(32):28861-9.
2002: Satomi Takai; Masashi Yamada; Toshiyuki Araki; Hisatsugu Koshimizu; Hiroyuki Nawa; Hiroshi Hatanaka
Shp-2 positively regulates brain-derived neurotrophic factor-promoted survival of cultured ventral mesencephalic dopaminergic neurons through a brain immunoglobulin-like molecule with tyrosine-based activation motifs/Shp substrate-1.
Journal of neurochemistry 2002;82(2):353-64.
2002: Hisatsugu Koshimizu; Toshiyuki Araki; Satomi Takai; Daisaku Yokomaku; Yasuyuki Ishikawa; Misae Kubota; Shin-ichiro Sano; Hiroshi Hatanaka; Masashi Yamada
Expression of CD47/integrin-associated protein induces death of cultured cerebral cortical neurons.
Journal of neurochemistry 2002;82(2):249-57.
2002: Shingo Suzuki; Masaharu Mizutani; Kenji Suzuki; Masashi Yamada; Masami Kojima; Hiroshi Hatanaka; Shinichi Koizumi
Brain-derived neurotrophic factor promotes interaction of the Nck2 adaptor protein with the TrkB tyrosine kinase receptor.
Biochemical and biophysical research communications 2002;294(5):1087-92.
2002: Yasushi Enokido; Hisato Maruoka; Hiroshi Hatanaka; I Kanazawa; hitoshi okazawa
PQBP-1 increases vulnerability to low potassium stress and represses transcription in primary cerebellar neurons.
Biochemical and biophysical research communications 2002;294(2):268-71.
2002: hitoshi okazawa; Tina Rich; Alex Chang; Xi Lin; Masaaki Waragai; Masunori Kajikawa; Yasushi Enokido; Akihiko Komuro; Seishi Kato; Masao Shibata; Hiroshi Hatanaka; M Maral Mouradian; Marius Sudol; Ichiro Kanazawa
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
Neuron 2002;34(5):701-13.
2002: Tadahiro Numakawa; Satoru Yamagishi; Naoki Adachi; Tomoya Matsumoto; Daisaku Yokomaku; Masashi Yamada; Hiroshi Hatanaka
Brain-derived neurotrophic factor-induced potentiation of Ca(2+) oscillations in developing cortical neurons.
The Journal of biological chemistry 2002;277(8):6520-9.
2001: Aki Yuhara; Chika Nishio; Yasuhiro Abiru; Hiroshi Hatanaka; Nobuyuki Takei
PACAP has a neurotrophic effect on cultured basal forebrain cholinergic neurons from adult rats.
Brain research. Developmental brain research 2001;131(1-2):41-5.
2001: M Murai; Yasushi Enokido; N Inamura; Masafumi Yoshino; Yoshimichi Nakatsu; G T van der Horst; Jan H J Hoeijmakers; Keiichi Tanaka; Hiroshi Hatanaka
Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13379-84.
2001: Tomoya Matsumoto; Tadahiro Numakawa; Naoki Adachi; Daisaku Yokomaku; Satoru Yamagishi; Nobuyuki Takei; Hiroshi Hatanaka
Brain-derived neurotrophic factor enhances depolarization-evoked glutamate release in cultured cortical neurons.
Journal of neurochemistry 2001;79(3):522-30.
2001: Tadahiro Numakawa; Tomoya Matsumoto; Naoki Adachi; Daisaku Yokomaku; M Kojima; Nobuyuki Takei; Hiroshi Hatanaka
Brain-derived neurotrophic factor triggers a rapid glutamate release through increase of intracellular Ca(2+) and Na(+) in cultured cerebellar neurons.
Journal of neuroscience research 2001;66(1):96-108.
2001: Masashi Yamada; K Tanabe; Koichiro Wada; Koji Shimoke; Yasuyuki Ishikawa; Toshihiko Ikeuchi; Shinichi Koizumi; Hiroshi Hatanaka
Differences in survival-promoting effects and intracellular signaling properties of BDNF and IGF-1 in cultured cerebral cortical neurons.
Journal of neurochemistry 2001;78(5):940-51.
2001: Masashi Yamada; Keiichiro Suzuki; M Mizutani; A Asada; Takashi Matozaki; Toshihiko Ikeuchi; Shinichi Koizumi; Hiroshi Hatanaka
Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system.
Journal of biochemistry 2001;130(1):157-65.
2001: N Inamura; Yasushi Enokido; Hiroshi Hatanaka
Involvement of c-Jun N-terminal kinase and caspase 3-like protease in DNA damage-induced, p53-mediated apoptosis of cultured mouse cerebellar granule neurons.
Brain research 2001;904(2):270-8.
2001: Satoru Yamagishi; Masashi Yamada; Y Ishikawa; Tomoya Matsumoto; Toshihiko Ikeuchi; Hiroshi Hatanaka
p38 mitogen-activated protein kinase regulates low potassium-induced c-Jun phosphorylation and apoptosis in cultured cerebellar granule neurons.
The Journal of biological chemistry 2001;276(7):5129-33.
2000: Toshiyuki Araki; Masashi Yamada; Hiroshi Ohnishi; S i Sano; Hiroshi Hatanaka
BIT/SHPS-1 enhances brain-derived neurotrophic factor-promoted neuronal survival in cultured cerebral cortical neurons.
Journal of neurochemistry 2000;75(4):1502-10.
2000: Kyoko Yoshida; Masashi Yamada; Chika Nishio; Akio Konishi; Hiroshi Hatanaka
SNRK, a member of the SNF1 family, is related to low K(+)-induced apoptosis of cultured rat cerebellar granule neurons.
Brain research 2000;873(2):274-82.
2000: Chika Nishio; Kyoko Yoshida; K Nishiyama; Hiroshi Hatanaka; Masashi Yamada
Involvement of cystatin C in oxidative stress-induced apoptosis of cultured rat CNS neurons.
Brain research 2000;873(2):252-62.
2000: Yasuyuki Ishikawa; Toshihiko Ikeuchi; Hiroshi Hatanaka
Brain-derived neurotrophic factor accelerates nitric oxide donor-induced apoptosis of cultured cortical neurons.
Journal of neurochemistry 2000;75(2):494-502.
2000: Nobuyuki Takei; E Torres; Aki Yuhara; H Jongsma; C Otto; Laura Korhonen; Yasuhiro Abiru; Y Skoglösa; G Schütz; Hiroshi Hatanaka; M V Sofroniew; Dan Lindholm
Pituitary adenylate cyclase-activating polypeptide promotes the survival of basal forebrain cholinergic neurons in vitro and in vivo: comparison with effects of nerve growth factor.
The European journal of neuroscience 2000;12(7):2273-80.
2000: N Inamura; Toshiyuki Araki; Yasushi Enokido; Chika Nishio; S Aizawa; Hiroshi Hatanaka
Role of p53 in DNA strand break-induced apoptosis in organotypic slice culture from the mouse cerebellum.
Journal of neuroscience research 2000;60(4):450-7.
2000: Tadahiro Numakawa; Nobuyuki Takei; Hiroshi Hatanaka
BDNF rapidly induces aspartate release from cultured CNS neurons.
Neuroscience research 2000;37(1):59-65.
2000: Toshiyuki Araki; Masashi Yamada; Hiroshi Ohnishi; S i Sano; Taichi Uetsuki; Hiroshi Hatanaka
Shp-2 specifically regulates several tyrosine-phosphorylated proteins in brain-derived neurotrophic factor signaling in cultured cerebral cortical neurons.
Journal of neurochemistry 2000;74(2):659-68.
1999: T Yamagata; T Satoh; Yasuyuki Ishikawa; Atsutoshi Nakatani; Masashi Yamada; Toshihiko Ikeuchi; Hiroshi Hatanaka
Brain-derived neurotropic factor prevents superoxide anion-induced death of PC12h cells stably expressing TrkB receptor via modulation of reactive oxygen species.
Neuroscience research 1999;35(1):9-17.
1999: Tadahiro Numakawa; Nobuyuki Takei; Satoru Yamagishi; N Sakai; Hiroshi Hatanaka
Neurotrophin-elicited short-term glutamate release from cultured cerebellar granule neurons.
Brain research 1999;842(2):431-8.
1999: Masashi Yamada; Hiroshi Ohnishi; S i Sano; Toshiyuki Araki; Atsutoshi Nakatani; Toshihiko Ikeuchi; Hiroshi Hatanaka
Brain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neurons.
Journal of neurochemistry 1999;73(1):41-9.
1999: Y Hashimoto; Yasuhiro Abiru; Chika Nishio; Hiroshi Hatanaka
Synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor on cultured basal forebrain cholinergic neurons from postnatal 2-week-old rats.
Brain research. Developmental brain research 1999;115(1):25-32.
1999: T Satoh; T Yamagata; Y Ishikawa; Masashi Yamada; Y Uchiyama; Hiroshi Hatanaka
Regulation of reactive oxygen species by nerve growth factor but not Bcl-2 as a novel mechanism of protection of PC12 cells from superoxide anion-induced death.
Journal of biochemistry 1999;125(5):952-9.
1999: Y Ishikawa; T Satoh; Yasushi Enokido; Chika Nishio; Toshihiko Ikeuchi; Hiroshi Hatanaka
Generation of reactive oxygen species, release of L-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture.
Brain research 1999;824(1):71-80.
1999: S Kinoshita; Hiroki Yasuda; N Taniguchi; Ritsuko Katoh-Semba; Hiroshi Hatanaka; Tadaharu Tsumoto
Brain-derived neurotrophic factor prevents low-frequency inputs from inducing long-term depression in the developing visual cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(6):2122-30.
1999: Koji Shimoke; Satoru Yamagishi; Masashi Yamada; Toshihiko Ikeuchi; Hiroshi Hatanaka
Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons.
Brain research. Developmental brain research 1999;112(2):245-53.
1998: T Satoh; Yasushi Enokido; T Kubo; M Yamada; Hiroshi Hatanaka
Oxygen toxicity induces apoptosis in neuronal cells.
Cellular and molecular neurobiology 1998;18(6):649-66.
1998: Yasuhiro Abiru; Ritsuko Katoh-Semba; Chika Nishio; Hiroshi Hatanaka
High potassium enhances secretion of neurotrophic factors from cultured astrocytes.
Brain research 1998;809(1):115-26.
1998: Koji Shimoke; Mitsuhiko Yamada; Toshihiko Ikeuchi; Hiroshi Hatanaka
Synthetic lipid products of PI3-kinase which are added to culture medium prevent low K+-induced apoptosis of cerebellar granule neurons via Akt kinase activation.
FEBS letters 1998;437(3):221-4.
1998: Toshihiko Ikeuchi; Koji Shimoke; T Kubo; M Yamada; Hiroshi Hatanaka
[Apoptosis-inducing and -preventing signal transduction pathways in cultured cerebellar granule neurons].
Human cell 1998;11(3):125-40.
1998: Toshiyuki Araki; Yasushi Enokido; N Inamura; S Aizawa; J C Reed; Hiroshi Hatanaka
Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin.
Brain research 1998;794(2):239-47.
1998: Atsutoshi Nakatani; Masashi Yamada; A Asada; Masato Okada; Toshihiko Ikeuchi; Hiroshi Hatanaka
Comparison of survival-promoting effects of brain-derived neurotrophic factor and neurotrophin-3 on PC12h cells stably expressing TrkB receptor.
Journal of biochemistry 1998;123(4):707-14.
1998: Toshihiko Ikeuchi; Atsutoshi Nakatani; Masashi Yamada; N Itokazu; Akira Awaya; Hiroshi Hatanaka
MS-430, a synthetic pyrimidine derivative, influences the intracellular signal transduction pathway leading to neuronal differentiation of PC12h cells.
Journal of biochemistry 1998;123(3):423-30.
1998: T Satoh; Tadahiro Numakawa; Yasuhiro Abiru; T Yamagata; Yasuyuki Ishikawa; Yasushi Enokido; Hiroshi Hatanaka
Production of reactive oxygen species and release of L-glutamate during superoxide anion-induced cell death of cerebellar granule neurons.
Journal of neurochemistry 1998;70(1):316-24.
1997: N Sakai; Masashi Yamada; Tadahiro Numakawa; Akihiko Ogura; Hiroshi Hatanaka
BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons.
Brain research 1997;778(2):318-28.
1997: Masashi Yamada; Hiroshi Ohnishi; S i Sano; Atsutoshi Nakatani; Toshihiko Ikeuchi; Hiroshi Hatanaka
Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.
The Journal of biological chemistry 1997;272(48):30334-9.
1997: T Satoh; Yasushi Enokido; H Aoshima; Yasuo Uchiyama; Hiroshi Hatanaka
Changes in mitochondrial membrane potential during oxidative stress-induced apoptosis in PC12 cells.
Journal of neuroscience research 1997;50(3):413-20.
1997: Yukio Akaneya; Tadaharu Tsumoto; S Kinoshita; Hiroshi Hatanaka
Brain-derived neurotrophic factor enhances long-term potentiation in rat visual cortex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(17):6707-16.
1997: Koji Shimoke; Tateki Kubo; Tadahiro Numakawa; Yasuhiro Abiru; Yasushi Enokido; Nobuyuki Takei; Toshihiko Ikeuchi; Hiroshi Hatanaka
Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons.
Brain research. Developmental brain research 1997;101(1-2):197-206.
1997: Yasushi Enokido; N Inamura; Toshiyuki Araki; T Satoh; H Nakane; Masafumi Yoshino; Yoshimichi Nakatsu; Keiichi Tanaka; Hiroshi Hatanaka
Loss of the xeroderma pigmentosum group A gene (XPA) enhances apoptosis of cultured cerebellar neurons induced by UV but not by low-K+ medium.
Journal of neurochemistry 1997;69(1):246-51.
1997: H Aoshima; T Satoh; Norio Sakai; M Yamada; Yasushi Enokido; Toshihiko Ikeuchi; Hiroshi Hatanaka
Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12h cells.
Biochimica et biophysica acta 1997;1345(1):35-42.
1996: Y Akaneya; Tadaharu Tsumoto; Hiroshi Hatanaka
Brain-derived neurotrophic factor blocks long-term depression in rat visual cortex.
Journal of neurophysiology 1996;76(6):4198-201.
1996: T Oka; T Kubo; Yasushi Enokido; Hiroshi Hatanaka
Expression of cyclin A decreases during neuronal apoptosis in cultured rat cerebellar granule neurons.
Brain research. Developmental brain research 1996;97(1):96-106.
1996: T Nonomura; T Kubo; T Oka; Koji Shimoke; Masashi Yamada; Yasushi Enokido; Hiroshi Hatanaka
Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.
Brain research. Developmental brain research 1996;97(1):42-50.
1996: Tateki Kubo; Yasushi Enokido; Masashi Yamada; T Oka; Yasuo Uchiyama; Hiroshi Hatanaka
Oxygen-induced apoptosis in PC12 cells with special reference to the role of Bcl-2.
Brain research 1996;733(2):175-83.
1996: T Satoh; N Sakai; Yasushi Enokido; Yasuo Uchiyama; Hiroshi Hatanaka
Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells.
Brain research 1996;733(1):9-14.
1996: T Satoh; Norio Sakai; Yasushi Enokido; Y Uchiyama; Hiroshi Hatanaka
Free radical-independent protection by nerve growth factor and Bcl-2 of PC12 cells from hydrogen peroxide-triggered apoptosis.
Journal of biochemistry 1996;120(3):540-6.
1996: Masashi Yamada; Toshihiko Ikeuchi; S Aimoto; Hiroshi Hatanaka
EGF-induced sustained tyrosine phosphorylation and decreased rate of down-regulation of EGF receptor in PC12h-R cells which show neuronal differentiation in response to EGF.
Neurochemical research 1996;21(7):815-22.
1996: Yasuhiro Abiru; Chika Nishio; Hiroshi Hatanaka
The survival of striatal cholinergic neurons cultured from postnatal 2-week-old rats is promoted by neurotrophins.
Brain research. Developmental brain research 1996;91(2):260-7.
1996: Masashi Yamada; Toshihiko Ikeuchi; S Aimoto; Hiroshi Hatanaka
PC12h-R cell, a subclone of PC12 cells, shows EGF-induced neuronal differentiation and sustained signaling.
Journal of neuroscience research 1996;43(3):355-64.
1996: Yasushi Enokido; T Araki; S Aizawa; Hiroshi Hatanaka
p53 involves cytosine arabinoside-induced apoptosis in cultured cerebellar granule neurons.
Neuroscience letters 1996;203(1):1-4.
1995: M Kojima; Toshihiko Ikeuchi; Hiroshi Hatanaka
Role of nerve growth factor in the expression of trkA mRNA in cultured embryonic rat basal forebrain cholinergic neurons.
Journal of neuroscience research 1995;42(6):775-83.
1995: T Satoh; N Sakai; Tateki Kubo; Yasushi Enokido; Y Uchiyama; Hiroshi Hatanaka
Flow cytometric analysis of serum deprivation-induced apoptosis of PC12 cells, with special reference to role of bcl-2.
Neuroscience letters 1995;201(2):119-22.
1995: T Nonomura; Chika Nishio; Ronald Lindsay; Hiroshi Hatanaka
Cultured basal forebrain cholinergic neurons from postnatal rats show both overlapping and non-overlapping responses to the neurotrophins.
Brain research 1995;683(1):129-39.
1995: T Kubo; T Nonomura; Yasushi Enokido; Hiroshi Hatanaka
Brain-derived neurotrophic factor (BDNF) can prevent apoptosis of rat cerebellar granule neurons in culture.
Brain research. Developmental brain research 1995;85(2):249-58.
1994: Masashi Yamada; Toshihiko Ikeuchi; H Tsukui; S Aimoto; Hiroshi Hatanaka
Sustained tyrosine phosphorylation of p140trkA in PC12h-R cells responding rapidly to NGF.
Brain research 1994;661(1-2):137-46.
1994: M Nakamura; Chika Nishio; T Nonomura; Hiroshi Hatanaka
High potassium and cyclic AMP analog promote neuronal survival of basal forebrain cholinergic neurons in culture from postnatal 2-week-old rats.
Brain research. Developmental brain research 1994;81(2):218-29.
1994: Y Akaneya; M Takahashi; Hiroshi Hatanaka
Death of cultured postnatal rat CNS neurons by in vitro hypoxia with special reference to N-methyl-D-aspartate-related toxicity.
Neuroscience research 1994;19(3):279-85.
1994: Masashi Yamada; Hiroshi Hatanaka
Interleukin-6 protects cultured rat hippocampal neurons against glutamate-induced cell death.
Brain research 1994;643(1-2):173-80.
1994: Y Akaneya; M Takahashi; H Tsukui; Hiroshi Hatanaka
Enhancement of choline acetyltransferase activity in coculture of rat septal and hippocampal neurons.
Brain research 1994;642(1-2):38-46.
1994: M Kojima; Toshihiko Ikeuchi; Hiroshi Hatanaka
Nerve growth factor induces trkA mRNA expression in cultured basal forebrain cholinergic neurons from 17-day fetal rats.
Neuroscience letters 1994;169(1-2):47-50.
1993: Yasushi Enokido; Hiroshi Hatanaka
Apoptotic cell death occurs in hippocampal neurons cultured in a high oxygen atmosphere.
Neuroscience 1993;57(4):965-72.
1993: Y Akaneya; Yasushi Enokido; M Takahashi; Hiroshi Hatanaka
In vitro model of hypoxia: basic fibroblast growth factor can rescue cultured CNS neurons from oxygen-deprived cell death.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1993;13(6):1029-32.
1992: Yasushi Enokido; Y Akaneya; M Niinobe; K Mikoshiba; Hiroshi Hatanaka
Basic fibroblast growth factor rescues CNS neurons from cell death caused by high oxygen atmosphere in culture.
Brain research 1992;599(2):261-71.
1992: Y Kushima; Chika Nishio; T Nonomura; Hiroshi Hatanaka
Effects of nerve growth factor and basic fibroblast growth factor on survival of cultured septal cholinergic neurons from adult rats.
Brain research 1992;598(1-2):264-70.
1992: M Kojima; N Takahashi; Toshihiko Ikeuchi; Hiroshi Hatanaka
Nerve growth factor (NGF)-mediated up-regulation of low-affinity NGF receptor gene expression in cultured basal forebrain cholinergic neurons from postnatal 3-day-old rats.
Brain research. Molecular brain research 1992;16(3-4):267-73.
1992: Y Kushima; Hiroshi Hatanaka
Culture of neuronal cells from postnatal rat brain: application to the study of neurotrophic factors.
Progress in neuro-psychopharmacology & biological psychiatry 1992;16(5):617-33.
1992: Y Kushima; Hiroshi Hatanaka
Interleukin-6 and leukemia inhibitory factor promote the survival of acetylcholinesterase-positive neurons in culture from embryonic rat spinal cord.
Neuroscience letters 1992;143(1-2):110-4.
1992: T Nonomura; Hiroshi Hatanaka
Neurotrophic effect of brain-derived neurotrophic factor on basal forebrain cholinergic neurons in culture from postnatal rats.
Neuroscience research 1992;14(3):226-33.
1992: Y Kushima; T Hama; Hiroshi Hatanaka
Interleukin-6 as a neurotrophic factor for promoting the survival of cultured catecholaminergic neurons in a chemically defined medium from fetal and postnatal rat midbrains.
Neuroscience research 1992;13(4):267-80.
1991: T Hama; Y Kushima; M Miyamoto; M Kubota; N Takei; Hiroshi Hatanaka
Interleukin-6 improves the survival of mesencephalic catecholaminergic and septal cholinergic neurons from postnatal, two-week-old rats in cultures.
Neuroscience 1991;40(2):445-52.
1990: Yasushi Enokido; Hiroshi Hatanaka
High oxygen atmosphere for neuronal cell culture with nerve growth factor. II. Survival and growth of clonal rat pheochromocytoma PC12h cells.
Brain research 1990;536(1-2):23-9.
1990: Y Kushima; H Tsukui; Yasushi Enokido; Chika Nishio; Hiroshi Hatanaka
High oxygen atmosphere for neuronal cell culture with nerve growth factor. I. Primary culture of basal forebrain cholinergic neurons from fetal and postnatal rats.
Brain research 1990;536(1-2):16-22.
1990: Kazuhiro Ikenaka; Kensuke Nakahira; C Takayama; K Wada; Hiroshi Hatanaka; K Mikoshiba
Nerve growth factor rapidly induces expression of the 68-kDa neurofilament gene by posttranscriptional modification in PC12h-R cells.
The Journal of biological chemistry 1990;265(32):19782-5.
1990: N Takei; H Tsukui; K Kumakura; Hiroshi Hatanaka
Monitoring of acetylcholine released from postnatal rat basal forebrain cholinergic neurons cultured on membrane filter by cell bed perfusion system and HPLC-ECD.
Experimental neurology 1990;108(3):229-31.
1990: Hiroshi Hatanaka; Chika Nishio; Y Kushima; H Tsukui
Nerve-growth-factor-dependent and cell-density-independent survival of septal cholinergic neurons in culture from postnatal rats.
Neuroscience research 1990;8(2):69-82.
1989: K Hisanaga; K Kogure; H Tsukui; N Takei; Chika Nishio; Hiroshi Hatanaka
Increase in choline acetyltransferase activity in septum of rats after transient forebrain ischemia: a possible role of factors released in the hippocampus.
Neuroscience letters 1989;105(3):321-5.
1989: N Takei; H Tsukui; Hiroshi Hatanaka
Intracellular storage and evoked release of acetylcholine from postnatal rat basal forebrain cholinergic neurons in culture with nerve growth factor.
Journal of neurochemistry 1989;53(5):1405-10.
1989: T Hama; M Miyamoto; H Tsukui; Chika Nishio; Hiroshi Hatanaka
Interleukin-6 as a neurotrophic factor for promoting the survival of cultured basal forebrain cholinergic neurons from postnatal rats.
Neuroscience letters 1989;104(3):340-4.
1989: S Ikegami; I Nihonmatsu; Hiroshi Hatanaka; N Takei; H Kawamura
Transplantation of septal cholinergic neurons to the hippocampus improves memory impairments of spatial learning in rats treated with AF64A.
Brain research 1989;496(1-2):321-6.
1989: S Ikegami; I Nihonmatsu; Hiroshi Hatanaka; N Takei; H Kawamura
Recovery of hippocampal cholinergic activity by transplantation of septal neurons in AF64A treated rats.
Neuroscience letters 1989;101(1):17-22.
1989: Y Arimatsu; M Miyamoto; H Tsukui; Hiroshi Hatanaka
Nerve growth factor promotes survival of retrogradely labeled hippocampus-projecting neurons in the rat basal forebrain in vitro.
Brain research. Developmental brain research 1989;45(2):297-301.
1988: K Hisanaga; H Tsukui; N Takei; Hiroshi Hatanaka
Transplantation of fetal and early postnatal rat septal cholinergic neurons cultured in serum-free and serum-containing medium with nerve growth factor.
Brain research 1988;475(2):349-55.
1988: N Takei; H Tsukui; Hiroshi Hatanaka
Nerve growth factor increases the intracellular content of acetylcholine in cultured septal neurons from developing rats.
Journal of neurochemistry 1988;51(4):1118-25.
1988: Y Kubota; Shinobu Inagaki; S Kito; S Shimada; T Okayama; Hiroshi Hatanaka; G Pelletier; H Takagi; Masaya Tohyama
Neuropeptide Y-immunoreactive neurons receive synaptic inputs from dopaminergic axon terminals in the rat neostriatum.
Brain research 1988;458(2):389-93.
1988: Hiroshi Hatanaka; I Nihonmatsu; H Tsukui
Nerve growth factor promotes survival of cultured magnocellular cholinergic neurons from nucleus basalis of Meynert in postnatal rats.
Neuroscience letters 1988;90(1-2):63-8.
1988: Hiroshi Hatanaka; H Tsukui; I Nihonmatsu
Developmental change in the nerve growth factor action from induction of choline acetyltransferase to promotion of cell survival in cultured basal forebrain cholinergic neurons from postnatal rats.
Brain research 1988;467(1):85-95.
1987: Hiroshi Hatanaka
[Effect of NGF on septal cholinergic neurons in culture].
Yakubutsu, seishin, kōdō = Japanese journal of psychopharmacology 1987;7(4):467-70.
1987: Hiroshi Hatanaka; H Tsukui; I Nihonmatsu
Septal cholinergic neurons from postnatal rat can survive in the dissociate culture conditions in the presence of nerve growth factor.
Neuroscience letters 1987;79(1-2):85-90.