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Hansjörg Hauser

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Peter P Mueller; Sylvia Arnold; Friedrich-Wilhelm Bach; Muhammad Badar; Dirk Bormann; Andreas Drynda; Hansjörg Hauser; Andrea Meyer-Lindenberg; Matthias Peuster
Histological and molecular evaluation of iron as degradable medical implant material in a murine animal model.
L Botezatu; L Gama-Norton; Hansjörg Hauser; Roland Schucht; S Sievers; Dagmar Wirth
Genetic aspects of cell line development from a synthetic biology perspective.
Antje Ksienzyk; Ramya Nandakumar; Berit Neumann; Rainer Zawatzky; Günter Bernhardt; Katja Finsterbusch; Martina Grashoff; Hansjörg Hauser; Andrea Kröger
IRF-1 expression is essential for natural killer cells to suppress metastasis.

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2012: Peter P Mueller; Sylvia Arnold; Friedrich-Wilhelm Bach; Muhammad Badar; Dirk Bormann; Andreas Drynda; Hansjörg Hauser; Andrea Meyer-Lindenberg; Matthias Peuster
Histological and molecular evaluation of iron as degradable medical implant material in a murine animal model.
Journal of biomedical materials research. Part A 2012;100(11):2881-9.
2012: L Botezatu; L Gama-Norton; Hansjörg Hauser; Roland Schucht; S Sievers; Dagmar Wirth
Genetic aspects of cell line development from a synthetic biology perspective.
Advances in biochemical engineering/biotechnology 2012;127():251-84.
2011: Antje Ksienzyk; Ramya Nandakumar; Berit Neumann; Rainer Zawatzky; Günter Bernhardt; Katja Finsterbusch; Martina Grashoff; Hansjörg Hauser; Andrea Kröger
IRF-1 expression is essential for natural killer cells to suppress metastasis.
Cancer research 2011;71(20):6410-8.
2011: Manuel Carrondo; Amos Panet; Dagmar Wirth; Ana S Coroadinha; Pedro Cruz; Haya Falk; Roland Schucht; Francis Dupont; Cécile Geny-Fiamma; Otto-Wilhelm Merten; Hansjörg Hauser
Integrated strategy for the production of therapeutic retroviral vectors.
Human gene therapy 2011;22(3):370-9.
2011: U Sandhu; M Cebula; S Behme; P Riemer; C Wodarczyk; D Metzger; Jörg Reimann; R Schirmbeck; Hansjörg Hauser; Dagmar Wirth
Strict control of transgene expression in a mouse model for sensitive biological applications based on RMCE compatible ES cells.
Nucleic acids research 2011;39(1):e1.
2010: Julia Elisabeth Pulverer; Ulfert Rand; Stefan Lienenklaus; Daniela Kugel; Natalia Zietara; Georg Kochs; Ronald Naumann; Siegfried Weiss; Peter Staeheli; Hansjörg Hauser; Mario Köster
Temporal and spatial resolution of type I and III interferon responses in vivo.
Journal of virology 2010;84(17):8626-38.
2010: L Gama-Norton; S Herrmann; Roland Schucht; A S Coroadinha; R Löw; P M Alves; C C Bartholomae; M Schmidt; C Baum; A Schambach; Hansjörg Hauser; Dagmar Wirth
Retroviral vector performance in defined chromosomal Loci of modular packaging cell lines.
Human gene therapy 2010;21(8):979-91.
2010: Nicole Dietrich; Manfred Rohde; Robert Geffers; Andrea Kröger; Hansjörg Hauser; Siegfried Weiss; Nelson O Gekara
Mast cells elicit proinflammatory but not type I interferon responses upon activation of TLRs by bacteria.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(19):8748-53.
2010: K Nehlsen; S Herrmann; J Zauers; Hansjörg Hauser; Dagmar Wirth
Toxin-antitoxin based transgene expression in mammalian cells.
Nucleic acids research 2010;38(5):e32.
2010: Tobias May; Milada Butueva; Sara Bantner; David Markusic; Jurgen Seppen; Roderick A F MacLeod; Herbert Weich; Hansjörg Hauser; Dagmar Wirth
Synthetic gene regulation circuits for control of cell expansion.
Tissue engineering. Part A 2010;16(2):441-52.
2010: Muhammad Badar; Katherina Hemmen; Manfred Nimtz; Martin Stieve; Meike Stiesch; Thomas Lenarz; Hansjörg Hauser; Ute Möllmann; Sebastian Vogt; Matthias Schnabelrauch; Peter P Mueller
Evaluation of madurahydroxylactone as a slow release antibacterial implant coating.
The open biomedical engineering journal 2010;4():263-70.
2009: Peter P Mueller; Andreas Drynda; Diane Goltz; René Hoehn; Hansjörg Hauser; Matthias Peuster
Common signatures for gene expression in postnatal patients with patent arterial ducts and stented arteries.
Cardiology in the young 2009;19(4):352-9.
2009: Kristina Nehlsen; Roland Schucht; Leonor da Gama-Norton; Wolfgang Krömer; Alexandra Baer; Aziz Cayli; Hansjörg Hauser; Dagmar Wirth
Recombinant protein expression by targeting pre-selected chromosomal loci.
BMC biotechnology 2009;9():100.
2008: Tobias May; Lee Eccleston; Sabrina Herrmann; Hansjörg Hauser; Jorge Goncalves; Dagmar Wirth
Bimodal and hysteretic expression in mammalian cells from a synthetic gene circuit.
PloS one 2008;3(6):e2372.
2007: Dagmar Wirth; Leonor Gama-Norton; Pamela Riemer; Upneet Sandhu; Roland Schucht; Hansjörg Hauser
Road to precision: recombinase-based targeting technologies for genome engineering.
Current opinion in biotechnology 2007;18(5):411-9.
2007: Andrea Kröger; Anja Stirnweiss; Julia Elisabeth Pulverer; Katjana Klages; Martina Grashoff; Jörg Reimann; Hansjörg Hauser
Tumor suppression by IFN regulatory factor-1 is mediated by transcriptional down-regulation of cyclin D1.
Cancer research 2007;67(7):2972-81.
2007: Tobias May; Hansjörg Hauser; Dagmar Wirth
In vitro expansion of tissue cells by conditional proliferation.
Methods in molecular medicine 2007;140():1-15.
2007: Natalie Dror; Michal Alter-Koltunoff; Aviva Azriel; Ninette Amariglio; Jasmine Jacob-Hirsch; Sharon Zeligson; Avigail Morgenstern; Tomohiko Tamura; Hansjörg Hauser; Gideon Rechavi; Keiko Ozato; Ben-Zion Levi
Identification of IRF-8 and IRF-1 target genes in activated macrophages.
Molecular immunology 2007;44(4):338-46.
2006: Reinhold Schirmbeck; Petra Riedl; Mark Kupferschmitt; Ursula Wegenka; Hansjörg Hauser; Jason Rice; Andrea Kröger; Jörg Reimann
Priming protective CD8 T cell immunity by DNA vaccines encoding chimeric, stress protein-capturing tumor-associated antigen.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1534-42.
2006: Roland Schucht; Ana S Coroadinha; M A Zanta-Boussif; Els Verhoeyen; Manuel J T Carrondo; Hansjörg Hauser; Dagmar Wirth
A new generation of retroviral producer cells: predictable and stable virus production by Flp-mediated site-specific integration of retroviral vectors.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;14(2):285-92.
2006: Ana S Coroadinha; Roland Schucht; L Gama-Norton; Dagmar Wirth; Hansjörg Hauser; Manuel J T Carrondo
The use of recombinase mediated cassette exchange in retroviral vector producer cell lines: predictability and efficiency by transgene exchange.
Journal of biotechnology 2006;124(2):457-68.
2006: Wilfried Kues; Reinhard Schwinzer; Dagmar Wirth; Els Verhoeyen; Erika Lemme; Doris Herrmann; Brigitte Barg-Kues; Hansjörg Hauser; Kurt Wonigeit; Heiner Niemann
Epigenetic silencing and tissue independent expression of a novel tetracycline inducible system in double-transgenic pigs.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1200-2.
2006: Thomas Frahm; Hansjörg Hauser; Mario Köster
IFN-type-I-mediated signaling is regulated by modulation of STAT2 nuclear export.
Journal of cell science 2006;119(Pt 6):1092-104.
2006: Tobias May; Hansjörg Hauser; Dagmar Wirth
Current status of transcriptional regulation systems.
Cytotechnology 2006;50(1-3):109-19.
2006: Natali Froese; Michael Schwarzer; Ina Niedick; Ursula Frischmann; Mario Köster; Andrea Kröger; Peter P Mueller; Mahtab Nourbakhsh; Bastian Pasche; Jörg Reimann; Peter Staeheli; Hansjörg Hauser
Innate immune responses in NF-kappaB-repressing factor-deficient mice.
Molecular and cellular biology 2006;26(1):293-302.
2005: Tobias May; Peter P Mueller; Herbert A Weich; Natali Froese; Urban Deutsch; Dagmar Wirth; Andrea Kröger; Hansjörg Hauser
Establishment of murine cell lines by constitutive and conditional immortalization.
Journal of biotechnology 2005;120(1):99-110.
2005: Christofer V Samuelsson; Stefan Lienenklaus; Peter P Müller; Rainer Zawatzky; Hansjörg Hauser; Siegfried Weiss
Transformation of mouse fibroblasts alters the induction pattern of type I IFNs after virus infection.
Biochemical and biophysical research communications 2005;335(2):584-9.
2005: Tobias May; Dagmar Wirth; Hansjörg Hauser; Peter P Mueller
Transcriptionally regulated immortalization overcomes side effects of temperature-sensitive SV40 large T antigen.
Biochemical and biophysical research communications 2005;327(3):734-41.
2005: Mario Köster; Thomas Frahm; Hansjörg Hauser
Nucleocytoplasmic shuttling revealed by FRAP and FLIP technologies.
Current opinion in biotechnology 2005;16(1):28-34.
2005: Nektarios Dikopoulos; Antonio Bertoletti; Andrea Kröger; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann
Type I IFN negatively regulates CD8+ T cell responses through IL-10-producing CD4+ T regulatory 1 cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(1):99-109.
2004: Ina Niedick; Natali Froese; André Oumard; Peter P Mueller; Mahtab Nourbakhsh; Hansjörg Hauser; Mario Köster
Nucleolar localization and mobility analysis of the NF-kappaB repressing factor NRF.
Journal of cell science 2004;117(Pt 16):3447-58.
2004: Jacqueline Unsinger; Werner Lindenmaier; Tobias May; Hansjörg Hauser; Dagmar Wirth
Stable and strictly controlled expression of LTR-flanked autoregulated expression cassettes upon adenoviral transfer.
Biochemical and biophysical research communications 2004;319(3):879-87.
2004: Nektarios Dikopoulos; Ursula Wegenka; Andrea Kröger; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann
Recently primed CD8+ T cells entering the liver induce hepatocytes to interact with naïve CD8+ T cells in the mouse.
Hepatology (Baltimore, Md.) 2004;39(5):1256-66.
2004: Ieva Jomantaite; Nektarios Dikopoulos; Andrea Kröger; Frank Leithäuser; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann
Hepatic dendritic cell subsets in the mouse.
European journal of immunology 2004;34(2):355-65.
2004: Tobias May; Hansjörg Hauser; Dagmar Wirth
Transcriptional control of SV40 T-antigen expression allows a complete reversion of immortalization.
Nucleic acids research 2004;32(18):5529-38.
2004: Dagmar Wirth; Hansjörg Hauser
Flp-mediated integration of expression cassettes into FRT-tagged chromosomal loci in mammalian cells.
Methods in molecular biology (Clifton, N.J.) 2004;267():467-76.
2003: Michal Alter-Koltunoff; Sharon Ehrlich; Natalie Dror; Aviva Azriel; Martin Eilers; Hansjörg Hauser; Holly Bowen; C Howard Barton; Tomohiko Tamura; Keiko Ozato; Ben-Zion Levi
Nramp1-mediated innate resistance to intraphagosomal pathogens is regulated by IRF-8, PU.1, and Miz-1.
The Journal of biological chemistry 2003;278(45):44025-32.
2003: Mario Köster; Søren Lykke-Andersen; Yasser A Elnakady; Klaus Gerth; Peter Washausen; Gerhard Höfle; Florenz Sasse; Jørgen Kjems; Hansjörg Hauser
Ratjadones inhibit nuclear export by blocking CRM1/exportin 1.
Experimental cell research 2003;286(2):321-31.
2003: Dirk Spitzer; Kurt E J Dittmar; Manfred Rohde; Hansjörg Hauser; Dagmar Wirth
Green fluorescent protein-tagged retroviral envelope protein for analysis of virus-cell interactions.
Journal of virology 2003;77(10):6070-5.
2003: Andrea Kröger; Andreas Dallügge; Sabine Kirchhoff; Hansjörg Hauser
IRF-1 reverts the transformed phenotype of oncogenically transformed cells in vitro and in vivo.
Oncogene 2003;22(7):1045-56.
2003: Marcin Kwissa; Andrea Kröger; Hansjörg Hauser; Jörg Reimann; Reinhold Schirmbeck
Cytokine-facilitated priming of CD8+ T cell responses by DNA vaccination.
Journal of molecular medicine (Berlin, Germany) 2003;81(2):91-101.
2002: David Meraro; Merav Gleit-Kielmanowicz; Hansjörg Hauser; Ben-Zion Levi
IFN-stimulated gene 15 is synergistically activated through interactions between the myelocyte/lymphocyte-specific transcription factors, PU.1, IFN regulatory factor-8/IFN consensus sequence binding protein, and IFN regulatory factor-4: characterization of a new subtype of IFN-stimulated response element.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6224-31.
2002: Katharina Schroeder; Steffen Koschmieder; Oliver G Ottmann; Dieter Hoelzer; Hansjörg Hauser; Peter P Mueller
Coordination of cell growth in cocultures by a genetic proliferation control system.
Biotechnology and bioengineering 2002;78(3):346-52.
2002: Zlatko Trobonjaca; Andrea Kröger; Detlef Stober; Frank Leithäuser; Peter Möller; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann
Activating immunity in the liver. II. IFN-beta attenuates NK cell-dependent liver injury triggered by liver NKT cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):3763-70.
2002: F Hirschmann; Els Verhoeyen; Dagmar Wirth; S Bauwens; Hansjörg Hauser; Maximilian Rudert
Vital marking of articular chondrocytes by retroviral infection using green fluorescence protein.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2002;10(2):109-18.
2002: Andrea Kröger; Mario Köster; Katharina Schroeder; Hansjörg Hauser; Peter P Mueller
Activities of IRF-1.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2002;22(1):5-14.
2001: Heiner Niemann; Els Verhoeyen; Kurt Wonigeit; Ralf Lorenz; Jens M Hecker; Reinhard Schwinzer; Hansjörg Hauser; Wilfried Kues; R Halter; Erika Lemme; Doris Herrmann; Michael Winkler; Dagmar Wirth; D Paul
Cytomegalovirus early promoter induced expression of hCD59 in porcine organs provides protection against hyperacute rejection.
Transplantation 2001;72(12):1898-906.
2001: Jacqueline Unsinger; Andrea Kröger; Hansjörg Hauser; Dagmar Wirth
Retroviral vectors for the transduction of autoregulated, bidirectional expression cassettes.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(5):484-9.
2001: M Hennecke; Marcin Kwissa; K Metzger; André Oumard; Andrea Kröger; R Schirmbeck; Jörg Reimann; Hansjörg Hauser
Composition and arrangement of genes define the strength of IRES-driven translation in bicistronic mRNAs.
Nucleic acids research 2001;29(16):3327-34.
2001: Els Verhoeyen; Hansjörg Hauser; Dagmar Wirth
Evaluation of retroviral vector design in defined chromosomal loci by Flp-mediated cassette replacement.
Human gene therapy 2001;12(8):933-44.
2001: Andrea Kröger; Dörte Ortmann; Tim Krohne; Leonhard Mohr; Hubert E Blum; Hansjörg Hauser; Michael Geissler
Growth suppression of the hepatocellular carcinoma cell line Hepa1-6 by an activatable interferon regulatory factor-1 in mice.
Cancer research 2001;61(6):2609-17.
2001: Mahtab Nourbakhsh; S Kalble; A Dorrie; Hansjörg Hauser; Klaus Resch; Michael Kracht
The NF-kappa b repressing factor is involved in basal repression and interleukin (IL)-1-induced activation of IL-8 transcription by binding to a conserved NF-kappa b-flanking sequence element.
The Journal of biological chemistry 2001;276(6):4501-8.
2000: Sabine Kirchhoff; André Oumard; Mahtab Nourbakhsh; Ben-Zion Levi; Hansjörg Hauser
Interplay between repressing and activating domains defines the transcriptional activity of IRF-1.
European journal of biochemistry / FEBS 2000;267(23):6753-61.
2000: Mahtab Nourbakhsh; André Oumard; Michael Schwarzer; Hansjörg Hauser
NRF, a nuclear inhibitor of NF-kappaB proteins silencing interferon-beta promoter.
European cytokine network 2000;11(3):500-1.
2000: C Geserick; H P Bonarius; L Kongerslev; Hansjörg Hauser; Peter P Mueller
Enhanced productivity during controlled proliferation of BHK cells in continuously perfused bioreactors.
Biotechnology and bioengineering 2000;69(3):266-74.
2000: André Oumard; M Hennecke; Hansjörg Hauser; Mahtab Nourbakhsh
Translation of NRF mRNA is mediated by highly efficient internal ribosome entry.
Molecular and cellular biology 2000;20(8):2755-9.
2000: Ana V Carvalhal; JL Moreira; Helder J Cruz; P Mueller; Hansjörg Hauser; Manuel J T Carrondo
Manipulation of culture conditions for BHK cell growth inhibition by IRF-1 activation.
Cytotechnology 2000;32(2):135-45.
2000: Reinhold Schirmbeck; J von Kampen; K Metzger; Jens Wild; B Grüner; M Schleef; A Kröger; Hansjörg Hauser; Jörg Reimann
DNA-Based Vaccination with Polycistronic Expression Plasmids.
Methods in molecular medicine 2000;29():313-22.
2000: Marcin Kwissa; J Unsinger; Reinhold Schirmbeck; Hansjörg Hauser; Jörg Reimann
Polyvalent DNA vaccines with bidirectional promoters.
Journal of molecular medicine (Berlin, Germany) 2000;78(9):495-506.
2000: Hansjörg Hauser; Dirk Spitzer; Els Verhoeyen; Jacqueline Unsinger; Dagmar Wirth
New approaches towards ex vivo and in vivo gene therapy.
Cells, tissues, organs 2000;167(2-3):75-80.
2000: H Kollmus; Hansjörg Hauser
Frameshifting assay to characterize RNA-protein interactions in eukaryotic cells.
Methods in enzymology 2000;318():363-74.
1999: David Meraro; Sharon Hashmueli; B Koren; Aviva Azriel; André Oumard; Sabine Kirchhoff; Hansjörg Hauser; Sujatha Nagulapalli; Michael L Atchison; Ben-Zion Levi
Protein-protein and DNA-protein interactions affect the activity of lymphoid-specific IFN regulatory factors.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6468-78.
1999: Peter P Mueller; P Schlenke; Manfred Nimtz; Harald S Conradt; Hansjörg Hauser
Recombinant glycoprotein product quality in proliferation-controlled BHK-21 cells.
Biotechnology and bioengineering 1999;65(5):529-36.
1999: Mahtab Nourbakhsh; Hansjörg Hauser
Constitutive silencing of IFN-beta promoter is mediated by NRF (NF-kappaB-repressing factor), a nuclear inhibitor of NF-kappaB.
The EMBO journal 1999;18(22):6415-25.
1999: Dirk Spitzer; Hansjörg Hauser; Dagmar Wirth
Complement-protected amphotropic retroviruses from murine packaging cells.
Human gene therapy 1999;10(11):1893-902.
1999: Sabine Kirchhoff; Hansjörg Hauser
Cooperative activity between HER oncogenes and the tumor suppressor IRF-1 results in apoptosis.
Oncogene 1999;18(25):3725-36.
1999: Sabine Kirchhoff; Dagmar Wilhelm; P Angel; Hansjörg Hauser
NFkappaB activation is required for interferon regulatory factor-1-mediated interferon beta induction.
European journal of biochemistry / FEBS 1999;261(2):546-54.
1999: Mario Köster; Hansjörg Hauser
Dynamic redistribution of STAT1 protein in IFN signaling visualized by GFP fusion proteins.
European journal of biochemistry / FEBS 1999;260(1):137-44.
1998: F Schaper; Sabine Kirchhoff; Guido Posern; Mario Köster; André Oumard; Rekefet Sharf; Ben-Zion Levi; Hansjörg Hauser
Functional domains of interferon regulatory factor I (IRF-1).
The Biochemical journal 1998;335 ( Pt 1)():147-57.
1998: Sabine Kirchhoff; F Schaper; André Oumard; Hansjörg Hauser
In vivo formation of IRF-1 homodimers.
Biochimie 1998;80(8-9):659-64.
1998: Jens Wild; B Grüner; K Metzger; A Kuhröber; HP Pudollek; Hansjörg Hauser; Reinhold Schirmbeck; Jörg Reimann
Polyvalent vaccination against hepatitis B surface and core antigen using a dicistronic expression plasmid.
Vaccine 1998;16(4):353-60.
1997: Mahtab Nourbakhsh; Hansjörg Hauser
The transcriptional silencer protein NRF: a repressor of NF-kappa B enhancers.
Immunobiology 1997;198(1-3):65-72.
1997: Rekefet Sharf; David Meraro; Aviva Azriel; A M Thornton; Keiko Ozato; E F Petricoin; A C Larner; F Schaper; Hansjörg Hauser; Ben-Zion Levi
Phosphorylation events modulate the ability of interferon consensus sequence binding protein to interact with interferon regulatory factors and to bind DNA.
The Journal of biological chemistry 1997;272(15):9785-92.
1996: Sabine Kirchhoff; Mario Köster; Andrea Kröger; F Schaper; M Tümmler; H Cruz; Hansjörg Hauser
Regulation of cell growth by IRF-1 in BHK-21 cells.
Cytotechnology 1996;22(1-3):147-56.
1995: Sabine Kirchhoff; Antonis E Koromilas; F Schaper; M Grashoff; Nahum Sonenberg; Hansjörg Hauser
IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR.
Oncogene 1995;11(3):439-45.
1995: Sabine Kirchhoff; M Köster; M Wirth; F Schaper; Manfred Gossen; H Bujard; Hansjörg Hauser
Identification of mammalian cell clones exhibiting highly regulated expression from inducible promoters.
Trends in genetics : TIG 1995;11(6):219-20.
1994: W Dirks; F Schaper; Hansjörg Hauser
A new hybrid promoter directs transcription at identical start points in mammalian cells and in vitro.
Gene 1994;149(2):389-90.
1994: W Dirks; F Schaper; Sabine Kirchhoff; C Morelle; Hansjörg Hauser
A multifunctional vector family for gene expression in mammalian cells.
Gene 1994;149(2):387-8.
1993: Sabine Kirchhoff; F Schaper; Hansjörg Hauser
Interferon regulatory factor 1 (IRF-1) mediates cell growth inhibition by transactivation of downstream target genes.
Nucleic acids research 1993;21(12):2881-9.
1989: W Eichner; V Jäger; D Herbst; Hansjörg Hauser; Jürgen Hoppe
Large-scale preparation of recombinant platelet-derived growth factor AA secreted from recombinant baby hamster kidney cells.
European journal of biochemistry / FEBS 1989;185(1):135-40.