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David Hawke

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Weiwei Yang; Yan Xia; Dongming Xing; Kenneth Aldape; W K Alfred Yung; David Hawke; Tony Hunter; Xinjian Li; Ji Liang; Zhimin Lu
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
Haitao Ji; Bing-Hua Jiang; Zhiyong Ding; David Hawke; Gordon B Mills; Dongming Xing; Zhimin Lu
AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis.
Yanhua Zheng; David Hawke; David X Liu; Yan Xia; Weiwei Yang; Zhimin Lu
Ras-induced and extracellular signal-regulated kinase 1 and 2 phosphorylation-dependent isomerization of protein tyrosine phosphatase (PTP)-PEST by PIN1 promotes FAK dephosphorylation by PTP-PEST.

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All Publications

2012: Weiwei Yang; Yan Xia; Dongming Xing; Kenneth Aldape; W K Alfred Yung; David Hawke; Tony Hunter; Xinjian Li; Ji Liang; Zhimin Lu
PKM2 phosphorylates histone H3 and promotes gene transcription and tumorigenesis.
Cell 2012;150(4):685-96.
2012: Haitao Ji; Bing-Hua Jiang; Zhiyong Ding; David Hawke; Gordon B Mills; Dongming Xing; Zhimin Lu
AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis.
EMBO reports 2012;13(6):554-60.
2011: Yanhua Zheng; David Hawke; David X Liu; Yan Xia; Weiwei Yang; Zhimin Lu
Ras-induced and extracellular signal-regulated kinase 1 and 2 phosphorylation-dependent isomerization of protein tyrosine phosphatase (PTP)-PEST by PIN1 promotes FAK dephosphorylation by PTP-PEST.
Molecular and cellular biology 2011;31(21):4258-69.
2011: Kenji Yokoi; David Hawke; Carol J Oborn; Jin-Young Jang; Yasuhiko Nishioka; Dominic Fan; Seung Wook Kim; Sun-Jin Kim; Isaiah J Fidler
Identification and validation of SRC and phospho-SRC family proteins in circulating mononuclear cells as novel biomarkers for pancreatic cancer.
Translational oncology 2011;4(2):83-91.
2009: haitao ji; Ji Wang; Heinz Nika; David Hawke; Susan Keezer; Qingyuan Ge; Bingliang Fang; Xuexun Fang; Dexing Fang; David W Litchfield; Kenneth Aldape; Zhimin Lu
EGF-induced ERK activation promotes CK2-mediated disassociation of alpha-Catenin from beta-Catenin and transactivation of beta-Catenin.
Molecular cell 2009;36(4):547-59.
2009: Yanhua Zheng; Yan Xia; David Hawke; Maxime Halle; Michel L Tremblay; Xiang Gao; Xiao Zhen Zhou; Kenneth Aldape; Melanie H Cobb; Keping Xie; Jie He; Zhimin Lu
FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST.
Molecular cell 2009;35(1):11-25.
2009: Hehua Chen; Yan Xia; Dexing Fang; David Hawke; Zhimin Lu
Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis.
Molecular and cellular biology 2009;29(13):3657-64.
2009: Yunsen Li; Prakash Thapa; David Hawke; Yuji Kondo; Keiko Furukawa; Koichi Furukawa; Fong-Fu Hsu; Dietlind Adlercreutz; Joel Weadge; Monica M Palcic; Peng G Wang; Steven B Levery; Dapeng Zhou
Immunologic glycosphingolipidomics and NKT cell development in mouse thymus.
Journal of proteome research 2009;8(6):2740-51.
2008: Cecilia G Clement; Scott E Evans; Christopher M Evans; David Hawke; Ryuji Kobayashi; Paul R Reynolds; Seyed J Moghaddam; Brenton L Scott; Ernestina Melicoff; Roberto Adachi; Burton F Dickey; Michael J Tuvim
Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice.
American journal of respiratory and critical care medicine 2008;177(12):1322-30.
2007: Dexing Fang; David Hawke; Yanhua Zheng; Yan Xia; Jill Meisenhelder; Heinz Nika; Gordon B Mills; Ryuji Kobayashi; Tony Hunter; Zhimin Lu
Phosphorylation of beta-catenin by AKT promotes beta-catenin transcriptional activity.
The Journal of biological chemistry 2007;282(15):11221-9.
2005: Kenji Yokoi; Li-Chen Nancy Shih; Ryuji Kobayashi; John M Koomen; David Hawke; Donghui Li; Stanley R Hamilton; James L Abbruzzese; Kevin R Coombes; Isaiah J Fidler
Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer.
International journal of oncology 2005;27(5):1361-9.
2005: John M Koomen; David Hawke; Ryuji Kobayashi
Developing an understanding of proteomics: an introduction to biological mass spectrometry.
Cancer investigation 2005;23(1):47-59.
2004: Robert S Bresalier; James C Byrd; David Tessler; Joseph Lebel; John M Koomen; David Hawke; Elizabeth Half; Kai-Feng Liu; Nachman Mazurek
A circulating ligand for galectin-3 is a haptoglobin-related glycoprotein elevated in individuals with colon cancer.
Gastroenterology 2004;127(3):741-8.
2004: Chandrani Chattopadhyay; David Hawke; Ryuji Kobayashi; SANKAR MAITY
Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro.
Nucleic acids research 2004;32(12):3632-41.
2003: Koji Itahana; Krishna P Bhat; Aiwen Jin; Yoko Itahana; David Hawke; Ryuji Kobayashi; Yanping Zhang
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.
Molecular cell 2003;12(5):1151-64.
2003: Matthew Galfione; Weiping Luo; Jeri Kim; David Hawke; Ryuji Kobayashi; Carmen Clapp; Li-Yuan Yu-Lee; Sue-Hwa Lin
Expression and purification of the angiogenesis inhibitor 16-kDa prolactin fragment from insect cells.
Protein expression and purification 2003;28(2):252-8.