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Gregory Hawkins

Research Profile

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Xingnan Li; Wendy C Moore; Dan L Nicolae; Carole Ober; Dara G Torgerson; Sally E Wenzel; Elizabeth J Ampleford; Eugene R Bleecker; William W Busse; Mario Castro; Serpil C Erzurum; Gregory A Hawkins; Timothy Howard; Elliot Israel; Huashi Li; Deborah A Meyers
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
Rebecca E Slager; Gregory A Hawkins; Xingnan Li; Deborah A Meyers; Dirkje S Postma; Eugene R Bleecker
Genetics of asthma susceptibility and severity.
Gregory A Hawkins; Timothy Howard; Huashi Li; Xingnan Li; Deborah A Meyers; Wendy C Moore; Stephen P Peters; Mac B Robinson; Sally E Wenzel; Eugene R Bleecker; William W Busse; Serpil C Erzurum; Annette T Hastie
The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.

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2012: Xingnan Li; Wendy C Moore; Dan L Nicolae; Carole Ober; Dara G Torgerson; Sally E Wenzel; Elizabeth J Ampleford; Eugene R Bleecker; William W Busse; Mario Castro; Serpil C Erzurum; Gregory A Hawkins; Timothy Howard; Elliot Israel; Huashi Li; Deborah A Meyers
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.
The Journal of allergy and clinical immunology 2012;130(4):861-8.e7.
2012: Rebecca E Slager; Gregory A Hawkins; Xingnan Li; Deborah A Meyers; Dirkje S Postma; Eugene R Bleecker
Genetics of asthma susceptibility and severity.
Clinics in chest medicine 2012;33(3):431-43.
2012: Gregory A Hawkins; Timothy Howard; Huashi Li; Xingnan Li; Deborah A Meyers; Wendy C Moore; Stephen P Peters; Mac B Robinson; Sally E Wenzel; Eugene R Bleecker; William W Busse; Serpil C Erzurum; Annette T Hastie
The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.
The Journal of allergy and clinical immunology 2012;130(2):510-5.e1.
2012: Rebecca E Slager; Sally E Wenzel; Yu Ping Yen; Gregory A Hawkins; Deborah A Meyers; Babatunde A Otulana; Stephen P Peters; Eugene R Bleecker
IL-4 receptor polymorphisms predict reduction in asthma exacerbations during response to an anti-IL-4 receptor α antagonist.
The Journal of allergy and clinical immunology 2012;130(2):516-22.e4.
2012: Xingnan Li; Wendy C Moore; W Gerald Teague; Sally E Wenzel; Elizabeth J Ampleford; Eugene R Bleecker; William W Busse; Mario Castro; Serpil C Erzurum; Anne M Fitzpatrick; Benjamin Gaston; Gregory A Hawkins; Timothy Howard; Elliot Israel; Nizar N Jarjour; Huashi Li; Deborah A Meyers
The C11orf30-LRRC32 region is associated with total serum IgE levels in asthmatic patients.
The Journal of allergy and clinical immunology 2012;129(2):575-8, 578.e1-9.
2011: Stanton B Gray; Gregory A Hawkins; Carl D Langefeld; Janice D Wagner; Julie T Ziegler; Timothy Howard
Single-nucleotide polymorphisms in the TNF gene are associated with obesity-related phenotypes in vervet monkeys.
Obesity (Silver Spring, Md.) 2011;19(7):1427-32.
2011: Xingnan Li; Timothy Howard; Wendy C Moore; Elizabeth J Ampleford; Huashi Li; William W Busse; William J Calhoun; Mario Castro; Kian Fan Chung; Serpil C Erzurum; Anne M Fitzpatrick; Benjamin Gaston; Elliot Israel; Nizar N Jarjour; W Gerald Teague; Sally E Wenzel; Stephen P Peters; Gregory A Hawkins; Eugene R Bleecker; Deborah A Meyers
Importance of hedgehog interacting protein and other lung function genes in asthma.
The Journal of allergy and clinical immunology 2011;127(6):1457-65.
2011: Timothy D Howard; Mario Medvedovic; Rebecca Slager; Jing Chen; Wei Cui; Stanton Gray; Gregory A Hawkins; Shuk-Mei Ho; Li Zhang; Janice D Wagner
Epigenetic changes with dietary soy in cynomolgus monkeys.
PloS one 2011;6(10):e26791.
2010: Rebecca E Slager; Gregory A Hawkins; Elizabeth J Ampleford; Alexandra Bowden; Lauren E Stevens; Matthew T Morton; Adrian Tomkinson; Sally E Wenzel; Malinda Longphre; Eugene R Bleecker; Deborah A Meyers
IL-4 receptor α polymorphisms are predictors of a pharmacogenetic response to a novel IL-4/IL-13 antagonist.
The Journal of allergy and clinical immunology 2010;126(4):875-8.
2010: Kimberly R Blish; Kathryn A Clausen; Gregory A Hawkins; A Julian Garvin; Mark C Willingham; Julie C Turner; Frank M Torti; Suzy V Torti
Loss of heterozygosity and SOSTDC1 in adult and pediatric renal tumors.
Journal of experimental & clinical cancer research : CR 2010;29():147.
2010: Alfredo Panebra; Wayne C Wang; Molly M Malone; Demar R G Pitter; Scott T Weiss; Gregory A Hawkins; Stephen B Liggett
Common ADRB2 haplotypes derived from 26 polymorphic sites direct beta2-adrenergic receptor expression and regulation phenotypes.
PloS one 2010;5(7):e11819.
2009: Stanton B Gray; Timothy Howard; Carl D Langefeld; Gregory A Hawkins; Abdoulaye F Diallo; Janice D Wagner
Comparative analyses of single-nucleotide polymorphisms in the TNF promoter region provide further validation for the vervet monkey model of obesity.
Comparative medicine 2009;59(6):580-8.
2009: Gerard H Koppelman; Deborah A Meyers; Timothy D Howard; S Lilly Zheng; Gregory A Hawkins; Elizabeth J Ampleford; Jianfeng Xu; Henk Koning; Marcel Bruinenberg; Ilja M Nolte; Cleo C van Diemen; H Marike Boezen; Wim Timens; Paul A Whittaker; O Colin Stine; Sheila J Barton; John W Holloway; Stephen T Holgate; Penelope E Graves; Fernando D Martinez; Antoon J van Oosterhout; Eugene R Bleecker; Dirkje S Postma
Identification of PCDH1 as a novel susceptibility gene for bronchial hyperresponsiveness.
American journal of respiratory and critical care medicine 2009;180(10):929-35.
2009: Gregory A Hawkins; Ross Lazarus; Richard S Smith; Kelan G Tantisira; Deborah A Meyers; Stephen P Peters; Scott Weiss; Eugene R Bleecker
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids.
The Journal of allergy and clinical immunology 2009;123(6):1376-83.e7.
2009: Alireza Sadeghnejad; Jill Ohar; S Lilly Zheng; David A Sterling; Gregory A Hawkins; Deborah A Meyers; Eugene R Bleecker
Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers.
Respiratory research 2009;10():21.
2008: Mohamed El Gazzar; Barbara K Yoza; Xiaoping Chen; Jean Hu; Gregory A Hawkins; Charles E McCall
G9a and HP1 couple histone and DNA methylation to TNFalpha transcription silencing during endotoxin tolerance.
The Journal of biological chemistry 2008;283(47):32198-208.
2008: Robert J Orlowski; Kenneth S O'Rourke; Irene Olorenshaw; Gregory A Hawkins; Stefan Maas; Dama Laxminarayana
Altered editing in cyclic nucleotide phosphodiesterase 8A1 gene transcripts of systemic lupus erythematosus T lymphocytes.
Immunology 2008;125(3):408-19.
2008: Gregory A Hawkins; Scott Weiss; Eugene R Bleecker
Clinical consequences of ADRbeta2 polymorphisms.
Pharmacogenomics 2008;9(3):349-58.
2008: Kimberly Rose Blish; Wei Wang; Mark C Willingham; Wei Du; Charles E Birse; Surekha R Krishnan; Julie C Brown; Gregory A Hawkins; A Julian Garvin; Ralph B D'Agostino; Frank M Torti; Suzy V Torti
A human bone morphogenetic protein antagonist is down-regulated in renal cancer.
Molecular biology of the cell 2008;19(2):457-64.
2008: Alfredo Panebra; Mary Rose Schwarb; Steven M Swift; Scott Weiss; Eugene R Bleecker; Gregory A Hawkins; Stephen B Liggett
Variable-length poly-C tract polymorphisms of the beta2-adrenergic receptor 3'-UTR alter expression and agonist regulation.
American journal of physiology. Lung cellular and molecular physiology 2008;294(2):L190-5.
2008: Gregory A Hawkins; Deborah A Meyers; Eugene R Bleecker; Allan I Pack
Identification of coding polymorphisms in human circadian rhythm genes PER1, PER2, PER3, CLOCK, ARNTL, CRY1, CRY2 and TIMELESS in a multi-ethnic screening panel.
DNA sequence : the journal of DNA sequencing and mapping 2008;19(1):44-9.
2008: Gregory A Hawkins; Stephen P Peters
Pharmacogenetics of asthma.
Methods in molecular biology (Clifton, N.J.) 2008;448():359-78.
2007: Victor E Ortega; Gregory A Hawkins; Stephen P Peters; Eugene R Bleecker
Pharmacogenetics of the beta 2-adrenergic receptor gene.
Immunology and allergy clinics of North America 2007;27(4):665-84; vii.
2007: Ali Mallakin; Takayuki Sugiyama; Pankaj Taneja; Lauren A Matise; Donna P Frazier; Mayur Choudhary; Gregory A Hawkins; Ralph B D'Agostino; Mark C Willingham; Kazushi Inoue
Mutually exclusive inactivation of DMP1 and ARF/p53 in lung cancer.
Cancer cell 2007;12(4):381-94.
2007: Richard S Smith; Deborah A Meyers; Stephen P Peters; Wendy C Moore; Sally A Wenzel; Eugene R Bleecker; Gregory A Hawkins
Sequence analysis of HSPA1A and HSPA1B in a multi-ethnic study population.
DNA sequence : the journal of DNA sequencing and mapping 2007;18(1):47-53.
2006: Gregory A Hawkins; Kelan G Tantisira; Deborah A Meyers; Elizabeth J Ampleford; Wendy C Moore; Barbara J Klanderman; Stephen B Liggett; Stephen P Peters; Scott Weiss; Eugene R Bleecker
Sequence, haplotype, and association analysis of ADRbeta2 in a multiethnic asthma case-control study.
American journal of respiratory and critical care medicine 2006;174(10):1101-9.
2006: Annette T Hastie; Min Wu; Gayle C Foster; Gregory A Hawkins; Vikas Batra; Katherine A Rybinski; Rosemary Cirelli; James G Zangrilli; Stephen P Peters
Alterations in vasodilator-stimulated phosphoprotein (VASP) phosphorylation: associations with asthmatic phenotype, airway inflammation and beta2-agonist use.
Respiratory research 2006;7():25.
2005: Gregory A Hawkins; Scott Weiss; Eugene R Bleecker
Asthma pharmacogenomics.
Immunology and allergy clinics of North America 2005;25(4):723-42.
2005: Judith A Engeler Dusel; Kathryn P Burdon; Pamela J Hicks; Gregory A Hawkins; Donald W Bowden; Barry I Freedman
Identification of podocin (NPHS2) gene mutations in African Americans with nondiabetic end-stage renal disease.
Kidney international 2005;68(1):256-62.
2004: Thomas C Register; Kathryn P Burdon; Leon Lenchik; Donald W Bowden; Gregory A Hawkins; Barbara J Nicklas; Kurt Lohman; Fang-Chi Hsu; Carl D Langefeld; John Carr
Variability of serum soluble intercellular adhesion molecule-1 measurements attributable to a common polymorphism.
Clinical chemistry 2004;50(11):2185-7.
2004: Gregory A Hawkins; Bao-Li Chang; S Lilly Zheng; Sarah D Isaacs; Kathy E Wiley; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; Jianfeng Xu; William B Isaacs
Mutational analysis of PINX1 in hereditary prostate cancer.
The Prostate 2004;60(4):298-302.
2004: Monica J Basehore; Timothy Howard; Leslie A Lange; Wendy C Moore; Gregory A Hawkins; Patricia L Marshik; Michelle S Harkins; Deborah A Meyers; Eugene R Bleecker
A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects.
The Journal of allergy and clinical immunology 2004;114(1):80-7.
2004: Gregory A Hawkins; Pamela J Amelung; Richard S Smith; Hajo Jongepier; Timothy Howard; Gerard H Koppelman; Deborah A Meyers; Eugene R Bleecker; Dirkje S Postma
Identification of polymorphisms in the human glucocorticoid receptor gene (NR3C1) in a multi-racial asthma case and control screening panel.
DNA sequence : the journal of DNA sequencing and mapping 2004;15(3):167-73.
2003: Bao-Li Chang; S Lilly Zheng; Sarah D Isaacs; A Turner; Gregory A Hawkins; Kathy E Wiley; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer.
British journal of cancer 2003;89(8):1524-9.
2003: Bao-Li Chang; S Lilly Zheng; Sarah D Isaacs; Aubrey Turner; Gregory A Hawkins; Kathy E Wiley; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Polymorphisms in the CYP1A1 gene are associated with prostate cancer risk.
International journal of cancer. Journal international du cancer 2003;106(3):375-8.
2003: Jeannette T Bensen; Carl D Langefeld; Gregory A Hawkins; Linda E Green; Josyf C Mychaleckyj; Catherine S Brewer; Deborah S Kiger; Scott M Binford; Carla J Colicigno; Dax C Allred; Barry I Freedman; Donald W Bowden
Nucleotide variation, haplotype structure, and association with end-stage renal disease of the human interleukin-1 gene cluster.
Genomics 2003;82(2):194-217.
2003: S Lilly Zheng; Josyf C Mychaleckyj; Gregory A Hawkins; Sarah D Isaacs; Kathy E Wiley; Aubrey Turner; Bao-Li Chang; Chris Von Kap-Herr; John D Carpten; Mark J Pettenati; Eugene R Bleecker; Patrick C Walsh; Jeffrey M. Trent; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Evaluation of DLC1 as a prostate cancer susceptibility gene: mutation screen and association study.
Mutation research 2003;528(1-2):45-53.
2003: Scott D Cramer; Bao-Li Chang; Anuradha Rao; Gregory A Hawkins; S Lilly Zheng; Wendy N Wade; Roger T Cooke; Leanne N Thomas; Eugene R Bleecker; William J Catalona; David A Sterling; Deborah A Meyers; Jill Ohar; Jianfeng Xu
Association between genetic polymorphisms in the prostate-specific antigen gene promoter and serum prostate-specific antigen levels.
Journal of the National Cancer Institute 2003;95(14):1044-53.
2003: Zheng Cui; Mark C Willingham; Amy M Hicks; Martha Alexander-Miller; Timothy Howard; Gregory A Hawkins; Mark Steven Miller; Holly M Weir; Wei Du; Cynthia J DeLong
Spontaneous regression of advanced cancer: identification of a unique genetically determined, age-dependent trait in mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6682-7.
2003: Anuradha Rao; Bao-Li Chang; Gregory A Hawkins; Jennifer Hu; Charles J Rosser; craig hall; Deborah A Meyers; Jianfeng Xu; Scott D Cramer
Analysis of G/A polymorphism in the androgen response element I of the PSA gene and its interactions with the androgen receptor polymorphisms.
Urology 2003;61(4):864-9.
2003: Jianfeng Xu; S Lilly Zheng; Akira Komiya; Josyf C Mychaleckyj; Sarah D Isaacs; Baoli Chang; Aubrey R Turner; Charles M Ewing; Kathy E Wiley; Gregory A Hawkins; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs
Common sequence variants of the macrophage scavenger receptor 1 gene are associated with prostate cancer risk.
American journal of human genetics 2003;72(1):208-12.
2002: S Lilly Zheng; Bao-Li Chang; Dennis A Faith; Jill R Johnson; Sarah D Isaacs; Gregory A Hawkins; Aubrey Turner; Kathy E Wiley; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk.
Cancer research 2002;62(22):6485-8.
2002: Timothy Howard; Dirkje S Postma; Gregory A Hawkins; Gerard H Koppelman; S Lilly Zheng; Alicia K S Wysong; Jianfeng Xu; Deborah A Meyers; Eugene R Bleecker
Fine mapping of an IgE-controlling gene on chromosome 2q: Analysis of CTLA4 and CD28.
The Journal of allergy and clinical immunology 2002;110(5):743-51.
2002: Gregory A Hawkins; Scott D Cramer; S Lilly Zheng; Sarah D Isaacs; Kathy E Wiley; Bao-Li Chang; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Sequence variants in the human 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1) gene are not associated with prostate cancer risk.
The Prostate 2002;53(3):175-8.
2002: Gregory A Hawkins; Josyf C Mychaleckyj; S Lilly Zheng; Dennis A Faith; Brian Kelly; Sarah D Isaacs; Kathy E Wiley; Bao-Li Chang; Charles M Ewing; Piroska Bujnovszky; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Germline sequence variants of the LZTS1 gene are associated with prostate cancer risk.
Cancer genetics and cytogenetics 2002;137(1):1-7.
2002: David M Herrington; Timothy Howard; K Bridget Brosnihan; Donald P McDonnell; Xiaolin Li; Gregory A Hawkins; David M Reboussin; Jianfeng Xu; S Lilly Zheng; Deborah A Meyers; Eugene R Bleecker
Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein.
Circulation 2002;105(16):1879-82.
2002: Jianfeng Xu; S Lilly Zheng; Aubrey Turner; Sarah D Isaacs; Kathy E Wiley; Gregory A Hawkins; Bao-Li Chang; Eugene R Bleecker; Patrick C Walsh; Deborah A Meyers; William B Isaacs
Associations between hOGG1 sequence variants and prostate cancer susceptibility.
Cancer research 2002;62(8):2253-7.
2002: David M Herrington; Timothy Howard; Gregory A Hawkins; David M Reboussin; Jianfeng Xu; S Lilly Zheng; K Bridget Brosnihan; Deborah A Meyers; Eugene R Bleecker
Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease.
The New England journal of medicine 2002;346(13):967-74.
2002: Bao-Li Chang; S Lilly Zheng; Gregory A Hawkins; Sarah D Isaacs; Kathy E Wiley; Aubrey Turner; John D Carpten; Eugene R Bleecker; Patrick C Walsh; Jeffrey M. Trent; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility.
Cancer research 2002;62(6):1784-9.
2002: Bao-Li Chang; S Lilly Zheng; Gregory A Hawkins; Sarah D Isaacs; Kathy E Wiley; Aubrey Turner; John D Carpten; Eugene R Bleecker; Patrick C Walsh; Jeffrey M. Trent; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Polymorphic GGC repeats in the androgen receptor gene are associated with hereditary and sporadic prostate cancer risk.
Human genetics 2002;110(2):122-9.
2001: B Chang; S L Zheng; Sarah D Isaacs; Kathy E Wiley; John D Carpten; Gregory A Hawkins; Eugene R Bleecker; Patrick C Walsh; Jeffrey M. Trent; Deborah A Meyers; William B Isaacs; Jianfeng Xu
Linkage and association of CYP17 gene in hereditary and sporadic prostate cancer.
International journal of cancer. Journal international du cancer 2001;95(6):354-9.
2001: Jianfeng Xu; S Lilly Zheng; Gregory A Hawkins; Dennis A Faith; B Kelly; Sarah D Isaacs; Kathy E Wiley; Baoli Chang; Charles M Ewing; Piroska Bujnovszky; John D Carpten; Eugene R Bleecker; Patrick C Walsh; Jeffrey M. Trent; Deborah A Meyers; William B Isaacs
Linkage and association studies of prostate cancer susceptibility: evidence for linkage at 8p22-23.
American journal of human genetics 2001;69(2):341-50.