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Seiji Hayashi

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Masahide Mori; Hiroshi Morishita; Hideji Nakamura; Hiroto Matsuoka; Kenya Yoshida; Yoshihiko Kishima; Zhiwei Zhou; Hiroshi Kida; Toshiki Funakoshi; Sho Goya; Mitsuhiro Yoshida; Toru Kumagai; Isao Tachibana; Yoichi Yamamoto; Ichiro Kawase; Seiji Hayashi
Hepatoma-derived growth factor is involved in lung remodeling by stimulating epithelial growth.
Seiji Hayashi; Kin'ya Abe; Hiroto Matsuoka; Sho Goya; Hiroshi Morishita; Masahide Mori; Toru Arai; Hiroshi Kida; Kazumi Nishino; Yoshito Takeda; Tadashi Osaki; Isao Tachibana; Kentaro Kimura; Soichiro Yokota; Yoshikazu Inoue; Mitsunori Sakatani
Increased level of soluble E-selectin in the serum from patients with idiopathic pulmonary fibrosis.
Akihiro Tsuboi; Yoshihiro Oka; Tadashi Osaki; Toru Kumagai; Isao Tachibana; Seiji Hayashi; Masaki Murakami; Hiroko Nakajima; Olga A Elisseeva; Wu Fei; Tomoki Masuda; Masaki Yasukawa; Yusuke Oji; Manabu Kawakami; Naoki Hosen; Kazuhiro Ikegame; Satoshi Yoshihara; Keiko Udaka; Shin-ichi Nakatsuka; Katsuyuki Aozasa; Ichiro Kawase; Haruo Sugiyama
WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases.

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All Publications

2004: Masahide Mori; Hiroshi Morishita; Hideji Nakamura; Hiroto Matsuoka; Kenya Yoshida; Yoshihiko Kishima; Zhiwei Zhou; Hiroshi Kida; Toshiki Funakoshi; Sho Goya; Mitsuhiro Yoshida; Toru Kumagai; Isao Tachibana; Yoichi Yamamoto; Ichiro Kawase; Seiji Hayashi
Hepatoma-derived growth factor is involved in lung remodeling by stimulating epithelial growth.
American journal of respiratory cell and molecular biology 2004;30(4):459-69.
2004: Seiji Hayashi; Kin'ya Abe; Hiroto Matsuoka; Sho Goya; Hiroshi Morishita; Masahide Mori; Toru Arai; Hiroshi Kida; Kazumi Nishino; Yoshito Takeda; Tadashi Osaki; Isao Tachibana; Kentaro Kimura; Soichiro Yokota; Yoshikazu Inoue; Mitsunori Sakatani
Increased level of soluble E-selectin in the serum from patients with idiopathic pulmonary fibrosis.
Inflammation 2004;28(1):1-5.
2004: Akihiro Tsuboi; Yoshihiro Oka; Tadashi Osaki; Toru Kumagai; Isao Tachibana; Seiji Hayashi; Masaki Murakami; Hiroko Nakajima; Olga A Elisseeva; Wu Fei; Tomoki Masuda; Masaki Yasukawa; Yusuke Oji; Manabu Kawakami; Naoki Hosen; Kazuhiro Ikegame; Satoshi Yoshihara; Keiko Udaka; Shin-ichi Nakatsuka; Katsuyuki Aozasa; Ichiro Kawase; Haruo Sugiyama
WT1 peptide-based immunotherapy for patients with lung cancer: report of two cases.
Microbiology and immunology 2004;48(3):175-84.
2003: Yoshito Takeda; Isao Tachibana; Kenji Miyado; Masatoshi Kobayashi; Toru Miyazaki; Toshiki Funakoshi; Hiromi Kimura; Hiroyuki Yamane; Yoshiyuki Saito; Hiroyuki Goto; Toshiyuki Yoneda; Mitsuhiro Yoshida; Toru Kumagai; Tadashi Osaki; Seiji Hayashi; Ichiro Kawase; Eisuke Mekada
Tetraspanins CD9 and CD81 function to prevent the fusion of mononuclear phagocytes.
The Journal of cell biology 2003;161(5):945-56.
2003: Sho Goya; Hiroto Matsuoka; Masahide Mori; Hiroshi Morishita; Hiroshi Kida; Yoichiro Kobashi; Terufumi Kato; Yoshio Taguchi; Tadashi Osaki; Isao Tachibana; Norihiro Nishimoto; Kazuyuki Yoshizaki; Ichiro Kawase; Seiji Hayashi
Sustained interleukin-6 signalling leads to the development of lymphoid organ-like structures in the lung.
The Journal of pathology 2003;200(1):82-7.
2003: Toshiki Funakoshi; Isao Tachibana; Yoshihiko Hoshida; Hiromi Kimura; Yoshito Takeda; Takashi Kijima; Kazumi Nishino; Hiroyuki Goto; Toshiyuki Yoneda; Toru Kumagai; Tadashi Osaki; Seiji Hayashi; Katsuyuki Aozasa; Ichiro Kawase
Expression of tetraspanins in human lung cancer cells: frequent downregulation of CD9 and its contribution to cell motility in small cell lung cancer.
Oncogene 2003;22(5):674-87.
2002: Yusuke Oji; Shinichiro Miyoshi; Hajime Maeda; Seiji Hayashi; Hiroya Tamaki; Shin-ichi Nakatsuka; Masayuki Yao; Eigo Takahashi; Yoko Nakano; Hirohisa Hirabayashi; Yasushi Shintani; Yoshihiro Oka; Akihiro Tsuboi; Naoki Hosen; Momotaro Asada; Tatsuya Fujioka; Masaki Murakami; Keisuke Kanato; Mari Motomura; Eui Ho Kim; Manabu Kawakami; Kazuhiro Ikegame; Hiroyasu Ogawa; Katsuyuki Aozasa; Ichiro Kawase; Haruo Sugiyama
Overexpression of the Wilms' tumor gene WT1 in de novo lung cancers.
International journal of cancer. Journal international du cancer 2002;100(3):297-303.
2002: Hiroto Matsuoka; Toru Arai; Masahide Mori; Sho Goya; Hiroshi Kida; Hiroshi Morishita; Hiroshi Fujiwara; Isao Tachibana; Tadashi Osaki; Seiji Hayashi
A p38 MAPK inhibitor, FR-167653, ameliorates murine bleomycin-induced pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2002;283(1):L103-12.
2002: Hiroyuku Goto; Tadashi Osaki; Kazumi Nishino; Isao Tachibana; Yoshito Takeda; Toshiyuki Yoneda; Toshiki Funakoshi; Hiromi Kimura; Seiji Hayashi; Hideaki Tahara
Construction and analysis of new vector systems with improved interleukin-18 secretion in a xenogeneic human tumor model.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25 Suppl 1():S35-41.
2001: M Suzuki; H Kimura; Isao Tachibana; Harutoshi Fujimura; Yuji Nakatsuji; Fuminobu Sugai; Ichiro Naba; Masayuki Nakamori; Hiroshi Morishita; Toru Arai; Tadashi Osaki; Seiji Hayashi
Improvement of anti-Hu-associated paraneoplastic sensory neuropathy after chemoradiotherapy in a small cell lung cancer patient.
Internal medicine (Tokyo, Japan) 2001;40(11):1140-3.
2001: H Goto; Tadashi Osaki; Takashi Kijima; Kazumi Nishino; Toru Kumagai; Toshiki Funakoshi; H Kimura; Yoshifumi Takeda; Toshiyuki Yoneda; Isao Tachibana; Seiji Hayashi
Gene therapy utilizing the Cre/loxP system selectively suppresses tumor growth of disseminated carcinoembryonic antigen-producing cancer cells.
International journal of cancer. Journal international du cancer 2001;94(3):414-9.
2001: Motokuni Aoki; Ryuichi Morishita; Seiji Hayashi; Nobuo Jo; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model.
Diabetologia 2001;44(8):1034-42.
2001: Kazuhiro Yamamoto; Ryuichi Morishita; Seiji Hayashi; H Matsushita; Hironori Nakagami; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Contribution of Bcl-2, but not Bcl-xL and Bax, to antiapoptotic actions of hepatocyte growth factor in hypoxia-conditioned human endothelial cells.
Hypertension 2001;37(5):1341-8.
2001: Masahide Mori; Hiroshi Kida; Hiroshi Morishita; Sho Goya; Hiroaki Matsuoka; Toru Arai; Tadashi Osaki; Isao Tachibana; S Yamamoto; Mitsunori Sakatani; M Ito; T Ogura; Seiji Hayashi
Microsatellite instability in transforming growth factor-beta 1 type II receptor gene in alveolar lining epithelial cells of idiopathic pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2001;24(4):398-404.
2001: Kazumi Nishino; Tadashi Osaki; Toru Kumagai; Takashi Kijima; Isao Tachibana; H Goto; T Arai; H Kimura; Toshiki Funakoshi; Yoshifumi Takeda; Yoshiro Tanio; Seiji Hayashi
Adenovirus-mediated gene therapy specific for small cell lung cancer cells using a Myc-Max binding motif.
International journal of cancer. Journal international du cancer 2001;91(6):851-6.
2000: Toru Arai; Kin'ya Abe; Hiroaki Matsuoka; Masasuke Yoshida; Masahide Mori; Sho Goya; Hiroshi Kida; Kazumi Nishino; Tadashi Osaki; Isao Tachibana; Yasufumi Kaneda; Seiji Hayashi
Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo.
American journal of physiology. Lung cellular and molecular physiology 2000;278(5):L914-22.
2000: J Sakuma-Mochizuki; Masasuke Yoshida; Kin'ya Abe; Toru Arai; Masahide Mori; Yasufumi Kaneda; Seiji Hayashi
Changes in pulmonary histology and exfoliated bronchoalveolar cells induced by in vivo introduction of the tumor necrosis factor-alpha gene.
Inflammation 2000;24(1):11-9.
2000: Seiji Hayashi; Ryuichi Morishita; H Matsushita; Hironori Nakagami; Yoshiaki Taniyama; Tadashi Nakamura; Motokuni Aoki; Kazuhiro Yamamoto; Jitsuo Higaki; Toshio Ogihara
Cyclic AMP inhibited proliferation of human aortic vascular smooth muscle cells, accompanied by induction of p53 and p21.
Hypertension 2000;35(1 Pt 2):237-43.
1999: Kin'ya Abe; Toru Arai; Masahide Mori; Hiroshi Kida; Sho Goya; Hiroaki Matsuoka; Tadashi Osaki; Isao Tachibana; Seiji Hayashi
Effects of in vivo soluble selectin gene introduction of lps-induced leukocyte accumulation in the murine lung.
Inflammation 1999;23(6):523-34.
1999: Masasuke Yoshida; J Sakuma-Mochizuki; Kin'ya Abe; Toru Arai; Masahide Mori; Sho Goya; Hiroaki Matsuoka; Seiji Hayashi; Yasufumi Kaneda; Tadamitsu Kishimoto
In vivo gene transfer of an extracellular domain of platelet-derived growth factor beta receptor by the HVJ-liposome method ameliorates bleomycin-induced pulmonary fibrosis.
Biochemical and biophysical research communications 1999;265(2):503-8.
1999: Seiji Hayashi; Ryuichi Morishita; Shun Nakamura; Kazuhiro Yamamoto; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of hepatocyte growth factor, a novel angiogenic growth factor, in peripheral arterial disease: downregulation of HGF in response to hypoxia in vascular cells.
Circulation 1999;100(19 Suppl):II301-8.
1999: Masahide Mori; Toru Arai; T Kijima; J Sakuma-Mochizuki; Kin'ya Abe; T Kumagai; Masasuke Yoshida; K Ueno; S Hosoe; H Ogawa; Seiji Hayashi
[Diffuse alveolar hemorrhage after allogeneic bone marrow transplantation].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 1999;37(11):928-33.
1999: Motokuni Aoki; Ryuichi Morishita; H Matsushita; Seiji Hayashi; Hironori Nakagami; Kazuhiro Yamamoto; Atsushi Moriguchi; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of the p53 tumor suppressor gene results in growth of human aortic vascular smooth muscle cells. Potential role of p53 in regulation of vascular smooth muscle cell growth.
Hypertension 1999;34(2):192-200.
1999: Ryuichi Morishita; Shun Nakamura; Seiji Hayashi; Yoshiaki Taniyama; Atsushi Moriguchi; T Nagano; Mutsuo Taiji; H Noguchi; S Takeshita; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy.
Hypertension 1999;33(6):1379-84.
1999: Masasuke Yoshida; Seiji Hayashi; J Sakuma-Mochizuki; Kin'ya Abe; Toru Arai; Masahide Mori; Sho Goya; Hiroaki Matsuoka; Yasufumi Kaneda; Tadamitsu Kishimoto
Introduction of plasmid DNA and oligonucleotides into lung epithelial cells by the hemagglutinating virus of Japan (HVJ)-liposome method.
Somatic cell and molecular genetics 1999;25(1):49-57.
1998: Shun Nakamura; Ryuichi Morishita; Atsushi Moriguchi; Yoshikage Yo; Y Nakamura; Seiji Hayashi; Kunihiro Matsumoto; K Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Hepatocyte growth factor as a potential index of complication in diabetes mellitus.
Journal of hypertension 1998;16(12 Pt 2):2019-26.
1998: N Nakano; Ryuichi Morishita; Atsushi Moriguchi; Y Nakamura; Seiji Hayashi; Motokuni Aoki; Iwao Kida; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-beta in blood vessels: potential role of HGF in cardiovascular disease.
Hypertension 1998;32(3):444-51.
1998: Ryuichi Morishita; Shingo Yamada; Jitsuo Higaki; Naruya Tomita; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; Seiji Hayashi; Ikunosuke Sakurabayashi; Yasufumi Kaneda; Toshio Ogihara
Conditioned medium from HepG2 cells transfected with human apolipoprotein(a) gene stimulates growth of human vascular smooth muscle cells: effects of overexpression of human apolipoprotein(a) gene.
Hypertension 1998;32(2):215-22.
1998: Naruya Tomita; Ryuichi Morishita; S Tomita; Kazuhiro Yamamoto; Motokuni Aoki; H Matsushita; Seiji Hayashi; Jitsuo Higaki; Toshio Ogihara
Transcription factor decoy for nuclear factor-kappaB inhibits tumor necrosis factor-alpha-induced expression of interleukin-6 and intracellular adhesion molecule-1 in endothelial cells.
Journal of hypertension 1998;16(7):993-1000.
1998: Shun Nakamura; Atsushi Moriguchi; Ryuichi Morishita; Motokuni Aoki; Yoshikage Yo; Seiji Hayashi; N Nakano; Tomohiro Katsuya; S Nakata; S Takami; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
A novel vascular modulator, hepatocyte growth factor (HGF), as a potential index of the severity of hypertension.
Biochemical and biophysical research communications 1998;242(1):238-43.
1998: Ryuichi Morishita; Shun Nakamura; Seiji Hayashi; Motokuni Aoki; H Matsushita; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; Jitsuo Higaki; Toshio Ogihara
Contribution of a vascular modulator, hepatocyte growth factor (HGF), to the pathogenesis of cardiovascular disease.
Journal of atherosclerosis and thrombosis 1998;4(3):128-34.
1998: H Matsushita; Ryuichi Morishita; Iwao Kida; Motokuni Aoki; Seiji Hayashi; Naruya Tomita; Kazuhiro Yamamoto; Atsushi Moriguchi; A Noda; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
Inhibition of growth of human vascular smooth muscle cells by overexpression of p21 gene through induction of apoptosis.
Hypertension 1998;31(1 Pt 2):493-8.
1998: Yoshikage Yo; Ryuichi Morishita; Kazuhiro Yamamoto; Naruya Tomita; Iwao Kida; Seiji Hayashi; Atsushi Moriguchi; S Kato; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Actions of hepatocyte growth factor as a local modulator in the kidney: potential role in pathogenesis of renal disease.
Kidney international 1998;53(1):50-8.
1997: Ryuichi Morishita; Jitsuo Higaki; Seiji Hayashi; Yoshikage Yo; Motokuni Aoki; Shun Nakamura; Atsushi Moriguchi; H Matsushita; Kunihiro Matsumoto; Tadashi Nakamura; Toshio Ogihara
Role of hepatocyte growth factor in endothelial regulation: prevention of high D-glucose-induced endothelial cell death by prostaglandins and phosphodiesterase type 3 inhibitor.
Diabetologia 1997;40(9):1053-61.
1997: M Takagi; T Egawa; T Motomura; J Sakuma-Mochizuki; N Nishimoto; Soji Kasayama; Seiji Hayashi; Masafumi Koga; K Yoshizaki; T Yoshioka; A Okuyama; Tadamitsu Kishimoto
Interleukin-6 secreting phaeochromocytoma associated with clinical markers of inflammation.
Clinical endocrinology 1997;46(4):507-9.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Iwao Kida; Seiji Hayashi; H Matsushita; Yasufumi Kaneda; Toshio Ogihara
In vivo transfer efficiency of antisense oligonucleotides into the myocardium using HVJ-liposome method.
Biochemical and biophysical research communications 1997;231(3):540-5.
1997: Motokuni Aoki; Ryuichi Morishita; Jitsuo Higaki; Atsushi Moriguchi; Seiji Hayashi; H Matsushita; Iwao Kida; Naruya Tomita; Yoshiki Sawa; Yasufumi Kaneda; Toshio Ogihara
Survival of grafts of genetically modified cardiac myocytes transfected with FITC-labeled oligodeoxynucleotides and the beta-galactosidase gene in the noninfarcted area, but not the myocardial infarcted area.
Gene therapy 1997;4(2):120-7.
1997: Ryuichi Morishita; Motokuni Aoki; Shun Nakamura; H Matsushita; Naruya Tomita; Seiji Hayashi; Atsushi Moriguchi; Kunihiro Matsumoto; Tadashi Nakamura; Jitsuo Higaki; Toshio Ogihara
Potential role of a novel vascular modulator, hepatocyte growth factor (HGF), in cardiovascular disease: characterization and regulation of local HGF system.
Journal of atherosclerosis and thrombosis 1997;4(1):12-9.
1996: Seiji Hayashi; Ryuichi Morishita; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; M Nakajima; Yasufumi Kaneda; Jitsuo Higaki; Toshio Ogihara
In vivo transfer of gene and oligodeoxynucleotides into skin of fetal rats by incubation in amniotic fluid.
Gene therapy 1996;3(10):878-85.
1996: Y Nakamura; Ryuichi Morishita; Jitsuo Higaki; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; K Yamada; Seiji Hayashi; Yoshikage Yo; H Nakano; K Matsumoto; Tadashi Nakamura; Toshio Ogihara
Hepatocyte growth factor is a novel member of the endothelium-specific growth factors: additive stimulatory effect of hepatocyte growth factor with basic fibroblast growth factor but not with vascular endothelial growth factor.
Journal of hypertension 1996;14(9):1067-72.
1996: Seiji Hayashi; Ryuichi Morishita; Jitsuo Higaki; Motokuni Aoki; Atsushi Moriguchi; Iwao Kida; S Yoshiki; K Matsumoto; Tadashi Nakamura; Yasufumi Kaneda; Toshio Ogihara
Autocrine-paracrine effects of overexpression of hepatocyte growth factor gene on growth of endothelial cells.
Biochemical and biophysical research communications 1996;220(3):539-45.
1995: Y Nakamura; Ryuichi Morishita; Jitsuo Higaki; Iwao Kida; Motokuni Aoki; Atsushi Moriguchi; K Yamada; Seiji Hayashi; Yoshikage Yo; K Matsumoto
Expression of local hepatocyte growth factor system in vascular tissues.
Biochemical and biophysical research communications 1995;215(2):483-8.
1994: Hisato Tada; Y Irie; A Yagoro; H Ohya; Seiji Hayashi; R Fushimi; H Tamaki; N Amino
Serum concentrations of apolipoproteins in patients with thyroid dysfunction.
Thyroidology / A.P.R.I.M 1994;6(3):93-7.
1994: S Saito; Y Tanio; Isao Tachibana; Seiji Hayashi; Tadamitsu Kishimoto; I Kawase
Complementary DNA sequence encoding the major neural cell adhesion molecule isoform in a human small cell lung cancer cell line.
Lung cancer (Amsterdam, Netherlands) 1994;10(5-6):307-18.
1992: Isao Tachibana; M Watanabe; Y Tanio; Seiji Hayashi; S Hosoe; S Saito; M Matsunashi; Tadashi Osaki; Y Shigedo; T Masuno
Generation of a small cell lung cancer variant resistant to lymphokine-activated killer (LAK) cells: association with resistance to a LAK cell-derived, cytostatic factor.
Cancer research 1992;52(12):3310-6.
1991: S Saito; T Inoue; I Kawase; H Hara; Y Tanio; Isao Tachibana; Seiji Hayashi; M Watanabe; M Matsunashi; Tadashi Osaki
Two monoclonal antibodies against small-cell lung cancer show existence of synergism in binding.
Cancer immunology, immunotherapy : CII 1991;33(3):165-70.
1989: S Hosoe; T Ogura; Seiji Hayashi; K Komuta; T Ikeda; T Shirasaka; I Kawase; T Masuno; S Kishimoto
Induction of tumoricidal macrophages from bone marrow cells of normal mice or mice bearing a colony-stimulating-factor-producing tumor.
Cancer immunology, immunotherapy : CII 1989;28(2):116-22.