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Shunji Hayashidani

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Tetsuya Shiomi; Hiroyuki Tsutsui; Hidenori Matsusaka; Kimiyo Murakami; Shunji Hayashidani; Masaki Ikeuchi; Jing Wen; Toru Kubota; Hideo Utsumi; Akira Takeshita
Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice.
Shunji Hayashidani; Hiroyuki Tsutsui; Tetsuya Shiomi; Masaki Ikeuchi; Hidenori Matsusaka; Nobuhiro Suematsu; Jing Wen; Kensuke Egashira; Akira Takeshita
Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Shunji Hayashidani; Hiroyuki Tsutsui; Masaki Ikeuchi; Tetsuya Shiomi; Hidenori Matsusaka; Toru Kubota; Kyoko Imanaka-Yoshida; Takeshi Itoh; Akira Takeshita
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.

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All Publications

2004: Tetsuya Shiomi; Hiroyuki Tsutsui; Hidenori Matsusaka; Kimiyo Murakami; Shunji Hayashidani; Masaki Ikeuchi; Jing Wen; Toru Kubota; Hideo Utsumi; Akira Takeshita
Overexpression of glutathione peroxidase prevents left ventricular remodeling and failure after myocardial infarction in mice.
Circulation 2004;109(4):544-9.
2003: Shunji Hayashidani; Hiroyuki Tsutsui; Tetsuya Shiomi; Masaki Ikeuchi; Hidenori Matsusaka; Nobuhiro Suematsu; Jing Wen; Kensuke Egashira; Akira Takeshita
Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2003;108(17):2134-40.
2003: Shunji Hayashidani; Hiroyuki Tsutsui; Masaki Ikeuchi; Tetsuya Shiomi; Hidenori Matsusaka; Toru Kubota; Kyoko Imanaka-Yoshida; Takeshi Itoh; Akira Takeshita
Targeted deletion of MMP-2 attenuates early LV rupture and late remodeling after experimental myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1229-35.
2003: Tetsuya Shiomi; Hiroyuki Tsutsui; Masaki Ikeuchi; Hidenori Matsusaka; Shunji Hayashidani; Nobuhiro Suematsu; Jing Wen; Toru Kubota; Akira Takeshita
Streptozotocin-induced hyperglycemia exacerbates left ventricular remodeling and failure after experimental myocardial infarction.
Journal of the American College of Cardiology 2003;42(1):165-72.
2003: Nobuhiro Suematsu; Hiroyuki Tsutsui; Jing Wen; Dongchon Kang; Masaki Ikeuchi; Tomomi Ide; Shunji Hayashidani; Tetsuya Shiomi; Toru Kubota; Naotaka Hamasaki; Akira Takeshita
Oxidative stress mediates tumor necrosis factor-alpha-induced mitochondrial DNA damage and dysfunction in cardiac myocytes.
Circulation 2003;107(10):1418-23.
2002: Tetsuya Shiomi; Hiroyuki Tsutsui; Shunji Hayashidani; Nobuhiro Suematsu; Masaki Ikeuchi; Jing Wen; Minako Ishibashi; Toru Kubota; Kensuke Egashira; Akira Takeshita
Pioglitazone, a peroxisome proliferator-activated receptor-gamma agonist, attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2002;106(24):3126-32.
2002: Ryo Nakamura; Kensuke Egashira; Youji Machida; Shunji Hayashidani; Motohiro Takeya; Hideo Utsumi; Hiroyuki Tsutsui; Akira Takeshita
Probucol attenuates left ventricular dysfunction and remodeling in tachycardia-induced heart failure: roles of oxidative stress and inflammation.
Circulation 2002;106(3):362-7.
2002: Tomomi Ide; Hiroyuki Tsutsui; Noriko Ohashi; Shunji Hayashidani; Nobuhiro Suematsu; Miyuki Tsuchihashi; Hiroshi Tamai; Akira Takeshita
Greater oxidative stress in healthy young men compared with premenopausal women.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(3):438-42.
2002: Shunji Hayashidani; Hiroyuki Tsutsui; Tetsuya Shiomi; Nobuhiro Suematsu; Shintaro Kinugawa; Tomomi Ide; Jing Wen; Akira Takeshita
Fluvastatin, a 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor, attenuates left ventricular remodeling and failure after experimental myocardial infarction.
Circulation 2002;105(7):868-73.
2002: Nobutoshi Kawamura; Hiroyuki Tsutsui; Kae Fukuyama; Shunji Hayashidani; George Koike; Kensuke Egashira; Yasunobu Abe; Hidetaka Yamamoto; Masazumi Tsuneyoshi; Akira Takeshita
Severe pulmonary hypertension in a patient with systemic lupus erythematosus and minimal lupus activity.
Internal medicine (Tokyo, Japan) 2002;41(2):109-12.
2001: Hiroyuki Tsutsui; Tomomi Ide; Tetsuya Shiomi; Dongchon Kang; Shunji Hayashidani; Nobuhiro Suematsu; Jing Wen; Hideo Utsumi; Naotaka Hamasaki; Akira Takeshita
8-oxo-dGTPase, which prevents oxidative stress-induced DNA damage, increases in the mitochondria from failing hearts.
Circulation 2001;104(24):2883-5.
2001: Nobuhiro Suematsu; S Satoh; Shintaro Kinugawa; Hiroyuki Tsutsui; Shunji Hayashidani; Ryo Nakamura; Kensuke Egashira; Naoki Makino; Akira Takeshita
Alpha1-adrenoceptor-Gq-RhoA signaling is upregulated to increase myofibrillar Ca2+ sensitivity in failing hearts.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H637-46.
2001: Hiroyuki Tsutsui; Tomomi Ide; Shunji Hayashidani; Nobuhiro Suematsu; Tetsuya Shiomi; Jing Wen; Kazuhiro Ichikawa; Hideo Utsumi; Akira Takeshita
Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure.
Circulation 2001;104(2):134-6.
2001: Hiroyuki Tsutsui; Tomomi Ide; Shunji Hayashidani; Shintaro Kinugawa; Nobuhiro Suematsu; Hideo Utsumi; Akira Takeshita
Effects of ACE inhibition on left ventricular failure and oxidative stress in Dahl salt-sensitive rats.
Journal of cardiovascular pharmacology 2001;37(6):725-33.
2001: Tomomi Ide; Hiroyuki Tsutsui; Shunji Hayashidani; Dongchon Kang; Nobuhiro Suematsu; K Nakamura; Hideo Utsumi; Naotaka Hamasaki; Akira Takeshita
Mitochondrial DNA damage and dysfunction associated with oxidative stress in failing hearts after myocardial infarction.
Circulation research 2001;88(5):529-35.
2001: Hiroyuki Tsutsui; Shintaro Kinugawa; Tomomi Ide; Shunji Hayashidani; Nobuhiro Suematsu; Shinji Satoh; R Nakamura; Kensuke Egashira; Akira Takeshita
Positive inotropic effects of calcium sensitizers on normal and failing cardiac myocytes.
Journal of cardiovascular pharmacology 2001;37(1):16-24.
2001: Hiroyuki Tsutsui; Tomomi Ide; Shunji Hayashidani; Nobuhiro Suematsu; Hideo Utsumi; R Nakamura; Kensuke Egashira; Akira Takeshita
Greater susceptibility of failing cardiac myocytes to oxygen free radical-mediated injury.
Cardiovascular research 2001;49(1):103-9.
2000: Shintaro Kinugawa; Hiroyuki Tsutsui; Shunji Hayashidani; Tomomi Ide; Nobuhiro Suematsu; S Satoh; Hideo Utsumi; Akira Takeshita
Treatment with dimethylthiourea prevents left ventricular remodeling and failure after experimental myocardial infarction in mice: role of oxidative stress.
Circulation research 2000;87(5):392-8.
2000: Tomomi Ide; Hiroyuki Tsutsui; Shintaro Kinugawa; Nobuhiro Suematsu; Shunji Hayashidani; Kazuhiro Ichikawa; Hideo Utsumi; Yoji Machida; Kensuke Egashira; Akira Takeshita
Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium.
Circulation research 2000;86(2):152-7.