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Frederick Hayden

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Frederick G Hayden
Newer influenza antivirals, biotherapeutics and combinations.
Frederick G Hayden
Experimental human influenza: observations from studies of influenza antivirals.
Kristine M Peterson; Marianne O'Shea; Wiro Stam; Inge C M Mohede; James T Patrie; Frederick G Hayden
Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness.

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All Publications

2013: Frederick G Hayden
Newer influenza antivirals, biotherapeutics and combinations.
Influenza and other respiratory viruses 2013;7 Suppl 1():63-75.
2012: Frederick G Hayden
Experimental human influenza: observations from studies of influenza antivirals.
Antiviral therapy 2012;17(1 Pt B):133-41.
2009: Kristine M Peterson; Marianne O'Shea; Wiro Stam; Inge C M Mohede; James T Patrie; Frederick G Hayden
Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness.
Antiviral therapy 2009;14(1):33-43.
2008: Ann R Falsey; Edward E Walsh; Jose Capellan; Stefan Gravenstein; Maria Zambon; Eddy Yau; Geoffrey J Gorse; Robert Edelman; Frederick G Hayden; Janet E McElhaney; Kathleen M Neuzil; Kristen L Nichol; Eric A F Simões; Peter F Wright; Valérie M-P Sales
Comparison of the safety and immunogenicity of 2 respiratory syncytial virus (rsv) vaccines--nonadjuvanted vaccine or vaccine adjuvanted with alum--given concomitantly with influenza vaccine to high-risk elderly individuals.
The Journal of infectious diseases 2008;198(9):1317-26.
2008: Elizabeth S Higgs; Frederick G Hayden; Tawee Chotpitayasunondh; Jimmy Whitworth; Jeremy Farrar
The Southeast Asian Influenza Clinical Research Network: development and challenges for a new multilateral research endeavor.
Antiviral research 2008;78(1):64-8.
2008: Diane E Pappas; J Owen Hendley; Frederick G Hayden; Birgit Winther
Symptom profile of common colds in school-aged children.
The Pediatric infectious disease journal 2008;27(1):8-11.
2007: Birgit Winther; Frederick G Hayden; J Owen Hendley
Middle ear pressure in preschool age children: influence of respiratory illness, season, and picornavirus or bacteria in the nasopharynx.
Acta oto-laryngologica 2007;127(8):796-800.
2007: John Treanor; Gilbert M Schiff; Frederick G Hayden; Rebecca C Brady; C Mhorag Hay; Anthony L Meyer; Jeanne Holden-Wiltse; Hua Liang; Adam Gilbert; Manon Cox
Safety and immunogenicity of a baculovirus-expressed hemagglutinin influenza vaccine: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2007;297(14):1577-82.
2007: Alison Bermingham; Kelly Henrickson; Frederick G Hayden; Maria Zambon
VII International Symposium on Respiratory Viral Infections.
Antiviral therapy 2007;12(4 Pt B):671-93.
2006: Frederick G Hayden; Andrew T Pavia
Antiviral management of seasonal and pandemic influenza.
The Journal of infectious diseases 2006;194 Suppl 2():S119-26.
2006: Frederick G Hayden
Antivirals for influenza: historical perspectives and lessons learned.
Antiviral research 2006;71(2-3):372-8.
2006: Vasiliy Mishin; Frederick G Hayden; Kathy L Signorelli; Larisa V Gubareva
Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection.
Antiviral research 2006;71(1):64-8.
2006: Arnold S Monto; Jennifer L McKimm-Breschkin; Catherine Macken; Alan W Hampson; Alan Hay; Alexander Klimov; Masato Tashiro; Robert G Webster; Michelle Aymard; Frederick G Hayden; Maria Zambon
Detection of influenza viruses resistant to neuraminidase inhibitors in global surveillance during the first 3 years of their use.
Antimicrobial agents and chemotherapy 2006;50(7):2395-402.
2006: Birgit Winther; Frederick G Hayden; J Owen Hendley
Picornavirus infections in children diagnosed by RT-PCR during longitudinal surveillance with weekly sampling: Association with symptomatic illness and effect of season.
Journal of medical virology 2006;78(5):644-50.
2006: Michael P Malakhov; Laura Aschenbrenner; Donald F Smee; Miles K Wandersee; Robert W Sidwell; Larisa V Gubareva; Vasiliy Mishin; Frederick G Hayden; Do Hyong Kim; Alice Ing; Erin R Campbell; Mang Yu; Fang Fang
Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection.
Antimicrobial agents and chemotherapy 2006;50(4):1470-9.
2006: Frederick G Hayden
Respiratory viral threats.
Current opinion in infectious diseases 2006;19(2):169-78.
2006: Michael G Ison; Vasiliy Mishin; Thomas J Braciale; Frederick G Hayden; Larisa V Gubareva
Comparative activities of oseltamivir and A-322278 in immunocompetent and immunocompromised murine models of influenza virus infection.
The Journal of infectious diseases 2006;193(6):765-72.
2006: Michael G Ison; Larisa V Gubareva; Robert L Atmar; John Treanor; Frederick G Hayden
Recovery of drug-resistant influenza virus from immunocompromised patients: a case series.
The Journal of infectious diseases 2006;193(6):760-4.
2006: Frederick G Hayden
Antiviral resistance in influenza viruses--implications for management and pandemic response.
The New England journal of medicine 2006;354(8):785-8.
2005: Vasiliy Mishin; Frederick G Hayden; Larisa V Gubareva
Susceptibilities of antiviral-resistant influenza viruses to novel neuraminidase inhibitors.
Antimicrobial agents and chemotherapy 2005;49(11):4515-20.
2005: Daniel C Pevear; Frederick G Hayden; Tina M Demenczuk; Linda R Barone; Mark A McKinlay; Marc S Collett
Relationship of pleconaril susceptibility and clinical outcomes in treatment of common colds caused by rhinoviruses.
Antimicrobial agents and chemotherapy 2005;49(11):4492-9.
2005: Vasiliy Mishin; Dmitri V Novikov; Frederick G Hayden; Larisa V Gubareva
Effect of hemagglutinin glycosylation on influenza virus susceptibility to neuraminidase inhibitors.
Journal of virology 2005;79(19):12416-24.
2005: Vasiliy Mishin; Marina S Nedyalkova; Frederick G Hayden; Larisa V Gubareva
Protection afforded by intranasal immunization with the neuraminidase-lacking mutant of influenza A virus in a ferret model.
Vaccine 2005;23(22):2922-7.
2005: J Owen Hendley; Frederick G Hayden; Birgit Winther
Weekly point prevalence of Streptococcus pneumoniae, Hemophilus influenzae and Moraxella catarrhalis in the upper airways of normal young children: effect of respiratory illness and season.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2005;113(3):213-20.
2005: Michael G Ison; Vicky Campbell; Chris Rembold; John Dent; Frederick G Hayden
Cardiac findings during uncomplicated acute influenza in ambulatory adults.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;40(3):415-22.
2005: Luis Barroso; John Treanor; Larisa V Gubareva; Frederick G Hayden
Efficacy and tolerability of the oral neuraminidase inhibitor peramivir in experimental human influenza: randomized, controlled trials for prophylaxis and treatment.
Antiviral therapy 2005;10(8):901-10.
2005: Frederick G Hayden; Alexander Klimov; Masato Tashiro; Alan Hay; Arnold S Monto; Jennifer L McKimm-Breschkin; Catherine Macken; Alan W Hampson; Robert G Webster; Michèle Amyard; Maria Zambon
Neuraminidase inhibitor susceptibility network position statement: antiviral resistance in influenza A/H5N1 viruses.
Antiviral therapy 2005;10(8):873-7.
2004: Frederick G Hayden
Pandemic influenza: is an antiviral response realistic?
The Pediatric infectious disease journal 2004;23(11 Suppl):S262-9.
2004: Cassandra D Salgado; Eve T Giannetta; Frederick G Hayden; Barry M Farr
Preventing nosocomial influenza by improving the vaccine acceptance rate of clinicians.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 2004;25(11):923-8.
2004: Peter W Heymann; Holliday T Carper; Deborah D Murphy; Thomas A E Platts-Mills; James T Patrie; Anne P McLaughlin; Elizabeth A Erwin; Marcus S Shaker; Martha Hellems; Jehanna Peerzada; Frederick G Hayden; Tina K Hatley; Rachel Chamberlain
Viral infections in relation to age, atopy, and season of admission among children hospitalized for wheezing.
The Journal of allergy and clinical immunology 2004;114(2):239-47.
2004: Michael G Ison; Sebastian L Johnston; Peter Openshaw; Brian Murphy; Frederick G Hayden
Current research on respiratory viral infections: Fifth International Symposium.
Antiviral research 2004;62(3):75-110.
2004: Frederick G Hayden; Robert B Belshe; Catalina Villanueva; Riin Lanno; Claire Hughes; Ian Small; Regina Dutkowski; Penelope Ward; Jackie Carr
Management of influenza in households: a prospective, randomized comparison of oseltamivir treatment with or without postexposure prophylaxis.
The Journal of infectious diseases 2004;189(3):440-9.
2004: Frederick G Hayden
Rhinovirus and the lower respiratory tract.
Reviews in medical virology 2004;14(1):17-31.
2003: Frederick G Hayden; Ronald Turner; Jack M Gwaltney; Kathy Chi-Burris; Merril Gersten; Poe-Hirr Hsyu; Amy K Patick; George J Smith; Leora S Zalman
Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers.
Antimicrobial agents and chemotherapy 2003;47(12):3907-16.
2003: David H Chi; J Owen Hendley; Pamela French; Pablo Arango; Frederick G Hayden; Birgit Winther
Nasopharyngeal reservoir of bacterial otitis media and sinusitis pathogens in adults during wellness and viral respiratory illness.
American journal of rhinology 2003;17(4):209-14.
2003: Jennifer L McKimm-Breschkin; T Trivedi; Alan W Hampson; Alan Hay; Alexander Klimov; Masato Tashiro; Frederick G Hayden; Maria Zambon
Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.
Antimicrobial agents and chemotherapy 2003;47(7):2264-72.
2003: Frederick G Hayden; Darrell T Herrington; Teresa L Coats; Kenneth Kim; Ellen C Cooper; Stephen A Villano; Siyu Liu; Spencer Hudson; Daniel C Pevear; Marc S Collett; Mark A McKinlay
Efficacy and safety of oral pleconaril for treatment of colds due to picornaviruses in adults: results of 2 double-blind, randomized, placebo-controlled trials.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(12):1523-32.
2003: Michael G Ison; John W Gnann; Stephanie Nagy-Agren; John Treannor; Carlos Paya; Roy T Steigbigel; Michael Elliott; Heidi L Weiss; Frederick G Hayden
Safety and efficacy of nebulized zanamivir in hospitalized patients with serious influenza.
Antiviral therapy 2003;8(3):183-90.
2003: Juan C Zambrano; Holliday T Carper; Gary P Rakes; James T Patrie; Deborah D Murphy; Thomas A E Platts-Mills; Frederick G Hayden; Jack M Gwaltney; Tina K Hatley; Angela M Owens; Peter W Heymann
Experimental rhinovirus challenges in adults with mild asthma: response to infection in relation to IgE.
The Journal of allergy and clinical immunology 2003;111(5):1008-16.
2003: Michael G Ison; Frederick G Hayden; Laurent Kaiser; Lawrence Corey; Michael Boeckh
Rhinovirus infections in hematopoietic stem cell transplant recipients with pneumonia.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;36(9):1139-43.
2003: N T Wetherall; T Trivedi; J Zeller; Cheryl Hodges-Savola; Jennifer L McKimm-Breschkin; Maria Zambon; Frederick G Hayden
Evaluation of neuraminidase enzyme assays using different substrates to measure susceptibility of influenza virus clinical isolates to neuraminidase inhibitors: report of the neuraminidase inhibitor susceptibility network.
Journal of clinical microbiology 2003;41(2):742-50.
2002: Larisa V Gubareva; Dmitri V Novikov; Frederick G Hayden
Assessment of hemagglutinin sequence heterogeneity during influenza virus transmission in families.
The Journal of infectious diseases 2002;186(11):1575-81.
2002: Larisa V Gubareva; Marina S Nedyalkova; Dmitri V Novikov; K Gopal Murti; Erich Hoffmann; Frederick G Hayden
A release-competent influenza A virus mutant lacking the coding capacity for the neuraminidase active site.
The Journal of general virology 2002;83(Pt 11):2683-92.
2002: Michael G Ison; Frederick G Hayden
Viral infections in immunocompromised patients: what's new with respiratory viruses?
Current opinion in infectious diseases 2002;15(4):355-67.
2002: Michael G Ison; John Mills; Peter Openshaw; Maria Zambon; Albert Osterhaus; Frederick G Hayden
Current research on respiratory viral infections: Fourth International Symposium.
Antiviral research 2002;55(2):227-78.
2002: Birgit Winther; Frederick G Hayden; Eurico Arruda; Regina Dutkowski; Penelope Ward; J Owen Hendley
Viral respiratory infection in schoolchildren: effects on middle ear pressure.
Pediatrics 2002;109(5):826-32.
2002: Warren M Kati; Debra Montgomery; Robert Carrick; Larisa V Gubareva; Clarence J Maring; Keith F McDaniel; Kevin Steffy; Akhteruzzaman Molla; Frederick G Hayden; Dale J Kempf; William Kohlbrenner
In vitro characterization of A-315675, a highly potent inhibitor of A and B strain influenza virus neuraminidases and influenza virus replication.
Antimicrobial agents and chemotherapy 2002;46(4):1014-21.
2002: Frederick G Hayden; Teresa Coats; Kenneth Kim; Howard A Hassman; Mark M Blatter; Bing Zhang; Siyu Liu
Oral pleconaril treatment of picornavirus-associated viral respiratory illness in adults: efficacy and tolerability in phase II clinical trials.
Antiviral therapy 2002;7(1):53-65.
2002: Cassandra D Salgado; Barry M Farr; Keri K Hall; Frederick G Hayden
Influenza in the acute hospital setting.
The Lancet infectious diseases 2002;2(3):145-55.
2002: Marina S Nedyalkova; Frederick G Hayden; Robert G Webster; Larisa V Gubareva
Accumulation of defective neuraminidase (NA) genes by influenza A viruses in the presence of NA inhibitors as a marker of reduced dependence on NA.
The Journal of infectious diseases 2002;185(5):591-8.
2002: Birgit Winther; Eurico Arruda; Theodore J Witek; Steven D Marlin; Michael M Tsianco; Donald J Innes; Frederick G Hayden
Expression of ICAM-1 in nasal epithelium and levels of soluble ICAM-1 in nasal lavage fluid during human experimental rhinovirus infection.
Archives of otolaryngology--head & neck surgery 2002;128(2):131-6.
2002: Larisa V Gubareva; Robert G Webster; Frederick G Hayden
Detection of influenza virus resistance to neuraminidase inhibitors by an enzyme inhibition assay.
Antiviral research 2002;53(1):47-61.
2001: Frederick G Hayden
Perspectives on antiviral use during pandemic influenza.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1416):1877-84.
2001: Larisa V Gubareva; Robert G Webster; Frederick G Hayden
Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants.
Antimicrobial agents and chemotherapy 2001;45(12):3403-8.
2001: Michael G Ison; Frederick G Hayden
Therapeutic options for the management of influenza.
Current opinion in pharmacology 2001;1(5):482-90.
2001: Laurent Kaiser; R S Fritz; S E Straus; Larisa V Gubareva; Frederick G Hayden
Symptom pathogenesis during acute influenza: interleukin-6 and other cytokine responses.
Journal of medical virology 2001;64(3):262-8.
2001: Alexander C Schmidt; Robert B Couch; GJ Galasso; Frederick G Hayden; J Mills; Brian Murphy; Robert M Chanock
Current research on respiratory viral infections: Third International Symposium.
Antiviral research 2001;50(3):157-96.
2001: Elsa K Malcolm; Eurico Arruda; Frederick G Hayden; Laurent Kaiser
Clinical features of patients with acute respiratory illness and rhinovirus in their bronchoalveolar lavages.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2001;21(1):9-16.
2001: Larisa V Gubareva; Laurent Kaiser; M N Matrosovich; Y Soo-Hoo; Frederick G Hayden
Selection of influenza virus mutants in experimentally infected volunteers treated with oseltamivir.
The Journal of infectious diseases 2001;183(4):523-31.
2000: Frederick G Hayden
Influenza virus and rhinovirus-related otitis media: potential for antiviral intervention.
Vaccine 2000;19 Suppl 1():S66-70.
2000: Laurent Kaiser; ON Keene; J M Hammond; Michael Elliott; Frederick G Hayden
Impact of zanamivir on antibiotic use for respiratory events following acute influenza in adolescents and adults.
Archives of internal medicine 2000;160(21):3234-40.
2000: Frederick G Hayden; Larisa V Gubareva; Arnold S Monto; T C Klein; M J Elliot; J M Hammond; S J Sharp; M J Ossi
Inhaled zanamivir for the prevention of influenza in families. Zanamivir Family Study Group.
The New England journal of medicine 2000;343(18):1282-9.
2000: Frederick G Hayden; Lance C Jennings; R Robson; G Schiff; H Jackson; B Rana; G McClelland; D Ipe; N Roberts; Penelope Ward
Oral oseltamivir in human experimental influenza B infection.
Antiviral therapy 2000;5(3):205-13.
2000: Laurent Kaiser; Carolyn Crump; Frederick G Hayden
In vitro activity of pleconaril and AG7088 against selected serotypes and clinical isolates of human rhinoviruses.
Antiviral research 2000;47(3):215-20.
2000: Flor M Munoz; GJ Galasso; J M Gwaltney; Frederick G Hayden; Brian Murphy; R Webster; P Wright; Robert B Couch
Current research on influenza and other respiratory viruses: II international symposium.
Antiviral research 2000;46(2):91-124.
2000: Larisa V Gubareva; Laurent Kaiser; Frederick G Hayden
Influenza virus neuraminidase inhibitors.
Lancet 2000;355(9206):827-35.
2000: Laurent Kaiser; D Henry; N P Flack; ON Keene; Frederick G Hayden
Short-term treatment with zanamivir to prevent influenza: results of a placebo-controlled study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2000;30(3):587-9.
2000: John Treanor; Frederick G Hayden; P S Vrooman; R Barbarash; R Bettis; D Riff; S Singh; N Kinnersley; Penelope Ward; RG Mills
Efficacy and safety of the oral neuraminidase inhibitor oseltamivir in treating acute influenza: a randomized controlled trial. US Oral Neuraminidase Study Group.
JAMA : the journal of the American Medical Association 2000;283(8):1016-24.
1999: Laurent Kaiser; M S Briones; Frederick G Hayden
Performance of virus isolation and Directigen Flu A to detect influenza A virus in experimental human infection.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 1999;14(3):191-7.
1999: Frederick G Hayden; Robert L Atmar; M Schilling; C Johnson; D Poretz; D Paar; L Huson; Penelope Ward; RG Mills
Use of the selective oral neuraminidase inhibitor oseltamivir to prevent influenza.
The New England journal of medicine 1999;341(18):1336-43.
1999: Frederick G Hayden; John Treanor; R S Fritz; M Lobo; Robert F Betts; M Miller; N Kinnersley; RG Mills; Penelope Ward; S E Straus
Use of the oral neuraminidase inhibitor oseltamivir in experimental human influenza: randomized controlled trials for prevention and treatment.
JAMA : the journal of the American Medical Association 1999;282(13):1240-6.
1999: R S Fritz; Frederick G Hayden; David P Calfee; L M Cass; AW Peng; W G Alvord; W Strober; S E Straus
Nasal cytokine and chemokine responses in experimental influenza A virus infection: results of a placebo-controlled trial of intravenous zanamivir treatment.
The Journal of infectious diseases 1999;180(3):586-93.
1999: Laurent Kaiser; Robert B Couch; GJ Galasso; W P Glezen; Robert G Webster; P F Wright; Frederick G Hayden
First International Symposium on Influenza and Other Respiratory Viruses: summary and overview: Kapalua, Maui, Hawaii, December 4-6, 1998.
Antiviral research 1999;42(3):149-75.
1999: David P Calfee; AW Peng; L M Cass; M Lobo; Frederick G Hayden
Safety and efficacy of intravenous zanamivir in preventing experimental human influenza A virus infection.
Antimicrobial agents and chemotherapy 1999;43(7):1616-20.
1999: Ronald Turner; M T Wecker; G Pohl; Theodore J Witek; E McNally; R St George; Birgit Winther; Frederick G Hayden
Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial.
JAMA : the journal of the American Medical Association 1999;281(19):1797-804.
1999: Gary P Rakes; Eurico Arruda; J M Ingram; GE Hoover; J C Zambrano; Frederick G Hayden; Thomas A E Platts-Mills; Peter W Heymann
Rhinovirus and respiratory syncytial virus in wheezing children requiring emergency care. IgE and eosinophil analyses.
American journal of respiratory and critical care medicine 1999;159(3):785-90.
1999: David P Calfee; AW Peng; EK Hussey; M Lobo; Frederick G Hayden
Safety and efficacy of once daily intranasal zanamivir in preventing experimental human influenza A infection.
Antiviral therapy 1999;4(3):143-9.
1999: Frederick G Hayden
Update on influenza and rhinovirus infections.
Advances in experimental medicine and biology 1999;458():55-67.
1999: Laurent Kaiser; Frederick G Hayden
Hospitalizing influenza in adults.
Current clinical topics in infectious diseases 1999;19():112-34.
1998: David P Calfee; Frederick G Hayden
New approaches to influenza chemotherapy. Neuraminidase inhibitors.
Drugs 1998;56(4):537-53.
1998: A Pitkäranta; Jussi Jero; Eurico Arruda; A Virolainen; Frederick G Hayden
Polymerase chain reaction-based detection of rhinovirus, respiratory syncytial virus, and coronavirus in otitis media with effusion.
The Journal of pediatrics 1998;133(3):390-4.
1998: A W Murphy; Thomas A E Platts-Mills; M Lobo; Frederick G Hayden
Respiratory nitric oxide levels in experimental human influenza.
Chest 1998;114(2):452-6.
1998: A Pitkäranta; A Virolainen; Jussi Jero; Eurico Arruda; Frederick G Hayden
Detection of rhinovirus, respiratory syncytial virus, and coronavirus infections in acute otitis media by reverse transcriptase polymerase chain reaction.
Pediatrics 1998;102(2 Pt 1):291-5.
1998: A Pitkäranta; M T Wecker; D C Korts; Frederick G Hayden
Combined intranasal ipratropium bromide and oxymetazoline in experimental rhinovirus infection.
American journal of rhinology 1998;12(2):125-9.
1998: Frederick G Hayden; R Fritz; M C Lobo; W Alvord; W Strober; S E Straus
Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense.
The Journal of clinical investigation 1998;101(3):643-9.
1997: J B Walker; EK Hussey; John Treanor; A Montalvo; Frederick G Hayden
Effects of the neuraminidase inhibitor zanamavir on otologic manifestations of experimental human influenza.
The Journal of infectious diseases 1997;176(6):1417-22.
1997: Eurico Arruda; A Pitkäranta; Theodore J Witek; C A Doyle; Frederick G Hayden
Frequency and natural history of rhinovirus infections in adults during autumn.
Journal of clinical microbiology 1997;35(11):2864-8.
1997: Frederick G Hayden; A D Osterhaus; John Treanor; DM Fleming; Fred Y Aoki; Karl G Nicholson; Arthur Bohnen; H M Hirst; ON Keene; K Wightman
Efficacy and safety of the neuraminidase inhibitor zanamivir in the treatment of influenzavirus infections. GG167 Influenza Study Group.
The New England journal of medicine 1997;337(13):874-80.
1997: Frederick G Hayden
Antivirals for pandemic influenza.
The Journal of infectious diseases 1997;176 Suppl 1():S56-61.
1997: A Pitkäranta; Eurico Arruda; H Malmberg; Frederick G Hayden
Detection of rhinovirus in sinus brushings of patients with acute community-acquired sinusitis by reverse transcription-PCR.
Journal of clinical microbiology 1997;35(7):1791-3.
1997: Frederick G Hayden
Prevention and treatment of influenza in immunocompromised patients.
The American journal of medicine 1997;102(3A):55-60; discussion 75-6.
1997: James C Turner; Frederick G Hayden; M C Lobo; C E Ramirez; D Murren
Epidemiologic evidence for Lancefield group C beta-hemolytic streptococci as a cause of exudative pharyngitis in college students.
Journal of clinical microbiology 1997;35(1):1-4.
1996: K A Adal; R H Flowers; Anne M Anglim; Frederick G Hayden; M G Titus; B J Coyner; Barry M Farr
Prevention of nosocomial influenza.
Infection control and hospital epidemiology : the official journal of the Society of Hospital Epidemiologists of America 1996;17(10):641-8.
1996: Frederick G Hayden; L Diamond; P B Wood; D C Korts; M T Wecker
Effectiveness and safety of intranasal ipratropium bromide in common colds. A randomized, double-blind, placebo-controlled trial.
Annals of internal medicine 1996;125(2):89-97.
1996: Eurico Arruda; Carolyn Crump; B S Rollins; A Ohlin; Frederick G Hayden
Comparative susceptibilities of human embryonic fibroblasts and HeLa cells for isolation of human rhinoviruses.
Journal of clinical microbiology 1996;34(5):1277-9.
1996: L M Gustafson; David Proud; J Owen Hendley; Frederick G Hayden; Jack M Gwaltney
Oral prednisone therapy in experimental rhinovirus infections.
The Journal of allergy and clinical immunology 1996;97(4):1009-14.
1996: William J Doyle; David P Skoner; M White; Frederick G Hayden; A P Kaplan; M A Kaliner; Y Shibayama; Philip Fireman
Pattern of nasal secretions during experimental influenza virus infection.
Rhinology 1996;34(1):2-8.
1996: Frederick G Hayden; John Treanor; R F Betts; M Lobo; J D Esinhart; EK Hussey
Safety and efficacy of the neuraminidase inhibitor GG167 in experimental human influenza.
JAMA : the journal of the American Medical Association 1996;275(4):295-9.
1996: Frederick G Hayden; C A Sable; J D Connor; J Lane
Intravenous ribavirin by constant infusion for serious influenza and parainfluenzavirus infection.
Antiviral therapy 1996;1(1):51-6.
1996: Eurico Arruda; Frederick G Hayden
Update on therapy of influenza and rhinovirus infections.
Advances in experimental medicine and biology 1996;394():175-87.
1996: Frederick G Hayden
Combination antiviral therapy for respiratory virus infections.
Antiviral research 1996;29(1):45-8.
1995: C A Sable; Frederick G Hayden
Orthomyxoviral and paramyxoviral infections in transplant patients.
Infectious disease clinics of North America 1995;9(4):987-1003.
1995: Craig A Buchman; William J Doyle; David P Skoner; J Christopher Post; Cuneyt M Alper; James T Seroky; K Anderson; Robert A Preston; Frederick G Hayden; Philip Fireman
Influenza A virus--induced acute otitis media.
The Journal of infectious diseases 1995;172(5):1348-51.
1995: Eurico Arruda; T R Boyle; Birgit Winther; D C Pevear; Jack M Gwaltney; Frederick G Hayden
Localization of human rhinovirus replication in the upper respiratory tract by in situ hybridization.
The Journal of infectious diseases 1995;171(5):1329-33.
1995: Craig A Buchman; J Douglas Swarts; James T Seroky; N Panagiotou; Frederick G Hayden; William J Doyle
Otologic and systemic manifestations of experimental influenza A virus infection in the ferret.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1995;112(4):572-8.
1995: Frederick G Hayden; G J Hipskind; D H Woerner; G F Eisen; M Janssens; P A Janssen; Koen Andries
Intranasal pirodavir (R77,975) treatment of rhinovirus colds.
Antimicrobial agents and chemotherapy 1995;39(2):290-4.
1994: Frederick G Hayden; B S Rollins; L K Madren
Anti-influenza virus activity of the neuraminidase inhibitor 4-guanidino-Neu5Ac2en in cell culture and in human respiratory epithelium.
Antiviral research 1994;25(2):123-31.
1994: Frederick G Hayden; H N Himel; John P Heggers
Herpesvirus infections in burn patients.
Chest 1994;106(1 Suppl):15S-21S; discussion 34S-35S.
1994: Carolyn Crump; Eurico Arruda; Frederick G Hayden
Comparative antirhinoviral activities of soluble intercellular adhesion molecule-1 (sICAM-1) and chimeric ICAM-1/immunoglobulin A molecule.
Antimicrobial agents and chemotherapy 1994;38(6):1425-7.
1994: Frederick G Hayden; A R Tunkel; John Treanor; R F Betts; S Allerheiligen; J Harris
Oral LY217896 for prevention of experimental influenza A virus infection and illness in humans.
Antimicrobial agents and chemotherapy 1994;38(5):1178-81.
1994: William J Doyle; David P Skoner; Frederick G Hayden; Craig A Buchman; James T Seroky; Philip Fireman
Nasal and otologic effects of experimental influenza A virus infection.
The Annals of otology, rhinology, and laryngology 1994;103(1):59-69.
1994: Eurico Arruda; Carolyn Crump; Frederick G Hayden
In vitro selection of human rhinovirus relatively resistant to soluble intercellular adhesion molecule-1.
Antimicrobial agents and chemotherapy 1994;38(1):66-70.
1993: A L Duff; Elaine S Pomeranz; L E Gelber; G W Price; H Farris; Frederick G Hayden; Thomas A E Platts-Mills; Peter W Heymann
Risk factors for acute wheezing in infants and children: viruses, passive smoke, and IgE antibodies to inhalant allergens.
Pediatrics 1993;92(4):535-40.
1993: Eurico Arruda; Frederick G Hayden
Detection of human rhinovirus RNA in nasal washings by PCR.
Molecular and cellular probes 1993;7(5):373-9.
1993: B S Rollins; A H Elkhatieb; Frederick G Hayden
Comparative anti-influenza virus activity of 2'-deoxy-2'-fluororibosides in vitro.
Antiviral research 1993;21(4):357-68.
1993: William J Doyle; Donald Riker; T P McBride; Frederick G Hayden; J Owen Hendley; J Douglas Swarts; Jack M Gwaltney
Therapeutic effects of an anticholinergic-sympathomimetic combination in induced rhinovirus colds.
The Annals of otology, rhinology, and laryngology 1993;102(7):521-7.
1993: J A Jernigan; B S Lowry; Frederick G Hayden; S A Kyger; Brian P Conway; D H Gröschel; Barry M Farr
Adenovirus type 8 epidemic keratoconjunctivitis in an eye clinic: risk factors and control.
The Journal of infectious diseases 1993;167(6):1307-13.
1993: Ronald Turner; F J Dutko; N H Goldstein; G Lockwood; Frederick G Hayden
Efficacy of oral WIN 54954 for prophylaxis of experimental rhinovirus infection.
Antimicrobial agents and chemotherapy 1993;37(2):297-300.
1992: B W Turner; W S Cail; J Owen Hendley; Frederick G Hayden; William J Doyle; J V Sorrentino; Jack M Gwaltney
Physiologic abnormalities in the paranasal sinuses during experimental rhinovirus colds.
The Journal of allergy and clinical immunology 1992;90(3 Pt 2):474-8.
1992: S J Sperber; William J Doyle; T P McBride; J V Sorrentino; Donald Riker; Frederick G Hayden
Otologic effects of interferon beta serine in experimental rhinovirus colds.
Archives of otolaryngology--head & neck surgery 1992;118(9):933-6.
1992: S J Sperber; J Owen Hendley; Frederick G Hayden; D K Riker; J V Sorrentino; Jack M Gwaltney
Effects of naproxen on experimental rhinovirus colds. A randomized, double-blind, controlled trial.
Annals of internal medicine 1992;117(1):37-41.
1992: Eurico Arruda; Carolyn Crump; S D Marlin; V J Merluzzi; Frederick G Hayden
In vitro studies of the antirhinovirus activity of soluble intercellular adhesion molecule-1.
Antimicrobial agents and chemotherapy 1992;36(6):1186-91.
1992: Frederick G Hayden; Koen Andries; P A Janssen
Safety and efficacy of intranasal pirodavir (R77975) in experimental rhinovirus infection.
Antimicrobial agents and chemotherapy 1992;36(4):727-32.
1992: S J Sperber; B V Smith; Frederick G Hayden
Serologic response and reactogenicity to booster immunization of healthy seropositive adults with live or inactivated varicella vaccine.
Antiviral research 1992;17(3):213-22.
1992: Frederick G Hayden; A J Hay
Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine.
Current topics in microbiology and immunology 1992;176():119-30.
1992: Jack M Gwaltney; O Hendley; Frederick G Hayden; K McIntosh; F B Hollinger; J L Melnick; Ronald Turner
Updated recommendations for safety-testing of viral inocula used in volunteer experiments on rhinovirus colds.
Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progrès en virologie médicale 1992;39():256-63.
1991: Frederick G Hayden; S J Sperber; R B Belshe; R D Clover; A J Hay; S Pyke
Recovery of drug-resistant influenza A virus during therapeutic use of rimantadine.
Antimicrobial agents and chemotherapy 1991;35(9):1741-7.
1991: E de Arruda; T E Mifflin; Jack M Gwaltney; Birgit Winther; Frederick G Hayden
Localization of rhinovirus replication in vitro with in situ hybridization.
Journal of medical virology 1991;34(1):38-44.
1990: Barry M Farr; Jack M Gwaltney; J Owen Hendley; Frederick G Hayden; Robert M Naclerio; T McBride; William J Doyle; J V Sorrentino; D K Riker; David Proud
A randomized controlled trial of glucocorticoid prophylaxis against experimental rhinovirus infection.
The Journal of infectious diseases 1990;162(5):1173-7.
1990: Frederick G Hayden; B S Rollins; A J Hay
Anti-influenza virus activity of the compound LY253963.
Antiviral research 1990;14(1):25-38.
1989: Frederick G Hayden; R B Belshe; R D Clover; A J Hay; M G Oakes; W Soo
Emergence and apparent transmission of rimantadine-resistant influenza A virus in families.
The New England journal of medicine 1989;321(25):1696-702.
1989: S J Sperber; Frederick G Hayden
Protective effect of rhinovirus receptor blocking antibody in human fibroblast cells.
Antiviral research 1989;12(5-6):231-8.
1989: S J Sperber; Paul A Levine; J V Sorrentino; Donald Riker; Frederick G Hayden
Ineffectiveness of recombinant interferon-beta serine nasal drops for prophylaxis of natural colds.
The Journal of infectious diseases 1989;160(4):700-5.
1989: T P McBride; William J Doyle; Frederick G Hayden; Jack M Gwaltney
Alterations of the eustachian tube, middle ear, and nose in rhinovirus infection.
Archives of otolaryngology--head & neck surgery 1989;115(9):1054-9.
1989: S J Sperber; Frederick G Hayden
Comparative susceptibility of respiratory viruses to recombinant interferons-alpha 2b and -beta.
Journal of interferon research 1989;9(3):285-93.
1989: S J Sperber; J V Sorrentino; D K Riker; Frederick G Hayden
Evaluation of an alpha agonist alone and in combination with a nonsteroidal antiinflammatory agent in the treatment of experimental rhinovirus colds.
Bulletin of the New York Academy of Medicine 1989;65(1):145-60.
1988: R L Tominack; R J Wills; L E Gustavson; Frederick G Hayden
Multiple-dose pharmacokinetics of rimantadine in elderly adults.
Antimicrobial agents and chemotherapy 1988;32(12):1813-9.
1988: Frederick G Hayden; D J Innes; S E Mills; Paul A Levine
Intranasal tolerance and histopathologic effects of a novel synthetic interferon, rIFN-alpha Con1.
Antiviral research 1988;10(4-5):225-34.
1988: M J Gaffey; Frederick G Hayden; J C Boyd; Jack M Gwaltney
Ipratropium bromide treatment of experimental rhinovirus infection.
Antimicrobial agents and chemotherapy 1988;32(11):1644-7.
1988: David A Herold; P K Anonick; Michael Kinter; Frederick G Hayden
Measurement of rimantadine in plasma by capillary gas chromatography/mass spectrometry with a deuterium-labeled internal standard.
Clinical chemistry 1988;34(8):1597-9.
1988: Frederick G Hayden; Jack M Gwaltney; R J Colonno
Modification of experimental rhinovirus colds by receptor blockade.
Antiviral research 1988;9(4):233-47.
1988: S J Sperber; Paul A Levine; D J Innes; S E Mills; Frederick G Hayden
Tolerance and efficacy of intranasal administration of recombinant beta serine interferon in healthy adults.
The Journal of infectious diseases 1988;158(1):166-75.
1988: S J Sperber; Frederick G Hayden
Chemotherapy of rhinovirus colds.
Antimicrobial agents and chemotherapy 1988;32(4):409-19.
1988: M J Gaffey; D L Kaiser; Frederick G Hayden
Ineffectiveness of oral terfenadine in natural colds: evidence against histamine as a mediator of common cold symptoms.
The Pediatric infectious disease journal 1988;7(3):223-8.
1988: K E VanLandingham; H B Marsteller; George Ross; Frederick G Hayden
Relapse of herpes simplex encephalitis after conventional acyclovir therapy.
JAMA : the journal of the American Medical Association 1988;259(7):1051-3.
1988: Frederick G Hayden; D L Kaiser; J K Albrecht
Intranasal recombinant alfa-2b interferon treatment of naturally occurring common colds.
Antimicrobial agents and chemotherapy 1988;32(2):224-30.
1987: S J Sperber; Frederick G Hayden
Antiviral chemotherapy and prophylaxis of viral respiratory disease.
Clinics in laboratory medicine 1987;7(4):869-96.
1987: Frederick G Hayden; S E Mills; D J Innes; A Darragh; M Just; S N Linder-Chiccolunghi; L Gauci
Tolerance and nasal histopathologic effects of long-term, low-dose intranasal recombinant interferon alpha-2A (Roferon-A).
Antiviral research 1987;8(3):139-49.
1987: T E Mifflin; J Bowden; M A Lovell; David Bruns; Frederick G Hayden; D H Gröschel; J Savory
Comparison of radioactive (32P and 35S) and biotinylated probes for detection of cytomegalovirus DNA.
Clinical biochemistry 1987;20(4):231-5.
1987: Frederick G Hayden; Birgit Winther; G R Donowitz; S E Mills; D J Innes
Human nasal mucosal responses to topically applied recombinant leukocyte A interferon.
The Journal of infectious diseases 1987;156(1):64-72.
1987: R L Tominack; Frederick G Hayden
Rimantadine hydrochloride and amantadine hydrochloride use in influenza A virus infections.
Infectious disease clinics of North America 1987;1(2):459-78.
1987: Birgit Winther; D J Innes; S E Mills; N Mygind; D Zito; Frederick G Hayden
Lymphocyte subsets in normal airway mucosa of the human nose.
Archives of otolaryngology--head & neck surgery 1987;113(1):59-62.