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Alberto Hayek

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TOP 3
Ivka Afrikanova; Ayse Kayali; Ana Lopez; Alberto Hayek
Is stage-specific embryonic antigen 4 a marker for human ductal stem/progenitor cells?
Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
Generation of functional hair follicles from follicle germs in a nude mouse model of organ replacement regenerative therapy.
Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
Kartogenin: a game-changer in regenerative medicine.

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All Publications

2012: Ivka Afrikanova; Ayse Kayali; Ana Lopez; Alberto Hayek
Is stage-specific embryonic antigen 4 a marker for human ductal stem/progenitor cells?
BioResearch open access 2012;1(4):184-91.
2012: Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
Generation of functional hair follicles from follicle germs in a nude mouse model of organ replacement regenerative therapy.
Regenerative medicine 2012;7(4):475-6.
2012: Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
Kartogenin: a game-changer in regenerative medicine.
Regenerative medicine 2012;7(4):475.
2012: Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
Pumping iron in the brain.
Regenerative medicine 2012;7(4):474.
2012: Alberto Hayek; Amber E Kerstetter-Fogle; Eleftherios Sachlos; Thomas Bollenbach
A new factory for insulin-producing cells: the gut?
Regenerative medicine 2012;7(4):473.
2012: Ayse G Kayali; Ergeng Hao; Alberto Hayek; Andrew Hinton; Ana D Lopez; Charles C King
The SDF-1α/CXCR4 axis is required for proliferation and maturation of human fetal pancreatic endocrine progenitor cells.
PloS one 2012;7(6):e38721.
2010: Thomas J Kaido; Mayra Yebra; Hideaki Kaneto; Vincenzo Cirulli; Alberto Hayek; Anthony M P Montgomery
Impact of integrin-matrix interaction and signaling on insulin gene expression and the mesenchymal transition of human beta-cells.
Journal of cellular physiology 2010;224(1):101-11.
2010: Andrew Hinton; Ivka Afrikanova; Mike Wilson; Charles C King; Brian Maurer; Gene Yeo; Alberto Hayek; Amy E Pasquinelli
A distinct microRNA signature for definitive endoderm derived from human embryonic stem cells.
Stem cells and development 2010;19(6):797-807.
2010: Yue Xu; Xiuwen Zhu; Heung Sik Hahm; Wanguo Wei; Ergeng Hao; Alberto Hayek; Sheng Ding
Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(18):8129-34.
2009: Wenlin Li; HongYan Zhou; Ramzey Abujarour; Saiyong Zhu; Jin Young Joo; Tongxiang Lin; Ergeng Hao; Hans R Schöler; Alberto Hayek; Sheng Ding
Generation of human-induced pluripotent stem cells in the absence of exogenous Sox2.
Stem cells (Dayton, Ohio) 2009;27(12):2992-3000.
2009: Tongxiang Lin; Rajesh Ambasudhan; Xu Yuan; Wenlin Li; Simon Hilcove; Ramzey Abujarour; Xiangyi Lin; Heung Sik Hahm; Ergeng Hao; Alberto Hayek; Sheng Ding
A chemical platform for improved induction of human iPSCs.
Nature methods 2009;6(11):805-8.
2009: Wenlin Li; Wei Wei; Saiyong Zhu; Jinliang Zhu; Yan Shi; Tongxiang Lin; Ergeng Hao; Alberto Hayek; Hongkui Deng; Sheng Ding
Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors.
Cell stem cell 2009;4(1):16-9.
2009: Nathan Bucay; Mayra Yebra; Vincenzo Cirulli; Ivka Afrikanova; Thomas Kaido; Alberto Hayek; Anthony M P Montgomery
A novel approach for the derivation of putative primordial germ cells and sertoli cells from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2009;27(1):68-77.
2008: Charles C King; Gillian M Beattie; Ana D Lopez; Alberto Hayek
Generation of definitive endoderm from human embryonic stem cells cultured in feeder layer-free conditions.
Regenerative medicine 2008;3(2):175-80.
2008: Suparna A Sarkar; Sune Kobberup; R Wong; A D Lopez; N Quayum; T Still; A Kutchma; Jan Jensen; Roberto Gianani; G M Beattie; Jan Jensen; Alberto Hayek; John C Hutton
Global gene expression profiling and histochemical analysis of the developing human fetal pancreas.
Diabetologia 2008;51(2):285-97.
2007: Ayse G Kayali; Luis E Flores; Ana D Lopez; Burak Kutlu; Emmanuel Baetge; Ryuichi Kitamura; Ergeng Hao; Gillian M Beattie; Alberto Hayek
Limited capacity of human adult islets expanded in vitro to redifferentiate into insulin-producing beta-cells.
Diabetes 2007;56(3):703-8.
2006: Shuyuan Yao; Shuibing Chen; julie clark; Ergeng Hao; Gillian M Beattie; Alberto Hayek; Sheng Ding
Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(18):6907-12.
2005: Alberto Hayek
Cell replacement in type 1 diabetes mellitus.
Journal of pediatric endocrinology & metabolism : JPEM 2005;18 Suppl 1():1157-61.
2005: Gillian M Beattie; Ana D Lopez; Nathan Bucay; Andrew Hinton; Meri T Firpo; Charles C King; Alberto Hayek
Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layers.
Stem cells (Dayton, Ohio) 2005;23(4):489-95.
2004: Thomas Kaido; Brandon Perez; Mayra Yebra; Jesse Hill; Vincenzo Cirulli; Alberto Hayek; Anthony M P Montgomery
Alphav-integrin utilization in human beta-cell adhesion, spreading, and motility.
The Journal of biological chemistry 2004;279(17):17731-7.
2004: Alberto Hayek
In search of endocrine progenitor/stem cells in the human pancreas.
Pediatric diabetes 2004;5 Suppl 2():70-4.
2004: Rohan K Humphrey; Gillian M Beattie; Ana D Lopez; Nathan Bucay; Charles C King; Meri T Firpo; Stefan Rose-John; Alberto Hayek
Maintenance of pluripotency in human embryonic stem cells is STAT3 independent.
Stem cells (Dayton, Ohio) 2004;22(4):522-30.
2003: Rohan K Humphrey; Nathan Bucay; Gillian M Beattie; Ana Lopez; Conrad A Messam; Vincenzo Cirulli; Alberto Hayek
Characterization and isolation of promoter-defined nestin-positive cells from the human fetal pancreas.
Diabetes 2003;52(10):2519-25.
2003: Jamileh Movassat; Gillian M Beattie; Ana D Lopez; Bernard Portha; Alberto Hayek
Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells.
Diabetologia 2003;46(6):822-9.
2002: Gillian M Beattie; Anthony M P Montgomery; Ana D Lopez; Ergeng Hao; Brandon Perez; Margaret L Just; Jonathan R T Lakey; Marquis E Hart; Alberto Hayek
A novel approach to increase human islet cell mass while preserving beta-cell function.
Diabetes 2002;51(12):3435-9.
2002: Jamileh Movassat; Gillian M Beattie; Ana D Lopez; Alberto Hayek
Exendin 4 up-regulates expression of PDX 1 and hastens differentiation and maturation of human fetal pancreatic cells.
The Journal of clinical endocrinology and metabolism 2002;87(10):4775-81.
2002: Alberto Hayek; Gillian M Beattie
Alternatives to unmodified human islets for transplantation.
Current diabetes reports 2002;2(4):371-6.
2002: Rohan K Humphrey; Murray S Smith; Bernard E Tuch; Alberto Hayek
Regulation of pancreatic cell differentiation and morphogenesis.
Pediatric diabetes 2002;3(1):46-63.
2000: Carla Demeterco; Gillian M Beattie; S A Dib; Ana D Lopez; Alberto Hayek
A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth.
The Journal of clinical endocrinology and metabolism 2000;85(10):3892-7.
2000: Vincenzo Cirulli; Gillian M Beattie; G Klier; MH Ellisman; Camillo Ricordi; Vito Quaranta; F Frasier; JK Ishii; Alberto Hayek; Daniel R Salomon
Expression and function of alpha(v)beta(3) and alpha(v)beta(5) integrins in the developing pancreas: roles in the adhesion and migration of putative endocrine progenitor cells.
The Journal of cell biology 2000;150(6):1445-60.
2000: TL Halvorsen; G M Beattie; A D Lopez; Alberto Hayek; Fred Levine
Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro.
The Journal of endocrinology 2000;166(1):103-9.
2000: Pamela Itkin-Ansari; Carla Demeterco; S Bossie; D D de la Tour; Gillian M Beattie; Jamileh Movassat; MI Mally; Alberto Hayek; Fred Levine
PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line.
Molecular endocrinology (Baltimore, Md.) 2000;14(6):814-22.
2000: Gillian M Beattie; G Leibowitz; AD Lopez; Fred Levine; Alberto Hayek
Protection from cell death in cultured human fetal pancreatic cells.
Cell transplantation 2000;9(3):431-8.
2000: Gillian M Beattie; Alberto Hayek; Fred Levine
Growth and genetic modification of human beta-cells and beta-cell precursors.
Genetic engineering 2000;22():99-120.
1999: Gillian M Beattie; Pamela Itkin-Ansari; Vincenzo Cirulli; G Leibowitz; AD Lopez; S Bossie; MI Mally; Fred Levine; Alberto Hayek
Sustained proliferation of PDX-1+ cells derived from human islets.
Diabetes 1999;48(5):1013-9.
1999: G Leibowitz; Gillian M Beattie; Tal Kafri; Vincenzo Cirulli; AD Lopez; Alberto Hayek; Fred Levine
Gene transfer to human pancreatic endocrine cells using viral vectors.
Diabetes 1999;48(4):745-53.
1999: G M Beattie; A D Lopez; Timo Otonkoski; Alberto Hayek
Transplantation of human fetal pancreas: fresh vs. cultured fetal islets or ICCS.
Journal of molecular medicine (Berlin, Germany) 1999;77(1):70-3.
1998: Vincenzo Cirulli; Laura Crisa; Gillian M Beattie; MI Mally; AD Lopez; A Fannon; A Ptasznik; Luca Inverardi; Camillo Ricordi; Thomas J Deerinck; MH Ellisman; R A Reisfeld; Alberto Hayek
KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development.
The Journal of cell biology 1998;140(6):1519-34.
1998: Tejal A Desai; W H Chu; J K Tu; G M Beattie; Alberto Hayek; Mauro Ferrari
Microfabricated immunoisolating biocapsules.
Biotechnology and bioengineering 1998;57(1):118-20.
1997: Alberto Hayek; Gillian M Beattie
Experimental transplantation of human fetal and adult pancreatic islets.
The Journal of clinical endocrinology and metabolism 1997;82(8):2471-5.
1997: A Ptasznik; Gillian M Beattie; MI Mally; Vincenzo Cirulli; A Lopez; Alberto Hayek
Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation.
The Journal of cell biology 1997;137(5):1127-36.
1997: S Wang; Gillian M Beattie; MI Mally; AD Lopez; Alberto Hayek; Fred Levine
Analysis of a human fetal pancreatic islet cell line.
Transplantation proceedings 1997;29(4):2219.
1997: Gillian M Beattie; Vincenzo Cirulli; AD Lopez; Alberto Hayek
Ex vivo expansion of human pancreatic endocrine cells.
The Journal of clinical endocrinology and metabolism 1997;82(6):1852-6.
1997: Gillian M Beattie; John H Crowe; AD Lopez; Vincenzo Cirulli; Camillo Ricordi; Alberto Hayek
Trehalose: a cryoprotectant that enhances recovery and preserves function of human pancreatic islets after long-term storage.
Diabetes 1997;46(3):519-23.
1997: G M Beattie; Timo Otonkoski; A D Lopez; Alberto Hayek
Functional beta-cell mass after transplantation of human fetal pancreatic cells: differentiation or proliferation?
Diabetes 1997;46(2):244-8.
1997: Alberto Hayek; G M Beattie
Processing, storage and experimental transplantation of human fetal pancreatic cells.
Annals of transplantation : quarterly of the Polish Transplantation Society 1997;2(3):46-54.
1997: S Wang; Gillian M Beattie; MI Mally; Vincenzo Cirulli; Pamela Itkin-Ansari; AD Lopez; Alberto Hayek; Fred Levine
Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas.
Cell transplantation 1997;6(1):59-67.
1996: S Wang; Gillian M Beattie; Alberto Hayek; Fred Levine
Development of a VSV-G protein pseudotyped retroviral vector system expressing dominant oncogenes from a lacO-modified inducible LTR promoter.
Gene 1996;182(1-2):145-50.
1996: Gillian M Beattie; J S Rubin; MI Mally; Timo Otonkoski; Alberto Hayek
Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact.
Diabetes 1996;45(9):1223-8.
1996: Pamela Itkin-Ansari; Gretchen Bain; Gillian M Beattie; Cornelis Murre; Alberto Hayek; Fred Levine
E2A gene products are not required for insulin gene expression.
Endocrinology 1996;137(8):3540-3.
1996: Timo Otonkoski; Vincenzo Cirulli; M Beattie; MI Mally; G Soto; J S Rubin; Alberto Hayek
A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth.
Endocrinology 1996;137(7):3131-9.
1996: MI Mally; Vincenzo Cirulli; Alberto Hayek; Timo Otonkoski
ICA69 is expressed equally in the human endocrine and exocrine pancreas.
Diabetologia 1996;39(4):474-80.
1996: MI Mally; Vincenzo Cirulli; Timo Otonkoski; G Soto; Alberto Hayek
Ontogeny and tissue distribution of human GAD expression.
Diabetes 1996;45(4):496-501.
1995: Fred Levine; S Wang; Gillian M Beattie; MI Mally; Vincenzo Cirulli; AD Lopez; Alberto Hayek
Development of a cell line from the human fetal pancreas.
Transplantation proceedings 1995;27(6):3410.
1995: Gillian M Beattie; AD Lopez; Alberto Hayek
In vivo maturation and growth potential of human fetal pancreases: fresh versus cultured tissue.
Transplantation proceedings 1995;27(6):3343.
1995: Vincenzo Cirulli; Camillo Ricordi; Alberto Hayek
E-cadherin, NCAM, and EpCAM expression in human fetal pancreata.
Transplantation proceedings 1995;27(6):3335.
1995: Timo Otonkoski; Alberto Hayek
Constitution of a biphasic insulin response to glucose in human fetal pancreatic beta-cells with glucagon-like peptide 1.
The Journal of clinical endocrinology and metabolism 1995;80(12):3779-83.
1995: Alberto Hayek; Gillian M Beattie; Vincenzo Cirulli; AD Lopez; Camillo Ricordi; J S Rubin
Growth factor/matrix-induced proliferation of human adult beta-cells.
Diabetes 1995;44(12):1458-60.
1994: Timo Otonkoski; Gillian M Beattie; AD Lopez; Alberto Hayek
Use of hepatocyte growth factor/scatter factor to increase transplantable human fetal islet cell mass.
Transplantation proceedings 1994;26(6):3334.
1994: G M Beattie; Alberto Hayek
Outcome of human fetal pancreatic transplants according to implantation site.
Transplantation proceedings 1994;26(6):3299.
1994: MI Mally; Timo Otonkoski; AD Lopez; Alberto Hayek
Developmental gene expression in the human fetal pancreas.
Pediatric research 1994;36(4):537-44.
1994: Timo Otonkoski; MI Mally; Alberto Hayek
Opposite effects of beta-cell differentiation and growth on reg expression in human fetal pancreatic cells.
Diabetes 1994;43(9):1164-6.
1994: Gillian M Beattie; C Butler; Alberto Hayek
Morphology and function of cultured human fetal pancreatic cells transplanted into athymic mice: a longitudinal study.
Cell transplantation 1994;3(5):421-5.
1994: Timo Otonkoski; Gillian M Beattie; J S Rubin; AD Lopez; A Baird; Alberto Hayek
Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells.
Diabetes 1994;43(7):947-53.
1994: Fred Levine; Gillian M Beattie; Alberto Hayek
Differential integrin expression facilitates isolation of human fetal pancreatic epithelial cells.
Cell transplantation 1994;3(4):307-13.
1994: Gillian M Beattie; Fred Levine; MI Mally; Timo Otonkoski; J S O'Brien; D R Salomon; Alberto Hayek
Acid beta-galactosidase: a developmentally regulated marker of endocrine cell precursors in the human fetal pancreas.
The Journal of clinical endocrinology and metabolism 1994;78(5):1232-40.
1993: Gillian M Beattie; Timo Otonkoski; AD Lopez; Alberto Hayek
Maturation and function of human fetal pancreatic cells after cryopreservation.
Transplantation 1993;56(6):1340-3.
1993: Timo Otonkoski; Gillian M Beattie; MI Mally; Camillo Ricordi; Alberto Hayek
Nicotinamide is a potent inducer of endocrine differentiation in cultured human fetal pancreatic cells.
The Journal of clinical investigation 1993;92(3):1459-66.
1993: Gillian M Beattie; Alberto Hayek
Islet cell mass and the longevity of islet grafts in diabetic rats.
Cell transplantation 1993;2(2):119-22.
1992: Timo Otonkoski; Gillian M Beattie; AD Lopez; Alberto Hayek
Generation of viable isletlike cell clusters from cryopreserved human fetal pancreas.
Transplantation proceedings 1992;24(6):2832.
1992: Alberto Hayek; Gillian M Beattie
Intrapancreatic islet transplantation in experimental diabetes in the rat.
Metabolism: clinical and experimental 1992;41(12):1367-9.
1992: Alberto Hayek; Gillian M Beattie
Reversal of experimental diabetes by injection of syngeneic islets into peripheral veins.
Cell transplantation 1992;1(1):83-5.
1991: Gillian M Beattie; D A Lappi; A Baird; Alberto Hayek
Functional impact of attachment and purification in the short term culture of human pancreatic islets.
The Journal of clinical endocrinology and metabolism 1991;73(1):93-8.
1991: Alberto Hayek; Gillian M Beattie; AD Lopez; P Chen
The use of digital image processing to quantitate angiogenesis induced by basic fibroblast growth factor and transplanted pancreatic islets.
Microvascular research 1991;41(2):203-9.
1990: Alberto Hayek; AD Lopez; Gillian M Beattie
Angiogenic peptides in pancreatic islet transplantation to diabetic rats.
Transplantation 1990;50(6):931-3.
1990: Gillian M Beattie; D A Lappi; Andrew Baird; Alberto Hayek
Selective elimination of fibroblasts from pancreatic islet monolayers by basic fibroblast growth factor-saporin mitotoxin.
Diabetes 1990;39(8):1002-5.
1990: E Markoff; G M Beattie; Alberto Hayek; U J Lewis
Effects of prolactin and glycosylated prolactin on (pro)insulin synthesis and insulin release from cultured rat pancreatic islets.
Pancreas 1990;5(1):99-103.
1990: Alberto Hayek; AD Lopez; Gillian M Beattie
Factors influencing islet transplantation. Number, location, and metabolic control.
Transplantation 1990;49(1):224-5.
1989: Alberto Hayek; AD Lopez; G M Beattie
Enhancement of pancreatic islet cell monolayer growth by endothelial cell matrix and insulin.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1989;25(2):146-50.
1988: Alberto Hayek; AD Lopez; G M Beattie
Decrease in the number of neonatal islets required for successful transplantation by strict metabolic control of diabetic rats.
Transplantation 1988;45(5):940-2.