Paolo Ascenzi

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Ascenzi Paolo; Marinis Elisabetta De; Masi Alessandra di; Ciaccio Chiara; Coletta Massimo
Peroxynitrite scavenging by ferryl sperm whale myoglobin and human hemoglobin.
Ascenzi Paolo; di Masi Alessandra; Coletta Massimo; Ciaccio Chiara; Fanali Gabriella; Nicoletti Francesco P; Smulevich Giulietta; Fasano Mauro
Ibuprofen impairs allosterically peroxynitrite isomerization by ferric human serum heme-albumin.
di Masi Alessandra; Marinis Elisabetta De; Ascenzi Paolo; Marino Maria
Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects.

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2009: Ascenzi Paolo; Marinis Elisabetta De; Masi Alessandra di; Ciaccio Chiara; Coletta Massimo
Peroxynitrite scavenging by ferryl sperm whale myoglobin and human hemoglobin.
Biochemical and biophysical research communications 2009;390(1):27-31.
2009: Ascenzi Paolo; di Masi Alessandra; Coletta Massimo; Ciaccio Chiara; Fanali Gabriella; Nicoletti Francesco P; Smulevich Giulietta; Fasano Mauro
Ibuprofen impairs allosterically peroxynitrite isomerization by ferric human serum heme-albumin.
The Journal of biological chemistry 2009;284(45):31006-17.
2009: di Masi Alessandra; Marinis Elisabetta De; Ascenzi Paolo; Marino Maria
Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects.
Molecular aspects of medicine 2009;30(5):297-343.
2009: Ascenzi Paolo; di Masi Alessandra; De Sanctis Giampiero; Coletta Massimo; Fasano Mauro
Ibuprofen modulates allosterically NO dissociation from ferrous nitrosylated human serum heme-albumin by binding to three sites.
Biochemical and biophysical research communications 2009;387(1):83-6.
2009: Fundueanu Gheorghe; Constantin Marieta; Ascenzi Paolo
Fast-responsive porous thermoresponsive microspheres for controlled delivery of macromolecules.
International journal of pharmaceutics 2009;379(1):9-17.
2009: Baroni Simona; Pariani Giorgio; Fanali Gabriella; Longo Dario; Ascenzi Paolo; Aime Silvio; Fasano Mauro
Thermodynamic analysis of hydration in human serum heme-albumin.
Biochemical and biophysical research communications 2009;385(3):385-9.
2009: Notari Stefania; Tommasi Chiara; Nicastri Emanuele; Bellagamba Rita; Tempestilli Massimo; Pucillo Leopoldo Paolo; Narciso Pasquale; Ascenzi Paolo
Simultaneous determination of maraviroc and raltegravir in human plasma by HPLC-UV.
IUBMB life 2009;61(4):470-5.
2009: Fanali Gabriella; Pariani Giorgio; Ascenzi Paolo; Fasano Mauro
Allosteric and binding properties of Asp1-Glu382 truncated recombinant human serum albumin--an optical and NMR spectroscopic investigation.
The FEBS journal 2009;276(8):2241-50.
2009: Ascenzi Paolo; De Marinis Elisabetta; Visca Paolo; Ciaccio Chiara; Coletta Massimo
Peroxynitrite detoxification by ferryl Mycobacterium leprae truncated hemoglobin O.
Biochemical and biophysical research communications 2009;380(2):392-6.
2009: Pesce Alessandra; Thijs Liesbet; Nardini Marco; Desmet Filip; Sisinni Lorenza; Gourlay Louise; Bolli Alessandro; Coletta Massimiliano; Van Doorslaer Sabine; Wan Xuehua; Alam Maqsudul; Ascenzi Paolo; Moens Luc; Bolognesi Martino; Dewilde Sylvia
HisE11 and HisF8 provide bis-histidyl heme hexa-coordination in the globin domain of Geobacter sulfurreducens globin-coupled sensor.
Journal of molecular biology 2009;386(1):246-60.
2009: Fanali Gabriella; De Sanctis Giampiero; Gioia Magda; Coletta Massimo; Ascenzi Paolo; Fasano Mauro
Reversible two-step unfolding of heme-human serum albumin: a (1)H-NMR relaxometric and circular dichroism study.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2009;14(2):209-17.
2009: De Marinis Elisabetta; Casella Luigi; Ciaccio Chiara; Coletta Massimo; Visca Paolo; Ascenzi Paolo
Catalytic peroxidation of nitrogen monoxide and peroxynitrite by globins.
IUBMB life 2009;61(1):62-73.
2009: Fundueanu Gheorghe; Constantin Marieta; Ascenzi Paolo
Poly(N-isopropylacrylamide-co-acrylamide) cross-linked thermoresponsive microspheres obtained from preformed polymers: Influence of the physico-chemical characteristics of drugs on their release profiles.
Acta biomaterialia 2009;5(1):363-73.
2008: Colantonio Patrizia; Leboffe Loris; Bolli Alessandro; Marino Maria; Ascenzi Paolo; Luisi Grazia
Human caspase-3 inhibition by Z-tLeu-Asp-H: tLeu(P2) counterbalances Asp(P4) and Glu(P3) specific inhibitor truncation.
Biochemical and biophysical research communications 2008;377(3):757-62.
2008: Bolli Alessandro; Galluzzo Paola; Ascenzi Paolo; Del Pozzo Giovanna; Manco Immacolata; Vietri Maria Teresa; Mita Luigi; Altucci Lucia; Mita Damiano Gustavo; Marino Maria
Laccase treatment impairs bisphenol A-induced cancer cell proliferation affecting estrogen receptor alpha-dependent rapid signals.
IUBMB life 2008;60(12):843-52.
2008: Polticelli F; Bocedi A; Minervini G; Ascenzi P
Human haptoglobin structure and function--a molecular modelling study.
The FEBS journal 2008;275(22):5648-56.
2008: Marino Maria; Ascenzi Paolo
Membrane association of estrogen receptor alpha and beta influences 17beta-estradiol-mediated cancer cell proliferation.
Steroids 2008;73(9-10):853-8.
2008: Imperi Francesco; Putignani Lorenza; Tiburzi Federica; Ambrosi Cecilia; Cipollone Rita; Ascenzi Paolo; Visca Paolo
Membrane-association determinants of the omega-amino acid monooxygenase PvdA, a pyoverdine biosynthetic enzyme from Pseudomonas aeruginosa.
Microbiology (Reading, England) 2008;154(Pt 9):2804-13.
2008: Nicoletti Francesco P; Howes Barry D; Fittipaldi Maria; Fanali Gabriella; Fasano Mauro; Ascenzi Paolo; Smulevich Giulietta
Ibuprofen induces an allosteric conformational transition in the heme complex of human serum albumin with significant effects on heme ligation.
Journal of the American Chemical Society 2008;130(35):11677-88.
2008: Ascenzi Paolo; De Marinis Elisabetta; Coletta Massimo; Visca Paolo
H2O2 and (.)NO scavenging by Mycobacterium leprae truncated hemoglobin O.
Biochemical and biophysical research communications 2008;373(2):197-201.
2008: Fundueanu Gheorghe; Constantin Marieta; Ascenzi Paolo
Preparation and characterization of pH- and temperature-sensitive pullulan microspheres for controlled release of drugs.
Biomaterials 2008;29(18):2767-75.
2008: Ascenzi Paolo; Bocedi Alessio; Heptonstall Julia; Capobianchi Maria Rosaria; Di Caro Antonino; Mastrangelo Eloise; Bolognesi Martino; Ippolito Giuseppe
Ebolavirus and Marburgvirus: insight the Filoviridae family.
Molecular aspects of medicine 2008;29(3):151-85.
2008: di Masi Alessandra; Viganotti Mara; Polticelli Fabio; Ascenzi Paolo; Tanzarella Caterina; Antoccia Antonio
The R215W mutation in NBS1 impairs gamma-H2AX binding and affects DNA repair: molecular bases for the severe phenotype of 657del5/R215W Nijmegen breakage syndrome patients.
Biochemical and biophysical research communications 2008;369(3):835-40.
2008: Ascenzi Paolo; Imperi Francesco; Coletta Massimo; Fasano Mauro
Abacavir and warfarin modulate allosterically kinetics of NO dissociation from ferrous nitrosylated human serum heme-albumin.
Biochemical and biophysical research communications 2008;369(2):686-91.
2008: Galluzzo Paola; Ascenzi Paolo; Bulzomi Pamela; Marino Maria
The nutritional flavanone naringenin triggers antiestrogenic effects by regulating estrogen receptor alpha-palmitoylation.
Endocrinology 2008;149(5):2567-75.
2008: Notari Stefania; Mancone Carmine; Alonzi Tonino; Tripodi Marco; Narciso Pasquale; Ascenzi Paolo
Determination of abacavir, amprenavir, didanosine, efavirenz, nevirapine, and stavudine concentration in human plasma by MALDI-TOF/TOF.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2008;863(2):249-57.
2008: Romeo Cristina; Di Francesco Laura; Oliverio Marco; Palazzo Paola; Massilia Gabriella Raybaudi; Ascenzi Paolo; Polticelli Fabio; Schininà Maria Eugenia
Conus ventricosus venom peptides profiling by HPLC-MS: a new insight in the intraspecific variation.
Journal of separation science 2008;31(3):488-98.
2008: Bolli Alessandro; Ciaccio Chiara; Coletta Massimo; Nardini Marco; Bolognesi Martino; Pesce Alessandra; Guertin Michel; Visca Paolo; Ascenzi Paolo
Ferrous Campylobacter jejuni truncated hemoglobin P displays an extremely high reactivity for cyanide - a comparative study.
The FEBS journal 2008;275(4):633-45.
2008: Nardini Marco; Pesce Alessandra; Thijs Liesbet; Saito Jennifer A; Dewilde Sylvia; Alam Maqsudul; Ascenzi Paolo; Coletta Massimiliano; Ciaccio Chiara; Moens Luc; Bolognesi Martino
Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity.
EMBO reports 2008;9(2):157-63.
2008: Tommasi Chiara; Nicastri Emanuele; Corpolongo Angela; Ivanovic Jelena; Notari Stefania; Ascenzi Paolo; Andreoni Massimo; Narciso Pasquale
Stopping antiretroviral therapy: role for therapeutic drug monitoring.
AIDS (London, England) 2008;22(2):315-6.
2008: Aureli Loretta; Gioia Magda; Cerbara Ilaria; Monaco Susanna; Fasciglione Giovanni Francesco; Marini Stefano; Ascenzi Paolo; Topai Alessandra; Coletta Massimo
Structural bases for substrate and inhibitor recognition by matrix metalloproteinases.
Current medicinal chemistry 2008;15(22):2192-222.
2008: Cipollone Rita; Ascenzi Paolo; Tomao Paola; Imperi Francesco; Visca Paolo
Enzymatic detoxification of cyanide: clues from Pseudomonas aeruginosa Rhodanese.
Journal of molecular microbiology and biotechnology 2008;15(2-3):199-211.
2008: Ascenzi Paolo; Visca Paolo
Scavenging of reactive nitrogen species by mycobacterial truncated hemoglobins.
Methods in enzymology 2008;436():317-37.
2007: Thijs Liesbet; Vinck Evi; Bolli Alessandro; Trandafir Florin; Wan Xuehua; Hoogewijs David; Coletta Massimiliano; Fago Angela; Weber Roy E; Van Doorslaer Sabine; Ascenzi Paolo; Alam Maqsudul; Moens Luc; Dewilde Sylvia
Characterization of a globin-coupled oxygen sensor with a gene-regulating function.
The Journal of biological chemistry 2007;282(52):37325-40.
2007: Ascenzi Paolo; Fasano Mauro
Heme-hemopexin: a 'chronosteric' heme-protein.
IUBMB life 2007;59(11):700-8.
2007: Ascenzi Paolo; Ciaccio Chiara; Coletta Massimo
Peroxynitrite-mediated oxidation of ferrous carbonylated myoglobin is limited by carbon monoxide dissociation.
Biochemical and biophysical research communications 2007;363(4):931-6.
2007: Nicolis Stefania; Monzani Enrico; Ciaccio Chiara; Ascenzi Paolo; Moens Luc; Casella Luigi
Reactivity and endogenous modification by nitrite and hydrogen peroxide: does human neuroglobin act only as a scavenger?
The Biochemical journal 2007;407(1):89-99.
2007: Fanali Gabriella; Bocedi Alessio; Ascenzi Paolo; Fasano Mauro
Modulation of heme and myristate binding to human serum albumin by anti-HIV drugs. An optical and NMR spectroscopic study.
The FEBS journal 2007;274(17):4491-502.
2007: Ascenzi Paolo; Bellelli Andrea; Coletta Massimo; Colosimo Alfredo; Falcioni Giancarlo; Giacometti Giorgio M; Ippoliti Rodolfo; Zolla Lello; Giardina Bruno
Multiple strategies for O2 transport: from simplicity to complexity.
IUBMB life 2007;59(8-9):600-16.
2007: Ascenzi Paolo; Petrella Giovanni; Coletta Massimo
Ferricyanide-mediated oxidation of ferrous nitrosylated sperm whale myoglobin involves the formation of the ferric nitrosylated intermediate.
Biochemical and biophysical research communications 2007;359(4):871-6.
2007: Ascenzi Paolo; Bolognesi Martino; Milani Mario; Guertin Michel; Visca Paolo
Mycobacterial truncated hemoglobins: from genes to functions.
Gene 2007;398(1-2):42-51.
2007: Fanali Gabriella; Ascenzi Paolo; Fasano Mauro
Effect of prototypic drugs ibuprofen and warfarin on global chaotropic unfolding of human serum heme-albumin: a fast-field-cycling 1H-NMR relaxometric study.
Biophysical chemistry 2007;129(1):29-35.
2007: Fasano Mauro; Fanali Gabriella; Leboffe Loris; Ascenzi Paolo
Heme binding to albuminoid proteins is the result of recent evolution.
IUBMB life 2007;59(7):436-40.
2007: Ascenzi Paolo; Bolognesi Martino; Visca Paolo
*NO dissociation represents the rate limiting step for O2-mediated oxidation of ferrous nitrosylated Mycobacterium leprae truncated hemoglobin O.
Biochemical and biophysical research communications 2007;357(3):809-14.
2007: Fundueanu Gheorghe; Constantin Marieta; Bortolotti Fabrizio; Cortesi Rita; Ascenzi Paolo; Menegatti Enea
Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;66(1):11-20.
2007: Cipollone Rita; Ascenzi Paolo; Visca Paolo
Common themes and variations in the rhodanese superfamily.
IUBMB life 2007;59(2):51-9.
2007: Ascenzi Paolo; Fasano Mauro
Abacavir modulates peroxynitrite-mediated oxidation of ferrous nitrosylated human serum heme-albumin.
Biochemical and biophysical research communications 2007;353(2):469-74.
2007: Constantin M; Fundueanu G; Bortolotti F; Cortesi R; Ascenzi P; Menegatti E
A novel multicompartimental system based on aminated poly(vinyl alcohol) microspheres/succinoylated pullulan microspheres for oral delivery of anionic drugs.
International journal of pharmaceutics 2007;330(1-2):129-37.
2007: Ascenzi Paolo; Bocedi Alessio; Antonini Giovanni; Bolognesi Martino; Fasano Mauro
Reductive nitrosylation and peroxynitrite-mediated oxidation of heme-hemopexin.
The FEBS journal 2007;274(2):551-62.
2007: Cipollone Rita; Frangipani Emanuela; Tiburzi Federica; Imperi Francesco; Ascenzi Paolo; Visca Paolo
Involvement of Pseudomonas aeruginosa rhodanese in protection from cyanide toxicity.
Applied and environmental microbiology 2007;73(2):390-8.
2006: Marino Maria; Ascenzi Paolo
Steroid hormone rapid signaling: the pivotal role of S-palmitoylation.
IUBMB life 2006;58(12):716-9.
2006: Ascenzi Paolo; Milani Mario; Visca Paolo
Peroxynitrite scavenging by ferrous truncated hemoglobin GlbO from Mycobacterium leprae.
Biochemical and biophysical research communications 2006;351(2):528-33.
2006: Nardini Marco; Pesce Alessandra; Labarre Marie; Richard Christian; Bolli Alessandro; Ascenzi Paolo; Guertin Michel; Bolognesi Martino
Structural determinants in the group III truncated hemoglobin from Campylobacter jejuni.
The Journal of biological chemistry 2006;281(49):37803-12.
2006: Marino Maria; Galluzzo Paola; Ascenzi Paolo
Estrogen signaling multiple pathways to impact gene transcription.
Current genomics 2006;7(8):497-508.
2006: Ascenzi Paolo; Bocedi Alessio; Visca Paolo; Minetti Maurizio; Clementi Emilio
Does CO(2) modulate peroxynitrite specificity?
IUBMB life 2006;58(10):611-3.
2006: Ascenzi Paolo; Marino Maria; Menegatti Enea
CO2 impairs peroxynitrite-mediated inhibition of human caspase-3.
Biochemical and biophysical research communications 2006;349(1):367-71.
2006: Ascenzi Paolo; Bocedi Alessio; Marino Maria
Structure-function relationship of estrogen receptor alpha and beta: impact on human health.
Molecular aspects of medicine 2006;27(4):299-402.
2006: de Sanctis Daniele; Ascenzi Paolo; Bocedi Alessio; Dewilde Sylvia; Burmester Thorsten; Hankeln Thomas; Moens Luc; Bolognesi Martino
Cyanide binding and heme cavity conformational transitions in Drosophila melanogaster hexacoordinate hemoglobin.
Biochemistry 2006;45(33):10054-61.
2006: Bianchini Gianluca; Bocedi Alessio; Ascenzi Paolo; Gavuzzo Enrico; Mazza Fernando; Aschi Massimiliano
Molecular dynamics simulation of Leishmania major surface metalloprotease GP63 (leishmanolysin).
Proteins 2006;64(2):385-90.
2006: Marino M; Galluzzo P; Leone S; Acconcia F; Ascenzi P
Nitric oxide impairs the 17beta-estradiol-induced apoptosis in human colon adenocarcinoma cells.
Endocrine-related cancer 2006;13(2):559-69.
2006: Fasano Mauro; Antonini Giovanni; Ascenzi Paolo
O2-mediated oxidation of hemopexin-heme(II)-NO.
Biochemical and biophysical research communications 2006;345(2):704-12.
2006: Fabozzi Giulia; Ascenzi Paolo; Renzi Simona Di; Visca Paolo
Truncated hemoglobin GlbO from Mycobacterium leprae alleviates nitric oxide toxicity.
Microbial pathogenesis 2006;40(5):211-20.
2006: Cipollone Rita; Ascenzi Paolo; Frangipani Emanuela; Visca Paolo
Cyanide detoxification by recombinant bacterial rhodanese.
Chemosphere 2006;63(6):942-9.
2006: Ascenzi Paolo; Bocedi Alessio; Notari Stefania; Fanali Gabriella; Fesce Riccardo; Fasano Mauro
Allosteric modulation of drug binding to human serum albumin.
Mini reviews in medicinal chemistry 2006;6(4):483-9.
2006: Marino Maria; Ascenzi Paolo; Acconcia Filippo
S-palmitoylation modulates estrogen receptor alpha localization and functions.
Steroids 2006;71(4):298-303.
2006: Bianchi Marzia; Polticelli Fabio; Ascenzi Paolo; Botta Maurizio; Federico Rodolfo; Mariottini Paolo; Cona Alessandra
Inhibition of polyamine and spermine oxidases by polyamine analogues.
The FEBS journal 2006;273(6):1115-23.
2006: Notari Stefania; Mancone Carmine; Tripodi Marco; Narciso Pasquale; Fasano Mauro; Ascenzi Paolo
Determination of anti-HIV drug concentration in human plasma by MALDI-TOF/TOF.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;833(1):109-16.
2006: Notari Stefania; Bocedi Alessio; Ippolito Giuseppe; Narciso Pasquale; Pucillo Leopoldo Paolo; Tossini Gianna; Donnorso Raffaele Perrone; Gasparrini Francesco; Ascenzi Paolo
Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2006;831(1-2):258-66.
2006: Ascenzi Paolo; Bocedi Alessio; Bolognesi Martino; Fabozzi Giulia; Milani Mario; Visca Paolo
Nitric oxide scavenging by Mycobacterium leprae GlbO involves the formation of the ferric heme-bound peroxynitrite intermediate.
Biochemical and biophysical research communications 2006;339(1):450-6.
2005: Marino Maria; Ascenzi Paolo
Do steroid hormones function via multiple signaling pathways?
IUBMB life 2005;57(12):825-7.
2005: Fasano Mauro; Curry Stephen; Terreno Enzo; Galliano Monica; Fanali Gabriella; Narciso Pasquale; Notari Stefania; Ascenzi Paolo
The extraordinary ligand binding properties of human serum albumin.
IUBMB life 2005;57(12):787-96.
2005: Bocedi Alessio; Notari Stefania; Menegatti Enea; Fanali Gabriella; Fasano Mauro; Ascenzi Paolo
Allosteric modulation of anti-HIV drug and ferric heme binding to human serum albumin.
The FEBS journal 2005;272(24):6287-96.
2005: Pesce Alessandra; Nardini Marco; Dewilde Sylvia; Hoogewijs David; Ascenzi Paolo; Moens Luc; Bolognesi Martino
Modulation of oxygen binding to insect hemoglobins: the structure of hemoglobin from the botfly Gasterophilus intestinalis.
Protein science : a publication of the Protein Society 2005;14(12):3057-63.
2005: Ascenzi Paolo; Bocedi Alessio; Visca Paolo; Altruda Fiorella; Tolosano Emanuela; Beringhelli Tiziana; Fasano Mauro
Hemoglobin and heme scavenging.
IUBMB life 2005;57(11):749-59.
2005: Ascenzi Paolo; Bocedi Alessio; Gradoni Luigi
Do neuroglobin and myoglobin protect Toxoplasma gondii from nitrosative stress?
IUBMB life 2005;57(10):689-91.
2005: Fundueanu Gheorghe; Constantin Marieta; Bortolotti Fabrizio; Ascenzi Paolo; Cortesi Rita; Menegatti Enea
Preparation and characterisation of thermoresponsive poly[(N-isopropylacrylamide-co-acrylamide-co-(hydroxyethyl acrylate)] microspheres as a matrix for the pulsed release of drugs.
Macromolecular bioscience 2005;5(10):955-64.
2005: Marino Maria; Acconcia Filippo; Ascenzi Paolo
Estrogen receptor signalling: bases for drug actions.
Current drug targets. Immune, endocrine and metabolic disorders 2005;5(3):305-14.
2005: Fanali Gabriella; Fesce Riccardo; Agrati Cristina; Ascenzi Paolo; Fasano Mauro
Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin. Optical and NMR spectroscopy characterization.
The FEBS journal 2005;272(18):4672-83.
2005: Milani Mario; Leoni Livia; Rampioni Giordano; Zennaro Elisabetta; Ascenzi Paolo; Bolognesi Martino
An active-like structure in the unphosphorylated StyR response regulator suggests a phosphorylation- dependent allosteric activation mechanism.
Structure (London, England : 1993) 2005;13(9):1289-97.
2005: Ascenzi Paolo
How I became a biochemist.
IUBMB life 2005;57(8):599-601.
2005: Ascenzi Paolo; Bocedi Alessio; Notari Stefania; Menegatti Enea; Fasano Mauro
Heme impairs allosterically drug binding to human serum albumin Sudlow's site I.
Biochemical and biophysical research communications 2005;334(2):481-6.
2005: Ascenzi Paolo; Gallina Carlo; Bolognesi Martino
Thrombin inhibition by the highly selective 'reversible suicide substrate' N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p-nitrophenyl ester.
Protein and peptide letters 2005;12(5):433-8.
2005: de Sanctis Daniele; Dewilde Sylvia; Vonrhein Clemens; Pesce Alessandra; Moens Luc; Ascenzi Paolo; Hankeln Thomas; Burmester Thorsten; Ponassi Marco; Nardini Marco; Bolognesi Martino
Bishistidyl heme hexacoordination, a key structural property in Drosophila melanogaster hemoglobin.
The Journal of biological chemistry 2005;280(29):27222-9.
2005: Ascenzi Paolo; Bocedi Alessio; Fasano Mauro; Gioia Magda; Marini Stefano; Coletta Massimo
Proton-linked subunit heterogeneity in ferrous nitrosylated human adult hemoglobin: an EPR study.
Journal of inorganic biochemistry 2005;99(5):1255-9.
2005: Polticelli Fabio; Zaini Germano; Bolli Alessandro; Antonini Giovanni; Gradoni Luigi; Ascenzi Paolo
Probing the cruzain S2 recognition subsite: a kinetic and binding energy calculation study.
Biochemistry 2005;44(8):2781-9.
2005: Fabozzi Giulia; Modiano Guido; Poccia Fabrizio; Visca Paolo; Ascenzi Paolo
Is there an answer? Is there a genetic basis for human susceptibility to leprosy?
IUBMB life 2005;57(2):119-21.
2005: Milani Mario; Pesce Alessandra; Nardini Marco; Ouellet Hugues; Ouellet Yannick; Dewilde Sylvia; Bocedi Alessio; Ascenzi Paolo; Guertin Michel; Moens Luc; Friedman Joel M; Wittenberg Jonathan B; Bolognesi Martino
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins.
Journal of inorganic biochemistry 2005;99(1):97-109.
2005: Acconcia Filippo; Ascenzi Paolo; Bocedi Alessio; Spisni Enzo; Tomasi Vittorio; Trentalance Anna; Visca Paolo; Marino Maria
Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol.
Molecular biology of the cell 2005;16(1):231-7.
2004: Ascenzi Paolo; Bocedi Alessio; Gentile Marco; Visca Paolo; Gradoni Luigi
Inactivation of parasite cysteine proteinases by the NO-donor 4-(phenylsulfonyl)-3-((2-(dimethylamino)ethyl)thio)-furoxan oxalate.
Biochimica et biophysica acta 2004;1703(1):69-77.
2004: Cipollone Rita; Bigotti Maria Giulia; Frangipani Emanuela; Ascenzi Paolo; Visca Paolo
Characterization of a rhodanese from the cyanogenic bacterium Pseudomonas aeruginosa.
Biochemical and biophysical research communications 2004;325(1):85-90.
2004: de Sanctis Daniele; Pesce Alessandra; Nardini Marco; Bolognesi Martino; Bocedi Alessio; Ascenzi Paolo
Structure-function relationships in the growing hexa-coordinate hemoglobin sub-family.
IUBMB life 2004;56(11-12):643-51.
2004: Pesce Alessandra; De Sanctis Daniele; Nardini Marco; Dewilde Sylvia; Moens Luc; Hankeln Thomas; Burmester Thorsten; Ascenzi Paolo; Bolognesi Martino
Reversible hexa- to penta-coordination of the heme Fe atom modulates ligand binding properties of neuroglobin and cytoglobin.
IUBMB life 2004;56(11-12):657-64.
2004: Constantin Marieta; Fundueanu Gheorghe; Bortolotti Fabrizio; Cortesi Rita; Ascenzi Paolo; Menegatti Enea
Preparation and characterisation of poly(vinyl alcohol)/cyclodextrin microspheres as matrix for inclusion and separation of drugs.
International journal of pharmaceutics 2004;285(1-2):87-96.
2004: Bocedi Alessio; Notaril Stefania; Narciso Pasquale; Bolli Alessandro; Fasano Mauro; Ascenzi Paolo
Binding of anti-HIV drugs to human serum albumin.
IUBMB life 2004;56(10):609-14.
2004: Fasano Mauro; Bocedi Alessio; Mattu Marco; Coletta Massimo; Ascenzi Paolo
Nitrosylation of rabbit ferrous heme-hemopexin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2004;9(7):800-6.
2004: Fasano Mauro; Fanali Gabriella; Polticelli Fabio; Ascenzi Paolo; Antonini Giovanni
1H NMR relaxometric characterization of bovine lactoferrin.
Journal of inorganic biochemistry 2004;98(8):1421-6.
2004: Pesce Alessandra; Nardini Marco; Ascenzi Paolo; Geuens Eva; Dewilde Sylvia; Moens Luc; Bolognesi Martino; Riggs Austen F; Hale Angela; Deng Pengchi; Nienhaus G Ulrich; Olson John S; Nienhaus Karin
Thr-E11 regulates O2 affinity in Cerebratulus lacteus mini-hemoglobin.
The Journal of biological chemistry 2004;279(32):33662-72.
2004: Ascenzi Paolo; Bocedi Alessio; Leoni Livia; Visca Paolo; Zennaro Elisabetta; Milani Mario; Bolognesi Martino
CO sniffing through heme-based sensor proteins.
IUBMB life 2004;56(6):309-15.
2004: Gradoni L; Ascenzi P
[Nitric oxide and anti-protozoan chemotherapy]
Parassitologia 2004;46(1-2):101-3.
2004: Massucci Maria Teresa; Giansanti Francesco; Di Nino Giovanna; Turacchio Manola; Giardi Maria Federica; Botti Dario; Ippoliti Rodolfo; De Giulio Beatrice; Siciliano Rosa Anna; Donnarumma Giovanna; Valenti Piera; Bocedi Alessio; Polticelli Fabio; Ascenzi Paolo; Antonini Giovanni
Proteolytic activity of bovine lactoferrin.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 2004;17(3):249-55.
2004: Eliseo Tommaso; Cicero Daniel Oscar; Romeo Cristina; Schininà Maria Eugenia; Massilia Gabriella Raybaudi; Polticelli Fabio; Ascenzi Paolo; Paci Maurizio
Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator.
Biopolymers 2004;74(3):189-98.
2004: Milani Mario; Ouellet Yannick; Ouellet Hugues; Guertin Michel; Boffi Alberto; Antonini Giovanni; Bocedi Alessio; Mattu Marco; Bolognesi Martino; Ascenzi Paolo
Cyanide binding to truncated hemoglobins: a crystallographic and kinetic study.
Biochemistry 2004;43(18):5213-21.
2004: Milani Mario; Pesce Alessandra; Ouellet Yannick; Dewilde Sylvia; Friedman Joel; Ascenzi Paolo; Guertin Michel; Bolognesi Martino
Heme-ligand tunneling in group I truncated hemoglobins.
The Journal of biological chemistry 2004;279(20):21520-5.
2004: de Sanctis Daniele; Dewilde Sylvia; Pesce Alessandra; Moens Luc; Ascenzi Paolo; Hankeln Thomas; Burmester Thorsten; Bolognesi Martino
Mapping protein matrix cavities in human cytoglobin through Xe atom binding.
Biochemical and biophysical research communications 2004;316(4):1217-21.
2004: Acconcia Filippo; Ascenzi Paolo; Fabozzi Giulia; Visca Paolo; Marino Maria
S-palmitoylation modulates human estrogen receptor-alpha functions.
Biochemical and biophysical research communications 2004;316(3):878-83.
2004: Bocedi Alessio; Gradoni Luigi; Menegatti Enea; Ascenzi Paolo
Kinetics of parasite cysteine proteinase inactivation by NO-donors.
Biochemical and biophysical research communications 2004;315(3):710-8.
2004: de Sanctis Daniele; Dewilde Sylvia; Pesce Alessandra; Moens Luc; Ascenzi Paolo; Hankeln Thomas; Burmester Thorsten; Bolognesi Martino
Crystal structure of cytoglobin: the fourth globin type discovered in man displays heme hexa-coordination.
Journal of molecular biology 2004;336(4):917-27.
2004: Bocedi Alessio; Visca Paolo; Ascenzi Paolo
Can green microalgae fuel the future?
IUBMB life 2004;56(2):107-8.
2004: Putignani Lorenza; Ambrosi Cecilia; Ascenzi Paolo; Visca Paolo
Expression of L-ornithine Ndelta-oxygenase (PvdA) in fluorescent Pseudomonas species: an immunochemical and in silico study.
Biochemical and biophysical research communications 2004;313(2):245-57.
2004: Fundueanu Gheorghe; Constantin Marieta; Dalpiaz Alessandro; Bortolotti Fabrizio; Cortesi Rita; Ascenzi Paolo; Menegatti Enea
Preparation and characterization of starch/cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy) in allergic rhinitis treatment.
Biomaterials 2004;25(1):159-70.
2004: Pesce Alessandra; Dewilde Sylvia; Nardini Marco; Moens Luc; Ascenzi Paolo; Hankeln Thomas; Burmester Thorsten; Bolognesi Martino
The human brain hexacoordinated neuroglobin three-dimensional structure.
Micron (Oxford, England : 1993) 2004;35(1-2):63-5.
2003: Ascenzi Paolo; Bocedi Alessio; Gradoni Luigi
The anti-parasitic effects of nitric oxide.
IUBMB life 2003;55(10-11):573-8.
2003: Tonello Fiorella; Ascenzi Paolo; Montecucco Cesare
The metalloproteolytic activity of the anthrax lethal factor is substrate-inhibited.
The Journal of biological chemistry 2003;278(41):40075-8.
2003: Ascenzi Paolo; Bocedi Alessio; Visca Paolo; Antonini Giovanni; Gradoni Luigi
Catalytic properties of cysteine proteinases from Trypanosoma cruzi and Leishmania infantum: a pre-steady-state and steady-state study.
Biochemical and biophysical research communications 2003;309(3):659-65.
2003: Pesce Alessandra; Dewilde Sylvia; Nardini Marco; Moens Luc; Ascenzi Paolo; Hankeln Thomas; Burmester Thorsten; Bolognesi Martino
Human brain neuroglobin structure reveals a distinct mode of controlling oxygen affinity.
Structure (London, England : 1993) 2003;11(9):1087-95.
2003: Bocedi A Alessio; Ascenzi Paolo
Are specific hydrolases bioscavengers for defense against organophosphorus nerve agents?
IUBMB life 2003;55(8):491-2.
2003: Ascenzi Paolo; Clementi Emilio; Polticelli Fabio
The Rhodococcus sp. cocaine esterase: a bacterial candidate for novel pharmacokinetic-based therapies for cocaine abuse.
IUBMB life 2003;55(7):397-402.
2003: de Sanctis Daniele; Dewilde Sylvia; Pesce Alessandra; Ascenzi Paolo; Burmester Thorsten; Hankeln Thomas; Moens Luc; Bolognesi Martino
New insight into the haemoglobin superfamily: preliminary crystallographic characterization of human cytoglobin.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 7):1285-7.
2003: Spallarossa Andrea; Forlani Fabio; Pagani Silvia; Salvati Luca; Visca Paolo; Ascenzi Paolo; Bolognesi Martino; Bordo Domenico
Inhibition of Azotobacter vinelandii rhodanese by NO-donors.
Biochemical and biophysical research communications 2003;306(4):1002-7.
2003: Fundueanu Gheorghe; Constantin Marieta; Mihai Doina; Bortolotti Fabrizio; Cortesi Rita; Ascenzi Paolo; Menegatti Enea
Pullulan-cyclodextrin microspheres. A chromatographic approach for the evaluation of the drug-cyclodextrin interactions and the determination of the drug release profiles.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;791(1-2):407-19.
2003: Belenghi Beatrice; Acconcia Filippo; Trovato Maurizio; Perazzolli Michele; Bocedi Alessio; Polticelli Fabio; Ascenzi Paolo; Delledonne Massimo
AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death.
European journal of biochemistry / FEBS 2003;270(12):2593-604.
2003: Ascenzi Paolo; Bocedi Alessio; Bolognesi Martino; Spallarossa Andrea; Coletta Massimo; De Cristofaro Raimondo; Menegatti Enea
The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): a milestone protein.
Current protein & peptide science 2003;4(3):231-51.
2003: Milani Mario; Savard Pierre-Yves; Ouellet Hugues; Ascenzi Paolo; Guertin Michel; Bolognesi Martino
A TyrCD1/TrpG8 hydrogen bond network and a TyrB10TyrCD1 covalent link shape the heme distal site of Mycobacterium tuberculosis hemoglobin O.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5766-71.
2003: Fasano Mauro; Baroni Simona; Aime Silvio; Mattu Marco; Ascenzi Paolo
Determination of ferric heme-human serum albumin by 1H NMR relaxometry.
Journal of inorganic biochemistry 2003;95(1):64-7.
2003: Ciaccio Chiara; Rosati Antonella; De Sanctis Giampiero; Sinibaldi Federica; Marini Stefano; Santucci Roberto; Ascenzi Paolo; Welinder Karen G; Coletta Massimo
Relationships of ligand binding, redox properties, and protonation in Coprinus cinereus peroxidase.
The Journal of biological chemistry 2003;278(21):18730-7.
2003: Leoni Livia; Ascenzi Paolo; Bocedi Alessio; Rampioni Giordano; Castellini Laura; Zennaro Elisabetta
Styrene-catabolism regulation in Pseudomonas fluorescens ST: phosphorylation of StyR induces dimerization and cooperative DNA-binding.
Biochemical and biophysical research communications 2003;303(3):926-31.
2003: Massilia Gabriella Raybaudi; Eliseo Tommaso; Grolleau Francoise; Lapied Bruno; Barbier Julien; Bournaud Roland; Molgó Jordi; Cicero Daniel Oscar; Paci Maurizio; Schininà Maria Eugenia; Ascenzi Paolo; Polticelli Fabio
Contryphan-Vn: a modulator of Ca2+-dependent K+ channels.
Biochemical and biophysical research communications 2003;303(1):238-46.
2003: Trovato Maurizio; Casavola Elena Caroli; Maras Bruno; Schininà Maria Eugenia; Costantino Paolo; Ascenzi Paolo
Protein minimization: characterization of the synthetic cyclic dodecapeptide corresponding to the reactive site region of the oil rape trypsin inhibitor type-III.
Biochemical and biophysical research communications 2003;302(2):311-5.
2003: Ascenzi Paolo; Azzi Angelo
Can onions be engineered for not tearing?
IUBMB life 2003;55(1):49-50.
2003: Acconcia Filippo; Bocedi Alessio; Ascenzi Paolo; Marino Maria
Does palmitoylation target estrogen receptors to plasma membrane caveolae?
IUBMB life 2003;55(1):33-5.
2002: Ascenzi Paolo; Bocedi Alessio
Is there evidence that H2S (like CO and NO) may be a neuromodulator? If it is, what is the mechanism of its action?
IUBMB life 2002;54(6):371-2.
2002: Pesce Alessandra; Bolognesi Martino; Bocedi Alessio; Ascenzi Paolo; Dewilde Sylvia; Moens Luc; Hankeln Thomas; Burmester Thorsten
Neuroglobin and cytoglobin. Fresh blood for the vertebrate globin family.
EMBO reports 2002;3(12):1146-51.
2002: Venturini Giorgio; Colasanti Marco; Persichini Tiziana; Fioravanti Emanuela; Ascenzi Paolo; Palomba Letizia; Cantoni Orazio; Musci Giovanni
Beta-amyloid inhibits NOS activity by subtracting NADPH availability.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(14):1970-2.
2002: Pallottini Valentina; Marino Maria; Ascenzi Paolo
Clonidine displacement from type 1 imidazoline receptor by p-aminobenzamidine, the prototype of trypsin-like serine protease inhibitors.
IUBMB life 2002;54(5):301-4.
2002: Ascenzi Paolo; Visca Paolo; Ippolito Giuseppe; Spallarossa Andrea; Bolognesi Martino; Montecucco Cesare
Anthrax toxin: a tripartite lethal combination.
FEBS letters 2002;531(3):384-8.
2002: Ascenzi Paolo; Polticelli Fabio
May monomeric proteins be allosterically controlled?
IUBMB life 2002;54(4):223-4.
2002: Pesce Alessandra; Nardini Marco; Dewilde Sylvia; Ascenzi Paolo; Burmester Thorsten; Hankeln Thomas; Moens Luc; Bolognesi Martino
Human neuroglobin: crystals and preliminary X-ray diffraction analysis.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 2):1848-50.
2002: Visca Paolo; Fabozzi Giulia; Milani Mario; Bolognesi Martino; Ascenzi Paolo
Nitric oxide and Mycobacterium leprae pathogenicity.
IUBMB life 2002;54(3):95-9.
2002: Castelli Daniela Delli; Lovera Elena; Ascenzi Paolo; Fasano Mauro
Unfolding of the loggerhead sea turtle (Caretta caretta) myoglobin: A (1)H-NMR and electronic absorbance study.
Protein science : a publication of the Protein Society 2002;11(9):2273-8.
2002: Fasano Mauro; Mattu Marco; Coletta Massimo; Ascenzi Paolo
The heme-iron geometry of ferrous nitrosylated heme-serum lipoproteins, hemopexin, and albumin: a comparative EPR study.
Journal of inorganic biochemistry 2002;91(3):487-90.
2002: Ascenzi Paolo; Fasano Mauro; Gradoni Luigi
Do hemoglobin and hemocyanin impair schistosoma killing by no?
IUBMB life 2002;53(6):287-8.
2002: Visca Paolo; Fabozzi Giulia; Petrucca Andrea; Ciaccio Chiara; Coletta Massimo; De Sanctis Giampiero; Bolognesi Martino; Milani Mario; Ascenzi Paolo
The truncated hemoglobin from Mycobacterium leprae.
Biochemical and biophysical research communications 2002;294(5):1064-70.
2002: Pesce Alessandra; Nardini Marco; Dewilde Sylvia; Geuens Eva; Yamauchi Kiyoshi; Ascenzi Paolo; Riggs Austen F; Moens Luc; Bolognesi Martino
The 109 residue nerve tissue minihemoglobin from Cerebratulus lacteus highlights striking structural plasticity of the alpha-helical globin fold.
Structure (London, England : 1993) 2002;10(5):725-35.
2002: Milani Mario; Pesce Alessandra; Dewilde Sylvia; Ascenzi Paolo; Moens Luc; Bolognesi Martino
Structural plasticity in the eight-helix fold of a trematode haemoglobin.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):719-22.
2002: Ascenzi Paolo; Gradoni Luigi
Nitric oxide limits parasite development in vectors and in invertebrate intermediate hosts.
IUBMB life 2002;53(2):121-3.
2002: Ascenzi Paolo; Fasano Mauro; Marino Maria; Venturini Giorgio; Federico Rodolfo
Agmatine oxidation by copper amine oxidase.
European journal of biochemistry / FEBS 2002;269(3):884-92.
2002: Colasanti Marco; Gradoni Luigi; Mattu Marco; Persichini Tiziana; Salvati Luca; Venturini Giorgio; Ascenzi Paolo
Molecular bases for the anti-parasitic effect of NO (Review).
International journal of molecular medicine 2002;9(2):131-4.
2002: Salvati Luca; Bolognesi Martino; Ascenzi Paolo
Does inhibition of Trypanosoma cruzi key enzymes affect parasite life cycle and geographic distribution?
IUBMB life 2002;53(1):45-7.
2001: Colasanti M; Salvati L; Venturini G; Ascenzi P; Gradoni L
Cysteine protease as a target for nitric oxide in parasitic organisms.
Trends in parasitology 2001;17(12):575.
2001: Baroni S; Mattu M; Vannini A; Cipollone R; Aime S; Ascenzi P; Fasano M
Effect of ibuprofen and warfarin on the allosteric properties of haem-human serum albumin. A spectroscopic study.
European journal of biochemistry / FEBS 2001;268(23):6214-20.
2001: Pesce A; Nardini M; Dewilde S; Ascenzi P; Riggs A F; Yamauchi K; Geuens E; Moens L; Bolognesi M
Crystallization and preliminary X-ray analysis of neural haemoglobin from the nemertean worm Cerebratulus lacteus.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1897-9.
2001: Massilia G R; Schininà M E; Ascenzi P; Polticelli F
Contryphan-Vn: a novel peptide from the venom of the Mediterranean snail Conus ventricosus.
Biochemical and biophysical research communications 2001;288(4):908-13.
2001: Marino M; Ficca R; Ascenzi P; Trentalance A
Nitric oxide inhibits selectively the 17beta-estradiol-induced gene expression without affecting nongenomic events in HeLa cells.
Biochemical and biophysical research communications 2001;286(3):529-33.
2001: Milani M; Pesce A; Ouellet Y; Ascenzi P; Guertin M; Bolognesi M
Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme.
The EMBO journal 2001;20(15):3902-9.
2001: Giangiacomo L; Mattu M; Arcovito A; Bellenchi G; Bolognesi M; Ascenzi P; Boffi A
Monomer-dimer equilibrium and oxygen binding properties of ferrous Vitreoscilla hemoglobin.
Biochemistry 2001;40(31):9311-6.
2001: Ascenzi P; Salvati L; Brunori M
Does myoglobin protect Trypanosoma cruzi from the antiparasitic effects of nitric oxide?.
FEBS letters 2001;501(2-3):103-5.
2001: Ascenzi P; Salvati L; Bolognesi M; Colasanti M; Polticelli F; Venturini G
Inhibition of cysteine protease activity by NO-donors.
Current protein & peptide science 2001;2(2):137-53.
2001: Fasano M; Baroni S; Vannini A; Ascenzi P; Aime S
Relaxometric characterization of human hemalbumin.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2001;6(5-6):650-8.
2001: Pesce A; Dewilde S; Kiger L; Milani M; Ascenzi P; Marden M C; Van Hauwaert M L; Vanfleteren J; Moens L; Bolognesi M
Very high resolution structure of a trematode hemoglobin displaying a TyrB10-TyrE7 heme distal residue pair and high oxygen affinity.
Journal of molecular biology 2001;309(5):1153-64.
2001: Salvati L; Mattu M; Polticelli F; Tiberi F; Gradoni L; Venturini G; Bolognesi M; Ascenzi P
Modulation of the catalytic activity of cruzipain, the major cysteine proteinase from Trypanosoma cruzi, by temperature and pH.
European journal of biochemistry / FEBS 2001;268(11):3253-8.
2001: Mattu M; Vannin A; Coletta M; Fasano M; Ascenzi P
Effect of bezafibrate and clofibrate on the heme-iron geometry of ferrous nitrosylated heme-human serum albumin: an EPR study.
Journal of inorganic biochemistry 2001;84(3-4):293-6.
2001: Binda C; Angelini R; Federico R; Ascenzi P; Mattevi A
Structural bases for inhibitor binding and catalysis in polyamine oxidase.
Biochemistry 2001;40(9):2766-76.
2001: Salvati L; Mattu M; Colasanti M; Scalone A; Venturini G; Gradoni L; Ascenzi P
NO donors inhibit Leishmania infantum cysteine proteinase activity.
Biochimica et biophysica acta 2001;1545(1-2):357-66.
2001: Erba F; Fiorucci L; Pascarella S; Menegatti E; Ascenzi P; Ascoli F
Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug.
Biochemical pharmacology 2001;61(3):271-6.
2001: Salvati L; Mattu M; Tiberi F; Polticelli F; Ascenzi P
Inhibition of Saccharomyces cerevisiae phosphomannose isomerase by the NO-donor S-nitroso-acetyl-penicillamine.
Journal of enzyme inhibition 2001;16(3):287-92.
2001: Federico R; Leone L; Botta M; Binda C; Angelini R; Venturini G; Ascenzi P
Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study.
Journal of enzyme inhibition 2001;16(2):147-55.
2000: Ruoppolo M; Amoresano A; Pucci P; Pascarella S; Polticelli F; Trovato M; Menegatti E; Ascenzi P
Characterization of five new low-molecular-mass trypsin inhibitors from white mustard (Sinapis alba L.) seed.
European journal of biochemistry / FEBS 2000;267(21):6486-92.
2000: Trovato M; Maras B; Polticelli F; Costantino P; Ascenzi P
A chimeric mini-trypsin inhibitor derived from the oil rape proteinase inhibitor type III.
Biochemical and biophysical research communications 2000;275(3):817-20.
2000: Venturini G; Colasanti M; Persichini T; Fioravanti E; Federico R; Ascenzi P
Selective inhibition of nitric oxide synthase type I by clonidine, an anti-hypertensive drug.
Biochemical pharmacology 2000;60(4):539-44.
2000: Ascenzi P; Colasanti M; Persichini T; Muolo M; Polticelli F; Venturini G; Bordo D; Bolognesi M
Re-evaluation of amino acid sequence and structural consensus rules for cysteine-nitric oxide reactivity.
Biological chemistry 2000;381(7):623-7.
2000: Pesce A; Couture M; Dewilde S; Guertin M; Yamauchi K; Ascenzi P; Moens L; Bolognesi M
A novel two-over-two alpha-helical sandwich fold is characteristic of the truncated hemoglobin family.
The EMBO journal 2000;19(11):2424-34.
2000: Venturini G; Salvati L; Muolo M; Colasanti M; Gradoni L; Ascenzi P
Nitric oxide inhibits cruzipain, the major papain-like cysteine proteinase from Trypanosoma cruzi.
Biochemical and biophysical research communications 2000;270(2):437-41.
2000: Ascenzi P; Balliano G; Gallina C; Polticelli F; Bolognesi M
Serine proteinase inhibition by the active site titrant N alpha-(N, N-dimethylcarbamoyl)-alpha-azaornithine p-nitrophenyl ester. A comparative study.
European journal of biochemistry / FEBS 2000;267(4):1239-46.
2000: Venturini G; Colasanti M; Salvati L; Gradoni L; Ascenzi P
Nitric oxide inhibits falcipain, the Plasmodium falciparum trophozoite cysteine protease.
Biochemical and biophysical research communications 2000;267(1):190-3.
1999: Polticelli F; Pascarella S; Bordo D; Bolognesi M; Ascenzi P
The T-knot motif revisited.
Biological chemistry 1999;380(10):1247-50.
1999: Venturini G; Colasanti M; Fioravanti E; Bianchini A; Ascenzi P
Direct effect of temperature on the catalytic activity of nitric oxide synthases types I, II, and III.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1999;3(5):375-82.
1999: Ascenzi P; Bertollini A; Coletta M; Lucacchini A
Stabilization of the T-state of ferrous human adult haemoglobin by chlorpromazine and trifluoperazine.
Biotechnology and applied biochemistry 1999;30 ( Pt 2)():185-7.
1999: Bolognesi M; Boffi A; Coletta M; Mozzarelli A; Pesce A; Tarricone C; Ascenzi P
Anticooperative ligand binding properties of recombinant ferric Vitreoscilla homodimeric hemoglobin: a thermodynamic, kinetic and X-ray crystallographic study.
Journal of molecular biology 1999;291(3):637-50.
1999: Colasanti M; Persichini T; Venturini G; Ascenzi P
S-nitrosylation of viral proteins: molecular bases for antiviral effect of nitric oxide.
IUBMB life 1999;48(1):25-31.
1999: Caccuri A M; Antonini G; Ascenzi P; Nicotra M; Nuccetelli M; Mazzetti A P; Federici G; Lo Bello M; Ricci G
Temperature adaptation of glutathione S-transferase P1-1. A case for homotropic regulation of substrate binding.
The Journal of biological chemistry 1999;274(27):19276-80.
1999: Ascenzi P; Colasanti M; Fasano M; Bertollini A
Stabilization of the T-state of human hemoglobin by proflavine, an antiseptic drug.
Biochemistry and molecular biology international 1999;47(6):991-5.
1999: Persichini T; Colasanti M; Fraziano M; Colizzi V; Medana C; Polticelli F; Venturini G; Ascenzi P
Nitric oxide inhibits the HIV-1 reverse transcriptase activity.
Biochemical and biophysical research communications 1999;258(3):624-7.
1999: Aime S; Digilio G; Fasano M; Paoletti S; Arnelli A; Ascenzi P
Metal complexes as allosteric effectors of human hemoglobin: an NMR study of the interaction of the gadolinium(III) bis(m-boroxyphenylamide)diethylenetriaminepentaacetic acid complex with human oxygenated and deoxygenated hemoglobin.
Biophysical journal 1999;76(5):2735-43.
1999: Ascenzi P; Ruoppolo M; Amoresano A; Pucci P; Consonni R; Zetta L; Pascarella S; Bortolotti F; Menegatti E
Characterization of low-molecular-mass trypsin isoinhibitors from oil-rape (Brassica napus var. oleifera) seed.
European journal of biochemistry / FEBS 1999;261(1):275-84.
1999: Binda C; Coda A; Angelini R; Federico R; Ascenzi P; Mattevi A
A 30-angstrom-long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase.
Structure (London, England : 1993) 1999;7(3):265-76.
1999: Coletta M; Angeletti M; Ascenzi P; Bertollini A; Della Longa S; De Sanctis G; Priori A M; Santucci R; Amiconi G
Coupling of the oxygen-linked interaction energy for inositol hexakisphosphate and bezafibrate binding to human HbA0.
The Journal of biological chemistry 1999;274(11):6865-74.
1999: Persichini T; Colasanti M; Fraziano M; Colizzi V; Ascenzi P; Lauro G M
Nitric oxide inhibits HIV-1 replication in human astrocytoma cells.
Biochemical and biophysical research communications 1999;254(1):200-2.
1998: Binda C; Coda A; Angelini R; Federico R; Ascenzi P; Mattevi A
Crystallization and preliminary X-ray analysis of polyamine oxidase from Zea mays L.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 6 Pt 2):1429-31.
1998: Ascenzi P; Bolognesi M; Catalucci D; Pascarella S; Ruoppolo M; Rizzi M
Leech antihemostatic proteins share the T-knot scaffold, a disulfide-reinforced structural motif.
Biological chemistry 1998;379(11):1387-9.
1998: Colasanti M; Persichini T; Fabrizi C; Cavalieri E; Venturini G; Ascenzi P; Lauro G M; Suzuki H
Expression of a NOS-III-like protein in human astroglial cell culture.
Biochemical and biophysical research communications 1998;252(3):552-5.
1998: Cortesi R; Ascenzi P; Colasanti M; Persichini T; Venturini G; Bolognesi M; Pesce A; Nastruzzi C; Menegatti E
Cross-enzyme inhibition by gabexate mesylate: formulation and reactivity study.
Journal of pharmaceutical sciences 1998;87(11):1335-40.
1998: Venturini G; Fioravanti E; Colasanti M; Persichini T; Ascenzi P
Cys25-nitrosylation inactivates papain.
Biochemistry and molecular biology international 1998;46(2):425-8.
1998: Ercolini L; Angelini R; Federico R; Rea G; Venturini G; Ascenzi P
Competitive inhibition of Lens culinaris L. copper amine oxidase by amiloride, p-aminobenzamidine, clonidine, 4',6-diamidino-2-phenylindole and gabexate mesylate: a comparative study.
Journal of enzyme inhibition 1998;13(6):465-71.
1998: Persichini T; Colasanti M; Lauro G M; Ascenzi P
Cysteine nitrosylation inactivates the HIV-1 protease.
Biochemical and biophysical research communications 1998;250(3):575-6.
1998: Aime S; Fasano M; Paoletti S; Bellelli A; Coletta M; Ascenzi P
Stabilization of the T-state of ferrous human adult and fetal hemoglobin by Ln(III) complexes: a thermodynamic study.
Journal of inorganic biochemistry 1998;71(1-2):37-43.
1998: Venturini G; Colasanti M; Ascenzi P
Aprotinin, the first competitive protein inhibitor of NOS activity.
Biochemical and biophysical research communications 1998;249(1):263-5.
1998: Colasanti M; Persichini T; Venturini G; Menegatti E; Lauro G M; Ascenzi P
Effect of gabexate mesylate (FOY), a drug for serine proteinase-mediated diseases, on the nitric oxide pathway.
Biochemical and biophysical research communications 1998;246(2):453-6.
1998: Coletta M; Ascenzi P; Polizio F; Smulevich G; del Gaudio R; Piscopo M; Geraci G
Cooperative mechanism in the homodimeric myoglobin from Nassa mutabilis.
Biochemistry 1998;37(9):2873-8.
1997: Federico R; Angelini R; Ercolini L; Venturini G; Mattevi A; Ascenzi P
Competitive inhibition of swine kidney copper amine oxidase by drugs: amiloride, clonidine, and gabexate mesylate.
Biochemical and biophysical research communications 1997;240(1):150-2.
1997: Ascenzi P; Federico R; Menegatti E; Venturini G
Competitive inhibition of mouse brain nitric oxide synthase by amiloride: a case for enzyme cross-inhibition.
Biochemistry and molecular biology international 1997;43(3):507-11.
1997: De Simone G; Balliano G; Milla P; Gallina C; Giordano C; Tarricone C; Rizzi M; Bolognesi M; Ascenzi P
Human alpha-thrombin inhibition by the highly selective compounds N-ethoxycarbonyl-D-Phe-Pro-alpha-azaLys p-nitrophenyl ester and N-carbobenzoxy-Pro-alpha-azaLys p-nitrophenyl ester: a kinetic, thermodynamic and X-ray crystallographic study.
Journal of molecular biology 1997;269(4):558-69.
1997: Antonini G; Pitari G; Caccuri A M; Ricci G; Boschi D; Fruttero R; Gasco A; Ascenzi P
Inhibition of human placenta glutathione transferase P1-1 by the antibiotic calvatic acid and its diazocyanide analogue--evidence for multiple catalytic intermediates.
European journal of biochemistry / FEBS 1997;245(3):663-7.
1997: Tarricone C; Galizzi A; Coda A; Ascenzi P; Bolognesi M
Unusual structure of the oxygen-binding site in the dimeric bacterial hemoglobin from Vitreoscilla sp.
Structure (London, England : 1993) 1997;5(4):497-507.
1997: Venturini G; Menegatti E; Ascenzi P
Competitive inhibition of nitric oxide synthase by p-aminobenzamidine, a serine proteinase inhibitor.
Biochemical and biophysical research communications 1997;232(1):88-90.
1997: Capasso C; Rizzi M; Menegatti E; Ascenzi P; Bolognesi M
Crystal structure of the bovine alpha-chymotrypsin:Kunitz inhibitor complex. An example of multiple protein:protein recognition sites.
Journal of molecular recognition : JMR 1997;10(1):26-35.
1997: Tarricone C; Calogero S; Galizzi A; Coda A; Ascenzi P; Bolognesi M
Expression, purification, crystallization, and preliminary X-ray diffraction analysis of the homodimeric bacterial hemoglobin from Vitreoscilla stercoraria.
Proteins 1997;27(1):154-6.
1997: Bolognesi M; Bordo D; Rizzi M; Tarricone C; Ascenzi P
Nonvertebrate hemoglobins: structural bases for reactivity.
Progress in biophysics and molecular biology 1997;68(1):29-68.
1996: Coletta M; Ascenzi P; D'Avino R; di Prisco G
Proton-linked subunit kinetic heterogeneity for carbon monoxide binding to hemoglobin from Chelidonichthys kumu.
The Journal of biological chemistry 1996;271(47):29859-64.
1996: Balliano G; Milla P; Giordano C; Gallina C; Coletta M; Menegatti E; Rizzi M; Bolognesi M; Ascenzi P
N-ethoxycarbonyl-D-phenylalanyl-L-prolyl-alpha-azalysine p-nitrophenyl ester: a novel, high selective and optimal chromogenic active site titrant for human and bovine alpha-, beta- and gamma-thrombin.
Biochemical and biophysical research communications 1996;225(2):557-61.
1996: Aime S; Fasano M; Paoletti S; Viola F; Tarricone C; Ascenzi P
1H-NMR relaxometric study of pancreatic serine (pro)enzyme inhibition by a Gd(III) chelate bearing boronic functionalities.
Biochemistry and molecular biology international 1996;39(4):741-6.
1996: Caccuri A M; Ascenzi P; Antonini G; Parker M W; Oakley A J; Chiessi E; Nuccetelli M; Battistoni A; Bellizia A; Ricci G
Structural flexibility modulates the activity of human glutathione transferase P1-1. Influence of a poor co-substrate on dynamics and kinetics of human glutathione transferase.
The Journal of biological chemistry 1996;271(27):16193-8.
1996: Nardini M; Pesce A; Rizzi M; Casale E; Ferraccioli R; Balliano G; Milla P; Ascenzi P; Bolognesi M
Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
Journal of molecular biology 1996;258(5):851-9.
1996: Viola F; Aime S; Coletta M; Desideri A; Fasano M; Paoletti S; Tarricone C; Ascenzi P
Azide, cyanide, fluoride, imidazole and pyridine binding to ferric and ferrous native horse heart cytochrome c and to its carboxymethylated derivative: a comparative study.
Journal of inorganic biochemistry 1996;62(3):213-22.
1996: Rizzi M; Wittenberg J B; Coda A; Ascenzi P; Bolognesi M
Structural bases for sulfide recognition in Lucina pectinata hemoglobin I.
Journal of molecular biology 1996;258(1):1-5.
1996: Aime S; Fasano M; Paoletti S; Cutruzzolà F; Desideri A; Bolognesi M; Rizzi M; Ascenzi P
Structural determinants of fluoride and formate binding to hemoglobin and myoglobin: crystallographic and 1H-NMR relaxometric study.
Biophysical journal 1996;70(1):482-8.
1996: Coletta M; Angeletti M; De Sanctis G; Cerroni L; Giardina B; Amiconi G; Ascenzi P
Kinetic evidence for the existence of a rate-limiting step in the reaction of ferric hemoproteins with anionic ligands.
European journal of biochemistry / FEBS 1996;235(1-2):49-53.
1995: Ascenzi P; Balliano G; Milla P; Ferraccioli R; Sartori P; Djinovic-Carugo K; Bolognesi M
Inhibition of bovine beta-trypsin by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azaornithine p-nitrophenyl ester: a kinetic and X-ray crystallographic study.
Biochemical and biophysical research communications 1995;217(2):437-44.
1995: Aime S; Fasano M; Paoletti S; Arnelli A; Ascenzi P
NMR relaxometric investigation on human methemoglobin and fluoromethemoglobin. An improved quantitative in vitro assay of human methemoglobin.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1995;33(6):827-31.
1995: Fruttero R; Amiconi G; Ascoli F; Bolognesi M; Ascenzi P
Identification of L-methionine oxidation products in tripeptides, in Met-enkephalin and in the bovine basic pancreatic trypsin inhibitor: 1H and 13C NMR study.
Biochemistry and molecular biology international 1995;35(4):861-74.
1995: Nardini M; Tarricone C; Rizzi M; Lania A; Desideri A; De Sanctis G; Coletta M; Petruzzelli R; Ascenzi P; Coda A
Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0 A resolution.
Journal of molecular biology 1995;247(3):459-65.
1995: Casale E; Collyer C; Ascenzi P; Balliano G; Milla P; Viola F; Fasano M; Menegatti E; Bolognesi M
Inhibition of bovine beta-trypsin, human alpha-thrombin and porcine pancreatic beta-kallikrein-B by 4',6-diamidino-2-phenylindole, 6-amidinoindole and benzamidine: a comparative thermodynamic and X-ray structural study.
Biophysical chemistry 1995;54(1):75-81.
1995: Leci E; Brancaccio A; Cutruzzolà F; Allocatelli C T; Tarricone C; Bolognesi M; Desideri A; Ascenzi P
Formate binding to ferric wild type and mutant myoglobins thermodynamic and X-ray crystallographic study.
FEBS letters 1995;357(3):227-9.
1995: Sartori P; Djinovic Carugo K; Ferraccioli R; Balliano G; Milla P; Ascenzi P; Bolognesi M
Active site titration of bovine beta-trypsin by N alpha-(N,N-dimethylcarbamoyl)-alpha-aza-lysine p-nitrophenyl ester: kinetic and crystallographic analysis.
FEBS letters 1995;358(1):53-6.
1995: Ascenzi P; Amiconi G; Bode W; Bolognesi M; Coletta M; Menegatti E
Proteinase inhibitors from the European medicinal leech Hirudo medicinalis: structural, functional and biomedical aspects.
Molecular aspects of medicine 1995;16(3):215-313.
1994: Rizzi M; Wittenberg J B; Coda A; Fasano M; Ascenzi P; Bolognesi M
Structure of the sulfide-reactive hemoglobin from the clam Lucina pectinata. Crystallographic analysis at 1.5 A resolution.
Journal of molecular biology 1994;244(1):86-99.
1994: Caccuri A M; Ascenzi P; Lo Bello M; Federici G; Battistoni A; Mazzetti P; Ricci G
Are the steady state kinetics of glutathione transferase always dependent on the deprotonation of the bound glutathione? New insights in the kinetic mechanism of GST P 1-1.
Biochemical and biophysical research communications 1994;200(3):1428-34.
1994: Ceciliani F; Bortolotti F; Menegatti E; Ronchi S; Ascenzi P; Palmieri S
Purification, inhibitory properties, amino acid sequence and identification of the reactive site of a new serine proteinase inhibitor from oil-rape (Brassica napus) seed.
FEBS letters 1994;342(2):221-4.
1994: Bolognesi M; Djinovic-Carugo K; Ascenzi P
Molecular bases for human leucocyte elastase inhibition.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo 1994;49(2):144-9.
1994: Ascenzi P; Coletta M; Santucci R; Polizio F; Desideri A
Nitric oxide binding to ferrous native horse heart cytochrome c and to its carboxymethylated derivative: a spectroscopic and thermodynamic study.
Journal of inorganic biochemistry 1994;53(4):273-80.
1994: Tomova S; Cutruzzolà F; Barra D; Amiconi G; Ascenzi P; Djinovic Carugo K; Menegatti E; Sarti P; Schnebli H P; Bolognesi M
Selective oxidation of methionyl residues in the human recombinant secretory leukocyte proteinase inhibitor. Effect on the inhibitor binding properties.
Journal of molecular recognition : JMR 1994;7(1):31-7.
1994: Oddone R; Barra D; Amiconi G; Ascenzi P; Tarricone C; Bolognesi M; Bortolotti F; Menegatti E
Binding of native and [homoserine lactone-52]-52,53-seco-bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor) to porcine pancreatic beta-kallikrein-B and bovine alpha-chymotrypsin: thermodynamic study.
Journal of molecular recognition : JMR 1994;7(1):39-46.
1993: Ascenzi P; Clementi M E; Condò S G; Coletta M; Petruzzelli R; Polizio F; Rizzi M; Giunta C; Peracino V; Giardina B
Functional, spectroscopic and structural properties of haemoglobin from chamois (Rupicapra rupicapra) and steinbock (Capra hircus ibex).
The Biochemical journal 1993;296 ( Pt 2)():361-5.
1993: Qin J; Pande U; La Mar G N; Ascoli F; Ascenzi P; Cutruzzolá F; Travaglini-Allocatelli C; Brunori M
1H NMR study of the dynamics of the pH modulation of axial coordination in Aplysia limacina (Val(E7)) and sperm whale double mutant His(E7)-->Val,Thr(E10)-->Arg metmyoglobin.
The Journal of biological chemistry 1993;268(32):24012-21.
1993: Conti E; Moser C; Rizzi M; Mattevi A; Lionetti C; Coda A; Ascenzi P; Brunori M; Bolognesi M
X-ray crystal structure of ferric Aplysia limacina myoglobin in different liganded states.
Journal of molecular biology 1993;233(3):498-508.
1993: Petruzzelli R; Aureli G; Casale E; Nardini M; Rizzi M; Ascenzi P; Coletta M; De Sanctis G; Desideri A; Galtieri A
Structural studies on the loggerhead sea turtle (Caretta caretta) myoglobin.
Biochemistry and molecular biology international 1993;31(1):19-24.
1993: Ascenzi P; Bertollini A; Coletta M; Desideri A; Giardina B; Polizio F; Santucci R; Scatena R; Amiconi G
Cooperative effect of inositol hexakisphosphate, bezafibrate, and clofibric acid on the spectroscopic properties of the nitric oxide derivative of ferrous human hemoglobin.
Journal of inorganic biochemistry 1993;50(4):263-72.
1993: Djinovic Carugo K; Rizzi M; Fasano M; Luisetti M; La Rosa C; Ascenzi P; Bolognesi M
Inhibition of serine proteinases belonging to the chymotrypsin superfamily by the cyclic thiolic compound YS3025: a comparative crystallographic study.
Biochemical and biophysical research communications 1993;193(1):32-9.
1993: Coletta M; Ascenzi P; Santucci R; Bertollini A; Amiconi G
Interaction of inositol hexakisphosphate with liganded ferrous human hemoglobin. Direct evidence for two functionally operative binding sites.
Biochimica et biophysica acta 1993;1162(3):309-14.
1993: Cutruzzolá F; Ascenzi P; Barra D; Bolognesi M; Menegatti E; Sarti P; Schnebli H P; Tomova S; Amiconi G
Selective oxidation of Met-192 in bovine alpha-chymotrypsin. Effect on catalytic and inhibitor binding properties.
Biochimica et biophysica acta 1993;1161(2-3):201-8.
1993: Fioretti E; Angeletti M; Coletta M; Ascenzi P; Bolognesi M; Menegatti E; Rizzi M; Ascoli F
Binding of bovine basic pancreatic trypsin inhibitor (Kunitz) as well as bovine and porcine pancreatic secretory trypsin inhibitor (Kazal) to human cathepsin G: a kinetic and thermodynamic study.
Journal of enzyme inhibition 1993;7(1):57-64.
1992: Aime S; Dastrú W; Fasano M; Arnelli A; Castagnola M; Giardina B; Ascenzi P
Quantitative determination of methemoglobin by measuring the solvent-water proton-nuclear magnetic resonance relaxation rate.
Clinical chemistry 1992;38(12):2401-4.
1992: Rizzi M; Casale E; Coda A; La Rosa C; Ascenzi P; Luisetti M; Bolognesi M
Serine proteinase inhibition by the cyclic thiolic compound YS3025: a crystallographic study.
Biochemistry international 1992;28(3):385-92.
1992: Ascenzi P; Coletta M; Desideri A; Polizio F; Bertollini A; Santucci R; Amiconi G
Effect of bezafibrate and clofibric acid on the spectroscopic properties of the nitric oxide derivative of ferrous human hemoglobin.
Journal of inorganic biochemistry 1992;48(1):47-53.
1992: Conti E; Casale E; Ascenzi P; Coletta M; Condo S G; Merli A; Giardina B; Bordo D; Bolognesi M
Structural study and preliminary crystallographic data for the hemoglobin from reindeer (Rangifer tarandus tarandus)
Biochemical and biophysical research communications 1992;187(2):1063-70.
1992: Giardina B; Galtieri A; Lania A; Ascenzi P; Desideri A; Cerroni L; Condo S G
Reduced sensitivity of O2 transport to allosteric effectors and temperature in loggerhead sea turtle hemoglobin: functional and spectroscopic study.
Biochimica et biophysica acta 1992;1159(2):129-33.
1992: Onesti S; Matthews D J; Aducci P; Amiconi G; Bolognesi M; Menegatti E; Ascenzi P
Binding of the Kunitz-type trypsin inhibitor DE-3 from Erythrina caffra seeds to serine proteinases: a comparative study.
Journal of molecular recognition : JMR 1992;5(3):105-14.
1992: Frigerio F; Coda A; Pugliese L; Lionetti C; Menegatti E; Amiconi G; Schnebli H P; Ascenzi P; Bolognesi M
Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin c complex at 2.0 A resolution.
Journal of molecular biology 1992;225(1):107-23.
1992: Ascenzi P; Amiconi G; Coletta M; Lupidi G; Menegatti E; Onesti S; Bolognesi M
Binding of hirudin to human alpha, beta and gamma-thrombin. A comparative kinetic and thermodynamic study.
Journal of molecular biology 1992;225(1):177-84.
1992: Menegatti E; Tedeschi G; Ronchi S; Bortolotti F; Ascenzi P; Thomas R M; Bolognesi M; Palmieri S
Purification, inhibitory properties and amino acid sequence of a new serine proteinase inhibitor from white mustard (Sinapis alba L.) seed.
FEBS letters 1992;301(1):10-4.
1992: Coletta M; Clementi M E; Ascenzi P; Petruzzelli R; Condò S G; Giardina B
A comparative study of the temperature dependence of the oxygen-binding properties of mammalian hemoglobins.
European journal of biochemistry / FEBS 1992;204(3):1155-7.
1992: Coletta M; Ascenzi P; Smulevich G; Mantini A R; Del Gaudio R; Piscopo M; Geraci G
Alteration of the proximal bond energy in the unliganded form of the homodimeric myoglobin from Nassa mutabilis. Kinetic and spectroscopic evidence.
FEBS letters 1992;296(2):184-6.
1992: Ascenzi P; Coletta M; Desideri A; Petruzzelli R; Polizio F; Bolognesi M; Condò S G; Giardina B
Spectroscopic properties of the nitric oxide derivative of ferrous man, horse, and ruminant hemoglobins: a comparative study.
Journal of inorganic biochemistry 1992;45(1):31-7.
1992: Ascenzi P; Fruttero R; Amiconi G; Pugliese L; Bolognesi M; Coletta M; Onesti S; Guarneri M; Menegatti E
Inhibition of human alpha-, beta- and gamma-thrombin by mono-, bis-, tris- and tetra-benzamidine structures: thermodynamic study.
Journal of enzyme inhibition 1992;6(2):131-9.
1991: Casale E; Lionetti C; Coda A; Merli A; Ascenzi P; Wittenberg J B; Bolognesi M
Crystallization and preliminary data for the ferric form of Lucina pectinata hemoglobin I.
Journal of molecular biology 1991;222(3):447-9.
1991: Congiu Castellano A; Della Longa S; Bianconi A; Barteri M; Burattini E; Ascenzi P; Coletta M; Santucci R; Amiconi G
Influence of allosteric effectors on the heme conformation of dromedary ferrous nitrosylhemoglobin detected by XANES spectroscopy.
Biochimica et biophysica acta 1991;1080(2):119-25.
1991: Ascenzi P; Aducci P; Amiconi G; Ballio A; Guaragna A; Menegatti E; Schnebli H P; Bolognesi M
Binding of the recombinant proteinase inhibitor eglin c from leech Hirudo medicinalis to serine (pro)enzymes: a comparative thermodynamic study.
Journal of molecular recognition : JMR 1991;4(4):113-9.
1991: Cutruzzolà F; Allocatelli C T; Ascenzi P; Bolognesi M; Sligar S G; Brunori M
Control and recognition of anionic ligands in myoglobin.
FEBS letters 1991;282(2):281-4.
1991: Lionetti C; Guanziroli M G; Frigerio F; Ascenzi P; Bolognesi M
X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution.
Journal of molecular biology 1991;217(3):409-12.
1991: Mattevi A; Gatti G; Coda A; Rizzi M; Ascenzi P; Brunori M; Bolognesi M
Binding mode of azide to ferric Aplysia limacina myoglobin. Crystallographic analysis at 1.9 A resolution.
Journal of molecular recognition : JMR 1991;4(1):1-6.
1991: Ascenzi P; Amiconi G; Ballio A; Bolognesi M; Menegatti E; Schnebli H P; Aducci P
Binding of the recombinant proteinase inhibitor eglin c, of the soybean Bowman-Birk proteinase inhibitor and of its chymotrypsin and trypsin inhibiting fragments to Leu-proteinase, the leucine specific serine proteinase from spinach (Spinacia oleracea L.) leaves: thermodynamic study.
Journal of enzyme inhibition 1991;4(4):283-8.
1991: Ascenzi P; Amiconi G; Bolognesi M; Onesti S; Petruzzelli R; Menegatti E
Binding of the bovine and porcine pancreatic secretory trypsin inhibitor (Kazal) to human leukocyte elastase: a thermodynamic study.
Journal of enzyme inhibition 1991;5(3):207-13.
1990: Ascenzi P; Bolognesi M; Coletta M; Menegatti E; Amiconi G
[Hirudin inhibition of human thrombin activity]
Medicina (Florence, Italy) 1990;10(4):391-2.
1990: Ascenzi P; Amiconi G; Bolognesi M; Menegatti E; Guarneri M
Binding of the soybean Bowman-Birk proteinase inhibitor and of its chymotrypsin and trypsin inhibiting fragments to bovine alpha-chymotrypsin and bovine beta-trypsin. A thermodynamic study.
Journal of molecular recognition : JMR 1990;3(5-6):192-6.
1990: Ascenzi P; Coletta M; Desideri A; Polizio F; Condò S G; Giardina B
Effect of inositol hexakisphosphate on the spectroscopic properties of the nitric oxide derivative of ferrous horse and bovine hemoglobin.
Journal of inorganic biochemistry 1990;40(2):157-62.
1990: Coletta M; Ascenzi P; Amiconi G; Bolognesi M; Guarneri M; Menegatti E
Bovine trypsinogen activation. A thermodynamic study.
Biophysical chemistry 1990;37(1-3):355-62.
1990: Bolognesi M; Pugliese L; Gatti G; Frigerio F; Coda A; Antolini L; Schnebli H P; Menegatti E; Amiconi G; Ascenzi P
X-ray crystal structure of the bovine alpha-chymotrypsin/eglin c complex at 2.6 A resolution.
Journal of molecular recognition : JMR 1990;3(4):163-8.
1990: Ascenzi P; Amiconi G; Bolognesi M; Menegatti E; Guarneri M
Binding of the bovine basic pancreatic trypsin inhibitor (Kunitz) to human Glu1-, Lys77-, Val442-, and Val561-plasmin: a comparative study.
Biochimica et biophysica acta 1990;1040(1):134-6.
1990: Bolognesi M; Coda A; Frigerio F; Gatti G; Ascenzi P; Brunori M
X-ray crystal structure of the fluoride derivative of Aplysia limacina ferric myoglobin at 2.0 A resolution. Stabilization of the fluoride ion by hydrogen bonding to Arg66 (E10).
Journal of molecular biology 1990;213(4):621-5.
1990: Ascenzi P; Coletta M; Amiconi G; Bolognesi M; Menegatti E; Guarneri M
Binding of the bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor) to human and bovine factor Xa. A thermodynamic study.
Biological chemistry Hoppe-Seyler 1990;371(5):389-93.
1990: Coletta M; Boffi A; Ascenzi P; Brunori M; Chiancone E
A novel mechanism of heme-heme interaction in the homodimeric hemoglobin from Scapharca inaequivalvis as manifested upon cleavage of the proximal Fe-N epsilon bond at low pH.
The Journal of biological chemistry 1990;265(9):4828-30.
1990: Coletta M; Ascenzi P; Bravin L; Amiconi G; Bolognesi M; Guarneri M; Menegatti E
Thermodynamic modeling of internal equilibria involved in the activation of trypsinogen.
Journal of biomolecular structure & dynamics 1990;7(4):959-72.
1990: Ascenzi P; Amiconi G; Bolognesi M; Menegatti E; Guarneri M
Binding of the bovine basic pancreatic trypsin inhibitor (Kunitz) to the 33,000 Mr and 54,000 Mr species of human urokinase: thermodynamic study.
Journal of enzyme inhibition 1990;4(1):51-5.
1989: Ascenzi P; Menegatti E; Guarneri M; Amiconi G
Trypsin-like serine proteinase action: determination of the catalytic parameters KS, k+2 and k/3 under conditions where the substrate exceeds the enzyme concentration.
Biochimica et biophysica acta 1989;998(2):210-4.
1989: Menegatti E; Scalia S; Bortolotti F; Ascenzi P; De Marco A
Controlled proteolysis of mouse epidermal growth factor. An RP-HPLC and 1H-n.m.r. study.
International journal of peptide and protein research 1989;34(3):161-5.
1989: Pugliese L; Gatti G; Bolognesi M; Coda A; Menegatti E; Schnebli H P; Ascenzi P; Amiconi G
Preliminary crystallographic data on the complex of bovine alpha-chymotrypsin with the recombinant proteinase inhibitor eglin c from Hirudo medicinalis.
Journal of molecular biology 1989;208(3):511-3.
1989: Ascenzi P; Amiconi G; Rossi E; Segre A L
Binding of inositol hexakisphosphate to the oxygenated derivative of dromedary (Camelus dromedarius) and human hemoglobin: 31P-NMR study.
Journal of inorganic biochemistry 1989;35(4):247-53.
1989: Ascenzi P; Brunori M; Coletta M; Desideri A
pH effects on the haem iron co-ordination state in the nitric oxide and deoxy derivatives of ferrous horseradish peroxidase and cytochrome c peroxidase.
The Biochemical journal 1989;258(2):473-8.
1989: Bolognesi M; Onesti S; Gatti G; Coda A; Ascenzi P; Brunori M
Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution.
Journal of molecular biology 1989;205(3):529-44.
1989: Menegatti E; Guaneri M; Bolognesi M; Ascenzi P; Amiconi G
Inhibition of serine proteinases by p-carbethoxyphenyl esters of epsilon-guanidino- and epsilon-amino caproic acid: thermodynamic and molecular modeling study.
Journal of enzyme inhibition 1989;2(4):249-59.
1988: Coletta M; Ascenzi P; Brunori M
Kinetic evidence for a role of heme geometry on the modulation of carbon monoxide reactivity in human hemoglobin.
The Journal of biological chemistry 1988;263(34):18286-9.
1988: Ascenzi P; Coletta M; Amiconi G; de Cristofaro R; Bolognesi M; Guarneri M; Menegatti E
Binding of the bovine basic pancreatic trypsin inhibitor (Kunitz) to human alpha-, beta- and gamma-thrombin; a kinetic and thermodynamic study.
Biochimica et biophysica acta 1988;956(2):156-61.
1988: Ascenzi P; Desideri A; Amiconi G; Bertollini A; Bolognesi M; Castagnola M; Coletta M; Brunori M
Effect of inositol hexakisphosphate on the spectroscopic properties of the nitric oxide derivative of ferrous naturally glycated human hemoglobin HbA1c.
Journal of inorganic biochemistry 1988;34(1):19-24.
1988: Ascenzi P; Coletta M; Amiconi G; Bolognesi M; Guarneri M; Menegatti E
Zymogen activation: effect of peptides sequentially related to the bovine beta-trypsin N-terminus on Kazal inhibitor and benzamidine binding to bovine trypsinogen.
Journal of molecular recognition : JMR 1988;1(3):130-7.
1988: Ascenzi P; Santucci R; Desideri A; Amiconi G
Effect of polyanions on the spectroscopic properties of the nitric oxide derivative of ferrous dromedary (Camelus dromedarius) hemoglobin.
Journal of inorganic biochemistry 1988;32(4):225-32.
1988: Ferroni R; Menegatti E; Guarneri M; Taddeo U; Ascenzi P; Amiconi G
Aromatic amidines: inhibitory effect on purified plasma serine proteinases, blood coagulation and platelet aggregation.
Il Farmaco; edizione scientifica 1988;43(1):5-13.
1988: Ascenzi P; Amiconi G; Menegatti E; Guarneri M; Bolognesi M; Schnebli H P
Binding of the recombinant proteinase inhibitor eglin c from leech Hirudo medicinalis to human leukocyte elastase, bovine alpha-chymotrypsin and subtilisin Carlsberg: thermodynamic study.
Journal of enzyme inhibition 1988;2(3):167-72.
1987: Menegatti E; Guarneri M; Bolognesi M; Ascenzi P; Amiconi G
Binding of the bovine pancreatic secretory trypsin inhibitor (Kazal) to bovine serine (pro)enzymes.
Journal of molecular biology 1987;198(1):129-32.
1987: Ascenzi P; Menegatti E; Guarneri M; Amiconi G
Active-site titration of serine proteinases acting selectively on cationic substrates by N-alpha-carbobenzoxy-L-arginine p-nitrophenyl ester and N-alpha-carbobenzoxy-L-lysine p-nitrophenyl ester; determination of active enzyme concentration.
Biochimica et biophysica acta 1987;915(3):421-5.
1987: Ascenzi P; Aducci P; Torroni A; Amiconi G; Ballio A; Menegatti E; Guarneri M
The pH dependence of pre-steady-state and steady-state kinetics for the papain-catalyzed hydrolysis of N-alpha-carbobenzoxyglycine p-nitrophenyl ester.
Biochimica et biophysica acta 1987;912(2):203-10.
1987: Ascenzi P; Amiconi G; Bolognesi M; Menegatti E; Guarneri M
Binding of the Ile-Val and Val-Val effector dipeptides to the binary adducts of bovine trypsinogen with Kunitz and Kazal inhibitors as well as the acylating agent p-nitrophenyl p-guanidinobenzoate. A thermodynamic and kinetic study.
Journal of molecular biology 1987;194(4):751-4.
1987: Menegatti E; Boggian M; Ascenzi P; Luisi P L
Binding of the trypsin inhibitor from white mustard (Sinapis alba L.) seeds to bovine beta-trypsin: thermodynamic study.
Journal of enzyme inhibition 1987;2(1):67-71.
1987: Menegatti E; Ferroni R; Scalia S; Guarneri M; Bolognesi M; Ascenzi P; Amiconi G
Inhibition of serine proteinases by tetra-p-amidinophenoxy-neo-pentane: thermodynamic and molecular modeling study.
Journal of enzyme inhibition 1987;2(1):23-30.
1986: Ferroni R; Menegatti E; Orlandini P; Guarneri M; Taddeo U; Bolognesi M; Ascenzi P; Bertollini A; Amiconi G
Aromatic tetra-amidines: antiproteolytic and antiesterolytic activities towards serine proteinases involved in blood coagulation and clot lysis.
Il Farmaco; edizione scientifica 1986;41(6):464-70.
1986: Ascenzi P; Bertollini A; Bolognesi M; Guarneri M; Menegatti E; Amiconi G
Primary specificity of ancrod, the coagulating serine proteinase from the Malayan pit viper (Agkistrodon rhodostoma) venom.
Biochimica et biophysica acta 1986;871(2):225-8.
1985: Ferroni R; Menegatti E; Orlandini P; Scalia S; Guarneri M; Bolognesi M; Ascenzi P
Ethyl esters of N-(3- and N-(4-amidinobenzoyl)(-L-)amino acids: synthesis and antiproteolytic activity towards bovine trypsin and porcine pancreatic kallikrein.
Il Farmaco; edizione scientifica 1985;40(10):717-29.
1985: Ascenzi P; Bertollini A; Bolognesi M; Guarneri M; Menegatti E; Amiconi G
Catalytic properties of Ancrod, the thrombin-like proteinase from the Malayan pit viper (Agkistrodon rhodostoma) venom.
Biochimica et biophysica acta 1985;829(3):415-23.
1985: Menegatti E; Scalia S; Bortolotti F; Ascenzi P; De Marco A; Guarneri M
Simultaneous determination of gabexate mesilate (Foy) and its catabolite in plasma and whole blood by reverse-phase high-performance liquid chromatography.
Pharmaceutica acta Helvetiae 1985;60(5-6):170-4.
1984: Ferroni R; Menegatti E; Guarneri M; Taddeo U; Bolognesi M; Ascenzi P; Amiconi G
Aromatic tetra-amidines: synthesis of halo-derivatives and their antiproteolytic activity.
Il Farmaco; edizione scientifica 1984;39(11):901-9.

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