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Manzour Hernando Hazbón

Research Profile

Living Beings

Chemicals & Drugs

Procedures

Physiology

Genes & Molecular Sequences

Disorders

Multidrug-Resistant Tuberculosis

Concepts & Ideas

Sensitivity and Specificity

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Publications

TOP 3
Cicely Washington; David Metzgar; Manzour Hernando Hazbón; Leonard Binn; Arthur Lyons; Carl Coward; Robert Kuschner
Multiplexed Luminex xMAP assay for detection and identification of five adenovirus serotypes associated with epidemics of respiratory disease in adults.
Catherine Vilchèze; Yossef Av-Gay; Rodgoun Attarian; Zhen Liu; Manzour Hernando Hazbón; Roberto Colangeli; Bing Chen; Weijun Liu; David Alland; James C Sacchettini; William R. Jacobs Jr.
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
Manzour Hernando Hazbón; Alifiya Motiwala; Magali Cavatore; Michael Brimacombe; Thomas S Whittam; David Alland
Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis.

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All Publications

2010: Cicely Washington; David Metzgar; Manzour Hernando Hazbón; Leonard Binn; Arthur Lyons; Carl Coward; Robert Kuschner
Multiplexed Luminex xMAP assay for detection and identification of five adenovirus serotypes associated with epidemics of respiratory disease in adults.
Journal of clinical microbiology 2010;48(6):2217-22.
2008: Catherine Vilchèze; Yossef Av-Gay; Rodgoun Attarian; Zhen Liu; Manzour Hernando Hazbón; Roberto Colangeli; Bing Chen; Weijun Liu; David Alland; James C Sacchettini; William R. Jacobs Jr.
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis.
Molecular microbiology 2008;69(5):1316-29.
2008: Manzour Hernando Hazbón; Alifiya Motiwala; Magali Cavatore; Michael Brimacombe; Thomas S Whittam; David Alland
Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2008;52(9):3369-76.
2008: Hassan Safi; Brendan Sayers; Manzour Hernando Hazbón; David Alland
Transfer of embB codon 306 mutations into clinical Mycobacterium tuberculosis strains alters susceptibility to ethambutol, isoniazid, and rifampin.
Antimicrobial agents and chemotherapy 2008;52(6):2027-34.
2007: Roberto Colangeli; danica helb; Catherine Vilchèze; Manzour Hernando Hazbón; Chee-Gun Lee; Hassan Safi; Brendan Sayers; Irene Sardone; Marcus B Jones; Robert D Fleischmann; Scott N Peterson; William R. Jacobs Jr.; David Alland
Transcriptional regulation of multi-drug tolerance and antibiotic-induced responses by the histone-like protein Lsr2 in M. tuberculosis.
PLoS pathogens 2007;3(6):e87.
2007: David Alland; David W Lacher; Manzour Hernando Hazbón; Alifiya Motiwala; Weihong Qi; Robert D Fleischmann; Thomas S Whittam
Role of large sequence polymorphisms (LSPs) in generating genomic diversity among clinical isolates of Mycobacterium tuberculosis and the utility of LSPs in phylogenetic analysis.
Journal of clinical microbiology 2007;45(1):39-46.
2006: Catherine Vilchèze; Feng Wang; Masayoshi Arai; Manzour Hernando Hazbón; Roberto Colangeli; Laurent Kremer; Torin R Weisbrod; David Alland; James C Sacchettini; William R. Jacobs Jr.
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid.
Nature medicine 2006;12(9):1027-9.
2006: Manzour Hernando Hazbón; Michael Brimacombe; Miriam Bobadilla Del Valle; Magali Cavatore; martha guerrero; Mandira Varma-Basil; Helen Billman-Jacobe; Caroline J Lavender; Janet Fyfe; Lourdes García-García; Clara Inés León; Mridula Bose; Fernando Chaves; Megan Murray; Kathleen D Eisenach; José Sifuentes-Osornio; M Donald Cave; Alfredo Ponce-De-León; David Alland
Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis.
Antimicrobial agents and chemotherapy 2006;50(8):2640-9.
2006: Meliza T Talaue; VISHWANATH VENKETARAMAN; Manzour Hernando Hazbón; Marcy A Peteroy-Kelly; Anjali Seth; Roberto Colangeli; David Alland; Nancy Connell
Arginine homeostasis in J774.1 macrophages in the context of Mycobacterium bovis BCG infection.
Journal of bacteriology 2006;188(13):4830-40.
2006: Ingrid Filliol; Alifiya Motiwala; Magali Cavatore; Weihong Qi; Manzour Hernando Hazbón; Miriam Bobadilla Del Valle; Janet Fyfe; Lourdes García-García; Nalin Rastogi; Christophe Sola; Thierry Zozio; martha guerrero; Clara Inés León; Jonathan Crabtree; Samuel V Angiuoli; Kathleen D Eisenach; Riza Durmaz; Moses L Joloba; Adrian Rendón; José Sifuentes-Osornio; Alfredo Ponce-De-León; M Donald Cave; Robert D Fleischmann; Thomas S Whittam; David Alland
Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set.
Journal of bacteriology 2006;188(2):759-72.
2005: Manzour Hernando Hazbón; Miriam Bobadilla Del Valle; martha guerrero; Mandira Varma-Basil; Ingrid Filliol; Magali Cavatore; Roberto Colangeli; Hassan Safi; Helen Billman-Jacobe; Caroline J Lavender; Janet Fyfe; Lourdes García-García; Amy Davidow; Michael Brimacombe; Clara Inés León; Tania Porras; Mridula Bose; Fernando Chaves; Kathleen D Eisenach; José Sifuentes-Osornio; Alfredo Ponce-De-León; M Donald Cave; David Alland
Role of embB codon 306 mutations in Mycobacterium tuberculosis revisited: a novel association with broad drug resistance and IS6110 clustering rather than ethambutol resistance.
Antimicrobial agents and chemotherapy 2005;49(9):3794-802.
2005: Roberto Colangeli; danica helb; sudharsan sridharan; Jingchuan Sun; Mandira Varma-Basil; Manzour Hernando Hazbón; Ryhor Harbacheuski; Nicholas J Megjugorac; William R. Jacobs Jr.; Andreas Holzenburg; James C Sacchettini; David Alland
The Mycobacterium tuberculosis iniA gene is essential for activity of an efflux pump that confers drug tolerance to both isoniazid and ethambutol.
Molecular microbiology 2005;55(6):1829-40.
2005: Catherine Vilchèze; Torin R Weisbrod; Bing Chen; Laurent Kremer; Manzour Hernando Hazbón; Feng Wang; David Alland; James C Sacchettini; William R. Jacobs Jr.
Altered NADH/NAD+ ratio mediates coresistance to isoniazid and ethionamide in mycobacteria.
Antimicrobial agents and chemotherapy 2005;49(2):708-20.
2005: Nancy G Saravia; Manzour Hernando Hazbón; Elvia osorio; Liliana Valderrama; John Walker; C Santrich; Tania M Cortázar; Jonathan H LeBowitz; bruno travi
Protective immunogenicity of the paraflagellar rod protein 2 of Leishmania mexicana.
Vaccine 2005;23(8):984-95.
2004: Mandira Varma-Basil; Hiyam El-Hajj; Roberto Colangeli; Manzour Hernando Hazbón; Sujeet Kumar; Mridula Bose; Miriam Bobadilla Del Valle; Lourdes García García; Araceli Hernández; Fred Kramer; Jose Sifuentes Osornio; Alfredo Ponce-De-León; David Alland
Rapid detection of rifampin resistance in Mycobacterium tuberculosis isolates from India and Mexico by a molecular beacon assay.
Journal of clinical microbiology 2004;42(12):5512-6.
2004: Michele Boniotto; Manzour Hernando Hazbón; William J Jordan; Greig P Lennon; Joyce Eskdale; David Alland; Grant Gallagher
Novel hairpin-shaped primer assay to study the association of the -44 single-nucleotide polymorphism of the DEFB1 gene with early-onset periodontal disease.
Clinical and diagnostic laboratory immunology 2004;11(4):766-9.
2004: Manzour Hernando Hazbón
Recent advances in molecular methods for early diagnosis of tuberculosis and drug-resistant tuberculosis.
Biomédica : revista del Instituto Nacional de Salud 2004;24 Supp 1():149-62.
2004: Mandira Varma-Basil; Hiyam El-Hajj; Salvatore A E Marras; Manzour Hernando Hazbón; Jessica M Mann; Nancy Connell; Fred Kramer; David Alland
Molecular beacons for multiplex detection of four bacterial bioterrorism agents.
Clinical chemistry 2004;50(6):1060-2.
2004: Manzour Hernando Hazbón; David Alland
Hairpin primers for simplified single-nucleotide polymorphism analysis of Mycobacterium tuberculosis and other organisms.
Journal of clinical microbiology 2004;42(3):1236-42.
2003: Manzour Hernando Hazbón; Nora Guarín; Beatriz Eugenia Ferro; Ana Lucía Rodríguez; Luz Angela Labrada; Rafael Tovar; Paul F Riska; William R. Jacobs Jr.
Photographic and luminometric detection of luciferase reporter phages for drug susceptibility testing of clinical Mycobacterium tuberculosis isolates.
Journal of clinical microbiology 2003;41(10):4865-9.
2000: Manzour Hernando Hazbón; M del Socorro Orozco; Luz Angela Labrada; Rafael Tovar; Kristen A Weigle; A Wanger
Evaluation of Etest for susceptibility testing of multidrug-resistant isolates of Mycobacterium tuberculosis.
Journal of clinical microbiology 2000;38(12):4599-603.