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Chuan He

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Chun-Xiao Song; Craig Street; Keith E Szulwach; Hao Wu; Guo-Liang Xu; Qing Dai; Ye Fu; Juan Gao; Peng Jin; Lin Li; Yujing Li; Li Lin; Peng Liu; Shi-Qing Mao; Mickael Poidevin; Chuan He
Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming.
Quanjiang Ji; Marcus B Jones; Lefu Lan; Haihua Liang; Scott N Peterson; Fei Sun; Liang Zhang; Taeok Bae; Pedro Brugarolas; Hoonsik Cho; Xin Deng; Yihe N Gao; Chuan He
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Xin Deng; Ye Fu; Sophie Alvarez; Benjamin F Cravatt; Leslie M Hicks; Quanjiang Ji; Lefu Lan; Jiaxin Li; Haihua Liang; Fei Sun; Olesya Ulanovskaya; Chu Wang; Eranthie Weerapana; Min Wu; Yan Ye; Haiyan Zhang; Lu Zhou; Chuan He
Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.

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All Publications

2013: Chun-Xiao Song; Craig Street; Keith E Szulwach; Hao Wu; Guo-Liang Xu; Qing Dai; Ye Fu; Juan Gao; Peng Jin; Lin Li; Yujing Li; Li Lin; Peng Liu; Shi-Qing Mao; Mickael Poidevin; Chuan He
Genome-wide Profiling of 5-Formylcytosine Reveals Its Roles in Epigenetic Priming.
Cell 2013;153(3):678-91.
2013: Quanjiang Ji; Marcus B Jones; Lefu Lan; Haihua Liang; Scott N Peterson; Fei Sun; Liang Zhang; Taeok Bae; Pedro Brugarolas; Hoonsik Cho; Xin Deng; Yihe N Gao; Chuan He
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(13):5010-5.
2013: Xin Deng; Ye Fu; Sophie Alvarez; Benjamin F Cravatt; Leslie M Hicks; Quanjiang Ji; Lefu Lan; Jiaxin Li; Haihua Liang; Fei Sun; Olesya Ulanovskaya; Chu Wang; Eranthie Weerapana; Min Wu; Yan Ye; Haiyan Zhang; Lu Zhou; Chuan He
Proteome-wide quantification and characterization of oxidation-sensitive cysteines in pathogenic bacteria.
Cell host & microbe 2013;13(3):358-70.
2013: Jun Liu; Seraphine V Wegner; Peng R Chen; Jason Karpus; Chuan He
Genetically encoded copper(I) reporters with improved response for use in imaging.
Journal of the American Chemical Society 2013;135(8):3144-9.
2013: Haihua Liang; Mike Bosscher; Xin Deng; Mark P Jensen; Quanjiang Ji; Chuan He
Engineering bacterial two-component system PmrA/PmrB to sense lanthanide ions.
Journal of the American Chemical Society 2013;135(6):2037-9.
2013: Guifang Jia; Ye Fu; Chuan He
Reversible RNA adenosine methylation in biological regulation.
Trends in genetics : TIG 2013;29(2):108-15.
2013: Guanqun Zheng; Florian Bogdan; Ralph P G Bosmans; John Arne Dahl; Qing Dai; Peter Fedorcsak; Ye Fu; Kari Furu; Ya-Juan Hao; Chun-Min Huang; Guifang Jia; Arne Klungland; Hans E Krokan; Charles J Li; Jun Liu; Zhike Lu; Yamei Niu; Yue Shi; Shu-Hui Song; Wei-Min Tong; Cathrine B Vågbø; Wen-Ling Wang; Xiu-Jie Wang; Xin Yang; Yun-Gui Yang; Wen-Ming Zhao; Xu Zhao; Chuan He
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility.
Molecular cell 2013;49(1):18-29.
2013: Ye Fu; Ke-Li Han; Kathleen A Bailey; Qiang Cui; Qing Dai; Guifang Jia; Charles J Li; Marcelo A Nobrega; Xueqin Pang; Scott Smemo; Richard N Wang; Xiao Wang; Chuan He
FTO-mediated formation of N(6)-hydroxymethyladenosine and N(6)-formyladenosine in mammalian RNA.
Nature communications 2013;4():1798.
2013: Liang Zhang; Qing Dai; Gary C Hon; Peng Jin; Xingyu Lu; Jung-Hyun Min; Beomseok Park; Bing Ren; Chun-Xiao Song; Craig R Street; Keith E Szulwach; Huiping Tan; Xiao Wang; Miao Yu; Chuan He
Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing.
Nature communications 2013;4():1517.
2013: Chengqi Yi; Chuan He
DNA repair by reversal of DNA damage.
Cold Spring Harbor perspectives in biology 2013;5(1):a012575.
2012: Miao Yu; Gary C Hon; Peng Jin; Bing Ren; Chun-Xiao Song; Keith E Szulwach; Chuan He
Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine.
Nature protocols 2012;7(12):2159-70.
2012: Ye Fu; Chuan He
Nucleic acid modifications with epigenetic significance.
Current opinion in chemical biology 2012;16(5-6):516-24.
2012: Pedro Brugarolas; Scott G Franzblau; Yihe N Gao; Farahnaz Movahedzadeh; Martin I Voskuil; Yuehong Wang; Nan Zhang; Iona L Bartek; Chuan He
The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis.
The Journal of biological chemistry 2012;287(45):37703-12.
2012: Chun-Xiao Song; Chengqi Yi; Chuan He
Mapping recently identified nucleotide variants in the genome and transcriptome.
Nature biotechnology 2012;30(11):1107-16.
2012: Xi Jiang; Rejani B Kunjamma; Richard A Larson; Michelle M Le Beau; Yuanyuan Li; Zejuan Li; Paul P Liu; Jun Lu; Jonathan M Matthews; Mary Beth Neilly; Colles Price; Haomin Ren; Robert K Slany; Jinhua Wang; Xiao Wang; Mengyi Xu; Dewen You; Jiwang Zhang; Shuodan Zhang; Ping Chen; Abdel Elkahloun; Sandeep Gurbuxani; Chuan He; Chunjiang He; Gia-Ming Hong; Hao Huang; Stephen Arnovitz; Jianjun Chen
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia.
Cancer cell 2012;22(4):524-35.
2012: Fei Sun; Catherine C L Wong; Sherrie Xie; Chengqi Yi; Liang Zhang; Sophie Alvarez; Xin Deng; Yue Ding; Leslie M Hicks; Quanjiang Ji; Hualiang Jiang; Lefu Lan; Zhongjie Liang; Cheng Luo; Chuan He
Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(38):15461-6.
2012: Jing Wang; Boxuan Simen Zhao; Peng R Chen; Jason Karpus; Zheng Luo; Chuan He
A selective fluorescent probe for carbon monoxide imaging in living cells.
Angewandte Chemie (International ed. in English) 2012;51(38):9652-6.
2012: Yandong Yin; Chuan He; Xun Li; Peng Wang; Xin Xing Yang; Xin Sheng Zhao
Panorama of DNA hairpin folding observed via diffusion-decelerated fluorescence correlation spectroscopy.
Chemical communications (Cambridge, England) 2012;48(59):7413-5.
2012: Chengqi Yi; Liang Zhang; Wen Zhang; Baoen Chen; Aaron R Dinner; Guifang Jia; Charles J Li; Bo Qi; Cai-Guang Yang; Chuan He
Duplex interrogation by a direct DNA repair protein in search of base damage.
Nature structural & molecular biology 2012;19(7):671-6.
2012: Quanjiang Ji; Haihua Liang; Fei Sun; Liang Zhang; Taeok Bae; Xin Deng; Chuan He
Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response.
The Journal of biological chemistry 2012;287(25):21102-9.
2012: Miao Yu; Liang Zhang; Qing Dai; Gary C Hon; Peng Jin; Audrey Kim; Xuekun Li; Jung-Hyun Min; Beomseok Park; Bing Ren; Yin Shen; Chun-Xiao Song; Keith E Szulwach; Chuan He
Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome.
Cell 2012;149(6):1368-80.
2012: Fei Sun; Sherrie Xie; Haiyan Zhang; Sophie Alvarez; Taeok Bae; Hoonsik Cho; Xin Deng; Leslie M Hicks; Quanjiang Ji; Hualiang Jiang; Xiangqian Kong; Haihua Liang; Cheng Luo; Chuan He
Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(23):9095-100.
2012: Liang Zhang; Qing Dai; Hualiang Jiang; Haihua Liang; Junyan Lu; Xingyu Lu; Cheng Luo; Guo-Liang Xu; Chuan He
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA.
Nature chemical biology 2012;8(4):328-30.
2012: Baikuntha P Aryal; Chuan He; Tatjana Paunesku; Gayle E Woloschak; Mark P Jensen
A proteomic approach to identification of plutonium-binding proteins in mammalian cells.
Journal of proteomics 2012;75(5):1505-14.
2011: Qing Dai; Chuan He
Preparation of DNA containing 5-hydroxymethyl-2'-deoxycytidine modification through phosphoramidites with TBDMS as 5-hydroxymethyl protecting group.
Current protocols in nucleic acid chemistry / edited by Serge L. Beaucage ... [et al.] 2011;Chapter 4():Unit 4.47.1-18.
2011: Guifang Jia; Tomas Lindahl; Tao Pan; Ying Yang; Yun-Gui Yang; Chengqi Yi; Xu Zhao; Guanqun Zheng; Qing Dai; Ye Fu; Chuan He
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO.
Nature chemical biology 2011;7(12):885-7.
2011: David A Capretto; Chad Brouwer; Catherine B Poor; Chuan He
Gold(I)-catalyzed formation of 3-pyrazolines through cycloaddition of diaziridine to alkynes.
Organic letters 2011;13(21):5842-5.
2011: Chun-Xiao Song; Chuan He
The hunt for 5-hydroxymethylcytosine: the sixth base.
Epigenomics 2011;3(5):521-3.
2011: Chun-Xiao Song; Chuan He
Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes.
Accounts of chemical research 2011;44(9):709-17.
2011: Salih Özçubukçu; Seraphine Wegner; Mark P Jensen; Kalyanaswer Mandal; Chuan He
Selective recognition of americium by peptide-based reagents.
Inorganic chemistry 2011;50(17):7937-9.
2011: Chun-Xiao Song; Miao Yu; Qing Dai; Chuan He
Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(α)I.
Bioorganic & medicinal chemistry letters 2011;21(17):5075-7.
2011: Fei Sun; Chengqi Yi; Bing-Chuan Zhao; Lu Zhou; Taeok Bae; Hoonsik Cho; Xin Deng; Xing Jian; Zigang Li; Chi-Hao Luan; Chun-Xiao Song; Chuan He
Targeting MgrA-mediated virulence regulation in Staphylococcus aureus.
Chemistry & biology 2011;18(8):1032-41.
2011: Pedro Brugarolas; Erica M Duguid; Catherine B Poor; Wen Zhang; Chuan He
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus.
Acta crystallographica. Section D, Biological crystallography 2011;67(Pt 8):707-15.
2011: Chun-Xiao Song; Yao Sun; Cai-Guang Yang; Miao Yu; Qing Dai; Xing-Yu Lu; Chuan He
Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage β-glucosyltransferase.
Chembiochem : a European journal of chemical biology 2011;12(11):1682-5.
2011: Qing Dai; Chuan He
Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA.
Organic letters 2011;13(13):3446-9.
2011: Qing Dai; Chun-Xiao Song; Tao Pan; Chuan He
Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA.
The Journal of organic chemistry 2011;76(10):4182-8.
2011: Peng R Chen; Pedro Brugarolas; Chuan He
Redox signaling in human pathogens.
Antioxidants & redox signaling 2011;14(6):1107-18.
2011: Seraphine V Wegner; Fei Sun; Nick Hernandez; Chuan He
The tightly regulated copper window in yeast.
Chemical communications (Cambridge, England) 2011;47(9):2571-3.
2011: Chun-Xiao Song; Keith E Szulwach; Ye Fu; Qing Dai; Chengqi Yi; Xuekun Li; Yujing Li; Chih-Hsin Chen; Wen Zhang; Xing Jian; Jing Wang; Li Zhang; Timothy J Looney; Baichen Zhang; Lucy A Godley; Leslie M Hicks; Bruce T Lahn; Peng Jin; Chuan He
Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine.
Nature biotechnology 2011;29(1):68-72.
2010: Chuan He
Grand challenge commentary: RNA epigenetics?
Nature chemical biology 2010;6(12):863-5.
2010: Ye Fu; Qing Dai; Wen Zhang; Jin Ren; Tao Pan; Chuan He
The AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNA.
Angewandte Chemie (International ed. in English) 2010;49(47):8885-8.
2010: Chengqi Yi; Guifang Jia; Guanhua Hou; Qing Dai; Wen Zhang; Guanqun Zheng; Xing Jian; Cai-Guang Yang; Qiang Cui; Chuan He
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase.
Nature 2010;468(7321):330-3.
2010: Lianghua Lu; Chengqi Yi; Xing Jian; Guanqun Zheng; Chuan He
Structure determination of DNA methylation lesions N1-meA and N3-meC in duplex DNA using a cross-linked protein-DNA system.
Nucleic acids research 2010;38(13):4415-25.
2010: Lefu Lan; Alice Cheng; Paul Dunman; Dominique M Missiakas; Chuan He
Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
Journal of bacteriology 2010;192(12):3068-77.
2010: Seraphine V Wegner; Hasan Arslan; Murat Sunbul; Jun Yin; Chuan He
Dynamic copper(I) imaging in mammalian cells with a genetically encoded fluorescent copper(I) sensor.
Journal of the American Chemical Society 2010;132(8):2567-9.
2010: Fei Sun; Hoonsik Cho; Do-Won Jeong; Chunling Li; Chuan He; Taeok Bae
Aureusimines in Staphylococcus aureus are not involved in virulence.
PloS one 2010;5(12):e15703.
2010: Lefu Lan; Thomas S Murray; Barbara I Kazmierczak; Chuan He
Pseudomonas aeruginosa OspR is an oxidative stress sensing regulator that affects pigment production, antibiotic resistance and dissemination during infection.
Molecular microbiology 2010;75(1):76-91.
2009: Jonathan M Budzik; Catherine B Poor; Kym F Faull; Julian P Whitelegge; Chuan He; Olaf Schneewind
Intramolecular amide bonds stabilize pili on the surface of bacilli.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):19992-7.
2009: Catherine B Poor; Peng R Chen; Erica Duguid; Phoebe A Rice; Chuan He
Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus.
The Journal of biological chemistry 2009;284(35):23517-24.
2009: Xing Jian; Erik C Wasinger; Jenny V Lockard; Lin X Chen; Chuan He
Highly sensitive and selective gold(I) recognition by a metalloregulator in Ralstonia metallidurans.
Journal of the American Chemical Society 2009;131(31):10869-71.
2009: Chengqi Yi; Cai-Guang Yang; Chuan He
A non-heme iron-mediated chemical demethylation in DNA and RNA.
Accounts of chemical research 2009;42(4):519-29.
2009: Yihan Lin; Tong Zhao; Xing Jian; Zishaan Farooqui; Xiaohui Qu; Chuan He; Aaron R Dinner; Norbert F Scherer
Using the bias from flow to elucidate single DNA repair protein sliding and interactions with DNA.
Biophysical journal 2009;96(5):1911-7.
2009: Cai-Guang Yang; Kristel Garcia; Chuan He
Damage detection and base flipping in direct DNA alkylation repair.
Chembiochem : a European journal of chemical biology 2009;10(3):417-23.
2009: Chuan He
Chemical methods to study protein-nucleic acid interactions.
Nucleic acids symposium series (2004) 2009;(53):43.
2009: Shangdong Yang; Zigang Li; Xing Jian; Chuan He
Platinum(II)-catalyzed intramolecular cyclization of o-substituted aryl alkynes through sp3 C-H activation.
Angewandte Chemie (International ed. in English) 2009;48(22):3999-4001.
2009: Seraphine V Wegner; Hande Boyaci; Hao Chen; Mark P Jensen; Chuan He
Engineering a uranyl-specific binding protein from NikR.
Angewandte Chemie (International ed. in English) 2009;48(13):2339-41.
2009: Stefan Richter; Valerie J Anderson; Gabriella Garufi; Lianghua Lu; Jonathan M Budzik; Andrzej Joachimiak; Chuan He; Olaf Schneewind; Dominique M Missiakas
Capsule anchoring in Bacillus anthracis occurs by a transpeptidation reaction that is inhibited by capsidin.
Molecular microbiology 2009;71(2):404-20.
2009: Peng R Chen; Satoshi Nishida; Catherine B Poor; Alice Cheng; Taeok Bae; Lisa Kuechenmeister; Paul Dunman; Dominique M Missiakas; Chuan He
A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
Molecular microbiology 2009;71(1):198-211.
2008: Uddhav Kumar Shigdel; Chuan He
A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT).
Journal of the American Chemical Society 2008;130(52):17634-5.
2008: Guifang Jia; Cai-Guang Yang; Shangdong Yang; Xing Jian; Chengqi Yi; Zhiqiang Zhou; Chuan He
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO.
FEBS letters 2008;582(23-24):3313-9.
2008: Hao Chen; Jie Hu; Peng R Chen; Lefu Lan; Zigang Li; Leslie M Hicks; Aaron R Dinner; Chuan He
The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13586-91.
2008: Cai-Guang Yang; Chengqi Yi; Erica M Duguid; Christopher T Sullivan; Xing Jian; Phoebe A Rice; Chuan He
Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Nature 2008;452(7190):961-5.
2008: Peng R Chen; Chuan He
Selective recognition of metal ions by metalloregulatory proteins.
Current opinion in chemical biology 2008;12(2):214-21.
2008: Uddhav Kumar Shigdel; Junliang Zhang; Chuan He
Diazirine-based DNA photo-cross-linking probes for the study of protein-DNA interactions.
Angewandte Chemie (International ed. in English) 2008;47(1):90-3.
2007: Thomas Durek; Junliang Zhang; Chuan He; Stephen B H Kent
Synthesis of photoactive analogues of a cystine knot trypsin inhibitor protein.
Organic letters 2007;9(26):5497-500.
2007: Peng R Chen; Erik C Wasinger; Jing Zhao; Daniel van der Lelie; Lin X Chen; Chuan He
Spectroscopic insights into lead(II) coordination by the selective lead(II)-binding protein PbrR691.
Journal of the American Chemical Society 2007;129(41):12350-1.
2007: Susanta K Sarkar; Nesha May Andoy; Jaime J Benítez; Peng R Chen; Jason S Kong; Chuan He; Peng Chen
Engineered holliday junctions as single-molecule reporters for protein-DNA interactions with application to a MerR-family regulator.
Journal of the American Chemical Society 2007;129(41):12461-7.
2007: Zigang Li; David A Capretto; Ronald O Rahaman; Chuan He
Gold(III)-catalyzed nitrene insertion into aromatic and benzylic C-H groups.
Journal of the American Chemical Society 2007;129(40):12058-9.
2007: Seraphine V Wegner; Ayse Okesli; Peng Chen; Chuan He
Design of an emission ratiometric biosensor from MerR family proteins: a sensitive and selective sensor for Hg2+.
Journal of the American Chemical Society 2007;129(12):3474-5.
2007: Zigang Li; D A Capretto; R Rahaman; Chuan He
Silver-catalyzed intermolecular amination of C--H groups.
Angewandte Chemie (International ed. in English) 2007;46(27):5184-6.
2006: Peng R Chen; Taeok Bae; Wade A Williams; Erica M Duguid; Phoebe A Rice; Olaf Schneewind; Chuan He
An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus.
Nature chemical biology 2006;2(11):591-5.
2006: Zigang Li; Junliang Zhang; Chad Brouwer; Cai-Guang Yang; Nicholas W Reich; Chuan He
Brønsted acid catalyzed addition of phenols, carboxylic acids, and tosylamides to simple olefins.
Organic letters 2006;8(19):4175-8.
2006: Zigang Li; Xiangyu Ding; Chuan He
Nitrene transfer reactions catalyzed by gold complexes.
The Journal of organic chemistry 2006;71(16):5876-80.
2006: Yukiko Mishina; Chuan He
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins.
Journal of inorganic biochemistry 2006;100(4):670-8.
2006: Chad Brouwer; Chuan He
Efficient gold-catalyzed hydroamination of 1,3-dienes.
Angewandte Chemie (International ed. in English) 2006;45(11):1744-7.
2006: Junliang Zhang; Cai-Guang Yang; Chuan He
Gold(I)-catalyzed intra- and intermolecular hydroamination of unactivated olefins.
Journal of the American Chemical Society 2006;128(6):1798-9.
2006: Yukiko Mishina; Erica M Duguid; Chuan He
Direct reversal of DNA alkylation damage.
Chemical reviews 2006;106(2):215-32.
2005: Yukiko Mishina; Cai-Guang Yang; Chuan He
Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.
Journal of the American Chemical Society 2005;127(42):14594-5.
2005: Cai-Guang Yang; Nicholas W Reich; Zhangjie Shi; Chuan He
Intramolecular additions of alcohols and carboxylic acids to inert olefins catalyzed by silver(I) triflate.
Organic letters 2005;7(21):4553-6.
2005: Chuan He; Jean-Christophe Hus; Li Jing Sun; Pei Zhou; Derek P G Norman; Volker Dötsch; Hua Wei; John D Gross; William Stratton Lane; Gerhard Wagner; Gregory L Verdine
A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
Molecular cell 2005;20(1):117-29.
2005: Erica M Duguid; Phoebe A Rice; Chuan He
The structure of the human AGT protein bound to DNA and its implications for damage detection.
Journal of molecular biology 2005;350(4):657-66.
2005: Cai-Guang Yang; Chuan He
Gold(I)-catalyzed intermolecular addition of phenols and carboxylic acids to olefins.
Journal of the American Chemical Society 2005;127(19):6966-7.
2005: Peng Chen; Bill Greenberg; Safiyh Taghavi; Christine Romano; Daniel van der Lelie; Chuan He
An exceptionally selective lead(II)-regulatory protein from Ralstonia metallidurans: development of a fluorescent lead(II) probe.
Angewandte Chemie (International ed. in English) 2005;44(18):2715-9.
2004: Yukiko Mishina; Lin X Chen; Chuan He
Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli.
Journal of the American Chemical Society 2004;126(51):16930-6.
2004: Zhangjie Shi; Chuan He
Direct functionalization of arenes by primary alcohol sulfonate esters catalyzed by gold(III).
Journal of the American Chemical Society 2004;126(42):13596-7.
2004: Yong Cui; Chuan He
A silver-catalyzed intramolecular amidation of saturated C--h bonds.
Angewandte Chemie (International ed. in English) 2004;43(32):4210-2.
2004: Zhangjie Shi; Chuan He
Efficient functionalization of aromatic C-H bonds catalyzed by gold(III) under mild and solvent-free conditions.
The Journal of organic chemistry 2004;69(11):3669-71.
2004: Zhangjie Shi; Chuan He
An Au-catalyzed cyclialkylation of electron-rich arenes with epoxides to prepare 3-chromanols.
Journal of the American Chemical Society 2004;126(19):5964-5.
2004: Chuan He; Yukiko Mishina
Modeling non-heme iron proteins.
Current opinion in chemical biology 2004;8(2):201-8.
2004: Peng Chen; Chuan He
A general strategy to convert the MerR family proteins into highly sensitive and selective fluorescent biosensors for metal ions.
Journal of the American Chemical Society 2004;126(3):728-9.
2004: Yukiko Mishina; Chih-Hui J Lee; Chuan He
Interaction of human and bacterial AlkB proteins with DNA as probed through chemical cross-linking studies.
Nucleic acids research 2004;32(4):1548-54.
2003: Yong Cui; Chuan He
Efficient aziridination of olefins catalyzed by a unique disilver(I) compound.
Journal of the American Chemical Society 2003;125(52):16202-3.
2003: Erica M Duguid; Yukiko Mishina; Chuan He
How do DNA repair proteins locate potential base lesions? a chemical crosslinking method to investigate O6-alkylguanine-DNA alkyltransferases.
Chemistry & biology 2003;10(9):827-35.
2003: Yukiko Mishina; Chuan He
Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.
Journal of the American Chemical Society 2003;125(29):8730-1.
2003: Chuan He; Hua Wei; Gregory L Verdine
Converting the sacrificial DNA repair protein N-ada into a catalytic methyl phosphotriester repair enzyme.
Journal of the American Chemical Society 2003;125(6):1450-1.
2002: Chuan He; Gregory L Verdine
Trapping distinct structural states of a protein/DNA interaction through disulfide crosslinking.
Chemistry & biology 2002;9(12):1297-303.