FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Michael Aschner

Research Profile

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Physiology

Biological Transport

Concepts & Ideas

Drug Dose Response Relationship

Co-author Network

Publications

TOP 3
Nathalie L Maitre; Judy L Aschner; Michael Aschner
Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired spatial cognition in neonatal piglets.
Dinamene Santos; Michael Aschner; M Camila Batoreu; Ana P Marreilha dos Santos
Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity.
Marcelo Farina; Daiana Silva Avila; João Batista Teixeira da Rocha; Michael Aschner
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Michael Aschner (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Nathalie L Maitre; Judy L Aschner; Michael Aschner
Manganese neurotoxicity may underlie the association between early life iron deficiency and impaired spatial cognition in neonatal piglets.
The Journal of nutrition 2013;143(4):548.
2013: Dinamene Santos; Michael Aschner; M Camila Batoreu; Ana P Marreilha dos Santos
Comparison between 5-aminosalicylic acid (5-ASA) and para-aminosalicylic acid (4-PAS) as potential protectors against Mn-induced neurotoxicity.
Biological trace element research 2013;152(1):113-6.
2013: Marcelo Farina; Daiana Silva Avila; João Batista Teixeira da Rocha; Michael Aschner
Metals, oxidative stress and neurodegeneration: a focus on iron, manganese and mercury.
Neurochemistry international 2013;62(5):575-94.
2013: Eunsook Lee; Joao B T Rocha; Marta Sidoryk-Wegrzynowicz; Marcelo Farina; Michael Aschner
Estrogen attenuates manganese-induced glutamate transporter impairment in rat primary astrocytes.
Neurotoxicity research 2013;23(2):124-30.
2013: Marta Sidoryk-Wegrzynowicz; Michael Aschner
Role of astrocytes in manganese mediated neurotoxicity.
BMC pharmacology & toxicology 2013;14():23.
2013: Kevin K Kumar; Devin K Patel; Asad A Aboud; Michael Aschner; Aaron B Bowman
Optimization of fluorescence assay of cellular manganese status for high throughput screening.
Journal of biochemical and molecular toxicology 2013;27(1):42-9.
2012: Dinamene Santos; M Sidoryk-Wegrzynowicz; Ruben Ramos; Isabel Almeida; Michael Aschner; M Camila Batoreu; A P Marreilha dos Santos
Manganese alters rat brain amino acids levels.
Biological trace element research 2012;150(1-3):337-41.
2012: Bruna Comparsi; Alcir L Dafre; Alessandro de Souza Prestes; Danúbia B dos Santos; Marcelo Farina; Jeferson Luis Franco; Daiane F Meinerz; Thaís Posser; Sílvio Terra Stefanello; Caroline Wagner; Michael Aschner; João B T Rocha
Diphenyl ditelluride targets brain selenoproteins in vivo: inhibition of cerebral thioredoxin reductase and glutathione peroxidase in mice after acute exposure.
Molecular and cellular biochemistry 2012;370(1-2):173-82.
2012: Eunsook Lee; Kyuwon Lee; Marta Sidoryk-Wêgrzynowicz; Deok-Soo Son; Ning Wang; Anton Webb; Michael Aschner
GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes.
The Journal of biological chemistry 2012;287(32):26817-28.
2012: Candice D Fike; Mark R Kaplowitz; Lawrence S Prince; Marta Sidoryk-Wegrzynowicz; Marshall Summar; Yongmei Zhang; Michael Aschner; Gary Cunningham; Judy L Aschner
Prolonged hypoxia augments L-citrulline transport by system A in the newborn piglet pulmonary circulation.
Cardiovascular research 2012;95(3):375-84.
2012: Eunsook Lee; Marta Sidoryk-Wegrzynowicz; Deok-Soo Son; Anton Webb; Zhaobao Yin; Michael Aschner
Transforming growth factor-α mediates estrogen-induced upregulation of glutamate transporter GLT-1 in rat primary astrocytes.
Glia 2012;60(7):1024-36.
2012: Ebany J Martinez-Finley; Sudipta Chakraborty; Stephanie J B Fretham; Michael Aschner
Cellular transport and homeostasis of essential and nonessential metals.
Metallomics : integrated biometal science 2012;4(7):593-605.
2012: Daiana Silva Avila; Gábor Somlyai; Ildikó Somlyai; Michael Aschner
Anti-aging effects of deuterium depletion on Mn-induced toxicity in a C. elegans model.
Toxicology letters 2012;211(3):319-24.
2012: Michael Aschner
Considerations on methylmercury (MeHg) treatments in in vitro studies.
Neurotoxicology 2012;33(3):512-3.
2012: Sudipta Chakraborty; Michael Aschner
Altered manganese homeostasis: implications for BLI-3-dependent dopaminergic neurodegeneration and SKN-1 protection in C. elegans.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2012;26(2-3):183-7.
2012: Daiana Silva Avila; Alexandre Emmanuel Benedetto; Keith M Erikson; Flávia Manarin; João Batista Teixeira Rocha; Felix Antunes Soares; Catherine Au; Michael Aschner
Organotellurium and organoselenium compounds attenuate Mn-induced toxicity in Caenorhabditis elegans by preventing oxidative stress.
Free radical biology & medicine 2012;52(9):1903-10.
2012: Marta Skowrońska; Luiza Wójcik-Stanaszek; Magdalena Zielińska; Michael Aschner; Dejan Milatovic; Joanna Ruszkiewicz; Jan Albrecht
Ammonia increases paracellular permeability of rat brain endothelial cells by a mechanism encompassing oxidative/nitrosative stress and activation of matrix metalloproteinases.
Journal of neurochemistry 2012;121(1):125-34.
2012: Eunsook Lee; Marta Sidoryk-Węgrzynowicz; Zhaobao Yin; Haiyan Jiang; Michael Aschner
15-Deoxy-Δ12,14-prostaglandin J₂ modulates manganese-induced activation of the NF-κB, Nrf2, and PI3K pathways in astrocytes.
Free radical biology & medicine 2012;52(6):1067-74.
2012: Daiana Avila; Kirsten Helmcke; Michael Aschner
The Caenorhabiditis elegans model as a reliable tool in neurotoxicology.
Human & experimental toxicology 2012;31(3):236-43.
2012: Dinamene Santos; Dejan Milatovic; Vanda Andrade; Michael Aschner; M Camila Batoreu; A P Marreilha dos Santos
The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain.
Toxicology 2012;292(2-3):90-8.
2012: A P Marreilha Dos Santos; Vanda Andrade; Michael Aschner; Rui L Lucas; M Luísa Mateus; Dejan Milatovic; M Camila Batoreu
Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity.
Toxicology and applied pharmacology 2012;258(3):394-402.
2012: João B T Rocha; Michael Aschner; Sandra Ceccatelli; José G Dórea; Marcelo Farina; Luiz Carlos L Silveira
Mercury toxicity.
Journal of biomedicine & biotechnology 2012;2012():831890.
2012: Samuel Caito; Sudipta Chakraborty; Pan Chen; Stephanie Fretham; Ebany Martinez-Finley; Daiana Avila; Michael Aschner
Genome-Wide Analyses of Metal Responsive Genes in Caenorhabditis elegans.
Frontiers in genetics 2012;3():52.
2012: Fabiano M Cordova; Keith M Erikson; Filipe M Gonçalves; Alexandra S Latini; Mark W Lopes; Samantha C Lopes; Tanara V Peres; Célso Pilati; Rui D S Prediger; Aline P Remor; Aderbal S Aguiar; Michael Aschner; Rodrigo B Leal
In vivo manganese exposure modulates Erk, Akt and Darpp-32 in the striatum of developing rats, and impairs their motor function.
PloS one 2012;7(3):e33057.
2012: Jennifer L Madison; Michal Wegrzynowicz; Michael Aschner; Aaron B Bowman
Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism.
PloS one 2012;7(2):e31024.
2011: Aaron B Bowman; Elena Herrero Hernandez; Gunnar F Kwakye; Michael Aschner
Role of manganese in neurodegenerative diseases.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2011;25(4):191-203.
2011: Jennifer L Madison; Michal Wegrzynowicz; Michael Aschner; Aaron B Bowman
Gender and manganese exposure interactions on mouse striatal neuron morphology.
Neurotoxicology 2011;32(6):896-906.
2011: Marta Sidoryk-Wegrzynowicz; Eunsook Lee; Ni Mingwei; Michael Aschner
Disruption of astrocytic glutamine turnover by manganese is mediated by the protein kinase C pathway.
Glia 2011;59(11):1732-43.
2011: Dejan Milatovic; Yingchun Yu; Snjezana Zaja-Milatovic; Ramesh C Gupta; Michael Aschner
Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury.
Toxicology and applied pharmacology 2011;256(3):219-26.
2011: Marcelo Farina; Michael Aschner; João B T Rocha
Oxidative stress in MeHg-induced neurotoxicity.
Toxicology and applied pharmacology 2011;256(3):405-17.
2011: Marcelo Farina; João B T Rocha; Michael Aschner
Mechanisms of methylmercury-induced neurotoxicity: evidence from experimental studies.
Life sciences 2011;89(15-16):555-63.
2011: Dejan Milatovic; Lu Rongzhu; Yingchun Yu; Jonathan E Hood; Jerry W Jenkins; Michael Aschner
Mefloquine neurotoxicity is mediated by non-receptor tyrosine kinase.
Neurotoxicology 2011;32(5):578-85.
2011: Samuel W Caito; Kristina E Hill; Dejan Milatovic; Michael Aschner; Raymond F Burk; William M Valentine
Progression of neurodegeneration and morphologic changes in the brains of juvenile mice with selenoprotein P deleted.
Brain research 2011;1398():1-12.
2011: Dejan Milatovic; Thomas J Montine; Michael Aschner
Prostanoid signaling: dual role for prostaglandin E2 in neurotoxicity.
Neurotoxicology 2011;32(3):312-9.
2011: Zhaobao Yin; Eunsook Lee; Mingwei Ni; Haiyan Jiang; Dejan Milatovic; Lu Rongzhu; Marcelo Farina; Joao B T Rocha; Michael Aschner
Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen.
Neurotoxicology 2011;32(3):291-9.
2011: Mingwei Ni; Xin Li; Zhaobao Yin; Marta Sidoryk-Węgrzynowicz; Haiyan Jiang; Marcelo Farina; Joao B T Rocha; Tore Syversen; Michael Aschner
Comparative study on the response of rat primary astrocytes and microglia to methylmercury toxicity.
Glia 2011;59(5):810-20.
2011: Daniel Henrique Roos; Robson Luiz Puntel; Marcelo Farina; Michael Aschner; Denise Bohrer; João B T Rocha; Nilda B de Vargas Barbosa
Modulation of methylmercury uptake by methionine: prevention of mitochondrial dysfunction in rat liver slices by a mimicry mechanism.
Toxicology and applied pharmacology 2011;252(1):28-35.
2011: A P Marreilha Dos Santos; M Lopes Santos; M Camila C Batoréu; Michael Aschner
Prolactin is a peripheral marker of manganese neurotoxicity.
Brain research 2011;1382():282-90.
2011: Vanessa A Fitsanakis; Na Zhang; Malcolm J Avison; Keith M Erikson; John C Gore; Michael Aschner
Changes in dietary iron exacerbate regional brain manganese accumulation as determined by magnetic resonance imaging.
Toxicological sciences : an official journal of the Society of Toxicology 2011;120(1):146-53.
2011: Parvinder Kaur; Michael Aschner; Tore Syversen
Biochemical factors modulating cellular neurotoxicity of methylmercury.
Journal of toxicology 2011;2011():721987.
2011: Ebany J Martinez-Finley; Michael Aschner
Revelations from the Nematode Caenorhabditis elegans on the Complex Interplay of Metal Toxicological Mechanisms.
Journal of toxicology 2011;2011():895236.
2011: Michael Aschner
Volume measurements in cultured primary astrocytes.
Methods in molecular biology (Clifton, N.J.) 2011;758():391-402.
2011: Dejan Milatovic; Thomas J Montine; Michael Aschner
Measurement of isoprostanes as markers of oxidative stress.
Methods in molecular biology (Clifton, N.J.) 2011;758():195-204.
2011: Marta Sidoryk-Wegrzynowicz; Michal Wegrzynowicz; Eunsook Lee; Aaron B Bowman; Michael Aschner
Role of astrocytes in brain function and disease.
Toxicologic pathology 2011;39(1):115-23.
2011: Daiane Francine Meinerz; Jéssie H Sudati; Danúbia B dos Santos; Andressa Frediani; Eduardo E Alberto; Josiane Allebrandt; Jeferson L Franco; N B V Barbosa; Michael Aschner; João Batista T da Rocha
Evaluation of the biological effects of (S)-dimethyl 2-(3-(phenyltellanyl) propanamido) succinate, a new telluroamino acid derivative of aspartic acid.
Archives of toxicology 2011;85(1):43-9.
2010: Liu Sheng; Xinxin Ding; Marcus Ferguson; Monique McCallister; Raina Rhoades; Mark Maguire; Aramandla Ramesh; Michael Aschner; Daniel Campbell; Pat Levitt; Darryl B Hood
Prenatal polycyclic aromatic hydrocarbon exposure leads to behavioral deficits and downregulation of receptor tyrosine kinase, MET.
Toxicological sciences : an official journal of the Society of Toxicology 2010;118(2):625-34.
2010: Marta Sidoryk-Wegrzynowicz; Eun-Sook Y Lee; Mingwei Ni; Michael Aschner
Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediated proteolytic system.
Glia 2010;58(16):1905-12.
2010: Dejan Milatovic; Thomas J Montine; Snjezana Zaja-Milatovic; Jennifer L Madison; Aaron B Bowman; Michael Aschner
Morphometric analysis in neurodegenerative disorders.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2010;Chapter 12():Unit12.16.
2010: Daniel Henrique Roos; Robson Luiz Puntel; Thiago Henrique Lugokenski; Rafael Porto Ineu; Denise Bohrer; Marilise E Burger; Jeferson Luis Franco; Marcelo Farina; Michael Aschner; João B T Rocha; Nilda B de Vargas Barbosa
Complex methylmercury-cysteine alters mercury accumulation in different tissues of mice.
Basic & clinical pharmacology & toxicology 2010;107(4):789-92.
2010: Parvinder Kaur; Lars Evje; Michael Aschner; Tore Syversen
The in vitro effects of Trolox on methylmercury-induced neurotoxicity.
Toxicology 2010;276(1):73-8.
2010: Yoram Finkelstein; Dejan Milatovic; Philip Lazarovici; Amit Ophir; Elihu D Richter; Michael Aschner; Shimon Lecht; Cezary Marcinkiewicz; Peter Lelkes; Snjezana Zaja-Milatovic; Ramesh C Gupta; Berta Brodsky; Avigail Rosengarten; Elena Proscura; Elena Shapira; Uri Wormser
Peaceful use of disastrous neurotoxicants.
Neurotoxicology 2010;31(5):608-20.
2010: Yoram Finkelstein; Donald A Fox; Michael Aschner; William K Boyes
Gene-environment interactions in neurotoxicology: the 12th biennial meeting of the International Neurotoxicology Association.
Neurotoxicology 2010;31(5):543-4.
2010: Michael Aschner; Edward D Levin; Cristina Suñol; James O Olopade; Kirsten J Helmcke; Daiana S Avila; Damiyon Sledge; Rahim H Ali; Lucia Upchurch; Susan Donerly; Elwood Linney; Anna Forsby; Padmavathi Ponnuru; James R Connor
Gene-environment interactions: neurodegeneration in non-mammals and mammals.
Neurotoxicology 2010;31(5):582-8.
2010: Alexandre Emmanuel Benedetto; Catherine Au; Daiana Silva Avila; Dejan Milatovic; Michael Aschner
Extracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegans.
PLoS genetics 2010;6(8):.
2010: Vanessa A Fitsanakis; Na Zhang; Stephanie Garcia; Michael Aschner
Manganese (Mn) and iron (Fe): interdependency of transport and regulation.
Neurotoxicity research 2010;18(2):124-31.
2010: Michael Aschner; Sandra Ceccatelli
Are neuropathological conditions relevant to ethylmercury exposure?
Neurotoxicity research 2010;18(1):59-68.
2010: Kristina Martinez; Arion Kennedy; Tiffany West; Dejan Milatovic; Michael Aschner; Michael McIntosh
trans-10,cis-12-Conjugated linoleic acid instigates inflammation in human adipocytes compared with preadipocytes.
The Journal of biological chemistry 2010;285(23):17701-12.
2010: Daiana S Avila; Dirleise Colle; Priscila Gubert; Aline S Palma; Gustavo Puntel; Flávia Manarin; Simone Noremberg; Paulo C Nascimento; Michael Aschner; João B T Rocha; Félix A A Soares
A possible neuroprotective action of a vinylic telluride against Mn-induced neurotoxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(1):194-201.
2010: Ana Paula Marreilha dos Santos; Dejan Milatovic; Catherine Au; Zhaobao Yin; Maria Camila C Batoreu; Michael Aschner
Rat brain endothelial cells are a target of manganese toxicity.
Brain research 2010;1326():152-61.
2010: Zhaobao Yin; Haiyan Jiang; Eun-Sook Y Lee; Mingwei Ni; Keith M Erikson; Dejan Milatovic; Aaron B Bowman; Michael Aschner
Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation.
Journal of neurochemistry 2010;112(5):1190-8.
2010: Mingwei Ni; Michael Aschner
Neonatal rat primary microglia: isolation, culturing, and selected applications.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2010;Chapter 12():Unit 12.17.
2010: Dejan Milatovic; Thomas J Montine; Snjezana Zaja-Milatovic; Jennifer L Madison; Aaron B Bowman; Michael Aschner
Morphometric analysis in neurodegenerative disorders.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2010;Chapter 12():Unit 12.16.
2010: Caroline Wagner; Alessandra P Vargas; Daniel H Roos; Carla Porto; Marcelo Farina; Cristina W Nogueira; Michael Aschner; João B Rocha
Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices.
Archives of toxicology 2010;84(2):89-97.
2010: Vernat J Exil; Daiana Silva Avila; Alexandre Emmanuel Benedetto; Elizabeth A Exil; Margaret R Adams; Catherine Au; Michael Aschner
Stressed-induced TMEM135 protein is part of a conserved genetic network involved in fat storage and longevity regulation in Caenorhabditis elegans.
PloS one 2010;5(12):e14228.
2010: Michael Aschner; Natalia Onishchenko; Sandra Ceccatelli
Toxicology of alkylmercury compounds.
Metal ions in life sciences 2010;7():403-34.
2010: B Blairanne Williams; Daphne Li; Michal Wegrzynowicz; Bhavin K Vadodaria; Joel G Anderson; Gunnar F Kwakye; Michael Aschner; Keith M Erikson; Aaron B Bowman
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure.
Journal of neurochemistry 2010;112(1):227-37.
2010: Kirsten J Helmcke; Daiana Silva Avila; Michael Aschner
Utility of Caenorhabditis elegans in high throughput neurotoxicological research.
Neurotoxicology and teratology 2010;32(1):62-7.
2009: Snjezana Zaja-Milatovic; Ramesh C Gupta; Michael Aschner; Dejan Milatovic
Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist.
Toxicology and applied pharmacology 2009;240(2):124-31.
2009: Dejan Milatovic; Snjezana Zaja-Milatovic; Ramesh C Gupta; Yingchun Yu; Michael Aschner
Oxidative damage and neurodegeneration in manganese-induced neurotoxicity.
Toxicology and applied pharmacology 2009;240(2):219-25.
2009: Kirsten J Helmcke; Tore Syversen; David M Miller; Michael Aschner
Characterization of the effects of methylmercury on Caenorhabditis elegans.
Toxicology and applied pharmacology 2009;240(2):265-72.
2009: George C-T Jiang; Sam Hughes; Stephen R Stürzenbaum; Lars Evje; Tore Syversen; Michael Aschner
Caenorhabditis elegans metallothioneins protect against toxicity induced by depleted uranium.
Toxicological sciences : an official journal of the Society of Toxicology 2009;111(2):345-54.
2009: Alexandre Emmanuel Benedetto; Catherine Au; Michael Aschner
Manganese-induced dopaminergic neurodegeneration: insights into mechanisms and genetics shared with Parkinson's disease.
Chemical reviews 2009;109(10):4862-84.
2009: Edward D Levin; Michael Aschner; Ulrike Heberlein; Douglas M Ruden; Kathleen A Welsh-Bohmer; Selena Bartlett; Karen Berger; Lang Chen; Ammon B Corl; Donnie Eddins; Rachael French; Kathleen M Hayden; Kirsten Helmcke; Helmut V B Hirsch; Elwood Linney; Greg Lnenicka; Grier P Page; Debra Possidente; Bernard Possidente; Annette Kirshner
Genetic aspects of behavioral neurotoxicology.
Neurotoxicology 2009;30(5):741-53.
2009: D B Santos; V P P Schiar; Marcio W Paixão; D F Meinerz; Cristina W Nogueira; Michael Aschner; João B T Rocha; N B V Barbosa
Hemolytic and genotoxic evaluation of organochalcogens in human blood cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(6):1195-204.
2009: Marta Sidoryk-Wegrzynowicz; Eun-Sook Y Lee; Jan Albrecht; Michael Aschner
Manganese disrupts astrocyte glutamine transporter expression and function.
Journal of neurochemistry 2009;110(3):822-30.
2009: Gregg D Stanwood; Duncan B Leitch; Valentina Savchenko; Jane Wu; Vanessa A Fitsanakis; Douglas J Anderson; Jeannette N Stankowski; Michael Aschner; BethAnn McLaughlin
Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia.
Journal of neurochemistry 2009;110(1):378-89.
2009: Eun-Sook Y Lee; Marta Sidoryk; Haiyan Jiang; Zhaobao Yin; Michael Aschner
Estrogen and tamoxifen reverse manganese-induced glutamate transporter impairment in astrocytes.
Journal of neurochemistry 2009;110(2):530-44.
2009: Eun-Sook Y Lee; Zhaobao Yin; Dejan Milatovic; Haiyan Jiang; Michael Aschner
Estrogen and tamoxifen protect against Mn-induced toxicity in rat cortical primary cultures of neurons and astrocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2009;110(1):156-67.
2009: D B Santos; V P P Schiar; M C P Ribeiro; R S Schwab; D F Meinerz; J Allebrandt; J B T Rocha; Cristina W Nogueira; Michael Aschner; N B V Barbosa
Genotoxicity of organoselenium compounds in human leukocytes in vitro.
Mutation research 2009;676(1-2):21-6.
2009: Na Zhang; Vanessa A Fitsanakis; Keith M Erikson; Michael Aschner; Malcolm J Avison; John C Gore
A model for the analysis of competitive relaxation effects of manganese and iron in vivo.
NMR in biomedicine 2009;22(4):391-404.
2009: Andressa Sausen de Freitas; Vinícius Rafael Funck; Mariana dos Santos Rotta; Denise Bohrer; Vanessa Mörschbächer; Robson Luiz Puntel; Cristina W Nogueira; Marcelo Farina; Michael Aschner; João B T Rocha
Diphenyl diselenide, a simple organoselenium compound, decreases methylmercury-induced cerebral, hepatic and renal oxidative stress and mercury deposition in adult mice.
Brain research bulletin 2009;79(1):77-84.
2009: Parvinder Kaur; Lars Evje; Michael Aschner; Tore Syversen
The in vitro effects of selenomethionine on methylmercury-induced neurotoxicity.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(3):378-85.
2009: Daniel H Roos; Robson Luiz Puntel; Matheus M Santos; Diogo O G Souza; Marcelo Farina; Cristina W Nogueira; Michael Aschner; Marilise E Burger; N B V Barbosa; João B T Rocha
Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system.
Toxicology in vitro : an international journal published in association with BIBRA 2009;23(2):302-7.
2009: Roberta de P Martins; Hugo de C Braga; Aline P da Silva; Juliana B Dalmarco; Andreza F de Bem; Adair Roberto S dos Santos; Alcir L Dafre; Moacir Geraldo Pizzolatti; Alexandra Latini; Michael Aschner; Marcelo Farina
Synergistic neurotoxicity induced by methylmercury and quercetin in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2009;47(3):645-9.
2009: Dejan Milatovic; Michael Aschner
Measurement of isoprostanes as markers of oxidative stress in neuronal tissue.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2009;Chapter 12():Unit12.14.
2009: Vanessa A Fitsanakis; Kimberly N Thompson; Sarah E Deery; Dejan Milatovic; Zak K Shihabi; Keith M Erikson; Russell W Brown; Michael Aschner
A chronic iron-deficient/high-manganese diet in rodents results in increased brain oxidative stress and behavioral deficits in the morris water maze.
Neurotoxicity research 2009;15(2):167-78.
2009: Catherine Au; Alexandre Emmanuel Benedetto; Joel Anderson; Arnaud Labrousse; Keith M Erikson; Jonathan J Ewbank; Michael Aschner
SMF-1, SMF-2 and SMF-3 DMT1 orthologues regulate and are regulated differentially by manganese levels in C. elegans.
PloS one 2009;4(11):e7792.
2009: Michael Aschner; Keith M Erikson; Elena Herrero Hernández; Elena Herrero Hernández; Ronald Tjalkens
Manganese and its role in Parkinson's disease: from transport to neuropathology.
Neuromolecular medicine 2009;11(4):252-66.
2008: Zhaobao Yin; Haiyan Jiang; Tore Syversen; João B T Rocha; Marcelo Farina; Michael Aschner
The methylmercury-L-cysteine conjugate is a substrate for the L-type large neutral amino acid transporter.
Journal of neurochemistry 2008;107(4):1083-90.
2008: Daiana Silva Avila; Priscila Gubert; Roselei Fachinetto; Caroline Wagner; Michael Aschner; João Batista Teixeira Rocha; Félix A Soares
Involvement of striatal lipid peroxidation and inhibition of calcium influx into brain slices in neurobehavioral alterations in a rat model of short-term oral exposure to manganese.
Neurotoxicology 2008;29(6):1062-8.
2008: Parvinder Kaur; Ingrid Heggland; Michael Aschner; Tore Syversen
Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.
Neurotoxicology 2008;29(6):978-87.
2008: Maxwell C K Leung; Phillip Williams; Alexandre Emmanuel Benedetto; Catherine Au; Kirsten J Helmcke; Michael Aschner; Joel N Meyer
Caenorhabditis elegans: an emerging model in biomedical and environmental toxicology.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(1):5-28.
2008: A P Marreilha dos Santos; Dinamene Santos; Catherine Au; Dejan Milatovic; Michael Aschner; M Camila C Batoréu
Antioxidants prevent the cytotoxicity of manganese in RBE4 cells.
Brain research 2008;1236():200-5.
2008: Monique M McCallister; Mark Maguire; Aramandla Ramesh; Qiao Aimin; Sheng Liu; Habibeh Khoshbouei; Michael Aschner; Ford F Ebner; Darryl B Hood
Prenatal exposure to benzo(a)pyrene impairs later-life cortical neuronal function.
Neurotoxicology 2008;29(5):846-54.
2008: Parvinder Kaur; Kristina Schulz; Ingrid Heggland; Michael Aschner; Tore Syversen
The use of fluorescence for detecting MeHg-induced ROS in cell cultures.
Toxicology in vitro : an international journal published in association with BIBRA 2008;22(5):1392-8.
2008: Catherine Au; Alexandre Emmanuel Benedetto; Michael Aschner
Manganese transport in eukaryotes: the role of DMT1.
Neurotoxicology 2008;29(4):569-76.
2008: Snjezana Zaja-Milatovic; Ramesh C Gupta; Michael Aschner; Thomas J Montine; Dejan Milatovic
Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum.
Neurotoxicology 2008;29(4):621-7.
2008: Keith M Erikson; David C Dorman; Lawrence H Lash; Michael Aschner
Duration of airborne-manganese exposure in rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.
Neurotoxicology 2008;29(3):377-85.
2008: Adrian K West; Juan Hidalgo; Donnie Eddins; Edward D Levin; Michael Aschner
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition.
Neurotoxicology 2008;29(3):489-503.
2008: Vanessa A Fitsanakis; Na Zhang; Joel Anderson; Keith M Erikson; Malcolm J Avison; John C Gore; Michael Aschner
Measuring brain manganese and iron accumulation in rats following 14 weeks of low-dose manganese treatment using atomic absorption spectroscopy and magnetic resonance imaging.
Toxicological sciences : an official journal of the Society of Toxicology 2008;103(1):116-24.
2008: Zhaoobao Yin; Judy L Aschner; Ana Paula dos Santos; Michael Aschner
Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures.
Brain research 2008;1203():1-11.
2008: Michael Aschner
Re: Blood levels of mercury are related to diagnosis of autism: a reanalysis of an important data set.
Journal of child neurology 2008;23(4):463; author reply 463-5.
2008: Kristin Gellein; Trond Peder Flaten; Keith M Erikson; Michael Aschner; Tore Syversen
Leaching of trace elements from biological tissue by formalin fixation.
Biological trace element research 2008;121(3):221-5.
2008: James Stringari; Adriana K C Nunes; Jeferson Luis Franco; Denise Bohrer; Solange C Garcia; Alcir L Dafre; Dejan Milatovic; Diogo O Souza; João B T Rocha; Michael Aschner; Marcelo Farina
Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain.
Toxicology and applied pharmacology 2008;227(1):147-54.
2008: Offie P Soldin; Daniel M O'Mara; Michael Aschner
Thyroid hormones and methylmercury toxicity.
Biological trace element research 2008;126(1-3):1-12.
2007: George C-T Jiang; Kristen Tidwell; Beth Ann McLaughlin; Jiyang Cai; Ramesh C Gupta; Dejan Milatovic; Richard Nass; Michael Aschner
Neurotoxic potential of depleted uranium effects in primary cortical neuron cultures and in Caenorhabditis elegans.
Toxicological sciences : an official journal of the Society of Toxicology 2007;99(2):553-65.
2007: Dejan Milatovic; Zhaobao Yin; Ramesh C Gupta; Marta Sidoryk; Jan Albrecht; Judy L Aschner; Michael Aschner
Manganese induces oxidative impairment in cultured rat astrocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2007;98(1):198-205.
2007: Michael Aschner; Tomás R Guilarte; Jay S Schneider; Wei Zheng
Manganese: recent advances in understanding its transport and neurotoxicity.
Toxicology and applied pharmacology 2007;221(2):131-47.
2007: Keith M Erikson; David C Dorman; Lawrence H Lash; Michael Aschner
Manganese inhalation by rhesus monkeys is associated with brain regional changes in biomarkers of neurotoxicity.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(2):459-66.
2007: Andreas A Werdich; Franz Baudenbacher; Igor Dzhura; Loice H Jeyakumar; Prince J Kannankeril; Sidney Fleischer; Alison LeGrone; Dejan Milatovic; Michael Aschner; Arnold W Strauss; Mark E Anderson; Vernat J Exil
Polymorphic ventricular tachycardia and abnormal Ca2+ handling in very-long-chain acyl-CoA dehydrogenase null mice.
American journal of physiology. Heart and circulatory physiology 2007;292(5):H2202-11.
2007: Vanessa A Fitsanakis; Greg Piccola; Ana Paula Marreilha dos Santos; Judy L Aschner; Michael Aschner
Putative proteins involved in manganese transport across the blood-brain barrier.
Human & experimental toxicology 2007;26(4):295-302.
2007: Zhaobao Yin; Dejan Milatovic; Judy L Aschner; Tore Syversen; João B T Rocha; Diogo O Souza; Marta Sidoryk; Jan Albrecht; Michael Aschner
Methylmercury induces oxidative injury, alterations in permeability and glutamine transport in cultured astrocytes.
Brain research 2007;1131(1):1-10.
2007: Keith M Erikson; Khristy Thompson; Judy Aschner; Michael Aschner
Manganese neurotoxicity: a focus on the neonate.
Pharmacology & therapeutics 2007;113(2):369-77.
2007: Catherine Au; Lysette Mutkus; Allison Dobson; Judy Riffle; Jennifer Lalli; Michael Aschner
Effects of nanoparticles on the adhesion and cell viability on astrocytes.
Biological trace element research 2007;120(1-3):248-56.
2007: Stephanie J Garcia; Kristin Gellein; Tore Syversen; Michael Aschner
Iron deficient and manganese supplemented diets alter metals and transporters in the developing rat brain.
Toxicological sciences : an official journal of the Society of Toxicology 2007;95(1):205-14.
2006: Michael Aschner; Tore Syversen; Diogo O Souza; João B T Rocha
Metallothioneins: mercury species-specific induction and their potential role in attenuating neurotoxicity.
Experimental biology and medicine (Maywood, N.J.) 2006;231(9):1468-73.
2006: Stephen J Walker; Jeffrey Segal; Michael Aschner
Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge.
Neurotoxicology 2006;27(5):685-92.
2006: Michael D Taylor; Keith M Erikson; Allison W Dobson; Vanessa A Fitsanakis; David C Dorman; Michael Aschner
Effects of inhaled manganese on biomarkers of oxidative stress in the rat brain.
Neurotoxicology 2006;27(5):788-97.
2006: Vanessa A Fitsanakis; Na Zhang; Malcolm J Avison; John C Gore; Judy L Aschner; Michael Aschner
The use of magnetic resonance imaging (MRI) in the study of manganese neurotoxicity.
Neurotoxicology 2006;27(5):798-806.
2006: Michael Aschner; B Lukey; A Tremblay
The Manganese Health Research Program (MHRP): status report and future research needs and directions.
Neurotoxicology 2006;27(5):733-6.
2006: Stephanie J Garcia; Kristin Gellein; Tore Syversen; Michael Aschner
A manganese-enhanced diet alters brain metals and transporters in the developing rat.
Toxicological sciences : an official journal of the Society of Toxicology 2006;92(2):516-25.
2006: Vanessa A Fitsanakis; Catherine Au; Keith M Erikson; Michael Aschner
The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation.
Neurochemistry international 2006;48(6-7):426-33.
2006: Michael Aschner
The transport of manganese across the blood-brain barrier.
Neurotoxicology 2006;27(3):311-4.
2006: Allison W Dobson; Anna K Lack; Keith M Erikson; Michael Aschner
Depleted uranium is not toxic to rat brain endothelial (RBE4) cells.
Biological trace element research 2006;110(1):61-72.
2006: George C-T Jiang; Michael Aschner
Neurotoxicity of depleted uranium: reasons for increased concern.
Biological trace element research 2006;110(1):1-17.
2006: Lysette Mutkus; Judy L Aschner; Tore Syversen; Gouri Shanker; Ursula Sonnewald; Michael Aschner
Mercuric chloride inhibits the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells.
Biological trace element research 2006;109(3):267-80.
2006: Michael Aschner; David C Dorman
Manganese: pharmacokinetics and molecular mechanisms of brain uptake.
Toxicological reviews 2006;25(3):147-54.
2006: Keith M Erikson; David C Dorman; Vanessa A Fitsanakis; Lawrence H Lash; Michael Aschner
Alterations of oxidative stress biomarkers due to in utero and neonatal exposures of airborne manganese.
Biological trace element research 2006;111(1-3):199-215.
2006: Vanessa A Fitsanakis; Keith M Erikson; Stephanie J Garcia; Lars Evje; Tore Syversen; Michael Aschner
Brain accumulation of depleted uranium in rats following 3- or 6-month treatment with implanted depleted uranium pellets.
Biological trace element research 2006;111(1-3):185-97.
2006: Michael Aschner; Vanessa A Fitsanakis; Ana Paula Marreilha dos Santos; Luisa Olivi; Joseph Bressler
Blood-brain barrier and cell-cell interactions: methods for establishing in vitro models of the blood-brain barrier and transport measurements.
Methods in molecular biology (Clifton, N.J.) 2006;341():1-15.
2006: Dejan Milatovic; Ramesh C Gupta; Michael Aschner
Anticholinesterase toxicity and oxidative stress.
TheScientificWorldJournal 2006;6():295-310.
2006: Ashley N Donahue; Michael Aschner; Lawrence H Lash; Tore Syversen; William E Sonntag
Growth hormone administration to aged animals reduces disulfide glutathione levels in hippocampus.
Mechanisms of ageing and development 2006;127(1):57-63.
2006: Vanessa A Fitsanakis; Greg Piccola; Judy L Aschner; Michael Aschner
Characteristics of manganese (Mn) transport in rat brain endothelial (RBE4) cells, an in vitro model of the blood-brain barrier.
Neurotoxicology 2006;27(1):60-70.
2006: Keith M Erikson; Michael Aschner
Increased manganese uptake by primary astrocyte cultures with altered iron status is mediated primarily by divalent metal transporter.
Neurotoxicology 2006;27(1):125-30.
2005: Lysette Mutkus; Judy L Aschner; Tore Syversen; Michael Aschner
Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells.
Biological trace element research 2005;107(3):231-45.
2005: Lysette Mutkus; Judy L Aschner; Vanessa A Fitsanakis; Michael Aschner
The in vitro uptake of glutamate in GLAST and GLT-1 transfected mutant CHO-K1 cells is inhibited by manganese.
Biological trace element research 2005;107(3):221-30.
2005: Keith M Erikson; Carrie E John; Sara R Jones; Michael Aschner
Manganese accumulation in striatum of mice exposed to toxic doses is dependent upon a functional dopamine transporter.
Environmental toxicology and pharmacology 2005;20(3):390-4.
2005: Michael Aschner; Adrian K West
The role of MT in neurological disorders.
Journal of Alzheimer's disease : JAD 2005;8(2):139-45; discussion 209-15.
2005: Michael Aschner; Qi Wu; Marvin A Friedman
Effects of acrylamide on primary neonatal rat astrocyte functions.
Annals of the New York Academy of Sciences 2005;1053():444-54.
2005: Qi Wu; Marta Sidoryk; Lysette Mutkus; Magdalena Zielińska; Jan Albrecht; Michael Aschner
Acrylamide stimulates glutamine uptake in Fischer 344 rat astrocytes by a mechanism involving upregulation of the amino acid transport system N.
Annals of the New York Academy of Sciences 2005;1053():435-43.
2005: Judy L Aschner; Michael Aschner
Nutritional aspects of manganese homeostasis.
Molecular aspects of medicine 2005;26(4-5):353-62.
2005: Vanessa A Fitsanakis; Greg Piccola; Judy L Aschner; Michael Aschner
Manganese transport by rat brain endothelial (RBE4) cell-based transwell model in the presence of astrocyte conditioned media.
Journal of neuroscience research 2005;81(2):235-43.
2005: Gouri Shanker; Tore Syversen; Judy L Aschner; Michael Aschner
Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes.
Brain research. Molecular brain research 2005;137(1-2):11-22.
2005: Michael Aschner; Tore Syversen
Methylmercury: recent advances in the understanding of its neurotoxicity.
Therapeutic drug monitoring 2005;27(3):278-83.
2005: Keith M Erikson; Tore Syversen; Judy L Aschner; Michael Aschner
Interactions between excessive manganese exposures and dietary iron-deficiency in neurodegeneration.
Environmental toxicology and pharmacology 2005;19(3):415-21.
2005: Keith M Erikson; David C Dorman; Lawrence H Lash; Michael Aschner
Persistent alterations in biomarkers of oxidative stress resulting from combined in utero and neonatal manganese inhalation.
Biological trace element research 2005;104(2):151-63.
2005: Vanessa A Fitsanakis; Michael Aschner
The importance of glutamate, glycine, and gamma-aminobutyric acid transport and regulation in manganese, mercury and lead neurotoxicity.
Toxicology and applied pharmacology 2005;204(3):343-54.
2005: Lysette Mutkus; Judy L Aschner; Tore Syversen; Gouri Shanker; Ursula Sonnewald; Michael Aschner
In vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells is inhibited by the ethylmercury-containing preservative thimerosal.
Biological trace element research 2005;105(1-3):71-86.
2005: Michael Aschner; Keith M Erikson; David C Dorman
Manganese dosimetry: species differences and implications for neurotoxicity.
Critical reviews in toxicology 2005;35(1):1-32.
2004: Keith M Erikson; Allison W Dobson; David C Dorman; Michael Aschner
Manganese exposure and induced oxidative stress in the rat brain.
The Science of the total environment 2004;334-335():409-16.
2004: Michael Aschner; Tore Syversen
Neurotoxicology: principles and considerations of in vitro assessment.
Alternatives to laboratory animals : ATLA 2004;32(4):323-7.
2004: Gouri Shanker; Judy L Aschner; Tore Syversen; Michael Aschner
Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury.
Brain research. Molecular brain research 2004;128(1):48-57.
2004: Keith M Erikson; David C Dorman; Lawrence H Lash; Allison W Dobson; Michael Aschner
Airborne manganese exposure differentially affects end points of oxidative stress in an age- and sex-dependent manner.
Biological trace element research 2004;100(1):49-62.
2004: Denise L Stredrick; Alan H Stokes; Travis J Worst; Willard M Freeman; Elizabeth A Johnson; Lawrence H Lash; Michael Aschner; Kent Vrana
Manganese-induced cytotoxicity in dopamine-producing cells.
Neurotoxicology 2004;25(4):543-53.
2004: Keith M Erikson; Tore Syversen; Eiliv Steinnes; Michael Aschner
Globus pallidus: a target brain region for divalent metal accumulation associated with dietary iron deficiency.
The Journal of nutritional biochemistry 2004;15(6):335-41.
2004: Allison W Dobson; Keith M Erikson; Michael Aschner
Manganese neurotoxicity.
Annals of the New York Academy of Sciences 2004;1012():115-28.
2004: Gouri Shanker; Robert E Hampson; Michael Aschner
Methylmercury stimulates arachidonic acid release and cytosolic phospholipase A2 expression in primary neuronal cultures.
Neurotoxicology 2004;25(3):399-406.
2003: Gouri Shanker; Tore Syversen; Michael Aschner
Astrocyte-mediated methylmercury neurotoxicity.
Biological trace element research 2003;95(1):1-10.
2003: Keith M Erikson; Michael Aschner
Manganese neurotoxicity and glutamate-GABA interaction.
Neurochemistry international 2003;43(4-5):475-80.
2003: Jian Yang; Michael Aschner
Developmental aspects of blood-brain barrier (BBB) and rat brain endothelial (RBE4) cells as in vitro model for studies on chlorpyrifos transport.
Neurotoxicology 2003;24(4-5):741-5.
2003: Kent Vrana; Willard M Freeman; Michael Aschner
Use of microarray technologies in toxicology research.
Neurotoxicology 2003;24(3):321-32.
2003: Michael Aschner; Cheng-Chen Cao; Qi Wu; Marvin A Friedman
The acute effects of acrylamide on astrocyte functions.
Annals of the New York Academy of Sciences 2003;993():296-304; discussion 345-9.
2003: Gouri Shanker; Michael Aschner
Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants.
Brain research. Molecular brain research 2003;110(1):85-91.
2003: Allison W Dobson; Sarah Weber; David C Dorman; Lawrence K Lash; Keith M Erikson; Michael Aschner
Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate.
Biological trace element research 2003;93(1-3):113-26.
2002: Jeffrey W Allen; Gouri Shanker; Kim H Tan; Michael Aschner
The consequences of methylmercury exposure on interactive functions between astrocytes and neurons.
Neurotoxicology 2002;23(6):755-9.
2002: Jeffrey W Allen; Lysette Mutkus; Michael Aschner
Chronic ethanol produces increased taurine transport and efflux in cultured astrocytes.
Neurotoxicology 2002;23(6):693-700.
2002: Gouri Shanker; Lysette Mutkus; Stephen J Walker; Michael Aschner
Methylmercury enhances arachidonic acid release and cytosolic phospholipase A2 expression in primary cultures of neonatal astrocytes.
Brain research. Molecular brain research 2002;106(1-2):1-11.
2002: Keith M Erikson; Michael Aschner
Manganese causes differential regulation of glutamate transporter (GLAST) taurine transporter and metallothionein in cultured rat astrocytes.
Neurotoxicology 2002;23(4-5):595-602.
2002: Michael Aschner; Ursula Sonnewald; Kim H Tan
Astrocyte modulation of neurotoxic injury.
Brain pathology (Zurich, Switzerland) 2002;12(4):475-81.
2002: Michael Aschner
Neurotoxic mechanisms of fish-borne methylmercury.
Environmental toxicology and pharmacology 2002;12(2):101-4.
2002: Keith M Erikson; Robert L Suber; Michael Aschner
Glutamate/aspartate transporter (GLAST), taurine transporter and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate or manganese sulfate.
Neurotoxicology 2002;23(3):281-8.
2002: Sarah Weber; David C Dorman; Lawrence H Lash; Keith M Erikson; Kent Vrana; Michael Aschner
Effects of manganese (Mn) on the developing rat brain: oxidative-stress related endpoints.
Neurotoxicology 2002;23(2):169-75.
2002: Michael Aschner; Gouri Shanker; Keith M Erikson; Jian Yang; Lysette Mutkus
The uptake of manganese in brain endothelial cultures.
Neurotoxicology 2002;23(2):165-8.
2002: Michael Aschner
Open issues from the 15th International Conference on Manganese.
Neurotoxicology 2002;23(2):123-5.
2002: Michael Aschner; S J Walker
The neuropathogenesis of mercury toxicity.
Molecular psychiatry 2002;7 Suppl 2():S40-1.
2002: Keith M Erikson; Zak K Shihabi; Judy L Aschner; Michael Aschner
Manganese accumulates in iron-deficient rat brain regions in a heterogeneous fashion and is associated with neurochemical alterations.
Biological trace element research 2002;87(1-3):143-56.
2001: Jian Yang; Lysette Mutkus; D Sumner; J T Stevens; JC Eldridge; Jack W Strandhoy; Michael Aschner
Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium.
Brain research. Molecular brain research 2001;97(1):43-50.
2001: Michael Aschner; R F Seegal
Selected presentations and general discussion: session IX summary and research needs.
Neurotoxicology 2001;22(6):849-52.
2001: Gouri Shanker; Michael Aschner
Identification and characterization of uptake systems for cystine and cysteine in cultured astrocytes and neurons: evidence for methylmercury-targeted disruption of astrocyte transport.
Journal of neuroscience research 2001;66(5):998-1002.
2001: Michael Aschner; Lysette Mutkus; Jeffrey W Allen
Aspartate and glutamate transport in acutely and chronically ethanol exposed neonatal rat primary astrocyte cultures.
Neurotoxicology 2001;22(5):601-5.
2001: Gouri Shanker; Jeffrey W Allen; Lysette Mutkus; Michael Aschner
Methylmercury inhibits cysteine uptake in cultured primary astrocytes, but not in neurons.
Brain research 2001;914(1-2):159-65.
2001: Jeffrey W Allen; H El-Oqayli; Michael Aschner; Tore Syversen; Ursula Sonnewald
Methylmercury has a selective effect on mitochondria in cultured astrocytes in the presence of [U-(13)C]glutamate.
Brain research 2001;908(2):149-54.
2001: Michael Aschner; Lysette Mutkus; Jeffrey W Allen
Amino acid uptake and release in primary astrocyte cultures exposed to ethanol.
Annals of the New York Academy of Sciences 2001;939():23-7.
2001: Gouri Shanker; Jeffrey W Allen; Lysette Mutkus; Michael Aschner
The uptake of cysteine in cultured primary astrocytes and neurons.
Brain research 2001;902(2):156-63.
2001: Jeffrey W Allen; Lysette Mutkus; Michael Aschner
Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase.
Brain research 2001;902(1):92-100.
2001: Michael Aschner; Jeffrey W Allen; Lysette Mutkus; C Cao
Ethanol-induced swelling in neonatal rat primary astrocyte cultures.
Brain research 2001;900(2):219-26.
2001: Jeffrey W Allen; Gouri Shanker; Michael Aschner
Methylmercury inhibits the in vitro uptake of the glutathione precursor, cystine, in astrocytes, but not in neurons.
Brain research 2001;894(1):131-40.
2001: Jeffrey W Allen; Lysette Mutkus; Michael Aschner
Mercuric chloride, but not methylmercury, inhibits glutamine synthetase activity in primary cultures of cortical astrocytes.
Brain research 2001;891(1-2):148-57.
2001: Jeffrey W Allen; Lysette Mutkus; Michael Aschner
Isolation of neonatal rat cortical astrocytes for primary cultures.
Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2001;Chapter 12():Unit12.4.
2000: Michael Aschner
Neuron-astrocyte interactions: implications for cellular energetics and antioxidant levels.
Neurotoxicology 2000;21(6):1101-7.
2000: Michael Aschner; Jeffrey W Allen
Astrocytes in methylmercury, ammonia, methionine sulfoximine and alcohol-induced neurotoxicity.
Neurotoxicology 2000;21(4):573-9.
2000: Michael Aschner; CP Yao; Jeffrey W Allen; Kim H Tan
Methylmercury alters glutamate transport in astrocytes.
Neurochemistry international 2000;37(2-3):199-206.
2000: Michael Aschner
Astrocytic swelling, phospholipase A2, glutathione and glutamate: interactions in methylmercury-induced neurotoxicity.
Cellular and molecular biology (Noisy-le-Grand, France) 2000;46(4):843-54.
2000: Michael Aschner
Manganese: brain transport and emerging research needs.
Environmental health perspectives 2000;108 Suppl 3():429-32.
2000: A H Stokes; D Y Lewis; Lawrence H Lash; W Gray Jerome; K W Grant; Michael Aschner; Kent Vrana
Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis.
Brain research 2000;858(1):1-8.
2000: CP Yao; Jeffrey W Allen; Lysette Mutkus; S B Xu; Kim H Tan; Michael Aschner
Foreign metallothionein-I expression by transient transfection in MT-I and MT-II null astrocytes confers increased protection against acute methylmercury cytotoxicity.
Brain research 2000;855(1):32-8.
2000: Michael Aschner
Interactions between pesticides and glia: an unexplored experimental field.
Neurotoxicology 2000;21(1-2):175-80.
1999: Michael Aschner; Kent Vrana; W Zheng
Manganese uptake and distribution in the central nervous system (CNS).
Neurotoxicology 1999;20(2-3):173-80.
1999: CP Yao; Jeffrey W Allen; DR Conklin; Michael Aschner
Transfection and overexpression of metallothionein-I in neonatal rat primary astrocyte cultures and in astrocytoma cells increases their resistance to methylmercury-induced cytotoxicity.
Brain research 1999;818(2):414-20.
1999: Michael Aschner; B A Bennett
Astrocyte and neuron coculturing method.
Methods in molecular medicine 1999;22():133-44.
1999: CP Yao; Jeffrey W Allen; Michael Aschner
Metallothioneins attenuate methylmercury-induced neurotoxicity in cultured astrocytes and astrocytoma cells.
Annals of the New York Academy of Sciences 1999;890():223-6.
1999: Michael Aschner; J W Allen; H K Kimelberg; Richard M LoPachin; W J Streit
Glial cells in neurotoxicity development.
Annual review of pharmacology and toxicology 1999;39():151-73.
1998: Michael Aschner; DR Conklin; CP Yao; Jeffrey W Allen; Kim H Tan
Induction of astrocyte metallothioneins (MTs) by zinc confers resistance against the acute cytotoxic effects of methylmercury on cell swelling, Na+ uptake, and K+ release.
Brain research 1998;813(2):254-61.
1998: Michael Aschner; D Vitarella; Jeffrey W Allen; DR Conklin; KS Cowan
Methylmercury-induced inhibition of regulatory volume decrease in astrocytes: characterization of osmoregulator efflux and its reversal by amiloride.
Brain research 1998;811(1-2):133-42.
1998: Michael Aschner
Metallothionein (MT) isoforms in the central nervous system (CNS): regional and cell-specific distribution and potential functions as an antioxidant.
Neurotoxicology 1998;19(4-5):653-60.
1998: Michael Aschner; D Vitarella; Jeffrey W Allen; DR Conklin; KS Cowan
Methylmercury-induced astrocytic swelling is associated with activation of the Na+/H+ antiporter, and is fully reversed by amiloride.
Brain research 1998;799(2):207-14.
1998: DR Conklin; Kim H Tan; Michael Aschner
Dimethyl sulfoxide, but not acidosis-induced metallothionein mRNA expression in neonatal rat primary astrocyte cultures is inhibited by the bioflavonoid, quercetin.
Brain research 1998;794(2):304-8.
1998: Michael Aschner
Astrocytes as mediators of immune and inflammatory responses in the CNS.
Neurotoxicology 1998;19(2):269-81.
1998: Michael Aschner; S Stark; Kent Vrana; DR Conklin
Acidosis-induced metallothionein (MT) mRNA expression in neonatal rat primary astrocyte cultures.
Neurotoxicology 1998;19(2):227-36.
1998: Michael Aschner
Astrocytic functions and physiological reactions to injury: the potential to induce and/or exacerbate neuronal dysfunction--a forum position paper.
Neurotoxicology 1998;19(1):7-17; discussion 37-8.
1997: Michael Aschner; Fritz Lorscheider; KS Cowan; DR Conklin; MJ Vimy; Lawrence H Lash
Metallothionein induction in fetal rat brain and neonatal primary astrocyte cultures by in utero exposure to elemental mercury vapor (Hg0).
Brain research 1997;778(1):222-32.
1997: Michael Aschner
Astrocyte metallothioneins (MTs) and their neuroprotective role.
Annals of the New York Academy of Sciences 1997;825():334-47.
1997: Michael Aschner; DR Conklin; Judy L Aschner
Induction of metallothionein-I (MT-I) mRNA in primary astrocyte cultures is mediated by hypotonicity and not ethanol (EtOH) per se.
Brain research 1997;770(1-2):289-93.
1997: Michael Aschner; M G Cherian; C D Klaassen; R D Palmiter; J C Erickson; Ashley I Bush
Metallothioneins in brain--the role in physiology and pathology.
Toxicology and applied pharmacology 1997;142(2):229-42.
1996: D Vitarella; DR Conklin; Harold K Kimelberg; Michael Aschner
Metallothionein induction protects swollen rat primary astrocyte cultures from methylmercury-induced inhibition of regulatory volume decrease.
Brain research 1996;738(2):213-21.
1996: D Vitarella; Harold K Kimelberg; Michael Aschner
Inhibition of regulatory volume decrease in swollen rat primary astrocyte cultures by methylmercury is due to increased amiloride-sensitive Na+ uptake.
Brain research 1996;732(1-2):169-78.
1996: K Cowan; DR Conklin; Michael Aschner
Metallothionein induction by bismuth in neonatal rat primary astrocyte cultures.
Brain research 1996;732(1-2):106-12.
1996: Michael Aschner
Astrocytes as modulators of mercury-induced neurotoxicity.
Neurotoxicology 1996;17(3-4):663-9.
1996: Michael Aschner
The functional significance of brain metallothioneins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(10):1129-36.
1996: D Vitarella; Harold K Kimelberg; Michael Aschner
Regulatory volume decrease in primary astrocyte cultures: relevance to methylmercury neurotoxicity.
Neurotoxicology 1996;17(1):117-23.
1996: Michael Aschner; L Rising; K J Mullaney
Differential sensitivity of neonatal rat astrocyte cultures to mercuric chloride (MC) and methylmercury (MeHg): studies on K+ and amino acid transport and metallothionein (MT) induction.
Neurotoxicology 1996;17(1):107-16.
1996: Michael Aschner
Methylmercury in astrocytes--what possible significance?
Neurotoxicology 1996;17(1):93-106.
1995: L Rising; D Vitarella; Harold K Kimelberg; Michael Aschner
Metallothionein induction in neonatal rat primary astrocyte cultures protects against methylmercury cytotoxicity.
Journal of neurochemistry 1995;65(4):1562-8.
1995: Michael Aschner; K J Mullaney; D E Wagoner; Lawrence H Lash; Harold K Kimelberg
Adenosine modulates methylmercuric chloride (MeHgCl)-induced D-aspartate release from neonatal rat primary astrocyte cultures.
Brain research 1995;689(1):1-8.
1995: L Rising; D Vitarella; Harold K Kimelberg; Michael Aschner
Cadmium chloride (CdCl2)-induced metallothionein (MT) expression in neonatal rat primary astrocyte cultures.
Brain research 1995;678(1-2):91-8.
1994: Michael Aschner; K J Mullaney; M N Fehm; D E Wagoner; D Vitarella
Astrocytes as potential modulators of mercuric chloride neurotoxicity.
Cellular and molecular neurobiology 1994;14(6):637-52.
1994: Michael Aschner; K J Mullaney; D Wagoner; Lawrence H Lash; Harold K Kimelberg
Intracellular glutathione (GSH) levels modulate mercuric chloride (MC)- and methylmercuric chloride (MeHgCl)-induced amino acid release from neonatal rat primary astrocytes cultures.
Brain research 1994;664(1-2):133-40.
1994: D Vitarella; D J DiRisio; Harold K Kimelberg; Michael Aschner
Potassium and taurine release are highly correlated with regulatory volume decrease in neonatal primary rat astrocyte cultures.
Journal of neurochemistry 1994;63(3):1143-9.
1994: Michael Aschner; K J Mullaney; M N Fehm; D Vitarella; D E Wagoner; Harold K Kimelberg
The role of sulfhydryl groups in D-aspartate and rubidium release from neonatal rat primary astrocyte cultures.
Brain research 1994;648(1):16-23.
1994: K J Mullaney; M N Fehm; D Vitarella; D E Wagoner; Michael Aschner
The role of -SH groups in methylmercuric chloride-induced D-aspartate and rubidium release from rat primary astrocyte cultures.
Brain research 1994;641(1):1-9.
1994: Michael Aschner; M Gannon
Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms.
Brain research bulletin 1994;33(3):345-9.
1994: V Dave; K J Mullaney; Susan K Goderie; Harold K Kimelberg; Michael Aschner
Astrocytes as mediators of methylmercury neurotoxicity: effects on D-aspartate and serotonin uptake.
Developmental neuroscience 1994;16(3-4):222-31.
1993: K J Mullaney; D Vitarella; J Albrecht; Harold K Kimelberg; Michael Aschner
Stimulation of D-aspartate efflux by mercuric chloride from rat primary astrocyte cultures.
Brain research. Developmental brain research 1993;75(2):261-8.
1993: V Dave; D Vitarella; Judy L Aschner; P Fletcher; Harold K Kimelberg; Michael Aschner
Lead increases inositol 1,4,5-trisphosphate levels but does not interfere with calcium transients in primary rat astrocytes.
Brain research 1993;618(1):9-18.
1993: Michael Aschner; Richard M LoPachin
Astrocytes: targets and mediators of chemical-induced CNS injury.
Journal of toxicology and environmental health 1993;38(3):329-42.
1993: Michael Aschner; Y L Du; M Gannon; Harold K Kimelberg
Methylmercury-induced alterations in excitatory amino acid transport in rat primary astrocyte cultures.
Brain research 1993;602(2):181-6.
1993: Richard M LoPachin; Michael Aschner
Glial-neuronal interactions: relevance to neurotoxic mechanisms.
Toxicology and applied pharmacology 1993;118(2):141-58.
1992: Michael Aschner; M Gannon; Harold K Kimelberg
Interactions of trimethyl tin (TMT) with rat primary astrocyte cultures: altered uptake and efflux of rubidium, L-glutamate and D-aspartate.
Brain research 1992;582(2):181-5.
1992: Michael Aschner; M Gannon; Harold K Kimelberg
Manganese uptake and efflux in cultured rat astrocytes.
Journal of neurochemistry 1992;58(2):730-5.
1992: Michael Aschner; Judy L Aschner
Cellular and molecular effects of trimethyltin and triethyltin: relevance to organotin neurotoxicity.
Neuroscience and biobehavioral reviews 1992;16(4):427-35.
1991: Michael Aschner; N B Eberle; Harold K Kimelberg
Interactions of methylmercury with rat primary astrocyte cultures: methylmercury efflux.
Brain research 1991;554(1-2):10-4.
1991: Michael Aschner; R Chen; Harold K Kimelberg
Effects of mercury and lead on rubidium uptake and efflux in cultured rat astrocytes.
Brain research bulletin 1991;26(4):639-42.
1991: Michael Aschner; Judy L Aschner
Manganese neurotoxicity: cellular effects and blood-brain barrier transport.
Neuroscience and biobehavioral reviews 1991;15(3):333-40.
1990: Michael Aschner; N B Eberle; Kenneth W Miller; Harold K Kimelberg
Interactions of methylmercury with rat primary astrocyte cultures: inhibition of rubidium and glutamate uptake and induction of swelling.
Brain research 1990;530(2):245-50.
1990: Michael Aschner; N B Eberle; Susan K Goderie; Harold K Kimelberg
Methylmercury uptake in rat primary astrocyte cultures: the role of the neutral amino acid transport system.
Brain research 1990;521(1-2):221-8.
1990: Michael Aschner; Judy L Aschner
Manganese transport across the blood-brain barrier: relationship to iron homeostasis.
Brain research bulletin 1990;24(6):857-60.
1990: Michael Aschner; Judy L Aschner
Mercury neurotoxicity: mechanisms of blood-brain barrier transport.
Neuroscience and biobehavioral reviews 1990;14(2):169-76.
1989: Michael Aschner
Brain, kidney and liver 203Hg-methyl mercury uptake in the rat: relationship to the neutral amino acid carrier.
Pharmacology & toxicology 1989;65(1):17-20.