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Juan Asenjo
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Research Profile (preview)
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Occupations
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Network (preview)
33
Andrews, Barbara
8
Lienqueo, Elena
8
Mahn, Andrea
8
Salgado, Cristian
6
Rapaport, Ivan
4
Salazar, Oriana
4
Merchuk, Jose
3
Montagna, Jorge
3
Pinto, José
3
Iribarren, Oscar
3
Vecchietti, Aldo
3
Franco, Telma
2
Olivera-Nappa, Alvaro
2
Savva, Demetris
2
Shene, C
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All Publications
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2009: Díaz H; Andrews B A; Hayes A; Castrillo J; Oliver S G; Asenjo J A
Global gene expression in recombinant and non-recombinant yeast Saccharomyces cerevisiae in three different metabolic states.
Biotechnology advances 2009;27(6):1092-117.
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2009: Orellana C A; Shene C; Asenjo J A
Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography applied to high protein concentration.
Biotechnology and bioengineering 2009;104(3):572-81.
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2009: Contador Carolina A; Rizk Matthew L; Asenjo Juan A; Liao James C
Ensemble modeling for strain development of L-lysine-producing Escherichia coli.
Metabolic engineering 2009;11(4-5):221-33.
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2009: Hold C; Andrews B A; Asenjo J A
A stoichiometric model of Acidithiobacillus ferrooxidans ATCC 23270 for metabolic flux analysis.
Biotechnology and bioengineering 2009;102(5):1448-59.
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2009: Lienqueo María Elena; Shene Carolina; Asenjo Juan
Optimization of hydrophobic interaction chromatography using a mathematical model of elution curves of a protein mixture.
Journal of molecular recognition : JMR 2009;22(2):110-20.
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2009: Asenjo J A; Andrews B A
Protein purification using chromatography: selection of type, modelling and optimization of operating conditions.
Journal of molecular recognition : JMR 2009;22(2):65-76.
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2009: Gerdtzen Ziomara P; Salgado J Cristian; Osses Axel; Asenjo Juan A; Rapaport Ivan; Andrews Barbara A
Modeling heterocyst pattern formation in cyanobacteria.
BMC bioinformatics 2009;10 Suppl 6():S16.
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2008: Sepulveda Dario E; Andrews Barbara A; Asenjo Juan A; Papoutsakis Eleftherios Terry
Comparative transcriptional analysis of embryoid body versus two-dimensional differentiation of murine embryonic stem cells.
Tissue engineering. Part A 2008;14(10):1603-14.
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2008: Acevedo Juan Pablo; Reyes Fernando; Parra Loreto P; Salazar Oriana; Andrews Barbara A; Asenjo Juan A
Cloning of complete genes for novel hydrolytic enzymes from Antarctic sea water bacteria by use of an improved genome walking technique.
Journal of biotechnology 2008;133(3):277-86.
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2008: Salgado J Cristian; Andrews Barbara A; Ortuzar Maria Fernanda; Asenjo Juan A
Prediction of the partitioning behaviour of proteins in aqueous two-phase systems using only their amino acid composition.
Journal of chromatography. A 2008;1178(1-2):134-44.
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2007: Salazar Oriana; Asenjo Juan A
Enzymatic lysis of microbial cells.
Biotechnology letters 2007;29(7):985-94.
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2007: Lienqueo M Elena; Mahn Andrea; Salgado J Cristian; Asenjo Juan A
Current insights on protein behaviour in hydrophobic interaction chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;849(1-2):53-68.
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2007: Mahn Andrea; Lienqueo M Elena; Asenjo Juan A
Optimal operation conditions for protein separation in hydrophobic interaction chromatography.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;849(1-2):236-42.
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2006: Shene C; Lucero A; Andrews B A; Asenjo J A
Mathematical modeling of elution curves for a protein mixture in ion exchange chromatography and for the optimal selection of operational conditions.
Biotechnology and bioengineering 2006;95(4):704-13.
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2006: Salazar Oriana; Basso Caterina; Barba Paola; Orellana Claudia; Asenjo Juan A
Improvement of the lytic properties of a beta-1,3-glucanase by directed evolution.
Molecular biotechnology 2006;33(3):211-9.
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2006: Lienqueo M E; Mahn A; Navarro G; Salgado J C; Perez-Acle T; Rapaport I; Asenjo J A
New approaches for predicting protein retention time in hydrophobic interaction chromatography.
Journal of molecular recognition : JMR 2006;19(4):260-9.
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2006: Salgado J Cristian; Rapaport Ivan; Asenjo Juan A
Predicting the behaviour of proteins in hydrophobic interaction chromatography. 2. Using a statistical description of their surface amino acid distribution.
Journal of chromatography. A 2006;1107(1-2):120-9.
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2006: Salgado J Cristian; Rapaport Ivan; Asenjo Juan A
Predicting the behaviour of proteins in hydrophobic interaction chromatography. 1: Using the hydrophobic imbalance (HI) to describe their surface amino acid distribution.
Journal of chromatography. A 2006;1107(1-2):110-9.
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2005: Salgado J Cristian; Rapaport Ivan; Asenjo Juan A
Prediction of retention times of proteins in hydrophobic interaction chromatography using only their amino acid composition.
Journal of chromatography. A 2005;1098(1-2):44-54.
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2005: Mahn Andrea; Asenjo Juan A
Prediction of protein retention in hydrophobic interaction chromatography.
Biotechnology advances 2005;23(5):359-68.
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2005: Salgado J Cristian; Rapaport Ivan; Asenjo Juan A
Is it possible to predict the average surface hydrophobicity of a protein using only its amino acid composition?
Journal of chromatography. A 2005;1075(1-2):133-43.
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2005: Andrews B A; Schmidt A S; Asenjo J A
Correlation for the partition behavior of proteins in aqueous two-phase systems: effect of surface hydrophobicity and charge.
Biotechnology and bioengineering 2005;90(3):380-90.
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2005: Mahn A; Zapata-Torres G; Asenjo J A
A theory of protein-resin interaction in hydrophobic interaction chromatography.
Journal of chromatography. A 2005;1066(1-2):81-8.
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2004: Mahn A; Lienqueo M E; Asenjo J A
Effect of surface hydrophobicity distribution on retention of ribonucleases in hydrophobic interaction chromatography.
Journal of chromatography. A 2004;1043(1):47-55.
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2004: Iribarren Oscar A; Montagna Jorge M; Vecchietti Aldo R; Andrews Barbara; Asenjo Juan A; Pinto José M
Optimal process synthesis for the production of multiple recombinant proteins.
Biotechnology progress 2004;20(4):1032-43.
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2004: Olivera-Nappa A; Lagomarsino G; Andrews B A; Asenjo J A
Effect of electrostatic energy on partitioning of proteins in aqueous two-phase systems.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;807(1):81-6.
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2004: Olivera-Nappa Alvaro; Andrews Barbara A; Asenjo Juan A
A mixed mechanistic-electrostatic model to explain pH dependence of glycosyl hydrolase enzyme activity.
Biotechnology and bioengineering 2004;86(5):573-86.
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2004: Asenjo J A; Andrews B A
Is there a rational method to purify proteins? From expert systems to proteomics.
Journal of molecular recognition : JMR 2004;17(3):236-47.
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2003: Lienqueo M Elena; Mahn Andrea; Vásquez Liliana; Asenjo Juan A
Methodology for predicting the separation of proteins by hydrophobic interaction chromatography and its application to a cell extract.
Journal of chromatography. A 2003;1009(1-2):189-96.
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2003: Shene C; Andrews B A; Asenjo J A
Study of recombinant micro-organism populations characterized by their plasmid content per cell using a segregated model.
Bioprocess and biosystems engineering 2003;25(6):333-40.
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2003: Gonzalez Ramon; Andrews Barbara A; Molitor Julia; Asenjo Juan A
Metabolic analysis of the synthesis of high levels of intracellular human SOD in Saccharomyces cerevisiae rhSOD 2060 411 SGA122.
Biotechnology and bioengineering 2003;82(2):152-69.
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2002: Lienqueo M Elena; Mahn Andrea; Asenjo Juan A
Mathematical correlations for predicting protein retention times in hydrophobic interaction chromatography.
Journal of chromatography. A 2002;978(1-2):71-9.
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2002: Asenjo J A; Mistry S L; Andrews B A; Merchuk J C
Phase separation rates of aqueous two-phase systems: correlation with system properties.
Biotechnology and bioengineering 2002;79(2):217-23.
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2002: Berggren Kristina; Wolf Alejandro; Asenjo Juan A; Andrews Barbara A; Tjerneld Folke
The surface exposed amino acid residues of monomeric proteins determine the partitioning in aqueous two-phase systems.
Biochimica et biophysica acta 2002;1596(2):253-68.
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2002: Gonz lez Ramon; Andrews Barbara A; Asenjo Juan A
Kinetic model of BiP- and PDI-mediated protein folding and assembly.
Journal of theoretical biology 2002;214(4):529-37.
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2001: Salazar O; Molitor J; Lienqueo M E; Asenjo J A
Overproduction, purification, and characterization of beta-1,3-glucanase type II in Escherichia coli.
Protein expression and purification 2001;23(2):219-25.
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2001: Pinto J M; Montagna J M; Vecchietti A R; Iribarren O A; Asenjo J A
Process performance models in the optimization of multiproduct protein production plants.
Biotechnology and bioengineering 2001;74(6):451-65.
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2001: Gonzalez R; Andrews B A; Asenjo J A
Metabolic control analysis of monoclonal antibody synthesis.
Biotechnology progress 2001;17(2):217-26.
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2001: Salamanca M H; Barría C; Asenjo J A; Andrews B A
Isolation, purification and preliminary characterization of cryophilic proteases of marine origin.
Bioseparation 2001;10(4-5):237-41.
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2000: Taboada M E; Graber T A; Asenjo J A; Andrews B A
Drowning-out crystallisation of sodium sulphate using aqueous two-phase systems.
Journal of chromatography. B, Biomedical sciences and applications 2000;743(1-2):101-5.
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2000: Graber T A; Andrews B A; Asenjo J A
Model for the partition of metal ions in aqueous two-phase systems.
Journal of chromatography. B, Biomedical sciences and applications 2000;743(1-2):57-64.
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2000: Montagna J M; Vecchietti A R; Iribarren O A; Pinto J M; Asenjo J A
Optimal design of protein production plants with time and size factor process models.
Biotechnology progress 2000;16(2):228-37.
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1998: Salamanca M H; Merchuk J C; Andrews B A; Asenjo J A
On the kinetics of phase separation in aqueous two-phase systems.
Journal of chromatography. B, Biomedical sciences and applications 1998;711(1-2):319-29.
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1998: Merchuk J C; Andrews B A; Asenjo J A
Aqueous two-phase systems for protein separation. Studies on phase inversion.
Journal of chromatography. B, Biomedical sciences and applications 1998;711(1-2):285-93.
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1998: Ferrer P; Diers I; Asenjo J A; Andrews B A
Yeast cell permeabilizing beta-1,3-glucanases: A tool for the integration of downstream processes and metabolic engineering applications to yeast.
Biotechnology and bioengineering 1998;58(2-3):321-4.
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1996: Andrews B A; Asenjo J A
Protein partitioning equilibrium between the aqueous poly(ethylene glycol) and salt phases and the solid protein phase in poly(ethylene glycol)-salt two-phase systems.
Journal of chromatography. B, Biomedical applications 1996;685(1):15-20.
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1996: Parrado J; Escuredo P R; Conejero-Lara F; Kotik M; Ponting C P; Asenjo J A; Dobson C M
Molecular characterisation of a thermoactive beta-1,3-glucanase from Oerskovia xanthineolytica.
Biochimica et biophysica acta 1996;1296(2):145-51.
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1996: Ferrer P; Halkier T; Hedegaard L; Savva D; Diers I; Asenjo J A
Nucleotide sequence of a beta-1,3-glucanase isoenzyme IIA gene of Oerskovia xanthineolytica LL G109 (Cellulomonas cellulans) and initial characterization of the recombinant enzyme expressed in Bacillus subtilis.
Journal of bacteriology 1996;178(15):4751-7.
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1996: Schmidt A S; Andrews B A; Asenjo J A
Correlations for the partition behavior of proteins in aqueous two-phase systems: Effect of overall protein concentration.
Biotechnology and bioengineering 1996;50(6):617-26.
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1996: Ferrer P; Hedegaard L; Halkier T; Diers I; Savva D; Asenjo J A
Molecular cloning of a lytic beta-1,3-glucanase gene from Oerskovia xanthineolytica LLG109. A beta-1,3-glucanase able to selectively permeabilize the yeast cell wall.
Annals of the New York Academy of Sciences 1996;782():555-65.
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1996: Leser E W; Lienqueo M E; Asenjo J A
Implementation in an expert system of a selection rationale for purification processes for recombinant proteins.
Annals of the New York Academy of Sciences 1996;782():441-55.
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1996: Regalado C; Asenjo J A; Pyle D L
Studies on the purification of peroxidase from horseradish roots using reverse micelles.
Enzyme and microbial technology 1996;18(5):332-9.
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1996: Franco T T; Andrews A T; Asenjo J A
Use of chemically modified proteins to study the effect of a single protein property on partitioning in aqueous two-phase systems: Effect of surface charge.
Biotechnology and bioengineering 1996;49(3):309-15.
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1996: Franco T T; Andrews A T; Asenjo J A
Use of chemically modified proteins to study the effect of a single protein property on partitioning in aqueous two-phase systems: Effect of surface hydrophobicity.
Biotechnology and bioengineering 1996;49(3):300-8.
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1996: Franco T T; Andrews A T; Asenjo J A
Conservative chemical modification of proteins to study the effects of a single protein property on partitioning in aqueous two-phase systems.
Biotechnology and bioengineering 1996;49(3):290-9.
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1996: Andrews B A; Nielsen S; Asenjo J A
Partitioning and purification of monoclonal antibodies in aqueous two-phase systems.
Bioseparation 1996;6(5):303-13.
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1995: Andrews B A; Huang R B; Asenjo J A
Purification of virus like particles from yeast cells using aqueous two-phase systems.
Bioseparation 1995;5(2):105-12.
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1995: Merchuk J C; Asenjo J A
Fundamentals of bioreactor design.
Bioprocess technology 1995;21():139-205.
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1994: Watanabe E; Tsoka S; Asenjo J A
Selection of chromatographic protein purification operations based on physicochemical properties.
Annals of the New York Academy of Sciences 1994;721():348-64.
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1994: Leser E W; Asenjo J A
The rational selection of purification processes for proteins: an expert system for downstream processing design.
Annals of the New York Academy of Sciences 1994;721():337-47.
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1994: Asenjo J A; Turner R E; Mistry S L; Kaul A
Separation and purification of recombinant proteins from Escherichia coli with aqueous two-phase systems.
Journal of chromatography. A 1994;668(1):129-37.
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1994: Leser E W; Asenjo J A
Protein recovery, separation and purification. Selection of optimal techniques using an expert system.
Memórias do Instituto Oswaldo Cruz 1994;89(1):99-109.
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1993: Asenjo J A; Ventom A M; Huang R B; Andrews B A
Selective release of recombinant protein particles (VLPs) from yeast using a pure lytic glucanase enzyme.
Bio/technology (Nature Publishing Company) 1993;11(2):214-7.
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1992: Leser E W; Asenjo J A
Rational design of purification processes for recombinant proteins.
Journal of chromatography 1992;584(1):43-57.
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1992: Mistry S L; Asenjo J A; Zaror C A
Mathematical modelling and simulation of aqueous two-phase continuous protein extraction.
Bioseparation 1992;3(6):343-58.
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1991: Asenjo J A; Parrado J; Andrews B A
Rational design of purification processes for recombinant proteins.
Annals of the New York Academy of Sciences 1991;646():334-56.
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1991: Lye G J; Asenjo J A; Pyle L
Mass transfer studies on the extraction and separation of proteins using reverse micelles.
Biochemical Society transactions 1991;19(3):275S.
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1990: Asenjo J A
Selection of operations in separation processes.
Bioprocess technology 1990;9():3-16.
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1990: Asenjo J A; Andrews B A
Enzymatic cell lysis for product release.
Bioprocess technology 1990;9():143-75.
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1988: Asenjo J A; Andrews B A; Pitts J M
Design of enzyme systems for selective product release from microbial cells; isolation of a recombinant protein from yeast.
Annals of the New York Academy of Sciences 1988;542():140-52.
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1987: Andrews B A; Asenjo J A
Production of enzyme systems in continuous culture for the controlled lysis of microbial cells.
Annals of the New York Academy of Sciences 1987;506():637-41.
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