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Andrew Heath

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TOP 3
Jennifer Carlring; Evy De Leenheer; Robert Dickinson; Marika J Szabo; Andrew W Heath
Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.
James B Wing; Jennifer Carlring; Rachel A Foster; Andrew Lees; Robert C Read; Lynne Smart; Ray Borrow; Helen Findlow; Jamie Findlow; Andrew W Heath
Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity.
James B Wing; Lynne Smart; Ray Borrow; Jamie Findlow; Helen Findlow; Andrew W Heath; Robert C Read
Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination.

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All Publications

2012: Jennifer Carlring; Evy De Leenheer; Robert Dickinson; Marika J Szabo; Andrew W Heath
Conjugation of lymphoma idiotype to CD40 antibody enhances lymphoma vaccine immunogenicity and antitumor effects in mice.
Blood 2012;119(9):2056-65.
2012: James B Wing; Jennifer Carlring; Rachel A Foster; Andrew Lees; Robert C Read; Lynne Smart; Ray Borrow; Helen Findlow; Jamie Findlow; Andrew W Heath
Correlation of group C meningococcal conjugate vaccine response with B- and T-lymphocyte activity.
PloS one 2012;7(2):e31160.
2011: James B Wing; Lynne Smart; Ray Borrow; Jamie Findlow; Helen Findlow; Andrew W Heath; Robert C Read
Kinetics of immune responses to nasal challenge with meningococcal polysaccharide one year after serogroup-C glycoconjugate vaccination.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(11):1317-23.
2011: Tom C Darton; James B Wing; Andrew Lees; Andrew W Heath; Robert C Read
Adult survivors of invasive pneumococcal disease exhibit defective B cell function.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2011;52(9):1133-6.
2011: Jennifer Carlring; Evy De Leenheer; Andrew W Heath
A novel redox method for rapid production of functional bi-specific antibodies for use in early pilot studies.
PloS one 2011;6(7):e22533.
2010: Rachel A Foster; Jennifer Carlring; Andrew Lees; Ray Borrow; Mary Ramsay; Ed Kacsmarski; Elizabeth Miller; Michael W McKendrick; Andrew W Heath; Robert C Read
Functional T-cell deficiency in adolescents who experience serogroup C meningococcal disease despite receiving the meningococcal serogroup C conjugate vaccine.
Clinical and vaccine immunology : CVI 2010;17(7):1104-10.
2010: Nima Rezaei; James B Wing; Asghar Aghamohammadi; Jennifer Carlring; Andrew Lees; Hossein Asgarian-Omran; Zahra Pourpak; Abdolfattah Sarrafnejad; Gholam A Kardar; Tahereh Shahrestani; Farimah Masoumi; Ahad Zare; Shiva Saghafi; Shokouh Sarrafzadeh; Rachel A Foster; Andrew W Heath; Robert C Read
B-cell-T-cell activation and interaction in common variable immunodeficiency.
Human immunology 2010;71(4):355-62.
2010: Vijay Ns Bhagawati-Prasad; Evy De Leenheer; Nadine P Keefe; Lorna A Ryan; Jennifer Carlring; Andrew W Heath
CD40mAb adjuvant induces a rapid antibody response that may be beneficial in post-exposure prophylaxis.
Journal of immune based therapies and vaccines 2010;8():1.
2009: Rachel A Foster; Jennifer Carlring; Michael W McKendrick; Andrew Lees; Ray Borrow; Robert C Read; Andrew W Heath
Evidence of a functional B-cell immunodeficiency in adults who experience serogroup C meningococcal disease.
Clinical and vaccine immunology : CVI 2009;16(5):692-8.
2007: Caterina Hatzifoti; Andrew W Heath
CD40-mediated enhancement of immune responses against three forms of influenza vaccine.
Immunology 2007;122(1):98-106.
2007: Sonali Nimal; Mark S Thomas; Andrew W Heath
Fusion of antigen to Fas-ligand in a DNA vaccine enhances immunogenicity.
Vaccine 2007;25(12):2306-15.
2006: Tom Barr; Jennifer Carlring; Andrew W Heath
Co-stimulatory agonists as immunological adjuvants.
Vaccine 2006;24(17):3399-407.
2006: Tom Barr; Jennifer Carlring; Caterina Hatzifoti; Andrew W Heath
Antibodies against cell surface antigens as very potent immunological adjuvants.
Vaccine 2006;24 Suppl 2():S2-20-1.
2006: Sonali Nimal; Andrew W Heath; Mark S Thomas
Enhancement of immune responses to an HIV gp120 DNA vaccine by fusion to TNF alpha cDNA.
Vaccine 2006;24(16):3298-308.
2005: Sonali Nimal; Adele L McCormick; Mark S Thomas; Andrew W Heath
An interferon gamma-gp120 fusion delivered as a DNA vaccine induces enhanced priming.
Vaccine 2005;23(30):3984-90.
2005: Tom Barr; Jennifer Carlring; Andrew W Heath
CD40 antibody as a potent immunological adjuvant: CD40 antibody provides the CD40 signal to B cells, but does not substitute for T cell help in responses to TD antigens.
Vaccine 2005;23(26):3477-82.
2005: Jennifer Cairing; Tom Barr; Andrew W Heath
Adjuvanticity of anti-cD40 in vaccine development.
Current opinion in molecular therapeutics 2005;7(1):73-7.
2004: Jennifer Carlring; Tom Barr; Adele L McCormick; Andrew W Heath
CD40 antibody as an adjuvant induces enhanced T cell responses.
Vaccine 2004;22(25-26):3323-8.
2003: Tom Barr; Adele L McCormick; Jennifer Carlring; Andrew W Heath
A potent adjuvant effect of CD40 antibody attached to antigen.
Immunology 2003;109(1):87-92.
2003: Jennifer Carlring; Tom Barr; Anne-Marie Buckle; Andrew W Heath
Anti-CD28 has a potent adjuvant effect on the antibody response to soluble antigens mediated through CTLA-4 by-pass.
European journal of immunology 2003;33(1):135-42.
2002: John R Simms; Roy Jennings; Vernon J Richardson; Andrew W Heath
Large-scale comparison of experimental adjuvants with herpes simplex virus vaccine reveals a correlation of protection with IgG2a and IgG2b responses.
Journal of medical virology 2002;68(1):82-91.
2001: Adele L McCormick; Mark S Thomas; Andrew W Heath
Immunization with an interferon-gamma-gp120 fusion protein induces enhanced immune responses to human immunodeficiency virus gp120.
The Journal of infectious diseases 2001;184(11):1423-30.
2001: Andrew W Heath
Recent advances in vaccinology.
Current opinion in pharmacology 2001;1(4):425-30.
2001: SA Mohamedi; Andrew W Heath; Roy Jennings
A comparison of oral and parenteral routes for therapeutic vaccination with HSV-2 ISCOMs in mice; cytokine profiles, antibody responses and protection.
Antiviral research 2001;49(2):83-99.
2001: Tom Barr; Andrew W Heath
Functional activity of CD40 antibodies correlates to the position of binding relative to CD154.
Immunology 2001;102(1):39-43.
2000: SA Mohamedi; J M Brewer; J Alexander; Andrew W Heath; Roy Jennings
Antibody responses, cytokine levels and protection of mice immunised with HSV-2 antigens formulated into NISV or ISCOM delivery systems.
Vaccine 2000;18(20):2083-94.
2000: John R Simms; Andrew W Heath; Roy Jennings
Use of herpes simplex virus (HSV) type 1 ISCOMS 703 vaccine for prophylactic and therapeutic treatment of primary and recurrent HSV-2 infection in guinea pigs.
The Journal of infectious diseases 2000;181(4):1240-8.
2000: SA Mohamedi; Andrew W Heath; Roy Jennings
Therapeutic vaccination against HSV-2: influence of vaccine formulation on immune responses and protection in mice.
Vaccine 2000;18(17):1778-92.
1999: Adele L McCormick; Leopoldo Santos-Argumedo; Mark S Thomas; Andrew W Heath
Cell surface expression of CD154 inhibits alloantibody responses: A mechanism for the prevention of autoimmune responses against activated T cells?
Cellular immunology 1999;195(2):157-61.
1999: Tom Barr; Andrew W Heath
Enhanced in vivo immune responses to bacterial lipopolysaccharide by exogenous CD40 stimulation.
Infection and immunity 1999;67(7):3637-40.
1998: Troy D Randall; Andrew W Heath; Leopoldo Santos-Argumedo; MC Howard; I L Weissman; Frances E Lund
Arrest of B lymphocyte terminal differentiation by CD40 signaling: mechanism for lack of antibody-secreting cells in germinal centers.
Immunity 1998;8(6):733-42.
1998: John R Simms; Andrew W Heath; Vernon J Richardson; Roy Jennings
Humoral response to HSV-1 subunit vaccines--a statistical analysis.
Developments in biological standardization 1998;92():335-40.
1998: Per A Dullforce; D Sutton; Andrew W Heath
A novel method for enhancement of T independent responses.
Developments in biological standardization 1998;92():195-8.
1998: Roy Jennings; John R Simms; Andrew W Heath
Adjuvants and delivery systems for viral vaccines--mechanisms and potential.
Developments in biological standardization 1998;92():19-28.
1998: Per A Dullforce; D C Sutton; Andrew W Heath
Enhancement of T cell-independent immune responses in vivo by CD40 antibodies.
Nature medicine 1998;4(1):88-91.
1997: Adele L McCormick; Mark S Thomas; Andrew W Heath
Enhancement of immunogenicity of recombinant antigens by production of a cytokine-antigen fusion protein for vaccination.
Biochemical Society transactions 1997;25(2):297S.
1997: John R Simms; Andrew W Heath; Vernon J Richardson; Roy Jennings
Large scale comparison of adjuvant effects on immunogenicity and protection in a herpes simplex virus type 1 vaccination model.
Biochemical Society transactions 1997;25(2):272S.
1996: W G Ferlin; Eva Severinson; L Ström; Andrew W Heath; Robert L Coffman; D A Ferrick; MC Howard
CD40 signaling induces interleukin-4-independent IgE switching in vivo.
European journal of immunology 1996;26(12):2911-5.
1996: B Garcia; R Rodríguez; I Angulo; Andrew W Heath; MC Howard; JL Subiza
Differential effects of transforming growth factor-beta 1 on IgA vs. IgG2b production by lipopolysaccharide-stimulated lymph node B cells: a comparative study with spleen B cells.
European journal of immunology 1996;26(10):2364-70.
1995: Leopoldo Santos-Argumedo; Frances E Lund; Andrew W Heath; N Solvason; W W Wu; J C Grimaldi; R M Parkhouse; M Howard
CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regular of CD38 induced signal transduction.
International immunology 1995;7(2):163-70.
1995: Andrew W Heath
Cytokines as adjuvants in immunocompromised hosts.
International journal of clinical & laboratory research 1995;25(1):25-8.
1995: Andrew W Heath
Cytokines as immunological adjuvants.
Pharmaceutical biotechnology 1995;6():645-58.
1994: Andrew W Heath; W W Wu; MC Howard
Monoclonal antibodies to murine CD40 define two distinct functional epitopes.
European journal of immunology 1994;24(8):1828-34.
1994: Leopoldo Santos-Argumedo; J Gordon; Andrew W Heath; M Howard
Antibodies to murine CD40 protect normal and malignant B cells from induced growth arrest.
Cellular immunology 1994;156(2):272-85.
1993: Andrew W Heath; R Chang; N Harada; Leopoldo Santos-Argumedo; J Gordon; C Hannum; D Campbell; A B Shanafelt; E A Clark; R Torres
Antibodies to murine CD40 stimulate normal B lymphocytes but inhibit proliferation of B lymphoma cells.
Cellular immunology 1993;152(2):468-80.
1993: N Harada; Leopoldo Santos-Argumedo; R Chang; J C Grimaldi; Frances E Lund; C I Brannan; N G Copeland; N A Jenkins; Andrew W Heath; R M Parkhouse
Expression cloning of a cDNA encoding a novel murine B cell activation marker. Homology to human CD38.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(6):3111-8.
1992: Andrew W Heath; J H Playfair
The potential of cytokines as adjuvants.
AIDS research and human retroviruses 1992;8(8):1401-3.