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Mary Hebert

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Mary F Hebert; Menachem Miodovnik; Danny D Shen; Kenneth E Thummel; Jason G Umans; Songmao Zheng; Connie L Davis; Karen Hays; Thomas R Easterling
Interpreting tacrolimus concentrations during pregnancy and postpartum.
Songmao Zheng; Justina C Calamia; Connie L Davis; Mary F Hebert; Yvonne S Lin; Danny D Shen; Yoshihisa Shitara; Yasar Tasnif; Kenneth E Thummel
CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition.
Diana L Shuster; Kenneth E Thummel; Jesse M Tsai; Theo K Bammler; Richard P Beyer; Frederico M Farin; Mary F Hebert; James W Macdonald; Qingcheng Mao
Gestational age-dependent changes in gene expression of metabolic enzymes and transporters in pregnant mice.

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2013: Mary F Hebert; Menachem Miodovnik; Danny D Shen; Kenneth E Thummel; Jason G Umans; Songmao Zheng; Connie L Davis; Karen Hays; Thomas R Easterling
Interpreting tacrolimus concentrations during pregnancy and postpartum.
Transplantation 2013;95(7):908-15.
2013: Songmao Zheng; Justina C Calamia; Connie L Davis; Mary F Hebert; Yvonne S Lin; Danny D Shen; Yoshihisa Shitara; Yasar Tasnif; Kenneth E Thummel
CYP3A5 gene variation influences cyclosporine A metabolite formation and renal cyclosporine disposition.
Transplantation 2013;95(6):821-7.
2013: Diana L Shuster; Kenneth E Thummel; Jesse M Tsai; Theo K Bammler; Richard P Beyer; Frederico M Farin; Mary F Hebert; James W Macdonald; Qingcheng Mao
Gestational age-dependent changes in gene expression of metabolic enzymes and transporters in pregnant mice.
Drug metabolism and disposition: the biological fate of chemicals 2013;41(2):332-42.
2012: S Zheng; Justina C Calamia; C L Davis; Mary F Hebert; Yvonne S Lin; Danny D Shen; Y Shitara; Y Tasnif; Kenneth E Thummel
Measurement and compartmental modeling of the effect of CYP3A5 gene variation on systemic and intrarenal tacrolimus disposition.
Clinical pharmacology and therapeutics 2012;92(6):737-45.
2012: Songmao Zheng; Justina C Calamia; Connie L Davis; Thomas R Easterling; Menachem Miodovnik; Danny D Shen; Kenneth E Thummel; Jason G Umans; Mary F Hebert
Pharmacokinetics of tacrolimus during pregnancy.
Therapeutic drug monitoring 2012;34(6):660-70.
2012: Zhican Wang; Xi Emily Zheng; Thomas A Baillie; David Blough; Connie L Davis; Leslie J Dickmann; Takanori Hashizume; Mary F Hebert; Yvonne S Lin; Sidney D Nelson; Michele Scian; T Senn; Kenneth E Thummel
An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway.
Molecular pharmacology 2012;81(4):498-509.
2011: Zhican Wang; Songmao Zheng; Xi Emily Zheng; Connie L Davis; Mary F Hebert; Thomas F Kalhorn; Yvonne S Lin; T Senn; Kenneth E Thummel
Simultaneous measurement of plasma vitamin D(3) metabolites, including 4β,25-dihydroxyvitamin D(3), using liquid chromatography-tandem mass spectrometry.
Analytical biochemistry 2011;418(1):126-33.
2010: Sara Eyal; Joong D Kim; Gail D Anderson; Megan L Buchanan; Debra A Brateng; Darcy Carr; David E Woodrum; Thomas R Easterling; Mary F Hebert
Atenolol pharmacokinetics and excretion in breast milk during the first 6 to 8 months postpartum.
Journal of clinical pharmacology 2010;50(11):1301-9.
2010: Lin Zhou; Yi Zhang; Mary F Hebert; Jashvant D Unadkat; Qingcheng Mao
Increased glyburide clearance in the pregnant mouse model.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(9):1403-6.
2010: Lin Zhou; Suresh B Naraharisetti; Li Liu; Honggang Wang; Yvonne S Lin; Nina Isoherranen; Jashvant D Unadkat; Mary F Hebert; Qingcheng Mao
Contributions of human cytochrome P450 enzymes to glyburide metabolism.
Biopharmaceutics & drug disposition 2010;31(4):228-42.
2010: Sara Eyal; Thomas R Easterling; Darcy Carr; Jason G Umans; Menachem Miodovnik; Gary D V Hankins; Shannon M Clark; Linda Risler; Joanne Wang; Edward J Kelly; Danny D Shen; Mary F Hebert
Pharmacokinetics of metformin during pregnancy.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(5):833-40.
2009: Sara Eyal; Francisco S Chung; Mark Muzi; Jeanne M Link; David A Mankoff; Amal Kaddoumi; Finbarr O'Sullivan; Mary F Hebert; Jashvant D Unadkat
Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant nonhuman primate.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):798-806.
2009: M L Buchanan; T R Easterling; D B Carr; Danny D Shen; Linda Risler; Wendel L Nelson; Donald R Mattison; Mary F Hebert
Clonidine pharmacokinetics in pregnancy.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(4):702-5.
2008: Andrei M Mikheev; Tomo NABEKURA; Amal Kaddoumi; Theo K Bammler; Rajgopal Govindarajan; Mary F Hebert; Jashvant D Unadkat
Profiling gene expression in human placentae of different gestational ages: an OPRU Network and UW SCOR Study.
Reproductive sciences (Thousand Oaks, Calif.) 2008;15(9):866-77.
2008: Mary F Hebert; Thomas R Easterling; B Kirby; Daniel B Carr; M L Buchanan; T Rutherford; Kenneth E Thummel; D P Fishbein; J D Unadkat
Effects of pregnancy on CYP3A and P-glycoprotein activities as measured by disposition of midazolam and digoxin: a University of Washington specialized center of research study.
Clinical pharmacology and therapeutics 2008;84(2):248-53.
2008: Leslie J Dickmann; Suzanne Tay; Tauri D Senn; Huixia Zhang; Anthony Visone; Jashvant D Unadkat; Mary F Hebert; Nina Isoherranen
Changes in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancy.
Biochemical pharmacology 2008;75(8):1677-87.
2008: Lin Zhou; Suresh B Naraharisetti; Honggang Wang; Jashvant D Unadkat; Mary F Hebert; Qingcheng Mao
The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study.
Molecular pharmacology 2008;73(3):949-59.
2008: Marilee A Andrew; Mary F Hebert; Paolo Vicini
Physiologically based pharmacokinetic model of midazolam disposition during pregnancy.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2008;2008():5454-7.
2007: Suresh B Naraharisetti; Brian J Kirby; Mary F Hebert; Thomas R Easterling; Jashvant D Unadkat
Validation of a sensitive LC-MS assay for quantification of glyburide and its metabolite 4-transhydroxy glyburide in plasma and urine: an OPRU Network study.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2007;860(1):34-41.
2006: Anshul Gupta; Yang Dai; R Robert Vethanayagam; Mary F Hebert; Kenneth E Thummel; Jashvant D Unadkat; Douglas Ross; Qingcheng Mao
Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan.
Cancer chemotherapy and pharmacology 2006;58(3):374-83.
2006: Yang Dai; Mary F Hebert; Nina Isoherranen; Connie L Davis; Christopher Marsh; Danny D Shen; Kenneth E Thummel
Effect of CYP3A5 polymorphism on tacrolimus metabolic clearance in vitro.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(5):836-47.
2005: Mary F Hebert; Helen E Smith; Thomas C Marbury; Suzanne K Swan; William B Smith; Robert W Townsend; Donald N Buell; James Keirns; Ihor Bekersky
Pharmacokinetics of micafungin in healthy volunteers, volunteers with moderate liver disease, and volunteers with renal dysfunction.
Journal of clinical pharmacology 2005;45(10):1145-52.
2005: Mary F Hebert; David K Blough; Robert W Townsend; Mark Allison; Donald N Buell; James Keirns; Ihor Bekersky
Concomitant tacrolimus and micafungin pharmacokinetics in healthy volunteers.
Journal of clinical pharmacology 2005;45(9):1018-24.
2005: Mary F Hebert; Robert W Townsend; Stephen Austin; Guhan Balan; David K Blough; Donald N Buell; James Keirns; Ihor Bekersky
Concomitant cyclosporine and micafungin pharmacokinetics in healthy volunteers.
Journal of clinical pharmacology 2005;45(8):954-60.
2005: Mary F Hebert; Darcy B Carr; Gail D Anderson; David K Blough; Grace E Green; Debra A Brateng; Eric D Kantor; Thomas J Benedetti; Thomas R Easterling
Pharmacokinetics and pharmacodynamics of atenolol during pregnancy and postpartum.
Journal of clinical pharmacology 2005;45(1):25-33.
2004: Yang Dai; Kazunori Iwanaga; Yvonne S Lin; Mary F Hebert; Connie L Davis; Weili Huang; Evan D Kharasch; Kenneth E Thummel
In vitro metabolism of cyclosporine A by human kidney CYP3A5.
Biochemical pharmacology 2004;68(9):1889-902.
2004: Mary F Hebert; Jeong M Park; Yu-Luan Chen; Shahzad Akhtar; Anne M Larson
Effects of St. John's wort (Hypericum perforatum) on tacrolimus pharmacokinetics in healthy volunteers.
Journal of clinical pharmacology 2004;44(1):89-94.
2003: Mary F Hebert; Amy L Dowling; Cynthia Gierwatowski; Yvonne S Lin; Karen L Edwards; Connie L Davis; Christopher L Marsh; Erin G Schuetz; Kenneth E Thummel
Association between ABCB1 (multidrug resistance transporter) genotype and post-liver transplantation renal dysfunction in patients receiving calcineurin inhibitors.
Pharmacogenetics 2003;13(11):661-74.
2003: Jeong M Park; Yvonne S Lin; Justina C Calamia; Kenneth E Thummel; John T Slattery; Thomas F Kalhorn; Robert L Carithers; Adam E Levy; Christopher L Marsh; Mary F Hebert
Transiently altered acetaminophen metabolism after liver transplantation.
Clinical pharmacology and therapeutics 2003;73(6):545-53.
2003: Mary F Hebert; Vincent J Wacher; John P Roberts; Leslie Z Benet
Pharmacokinetics of cyclosporine pre- and post-liver transplantation.
Journal of clinical pharmacology 2003;43(1):38-42.
1999: Mary F Hebert; R M Fisher; Christopher L Marsh; D Dressler; Ihor Bekersky
Effects of rifampin on tacrolimus pharmacokinetics in healthy volunteers.
Journal of clinical pharmacology 1999;39(1):91-6.