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Stefan Hecht

Research Profile

Chemicals & Drugs

Concepts & Ideas

Living Beings

Escherichia coli

Genes & Molecular Sequences

Amino Acid Sequences

Phenomena

Procedures

Nuclear Magnetic Resonance, Biomolecular

Co-author Network

Publications

TOP 3
Sabine Amslinger; Stefan Hecht; Felix Rohdich; Wolfgang Eisenreich; Petra Adam; Adelbert Bacher; Stefan Bauer
Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate.
Lauris E Kemp; Magnus S Alphey; Charles Bond; Michael A J Ferguson; Stefan Hecht; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich; William N Hunter
The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.
Mads Gabrielsen; Charles Bond; Irene Hallyburton; Stefan Hecht; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich; William N Hunter
Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis.

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All Publications

2007: Sabine Amslinger; Stefan Hecht; Felix Rohdich; Wolfgang Eisenreich; Petra Adam; Adelbert Bacher; Stefan Bauer
Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate.
Immunobiology 2007;212(1):47-55.
2005: Lauris E Kemp; Magnus S Alphey; Charles Bond; Michael A J Ferguson; Stefan Hecht; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich; William N Hunter
The identification of isoprenoids that bind in the intersubunit cavity of Escherichia coli 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase by complementary biophysical methods.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 1):45-52.
2004: Mads Gabrielsen; Charles Bond; Irene Hallyburton; Stefan Hecht; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich; William N Hunter
Hexameric assembly of the bifunctional methylerythritol 2,4-cyclodiphosphate synthase and protein-protein associations in the deoxy-xylulose-dependent pathway of isoprenoid precursor biosynthesis.
The Journal of biological chemistry 2004;279(50):52753-61.
2004: Tobias Gräwert; Johannes Kaiser; Ferdinand Zepeck; Ralf Laupitz; Stefan Hecht; Sabine Amslinger; Nicholas Schramek; Erik Schleicher; Stefan Weber; Martin Haslbeck; Johannes Buchner; Christoph Rieder; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich
IspH protein of Escherichia coli: studies on iron-sulfur cluster implementation and catalysis.
Journal of the American Chemical Society 2004;126(40):12847-55.
2004: Mads Gabrielsen; Felix Rohdich; Wolfgang Eisenreich; Tobias Gräwert; Stefan Hecht; Adelbert Bacher; William N Hunter
Biosynthesis of isoprenoids: a bifunctional IspDF enzyme from Campylobacter jejuni.
European journal of biochemistry / FEBS 2004;271(14):3028-35.
2004: Ralf Laupitz; Stefan Hecht; Sabine Amslinger; Ferdinand Zepeck; Johannes Kaiser; Gerald Richter; Nicholas Schramek; Stefan Steinbacher; Robert Huber; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways.
European journal of biochemistry / FEBS 2004;271(13):2658-69.
2004: Stefan Hecht; Klaus Kammhuber; Josef Reiner; Adelbert Bacher; Wolfgang Eisenreich
Biosynthetic experiments with tall plants under field conditions. 18O2 incorporation into humulone from Humulus lupulus.
Phytochemistry 2004;65(8):1057-60.
2003: linda miallau; Magnus S Alphey; Lauris E Kemp; Gordon A Leonard; Sean McSweeney; Stefan Hecht; Adelbert Bacher; Wolfgang Eisenreich; Felix Rohdich; William N Hunter
Biosynthesis of isoprenoids: crystal structure of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9173-8.
2003: Felix Rohdich; Ferdinand Zepeck; Petra Adam; Stefan Hecht; Johannes Kaiser; Ralf Laupitz; Tobias Gräwert; Sabine Amslinger; Wolfgang Eisenreich; Adelbert Bacher; Duilio Arigoni
The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1586-91.
2002: Petra Adam; Stefan Hecht; Wolfgang Eisenreich; Johannes Kaiser; Tobias Grawert; Duilio Arigoni; Adelbert Bacher; Felix Rohdich
Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12108-13.
2002: Sabine Amslinger; Klaus Kis; Stefan Hecht; Petra Adam; Felix Rohdich; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich
Biosynthesis of terpenes. Preparation of (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate, an intermediate of the deoxyxylulose phosphate pathway.
The Journal of organic chemistry 2002;67(13):4590-4.
2002: Stefan Steinbacher; Johannes Kaiser; Juraithip Wungsintaweekul; Stefan Hecht; Wolfgang Eisenreich; Stefan Gerhardt; Adelbert Bacher; Felix Rohdich
Structure of 2C-methyl-d-erythritol-2,4-cyclodiphosphate synthase involved in mevalonate-independent biosynthesis of isoprenoids.
Journal of molecular biology 2002;316(1):79-88.
2002: Felix Rohdich; Stefan Hecht; Katrin Gärtner; Petra Adam; Cornelia Krieger; Sabine Amslinger; Duilio Arigoni; Adelbert Bacher; Wolfgang Eisenreich
Studies on the nonmevalonate terpene biosynthetic pathway: metabolic role of IspH (LytB) protein.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(3):1158-63.
2001: Stefan Hecht; Wolfgang Eisenreich; Petra Adam; Sabine Amslinger; Klaus Kis; Adelbert Bacher; Duilio Arigoni; Felix Rohdich
Studies on the nonmevalonate pathway to terpenes: the role of the GcpE (IspG) protein.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):14837-42.
2001: Monika Fellermeier; Maja Raschke; Silvia Sagner; Juraithip Wungsintaweekul; Christoph A Schuhr; Stefan Hecht; Klaus Kis; Tanja Radykewicz; Petra Adam; Felix Rohdich; Wolfgang Eisenreich; Adelbert Bacher; Duilio Arigoni; Meinhart H Zenk
Studies on the nonmevalonate pathway of terpene biosynthesis. The role of 2C-methyl-D-erythritol 2,4-cyclodiphosphate in plants.
European journal of biochemistry / FEBS 2001;268(23):6302-10.
2001: Stefan Hecht; Juraithip Wungsintaweekul; Felix Rohdich; Klaus Kis; Tanja Radykewicz; Christoph A Schuhr; Wolfgang Eisenreich; Gerald Richter; Adelbert Bacher
Biosynthesis of terpenoids: efficient multistep biotransformation procedures affording isotope-labeled 2C-methyl-D-erythritol 4-phosphate using recombinant 2C-methyl-D-erythritol 4-phosphate synthase.
The Journal of organic chemistry 2001;66(23):7770-5.
2001: Felix Rohdich; Wolfgang Eisenreich; Juraithip Wungsintaweekul; Stefan Hecht; Christoph A Schuhr; Adelbert Bacher
Biosynthesis of terpenoids. 2C-Methyl-D-erythritol 2,4-cyclodiphosphate synthase (IspF) from Plasmodium falciparum.
European journal of biochemistry / FEBS 2001;268(11):3190-7.
2001: Stefan Hecht; Klaus Kis; Wolfgang Eisenreich; Sabine Amslinger; Juraithip Wungsintaweekul; Stefan Herz; Felix Rohdich; Adelbert Bacher
Enzyme-assisted preparation of isotope-labeled 1-deoxy-d-xylulose 5-phosphate.
The Journal of organic chemistry 2001;66(11):3948-52.
2001: Juraithip Wungsintaweekul; Stefan Herz; Stefan Hecht; Wolfgang Eisenreich; Richard Feicht; Felix Rohdich; Adelbert Bacher; Meinhart H Zenk
Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli.
European journal of biochemistry / FEBS 2001;268(2):310-6.
2000: Felix Rohdich; Juraithip Wungsintaweekul; Wolfgang Eisenreich; Gerald Richter; Christoph A Schuhr; Stefan Hecht; Meinhart H Zenk; Adelbert Bacher
Biosynthesis of terpenoids: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase of Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6451-6.
2000: Stefan Herz; Juraithip Wungsintaweekul; Christoph A Schuhr; Stefan Hecht; H Luttgen; Silvia Sagner; Monika Fellermeier; Wolfgang Eisenreich; Meinhart H Zenk; Adelbert Bacher; Felix Rohdich
Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2486-90.
2000: Holger Lüttgen; Felix Rohdich; Stefan Herz; Juraithip Wungsintaweekul; Stefan Hecht; Christoph A Schuhr; Monika Fellermeier; Silvia Sagner; Meinhart H Zenk; Adelbert Bacher; Wolfgang Eisenreich
Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(3):1062-7.