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Herbert Hechtman

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Herbert B Hechtman
Clinical activity and mode of action of poly-N-acetyl glucosamine fiber materials: hemostasis and wound healing. Foreword.
Saja Sandra Scherer; Giorgio Pietramaggiori; Jasmine Matthews; Samuel Perry; Anke Assmann; Adelaide Carothers; Marina Demcheva; Robin C Muise-Helmericks; Arun Seth; john vournakis; Robert C Valeri; Thomas H Fischer; Herbert B Hechtman; Dennis Orgill
Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis.
Giorgio Pietramaggiori; Ho-Jik Yang; Saja S Scherer; Arja Kaipainen; Rodney Chan; Michael Alperovich; Jennifer Newalder; Marina Demcheva; john vournakis; C Robert Valeri; Herbert B Hechtman; Dennis Orgill
Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse.

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2011: Herbert B Hechtman
Clinical activity and mode of action of poly-N-acetyl glucosamine fiber materials: hemostasis and wound healing. Foreword.
The Journal of trauma 2011;71(2 Suppl 1):S161.
2009: Saja Sandra Scherer; Giorgio Pietramaggiori; Jasmine Matthews; Samuel Perry; Anke Assmann; Adelaide Carothers; Marina Demcheva; Robin C Muise-Helmericks; Arun Seth; john vournakis; Robert C Valeri; Thomas H Fischer; Herbert B Hechtman; Dennis Orgill
Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis.
Annals of surgery 2009;250(2):322-30.
2008: Giorgio Pietramaggiori; Ho-Jik Yang; Saja S Scherer; Arja Kaipainen; Rodney Chan; Michael Alperovich; Jennifer Newalder; Marina Demcheva; john vournakis; C Robert Valeri; Herbert B Hechtman; Dennis Orgill
Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse.
The Journal of trauma 2008;64(3):803-8.
2006: Rodney Chan; Perry H Liu; Giorgio Pietramaggiori; Shahrul Ibrahim; Herbert B Hechtman; Dennis Orgill
Effect of recombinant platelet-derived growth factor (Regranex) on wound closure in genetically diabetic mice.
Journal of burn care & research : official publication of the American Burn Association 2006;27(2):202-5.
2005: Rodney Chan; Perry Liu; Dae-Hyun Lew; Shahrul Ibrahim; Rithy Srey; C Robert Valeri; Herbert B Hechtman; Dennis Orgill
Expired liquid preserved platelet releasates retain proliferative activity.
The Journal of surgical research 2005;126(1):55-8.
2004: Rodney Chan; William G Austen; Shahrul Ibrahim; Grace Y Ding; Nicola Verna; Herbert B Hechtman; Francis D Moore
Reperfusion injury to skeletal muscle affects primarily type II muscle fibers.
The Journal of surgical research 2004;122(1):54-60.
2004: Rodney Chan; Grace Ding; Nicola Verna; Shahrul Ibrahim; Sean Oakes; William G Austen; Herbert B Hechtman; Francis D Moore
IgM binding to injured tissue precedes complement activation during skeletal muscle ischemia-reperfusion.
The Journal of surgical research 2004;122(1):29-35.
2004: William G Austen; Ming Zhang; Rodney Chan; Daniel S Friend; Herbert B Hechtman; Michael C Carroll; Francis D Moore
Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM.
Surgery 2004;136(2):401-6.
2004: Joanne Favuzza; Herbert B Hechtman
Hemostasis in the absence of clotting factors.
The Journal of trauma 2004;57(1 Suppl):S42-4.
2004: Ming Zhang; William G Austen; Isaac Chiu; Elisabeth M Alicot; Rachel Hung; Minghe Ma; Nicola Verna; Min Xu; Herbert B Hechtman; Francis D Moore; Michael C Carroll
Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(11):3886-91.
2003: Rodney Chan; Shahrul Ibrahim; Nicola Verna; M Carroll; Francis D Moore; Herbert B Hechtman
Ischaemia-reperfusion is an event triggered by immune complexes and complement.
The British journal of surgery 2003;90(12):1470-8.
2003: William G Austen; Lester Kobzik; Michael C Carroll; Herbert B Hechtman; Francis D Moore
The role of complement and natural antibody in intestinal ischemia-reperfusion injury.
International journal of immunopathology and pharmacology 2003;16(1):1-8.
2002: Russell R Reid; Sean Woodcock; Alexander Shimabukuro-Vornhagen; William G Austen; Lester Kobzik; Ming Zhang; Herbert B Hechtman; Francis D Moore; Michael C Carroll
Functional activity of natural antibody is altered in Cr2-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5433-40.
2002: Wilfred Lieberthal; Robert Fuhro; Hasan Alam; Peter Rhee; Janos Szebeni; Herbert B Hechtman; Joanne Favuzza; Richard L Veech; C Robert Valeri
Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions.
Shock (Augusta, Ga.) 2002;17(1):61-9.
2001: C Kyriakides; Y Wang; William G Austen; Joanne Favuzza; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Sialyl Lewis(x) hybridized complement receptor type 1 moderates acid aspiration injury.
American journal of physiology. Lung cellular and molecular physiology 2001;281(6):L1494-9.
2001: C Robert Valeri; Gina Ragno; Linda E Pivacek; Richard C Dennis; Herbert B Hechtman; Shukri F Khuri
Survival and function of baboon RBCs released from clotted blood and washed before autologous transfusion.
Transfusion 2001;41(11):1384-9.
2001: C Robert Valeri; Richard C Dennis; Gina Ragno; Linda E Pivacek; Herbert B Hechtman; Shukri F Khuri
Survival, function, and hemolysis of shed red blood cells processed as nonwashed blood and washed red blood cells.
The Annals of thoracic surgery 2001;72(5):1598-602.
2001: MJ Lim; ET Chiang; Herbert B Hechtman; D Shepro
Inflammation-induced subcellular redistribution of VE-cadherin, actin, and gamma-catenin in cultured human lung microvessel endothelial cells.
Microvascular research 2001;62(3):366-82.
2001: C Mukundan; Michael F Gurish; K Frank Austen; Herbert B Hechtman; Daniel S Friend
Mast cell mediation of muscle and pulmonary injury following hindlimb ischemia-reperfusion.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):1055-6.
2001: C Kyriakides; William G Austen; Y Wang; Joanne Favuzza; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Mast cells mediate complement activation after acid aspiration.
Shock (Augusta, Ga.) 2001;16(1):21-4.
2001: C Kyriakides; Y Wang; William G Austen; Joanne Favuzza; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Moderation of skeletal muscle reperfusion injury by a sLe(x)-glycosylated complement inhibitory protein.
American journal of physiology. Cell physiology 2001;281(1):C224-30.
2001: C Kyriakides; Joanne Favuzza; Y Wang; William G Austen; Francis D Moore; Herbert B Hechtman
Recombinant soluble P-selectin glycoprotein ligand 1 moderates local and remote injuries following experimental lower-torso ischaemia.
The British journal of surgery 2001;88(6):825-30.
2001: C Mukundan; Michael F Gurish; K Frank Austen; Herbert B Hechtman; Daniel S Friend
The presence of v-abl-transformed V3 mast cells in the lungs augments pulmonary vascular permeability to acid aspiration.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(6):793-4.
2001: C Kyriakides; Jasleen Jasleen; Y Wang; Francis D Moore; Stanley W Ashley; Herbert B Hechtman
Neutrophils, not complement, mediate the mortality of experimental hemorrhagic pancreatitis.
Pancreas 2001;22(1):40-6.
2000: Sean Woodcock; C Kyriakides; Y Wang; William G Austen; Francis D Moore; R Valeri; D Hartwell; Herbert B Hechtman
Soluble P-selectin moderates complement dependent injury.
Shock (Augusta, Ga.) 2000;14(6):610-5.
2000: C Kyriakides; William G Austen; Y Wang; Joanne Favuzza; Francis D Moore; Herbert B Hechtman
Endothelial selectin blockade attenuates lung permeability of experimental acid aspiration.
Surgery 2000;128(2):327-31.
2000: C Kyriakides; Sean Woodcock; Y Wang; Joanne Favuzza; William G Austen; Lester Kobzik; Francis D Moore; R C Valeri; D Shepro; Herbert B Hechtman
Soluble P-selectin moderates complement-dependent reperfusion injury of ischemic skeletal muscle.
American journal of physiology. Cell physiology 2000;279(2):C520-8.
2000: Russell R Reid; Sean Woodcock; AP Prodeus; J Austen; Lester Kobzik; Herbert B Hechtman; Francis D Moore; Michael C Carroll
The role of complement receptors CD21/CD35 in positive selection of B-1 cells.
Current topics in microbiology and immunology 2000;252():57-65.
2000: C Kyriakides; William G Austen; Y Wang; Joanne Favuzza; Francis D Moore; Herbert B Hechtman
Neutrophil mediated remote organ injury after lower torso ischemia and reperfusion is selectin and complement dependent.
The Journal of trauma 2000;48(1):32-8.
1999: C Kyriakides; William G Austen; Y Wang; Joanne Favuzza; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Membrane attack complex of complement and neutrophils mediate the injury of acid aspiration.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;87(6):2357-61.
1999: C Kyriakides; William G Austen; Y Wang; Joanne Favuzza; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex.
The American journal of physiology 1999;277(6 Pt 1):C1263-8.
1999: N Shojaee; Wayne Patton; Herbert B Hechtman; D Shepro
Myosin translocation in retinal pericytes during free-radical induced apoptosis.
Journal of cellular biochemistry 1999;75(1):118-29.
1999: William G Austen; C Kyriakides; Joanne Favuzza; Y Wang; Lester Kobzik; Francis D Moore; Herbert B Hechtman
Intestinal ischemia-reperfusion injury is mediated by the membrane attack complex.
Surgery 1999;126(2):343-8.
1999: Marc R Barnard; Hollace MacGregor; R Mercier; Gina Ragno; Linda E Pivacek; Herbert B Hechtman; Alan D Michelson; C Robert Valeri
Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis.
Transfusion 1999;39(7):735-41.
1999: JP Williams; TT Pechet; Martin R Weiser; R Reid; Lester Kobzik; Francis D Moore; Michael C Carroll; Herbert B Hechtman
Intestinal reperfusion injury is mediated by IgM and complement.
Journal of applied physiology (Bethesda, Md. : 1985) 1999;86(3):938-42.
1998: BD Peyton; Michael J Rohrer; Mark I Furman; Marc R Barnard; L J Rodino; SE Benoit; Herbert B Hechtman; C R Valeri; Alan D Michelson
Patients with venous stasis ulceration have increased monocyte-platelet aggregation.
Journal of vascular surgery 1998;27(6):1109-15; discussion 1115-6.
1998: LE Hastie; Wayne Patton; Herbert B Hechtman; D Shepro
Metabolites of the phospholipase D pathway regulate H2O2-induced filamin redistribution in endothelial cells.
Journal of cellular biochemistry 1998;68(4):511-24.
1998: N Shojaee; Wayne Patton; N Chung-Welch; Q Su; Herbert B Hechtman; D Shepro
Expression and subcellular distribution of filamin isotypes in endothelial cells and pericytes.
Electrophoresis 1998;19(2):323-32.
1998: Mark I Furman; SE Benoit; Marc R Barnard; C R Valeri; M L Borbone; RC Becker; Herbert B Hechtman; Alan D Michelson
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease.
Journal of the American College of Cardiology 1998;31(2):352-8.
1997: Q Wang; Wayne Patton; Herbert B Hechtman; D Shepro
Activation of endothelial cell kinin receptors leads to intracellular calcium increases and filamin translocation: regulation by protein kinase C.
Cellular signalling 1997;9(8):595-602.
1997: JP Williams; Martin R Weiser; TT Pechet; Lester Kobzik; Francis D Moore; Herbert B Hechtman
alpha 1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat.
The American journal of physiology 1997;273(5 Pt 1):G1031-5.
1997: Martin R Weiser; TT Pechet; JP Williams; Minghe Ma; Paul S. Frenette; Francis D Moore; Lester Kobzik; R O Hines; Denisa D Wagner; Michael C Carroll; Herbert B Hechtman
Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway.
Journal of applied physiology (Bethesda, Md. : 1985) 1997;83(4):1090-5.
1997: LE Hastie; Wayne Patton; Herbert B Hechtman; D Shepro
H2O2-induced filamin redistribution in endothelial cells is modulated by the cyclic AMP-dependent protein kinase pathway.
Journal of cellular physiology 1997;172(3):373-81.
1997: Q Wang; Wayne Patton; Herbert B Hechtman; D Shepro
A novel anti-inflammatory peptide inhibits endothelial cell cytoskeletal rearrangement, nitric oxide synthase translocation, and paracellular permeability increases.
Journal of cellular physiology 1997;172(2):171-82.
1997: N M Morel; C B Xu; Herbert B Hechtman; D Shepro
Microvessel mural cell secretions modulate endothelial monolayer permeability.
Microvascular research 1997;53(2):197-200.
1997: LE Hastie; Wayne Patton; Herbert B Hechtman; D Shepro
Filamin redistribution in an endothelial cell reoxygenation injury model.
Free radical biology & medicine 1997;22(6):955-66.
1996: Q Wang; Wayne Patton; E T Chiang; Herbert B Hechtman; D Shepro
Filamin translocation is an early endothelial cell inflammatory response to bradykinin: regulation by calcium, protein kinases, and protein phosphatases.
Journal of cellular biochemistry 1996;62(3):383-96.
1996: Martin R Weiser; S A Gibbs; C R Valeri; D Shepro; Herbert B Hechtman
Anti-selectin therapy modifies skeletal muscle ischemia and reperfusion injury.
Shock (Augusta, Ga.) 1996;5(6):402-7.
1996: S A Gibbs; Martin R Weiser; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
P-selectin mediates intestinal ischemic injury by enhancing complement deposition.
Surgery 1996;119(6):652-6.
1996: Martin R Weiser; J P Williams; Francis D Moore; Lester Kobzik; Minghe Ma; Herbert B Hechtman; Michael C Carroll
Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement.
The Journal of experimental medicine 1996;183(5):2343-8.
1996: Martin R Weiser; S A Gibbs; Francis D Moore; Herbert B Hechtman
Complement inhibition by soluble complement receptor type 1 fails to moderate cerulein-induced pancreatitis in the rat.
International journal of pancreatology : official journal of the International Association of Pancreatology 1996;19(2):129-34.
1995: G Goldman; R Welbourn; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Neutrophil adhesion receptor CD18 mediates remote but not localized acid aspiration injury.
Surgery 1995;117(1):83-9.
1994: R Simpson; Herbert B Hechtman
Pulmonary injury following sepsis.
Progress in clinical and biological research 1994;388():265-75.
1993: R Simpson; R Alon; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion.
Annals of surgery 1993;218(4):444-53; discussion 453-4.
1993: R Simpson; R Alon; C R Valeri; D Shepro; Herbert B Hechtman
Integrin dependent neutrophil adhesion following gut ischemia and reperfusion.
Behring Institute Mitteilungen 1993;(92):210-7.
1993: G Goldman; R Welbourn; J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Leukocytes mediate acid aspiration-induced multiorgan edema.
Surgery 1993;114(1):13-20.
1993: M E Wiles; Herbert B Hechtman; N M Morel; D Shepro
Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells.
Journal of leukocyte biology 1993;53(5):490-7.
1993: G Goldman; R Welbourn; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Lavage with leukotriene B4 induces lung generation of tumor necrosis factor-alpha that in turn mediates neutrophil diapedesis.
Surgery 1993;113(3):297-303.
1993: J Hill; T Lindsay; C R Valeri; D Shepro; Herbert B Hechtman
A CD18 antibody prevents lung injury but not hypotension after intestinal ischemia-reperfusion.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(2):659-64.
1993: R Mineau-Hanschke; Wayne Patton; Herbert B Hechtman; D Shepro
Immunolocalization of cytokeratin 19 in bovine and human pulmonary microvascular endothelial cells in situ.
Comparative biochemistry and physiology. Comparative physiology 1993;104(2):313-9.
1992: T F Lindsay; J Hill; F Ortiz; A Rudolph; C R Valeri; Herbert B Hechtman; Francis D Moore
Blockade of complement activation prevents local and pulmonary albumin leak after lower torso ischemia-reperfusion.
Annals of surgery 1992;216(6):677-83.
1992: G Goldman; R Welbourn; R Rothlein; M Wiles; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Adherent neutrophils mediate permeability after atelectasis.
Annals of surgery 1992;216(3):372-8; discussion 378-80.
1992: J Hill; T F Lindsay; F Ortiz; C G Yeh; Herbert B Hechtman; Francis D Moore
Soluble complement receptor type 1 ameliorates the local and remote organ injury after intestinal ischemia-reperfusion in the rat.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1723-8.
1992: G Goldman; R Welbourn; J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents.
Surgery 1992;112(3):578-86.
1992: G Goldman; R Welbourn; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Reactive oxygen species and elastase mediate lung permeability after acid aspiration.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(2):571-5.
1992: J Hill; T Lindsay; J Rusche; C R Valeri; D Shepro; Herbert B Hechtman
A Mac-1 antibody reduces liver and lung injury but not neutrophil sequestration after intestinal ischemia-reperfusion.
Surgery 1992;112(2):166-72.
1992: R Welbourn; G Goldman; Lester Kobzik; I S Paterson; C R Valeri; D Shepro; Herbert B Hechtman
Role of neutrophil adherence receptors (CD 18) in lung permeability following lower torso ischemia.
Circulation research 1992;71(1):82-6.
1992: G Goldman; R Welbourn; J M Klausner; C R Valeri; D Shepro; Herbert B Hechtman
Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis.
Surgery 1992;111(3):287-93.
1992: G Goldman; R Welbourn; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury.
Surgery 1992;111(1):55-61.
1991: R Welbourn; G Goldman; Lester Kobzik; I Paterson; D Shepro; Herbert B Hechtman
Interleukin-2 induces early multisystem organ edema mediated by neutrophils.
Annals of surgery 1991;214(2):181-6.
1991: Wayne Patton; J S Alexander; A B Dodge; R J Patton; Herbert B Hechtman; D Shepro
Mercury-arc photolysis: a method for examining second messenger regulation of endothelial cell monolayer integrity.
Analytical biochemistry 1991;196(1):31-8.
1991: C R Welbourn; G Goldman; I S Paterson; C R Valeri; D Shepro; Herbert B Hechtman
Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil.
The British journal of surgery 1991;78(6):651-5.
1991: C R Welbourn; G Goldman; I S Paterson; C R Valeri; D Shepro; Herbert B Hechtman
Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia.
The American journal of physiology 1991;260(6 Pt 2):H1852-6.
1991: R Welbourn; G Goldman; M O'Riordain; T F Lindsay; I S Paterson; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Role for tumor necrosis factor as mediator of lung injury following lower torso ischemia.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(6):2645-9.
1991: M E Wiles; R Welbourn; G Goldman; Herbert B Hechtman; D Shepro
Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18.
Inflammation 1991;15(3):181-99.
1991: G Goldman; R Welbourn; C R Valeri; D Shepro; Herbert B Hechtman
Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation.
Microvascular research 1991;41(3):367-75.
1991: G Goldman; R Welbourn; J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Neutrophil accumulations due to pulmonary thromboxane synthesis mediate acid aspiration injury.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(4):1511-7.
1991: G Goldman; R Welbourn; S Alexander; J M Klausner; M Wiles; C R Valeri; D Shepro; Herbert B Hechtman
Modulation of pulmonary permeability in vivo with agents that affect the cytoskeleton.
Surgery 1991;109(4):533-8.
1991: G Goldman; R Welbourn; J M Klausner; C R Valeri; D Shepro; Herbert B Hechtman
Thromboxane mediates diapedesis after ischemia by activation of neutrophil adhesion receptors interacting with basally expressed intercellular adhesion molecule-1.
Circulation research 1991;68(4):1013-9.
1991: R Welbourn; G Goldman; Lester Kobzik; C R Valeri; Herbert B Hechtman; D Shepro
Attenuation of IL-2-induced multisystem organ edema by phalloidin and antamanide.
Journal of applied physiology (Bethesda, Md. : 1985) 1991;70(3):1364-8.
1991: J M Klausner; I S Paterson; G Goldman; Lester Kobzik; S Lelcuk; Y Skornick; Timothy J Eberlein; C R Valeri; D Shepro; Herbert B Hechtman
Interleukin-2-induced lung injury is mediated by oxygen free radicals.
Surgery 1991;109(2):169-75.
1991: G Goldman; R Welbourn; J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy.
The American journal of physiology 1991;260(2 Pt 2):H465-72.
1991: A B Dodge; Herbert B Hechtman; D Shepro
Microvascular endothelial-derived autacoids regulate pericyte contractility.
Cell motility and the cytoskeleton 1991;18(3):180-8.
1991: A B Dodge; Wayne Patton; M U Yoon; Herbert B Hechtman; D Shepro
Organ and species specific differences in cytoskeletal protein profiles of cultured microvascular endothelial cells.
Comparative biochemistry and physiology. B, Comparative biochemistry 1991;98(4):461-70.
1990: G Goldman; R Welbourn; J M Klausner; S Alexander; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Attenuation of acid aspiration edema with phalloidin.
The American journal of physiology 1990;259(6 Pt 1):L378-83.
1990: R Welbourn; G Goldman; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2.
Annals of surgery 1990;212(6):728-33.
1990: J M Klausner; G Goldman; Y Skornick; R Valeri; M Inbar; D Shepro; Herbert B Hechtman
Interleukin-2-induced lung permeability is mediated by leukotriene B4.
Cancer 1990;66(11):2357-64.
1990: G Goldman; R Welbourn; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Tumor necrosis factor-alpha mediates acid aspiration-induced systemic organ injury.
Annals of surgery 1990;212(4):513-9; discussion 519-20.
1990: N M Morel; P P Petruzzo; Herbert B Hechtman; D Shepro
Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction.
Inflammation 1990;14(5):571-83.
1990: R Welbourn; G Goldman; Lester Kobzik; I Paterson; C R Valeri; D Shepro; Herbert B Hechtman
Neutrophil adherence receptors (CD 18) in ischemia. Dissociation between quantitative cell surface expression and diapedesis mediated by leukotriene B4.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(6):1906-11.
1990: G Goldman; R Welbourn; I S Paterson; J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent.
Surgery 1990;107(4):428-33.
1990: Wayne Patton; M U Yoon; J S Alexander; N Chung-Welch; Herbert B Hechtman; D Shepro
Expression of simple epithelial cytokeratins in bovine pulmonary microvascular endothelial cells.
Journal of cellular physiology 1990;143(1):140-9.
1990: R Mineau-Hanschke; M E Wiles; N Morel; Herbert B Hechtman; D Shepro
Modulation of cultured pulmonary microvessel and arterial endothelial cell barrier structure and function by serotonin.
Microvascular research 1990;39(2):140-55.
1990: G Goldman; R Welbourn; J M Klausner; I S Paterson; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Ischemia activates neutrophils but inhibits their local and remote diapedesis.
Annals of surgery 1990;211(2):196-201.
1989: N M Morel; A B Dodge; Wayne Patton; I M Herman; Herbert B Hechtman; D Shepro
Pulmonary microvascular endothelial cell contractility on silicone rubber substrate.
Journal of cellular physiology 1989;141(3):653-9.
1989: I S Paterson; J M Klausner; G Goldman; Robert D Pugatch; H Feingold; P Allen; John A Mannick; C R Valeri; D Shepro; Herbert B Hechtman
Pulmonary edema after aneurysm surgery is modified by mannitol.
Annals of surgery 1989;210(6):796-801.
1989: N Chung-Welch; Wayne Patton; G P Yen-Patton; Herbert B Hechtman; D Shepro
Phenotypic comparison between mesothelial and microvascular endothelial cell lineages using conventional endothelial cell markers, cytoskeletal protein markers and in vitro assays of angiogenic potential.
Differentiation; research in biological diversity 1989;42(1):44-53.
1989: I S Paterson; J M Klausner; G Goldman; Lester Kobzik; R Welbourn; C R Valeri; D Shepro; Herbert B Hechtman
Thromboxane mediates the ischemia-induced neutrophil oxidative burst.
Surgery 1989;106(2):224-9.
1989: J M Klausner; I S Paterson; N M Morel; G Goldman; Alan Gray; R Valeri; Timothy J Eberlein; D Shepro; Herbert B Hechtman
Role of thromboxane in interleukin 2-induced lung injury in sheep.
Cancer research 1989;49(13):3542-9.
1989: I S Paterson; J M Klausner; G Goldman; R Welbourn; J S Alexander; D Shepro; Herbert B Hechtman
The endothelial cell cytoskeleton modulates extravascular polymorphonuclear leukocyte accumulations in vivo.
Microvascular research 1989;38(1):49-56.
1989: J M Klausner; I S Paterson; G Goldman; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Thromboxane A2 mediates increased pulmonary microvascular permeability following limb ischemia.
Circulation research 1989;64(6):1178-89.
1989: J M Klausner; I S Paterson; G Goldman; Lester Kobzik; C Rodzen; R Lawrence; C R Valeri; D Shepro; Herbert B Hechtman
Postischemic renal injury is mediated by neutrophils and leukotrienes.
The American journal of physiology 1989;256(5 Pt 2):F794-802.
1989: J M Klausner; I S Paterson; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Leukotrienes but not complement mediate limb ischemia-induced lung injury.
Annals of surgery 1989;209(4):462-70.
1989: J Doukas; Herbert B Hechtman; D Shepro
Vasoactive amines and eicosanoids interactively regulate both polymorphonuclear leukocyte diapedesis and albumin permeability in vitro.
Microvascular research 1989;37(2):125-37.
1989: J M Klausner; I S Paterson; John A Mannick; R Valeri; D Shepro; Herbert B Hechtman
Reperfusion pulmonary edema.
JAMA : the journal of the American Medical Association 1989;261(7):1030-5.
1989: I S Paterson; J M Klausner; Robert D Pugatch; P Allen; John A Mannick; D Shepro; Herbert B Hechtman
Noncardiogenic pulmonary edema after abdominal aortic aneurysm surgery.
Annals of surgery 1989;209(2):231-6.
1989: J M Klausner; I S Paterson; Lester Kobzik; C Rodzen; C R Valeri; D Shepro; Herbert B Hechtman
Vasodilating prostaglandins attenuate ischemic renal injury only if thromboxane is inhibited.
Annals of surgery 1989;209(2):219-24.
1989: J M Klausner; I S Paterson; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Oxygen free radicals mediate ischemia-induced lung injury.
Surgery 1989;105(2 Pt 1):192-9.
1989: J M Klausner; N Morel; I S Paterson; Lester Kobzik; C R Valeri; Timothy J Eberlein; D Shepro; Herbert B Hechtman
The rapid induction by interleukin-2 of pulmonary microvascular permeability.
Annals of surgery 1989;209(1):119-28.
1989: R Mineau-Hanschke; Herbert B Hechtman; D Shepro
Endothelial cell junctional integrity modulation by serotonin: an ultrastructural analysis.
Tissue & cell 1989;21(2):161-70.
1988: J M Klausner; H Anner; I S Paterson; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Lower torso ischemia-induced lung injury is leukocyte dependent.
Annals of surgery 1988;208(6):761-7.
1988: J M Klausner; I S Paterson; C R Valeri; D Shepro; Herbert B Hechtman
Limb ischemia-induced increase in permeability is mediated by leukocytes and leukotrienes.
Annals of surgery 1988;208(6):755-60.
1988: J M Klausner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Selective lung leukosequestration after complement activation.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(1):80-8.
1988: W V Huval; S Lelcuk; H Feingold; C R Valeri; D Shepro; Herbert B Hechtman
Effects of nitroprusside and ketanserin upon pulmonary edema after acid injury.
Surgery, gynecology & obstetrics 1988;166(6):527-34.
1988: J S Alexander; Herbert B Hechtman; D Shepro
Phalloidin enhances endothelial barrier function and reduces inflammatory permeability in vitro.
Microvascular research 1988;35(3):308-15.
1988: H Anner; R P Kaufman; C R Valeri; D Shepro; Herbert B Hechtman
Reperfusion of ischemic lower limbs increases pulmonary microvascular permeability.
The Journal of trauma 1988;28(5):607-10.
1988: N Chung-Welch; D Shepro; B Dunham; Herbert B Hechtman
Prostacyclin and prostaglandin E2 secretions by bovine pulmonary microvessel endothelial cells are altered by changes in culture conditions.
Journal of cellular physiology 1988;135(2):224-34.
1988: R P Kaufman; J M Klausner; H Anner; H Feingold; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Inhibition of thromboxane (Tx) synthesis by free radical scavengers.
The Journal of trauma 1988;28(4):458-64.
1988: J C Austin; L D Berrizbeitia; Frederick J Schoen; R P Kauffman; Herbert B Hechtman; Lawrence H Cohn
Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion.
American heart journal 1988;115(3):505-9.
1987: H Anner; R P Kaufman; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Pulmonary hypertension and leukosequestration after lower torso ischemia.
Annals of surgery 1987;206(5):642-8.
1987: R P Kaufman; H Anner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
Surgery, gynecology & obstetrics 1987;165(5):404-9.
1987: H Anner; R P Kaufman; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Pulmonary leukosequestration induced by hind limb ischemia.
Annals of surgery 1987;206(2):162-7.
1987: R P Kaufman; H Anner; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Vasodilator prostaglandins (PG) prevent renal damage after ischemia.
Annals of surgery 1987;205(2):195-8.
1986: F Alexander; J Manny; S Lelcuk; D Shepro; Herbert B Hechtman
Cyclo-oxygenase products mediate hypoxic pulmonary hypertension.
Journal of pediatric surgery 1986;21(12):1101-7.
1986: J Manny; N Manny; S Lelcuk; F Alexander; H Feingold; Lester Kobzik; C R Valeri; D Shepro; Herbert B Hechtman
Pulmonary and systemic consequences of localized acid aspiration.
Surgery, gynecology & obstetrics 1986;162(3):259-67.
1986: S B Palder; W Huval; S Lelcuk; F Alexander; D Shepro; J A Mannick; Herbert B Hechtman
Reduction of polymorphonuclear leukocyte accumulations by inhibition of cyclooxygenase and thromboxane syntase in the rabbit.
Surgery 1986;99(1):72-81.
1984: V J DiSesa; W Huval; S Lelcuk; R Jonas; R Maddi; S Lee-Son; R J Shemin; J J Collins; Herbert B Hechtman; L H Cohn
Disadvantages of prostacyclin infusion during cardiopulmonary bypass: a double-blind study of 50 patients having coronary revascularization.
The Annals of thoracic surgery 1984;38(5):514-9.
1984: W V Huval; S Lelcuk; D Shepro; Herbert B Hechtman
Role of serotonin in patients with acute respiratory failure.
Annals of surgery 1984;200(2):166-72.
1984: F Alexander; M Mathieson; K H Teoh; W V Huval; S Lelcuk; C R Valeri; D Shepro; Herbert B Hechtman
Arachidonic acid metabolites mediate early burn edema.
The Journal of trauma 1984;24(8):709-12.
1984: S Lelcuk; W V Huval; C R Valeri; D Shepro; Herbert B Hechtman
Inhibition of ischemia-induced thromboxane synthesis in man.
The Journal of trauma 1984;24(5):393-6.
1984: W V Huval; S Lelcuk; P D Allen; J A Mannick; D Shepro; Herbert B Hechtman
Determinants of cardiovascular stability during abdominal aortic aneurysmectomy (AAA).
Annals of surgery 1984;199(2):216-22.
1983: M A Mathieson; B M Dunham; W V Huval; S Lelcuk; L I Stemp; C R Valeri; D Shepro; Herbert B Hechtman
Ischemia of the limb stimulates thromboxane production and myocardial depression.
Surgery, gynecology & obstetrics 1983;157(6):500-4.
1983: W V Huval; B M Dunham; S Lelcuk; C R Valeri; D Shepro; Herbert B Hechtman
Thromboxane mediation of cardiovascular dysfunction following aspiration.
Surgery 1983;94(2):259-66.
1983: Herbert B Hechtman; W V Huval; M A Mathieson; L I Stemp; C R Valeri; D Shepro
Prostaglandin and thromboxane mediation of cardiopulmonary failure.
The Surgical clinics of North America 1983;63(2):263-83.
1983: W V Huval; M A Mathieson; L I Stemp; B M Dunham; A G Jones; D Shepro; Herbert B Hechtman
Therapeutic benefits of 5-hydroxytryptamine inhibition following pulmonary embolism.
Annals of surgery 1983;197(2):220-5.