Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

David Hedley

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Procedures

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Physiology

Phenomena

Phosphorylation

Concepts & Ideas

Ploidies

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Ito Emma; Yip Kenneth W; Katz David; Fonseca Sonali B; Hedley David W; Chow Sue; Xu G Wei; Wood Tabitha E; Bastianutto Carlo; Schimmer Aaron D; Kelley Shana O; Liu Fei-Fei
Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer.
Schimmer Aaron D; Estey Elihu H; Borthakur Gautam; Carter Bing Z; Schiller Gary J; Tallman Martin S; Altman Jessica K; Karp Judith E; Kassis Jeannine; Hedley David W; Brandwein Joseph; Xu Wei; Mak Duncan H; LaCasse Eric; Jacob Christine; Morris Stephen J; Jolivet Jacques; Andreeff Michael
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Schwock Joerg; Dhani Neesha; Cao Mary Ping-Jiang; Zheng Jinzi; Clarkson Richard; Radulovich Nikolina; Navab Roya; Horn Lars-Christian; Hedley David W
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of David Hedley (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Ito Emma; Yip Kenneth W; Katz David; Fonseca Sonali B; Hedley David W; Chow Sue; Xu G Wei; Wood Tabitha E; Bastianutto Carlo; Schimmer Aaron D; Kelley Shana O; Liu Fei-Fei
Potential use of cetrimonium bromide as an apoptosis-promoting anticancer agent for head and neck cancer.
Molecular pharmacology 2009;76(5):969-83.
2009: Schimmer Aaron D; Estey Elihu H; Borthakur Gautam; Carter Bing Z; Schiller Gary J; Tallman Martin S; Altman Jessica K; Karp Judith E; Kassis Jeannine; Hedley David W; Brandwein Joseph; Xu Wei; Mak Duncan H; LaCasse Eric; Jacob Christine; Morris Stephen J; Jolivet Jacques; Andreeff Michael
Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(28):4741-6.
2009: Schwock Joerg; Dhani Neesha; Cao Mary Ping-Jiang; Zheng Jinzi; Clarkson Richard; Radulovich Nikolina; Navab Roya; Horn Lars-Christian; Hedley David W
Targeting focal adhesion kinase with dominant-negative FRNK or Hsp90 inhibitor 17-DMAG suppresses tumor growth and metastasis of SiHa cervical xenografts.
Cancer research 2009;69(11):4750-9.
2009: Cao P; Maira S-M; García-Echeverría C; Hedley D W
Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts.
British journal of cancer 2009;100(8):1267-76.
2009: Hill Richard P; Marie-Egyptienne Delphine T; Hedley David W
Cancer stem cells, hypoxia and metastasis.
Seminars in radiation oncology 2009;19(2):106-11.
2009: Pintilie Melania; Iakovlev Vladimir; Fyles Anthony; Hedley David; Milosevic Michael; Hill Richard P
Heterogeneity and power in clinical biomarker studies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(9):1517-21.
2008: Chow Sue; Hedley David; Shankey T Vincent
Whole blood processing for measurement of signaling proteins by flow cytometry.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2008;Chapter 9():Unit 9.27.
2008: Chang Q; Jorgensen C; Pawson T; Hedley D W
Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.
British journal of cancer 2008;99(7):1074-82.
2008: Mao Xinliang; Liang Sheng-ben; Hurren Rose; Gronda Marcela; Chow Sue; Xu G Wei; Wang Xiaoming; Zavareh Reza Beheshti; Jamal Nazir; Messner Hans; Hedley David W; Datti Alessandro; Wrana Jeff L; Zhu Yuanxiao; Shi Chang-xin; Lee Kyle; Tiedemann Rodger; Trudel Suzanne; Stewart A Keith; Schimmer Aaron D
Cyproheptadine displays preclinical activity in myeloma and leukemia.
Blood 2008;112(3):760-9.
2008: Schwock Jörg; Pham Nhu-An; Cao Mary P; Hedley David W
Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
Cancer chemotherapy and pharmacology 2008;61(4):669-81.
2008: Hedley David W; Chow Sue; Goolsby Charles; Shankey T Vincent
Pharmacodynamic monitoring of molecular-targeted agents in the peripheral blood of leukemia patients using flow cytometry.
Toxicologic pathology 2008;36(1):133-9.
2008: Pham Nhu-An; Schwock Joerg; Iakovlev Vladimir; Pond Greg; Hedley David W; Tsao Ming-Sound
Immunohistochemical analysis of changes in signaling pathway activation downstream of growth factor receptors in pancreatic duct cell carcinogenesis.
BMC cancer 2008;8():43.
2007: Pham Nhu-An; Tsao Ming-Sound; Cao Pinjiang; Hedley David William
Dissociation of gemcitabine sensitivity and protein kinase B signaling in pancreatic ductal adenocarcinoma models.
Pancreas 2007;35(3):e16-26.
2007: Schwock Jörg; Ho James C; Luther Ed; Hedley David W; Geddie William R
Measurement of signaling pathway activities in solid tumor fine-needle biopsies by slide-based cytometry.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007;16(3):130-40.
2007: Agulnik Mark; da Cunha Santos Gilda; Hedley David; Nicklee Trudey; Dos Reis Patricia Pintor; Ho James; Pond Gregory R; Chen Heidi; Chen Shuo; Shyr Yu; Winquist Eric; Soulieres Denis; Chen Eric X; Squire Jeremy A; Marrano Paula; Kamel-Reid Suzanne; Dancey Janet; Siu Lillian L; Tsao Ming S
Predictive and pharmacodynamic biomarker studies in tumor and skin tissue samples of patients with recurrent or metastatic squamous cell carcinoma of the head and neck treated with erlotinib.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(16):2184-90.
2007: Brade Anthony; Brierley James; Oza Amit; Gallinger Steven; Cummings Bernard; Maclean Martha; Pond Gregory R; Hedley David; Wong Shun; Townsley Carol; Brezden-Masley Christine; Moore Malcolm
Concurrent gemcitabine and radiotherapy with and without neoadjuvant gemcitabine for locally advanced unresectable or resected pancreatic cancer: a phase I-II study.
International journal of radiation oncology, biology, physics 2007;67(4):1027-36.
2007: Birle Diana C; Hedley David W
Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.
Cancer research 2007;67(4):1735-43.
2007: Pham Nhu-An; Morrison Andrew; Schwock Joerg; Aviel-Ronen Sarit; Iakovlev Vladimir; Tsao Ming-Sound; Ho James; Hedley David W
Quantitative image analysis of immunohistochemical stains using a CMYK color model.
Diagnostic pathology 2007;2():8.
2006: Duran I; Kortmansky J; Singh D; Hirte H; Kocha W; Goss G; Le L; Oza A; Nicklee T; Ho J; Birle D; Pond G R; Arboine D; Dancey J; Aviel-Ronen S; Tsao M-S; Hedley D; Siu L L
A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas.
British journal of cancer 2006;95(9):1148-54.
2006: Birle Diana C; Hedley David W
Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts.
Molecular cancer therapeutics 2006;5(10):2494-502.
2006: Yip Kenneth W; Mao Xinliang; Au P Y Billie; Hedley David W; Chow Sue; Dalili Shadi; Mocanu Joseph D; Bastianutto Carlo; Schimmer Aaron; Liu Fei-Fei
Benzethonium chloride: a novel anticancer agent identified by using a cell-based small-molecule screen.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(18):5557-69.
2006: Yip Kenneth W; Ito Emma; Mao Xinliang; Au P Y Billie; Hedley David W; Mocanu Joseph D; Bastianutto Carlo; Schimmer Aaron; Liu Fei-Fei
Potential use of alexidine dihydrochloride as an apoptosis-promoting anticancer agent.
Molecular cancer therapeutics 2006;5(9):2234-40.
2006: Chow Sue; Minden Mark D; Hedley David W
Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients.
Experimental hematology 2006;34(9):1183-91.
2006: Gurfinkel Debbie M; Chow Sue; Hurren Rose; Gronda Marcela; Henderson Clare; Berube Christina; Hedley David W; Schimmer Aaron D
Disruption of the endoplasmic reticulum and increases in cytoplasmic calcium are early events in cell death induced by the natural triterpenoid Asiatic acid.
Apoptosis : an international journal on programmed cell death 2006;11(9):1463-71.
2006: Tong Frances K; Chow Sue; Hedley David
Pharmacodynamic monitoring of BAY 43-9006 (Sorafenib) in phase I clinical trials involving solid tumor and AML/MDS patients, using flow cytometry to monitor activation of the ERK pathway in peripheral blood cells.
Cytometry. Part B, Clinical cytometry 2006;70(3):107-14.
2006: Townsley C A; Major P; Siu L L; Dancey J; Chen E; Pond G R; Nicklee T; Ho J; Hedley D; Tsao M; Moore M J; Oza A M
Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer.
British journal of cancer 2006;94(8):1136-43.
2005: Primeau Andrew J; Rendon Augusto; Hedley David; Lilge Lothar; Tannock Ian F
The distribution of the anticancer drug Doxorubicin in relation to blood vessels in solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(24 Pt 1):8782-8.
2005: Schwock Jörg; Geddie William R; Hedley David W
Analysis of hypoxia-inducible factor-1alpha accumulation and cell cycle in geldanamycin-treated human cervical carcinoma cells by laser scanning cytometry.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2005;68(2):59-70.
2005: Bindra Ranjit S; Schaffer Paul J; Meng Alice; Woo Jennifer; Måseide Kårstein; Roth Matt E; Lizardi Paul; Hedley David W; Bristow Robert G; Glazer Peter M
Alterations in DNA repair gene expression under hypoxia: elucidating the mechanisms of hypoxia-induced genetic instability.
Annals of the New York Academy of Sciences 2005;1059():184-95.
2005: Chow Sue; Hedley David; Grom Patricia; Magari Robert; Jacobberger James W; Shankey T Vincent
Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2005;67(1):4-17.
2005: Mackay Helen; Hedley David; Major Pierre; Townsley Carol; Mackenzie Mary; Vincent Mark; Degendorfer Pam; Tsao Ming-Sound; Nicklee Trudey; Birle Diana; Wright John; Siu Lillian; Moore Malcolm; Oza Amit
A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5526-33.
2005: Ringash J; Khaksart S J; Oza A; Couture J; Japp B; Moore M; Siu L L; Hedley D; Swallow C; Wong S; Cummings B; Kim J; Wong R; Brierley J
Post-operative radiochemotherapy for gastric cancer: adoption and adaptation.
Clinical oncology (Royal College of Radiologists (Great Britain)) 2005;17(2):91-5.
2005: Sridhar Srikala S; Hedley David; Siu Lillian L
Raf kinase as a target for anticancer therapeutics.
Molecular cancer therapeutics 2005;4(4):677-85.
2005: Knox Jennifer J; Hedley David; Oza Amit; Feld Ron; Siu Lillian L; Chen Eric; Nematollahi Mahsan; Pond Gregory R; Zhang Jessica; Moore Malcolm J
Combining gemcitabine and capecitabine in patients with advanced biliary cancer: a phase II trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(10):2332-8.
2005: Yau Cindy Y F; Wheeler Jeffery J; Sutton Kymberley L; Hedley David W
Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth, and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts.
Cancer research 2005;65(4):1497-504.
2005: Hedley David W; Nicklee Trudey; Moreno-Merlo Fernando; Pintilie Melania; Fyles Anthony; Milosevic Michael; Hill Richard P
Relations between non-protein sulfydryl levels in the nucleus and cytoplasm, tumor oxygenation, and clinical outcome of patients with uterine cervical carcinoma.
International journal of radiation oncology, biology, physics 2005;61(1):137-44.
2004: Michael Michael; Brittain MaryAnne; Nagai Jane; Feld Ronald; Hedley David; Oza Amit; Siu Lillian; Moore Malcolm J
Phase II study of activated charcoal to prevent irinotecan-induced diarrhea.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(21):4410-7.
2004: Pham Nhu-An; Jacobberger James W; Schimmer Aaron D; Cao Pinjiang; Gronda Marcella; Hedley David W
The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.
Molecular cancer therapeutics 2004;3(10):1239-48.
2004: Bindra Ranjit S; Schaffer Paul J; Meng Alice; Woo Jennifer; Måseide Kårstein; Roth Matt E; Lizardi Paul; Hedley David W; Bristow Robert G; Glazer Peter M
Down-regulation of Rad51 and decreased homologous recombination in hypoxic cancer cells.
Molecular and cellular biology 2004;24(19):8504-18.
2004: Lau J P; Weatherdon K L; Skalski V; Hedley D W
Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides.
British journal of cancer 2004;91(6):1166-73.
2004: Milosevic Michael; Fyles Anthony; Hedley David; Hill Richard
The human tumor microenvironment: invasive (needle) measurement of oxygen and interstitial fluid pressure.
Seminars in radiation oncology 2004;14(3):249-58.
2004: Måseide Kårstein; Kandel Rita A; Bell Robert S; Catton Charles N; O'Sullivan Brian; Wunder Jay S; Pintilie Melania; Hedley David; Hill Richard P
Carbonic anhydrase IX as a marker for poor prognosis in soft tissue sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(13):4464-71.
2004: Knox J J; Hedley D; Oza A; Siu L L; Pond G R; Moore M J
Gemcitabine concurrent with continuous infusional 5-fluorouracil in advanced biliary cancers: a review of the Princess Margaret Hospital experience.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2004;15(5):770-4.
2004: Hedley David; Pintilie Melania; Woo Jennifer; Nicklee Trudey; Morrison Andrew; Birle Diana; Fyles Anthony; Milosevic Michael; Hill Richard
Up-regulation of the redox mediators thioredoxin and apurinic/apyrimidinic excision (APE)/Ref-1 in hypoxic microregions of invasive cervical carcinomas, mapped using multispectral, wide-field fluorescence image analysis.
The American journal of pathology 2004;164(2):557-65.
2003: Hedley David; Pintilie Melania; Woo Jennifer; Morrison Andrew; Birle Diana; Fyles Anthony; Milosevic Michael; Hill Richard
Carbonic anhydrase IX expression, hypoxia, and prognosis in patients with uterine cervical carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(15):5666-74.
2003: Yee Karen W L; Moore Susan J; Midmer Michael; Zanke Brent W; Tong Frances; Hedley David; Minden Mark D
NKIAMRE, a novel conserved CDC2-related kinase with features of both mitogen-activated protein kinases and cyclin-dependent kinases.
Biochemical and biophysical research communications 2003;308(4):784-92.
2003: Weir Iona E; Pham Nhu-An; Hedley David W
Oxidative stress is generated via the mitochondrial respiratory chain during plant cell apoptosis.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;54(2):109-17.
2003: Jacobberger James W; Sramkoski R Michael; Frisa Phyllis S; Ye Peggy Peng; Gottlieb Megan A; Hedley David W; Shankey T Vincent; Smith Bradley L; Paniagua Mary; Goolsby Charles L
Immunoreactivity of Stat5 phosphorylated on tyrosine as a cell-based measure of Bcr/Abl kinase activity.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;54(2):75-88.
2003: Nottage Michelle; McLachlan Sue-Anne; Brittain Mary-Anne; Oza Amit; Hedley David; Feld Ronald; Siu Lillian L; Pond Gregory; Moore Malcolm J
Sucralfate mouthwash for prevention and treatment of 5-fluorouracil-induced mucositis: a randomized, placebo-controlled trial.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2003;11(1):41-7.
2003: Davis A J; Chapman W; Hedley D W; Oza A M; Tannock I F
Assessment of tumor cell repopulation after chemotherapy for advanced ovarian cancer: pilot study.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003;51(1):1-6.
2002: Lin Yunping; Brown Lauren; Hedley David W; Barber Dwayne L; Benchimol Samuel
The death-promoting activity of p53 can be inhibited by distinct signaling pathways.
Blood 2002;100(12):3990-4000.
2002: Ng Sylvia S W; Tsao Ming-Sound; Nicklee Trudey; Hedley David W
Effects of the epidermal growth factor receptor inhibitor OSI-774, Tarceva, on downstream signaling pathways and apoptosis in human pancreatic adenocarcinoma.
Molecular cancer therapeutics 2002;1(10):777-83.
2002: Haugland Hans Kristian; Vukovic Vojislav; Pintilie Melania; Fyles Anthony W; Milosevic Michael; Hill Richard P; Hedley David W
Expression of hypoxia-inducible factor-1alpha in cervical carcinomas: correlation with tumor oxygenation.
International journal of radiation oncology, biology, physics 2002;53(4):854-61.
2002: Vukovic Vojislav; Nicklee Trudey; Hedley David W
Multiparameter fluorescence mapping of nonprotein sulfhydryl status in relation to blood vessels and hypoxia in cervical carcinoma xenografts.
International journal of radiation oncology, biology, physics 2002;52(3):837-43.
2002: Fyles A; Milosevic M; Hedley D; Pintilie M; Levin W; Manchul L; Hill R P
Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(3):680-7.
2001: Schimmer A D; Hedley D W; Penn L Z; Minden M D
Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational view.
Blood 2001;98(13):3541-53.
2001: Vukovic V; Haugland H K; Nicklee T; Morrison A J; Hedley D W
Hypoxia-inducible factor-1alpha is an intrinsic marker for hypoxia in cervical cancer xenografts.
Cancer research 2001;61(20):7394-8.
2001: Ng S S; Tsao M S; Nicklee T; Hedley D W
Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3269-75.
2001: Milosevic M; Fyles A; Hedley D; Pintilie M; Levin W; Manchul L; Hill R
Interstitial fluid pressure predicts survival in patients with cervix cancer independent of clinical prognostic factors and tumor oxygen measurements.
Cancer research 2001;61(17):6400-5.
2001: Schimmer A D; Hedley D W; Pham N A; Chow S; Minden M D
BAD induces apoptosis in cells over-expressing Bcl-2 or Bcl-xL without loss of mitochondrial membrane potential.
Leukemia & lymphoma 2001;42(3):429-43.
2001: Constantinou P; Vukovic V; Haugland H K; Nicklee T; Hedley D W; Wilson B C
Imaging of whole tumor cut sections using a novel scanning beam confocal fluorescence MACROscope.
Journal of biomedical optics 2001;6(3):326-31.
2001: Schimmer A D; Hedley D W; Chow S; Pham N A; Chakrabartty A; Bouchard D; Mak T W; Trus M R; Minden M D
The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2.
Cell death and differentiation 2001;8(7):725-33.
2001: Vukovic V; Nicklee T; Hedley D W
Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2001;60(1):69-73.
2001: Chow S; Hedley D
Flow cytometric measurement of intracellular pH.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2001;Chapter 9():Unit 9.3.
2001: Chow S; Patel H; Hedley D W
Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.
Cytometry 2001;46(2):72-8.
2001: Pham N A; Hedley D W
Respiratory chain-generated oxidative stress following treatment of leukemic blasts with DNA-damaging agents.
Experimental cell research 2001;264(2):345-52.
2001: Muzzammil T; Moore M J; Hedley D; Ballinger J R
Comparison of (99m)Tc-sestamibi and doxorubicin to monitor inhibition of P-glycoprotein function.
British journal of cancer 2001;84(3):367-73.
2000: Dimitroulakos J; Thai S; Wasfy G H; Hedley D W; Minden M D; Penn L Z
Lovastatin induces a pronounced differentiation response in acute myeloid leukemias.
Leukemia & lymphoma 2000;40(1-2):167-78.
2000: Pham N A; Robinson B H; Hedley D W
Simultaneous detection of mitochondrial respiratory chain activity and reactive oxygen in digitonin-permeabilized cells using flow cytometry.
Cytometry 2000;41(4):245-51.
2000: Rauchwerger D R; Firby P S; Hedley D W; Moore M J
Equilibrative-sensitive nucleoside transporter and its role in gemcitabine sensitivity.
Cancer research 2000;60(21):6075-9.
2000: Ng SSW; Tsao M S; Chow S; Hedley D W
Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells.
Cancer research 2000;60(19):5451-5.
2000: Vukovic V; Pheng S R; Stewart A; Vik C H; Hedley D W
Protection from radiation-induced DNA single-strand breaks by induction of nuclear metallothionein.
International journal of radiation biology 2000;76(6):757-62.
2000: Vukovic V; Nicklee T; Hedley D W
Microregional heterogeneity of non-protein thiols in cervical carcinomas assessed by combined use of HPLC and fluorescence image analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(5):1826-32.
1999: Moreno-Merlo F; Nicklee T; Hedley D W
Association between tissue hypoxia and elevated non-protein sulphydryl concentrations in human cervical carcinoma xenografts.
British journal of cancer 1999;81(6):989-93.
1999: Kavanagh M C; Tsang V; Chow S; Koch C; Hedley D; Minkin S; Hill R P
A comparison in individual murine tumors of techniques for measuring oxygen levels.
International journal of radiation oncology, biology, physics 1999;44(5):1137-46.
1999: Lee S T; Hoeflich K P; Wasfy G W; Woodgett J R; Leber B; Andrews D W; Hedley D W; Penn L Z
Bcl-2 targeted to the endoplasmic reticulum can inhibit apoptosis induced by Myc but not etoposide in Rat-1 fibroblasts.
Oncogene 1999;18(23):3520-8.
1999: Crump M; Lipton J; Hedley D; Sutton D; Shepherd F; Minden M; Stewart K; Beare S; Eisenhauer E
Phase I trial of sequential topotecan followed by etoposide in adults with myeloid leukemia: a National Cancer Institute of Canada Clinical Trials Group Study.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(3):343-7.
1999: Dimitroulakos J; Nohynek D; Backway K L; Hedley D W; Yeger H; Freedman M H; Minden M D; Penn L Z
Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach.
Blood 1999;93(4):1308-18.
1998: Sheng-Tanner X; Bump E A; Hedley D W
An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry.
Radiation research 1998;150(6):636-47.
1998: De Jaeger K; Merlo F M; Kavanagh M C; Fyles A W; Hedley D; Hill R P
Heterogeneity of tumor oxygenation: relationship to tumor necrosis, tumor size, and metastasis.
International journal of radiation oncology, biology, physics 1998;42(4):717-21.
1998: Hedley D W; McCulloch E A; Minden M D; Chow S; Curtis J
Antileukemic action of buthionine sulfoximine: evidence for an intrinsic death mechanism based on oxidative stress.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1998;12(10):1545-52.
1998: Moore M J; Feld R; Hedley D; Oza A; Siu L L
A phase II study of temozolomide in advanced untreated pancreatic cancer.
Investigational new drugs 1998;16(1):77-9.
1997: Backway K L; McCulloch E A; Chow S; Hedley D W
Relationships between the mitochondrial permeability transition and oxidative stress during ara-C toxicity.
Cancer research 1997;57(12):2446-51.
1997: Hedley D W; Xie S X; Minden M D; Choi C H; Chen H; Ling V
A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11(1):48-53.
1996: Nicklee T; Crump M; Hedley D W
Effects of topoisomerase I inhibition on the expression of topoisomerase II alpha measured with fluorescence image cytometry.
Cytometry 1996;25(3):205-10.
1996: Chow S; Hedley D; Tannock I
Flow cytometric calibration of intracellular pH measurements in viable cells using mixtures of weak acids and bases.
Cytometry 1996;24(4):360-7.
1995: Xie X Y; Robb D; Chow S; Hedley D W
Discordant P-glycoprotein antigen expression and transport function in acute myeloid leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(11):1882-7.
1995: Chow S; Hedley D
Flow cytometric determination of glutathione in clinical samples.
Cytometry 1995;21(1):68-71.
1995: Thomas M; Nicklee T; Hedley D W
Differential effects of depleting agents on cytoplasmic and nuclear non-protein sulphydryls: a fluorescence image cytometry study.
British journal of cancer 1995;72(1):45-50.
1995: Brown G A; McPherson J P; Gu L; Hedley D W; Toso R; Deuchars K L; Freedman M H; Goldenberg G J
Relationship of DNA topoisomerase II alpha and beta expression to cytotoxicity of antineoplastic agents in human acute lymphoblastic leukemia cell lines.
Cancer research 1995;55(1):78-82.
1994: Brezden C B; Hedley D W; Rauth A M
Constitutive expression of P-glycoprotein as a determinant of loading with fluorescent calcium probes.
Cytometry 1994;17(4):343-8.
1994: Hedley D W; Chow S
Evaluation of methods for measuring cellular glutathione content using flow cytometry.
Cytometry 1994;15(4):349-58.
1994: Hedley D W
DNA analysis from paraffin-embedded blocks.
Methods in cell biology 1994;41():231-40.
1994: Hedley D; Chow S
Glutathione and cellular resistance to anti-cancer drugs.
Methods in cell biology 1994;42 Pt B():31-44.
1994: Boyer M J; Hedley D W
Measurement of intracellular pH.
Methods in cell biology 1994;41():135-48.
1993: Boyer M J; Barnard M; Hedley D W; Tannock I F
Regulation of intracellular pH in subpopulations of cells derived from spheroids and solid tumours.
British journal of cancer 1993;68(5):890-7.
1993: Hedley D W
Flow cytometric assays of anticancer drug resistance.
Annals of the New York Academy of Sciences 1993;677():341-53.
1992: Deffie A M; McPherson J P; Gupta R S; Hedley D W; Goldenberg G J
Multifactorial resistance to antineoplastic agents in drug-resistant P388 murine leukemia, Chinese hamster ovary, and human HeLa cells, with emphasis on the role of DNA topoisomerase II.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1992;70(5):354-64.
1992: Hedley D; Chow S
Flow cytometric measurement of lipid peroxidation in vital cells using parinaric acid.
Cytometry 1992;13(7):686-92.
1990: Hedley D W; Hallahan A R; Tripp E H
Flow cytometric measurement of glutathione content of human cancer biopsies.
British journal of cancer 1990;61(1):65-8.
1989: Hedley D W
Flow cytometry using paraffin-embedded tissue: five years on.
Cytometry 1989;10(3):229-41.
1989: Hedley D W; Jorgensen H B
Flow cytometric measurement of intracellular pH in B16 tumors: intercell variance and effects of pretreatment with glucose.
Experimental cell research 1989;180(1):106-16.
1988: Hedley D W; Tripp E H; Slowiaczek P; Mann G J
Effect of gallium on DNA synthesis by human T-cell lymphoblasts.
Cancer research 1988;48(11):3014-8.
1988: Friedlander M L; Hedley D W; Swanson C; Russell P
Prediction of long-term survival by flow cytometric analysis of cellular DNA content in patients with advanced ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(2):282-90.
1987: Young G A; Hedley D W; Rugg C A; Iland H J
The prognostic significance of proliferative activity in poor histology non-Hodgkin's lymphoma: a flow cytometry study using archival material.
European journal of cancer & clinical oncology 1987;23(10):1497-504.
1987: Musgrove E; Seaman M; Hedley D
Relationship between cytoplasmic pH and proliferation during exponential growth and cellular quiescence.
Experimental cell research 1987;172(1):65-75.
1987: Hedley D W; Rugg C A; Gelber R D
Association of DNA index and S-phase fraction with prognosis of nodes positive early breast cancer.
Cancer research 1987;47(17):4729-35.
1987: deFazio A; Leary J A; Hedley D W; Tattersall M H
Immunohistochemical detection of proliferating cells in vivo.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1987;35(5):571-7.
1987: Kirsten F; Chi C H; Leary J A; Ng A B; Hedley D W; Tattersall M H
Metastatic adeno or undifferentiated carcinoma from an unknown primary site--natural history and guidelines for identification of treatable subsets.
The Quarterly journal of medicine 1987;62(238):143-61.
1985: Hedley D W; Friedlander M L; Taylor I W
Application of DNA flow cytometry to paraffin-embedded archival material for the study of aneuploidy and its clinical significance.
Cytometry 1985;6(4):327-33.
1985: Stuart-Harris R; Hedley D W; Taylor I W; Levene A L; Smith I E
Tumour ploidy, response and survival in patients receiving endocrine therapy for advanced breast cancer.
British journal of cancer 1985;51(4):573-6.
1985: Hedley D W; Leary J A; Kirsten F
Metastatic adenocarcinoma of unknown primary site: abnormalities of cellular DNA content and survival.
European journal of cancer & clinical oncology 1985;21(2):185-9.
1984: Hedley D W; Rugg C A; Ng A B; Taylor I W
Influence of cellular DNA content on disease-free survival of Stage II breast cancer patients.
Cancer research 1984;44(11):5395-8.
1984: Hedley D W; Friedlander M L; Taylor I W; Rugg C A; Musgrove E A
DNA flow cytometry of paraffin-embedded tissue.
Cytometry 1984;5(6):660.
1984: Friedlander M L; Hedley D W; Taylor I W
Clinical and biological significance of aneuploidy in human tumours.
Journal of clinical pathology 1984;37(9):961-74.
1984: Friedlander M L; Russell P; Taylor I W; Hedley D W; Tattersall M H
Flow cytometric analysis of cellular DNA content as an adjunct to the diagnosis of ovarian tumours of borderline malignancy.
Pathology 1984;16(3):301-6.
1984: Hedley D W; Philips J; Rugg C A; Taylor I W
Measurement of cellular DNA content as an adjunct to diagnostic cytology in malignant effusions.
European journal of cancer & clinical oncology 1984;20(6):749-52.
1984: Friedlander M L; Hedley D W; Taylor I W; Russell P; Coates A S; Tattersall M H
Influence of cellular DNA content on survival in advanced ovarian cancer.
Cancer research 1984;44(1):397-400.
1983: Hedley D W; Friedlander M L; Taylor I W; Rugg C A; Musgrove E A
Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1983;31(11):1333-5.
1983: Taylor I W; Musgrove E A; Friedlander M L; Foo M S; Hedley D W
The influence of age on the DNA ploidy levels of breast tumours.
European journal of cancer & clinical oncology 1983;19(5):623-8.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

David Hedley

Research Profile (preview)

Procedures

Anatomy

Living Beings

Chemicals & Drugs

Disorders

Physiology

Phenomena

Concepts & Ideas

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of David Hedley (preview)

All Publications