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Hargita Hegyesi

Research Profile

Chemicals & Drugs

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Andrea Balogh; Anett Benedek; Enikő Noémi Bogdándi; Hargita Hegyesi; Eszter Persa; Géza Sáfrány; Katalin Lumniczky
The effect of ionizing radiation on the homeostasis and functional integrity of murine splenic regulatory T cells.
Carmel Mothersill; Géza Safrany; Sisko Salomaa; Boglárka Schilling-Tóth; Antonella Tabocchini; Francesca Antonelli; Jostein Dahle; Valentina Dini; Hargita Hegyesi; George Iliakis; Kamy Kämäräinen; Virpi Launonen; Katalin Lumniczky; Fiona M Lyng; Munira A Kadhim
A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
Katalin Dezső; Hargita Hegyesi; Péter Nagy; Csaba Bödör; Edina Bugyik; Veronika Papp; Géza Sáfrány; Sándor Paku
Structural analysis of oval-cell-mediated liver regeneration in rats.

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All Publications

2013: Andrea Balogh; Anett Benedek; Enikő Noémi Bogdándi; Hargita Hegyesi; Eszter Persa; Géza Sáfrány; Katalin Lumniczky
The effect of ionizing radiation on the homeostasis and functional integrity of murine splenic regulatory T cells.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013;62(2):201-12.
2012: Carmel Mothersill; Géza Safrany; Sisko Salomaa; Boglárka Schilling-Tóth; Antonella Tabocchini; Francesca Antonelli; Jostein Dahle; Valentina Dini; Hargita Hegyesi; George Iliakis; Kamy Kämäräinen; Virpi Launonen; Katalin Lumniczky; Fiona M Lyng; Munira A Kadhim
A laboratory inter-comparison of the importance of serum serotonin levels in the measurement of a range of radiation-induced bystander effects: overview of study and results presentation.
International journal of radiation biology 2012;88(10):763-9.
2012: Katalin Dezső; Hargita Hegyesi; Péter Nagy; Csaba Bödör; Edina Bugyik; Veronika Papp; Géza Sáfrány; Sándor Paku
Structural analysis of oval-cell-mediated liver regeneration in rats.
Hepatology (Baltimore, Md.) 2012;56(4):1457-67.
2008: Zoltan Pos; Zoltan Wiener; Peter Pocza; Melinda Racz; Sara Toth; Zsuzsa Darvas; Viktor Molnar; Hargita Hegyesi; András Falus
Histamine suppresses fibulin-5 and insulin-like growth factor-II receptor expression in melanoma.
Cancer research 2008;68(6):1997-2005.
2007: Andreas Costa; Hicham Dalloul; Hargita Hegyesi; Péter Apor; Zsolt Csende; Levente Racz; Mark Vaczi; József Tihanyi
Impact of repeated bouts of eccentric exercise on myogenic gene expression.
European journal of applied physiology 2007;101(4):427-36.
2007: Hargita Hegyesi; Lucas Colombo; Eva Pállinger; Sára Tóth; Katalin Boer; Viktor Molnár; András Falus
Impact of systemic histamine deficiency on the crosstalk between mammary adenocarcinoma and T cells.
Journal of pharmacological sciences 2007;105(1):66-73.
2007: Hargita Hegyesi; Sára Tóth; Viktor Molnár; Katalin Fülöp; András Falus
Endogenous and exogenous histamine influences on angiogenesis related gene expression of mice mammary adenocarcinoma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2007;56 Suppl 1():S37-8.
2005: Béla Horváth; Hargita Hegyesi; Pál Nagy; András Falus; Zsuzsa Schaff
Expression of ets-1 transcription factor in human head and neck squamous cell carcinoma and effect of histamine on metastatic potential of invasive tumor through the regulation of expression of ets-1 and matrix metalloproteinase-3.
Head & neck 2005;27(7):585-96.
2005: Zoltán Pós; Géza Sáfrány; Kerstin Müller; Sára Tóth; András Falus; Hargita Hegyesi
Phenotypic profiling of engineered mouse melanomas with manipulated histamine production identifies histamine H2 receptor and rho-C as histamine-regulated melanoma progression markers.
Cancer research 2005;65(10):4458-66.
2005: Hargita Hegyesi; Béla Horváth; Eva Pállinger; Zoltán Pós; Viktor Molnár; András Falus
Histamine elevates the expression of Ets-1, a protooncogen in human melanoma cell lines through H2 receptor.
FEBS letters 2005;579(11):2475-9.
2004: Hargita Hegyesi; Zsuzsa Darvas; V László; Zoltán Pós; Eva Pállinger; Kristóf Hirschberg; Péter Kovács; András Falus
Retinoic acid enhances histamine content and H1 receptor expression in human neuroblastoma cell line Paju.
Anticancer research 2004;24(3a):1657-63.
2003: Katalin Burián; Hargita Hegyesi; Edit Buzás; Valéria Endrész; Zsolt Kis; András Falus; Eva Gönczöl
Chlamydophila (Chlamydia) pneumoniae induces histidine decarboxylase production in the mouse lung.
Immunology letters 2003;89(2-3):229-36.
2003: Zsuzsa Darvas; Eiko Sakurai; Hubert G Schwelberger; Hargita Hegyesi; Elena Rivera; Hiroshi Othsu; Takehiko Watanabe; Eva Pállinger; András Falus
Autonomous histamine metabolism in human melanoma cells.
Melanoma research 2003;13(3):239-46.
2002: Eszter Lazar-Molnar; Hargita Hegyesi; Eva Pállinger; Péter Kovács; Sára Tóth; Carlos P Fitzsimons; Graciela Cricco; G Martin; Rosa Bergoc; Zsuzsa Darvas; Elena S Rivera; András Falus
Inhibition of human primary melanoma cell proliferation by histamine is enhanced by interleukin-6.
European journal of clinical investigation 2002;32(10):743-9.
2002: Marianna Holub; Hargita Hegyesi; Péter Igaz; Anna Polgár; Sára Tóth; András Falus
Soluble interleukin-6 receptor enhanced by oncostatin M induces major changes in gene expression profile of human hepatoma cells.
Immunology letters 2002;82(1-2):79-84.
2002: Nóra Szincsák; Hargita Hegyesi; János Hunyadi; G Martin; Eszter Lazar-Molnar; Péter Kovács; E Rivera; András Falus; István Juhász
Cimetidine and a tamoxifen derivate reduce tumour formation in SCID mice xenotransplanted with a human melanoma cell line.
Melanoma research 2002;12(3):231-40.
2002: L Keresztury; András Lászik; Hargita Hegyesi; András Falus
DNA profiling by detection of repetitive nucleotide sequences on human chromosome 6.
Acta biologica Hungarica 2002;53(4):495-8.
2002: Tímea Borbás; Hargita Hegyesi
[Huntington chorea: genetics and biochemistry, diagnosis and therapy].
Acta pharmaceutica Hungarica 2002;72(2):127-36.
2002: Nóra Szincsák; Hargita Hegyesi; János Hunyadi; András Falus; István Juhász
Different h2 receptor antihistamines dissimilarly retard the growth of xenografted human melanoma cells in immunodeficient mice.
Cell biology international 2002;26(9):833-6.
2001: András Falus; Hargita Hegyesi; Eszter Lazar-Molnar; Zoltán Pós; V László; Zsuzsa Darvas
Paracrine and autocrine interactions in melanoma: histamine is a relevant player in local regulation.
Trends in immunology 2001;22(12):648-52.
2001: V László; Gregor Rothe; Hargita Hegyesi; Júlia Szeberényi; Evelyn Orsó; Gerd Schmitz; András Falus
Increased histidine decarboxylase expression during in vitro monocyte maturation; a possible role of endogenously synthesised histamine in monocyte/macrophage differentiation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50(8):428-34.
2001: Hargita Hegyesi; Beáta Somlai; Viktor Varga; G Toth; Péter Kovács; Eszter Lazar-Molnar; V Laszlo; Sarolta Kárpáti; Elena Rivera; András Falus; Zsuzsa Darvas
Suppression of melanoma cell proliferation by histidine decarboxylase specific antisense oligonucleotides.
The Journal of investigative dermatology 2001;117(1):151-3.
2001: Eszter Lazar-Molnar; Graciela Cricco; G Martin; Zsuzsa Darvas; Hargita Hegyesi; Carlos P Fitzsimons; Rosa Bergoc; András Falus; Elena Rivera
Histamine as a potential autocrine regulator of melanoma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2001;50 Suppl 2():S102-3.
2000: Mary Haak-Frendscho; Zsuzsa Darvas; Hargita Hegyesi; Sarolta Kárpáti; R L Hoffman; V László; M Bencsáth; Csaba Szalai; József Fürész; Júlia Timár; Z Bata-Csörgõ; Gábor Szabad; Andor Pivarcsi; Eva Pállinger; Lajos Kemeny; Attila Horváth; Attila Dobozy; András Falus
Histidine decarboxylase expression in human melanoma.
The Journal of investigative dermatology 2000;115(3):345-52.
2000: E Heninger; András Falus; Zsuzsa Darvas; Csaba Szalai; M Zsinkó; Z Pos; Hargita Hegyesi
Both interferon (IFN)alpha and IFNgamma inhibit histidine decarboxylase expression in the HT168 human melanoma cell line.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49(8):393-7.
2000: Eszter Lazar-Molnar; Hargita Hegyesi; Sára Tóth; András Falus
Autocrine and paracrine regulation by cytokines and growth factors in melanoma.
Cytokine 2000;12(6):547-54.
2000: Zsuzsa Darvas; E Sakurai; Hargita Hegyesi; H Otsu; Takehiko Watanabe; András Falus
Turnover of histamine in human melanoma cell lines.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49 Suppl 1():S70-1.
2000: Béla Horváth; E Heninger; Hargita Hegyesi; Eszter Lazar-Molnar; Z Radvány; Csaba Szalai; Zsuzsa Darvas; András Falus
Reciprocal inhibitory interactions between interferon gamma and histamine in melanoma.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2000;49 Suppl 1():S27-8.
2000: Eszter Lazar-Molnar; Hargita Hegyesi; Sára Tóth; Zsuzsa Darvas; V László; Csaba Szalai; András Falus
Biosynthesis of interleukin-6, an autocrine growth factor for melanoma, is regulated by melanoma-derived histamine.
Seminars in cancer biology 2000;10(1):25-8.
1999: Hargita Hegyesi; Csaba Szalai; András Falus; György Csaba
The histidine decarboxylase (HDC) gene of Tetrahymena pyriformis is similar to the mammalian one. A study of HDC expression.
Bioscience reports 1999;19(2):73-9.
1999: V László; J Stöhr; Hargita Hegyesi; Gregor Rothe; Evelyn Orsó; András Falus; Gerd Schmitz
Increase of histidine decarboxylase in human monocytes during macrophage colony stimulating factor induced in vitro phagocytic differentiation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1999;48 Suppl 1():S85-6.
1999: Péter Kovács; Hargita Hegyesi; Lászlo Köhidai; P Nemes; György Csaba
Effect of C2 ceramide on the inositol phospholipid metabolism (uptake of 32P, 3H-serine and 3H-palmitic acid) and apoptosis-related morphological changes in Tetrahymena.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1999;122(2):215-24.
1999: András K Fülöp; Hargita Hegyesi
Non-conventional locations of hormone receptors (binding sites). A review.
Acta biologica Hungarica 1999;50(4):343-54.
1998: Hargita Hegyesi; Péter Kovács; András Falus; György Csaba
Presence and localization of histidine decarboxylase enzyme (HDC) and histamine in Tetrahymena pyriformis.
Cell biology international 1998;22(7-8):493-7.
1997: Hargita Hegyesi; György Csaba
Time- and concentration-dependence of the growth-promoting activity of insulin and histamine in Tetrahymena. Application of the MTT-method for the determination of cell proliferation in a protozoan model.
Cell biology international 1997;21(5):289-93.
1997: András Falus; V László; Z Radvány; Hargita Hegyesi; B Kiss; M Bencsáth; Zsuzsa Darvas
Histidine decarboxylase and intracellular histamine in melanoma cells and in a T cell line.
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 1997;46 Suppl 1():S51-2.
1994: Hargita Hegyesi; György Csaba
A calcium-dependent protein kinase is present in tetrahymena.
Cell biochemistry and function 1994;12(3):221-6.
1994: György Csaba; Hargita Hegyesi
Immunocytochemical verification of the insulin receptor's specificity in the nuclear envelope of Tetrahymena. Comparison with receptors of the plasma membrane.
Bioscience reports 1994;14(1):25-31.
1994: Hargita Hegyesi; György Csaba
Change in insulin binding capacity of plasma membrane and nuclear envelope of Tetrahymena following a single long-term pretreatment and several short-term pretreatments (imprinting) with insulin.
Cytobios 1994;79(318):189-94.
1994: Hargita Hegyesi; György Csaba
Effect of permanent starvation on the insulin receptors of the nuclear envelope of Tetrahymena.
Acta microbiologica et immunologica Hungarica 1994;41(3):241-5.
1993: György Csaba; Hargita Hegyesi
The role of receptors of the plasma membrane and nuclear envelope in the failure of insulin imprinting in starving Tetrahymena.
Acta microbiologica Hungarica 1993;40(2):101-5.
1992: Péter Kovács; Hargita Hegyesi; György Csaba
Effect of vanadate and ouabain on insulin binding and insulin imprinting in Tetrahymena.
Cell biochemistry and function 1992;10(1):31-4.
1992: György Csaba; Hargita Hegyesi
Specificity of insulin binding by plasma and nuclear membrane receptors in Tetrahymena: similarities and dissimilarities at the two levels.
Cytobios 1992;70(282-283):153-8.
1992: Hargita Hegyesi; Péter Kovács; György Csaba
Chloroquine inhibits the insulin binding and the imprinting of nuclear envelope in Tetrahymena.
Acta microbiologica Hungarica 1992;39(3-4):289-93.
1992: Hargita Hegyesi; György Csaba
Effect of pretreatments (imprinting) with different concentrations of insulin on insulin binding of nuclear envelope and plasma membrane in Tetrahymena.
Cytobios 1992;72(290-291):191-6.
1992: Hargita Hegyesi; György Csaba
Specific insulin binding by, and imprintability of, the nuclear membrane of Tetrahymena.
Cytobios 1992;72(290-291):153-7.
1992: György Csaba; Hargita Hegyesi; O Török
Impact of combined hormonal pretreatment (insulin+TSH) on the imprinting of hormones administered in combination to Chinese hamster ovary cell culture.
Acta physiologica Hungarica 1992;79(1):65-72.
1992: György Csaba; Hargita Hegyesi; O Török
Impact of serum concentration of the medium and fasting on the imprintability of the insulin receptors of Chang liver cells.
Acta physiologica Hungarica 1992;79(2):213-7.