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Axel Heimann

Research Profile

Living Beings

Physiology

Disorders

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Laser-Doppler Flowmetry

Anatomy

Chemicals & Drugs

Phenomena

Cortical Spreading Depression

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TOP 3
Heinz-Georg Jahnke; Oliver Kempski; Konstantinos Mpoukouvalas; Andrea A Robitzki; Ronny Azendorf; Axel Heimann; Patra Charalampaki
Impedance spectroscopy-An outstanding method for label-free and real-time discrimination between brain and tumor tissue in vivo.
T Inui; Beat Alessandri; K Frauenknecht; Axel Heimann; F Nishimura; C Sommer; Oliver Kempski
Neuroprotective effect of ceftriaxone on the penumbra in a rat venous ischemia model.
M Rahimi Nedjat; H Vatter; M Wähmann; H Bächli; E Güresir; Axel Heimann; Oliver Kempski; A Raabe; Beat Alessandri
Erythropoietin neuroprotection is enhanced by direct cortical application following subdural blood evacuation in a rat model of acute subdural hematoma.

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2013: Heinz-Georg Jahnke; Oliver Kempski; Konstantinos Mpoukouvalas; Andrea A Robitzki; Ronny Azendorf; Axel Heimann; Patra Charalampaki
Impedance spectroscopy-An outstanding method for label-free and real-time discrimination between brain and tumor tissue in vivo.
Biosensors & bioelectronics 2013;46():8-14.
2013: T Inui; Beat Alessandri; K Frauenknecht; Axel Heimann; F Nishimura; C Sommer; Oliver Kempski
Neuroprotective effect of ceftriaxone on the penumbra in a rat venous ischemia model.
Neuroscience 2013;242():1-10.
2013: M Rahimi Nedjat; H Vatter; M Wähmann; H Bächli; E Güresir; Axel Heimann; Oliver Kempski; A Raabe; Beat Alessandri
Erythropoietin neuroprotection is enhanced by direct cortical application following subdural blood evacuation in a rat model of acute subdural hematoma.
Neuroscience 2013;238():125-34.
2012: Iris Riemann; Axel Heimann; Oliver Kempski; Ronan Le Harzic; Konstantinos Mpoukouvalas; Patra Charalampaki
Sub-cellular tumor identification and markerless differentiation in the rat brain in vivo by multiphoton microscopy.
Lasers in surgery and medicine 2012;44(9):719-25.
2012: Beat Alessandri; Axel Heimann; Yoshitaka Kamada; Momoko Nagata; Eike Schwandt; Oliver Kempski
The neuroprotective effect of lactate is not due to improved glutamate uptake after controlled cortical impact in rats.
Journal of neurotrauma 2012;29(12):2181-91.
2012: Sebastian Foersch; Martin Goetz; Axel Heimann; Oliver Kempski; Ralf Kiesslich; Konstantin Mpoukouvalas; Gilles A Spoden; Ali Ayyad; Luise Florin; Patra Charalampaki
Confocal laser endomicroscopy for diagnosis and histomorphologic imaging of brain tumors in vivo.
PloS one 2012;7(7):e41760.
2012: Takanobu Kaido; Oliver Kempski; Cara Heers; Axel Heimann; Daniela Bartsch
Cluster analysis of mRNA expression levels identifies multiple sequential patterns following focal cerebral ischemia.
Turkish neurosurgery 2012;22(4):441-7.
2012: Beat Alessandri; Axel Heimann; J Stephan Tretzel; Oliver Kempski
Spontaneous cortical spreading depression and intracranial pressure following acute subdural hematoma in a rat.
Acta neurochirurgica. Supplement 2012;114():373-6.
2011: A Meissner; R Timaru-Kast; Axel Heimann; Bernd Manfred Hoelper; Oliver Kempski; Beat Alessandri
Effects of a small acute subdural hematoma following traumatic brain injury on neuromonitoring, brain swelling and histology in pigs.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2011;47(3):141-53.
2011: Werner Kneist; D W Kauff; K P Koch; I Schmidtmann; Axel Heimann; K P Hoffmann; Hauke Lang
Selective pelvic autonomic nerve stimulation with simultaneous intraoperative monitoring of internal anal sphincter and bladder innervation.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2011;46(3):133-8.
2010: Werner Kneist; Daniel W Kauff; Roman K Rahimi Nedjat; Andreas D Rink; Axel Heimann; Karin Somerlik; Klaus P Koch; Thomas Doerge; Hauke Lang
Intraoperative pelvic nerve stimulation performed under continuous electromyography of the internal anal sphincter.
International journal of colorectal disease 2010;25(11):1325-31.
2010: Dirk Ernst Johannes Cleppien; Georg Horstick; Nico Abegunewardene; Stefan Weber; Christian Ernst Müller; Axel Heimann; Karl-Friedrich Kreitner; Oliver Kempski; Laura Maria Schreiber
Comparison of the quantitative first pass myocardial perfusion MRI with and without prospective slice tracking: comparison between breath-hold and free-breathing condition.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2010;64(5):1461-70.
2010: Igor Yakushev; Erwan Dupont; Hans-Georg Buchholz; Julia Tillmanns; Fabian Debus; Paul Cumming; Axel Heimann; Andreas Fellgiebel; Heiko J Luhmann; Christian Landvogt; Konrad J Werhahn; Mathias Schreckenberger; Heidrun Potschka; Peter Bartenstein
In vivo imaging of dopamine receptors in a model of temporal lobe epilepsy.
Epilepsia 2010;51(3):415-22.
2009: Fabian Büttner; Christian Cordes; Frank Gerlach; Axel Heimann; Beat Alessandri; Ulrich Luxemburger; Ozlem Türeci; Thomas Hankeln; Oliver Kempski; Thorsten Burmester
Genomic response of the rat brain to global ischemia and reperfusion.
Brain research 2009;1252():1-14.
2008: Ralph Timaru-Kast; Anke Meissner; Axel Heimann; Bernd Hoelper; Oliver Kempski; Beat Alessandri
Acute subdural hematoma in pigs: role of volume on multiparametric neuromonitoring and histology.
Journal of neurotrauma 2008;25(9):1107-19.
2008: Patra Charalampaki; Axel Heimann; Laszlo Kopacz; Ronald Filippi; Islam Gawish; Axel Perneczky; Oliver Kempski
New method of bone reconstruction designed for skull base surgery.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2008;15(6):679-85.
2008: Daniel Jussen; Chrysostomos Papaioannou; Axel Heimann; Oliver Kempski; Beat Alessandri
Effects of hypertonic/hyperoncotic treatment and surgical evacuation after acute subdural hematoma in rats.
Critical care medicine 2008;36(2):543-9.
2008: Martin Goetz; S Thomas; Axel Heimann; Peter M Delaney; C Schneider; M Relle; Andreas Schwarting; Peter R Galle; Oliver Kempski; Markus F Neurath; Steven Thomas
Dynamic in vivo imaging of microvasculature and perfusion by miniaturized confocal laser microscopy.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2008;41(3):290-7.
2008: Patra Charalampaki; Axel Heimann; Ralf Kockro; Wolfgang Kohnen; Oliver Kempski
A new model of skull base reconstruction following expanded endonasal or transoral approaches--long-term results in primates.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2008;41(2):208-13.
2008: Benjamin Bierbach; Matthias Meier; Walter Kasper-König; Axel Heimann; Beat Alessandri; Georg Horstick; Hellmut Oelert; Oliver Kempski
Emboli formation rather than inflammatory mediators are responsible for increased cerebral water content after conventional and assisted beating-heart myocardial revascularization in a porcine model.
Stroke; a journal of cerebral circulation 2008;39(1):213-9.
2007: Max Nedelmann; Thomas Wilhelm-Schwenkmezger; Beat Alessandri; Axel Heimann; Felicitas Schneider; B Martin Eicke; Marianne Dieterich; Oliver Kempski
Cerebral embolic ischemia in rats: correlation of stroke severity and functional deficit as important outcome parameter.
Brain research 2007;1130(1):188-96.
2006: Beat Alessandri; T Nishioka; Axel Heimann; Ross Bullock; Oliver Kempski
Caspase-dependent cell death involved in brain damage after acute subdural hematoma in rats.
Brain research 2006;1111(1):196-202.
2006: Ruediger Noppens; Michael Christ; Ansgar M Brambrink; Ines P Koerner; Axel Heimann; Oliver Kempski
An early bolus of hypertonic saline hydroxyethyl starch improves long-term outcome after global cerebral ischemia.
Critical care medicine 2006;34(8):2194-200.
2006: Benjamin Bierbach; Georg Horstick; Oliver Berg; Axel Heimann; Thomas Münzel; Christian F Vahl; Oliver Kempski; Harald Darius
Potent low dose platelet inhibitory effects of clopidogrel and aspirin on coronary thrombus formation in an animal model of acute unstable angina.
Thrombosis and haemostasis 2006;95(2):354-61.
2005: Ichiro Nakagawa; Beat Alessandri; Axel Heimann; Oliver Kempski
MitoKATP-channel opener protects against neuronal death in rat venous ischemia.
Neurosurgery 2005;57(2):334-40; discussion 334-40.
2005: Michael Lauterbach; Georg Horstick; Nicola Plum; Axel Heimann; Dietmar Becker; Ludwig Sacha Weilemann; Thomas Münzel; Oliver Kempski
Prolonged recirculation is required to detect secondary metabolic and hemodynamic deterioration after superior mesenteric artery occlusion.
Clinical hemorheology and microcirculation 2005;32(1):1-12.
2004: Ansgar M Brambrink; H Noga; A Astheimer; Axel Heimann; Oliver Kempski
Pharmacological preconditioning in global cerebral ischemia.
Acta neurochirurgica. Supplement 2004;89():63-6.
2003: Beat Alessandri; Axel Heimann; Ronald Filippi; Laszlo Kopacz; Oliver Kempski
Moderate controlled cortical contusion in pigs: effects on multi-parametric neuromonitoring and clinical relevance.
Journal of neurotrauma 2003;20(12):1293-305.
2003: T Kaido; Axel Heimann; Oliver Kempski
Novel complement C1 inhibitor BSF468248 does not improve brain damage after cortical vein occlusion.
Methods and findings in experimental and clinical pharmacology 2003;25(8):611-6.
2003: Axel Heimann; T Takeshima; Beat Alessandri; Ruediger Noppens; Oliver Kempski
Effects of hypertonic/hyperoncotic treatment after rat cortical vein occlusion.
Critical care medicine 2003;31(10):2495-501.
2002: Max Nedelmann; B Martin Eicke; Ernst G Lierke; Axel Heimann; Oliver Kempski; Hanns C Hopf
Low-frequency ultrasound induces nonenzymatic thrombolysis in vitro.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 2002;21(6):649-56.
2002: Georg Horstick; Michael Lauterbach; Tibor Kempf; Sucharit Bhakdi; Axel Heimann; Marina Horstick; Jürgen Meyer; Oliver Kempski
Early albumin infusion improves global and local hemodynamics and reduces inflammatory response in hemorrhagic shock.
Critical care medicine 2002;30(4):851-5.
2001: Georg Horstick; Oliver Berg; Axel Heimann; O Götze; Michael Loos; Gerd Hafner; Benjamin Bierbach; S Petersen; Sucharit Bhakdi; Harald Darius; Marina Horstick; Jürgen Meyer; Oliver Kempski
Application of C1-esterase inhibitor during reperfusion of ischemic myocardium: dose-related beneficial versus detrimental effects.
Circulation 2001;104(25):3125-31.
2001: Georg Horstick; Tibor Kempf; Michael Lauterbach; Sucharit Bhakdi; Laszlo Kopacz; Axel Heimann; M Malzahn; Marina Horstick; Jürgen Meyer; Oliver Kempski
C1-esterase-inhibitor treatment at early reperfusion of hemorrhagic shock reduces mesentry leukocyte adhesion and rolling.
Microcirculation (New York, N.Y. : 1994) 2001;8(6):427-33.
2001: J Tuettenberg; Axel Heimann; Oliver Kempski
Nitric oxide modulates cerebral blood flow stimulation by acetazolamide in the rat cortex: a laser Doppler scanning study.
Neuroscience letters 2001;315(1-2):65-8.
2001: M Soehle; Axel Heimann; Oliver Kempski
On the number of measurement sites required to assess regional cerebral blood flow by laser-Doppler scanning during cerebral ischemia and reperfusion.
Journal of neuroscience methods 2001;110(1-2):91-4.
2001: Georg Horstick; Michael Lauterbach; Tibor Kempf; M Ossendorf; Laszlo Kopacz; Axel Heimann; Hans-Anton Lehr; Sucharit Bhakdi; Marina Horstick; Jürgen Meyer; Oliver Kempski
Plasma protein loss during surgery: beneficial effects of albumin substitution.
Shock (Augusta, Ga.) 2001;16(1):9-14.
2001: M Proescholdt; Axel Heimann; Oliver Kempski
Neuroprotection of S(+) ketamine isomer in global forebrain ischemia.
Brain research 2001;904(2):245-51.
2000: Georg Horstick; Tibor Kempf; Michael Lauterbach; M Ossendorf; Laszlo Kopacz; Axel Heimann; Hans-Anton Lehr; Sucharit Bhakdi; Jürgen Meyer; Oliver Kempski
Plastic foil technique attenuates inflammation in mesenteric intravital microscopy.
The Journal of surgical research 2000;94(1):28-34.
2000: Ansgar M Brambrink; Armin Schneider; H Noga; A Astheimer; B Götz; I Körner; Axel Heimann; M Welschof; Oliver Kempski
Tolerance-Inducing dose of 3-nitropropionic acid modulates bcl-2 and bax balance in the rat brain: a potential mechanism of chemical preconditioning.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(10):1425-36.
2000: HG Boecher-Schwarz; Kurt Ringel; Laszlo Kopacz; Axel Heimann; Oliver Kempski
Ex vivo study of the physical effect of coils on pressure and flow dynamics in experimental aneurysms.
AJNR. American journal of neuroradiology 2000;21(8):1532-6.
2000: H Nakase; Axel Heimann; R Uranishi; M W Riepe; Oliver Kempski
Early-onset tolerance in rat global cerebral ischemia induced by a mitochondrial inhibitor.
Neuroscience letters 2000;290(2):105-8.
2000: Ronald Filippi; A Derdilopoulos; Axel Heimann; F Krummenauer; Axel Perneczky; Oliver Kempski
Tightness of duraplasty in rabbits: a comparative study.
Neurosurgery 2000;46(6):1470-6; discussion 1476-7.
2000: Stefan-Nikolaus Kroppenstedt; P Ulrich; Axel Heimann; Oliver Kempski
Significance of resting and stimulated cerebral blood flow for predicting the risk of hemodynamic cerebral ischemia in a model of chronic hemodynamic insufficiency.
Neurosurgery 2000;46(5):1204-10; discussion 1210-2.
2000: H Otsuka; K Ueda; Axel Heimann; Oliver Kempski
Effects of cortical spreading depression on cortical blood flow, impedance, DC potential, and infarct size in a rat venous infarct model.
Experimental neurology 2000;162(1):201-14.
2000: Oliver Kempski; H Otsuka; T Seiwert; Axel Heimann
Spreading depression induces permanent cell swelling under penumbra conditions.
Acta neurochirurgica. Supplement 2000;76():251-5.
2000: M Soehle; Axel Heimann; Oliver Kempski
Laser Doppler scanning: how many measurements are required to assess regional cerebral blood flow?
Acta neurochirurgica. Supplement 2000;76():181-4.
1999: Ansgar M Brambrink; Laszlo Kopacz; A Astheimer; H Noga; Axel Heimann; Oliver Kempski
Control of brain temperature during experimental global ischemia in rats.
Journal of neuroscience methods 1999;92(1-2):111-22.
1999: Axel Heimann; T Takeshima; Georg Horstick; Oliver Kempski
C1-esterase inhibitor reduces infarct volume after cortical vein occlusion.
Brain research 1999;838(1-2):210-3.
1999: Georg Horstick; Oliver Berg; Axel Heimann; Harald Darius; Hans-Anton Lehr; Sucharit Bhakdi; Oliver Kempski; Jürgen Meyer
Surgical procedure affects physiological parameters in rat myocardial ischemia: need for mechanical ventilation.
The American journal of physiology 1999;276(2 Pt 2):H472-9.
1999: Oliver Kempski; T Seiwert; H Otsuka; Axel Heimann; H Nakase
Modelling of the ischemic penumbra.
Acta neurochirurgica. Supplement 1999;73():41-4.
1998: P T Ulrich; Stefan-Nikolaus Kroppenstedt; Axel Heimann; Oliver Kempski
Laser-Doppler scanning of local cerebral blood flow and reserve capacity and testing of motor and memory functions in a chronic 2-vessel occlusion model in rats.
Stroke; a journal of cerebral circulation 1998;29(11):2412-20.
1998: M Soehle; Axel Heimann; Oliver Kempski
Postischemic application of lipid peroxidation inhibitor U-101033E reduces neuronal damage after global cerebral ischemia in rats.
Stroke; a journal of cerebral circulation 1998;29(6):1240-6; discussion 1246-7.
1998: H Nakase; T Takeshima; T Sakaki; Axel Heimann; Oliver Kempski
Superior sagittal sinus thrombosis: a clinical and experimental study.
Skull base surgery 1998;8(4):169-74.
1997: Oliver Kempski; Axel Heimann; H Nakase
[Biochemical brain protection].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1997;32(2 Suppl):S286-90.
1997: H Nakase; Oliver Kempski; Axel Heimann; T Takeshima; Jaroslav Tintera
Microcirculation after cerebral venous occlusions as assessed by laser Doppler scanning.
Journal of neurosurgery 1997;87(2):307-14.
1997: Georg Horstick; Axel Heimann; O Götze; Gerd Hafner; Oliver Berg; P Böhmer; P Becker; Harald Darius; Hans J Rupprecht; Michael Loos; Sucharit Bhakdi; Jürgen Meyer; Oliver Kempski
Intracoronary application of C1 esterase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion.
Circulation 1997;95(3):701-8.
1996: H Nakase; Axel Heimann; Oliver Kempski
Local cerebral blood flow in a rat cortical vein occlusion model.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1996;16(4):720-8.
1996: Karl Ungersböck; Axel Heimann; Oliver Kempski
Monitoring of cortical blood flow: clinical relevance of experimental laser Doppler studies.
Neurological research 1996;18(3):273-6.
1996: H Nakase; Axel Heimann; Oliver Kempski
Alterations of regional cerebral blood flow and oxygen saturation in a rat sinus-vein thrombosis model.
Stroke; a journal of cerebral circulation 1996;27(4):720-7; discussion 728.
1996: Oliver Kempski; C Obert; T Mainka; Axel Heimann; U Strecker
"Small volume resuscitation" as treatment of cerebral blood flow disturbances and increased ICP in trauma and ischemia.
Acta neurochirurgica. Supplement 1996;66():114-7.
1996: J Jonas; Axel Heimann; A Alebrahim-Dehkordy; Oliver Kempski
[Reperfusion shock after occlusion of the superior mesenteric artery and accumulation of leukocytes within the wall of the small intestine].
Langenbecks Archiv für Chirurgie 1996;381(2):95-101.
1995: Karl Ungersböck; D Tenckhoff; Axel Heimann; W Wagner; Oliver Kempski
Transcranial Doppler and cortical microcirculation at increased intracranial pressure and during the Cushing response: an experimental study on rabbits.
Neurosurgery 1995;36(1):147-56; discussion 156-7.
1995: Oliver Kempski; Axel Heimann; U Strecker
On the number of measurements necessary to assess regional cerebral blood flow by local laser Doppler recordings: a simulation study with data from 45 rabbits.
International journal of microcirculation, clinical and experimental / sponsored by the European Society for Microcirculation 1995;15(1):37-42.
1994: Axel Heimann; S Kroppenstedt; P Ulrich; Oliver Kempski
Cerebral blood flow autoregulation during hypobaric hypotension assessed by laser Doppler scanning.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):1100-5.
1994: Andreas Leunig; F Staub; J Peters; Axel Heimann; C Csapo; Oliver Kempski; Alwin E Goetz
Relation of early Photofrin uptake to photodynamically induced phototoxicity and changes of cell volume in different cell lines.
European journal of cancer (Oxford, England : 1990) 1994;30A(1):78-83.
1993: Walter Stummer; C Götz; A Hassan; Axel Heimann; Oliver Kempski
Kinetics of Photofrin II in perifocal brain edema.
Neurosurgery 1993;33(6):1075-81; discussion 1081-2.
1993: Karl Ungersböck; Axel Heimann; Oliver Kempski
Cerebral blood flow alterations in a rat model of cerebral sinus thrombosis.
Stroke; a journal of cerebral circulation 1993;24(4):563-9; discussion 569-70.
1993: Andreas Leunig; F Staub; J Peters; Axel Heimann; Oliver Kempski; Alwin E Goetz
An in vitro model to study cellular photosensitizer uptake and photodynamic dose-response relationships of tumor cells.
Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1993;193(6):361-70.
1992: Georg Fries; T Wallenfang; J Hennen; M Velthaus; Axel Heimann; H Schild; Axel Perneczky; Oliver Kempski
Occlusion of the pig superior sagittal sinus, bridging and cortical veins: multistep evolution of sinus-vein thrombosis.
Journal of neurosurgery 1992;77(1):127-33.