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Thorsten Heinekamp

Research Profile

Living Beings

Chemicals & Drugs

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Aspergillosis

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Genes, Fungal

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Publications

TOP 3
Daniel H Scharf; Kirstin Scherlach; Martin Roth; Axel A Brakhage; Pranatchareeya Chankhamjon; Thorsten Heinekamp; Christian Hertweck
Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway.
Christian Gil Girol; Stefan Günther; Thorsten Heinekamp; Wolfgang Hüttel; Axel A Brakhage; Katja Maria Fisch; Jörn Piel; Michael Müller
Regio- and stereoselective oxidative phenol coupling in Aspergillus niger.
Thorsten Heinekamp; Sophia Keller; Juliane Macheleidt; Andreas Thywißen; Vito Valiante; Axel A Brakhage
Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.

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All Publications

2012: Daniel H Scharf; Kirstin Scherlach; Martin Roth; Axel A Brakhage; Pranatchareeya Chankhamjon; Thorsten Heinekamp; Christian Hertweck
Epidithiol formation by an unprecedented twin carbon-sulfur lyase in the gliotoxin pathway.
Angewandte Chemie (International ed. in English) 2012;51(40):10064-8.
2012: Christian Gil Girol; Stefan Günther; Thorsten Heinekamp; Wolfgang Hüttel; Axel A Brakhage; Katja Maria Fisch; Jörn Piel; Michael Müller
Regio- and stereoselective oxidative phenol coupling in Aspergillus niger.
Angewandte Chemie (International ed. in English) 2012;51(39):9788-91.
2012: Thorsten Heinekamp; Sophia Keller; Juliane Macheleidt; Andreas Thywißen; Vito Valiante; Axel A Brakhage
Aspergillus fumigatus melanins: interference with the host endocytosis pathway and impact on virulence.
Frontiers in microbiology 2012;3():440.
2012: Fabian Horn; Olaf Kniemeyer; Johannes Pollmächer; Vito Valiante; Thorsten Heinekamp; Axel A Brakhage
Systems biology of fungal infection.
Frontiers in microbiology 2012;3():108.
2011: Dirk Wartenberg; Hans-Martin Dahse; Thorsten Heinekamp; Ilse Jacobsen; Olaf Kniemeyer; Katrin Lapp; Axel A Brakhage
Secretome analysis of Aspergillus fumigatus reveals Asp-hemolysin as a major secreted protein.
International journal of medical microbiology : IJMM 2011;301(7):602-11.
2011: Radhika Jain; Nicole Remme; Vito Valiante; Teresa Docimo; Jonathan Gershenzon; Hubertus Haas; Thorsten Heinekamp; Christian Hertweck; Axel A Brakhage
The MAP kinase MpkA controls cell wall integrity, oxidative stress response, gliotoxin production and iron adaptation in Aspergillus fumigatus.
Molecular microbiology 2011;82(1):39-53.
2011: Daniel H Scharf; Kirstin Scherlach; Peter Hortschansky; Nicole Remme; Axel A Brakhage; Pranatchareeya Chankhamjon; Andreas Habel; Thorsten Heinekamp; Christian Hertweck
A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis.
Journal of the American Chemical Society 2011;133(32):12322-5.
2011: Sophia Keller; Juliane Macheleidt; Kirstin Scherlach; Jeannette Schmaler-Ripcke; Thorsten Heinekamp; Ilse D Jacobsen; Axel A Brakhage
Pyomelanin formation in Aspergillus fumigatus requires HmgX and the transcriptional activator HmgR but is dispensable for virulence.
PloS one 2011;6(10):e26604.
2011: Andreas Thywißen; Peter F Zipfel; Hans-Martin Dahse; Thorsten Heinekamp; Sandor Nietzsche; Jeannette Schmaler-Ripcke; Axel A Brakhage
Conidial Dihydroxynaphthalene Melanin of the Human Pathogenic Fungus Aspergillus fumigatus Interferes with the Host Endocytosis Pathway.
Frontiers in microbiology 2011;2():96.
2010: Daniel H Scharf; Nicole Remme; Thorsten Heinekamp; Peter Hortschansky; Axel A Brakhage; Christian Hertweck
Transannular disulfide formation in gliotoxin biosynthesis and its role in self-resistance of the human pathogen Aspergillus fumigatus.
Journal of the American Chemical Society 2010;132(29):10136-41.
2010: Tim Iven; Anne Strathmann; Stefan Böttner; Thomas Zwafink; Thorsten Heinekamp; Anne Guivarc'h; Thomas Roitsch; Wolfgang Dröge-Laser
Homo- and heterodimers of tobacco bZIP proteins counteract as positive or negative regulators of transcription during pollen development.
The Plant journal : for cell and molecular biology 2010;63(1):155-66.
2010: Alexander Gehrke; Thorsten Heinekamp; Ilse Jacobsen; Axel A Brakhage
Heptahelical receptors GprC and GprD of Aspergillus fumigatus Are essential regulators of colony growth, hyphal morphogenesis, and virulence.
Applied and environmental microbiology 2010;76(12):3989-98.
2010: Markus Schrettl; Nicola Beckmann; John Joseph Varga; Thorsten Heinekamp; Ilse Jacobsen; Christoph Jöchl; Tarek A. A. Moussa; Shaohua Wang; Fabio Gsaller; Michael Blatzer; Ernst R Werner; William C Niermann; Axel A Brakhage; Hubertus Haas
HapX-mediated adaption to iron starvation is crucial for virulence of Aspergillus fumigatus.
PLoS pathogens 2010;6(9):e1001124.
2009: Vito Valiante; Radhika Jain; Thorsten Heinekamp; Axel A Brakhage
The MpkA MAP kinase module regulates cell wall integrity signaling and pyomelanin formation in Aspergillus fumigatus.
Fungal genetics and biology : FG & B 2009;46(12):909-18.
2009: Jeannette Schmaler-Ripcke; Venelina Sugareva; Peter Gebhardt; Robert Winkler; Olaf Kniemeyer; Thorsten Heinekamp; Axel A Brakhage
Production of pyomelanin, a second type of melanin, via the tyrosine degradation pathway in Aspergillus fumigatus.
Applied and environmental microbiology 2009;75(2):493-503.
2008: André Oliveira Mota Júnior; Iran Malavazi; Frederico M Soriani; Thorsten Heinekamp; Ilse Jacobsen; Axel A Brakhage; Marcela Savoldi; Maria Helena S Goldman; Márcia Eliana da Silva Ferreira; Gustavo H Goldman
Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA.
Molecular genetics and genomics : MGG 2008;280(6):483-95.
2008: Markus Schrettl; Heenam Stanley Kim; Martin Eisendle; Claudia Kragl; William C Nierman; Thorsten Heinekamp; Ernst R Werner; Ilse Jacobsen; Paul Illmer; Hyojeong Yi; Axel A Brakhage; Hubertus Haas
SreA-mediated iron regulation in Aspergillus fumigatus.
Molecular microbiology 2008;70(1):27-43.
2008: Christina Grosse; Thorsten Heinekamp; Olaf Kniemeyer; Alexander Gehrke; Axel A Brakhage
Protein kinase A regulates growth, sporulation, and pigment formation in Aspergillus fumigatus.
Applied and environmental microbiology 2008;74(15):4923-33.
2008: Vito Valiante; Thorsten Heinekamp; Radhika Jain; Albert Härtl; Axel A Brakhage
The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response.
Fungal genetics and biology : FG & B 2008;45(5):618-27.
2007: Márcia Eliana da Silva Ferreira; Thorsten Heinekamp; Albert Härtl; Axel A Brakhage; Camile P Semighini; Steven D Harris; Marcela Savoldi; Paula Fagundes de Gouvêa; Maria Helena de Souza Goldman; Gustavo H Goldman
Functional characterization of the Aspergillus fumigatus calcineurin.
Fungal genetics and biology : FG & B 2007;44(3):219-30.
2006: Venelina Sugareva; Albert Härtl; Matthias Brock; Katrin Hübner; Manfred Rohde; Thorsten Heinekamp; Axel A Brakhage
Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster of Aspergillus fumigatus.
Archives of microbiology 2006;186(5):345-55.
2006: Claudio Kupfahl; Thorsten Heinekamp; Gernot Geginat; Thomas Ruppert; Albert Härtl; Holger Hof; Axel A Brakhage
Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model.
Molecular microbiology 2006;62(1):292-302.
2006: Márcia Eliana da Silva Ferreira; Marcia R V Z Kress; Marcela Savoldi; Maria Helena S Goldman; Albert Härtl; Thorsten Heinekamp; Axel A Brakhage; Gustavo H Goldman
The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus.
Eukaryotic cell 2006;5(1):207-11.
2005: André D Schmidt; Thorsten Heinekamp; Markus Matuschek; Burghard Liebmann; Claus Bollschweiler; Axel A Brakhage
Analysis of mating-dependent transcription of Blakeslea trispora carotenoid biosynthesis genes carB and carRA by quantitative real-time PCR.
Applied microbiology and biotechnology 2005;67(4):549-55.
2004: Thorsten Heinekamp; Anne Strathmann; Markus Kuhlmann; Marine Froissard; Axel Müller; Catherine Perrot-Rechenmann; Wolfgang Dröge-Laser
The tobacco bZIP transcription factor BZI-1 binds the GH3 promoter in vivo and modulates auxin-induced transcription.
The Plant journal : for cell and molecular biology 2004;38(2):298-309.
2003: Markus Kuhlmann; Katja Horvay; Anne Strathmann; Thorsten Heinekamp; Ute Fischer; Stefan Böttner; Wolfgang Dröge-Laser
The alpha-helical D1 domain of the tobacco bZIP transcription factor BZI-1 interacts with the ankyrin-repeat protein ANK1 and is important for BZI-1 function, both in auxin signaling and pathogen response.
The Journal of biological chemistry 2003;278(10):8786-94.
2002: Thorsten Heinekamp; Markus Kuhlmann; A Lenk; Anne Strathmann; Wolfgang Dröge-Laser
The tobacco bZIP transcription factor BZI-1 binds to G-box elements in the promoters of phenylpropanoid pathway genes in vitro, but it is not involved in their regulation in vivo.
Molecular genetics and genomics : MGG 2002;267(1):16-26.
2001: Anne Strathmann; Markus Kuhlmann; Thorsten Heinekamp; Wolfgang Dröge-Laser
BZI-1 specifically heterodimerises with the tobacco bZIP transcription factors BZI-2, BZI-3/TBZF and BZI-4, and is functionally involved in flower development.
The Plant journal : for cell and molecular biology 2001;28(4):397-408.