FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Ulrich Heiser

Research Profile

Chemicals & Drugs

Living Beings

Concepts & Ideas

Procedures

Anatomy

Cell Line

Genes & Molecular Sequences

Amino Acid Sequences

Co-author Network

Publications

TOP 3
Holger Cynis; Masato Fujii; Monique Haegele; Ulrich Heiser; Torsten Hoffmann; Astrid Kehlen; Stephan Schilling; Yuichiro Shibazaki; Hiroyuki Yoneyama; Hans-Ulrich Demuth
Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice.
Annelie Hellvard; Roland Jonsson; Katarzyna Maresz; Holger Cynis; Hans-Ulrich Demuth; Sigrid Graubner; Ulrich Heiser; Jan Potempa; Stephan Schilling; Piotr Mydel
Glutaminyl cyclases as novel targets for the treatment of septic arthritis.
Birgit Koch; Stephan Schilling; Michael Wermann; Mirko Buchholz; Ulrich Heiser; Hans-Ulrich Demuth
Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Ulrich Heiser (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Holger Cynis; Masato Fujii; Monique Haegele; Ulrich Heiser; Torsten Hoffmann; Astrid Kehlen; Stephan Schilling; Yuichiro Shibazaki; Hiroyuki Yoneyama; Hans-Ulrich Demuth
Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice.
International journal of experimental pathology 2013;94(3):217-25.
2013: Annelie Hellvard; Roland Jonsson; Katarzyna Maresz; Holger Cynis; Hans-Ulrich Demuth; Sigrid Graubner; Ulrich Heiser; Jan Potempa; Stephan Schilling; Piotr Mydel
Glutaminyl cyclases as novel targets for the treatment of septic arthritis.
The Journal of infectious diseases 2013;207(5):768-77.
2012: Birgit Koch; Stephan Schilling; Michael Wermann; Mirko Buchholz; Ulrich Heiser; Hans-Ulrich Demuth
Probing secondary glutaminyl cyclase (QC) inhibitor interactions applying an in silico-modeling/site-directed mutagenesis approach: implications for drug development.
Chemical biology & drug design 2012;80(6):937-46.
2011: Holger Cynis; Margreet R De Vries; Sabine Berg; Rico Eichentopf; Ernst-Joachim Freyse; Daniel Friedrich; Kathrin Gans; Sigrid Graubner; Monique Haegele; Ulrich Heiser; Isabel Hesse; Torsten Hoffmann; Wolfgang Jagla; Astrid Kehlen; Martin Kleinschmidt; Anke Müller; Paul H A Quax; Jens-Ulrich Rahfeld; Stephan Schilling; Reinhard Sedlmeier; Franziska Seifert; Anett Stephan; Daniela Trautwein; Michael Wermann; Raik Wolf; Ulrich Wollert; Hans-Ulrich Demuth
The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
EMBO molecular medicine 2011;3(9):545-58.
2011: David Ruiz-Carrillo; Stephan Schilling; Milton T Stubbs; Michael Wermann; Ulrich Heiser; Birgit Koch; Hans-Henning Ludwig; Christoph Parthier; Jens-Ulrich Rahfeld; Mirko Buchholz; Tresfore Dambe; Hans-Ulrich Demuth
Structures of glycosylated mammalian glutaminyl cyclases reveal conformational variability near the active center.
Biochemistry 2011;50(28):6280-8.
2009: Mirko Buchholz; Antje Hamann; Susanne Aust; Wolfgang Brandt; Livia Böhme; Torsten Hoffmann; Stephan Schilling; Hans-Ulrich Demuth; Ulrich Heiser
Inhibitors for human glutaminyl cyclase by structure based design and bioisosteric replacement.
Journal of medicinal chemistry 2009;52(22):7069-80.
2008: Yue Xu; Yoshitaka Nakajima; Kiyoshi Ito; Heng Zheng; Hiroshi Oyama; Ulrich Heiser; Torsten Hoffmann; Ulf-Torsten Gärtner; Hans-Ulrich Demuth; Tadashi Yoshimoto
Novel inhibitor for prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis and details of substrate-recognition mechanism.
Journal of molecular biology 2008;375(3):708-19.
2007: Daniel Friedrich; Torsten Hoffmann; Joachim Bär; Michael Wermann; Susanne Manhart; Ulrich Heiser; Hans-Ulrich Demuth
Does human attractin have DP4 activity?
Biological chemistry 2007;388(2):155-62.
2007: Nadine Frerker; Leona Wagner; Raik Wolf; Ulrich Heiser; Torsten Hoffmann; Jens-Ulrich Rahfeld; Jutta Schade; Tim Karl; Hassan Y Naim; Marwan Alfalah; Hans-Ulrich Demuth; Stephan von Hörsten
Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4.
Peptides 2007;28(2):257-68.
2006: Holger Cynis; Stephan Schilling; Mandy Bodnár; Torsten Hoffmann; Ulrich Heiser; Takaomi C Saido; Hans-Ulrich Demuth
Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells.
Biochimica et biophysica acta 2006;1764(10):1618-25.
2006: Suraj Unniappan; Christopher H S McIntosh; Hans-Ulrich Demuth; Ulrich Heiser; R Wolf; Timothy J Kieffer
Effects of dipeptidyl peptidase IV on the satiety actions of peptide YY.
Diabetologia 2006;49(8):1915-23.
2006: Michael Engel; Torsten Hoffmann; Susanne Manhart; Ulrich Heiser; Sylvie CHAMBRE; Robert Huber; Hans-Ulrich Demuth; Wolfram Bode
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
Journal of molecular biology 2006;355(4):768-83.
2006: Mirko Buchholz; Ulrich Heiser; Stephan Schilling; André J Niestroj; Katrin Zunkel; Hans-Ulrich Demuth
The first potent inhibitors for human glutaminyl cyclase: synthesis and structure-activity relationship.
Journal of medicinal chemistry 2006;49(2):664-77.
2005: Stephan Schilling; Holger Cynis; Alex von Bohlen; Torsten Hoffmann; Michael Wermann; Ulrich Heiser; Mirko Buchholz; Katrin Zunkel; Hans-Ulrich Demuth
Isolation, catalytic properties, and competitive inhibitors of the zinc-dependent murine glutaminyl cyclase.
Biochemistry 2005;44(40):13415-24.
2003: Michael Engel; Torsten Hoffmann; Leona Wagner; Michael Wermann; Ulrich Heiser; Reiner Kiefersauer; Robert Huber; Wolfram Bode; Hans-Ulrich Demuth; Hans Brandstetter
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5063-8.
2003: André J Niestroj; Dagmar Schlenzig; Ulrich Heiser; Kerstin Kühn-Wache; Blas Cigic; Michael Werman; Torsten Hoffmann; Bernd Gerhartz; Hans-Ulrich Demuth
Acylated hydroxamates as selective and highly potent inhibitors of dipeptidyl peptidase I.
Advances in experimental medicine and biology 2003;524():339-43.
2002: Jens Rüter; Torsten Hoffmann; Ulrich Heiser; Hans-Ulrich Demuth; Petra C Arck; Burghard F Klapp; Martin Hildebrandt
The expression of T-cell surface antigens CTLA-4, CD26, and CD28 is modulated by inhibition of dipeptidylpeptidase IV (DPP IV, CD26) activity in murine stress-induced abortions.
Cellular immunology 2002;220(2):150-6.
2002: Ingo Schulz; Bernd Gerhartz; Antje Neubauer; Andreas Holloschi; Ulrich Heiser; Mathias Hafner; Hans-Ulrich Demuth
Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition.
European journal of biochemistry / FEBS 2002;269(23):5813-20.
2002: André J Niestroj; Kirstin Feussner; Ulrich Heiser; Pam M Dando; Alan Barrett; Bernd Gerhartz; Hans-Ulrich Demuth
Inhibition of mammalian legumain by Michael acceptors and AzaAsn-halomethylketones.
Biological chemistry 2002;383(7-8):1205-14.
2002: Stephan Schilling; Torsten Hoffmann; Michael Wermann; Ulrich Heiser; Claus Wasternack; Hans-Ulrich Demuth
Continuous spectrometric assays for glutaminyl cyclase activity.
Analytical biochemistry 2002;303(1):49-56.
2001: J Andrew Pospisilik; Simon Hinke; Raymond A Pederson; Torsten Hoffmann; Fred Rosche; Dagmar Schlenzig; K Glund; Ulrich Heiser; Christopher H S McIntosh; Hans-Ulrich Demuth
Metabolism of glucagon by dipeptidyl peptidase IV (CD26).
Regulatory peptides 2001;96(3):133-41.