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Christian Heiss

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Patrick Horn; Claas Hundsdörfer; Malte Kelm; Klaus-Dietrich Kröncke; Nicolas Amabile; Miriam M. Cortese-Krott; Christian Heiss
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
Ulrich Sydlik; Alexander Weissenberg; Joachim Windolf; Andreas Bilstein; Christian Heiss; Malte Kelm; Stefanie Keymel; Ursula Krämer; Matthias Kroker; Jean Krutmann; Adnana Paunel-Görgülü; Henrike Peuschel; Samira Seghrouchni; Klaus Unfried
Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation.
Dominik Schuler; Roberto Sansone; Christian Heiss; Malte Kelm
Is there a role for antioxidants in the treatment of stable angina?

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2013: Patrick Horn; Claas Hundsdörfer; Malte Kelm; Klaus-Dietrich Kröncke; Nicolas Amabile; Miriam M. Cortese-Krott; Christian Heiss
Circulating microparticles carry a functional endothelial nitric oxide synthase that is decreased in patients with endothelial dysfunction.
Journal of the American Heart Association 2013;2(1):e003764.
2013: Ulrich Sydlik; Alexander Weissenberg; Joachim Windolf; Andreas Bilstein; Christian Heiss; Malte Kelm; Stefanie Keymel; Ursula Krämer; Matthias Kroker; Jean Krutmann; Adnana Paunel-Görgülü; Henrike Peuschel; Samira Seghrouchni; Klaus Unfried
Recovery of neutrophil apoptosis by ectoine: a new strategy against lung inflammation.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2013;41(2):433-42.
2013: Dominik Schuler; Roberto Sansone; Christian Heiss; Malte Kelm
Is there a role for antioxidants in the treatment of stable angina?
Current pharmaceutical design 2013;19(9):1601-15.
2012: Miriam M. Cortese-Krott; Martin Feelisch; Christian Heiss; Neil Hogg; Patrick Horn; Thomas Krenz; Christoph Krisp; Klaus-Dietrich Kröncke; Gunter G C Kuhnle; Ana Rodriguez-Mateos; Roberto Sansone; Sivatharsini Thasian-Sivarajah; Dirk Wolters; Malte Kelm
Human red blood cells at work: identification and visualization of erythrocytic eNOS activity in health and disease.
Blood 2012;120(20):4229-37.
2012: Ulrike B Hendgen-Cotta; Malte Kelm; Martina Kropp; Peter Luedike; Jon O Lundberg; Michael Niessen; Christos Rammos; Andreas Schicho; Pia Stock; Matthias Totzeck; Eddie Weitzberg; Christian Heiss; Tienush Rassaf
Dietary nitrate supplementation improves revascularization in chronic ischemia.
Circulation 2012;126(16):1983-92.
2012: Eva S Kehmeier; Malte Kelm; Martina Kropp; Wolfgang Lepper; Marc W Merx; Christian Meyer; Mirja Neizel; Christian Ohmann; Jan Balzer; Christian Heiss; Ulrike B Hendgen-Cotta; Gerd Heusch; Pablo E Verde; Tienush Rassaf
TNF-α, myocardial perfusion and function in patients with ST-segment elevation myocardial infarction and primary percutaneous coronary intervention.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(10):815-27.
2012: Christian Heiss; Ulrike B Hendgen-Cotta; Malte Kelm; Stefanie Keymel; Peter Luedike; Jon O Lundberg; Christian Meyer; Nassim Ayoub; Yvonne Heinen; Matthias Totzeck; Eddie Weitzberg; Tienush Rassaf
Dietary inorganic nitrate mobilizes circulating angiogenic cells.
Free radical biology & medicine 2012;52(9):1767-72.
2012: Roberta R Holt; Christian Heiss; Malte Kelm; Carl L Keen
The potential of flavanol and procyanidin intake to influence age-related vascular disease.
Journal of nutrition in gerontology and geriatrics 2012;31(3):290-323.
2011: Andrea Schanz; Virginia D Winn; Marion Blumenstein; Susan J Fisher; Christian Heiss; Alexandra P Hess; Jan S Kruessel; Michael McMaster; Robyn A North
Pre-eclampsia is associated with elevated CXCL12 levels in placental syncytiotrophoblasts and maternal blood.
European journal of obstetrics, gynecology, and reproductive biology 2011;157(1):32-7.
2011: Javier I Ottaviani; Tony Y Momma; Christian Heiss; Catherine L Kwik-Uribe; Hagen Schroeter; Carl L Keen
The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo.
Free radical biology & medicine 2011;50(2):237-44.
2011: Stefanie Keymel; Thomas Lauer; Tienush Rassaf; Jan Balzer; Yvonne Heinen; Malte Kelm; Christian Heiss
Characterization of macro-and microvascular function and structure in patients with type 2 diabetes mellitus.
American journal of cardiovascular disease 2011;1(1):68-75.
2011: Stephan Langer; Niklas Paulus; Christian Heiss; Thomas A Koeppel; Andreas Greiner; Alexandra Buhl; Thomas Lauer; Maria Kokozidou; Michael J Jacobs; Gabriele A Krombach
Cardiovascular remodeling after AVF surgery in rats assessed by a clinical MRI scanner.
Magnetic resonance imaging 2011;29(1):57-63.
2010: Stephan Langer; Maria Kokozidou; Christian Heiss; Jennifer Kranz; Tina Kessler; Niklas Paulus; Thilo Krüger; Michael J Jacobs; Christina Lente; Thomas A Koeppel
Chronic kidney disease aggravates arteriovenous fistula damage in rats.
Kidney international 2010;78(12):1312-21.
2010: Hagen Schroeter; Christian Heiss; Jeremy P E Spencer; Carl L Keen; Joanne R Lupton; Harold H Schmitz
Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs.
Molecular aspects of medicine 2010;31(6):546-57.
2010: T Rassaf; R Westenfeld; Jan Balzer; Thomas Lauer; Marc W Merx; J Floege; Stephan Steiner; Christian Heiss; Malte Kelm; Christian Meyer
Modulation of peripheral chemoreflex by neurohumoral adaptations after kidney transplantation.
European journal of medical research 2010;15 Suppl 2():83-7.
2010: Christian Heiss; Carl L Keen; Malte Kelm
Flavanols and cardiovascular disease prevention.
European heart journal 2010;31(21):2583-92.
2010: Christian Heiss; Andrea Schanz; Nicolas Amabile; Sarah Jahn; Qiumei Chen; Maelene L Wong; Tienush Rassaf; Yvonne Heinen; Miriam M. Cortese-Krott; William Grossman; Yerem Yeghiazarians; Matthew L Springer
Nitric oxide synthase expression and functional response to nitric oxide are both important modulators of circulating angiogenic cell response to angiogenic stimuli.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(11):2212-8.
2010: Christian Heiss; Sarah Jahn; Melanie Taylor; Wendy May Real; Franca S Angeli; Maelene L Wong; Nicolas Amabile; Megha Prasad; Tienush Rassaf; Javier I Ottaviani; Shirley Mihardja; Carl L Keen; Matthew L Springer; Andrew Boyle; William Grossman; Stanton A Glantz; Hagen Schroeter; Yerem Yeghiazarians
Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease.
Journal of the American College of Cardiology 2010;56(3):218-24.
2010: Stefanie Keymel; Julia Sichwardt; Jan Balzer; Emilia Stegemann; Tienush Rassaf; Petra Kleinbongard; Malte Kelm; Christian Heiss; Thomas Lauer
Characterization of the non-invasive assessment of the cutaneous microcirculation by laser Doppler perfusion scanner.
Microcirculation (New York, N.Y. : 1994) 2010;17(5):358-66.
2010: Christian Heiss; Malte Kelm
Chocolate consumption, blood pressure, and cardiovascular risk.
European heart journal 2010;31(13):1554-6.
2009: Christian Opländer; Christine M Volkmar; Adnana Paunel-Görgülü; Ernst E van Faassen; Christian Heiss; Malte Kelm; Daniel Halmer; Manfred Mürtz; Norbert Pallua; Christoph V Suschek
Whole body UVA irradiation lowers systemic blood pressure by release of nitric oxide from intracutaneous photolabile nitric oxide derivates.
Circulation research 2009;105(10):1031-40.
2009: Christian Heiss; Jan Balzer; Till Hauffe; Sandra Hamada; Emilia Stegemann; Thomas Koeppel; Marc W Merx; Tienush Rassaf; Malte Kelm; Thomas Lauer
Vascular dysfunction of brachial artery after transradial access for coronary catheterization: impact of smoking and catheter changes.
JACC. Cardiovascular interventions 2009;2(11):1067-73.
2009: Nicolas Amabile; Christian Heiss; Vivian Chang; Franca S Angeli; Lloyd Damon; Eddie J Rame; Dana McGlothlin; William Grossman; Teresa De Marco; Yerem Yeghiazarians
Increased CD62e(+) endothelial microparticle levels predict poor outcome in pulmonary hypertension patients.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2009;28(10):1081-6.
2009: Shobha Natarajan; Christian Heiss; Yerem Yeghiazarians; Jeffrey R Fineman; David F Teitel; Theresa A Tacy
Peripheral arterial function in infants and young children with one-ventricle physiology and hypoxemia.
The American journal of cardiology 2009;103(6):862-6.
2008: Thomas Lauer; Christian Heiss; Jan Balzer; Stefanie Keymel; Malte Kelm; Michael Preik; Tienush Rassaf
Resting microvascular resistance and conduit artery tone: relevance to endothelium-dependent flow-mediated dilation.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2008;15(6):677-82.
2008: Jan Balzer; Tienush Rassaf; Christian Heiss; Petra Kleinbongard; Thomas Lauer; Marc W Merx; Nicole Heussen; Heidrun B Gross; Carl L Keen; Hagen Schroeter; Malte Kelm
Sustained benefits in vascular function through flavanol-containing cocoa in medicated diabetic patients a double-masked, randomized, controlled trial.
Journal of the American College of Cardiology 2008;51(22):2141-9.
2008: Nicolas Amabile; Christian Heiss; Wendy May Real; Petros Minasi; Dana McGlothlin; Eduardo J Rame; William Grossman; Teresa De Marco; Yerem Yeghiazarians
Circulating endothelial microparticle levels predict hemodynamic severity of pulmonary hypertension.
American journal of respiratory and critical care medicine 2008;177(11):1268-75.
2008: Christian Heiss; Nicolas Amabile; Andrew C Lee; Wendy May Real; Suzaynn F Schick; David Lao; Maelene L Wong; Sarah Jahn; Franca S Angeli; Petros Minasi; Matthew L Springer; S Katharine Hammond; Stanton A Glantz; William Grossman; John Balmes; Yerem Yeghiazarians
Brief secondhand smoke exposure depresses endothelial progenitor cells activity and endothelial function: sustained vascular injury and blunted nitric oxide production.
Journal of the American College of Cardiology 2008;51(18):1760-71.
2008: Thomas Lauer; Christian Heiss; Jan Balzer; Eva Kehmeier; Sarah Mangold; Thorsten Leyendecker; Jessica Rottler; Christian Meyer; Marc W Merx; Malte Kelm; Tienush Rassaf
Age-dependent endothelial dysfunction is associated with failure to increase plasma nitrite in response to exercise.
Basic research in cardiology 2008;103(3):291-7.
2008: Christian Heiss; Maelene L Wong; Vanessa I Block; David Lao; Wendy May Real; Yerem Yeghiazarians; Randall J Lee; Matthew L Springer
Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells.
Journal of cellular physiology 2008;215(2):366-73.
2008: Christian Heiss; Richard E Sievers; Nicolas Amabile; Tony Y Momma; Qiumei Chen; Shobha Natarajan; Yerem Yeghiazarians; Matthew L Springer
In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound.
American journal of physiology. Heart and circulatory physiology 2008;294(2):H1086-93.
2007: Tienush Rassaf; Thomas Lauer; Christian Heiss; Jan Balzer; Sarah Mangold; Thorsten Leyendecker; Jessica Rottler; Christine Drexhage; Christian Meyer; Malte Kelm
Nitric oxide synthase-derived plasma nitrite predicts exercise capacity.
British journal of sports medicine 2007;41(10):669-73; discussion 673.
2007: Jan Balzer; M Boos; Christian Heiss; Malte Kelm; Simone Matern; Michael Preik; Tienush Rassaf; Frank C Schoebel; Thomas Lauer
"One-stop-shop" ultrasound diagnosis of functional, structural and physicomechanical properties of the brachial artery.
VASA. Zeitschrift für Gefässkrankheiten 2007;36(2):100-6.
2007: Christian Heiss; David Finis; Petra Kleinbongard; Arne Hoffmann; Tienush Rassaf; Malte Kelm; Helmut Sies
Sustained increase in flow-mediated dilation after daily intake of high-flavanol cocoa drink over 1 week.
Journal of cardiovascular pharmacology 2007;49(2):74-80.
2006: Tienush Rassaf; Christian Heiss; Ulrike B Hendgen-Cotta; Jan Balzer; Simone Matern; Petra Kleinbongard; Andrew Lee; Thomas Lauer; Malte Kelm
Plasma nitrite reserve and endothelial function in the human forearm circulation.
Free radical biology & medicine 2006;41(2):295-301.
2006: Christian Heiss; Thomas Lauer; André Dejam; Petra Kleinbongard; Sandra Hamada; Tienush Rassaf; Simone Matern; Martin Feelisch; Malte Kelm
Plasma nitroso compounds are decreased in patients with endothelial dysfunction.
Journal of the American College of Cardiology 2006;47(3):573-9.
2006: Hagen Schroeter; Christian Heiss; Jan Balzer; Petra Kleinbongard; Carl L Keen; Norman K Hollenberg; Helmut Sies; Catherine L Kwik-Uribe; Harold H Schmitz; Malte Kelm
(-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):1024-9.
2006: Christian Heiss; Hagen Schroeter; Jan Balzer; Petra Kleinbongard; Simone Matern; Helmut Sies; Malte Kelm
Endothelial function, nitric oxide, and cocoa flavanols.
Journal of cardiovascular pharmacology 2006;47 Suppl 2():S128-35; discussion S172-6.
2006: Jan Balzer; Christian Heiss; Hagen Schroeter; Paris Brouzos; Petra Kleinbongard; Simone Matern; Thomas Lauer; Tienush Rassaf; Malte Kelm
Flavanols and cardiovascular health: effects on the circulating NO pool in humans.
Journal of cardiovascular pharmacology 2006;47 Suppl 2():S122-7; discussion S172-6.
2005: Christian Heiss; Petra Kleinbongard; André Dejam; Sandra Perré; Hagen Schroeter; Helmut Sies; Malte Kelm
Acute consumption of flavanol-rich cocoa and the reversal of endothelial dysfunction in smokers.
Journal of the American College of Cardiology 2005;46(7):1276-83.
2005: Christian Heiss; Stefanie Keymel; Ulrike Niesler; Jutta Ziemann; Malte Kelm; Christoph Kalka
Impaired progenitor cell activity in age-related endothelial dysfunction.
Journal of the American College of Cardiology 2005;45(9):1441-8.
2005: Thomas Lauer; Christian Heiss; Michael Preik; Jan Balzer; Dieter Hafner; Bodo E Strauer; Malte Kelm
Reduction of peripheral flow reserve impairs endothelial function in conduit arteries of patients with essential hypertension.
Journal of hypertension 2005;23(3):563-9.
2005: Helmut Sies; Tankred Schewe; Christian Heiss; Malte Kelm
Cocoa polyphenols and inflammatory mediators.
The American journal of clinical nutrition 2005;81(1 Suppl):304S-312S.
2003: Christian Heiss; André Dejam; Petra Kleinbongard; Tankred Schewe; Helmut Sies; Malte Kelm
Vascular effects of cocoa rich in flavan-3-ols.
JAMA : the journal of the American Medical Association 2003;290(8):1030-1.
2002: Tienush Rassaf; Michael Preik; Petra Kleinbongard; Thomas Lauer; Christian Heiss; Bodo E Strauer; Martin Feelisch; Malte Kelm
Evidence for in vivo transport of bioactive nitric oxide in human plasma.
The Journal of clinical investigation 2002;109(9):1241-8.
2000: Michael Preik; Thomas Lauer; Christian Heiss; S Tabery; Bodo E Strauer; Malte Kelm
Automated ultrasonic measurement of human arteries for the determination of endothelial function.
Ultraschall in der Medizin (Stuttgart, Germany : 1980) 2000;21(5):195-8.