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Jürgen Herbert Helbig

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Christian Lück; Jürgen Herbert Helbig
Characterization of legionella lipopolysaccharide.
Christian Lück; Norman K Fry; Jürgen Herbert Helbig; Sophie Jarraud; Timothy G Harrison
Typing methods for legionella.
Jürgen Herbert Helbig; Enno Jacobs; Christian Lück
Legionella pneumophila urinary antigen subtyping using monoclonal antibodies as a tool for epidemiological investigations.

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All Publications

2013: Christian Lück; Jürgen Herbert Helbig
Characterization of legionella lipopolysaccharide.
Methods in molecular biology (Clifton, N.J.) 2013;954():381-90.
2013: Christian Lück; Norman K Fry; Jürgen Herbert Helbig; Sophie Jarraud; Timothy G Harrison
Typing methods for legionella.
Methods in molecular biology (Clifton, N.J.) 2013;954():119-48.
2012: Jürgen Herbert Helbig; Enno Jacobs; Christian Lück
Legionella pneumophila urinary antigen subtyping using monoclonal antibodies as a tool for epidemiological investigations.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2012;31(7):1673-7.
2010: Katja Reichardt; Enno Jacobs; Isolde Röske; Jürgen Herbert Helbig
Legionella pneumophila carrying the virulence-associated lipopolysaccharide epitope possesses two functionally different LPS components.
Microbiology (Reading, England) 2010;156(Pt 10):2953-61.
2010: Eva M Seeger; Maria Thuma; Esteban Fernandez-Moreira; Enno Jacobs; Marc Schmitz; Jürgen Herbert Helbig
Lipopolysaccharide of Legionella pneumophila shed in a liquid culture as a nonvesicular fraction arrests phagosome maturation in amoeba and monocytic host cells.
FEMS microbiology letters 2010;307(2):113-9.
2009: Alexander Thürmer; Jürgen Herbert Helbig; Enno Jacobs; Paul Christian Lück
PCR-based 'serotyping' of Legionella pneumophila.
Journal of medical microbiology 2009;58(Pt 5):588-95.
2008: J Borchardt; Jürgen Herbert Helbig; Paul Christian Lück
Occurrence and distribution of sequence types among Legionella pneumophila strains isolated from patients in Germany: common features and differences to other regions of the world.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2008;27(1):29-36.
2007: C Wagner; Claudia Krönert; Paul Christian Lück; Enno Jacobs; N P Cianciotto; Jürgen Herbert Helbig
Random mutagenesis of Legionella pneumophila reveals genes associated with lipopolysaccharide synthesis and recognition by typing monoclonal antibodies.
Journal of applied microbiology 2007;103(5):1975-82.
2007: Sandra Ratzow; Valeria Gaia; Jürgen Herbert Helbig; Norman K Fry; Paul Christian Lück
Addition of neuA, the gene encoding N-acylneuraminate cytidylyl transferase, increases the discriminatory ability of the consensus sequence-based scheme for typing Legionella pneumophila serogroup 1 strains.
Journal of clinical microbiology 2007;45(6):1965-8.
2007: Jürgen Herbert Helbig; R F Benson; C Pelaz; Enno Jacobs; Paul Christian Lück
Identification and serotyping of atypical Legionella pneumophila strains isolated from human and environmental sources.
Journal of applied microbiology 2007;102(1):100-5.
2006: Jürgen Herbert Helbig; Paul Christian Lück; Britta Kunz; Andreas Bubert
Evaluation of the Duopath Legionella lateral flow assay for identification of Legionella pneumophila and Legionella species culture isolates.
Applied and environmental microbiology 2006;72(6):4489-91.
2004: Paul Christian Lück; Liane Igel; Jürgen Herbert Helbig; Eberhard Kuhlisch; Lutz Jatzwauk
Comparison of commercially available media for the recovery of Legionella species.
International journal of hygiene and environmental health 2004;207(6):589-93.
2004: Liane Igel; Jürgen Herbert Helbig; Paul Christian Lück
Isolation and characterization of a nonfluorescent strain of Legionella parisiensis.
Journal of clinical microbiology 2004;42(6):2877-8.
2003: Stefan Monecke; Jürgen Herbert Helbig; Enno Jacobs
Phase variation of the multiple banded protein in Ureaplasma urealyticum and Ureaplasma parvum.
International journal of medical microbiology : IJMM 2003;293(2-3):203-11.
2003: Sverker Bernander; Kerstin Jacobson; Jürgen Herbert Helbig; Paul Christian Lück; Monica Lundholm
A hospital-associated outbreak of Legionnaires' disease caused by Legionella pneumophila serogroup 1 is characterized by stable genetic fingerprinting but variable monoclonal antibody patterns.
Journal of clinical microbiology 2003;41(6):2503-8.
2003: Jürgen Herbert Helbig; Søren A Uldum; Sverker Bernander; Paul Christian Lück; Günther Wewalka; Bill Abraham; Valeria Gaia; Timothy G Harrison
Clinical utility of urinary antigen detection for diagnosis of community-acquired, travel-associated, and nosocomial legionnaires' disease.
Journal of clinical microbiology 2003;41(2):838-40.
2003: Jürgen Herbert Helbig; Bettina König; Henry Knospe; Birgit Bubert; Chao Yu; Christian Lück; Alan Riboldi-Tunnicliffe; Rolf Hilgenfeld; Enno Jacobs; Jörg Hacker; Gunter Fischer
The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells.
Biological chemistry 2003;384(1):125-37.
2002: Jürgen Herbert Helbig; Sverker Bernander; M Castellani Pastoris; Jerome Etienne; Valeria Gaia; Sabine Lauwers; D Lindsay; Paul Christian Lück; T Marques; S Mentula; M F Peeters; C Pelaz; Marc Struelens; Søren A Uldum; Günther Wewalka; Timothy G Harrison
Pan-European study on culture-proven Legionnaires' disease: distribution of Legionella pneumophila serogroups and monoclonal subgroups.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2002;21(10):710-6.
2001: K Röske; Alain Blanchard; Isabelle Chambaud; Christine Citti; Jürgen Herbert Helbig; Marie-Christine Prevost; Renate Rosengarten; Enno Jacobs
Phase variation among major surface antigens of Mycoplasma penetrans.
Infection and immunity 2001;69(12):7642-51.
2001: Paul Christian Lück; T Freier; C Steudel; Y A Knirel; E Lüneberg; U Zähringer; Jürgen Herbert Helbig
A point mutation in the active site of Legionella pneumophila O-acetyltransferase results in modified lipopolysaccharide but does not influence virulence.
International journal of medical microbiology : IJMM 2001;291(5):345-52.
2001: Michael Steinert; M Flügel; M Schuppler; Jürgen Herbert Helbig; Agus Supriyono; Peter Proksch; Paul Christian Lück
The Lly protein is essential for p-hydroxyphenylpyruvate dioxygenase activity in Legionella pneumophila.
FEMS microbiology letters 2001;203(1):41-7.
2001: Jürgen Herbert Helbig; Søren A Uldum; Paul Christian Lück; Timothy G Harrison
Detection of Legionella pneumophila antigen in urine samples by the BinaxNOW immunochromatographic assay and comparison with both Binax Legionella Urinary Enzyme Immunoassay (EIA) and Biotest Legionella Urin Antigen EIA.
Journal of medical microbiology 2001;50(6):509-16.
2001: Jürgen Herbert Helbig; Paul Christian Lück; Michael Steinert; Enno Jacobs; M Witt
Immunolocalization of the Mip protein of intracellularly and extracellularly grown Legionella pneumophila.
Letters in applied microbiology 2001;32(2):83-8.
2000: Konrad Sachse; Jürgen Herbert Helbig; Inna Lysnyansky; C Grajetzki; W Müller; Enno Jacobs; David Yogev
Epitope mapping of immunogenic and adhesive structures in repetitive domains of Mycoplasma bovis variable surface lipoproteins.
Infection and immunity 2000;68(2):680-7.
1999: Jürgen Herbert Helbig; T Engelstädter; Matthias Maiwald; Søren A Uldum; Wolf-Christoph Witzleb; Paul Christian Lück
Diagnostic relevance of the detection of Legionella DNA in urine samples by the polymerase chain reaction.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1999;18(10):716-22.
1999: Paolo Visca; Paola Goldoni; Paul Christian Lück; Jürgen Herbert Helbig; L Cattani; G Giltri; S Bramati; M Castellani Pastoris
Multiple types of Legionella pneumophila serogroup 6 in a hospital heated-water system associated with sporadic infections.
Journal of clinical microbiology 1999;37(7):2189-96.
1999: J R Köhler; Matthias Maiwald; Paul Christian Lück; Jürgen Herbert Helbig; V Hingst; Hans-Günther Sonntag
Detecting legionellosis by unselected culture of respiratory tract secretions and developing links to hospital water strains.
The Journal of hospital infection 1999;41(4):301-11.
1998: Paul Christian Lück; J W Schmitt; A Hengerer; Jürgen Herbert Helbig
Subinhibitory concentrations of antimicrobial agents reduce the uptake of Legionella pneumophila into Acanthamoeba castellanii and U937 cells by altering the expression of virulence-associated antigens.
Antimicrobial agents and chemotherapy 1998;42(11):2870-6.
1998: Paul Christian Lück; H M Wenchel; Jürgen Herbert Helbig
Nosocomial pneumonia caused by three genetically different strains of Legionella pneumophila and detection of these strains in the hospital water supply.
Journal of clinical microbiology 1998;36(4):1160-3.
1997: Jürgen Herbert Helbig; J B Kurtz; M C Pastoris; C Pelaz; Paul Christian Lück
Antigenic lipopolysaccharide components of Legionella pneumophila recognized by monoclonal antibodies: possibilities and limitations for division of the species into serogroups.
Journal of clinical microbiology 1997;35(11):2841-5.
1995: Jürgen Herbert Helbig; Paul Christian Lück; Y A Knirel; W Witzleb; U Zähringer
Molecular characterization of a virulence-associated epitope on the lipopolysaccharide of Legionella pneumophila serogroup 1.
Epidemiology and infection 1995;115(1):71-8.
1995: Paul Christian Lück; Jürgen Herbert Helbig; H J Hagedorn; W Ehret
DNA fingerprinting by pulsed-field gel electrophoresis to investigate a nosocomial pneumonia caused by Legionella bozemanii serogroup 1.
Applied and environmental microbiology 1995;61(7):2759-61.
1995: Paul Christian Lück; R J Birtles; Jürgen Herbert Helbig
Correlation of MAb subgroups with genotype in closely related Legionella pneumophila serogroup 1 strains from a cooling tower.
Journal of medical microbiology 1995;43(1):50-4.
1995: Paul Christian Lück; J Köhler; Matthias Maiwald; Jürgen Herbert Helbig
DNA polymorphisms in strains of Legionella pneumophila serogroups 3 and 4 detected by macrorestriction analysis and their use for epidemiological investigation of nosocomial legionellosis.
Applied and environmental microbiology 1995;61(5):2000-3.
1995: Jürgen Herbert Helbig; B Ludwig; Paul Christian Lück; A Groh; W Witzleb; J Hacker
Monoclonal antibodies to Legionella Mip proteins recognize genus- and species-specific epitopes.
Clinical and diagnostic laboratory immunology 1995;2(2):160-5.
1995: Paul Christian Lück; Jürgen Herbert Helbig; V Drasar; N Bornstein; R J Fallon; M Castellani Pastoris
Genomic heterogenicity amongst phenotypically similar Legionella micdadei strains.
FEMS microbiology letters 1995;126(1):49-54.
1995: Paul Christian Lück; Jürgen Herbert Helbig
[Molecular typing of Legionella for determining the source of infection].
Immunität und Infektion 1995;23(1):15-8.
1995: Paul Christian Lück; Jürgen Herbert Helbig; W Ehret; M Ott
Isolation of a Legionella pneumophila strain serologically distinguishable from all known serogroups.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1995;282(1):35-9.
1995: Matthias Maiwald; M Schill; C Stockinger; Jürgen Herbert Helbig; Paul Christian Lück; W Witzleb; H G Sonntag
Detection of Legionella DNA in human and guinea pig urine samples by the polymerase chain reaction.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1995;14(1):25-33.
1994: Paul Christian Lück; Jürgen Herbert Helbig; U Günter; M Assmann; R Blau; H Koch; M Klepp
Epidemiologic investigation by macrorestriction analysis and by using monoclonal antibodies of nosocomial pneumonia caused by Legionella pneumophila serogroup 10.
Journal of clinical microbiology 1994;32(11):2692-7.
1994: Paul Christian Lück; E Dinger; Jürgen Herbert Helbig; V Thurm; H Keuchel; C Presch; M Ott
Analysis of Legionella pneumophila strains associated with nosocomial pneumonia in a neonatal intensive care unit.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1994;13(7):565-71.
1994: Paul Christian Lück; G Lobeck; G Stenzel; C Conzendorf; Jürgen Herbert Helbig
[Legionella pneumonia after travel to Mediterranean countries].
Zeitschrift für ärztliche Fortbildung 1994;88(5-6):433-6.
1994: Jürgen Herbert Helbig; Paul Christian Lück; W Witzleb
Serogroup-specific and serogroup-cross-reactive epitopes of Legionella pneumophila.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1994;281(1):16-23.
1993: Jürgen Herbert Helbig; Paul Christian Lück; K Röske; W Witzleb
[Detection of intracellular multiplication of Legionella pneumophila in protozoa by antigen quantification using ELISA].
Zentralblatt für Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine 1993;194(4):392-7.
1993: Paul Christian Lück; I Leupold; Matthias Hlawitschka; Jürgen Herbert Helbig; I Carmienke; L Jatzwauk; T Guderitz
Prevalence of Legionella species, serogroups, and monoclonal subgroups in hot water systems in south-eastern Germany.
Zentralblatt für Hygiene und Umweltmedizin = International journal of hygiene and environmental medicine 1993;193(5):450-60.
1993: Paul Christian Lück; Jürgen Herbert Helbig
[Epidemiology of legionellosis].
Schriftenreihe des Vereins für Wasser-, Boden- und Lufthygiene 1993;91():41-58.
1992: Paul Christian Lück; Jürgen Herbert Helbig; W Ehret; R Marre; W Witzleb
Subtyping of Legionella pneumophila serogroup 1 strains isolated in Germany using monoclonal antibodies.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1992;277(2):179-87.
1992: Paul Christian Lück; R Rasch; C Schmidt; Jürgen Herbert Helbig; W Ehret; B Stockmann; W Witzleb
[A minor epidemic due to Legionella pneumophila serogroup 1].
Deutsche medizinische Wochenschrift (1946) 1992;117(12):460-4.
1991: Paul Christian Lück; L Bender; M Ott; Jürgen Herbert Helbig; Jörg Hacker
Analysis of Legionella pneumophila serogroup 6 strains isolated from a hospital warm water supply over a three-year period by using genomic long-range mapping techniques and monoclonal antibodies.
Applied and environmental microbiology 1991;57(11):3226-31.
1991: Jürgen Herbert Helbig; Paul Christian Lück; C Pilz; W Witzleb
[Determination of Legionella antigens using monoclonal antibodies].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1991;37(2):87-9.
1991: Paul Christian Lück; Jürgen Herbert Helbig; C Pilz; W Witzleb
Monoclonal antibodies to Legionella pneumophila serogroup 6: evidence of antigenic diversity.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1991;274(4):533-6.
1990: Jürgen Herbert Helbig; Paul Christian Lück; C Pilz; W Witzleb
Common epitope on urinary antigen derived from different Legionella pneumophila serogroup 1 strains recognized by a monoclonal antibody.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1990;273(4):478-80.
1990: Paul Christian Lück; Jürgen Herbert Helbig; W Witzleb
[Legionella in water of medical facilities--a hazard for patients and personnel?].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1990;36(7):380-2.
1990: Paul Christian Lück; Jürgen Herbert Helbig; W Witzleb
[Culture and biochemical differentiation of Legionella at the microbiologic laboratory].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1990;36(2):114-7.
1989: Paul Christian Lück; Jürgen Herbert Helbig; E Wunderlich; H Foelske; M Selbitschka; D Wenzel; L Pätzold; W Witzleb
Isolation of Legionella pneumophila serogroup 3 from pericardial fluid in a case of pericarditis.
Infection 1989;17(6):388-90.
1989: Paul Christian Lück; Jürgen Herbert Helbig; C Pilz; W Witzleb
[Detection of legionellas in clinical samples using FITC-marked antibodies].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1989;35(10):601-4.
1989: Jürgen Herbert Helbig; R Blaschke-Hellmessen; Paul Christian Lück
[Determination of Candida albicans mannan antigen in serum].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1989;35(10):599-600.
1989: Jürgen Herbert Helbig; Paul Christian Lück; W Witzleb
[Diagnosis of Legionella pneumonia by detection of antigenuria using an enzyme immunoassay with 6 antibody specificities].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1989;35(10):591-3.
1989: Paul Christian Lück; Jürgen Herbert Helbig; W Witzleb
Immunofluorescent staining of influenza virus antigen in fixed and paraffin-embedded tissue of experimentally infected hamsters.
Acta histochemica 1989;85(1):47-50.
1986: Jürgen Herbert Helbig; K Muschner; E Füssel; W Witzleb
[Determination of the influenza A virus antigen in pharyngeal swabs using an enzyme immunoassay].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1986;32(10):615-7.
1986: W Witzleb; Jürgen Herbert Helbig
[Experimental studies on Mycoplasma pneumoniae antigen detection by enzyme-linked immunosorbent assay (ELISA)].
Archiv für experimentelle Veterinärmedizin 1986;40(1):109-14.
1986: Paul Christian Lück; Jürgen Herbert Helbig
[Quantitative determination of syphilis-specific antibodies with the 19S IgM FTA-ABS test].
Dermatologische Monatschrift 1986;172(2):73-6.
1985: Jürgen Herbert Helbig; R Blaschke-Hellmessen
[Detection of antibodies to Aspergillus fumigatus using enzyme immunoassay and counterimmunoelectrophoresis].
Zeitschrift für medizinische Laboratoriumsdiagnostik 1985;26(6):331-6.
1985: G Thess; E Budde; Jürgen Herbert Helbig; K Muschner; W Witzleb
[Direct detection of influenza virus A in animal study material with the enzyme-linked immunosorbent assay (ELISA)].
Zeitschrift für medizinische Laboratoriumsdiagnostik 1985;26(1):39-43.
1984: Jürgen Herbert Helbig; W Witzleb
[Enzyme-linked immunosorbent assay (ELISA) for the detection of Mycoplasma pneumoniae antigens].
Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete 1984;30(2):106-7.