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Hitoshi Ashida

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Yoko Yamashita; Hitoshi Ashida; Tomohisa Hasunuma; Masaru Yamaoka; Ken-Ichi Yoshida
Detection of orally administered inositol stereoisomers in mouse blood plasma and their effects on translocation of glucose transporter 4 in skeletal muscle cells.
Yoko Yamashita; Midori Natsume; Masaaki Okabe; Hitoshi Ashida
Cinnamtannin A2, a Tetrameric Procyanidin, Increases GLP-1 and Insulin Secretion in Mice.
Tianshun Zhang; Chao He; Songyan Jiang; Yuki Kimura; Yoko Yamashita; Hitoshi Ashida
Black soybean seed coat polyphenols prevent B(a)P-induced DNA damage through modulating drug-metabolizing enzymes in HepG2 cells and ICR mice.

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2013: Yoko Yamashita; Hitoshi Ashida; Tomohisa Hasunuma; Masaru Yamaoka; Ken-Ichi Yoshida
Detection of orally administered inositol stereoisomers in mouse blood plasma and their effects on translocation of glucose transporter 4 in skeletal muscle cells.
Journal of agricultural and food chemistry 2013;61(20):4850-4.
2013: Yoko Yamashita; Midori Natsume; Masaaki Okabe; Hitoshi Ashida
Cinnamtannin A2, a Tetrameric Procyanidin, Increases GLP-1 and Insulin Secretion in Mice.
Bioscience, biotechnology, and biochemistry 2013;77(4):888-91.
2013: Tianshun Zhang; Chao He; Songyan Jiang; Yuki Kimura; Yoko Yamashita; Hitoshi Ashida
Black soybean seed coat polyphenols prevent B(a)P-induced DNA damage through modulating drug-metabolizing enzymes in HepG2 cells and ICR mice.
Mutation research 2013;752(1-2):34-41.
2012: Yoko Yamashita; Midori Natsume; Masaaki Okabe; Hitoshi Ashida
Prevention mechanisms of glucose intolerance and obesity by cacao liquor procyanidin extract in high-fat diet-fed C57BL/6 mice.
Archives of biochemistry and biophysics 2012;527(2):95-104.
2012: Yoko Yamashita; Toshiyuki Nakamura; Zhang Tinshun; Lihua Wang; Hitoshi Ashida
Fermented tea improves glucose intolerance in mice by enhancing translocation of glucose transporter 4 in skeletal muscle.
Journal of agricultural and food chemistry 2012;60(45):11366-71.
2012: Shin Nishiumi; Takashi Ichiyanagi; Rie Mukai; Hitoshi Ashida
Suppression of lipopolysaccharide and galactosamine-induced hepatic inflammation by red grape pomace.
Journal of agricultural and food chemistry 2012;60(36):9315-20.
2012: Manabu Ueda; Hitoshi Ashida
Green tea prevents obesity by increasing expression of insulin-like growth factor binding protein-1 in adipose tissue of high-fat diet-fed mice.
Journal of agricultural and food chemistry 2012;60(36):8917-23.
2012: Toshiyuki Nakamura; Takahiro Tokushima; Norio Yamamoto; Kyuichi Kawabata; Masaaki Miyamoto; Hitoshi Ashida
Absorption and metabolism of 4-hydroxyderricin and xanthoangelol after oral administration of Angelica keiskei (Ashitaba) extract in mice.
Archives of biochemistry and biophysics 2012;521(1-2):71-6.
2012: Shin Nishiumi; Toshiro Shibata; Ken-ichi Yoshida; Masaki Anetai; Keizo Hosokawa; Rie Mukai; Hitoshi Ashida
Antagonistic effect of the Ainu-selected traditional beneficial plants on the transformation of an aryl hydrocarbon receptor.
Journal of food science 2012;77(4):C420-9.
2012: Sachiko Nakamura-Tsuruta; Eri Shinoda; Hiroki Takata; Michiko Yasuda; Takashi Furuyashiki; Ryo Kakutani; Yoji Kato; Toshiyuki Nakamura; Hitoshi Ashida
Comparative analysis of carbohydrate-binding specificities of two anti-glycogen monoclonal antibodies using ELISA and surface plasmon resonance.
Carbohydrate research 2012;350():49-54.
2012: Sayuri Shimazu; Hideo Ohkawa; Masaya Ohta; Hitoshi Ashida
Assays of polychlorinated biphenyl congeners and co-contaminated heavy metals in the transgenic Arabidopsis plants carrying the recombinant guinea pig aryl hydrocarbon receptor-mediated β-glucuronidase reporter gene expression system.
Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 2012;47(10):925-32.
2012: Keisuke Sawada; Norio Yamamoto; Takatoshi Yamashita; Kyuichi Kawabata; Kengo Kawasaki; Hitoshi Ashida
Ameliorative effects of polyunsaturated fatty acids against palmitic acid-induced insulin resistance in L6 skeletal muscle cells.
Lipids in health and disease 2012;11():36.
2011: Itsuko Fukuda; Toshiya Toda; Takanori Tsuda; Miki Tsutsui; Tadashi Yoshida; Hitoshi Ashida
Oral toxicological studies of black soybean (Glycine max) hull extract: acute studies in rats and mice, and chronic studies in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2011;49(12):3272-8.
2011: Keisuke Furumatsu; Yuki Kawano; Hiromu Kutsumi; Shin Nishiumi; Makoto Ooi; Yuuki Shiomi; Hitoshi Ashida; Takeshi Azuma; Yoshiaki Fujii-Kuriyama; Tomoo Yoshie; Masaru Yoshida
A role of the aryl hydrocarbon receptor in attenuation of colitis.
Digestive diseases and sciences 2011;56(9):2532-44.
2011: Yuki Kanamoto; Sachiko Nakamura-Tsuruta; Fumio Nanba; Takanori Tsuda; Yoko Yamashita; Tadashi Yoshida; Itsuko Fukuda; Hitoshi Ashida
A black soybean seed coat extract prevents obesity and glucose intolerance by up-regulating uncoupling proteins and down-regulating inflammatory cytokines in high-fat diet-fed mice.
Journal of agricultural and food chemistry 2011;59(16):8985-93.
2011: Takashi Furuyashiki; Iwao Kojima; Takashi Kuriki; Hiroki Takata; Itsuko Fukuda; Hitoshi Ashida
Metabolic fate of orally administered enzymatically synthesized glycogen in rats.
Food & function 2011;2(3-4):183-9.
2011: Kyuichi Kawabata; Keisuke Sawada; Kazunori Ikeda; Itsuko Fukuda; Kengo Kawasaki; Norio Yamamoto; Hitoshi Ashida
Prenylated chalcones 4-hydroxyderricin and xanthoangelol stimulate glucose uptake in skeletal muscle cells by inducing GLUT4 translocation.
Molecular nutrition & food research 2011;55(3):467-75.
2011: Toshiyuki Nakamura; Ryohei Tanaka; Hitoshi Ashida
Possible evidence of contamination by catechins in deconjugation enzymes from Helix pomatia and Abalone entrails.
Bioscience, biotechnology, and biochemistry 2011;75(8):1506-10.
2011: Shin Nishiumi; Shingo Miyamoto; Kyuichi Kawabata; Kohta Ohnishi; Rie Mukai; Akira Murakami; Hitoshi Ashida; Junji Terao
Dietary flavonoids as cancer-preventive and therapeutic biofactors.
Frontiers in bioscience (Scholar edition) 2011;3():1332-62.
2010: Shin Nishiumi; Hiroaki Bessyo; Mayuko Kubo; Yukiko Aoki; Akihito Tanaka; Ken-ichi Yoshida; Hitoshi Ashida
Green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed C57BL/6J mice.
Journal of agricultural and food chemistry 2010;58(24):12916-23.
2010: Yuki Kawano; Shin Nishiumi; Shinwa Tanaka; Kentaro Nobutani; Akira Miki; Yoshihiko Yano; Yasushi Seo; Hiromu Kutsumi; Hitoshi Ashida; Takeshi Azuma; Masaru Yoshida
Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport.
Archives of biochemistry and biophysics 2010;504(2):221-7.
2010: Manabu Ueda; Kayo Yamada; Ken-Ichi Yoshida; Yukiko Aoki; Itsuko Fukuda; Takashi Furuyashiki; Iwao Sakane; Hitoshi Ashida
Tea catechins modulate the glucose transport system in 3T3-L1 adipocytes.
Food & function 2010;1(2):167-73.
2010: Rie Mukai; Yasuhito Shirai; Naoaki Saito; Itsuko Fukuda; Shin Nishiumi; Ken-Ichi Yoshida; Hitoshi Ashida
Suppression mechanisms of flavonoids on aryl hydrocarbon receptor-mediated signal transduction.
Archives of biochemistry and biophysics 2010;501(1):134-41.
2010: Tetsuro Morinaga; Kazuo Kobayashi; Hitoshi Ashida; Yasutaro Fujita; Ken-Ichi Yoshida
Transcriptional regulation of the Bacillus subtilis asnH operon and role of the 5'-proximal long sequence triplication in RNA stabilization.
Microbiology (Reading, England) 2010;156(Pt 6):1632-41.
2010: Shin Nishiumi; Masaru Yoshida; Takeshi Azuma; Ken-Ichi Yoshida; Hitoshi Ashida
2,3,7,8-tetrachlorodibenzo-p-dioxin impairs an insulin signaling pathway through the induction of tumor necrosis factor-alpha in adipocytes.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(2):482-91.
2010: Tetsuro Morinaga; Hitoshi Ashida; Ken-ichi Yoshida
Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.
Microbiology (Reading, England) 2010;156(Pt 5):1538-46.
2010: Tetsuro Morinaga; Takatsugu Matsuse; Hitoshi Ashida; Ken-Ichi Yoshida
Differential substrate specificity of two inositol transporters of Bacillus subtilis.
Bioscience, biotechnology, and biochemistry 2010;74(6):1312-4.
2010: Nhung Thuy Dang; Rie Mukai; Ken-Ichi Yoshida; Hitoshi Ashida
D-pinitol and myo-inositol stimulate translocation of glucose transporter 4 in skeletal muscle of C57BL/6 mice.
Bioscience, biotechnology, and biochemistry 2010;74(5):1062-7.
2009: Masaki Kinehara; Itsuko Fukuda; Ken-ichi Yoshida; Hitoshi Ashida
Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A(2)alpha gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells.
Journal of bioscience and bioengineering 2009;108(4):277-81.
2009: Rie Mukai; Hideo Satsu; Makoto Shimizu; Hitoshi Ashida
Inhibition of P-glycoprotein enhances the suppressive effect of kaempferol on transformation of the aryl hydrocarbon receptor.
Bioscience, biotechnology, and biochemistry 2009;73(7):1635-9.
2009: Itsuko Fukuda; Miki Tsutsui; Iwao Sakane; Hitoshi Ashida
Suppression of cytochrome P450 1A1 expression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma hepa-1c1c7 cells treated with serum of (-)-epigallocatechin-3-gallate- and green tea extract-administered rats.
Bioscience, biotechnology, and biochemistry 2009;73(5):1206-8.
2009: Rie Mukai; Yasuhito Shirai; Naoaki Saito; Ken-Ichi Yoshida; Hitoshi Ashida
Subcellular localization of flavonol aglycone in hepatocytes visualized by confocal laser scanning fluorescence microscope.
Cytotechnology 2009;59(3):177-82.
2009: Itsuko Fukuda; Atsushi Kaneko; Shin Nishiumi; Masaya Kawase; Rika Nishikiori; Nobuhide Fujitake; Hitoshi Ashida
Structure-activity relationships of anthraquinones on the suppression of DNA-binding activity of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Journal of bioscience and bioengineering 2009;107(3):296-300.
2008: Manabu Ueda; Shin Nishiumi; Hironobu Nagayasu; Itsuko Fukuda; Ken-ichi Yoshida; Hitoshi Ashida
Epigallocatechin gallate promotes GLUT4 translocation in skeletal muscle.
Biochemical and biophysical research communications 2008;377(1):286-90.
2008: Masaki Kinehara; Itsuko Fukuda; Ken-Ichi Yoshida; Hitoshi Ashida
High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Genes & genetic systems 2008;83(6):455-68.
2008: Rie Mukai; Itsuko Fukuda; Shin Nishiumi; Midori Natsume; Naomi Osakabe; Ken-ichi Yoshida; Hitoshi Ashida
Cacao polyphenol extract suppresses transformation of an aryl hydrocarbon receptor in C57BL/6 mice.
Journal of agricultural and food chemistry 2008;56(21):10399-405.
2008: Hitoshi Ashida; Shin Nishiumi; Itsuko Fukuda
An update on the dietary ligands of the AhR.
Expert opinion on drug metabolism & toxicology 2008;4(11):1429-47.
2008: Shin Nishiumi; Yoshiyuki Yabushita; Takashi Furuyashiki; Itsuko Fukuda; Hitoshi Ashida
Involvement of SREBPs in 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced disruption of lipid metabolism in male guinea pig.
Toxicology and applied pharmacology 2008;229(3):281-9.
2008: Ken-ichi Yoshida; Masanori Yamaguchi; Tetsuro Morinaga; Masaki Kinehara; Maya Ikeuchi; Hitoshi Ashida; Yasutaro Fujita
myo-Inositol catabolism in Bacillus subtilis.
The Journal of biological chemistry 2008;283(16):10415-24.
2008: Shin Nishiumi; Norio Yamamoto; Rie Kodoi; Itsuko Fukuda; Ken-ichi Yoshida; Hitoshi Ashida
Antagonistic and agonistic effects of indigoids on the transformation of an aryl hydrocarbon receptor.
Archives of biochemistry and biophysics 2008;470(2):187-99.
2008: Hideo Nakabayashi; Takashi Hashimoto; Hitoshi Ashida; Shin Nishiumi; Kazuki Kanazawa
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
BioFactors (Oxford, England) 2008;34(4):293-302.
2007: Angeline Yap; Shin Nishiumi; Ken-Ichi Yoshida; Hitoshi Ashida
Rat L6 myotubes as an in vitro model system to study GLUT4-dependent glucose uptake stimulated by inositol derivatives.
Cytotechnology 2007;55(2-3):103-8.
2007: Shin Nishiumi; Ken-Ichi Yoshida; Hitoshi Ashida
Curcumin suppresses the transformation of an aryl hydrocarbon receptor through its phosphorylation.
Archives of biochemistry and biophysics 2007;466(2):267-73.
2007: Shin Nishiumi; Hitoshi Ashida
Rapid preparation of a plasma membrane fraction from adipocytes and muscle cells: application to detection of translocated glucose transporter 4 on the plasma membrane.
Bioscience, biotechnology, and biochemistry 2007;71(9):2343-6.
2007: Itsuko Fukuda; Rie Mukai; Masaya Kawase; Ken-ichi Yoshida; Hitoshi Ashida
Interaction between the aryl hydrocarbon receptor and its antagonists, flavonoids.
Biochemical and biophysical research communications 2007;359(3):822-7.
2006: Ken-Ichi Yoshida; Won-Seok Kim; Masaki Kinehara; Rie Mukai; Hitoshi Ashida; Hideki Ikeda; Yasutaro Fujita; Hari B Krishnan
Identification of a functional 2-keto-myo-inositol dehydratase gene of Sinorhizobium fredii USDA191 required for myo-inositol utilization.
Bioscience, biotechnology, and biochemistry 2006;70(12):2957-64.
2006: Tetsuro Morinaga; Masanori Yamaguchi; Yuki Makino; Hideaki Nanamiya; Kiwamu Takahashi; Hirofumi Yoshikawa; Fujio Kawamura; Hitoshi Ashida; Ken-Ichi Yoshida
Functional myo-inositol catabolic genes of Bacillus subtilis Natto are involved in depletion of pinitol in Natto (fermented soybean).
Bioscience, biotechnology, and biochemistry 2006;70(8):1913-20.
2006: Shin Nishiumi; Keizo Hosokawa; Rie Mukai; Itsuko Fukuda; Atsuyuki Hishida; Osamu Iida; Ken-ichi Yoshida; Hitoshi Ashida
Screening of indigenous plants from Japan for modulating effects on transformation of the aryl hydrocarbon receptor.
Asian Pacific journal of cancer prevention : APJCP 2006;7(2):208-20.
2006: Ken-ichi Yoshida; Masanori Yamaguchi; Tetsuro Morinaga; Maya Ikeuchi; Masaki Kinehara; Hitoshi Ashida
Genetic modification of Bacillus subtilis for production of D-chiro-inositol, an investigational drug candidate for treatment of type 2 diabetes and polycystic ovary syndrome.
Applied and environmental microbiology 2006;72(2):1310-5.
2006: Shin Nishiumi; Yoshiyuki Yabushita; Itsuko Fukuda; Rie Mukai; Ken-Ichi Yoshida; Hitoshi Ashida
Molokhia (Corchorus olitorius L.) extract suppresses transformation of the aryl hydrocarbon receptor induced by dioxins.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(2):250-60.
2006: Takashi Hashimoto; Yuko Ueda; Naomi Oi; Hiroyuki Sakakibara; Chengyuan Piao; Hitoshi Ashida; Miho Goto; Kazuki Kanazawa
Effects of combined administration of quercetin, rutin, and extract of white radish sprout rich in kaempferol glycosides on the metabolism in rats.
Bioscience, biotechnology, and biochemistry 2006;70(1):279-81.
2005: Rie Mukai; Itsuko Fukuda; Keizo Hosokawa; Shin Nishiumi; Atsushi Kaneko; Hitoshi Ashida
Anthocyans fail to suppress transformation of aryl hydrocarbon receptor induced by dioxin.
Bioscience, biotechnology, and biochemistry 2005;69(5):896-903.
2005: Itsuko Fukuda; Iwao Sakane; Yoshiyuki Yabushita; Shin-ichi Sawamura; Kazuki Kanazawa; Hitoshi Ashida
Black tea theaflavins suppress dioxin-induced transformation of the aryl hydrocarbon receptor.
Bioscience, biotechnology, and biochemistry 2005;69(5):883-90.
2004: Takashi Furuyashiki; Hironobu Nagayasu; Yukiko Aoki; Hiroaki Bessho; Takashi Hashimoto; Kazuki Kanazawa; Hitoshi Ashida
Tea catechin suppresses adipocyte differentiation accompanied by down-regulation of PPARgamma2 and C/EBPalpha in 3T3-L1 cells.
Bioscience, biotechnology, and biochemistry 2004;68(11):2353-9.
2004: Bunsyo Shiotani; Hitoshi Ashida
3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) triggers apoptosis by DNA double-strand breaks caused by inhibition of topoisomerase I.
Carcinogenesis 2004;25(7):1149-55.
2004: Itsuko Fukuda; Iwao Sakane; Yoshiyuki Yabushita; Rie Kodoi; Shin Nishiumi; Takami Kakuda; Shin-ichi Sawamura; Kazuki Kanazawa; Hitoshi Ashida
Pigments in green tea leaves (Camellia sinensis) suppress transformation of the aryl hydrocarbon receptor induced by dioxin.
Journal of agricultural and food chemistry 2004;52(9):2499-506.
2004: Kazuo Shimizu; Hitoshi Ashida; Yukinaga Matsuura; Kazuki Kanazawa
Antioxidative bioavailability of artepillin C in Brazilian propolis.
Archives of biochemistry and biophysics 2004;424(2):181-8.
2004: Takashi Hashimoto; Takashi Sano; Wakana Ito; Kazuki Kanazawa; Gen-ichi Danno; Hitoshi Ashida
3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole induces apoptosis and necrosis with activation of different caspases in rat splenocytes.
Bioscience, biotechnology, and biochemistry 2004;68(4):964-7.
2004: Itsuko Fukuda; Shin Nishiumi; Yoshiyuki Yabushita; Rie Mukai; Rie Kodoi; Kaoru Hashizume; Masashi Mizuno; Yutaka Hatanaka; Hitoshi Ashida
A new southwestern chemistry-based ELISA for detection of aryl hydrocarbon receptor transformation: application to the screening of its receptor agonists and antagonists.
Journal of immunological methods 2004;287(1-2):187-201.
2004: Hitoshi Ashida; Takashi Furuyashiki; Hironobu Nagayasu; Hiroaki Bessho; Hiroyuki Sakakibara; Takashi Hashimoto; Kazuki Kanazawa
Anti-obesity actions of green tea: possible involvements in modulation of the glucose uptake system and suppression of the adipogenesis-related transcription factors.
BioFactors (Oxford, England) 2004;22(1-4):135-40.
2004: Takashi Okamoto; Rie Kodoi; Yuji Nonaka; Itsuko Fukuda; Takashi Hashimoto; Kazuki Kanazawa; Masashi Mizuno; Hitoshi Ashida
Lentinan from shiitake mushroom (Lentinus edodes) suppresses expression of cytochrome P450 1A subfamily in the mouse liver.
BioFactors (Oxford, England) 2004;21(1-4):407-9.
2004: Rie Mukai; Itsuko Fukuda; Shin Nishiumi; Keizo Hosokawa; Kazuki Kanazawa; Hitoshi Ashida
Anthocyan does not suppress transformation of aryl hydrocarbon receptor induced by dioxin.
BioFactors (Oxford, England) 2004;21(1-4):371-3.
2004: Itsuko Fukuda; Iwao Sakane; Yoshiyuki Yabushita; Shin-ichi Sawamura; Kazuki Kanazawa; Hitoshi Ashida
Black tea extract suppresses transformation of aryl hydrocarbon receptor induced by dioxin.
BioFactors (Oxford, England) 2004;21(1-4):367-9.
2003: Hiroyuki Sakakibara; Yoshinori Honda; Satoshi Nakagawa; Hitoshi Ashida; Kazuki Kanazawa
Simultaneous determination of all polyphenols in vegetables, fruits, and teas.
Journal of agricultural and food chemistry 2003;51(3):571-81.
2002: Yutaka Hatanaka; Hitoshi Ashida; Kaoru Hashizume; Itsuko Fukuda; Takashi Sano; Yukihiro Yamaguchi; Takeshi Endo; Yoichi Tani; Keiichiro Suzukia; Gen-ichi Danno
Up-regulation of CD13/aminopeptidase N induced by phorbol ester is involved in redox regulation and tumor necrosis factor alpha production in HL-60 cells.
Inflammation 2002;26(4):175-81.
2002: Takashi Hashimoto; Yuji Nonaka; Ken-ichiro Minato; Sachiko Kawakami; Masashi Mizuno; Itsuko Fukuda; Kazuki Kanazawa; Hitoshi Ashida
Suppressive effect of polysaccharides from the edible and medicinal mushrooms, Lentinus edodes and Agaricus blazei, on the expression of cytochrome P450s in mice.
Bioscience, biotechnology, and biochemistry 2002;66(7):1610-4.
2002: Takashi Hashimoto; Takashi Furuyashiki; Takashi Sano; Wakana Ito; Gen-ichi Danno; Kazuki Kanazawa; Hitoshi Ashida
3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (trp-P-1) is incorporated into rat splenocytes, thymocytes, and hepatocytes through monoamine transporters and induces apoptosis.
Bioscience, biotechnology, and biochemistry 2002;66(6):1205-12.
2002: Hidetoshi Arima; Hitoshi Ashida; Gen-ichi Danno
Rutin-enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteritidis.
Bioscience, biotechnology, and biochemistry 2002;66(5):1009-14.
2002: Reiko Nakai; Hitoshi Ashida; Gen-ichi Danno
Effect of different heating conditions on the extractability of barley hordeins.
Journal of nutritional science and vitaminology 2002;48(2):149-54.
2002: Hiroyuki Sakakibara; Hitoshi Ashida; Kazuki Kanazawa
A novel method using 8-hydroperoxy-2'-deoxyguanosine formation for evaluating antioxidative potency.
Free radical research 2002;36(3):307-16.
2002: Mingzhou Sun; Ryo Yamauchi; Hitoshi Ashida; Kazuki Kanazawa
Subsequent products after antioxidant actions of beta-carotene and alpha-tocopherol have no Salmonella mutagenicity.
Bioscience, biotechnology, and biochemistry 2002;66(2):363-72.
2002: Bunsyo Shiotani; Yuji Nonaka; Kazuki Kanazawa; Gen-ichi Danno; Hitoshi Ashida
Evoking cytochrome P450 1A activity interferes with apoptosis induced by 3-amino-1,4-dimethyl-5H-pyrido [4,3-b]indole (Trp-P-1) in rat hepatocytes under the ex vivo system.
Bioscience, biotechnology, and biochemistry 2002;66(2):356-62.
2002: Takashi Hashimoto; Takashi Furuyashiki; Takashi Sano; Kaori Kihara; Itsuko Fukuda; Wakana Ito; Pyoyun Park; Kazuki Kanazawa; Gen-ichi Danno; Hitoshi Ashida
Apoptosis in the thymus after intraperitoneal injection of rats with Trp-P-1.
Environmental and molecular mutagenesis 2002;40(3):175-83.
2001: Hitoshi Ashida; Kaori Kihara; Yuji Nonaka; Itsuko Fukuda; Bunsyo Shiotani; Takashi Hashimoto
The heterocyclic amine, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole induces apoptosis in cocultures of rat parenchymal and nonparenchymal liver cells.
Toxicology and applied pharmacology 2001;177(1):59-67.
2001: Takashi Hashimoto; Hitoshi Ashida; Takashi Sano; Takashi Furuyashiki; Yutaka Hatanaka; K Minato; M Mizuno; K Nomura; A Kumatori; Kazuki Kanazawa; Gen-ichi Danno
3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces caspase-dependent apoptosis in mononuclear cells.
Biochimica et biophysica acta 2001;1539(1-2):44-57.
2001: Bunsyo Shiotani; Yuji Nonaka; Takashi Hashimoto; Kaori Kihara; Kazuki Kanazawa; Gen-ichi Danno; Hitoshi Ashida
DNA-damaging carcinogen 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces apoptosis via caspase-9 in primary cultured rat hepatocytes.
Carcinogenesis 2001;22(5):693-700.
2000: Takashi Hashimoto; Hitoshi Ashida; Takashi Sano; Takashi Furuyashiki; Bunsyo Shiotani; Kazuki Kanazawa; Gen-ichi Danno
3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) induces apoptosis in rat splenocytes and thymocytes by different mechanisms.
Mutation research 2000;457(1-2):57-67.
2000: Mingzhou Sun; Hiroyuki Sakakibara; Hitoshi Ashida; Gen-ichi Danno; Kazuki Kanazawa
Dietary antioxidants fail in protection against oxidative genetic damage in in vitro evaluation.
Bioscience, biotechnology, and biochemistry 2000;64(11):2395-401.
2000: Hitoshi Ashida; Kaori Kihara; Bunsyo Shiotani; Takashi Hashimoto; Kazuki Kanazawa; Gen-ichi Danno
Detection of biomarkers for apoptosis in rat liver after perfusion with 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1).
Bioscience, biotechnology, and biochemistry 2000;64(9):2021-4.
2000: Hitoshi Ashida; Itsuko Fukuda; T Yamashita; Kazuki Kanazawa
Flavones and flavonols at dietary levels inhibit a transformation of aryl hydrocarbon receptor induced by dioxin.
FEBS letters 2000;476(3):213-7.
2000: Mingzhou Sun; Hiroyuki Sakakibara; Hitoshi Ashida; Gen-ichi Danno; Kazuki Kanazawa
Cytochrome P4501A1-inhibitory action of antimutagenic anthraquinones in medicinal plants and the structure-activity relationship.
Bioscience, biotechnology, and biochemistry 2000;64(7):1373-8.
2000: Hitoshi Ashida; Takashi Hashimoto; S Tsuji; Kazuki Kanazawa; Gen-ichi Danno
Synergistic effects of food colors on the toxicity of 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) in primary cultured rat hepatocytes.
Journal of nutritional science and vitaminology 2000;46(3):130-6.
2000: Masashi Mizuno; Y Shiomi; Ken-ichiro Minato; Sachiko Kawakami; Hitoshi Ashida; H Tsuchida
Fucogalactan isolated from Sarcodon aspratus elicits release of tumor necrosis factor-alpha and nitric oxide from murine macrophages.
Immunopharmacology 2000;46(2):113-21.
2000: Hitoshi Ashida
Suppressive effects of flavonoids on dioxin toxicity.
BioFactors (Oxford, England) 2000;12(1-4):201-6.
1999: Kazuki Kanazawa; Hitoshi Ashida; Gen-ichi Danno
Comparison in metabolic activity of cytochrome P450 1A1 on heterocyclic amines between human and rat.
Journal of agricultural and food chemistry 1999;47(12):4956-61.
1998: Hitoshi Ashida; Bunsyo Shiotani; H Adachi; Takashi Hashimoto; Kazuki Kanazawa; Gen-ichi Danno
Tryptophan pyrolysis products, Trp-P-1 and Trp-P-2 induce apoptosis in primary cultured rat hepatocytes.
Bioscience, biotechnology, and biochemistry 1998;62(11):2283-7.
1998: Keiichi Nomura; Hitoshi Ashida; N Uemura; S Kushibe; T Ozaki; M Yoshida
Purification and characterization of a mannose/glucose-specific lectin from Castanea crenata.
Phytochemistry 1998;49(3):667-73.
1998: Kazuki Kanazawa; Hitoshi Ashida
Dietary hydroperoxides of linoleic acid decompose to aldehydes in stomach before being absorbed into the body.
Biochimica et biophysica acta 1998;1393(2-3):349-61.
1998: Kazuki Kanazawa; Hitoshi Ashida
Catabolic fate of dietary trilinoleoylglycerol hydroperoxides in rat gastrointestines.
Biochimica et biophysica acta 1998;1393(2-3):336-48.
1998: Kazuki Kanazawa; T Yamashita; Hitoshi Ashida; Gen-ichi Danno
Antimutagenicity of flavones and flavonols to heterocyclic amines by specific and strong inhibition of the cytochrome P450 1A family.
Bioscience, biotechnology, and biochemistry 1998;62(5):970-7.
1998: Hitoshi Ashida; R Nakai; Kazuki Kanazawa; Gen-ichi Danno
Xenobiotic tolerance of primary cultured hepatocytes in rats fed a high-fat or high-protein diet.
Journal of nutritional science and vitaminology 1998;44(1):89-102.
1997: Hitoshi Ashida; K Ohue; Kazuki Kanazawa; Gen-ichi Danno
Effects of dietary lipid peroxidation products on hormonal responses in primary cultured hepatocytes of rats.
Bioscience, biotechnology, and biochemistry 1997;61(12):2089-94.
1991: Kazuki Kanazawa; Hitoshi Ashida
Target enzymes on hepatic dysfunction caused by dietary products of lipid peroxidation.
Archives of biochemistry and biophysics 1991;288(1):71-8.
1991: Kazuki Kanazawa; Hitoshi Ashida
Relationship between oxidative stress and hepatic phosphoglucomutase activity in rats.
International journal of tissue reactions 1991;13(5):225-31.
1989: Kazuki Kanazawa; Hitoshi Ashida; M Mizuno; M Natake
Depletion of hepatic coenzyme A derivatives is one of the markers of the toxicity of orally administered secondary autoxidation products of linoleic acid in rat.
Journal of nutritional science and vitaminology 1989;35(1):11-23.
1989: Kazuki Kanazawa; Hitoshi Ashida; N Inoue; M Natake
Succinate dehydrogenase and synthetic pathways of glucose 6-phosphate are also the markers of the toxicity of orally administered secondary autoxidation products of linoleic acid in rat liver.
Journal of nutritional science and vitaminology 1989;35(1):25-37.
1988: Kazuki Kanazawa; Hitoshi Ashida; S Minamoto; Gen-ichi Danno; M Natake
The effects of orally administered linoleic acid and its autoxidation products on intestinal mucosa in rat.
Journal of nutritional science and vitaminology 1988;34(4):363-73.
1988: S Minamoto; Kazuki Kanazawa; Hitoshi Ashida; M Natake
Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liver.
Biochimica et biophysica acta 1988;958(2):199-204.
1987: Hitoshi Ashida; Kazuki Kanazawa; S Minamoto; Gen-ichi Danno; M Natake
Effect of orally administered secondary autoxidation products of linoleic acid on carbohydrate metabolism in rat liver.
Archives of biochemistry and biophysics 1987;259(1):114-23.
1986: Kazuki Kanazawa; Hitoshi Ashida; S Minamoto; M Natake
The effect of orally administered secondary autoxidation products of linoleic acid on the activity of detoxifying enzymes in the rat liver.
Biochimica et biophysica acta 1986;879(1):36-43.