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Claude Hélène

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Vladimir A Ryabinin; Alexandre S Boutorine; Claude Hélène; Alexey Yu Denisov; Dmitrii V Pyshnyi; Alexandre N Sinyakov
Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex.
Vladimir A Ryabinin; Alexandre S Boutorine; Claude Hélène; Dmitrii V Pyshnyi; Alexandre N Sinyakov
Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.
Paola B Arimondo; Stéphane Angenault; Ludovic Halby; Alexandre S Boutorine; Frederic Schmidt; Claude Monneret; Thérèse Garestier; Jian-Sheng Sun; Christian Bailly; Claude Hélène
Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates.

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2004: Vladimir A Ryabinin; Alexandre S Boutorine; Claude Hélène; Alexey Yu Denisov; Dmitrii V Pyshnyi; Alexandre N Sinyakov
Oligonucleotide--minor groove binder 1:2 conjugates: side by side parallel minor groove binder motif in stabilization of DNA duplex.
Nucleosides, nucleotides & nucleic acids 2004;23(6-7):953-68.
2004: Vladimir A Ryabinin; Alexandre S Boutorine; Claude Hélène; Dmitrii V Pyshnyi; Alexandre N Sinyakov
Oligonucleotide-minor groove binder conjugates and their complexes with complementary DNA: effect of conjugate structural factors on the thermal stability of duplexes.
Nucleosides, nucleotides & nucleic acids 2004;23(5):789-803.
2003: Paola B Arimondo; Stéphane Angenault; Ludovic Halby; Alexandre S Boutorine; Frederic Schmidt; Claude Monneret; Thérèse Garestier; Jian-Sheng Sun; Christian Bailly; Claude Hélène
Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates.
Nucleic acids research 2003;31(14):4031-40.
2003: Alexandre S Boutorine; Vladimir A Ryabinin; Darya S Novopashina; Alya G Venyaminova; Claude Hélène; A S Sinyakov
Stabilization of DNA double and triple helices by conjugation of minor groove binders to oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):1267-72.
2003: Jian-Sheng Sun; Claude Hélène
Oligonucleotides and derivatives as gene-specific control agents.
Nucleosides, nucleotides & nucleic acids 2003;22(5-8):489-505.
2003: Patrizia Alberti; Laurent Lacroix; Lionel Guittat; Claude Hélène; Jean-Louis Mergny
Nucleic acids as targets for antitelomerase agents.
Mini reviews in medicinal chemistry 2003;3(1):23-36.
2003: Serguei Vinogradov; Victoria Roig; Zinaida A Sergueeva; Chi Hung Nguyen; Paola B Arimondo; Nguyen T Thuong; Emile Bisagni; Jian-Sheng Sun; Claude Hélène; Ulysse Asseline
Synthesis and binding properties of oligo-2'-deoxyribonucleotides conjugated with triple-helix-specific intercalators: benzo[e] and benzo[g] pyridoindoles.
Bioconjugate chemistry 2003;14(1):120-35.
2002: Patrizia Alberti; Paola B Arimondo; Jean-Louis Mergny; Thérèse Garestier; Claude Hélène; Jian-Sheng Sun
A directional nucleation-zipping mechanism for triple helix formation.
Nucleic acids research 2002;30(24):5407-15.
2002: Thibaut Roulon; Claude Hélène; Christophe Escudé
Coupling of a targeting peptide to plasmid DNA using a new type of padlock oligonucleotide.
Bioconjugate chemistry 2002;13(5):1134-9.
2002: Nathalie Dias; Catherine Sénamaud-Beaufort; Erwan le Forestier El; Catherine Auvin; Claude Hélène; Tula Ester Saison-Behmoaras
RNA hairpin invasion and ribosome elongation arrest by mixed base PNA oligomer.
Journal of molecular biology 2002;320(3):489-501.
2002: Günther N Grimm; Alexandre S Boutorine; Per Lincoln; Bengt Nordén; Claude Hélène
Formation of DNA triple helices by an oligonucleotide conjugated to a fluorescent ruthenium complex.
Chembiochem : a European journal of chemical biology 2002;3(4):324-31.
2002: Jean-François Riou; Lionel Guittat; Patrick Mailliet; Abdelazize Laoui; E Renou; O Petitgenet; Frédérique Mégnin-Chanet; Claude Hélène; Jean-Louis Mergny
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(5):2672-7.
2002: Thibaut Roulon; Dominique Coulaud; Etienne Delain; Eric Le Cam; Claude Hélène; Christophe Escudé
Padlock oligonucleotides as a tool for labeling superhelical DNA.
Nucleic acids research 2002;30(3):E12.
2002: Paola B Arimondo; Alexandre S Boutorine; Brigitte Baldeyrou; Christian Bailly; Masayasu Kuwahara; Sidney Hecht; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I.
The Journal of biological chemistry 2002;277(5):3132-40.
2001: Patrizia Alberti; J Ren; Marie-Paule Teulade-Fichou; Lionel Guittat; Jean-François Riou; Jonathan B Chaires; Claude Hélène; Jean-Pierre Vigneron; Jean-Marie Lehn; Jean-Louis Mergny
Interaction of an acridine dimer with DNA quadruplex structures.
Journal of biomolecular structure & dynamics 2001;19(3):505-13.
2001: Paola B Arimondo; Claude Hélène
Design of new anti-cancer agents based on topoisomerase poisons targeted to specific DNA sequences.
Current medicinal chemistry. Anti-cancer agents 2001;1(3):219-35.
2001: Paola B Arimondo; C Bailly; Alexandre S Boutorine; P Moreau; M Prudhomme; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.
Bioconjugate chemistry 2001;12(4):501-9.
2001: Yves Aubert; Loïc Perrouault; Claude Hélène; Carine Giovannangeli; Ulysse Asseline
Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine.
Bioorganic & medicinal chemistry 2001;9(6):1617-24.
2001: Günther N Grimm; Alexandre S Boutorine; P Lincoln; Claude Hélène
Design and simple routes of synthesis of oligonucleotide conjugates for studies of DNA triple helix formation.
Nucleosides, nucleotides & nucleic acids 2001;20(4-7):909-14.
2001: Jean-Louis Mergny; Laurent Lacroix; Marie-Paule Teulade-Fichou; Candide Hounsou; Lionel Guittat; M Hoarau; Paola B Arimondo; Jean-Pierre Vigneron; Jean-Marie Lehn; Jean-François Riou; Thérèse Garestier; Claude Hélène
Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3062-7.
2001: F Koeppel; Jean-François Riou; Abdelazize Laoui; Patrick Mailliet; Paola B Arimondo; D Labit; O Petitgenet; Claude Hélène; Jean-Louis Mergny
Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes.
Nucleic acids research 2001;29(5):1087-96.
2001: DM Perrin; Thérèse Garestier; Claude Hélène
Bridging the gap between proteins and nucleic acids: a metal-independent RNAseA mimic with two protein-like functionalities.
Journal of the American Chemical Society 2001;123(8):1556-63.
2001: Paola B Arimondo; Thérèse Garestier; Claude Hélène; J S Sun
Detection of competing DNA structures by thermal gradient gel electrophoresis: from self-association to triple helix formation by (G,A)-containing oligonucleotides.
Nucleic acids research 2001;29(4):E15.
2001: M Faria; CD Wood; MR White; Claude Hélène; Carine Giovannangeli
Transcription inhibition induced by modified triple helix-forming oligonucleotides: a quantitative assay for evaluation in cells.
Journal of molecular biology 2001;306(1):15-24.
2001: M Faria; D G Spiller; C Dubertret; J S Nelson; MR White; D Scherman; Claude Hélène; Carine Giovannangeli
Phosphoramidate oligonucleotides as potent antisense molecules in cells and in vivo.
Nature biotechnology 2001;19(1):40-4.
2000: Paola B Arimondo; Jean-François Riou; Jean-Louis Mergny; Jamal Tazi; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Interaction of human DNA topoisomerase I with G-quartet structures.
Nucleic acids research 2000;28(24):4832-8.
2000: Carine Giovannangeli; Claude Hélène
Triplex technology takes off.
Nature biotechnology 2000;18(12):1245-6.
2000: Günther N Grimm; Alexandre S Boutorine; Claude Hélène
Rapid routes of synthesis of oligonucleotide conjugates from non-protected oligonucleotides and ligands possessing different nucleophilic or electrophilic functional groups.
Nucleosides, nucleotides & nucleic acids 2000;19(10-12):1943-65.
2000: Nathalie MIGNET; A Brun; C Degert; Brigitte Delord; D Roux; Claude Hélène; René Laversanne; JC François
The spherulites(TM): a promising carrier for oligonucleotide delivery.
Nucleic acids research 2000;28(16):3134-42.
2000: Paola B Arimondo; C Bailly; Alexandre S Boutorine; Ulysse Asseline; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Linkage of a triple helix-forming oligonucleotide to amsacrine-4-carboxamide derivatives modulates the sequence-selectivity of topoisomerase II-mediated DNA cleavage.
Nucleosides, nucleotides & nucleic acids 2000;19(8):1205-18.
2000: Carine Giovannangeli; Claude Hélène
Triplex-forming molecules for modulation of DNA information processing.
Current opinion in molecular therapeutics 2000;2(3):288-96.
2000: C Marchand; Chi Hung Nguyen; B Ward; Jian-Sheng Sun; Emile Bisagni; Thérèse Garestier; Claude Hélène
A new family of sequence-specific DNA-cleaving agents directed by triple-helical structures: benzopyridoindole-EDTA conjugates.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(9):1559-63.
2000: Laurent Lacroix; Paola B Arimondo; Masashi Takasugi; Claude Hélène; Jean-Louis Mergny
Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions.
Biochemical and biophysical research communications 2000;270(2):363-9.
2000: Paola B Arimondo; P Moreau; Alexandre S Boutorine; C Bailly; M Prudhomme; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides.
Bioorganic & medicinal chemistry 2000;8(4):777-84.
2000: Laurent Lacroix; H Liénard; E Labourier; M Djavaheri-Mergny; Jérôme Lacoste; H Leffers; Jamal Tazi; Claude Hélène; Jean-Louis Mergny
Identification of two human nuclear proteins that recognise the cytosine-rich strand of human telomeres in vitro.
Nucleic acids research 2000;28(7):1564-75.
2000: AL Guieysse; Danièle Praseuth; Carine Giovannangeli; Ulysse Asseline; Claude Hélène
Psoralen adducts induced by triplex-forming oligonucleotides are refractory to repair in HeLa cells.
Journal of molecular biology 2000;296(2):373-83.
1999: Danièle Praseuth; AL Guieysse; Claude Hélène
Triple helix formation and the antigene strategy for sequence-specific control of gene expression.
Biochimica et biophysica acta 1999;1489(1):181-206.
1999: Christine Vever-Bizet; Alexandre S Boutorine; O Delgado; Daniel Brault; Claude Hélène
Targeting of HIV gp120 by oligonucleotide-photosensitizer conjugates. Light-induced damages.
FEBS letters 1999;462(3):467-71.
1999: S Dheur; Nathalie Dias; A van Aerschot; P Herdewijn; T Bettinger; J S Rémy; Claude Hélène; E T Saison-Behmoaras
Polyethylenimine but not cationic lipid improves antisense activity of 3'-capped phosphodiester oligonucleotides.
Antisense & nucleic acid drug development 1999;9(6):515-25.
1999: Nathalie Dias; S Dheur; P E Nielsen; S Gryaznov; A Van Aerschot; P Herdewijn; Claude Hélène; TE Saison-Behmoaras
Antisense PNA tridecamers targeted to the coding region of Ha-ras mRNA arrest polypeptide chain elongation.
Journal of molecular biology 1999;294(2):403-16.
1999: Rula Zain; C Marchand; J Sun; Chi Hung Nguyen; Emile Bisagni; Thérèse Garestier; Claude Hélène
Design of a triple-helix-specific cleaving reagent.
Chemistry & biology 1999;6(11):771-7.
1999: Christophe Escudé; Thérèse Garestier; Claude Hélène
Padlock oligonucleotides for duplex DNA based on sequence-specific triple helix formation.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(19):10603-7.
1999: Martin Mills; Paola B Arimondo; Laurent Lacroix; Thérèse Garestier; Claude Hélène; Horst H Klump; Jean-Louis Mergny
Energetics of strand-displacement reactions in triple helices: a spectroscopic study.
Journal of molecular biology 1999;291(5):1035-54.
1999: Paola B Arimondo; C Bailly; Alexandre S Boutorine; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1999;322(9):785-90.
1999: Jean-Louis Mergny; Patrick Mailliet; F Lavelle; Jean-François Riou; Abdelazize Laoui; Claude Hélène
The development of telomerase inhibitors: the G-quartet approach.
Anti-cancer drug design 1999;14(4):327-39.
1999: JC François; Claude Hélène
Recognition of hairpin-containing single-stranded DNA by oligonucleotides containing internal acridine derivatives.
Bioconjugate chemistry 1999;10(3):439-46.
1999: Y Hamel; Jérôme Lacoste; C Frayssinet; A Sarasin; Thérèse Garestier; JC François; Claude Hélène
Inhibition of gene expression by anti-sense C-5 propyne oligonucleotides detected by a reporter enzyme.
The Biochemical journal 1999;339 ( Pt 3)():547-53.
1999: DM Perrin; Thérèse Garestier; Claude Hélène
Expanding the catalytic repertoire of nucleic acid catalysts: simultaneous incorporation of two modified deoxyribonucleoside triphosphates bearing ammonium and imidazolyl functionalities.
Nucleosides & nucleotides 1999;18(3):377-91.
1999: FX Barre; Carine Giovannangeli; Claude Hélène; Annick Harel-Bellan
Covalent crosslinks introduced via a triple helix-forming oligonucleotide coupled to psoralen are inefficiently repaired.
Nucleic acids research 1999;27(3):743-9.
1998: Thérèse de Bizemont; J S Sun; Thérèse Garestier; Claude Hélène
New junction models for alternate-strand triple-helix formation.
Chemistry & biology 1998;5(12):755-62.
1998: Paola B Arimondo; F Barcelo; Jian-Sheng Sun; J C Maurizot; Thérèse Garestier; Claude Hélène
Triple helix formation by (G,A)-containing oligonucleotides: asymmetric sequence effect.
Biochemistry 1998;37(47):16627-35.
1998: C Marchand; Jian-Sheng Sun; C Bailly; M J Waring; Thérèse Garestier; Claude Hélène
Optimization of alternate-strand triple helix formation at the 5'CpG3' and 5'GpC3' junction steps.
Biochemistry 1998;37(38):13322-9.
1998: G Duval-Valentin; Masashi Takasugi; Claude Hélène; E Sage
Triple helix-directed psoralen crosslinks are recognized by Uvr(A)BC excinuclease.
Journal of molecular biology 1998;278(4):815-25.
1998: Christophe Escudé; Chi Hung Nguyen; S Kukreti; Y Janin; Jian-Sheng Sun; Emile Bisagni; Thérèse Garestier; Claude Hélène
Rational design of a triple helix-specific intercalating ligand.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3591-6.
1997: S Kukreti; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Extension of the range of DNA sequences available for triple helix formation: stabilization of mismatched triplexes by acridine-containing oligonucleotides.
Nucleic acids research 1997;25(21):4264-70.
1997: Carine Giovannangeli; Claude Hélène
Progress in developments of triplex-based strategies.
Antisense & nucleic acid drug development 1997;7(4):413-21.
1997: TE Saison-Behmoaras; I Duroux; T T Nguyen; Ulysse Asseline; Claude Hélène
Antisense properties of end-modified oligonucleotides targeted to Ha-ras oncogene.
Antisense & nucleic acid drug development 1997;7(4):361-8.
1997: Jérôme Lacoste; JC François; Claude Hélène
Triple helix formation with purine-rich phosphorothioate-containing oligonucleotides covalently linked to an acridine derivative.
Nucleic acids research 1997;25(10):1991-8.
1997: B Zhou-Sun; J Sun; S M Gryaznov; Jean Liquier; Thérèse Garestier; Claude Hélène; Eliane Taillandier
A physico-chemical study of triple helix formation by an oligodeoxythymidylate with N3'--> P5' phosphoramidate linkages.
Nucleic acids research 1997;25(9):1782-7.
1997: AL Guieysse; Danièle Praseuth; Claude Hélène
Identification of a triplex DNA-binding protein from human cells.
Journal of molecular biology 1997;267(2):289-98.
1997: Claude Hélène
[The "antisense" strategy: a new approach in the development of antineoplastic substances and gene therapy].
Journal de pharmacie de Belgique 1997;52(2):79-85.
1997: Claude Hélène; Carine Giovannangeli; A L Guieysse-Peugeot; Danièle Praseuth
Sequence-specific control of gene expression by antigene and clamp oligonucleotides.
Ciba Foundation symposium 1997;209():94-102; discussion 102-6.
1997: G C Silver; Chi Hung Nguyen; Alexandre S Boutorine; Emile Bisagni; Thérèse Garestier; Claude Hélène
Conjugates of oligonucleotides with triplex-specific intercalating agents. Stabilization of triple-helical DNA in the promoter region of the gene for the alpha-subunit of interleukin 2 (IL-2R alpha).
Bioconjugate chemistry 1997;8(1):15-22.
1996: Danièle Praseuth; M Grigoriev; AL Guieysse; Linda L Pritchard; Annick Harel-Bellan; P E Nielsen; Claude Hélène
Peptide nucleic acids directed to the promoter of the alpha-chain of the interleukin-2 receptor.
Biochimica et biophysica acta 1996;1309(3):226-38.
1996: AL Guieysse; Danièle Praseuth; M Grigoriev; Annick Harel-Bellan; Claude Hélène
Detection of covalent triplex within human cells.
Nucleic acids research 1996;24(21):4210-6.
1996: C Giovannangeli; L Perrouault; Christophe Escudé; S Gryaznov; Claude Hélène
Efficient inhibition of transcription elongation in vitro by oligonucleotide phosphoramidates targeted to proviral HIV DNA.
Journal of molecular biology 1996;261(3):386-98.
1996: C Giovannangeli; L Perrouault; Christophe Escudé; T Nguyen; Claude Hélène
Specific inhibition of in vitro transcription elongation by triplex-forming oligonucleotide-intercalator conjugates targeted to HIV proviral DNA.
Biochemistry 1996;35(32):10539-48.
1996: Laurent Lacroix; Jean-Louis Mergny; JL Leroy; Claude Hélène
Inability of RNA to form the i-motif: implications for triplex formation.
Biochemistry 1996;35(26):8715-22.
1996: Claude Hélène
[Nucleic acids, specific control agents of gene expression. From chemistry to clinics].
Thérapie 1996;51(4):361-2.
1996: J S Sun; Thérèse Garestier; Claude Hélène
Oligonucleotide directed triple helix formation.
Current opinion in structural biology 1996;6(3):327-33.
1996: Christophe Escudé; Jian-Sheng Sun; Chi Hung Nguyen; Emile Bisagni; Thérèse Garestier; Claude Hélène
Ligand-induced formation of triple helices with antiparallel third strands containing G and T.
Biochemistry 1996;35(18):5735-40.
1996: Christophe Escudé; C Giovannangeli; Jian-Sheng Sun; D H Lloyd; J K Chen; S M Gryaznov; Thérèse Garestier; Claude Hélène
Stable triple helices formed by oligonucleotide N3'-->P5' phosphoramidates inhibit transcription elongation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4365-9.
1996: C Marchand; Christian Bailly; Chi Hung Nguyen; Emile Bisagni; Thérèse Garestier; Claude Hélène; Michael J Waring
Stabilization of triple helical DNA by a benzopyridoquinoxaline intercalator.
Biochemistry 1996;35(15):5022-32.
1996: Thérèse de Bizemont; G Duval-Valentin; Jian-Sheng Sun; Emile Bisagni; Thérèse Garestier; Claude Hélène
Alternate strand recognition of double-helical DNA by (T,G)-containing oligonucleotides in the presence of a triple helix-specific ligand.
Nucleic acids research 1996;24(6):1136-43.
1996: Christophe Escudé; S Mohammadi; Jian-Sheng Sun; Chi Hung Nguyen; Emile Bisagni; Jean Liquier; Eliane Taillandier; Thérèse Garestier; Claude Hélène
Ligand-induced formation of hoogsteen-paired parallel DNA.
Chemistry & biology 1996;3(1):57-65.
1995: S B Noonberg; JC François; D Praseuth; A L Guieysse-Peugeot; Jérôme Lacoste; Thérèse Garestier; Claude Hélène
Triplex formation with alpha anomers of purine-rich and pyrimidine-rich oligodeoxynucleotides.
Nucleic acids research 1995;23(20):4042-9.
1995: I Duroux; G Godard; M Boidot-Forget; G Schwab; Claude Hélène; TE Saison-Behmoaras
Rational design of point mutation-selective antisense DNA targeted to codon 12 of Ha-ras mRNA in human cells.
Nucleic acids research 1995;23(17):3411-8.
1995: B W Zhou; C Marchand; Ulysse Asseline; Nguyen T Thuong; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène
Recognition of alternating oligopurine/oligopyrimidine tracts of DNA by oligonucleotides with base-to-base linkages.
Bioconjugate chemistry 1995;6(5):516-23.
1995: G Godard; A S Boutorine; E Saison-Behmoaras; Claude Hélène
Antisense effects of cholesterol-oligodeoxynucleotide conjugates associated with poly(alkylcyanoacrylate) nanoparticles.
European journal of biochemistry / FEBS 1995;232(2):404-10.
1995: Christian Bailly; C Marchand; C Hung Nguyen; Emile Bisagni; Thérèse Garestier; Claude Hélène; Michael J Waring
Localized chemical reactivity in double-stranded DNA associated with the intercalative binding of benzo[e]pyridoindole and benzo[g]pyridoindole triple-helix-stabilizing ligands.
European journal of biochemistry / FEBS 1995;232(1):66-76.
1995: AL Guieysse; Danièle Praseuth; M Grigoriev; Annick Harel-Bellan; Claude Hélène
Oligonucleotide-directed switching of DNA polymerases to a dead-end track.
Biochemistry 1995;34(28):9193-9.
1995: S B Noonberg; JC François; Thérèse Garestier; Claude Hélène
Effect of competing self-structure on triplex formation with purine-rich oligodeoxynucleotides containing GA repeats.
Nucleic acids research 1995;23(11):1956-63.
1995: G Duval-Valentin; Thérèse de Bizemont; M Takasugi; Jean-Louis Mergny; Emile Bisagni; Claude Hélène
Triple-helix specific ligands stabilize H-DNA conformation.
Journal of molecular biology 1995;247(5):847-58.
1995: JC François; Claude Hélène
Recognition and cleavage of single-stranded DNA containing hairpin structures by oligonucleotides forming both Watson-Crick and Hoogsteen hydrogen bonds.
Biochemistry 1995;34(1):65-72.
1994: Christian Bailly; C Michaux; Pierre Colson; Claude Houssier; Jian-Sheng Sun; Thérèse Garestier; Claude Hélène; Jean-Pierre Hénichart; C Rivalle; Emile Bisagni
Reaction of a biscationic distamycin-ellipticine hybrid ligand with DNA. Mode and sequence specificity of binding.
Biochemistry 1994;33(51):15348-64.
1994: Jean-Louis Mergny; Thérèse Garestier; M Rougée; A V Lebedev; M Chassignol; Nguyen T Thuong; Claude Hélène
Fluorescence energy transfer between two triple helix-forming oligonucleotides bound to duplex DNA.
Biochemistry 1994;33(51):15321-8.
1994: G Godard; JC François; I Duroux; Ulysse Asseline; M Chassignol; T Nguyen; Claude Hélène; TE Saison-Behmoaras
Photochemically and chemically activatable antisense oligonucleotides: comparison of their reactivities towards DNA and RNA targets.
Nucleic acids research 1994;22(22):4789-95.
1994: G Schwab; C Chavany; I Duroux; Gérard Goubin; J Lebeau; Claude Hélène; TE Saison-Behmoaras
Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(22):10460-4.
1994: JC François; Nguyen T Thuong; Claude Hélène
Recognition and cleavage of hairpin structures in nucleic acids by oligodeoxynucleotides.
Nucleic acids research 1994;22(19):3943-50.
1994: C Chavany; TE Saison-Behmoaras; T Le Doan; F Puisieux; P Couvreur; Claude Hélène
Adsorption of oligonucleotides onto polyisohexylcyanoacrylate nanoparticles protects them against nucleases and increases their cellular uptake.
Pharmaceutical research 1994;11(9):1370-8.
1994: P Cros; R Kurfürst; P Allibert; Nicole Battail; N Piga; V Roig; Nguyen T Thuong; Bernard Mandrand; Claude Hélène
Monoclonal antibodies targeted to alpha-oligonucleotides. Characterisation and application in nucleic acid detection.
Nucleic acids research 1994;22(15):2951-7.
1994: JL Leroy; Maurice Guéron; Jean-Louis Mergny; Claude Hélène
Intramolecular folding of a fragment of the cytosine-rich strand of telomeric DNA into an i-motif.
Nucleic acids research 1994;22(9):1600-6.
1994: G Schwab; I Duroux; C Chavany; Claude Hélène; E Saison-Behmoaras
An approach for new anticancer drugs: oncogene-targeted antisense DNA.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5 Suppl 4():55-8.
1994: Claude Hélène
Control of oncogene expression by antisense nucleic acids.
European journal of cancer (Oxford, England : 1990) 1994;30A(11):1721-6.
1993: Christophe Escudé; JC François; Jian-Sheng Sun; G Ott; M Sprinzl; Thérèse Garestier; Claude Hélène
Stability of triple helices containing RNA and DNA strands: experimental and molecular modeling studies.
Nucleic acids research 1993;21(24):5547-53.
1993: C Giovannangeli; Nguyen T Thuong; Claude Hélène
Oligonucleotide clamps arrest DNA synthesis on a single-stranded DNA target.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(21):10013-7.
1993: A Jacob; G Duval-Valentin; D Ingrand; Nguyen T Thuong; Claude Hélène
Inhibition of viral growth by an alpha-oligonucleotide directed to the splice junction of herpes simplex virus type-1 immediate-early pre-mRNA species 22 and 47.
European journal of biochemistry / FEBS 1993;216(1):19-24.
1993: Daniel S Pilch; Michael J Waring; Jian-Sheng Sun; M Rougée; Chi Hung Nguyen; Emile Bisagni; Thérèse Garestier; Claude Hélène
Characterization of a triple helix-specific ligand. BePI (3-methoxy-7H-8-methyl-11- [(3'-amino)propylamino]-benzo[e]pyrido[4,3-b]indole) intercalates into both double-helical and triple-helical DNA.
Journal of molecular biology 1993;232(3):926-46.
1993: M Grigoriev; Danièle Praseuth; AL Guieysse; Philippe Robin; Nguyen T Thuong; Claude Hélène; Annick Harel-Bellan
Inhibition of gene expression by triple helix-directed DNA cross-linking at specific sites.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3501-5.
1993: Claude Hélène
Sequence-selective recognition and cleavage of double-helical DNA.
Current opinion in biotechnology 1993;4(1):29-36.
1993: Danièle Praseuth; AL Guieysse; A V Itkes; Claude Hélène
Unexpected effect of an anti-human immunodeficiency virus intermolecular triplex-forming oligonucleotide in an in vitro transcription system due to RNase H-induced cleavage of the RNA transcript.
Antisense research and development 1993;3(1):33-44.
1993: M Grigoriev; Danièle Praseuth; AL Guieysse; Philippe Robin; Nguyen T Thuong; Claude Hélène; Annick Harel-Bellan
Inhibition of interleukin-2 receptor alpha-subunit gene expression by oligonucleotide-directed triple helix formation.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1993;316(5):492-5.
1992: C Bourdouxhe; Pierre Colson; Claude Houssier; Jian-Sheng Sun; T Montenay-Garestier; Claude Hélène; C Rivalle; Emile Bisagni; Michael J Waring; Jean-Pierre Hénichart
Binding of a distamycin-ellipticine hybrid molecule to DNA and chromatin: spectroscopic, biochemical, and molecular modeling investigations.
Biochemistry 1992;31(49):12385-96.
1992: J Chomilier; Jian-Sheng Sun; D A Collier; T Garestier; Claude Hélène; R Lavery
A computational and experimental study of the bending induced at a double-triple helix junction.
Biophysical chemistry 1992;45(2):143-52.
1992: M Rougée; B Faucon; Jean-Louis Mergny; F Barcelo; C Giovannangeli; Thérèse Garestier; Claude Hélène
Kinetics and thermodynamics of triple-helix formation: effects of ionic strength and mismatches.
Biochemistry 1992;31(38):9269-78.
1992: C Giovannangéli; M Rougée; Thérèse Garestier; Nguyen T Thuong; Claude Hélène
Triple-helix formation by oligonucleotides containing the three bases thymine, cytosine, and guanine.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8631-5.
1992: C Giovannangéli; Nguyen T Thuong; Claude Hélène
Oligodeoxynucleotide-directed photo-induced cross-linking of HIV proviral DNA via triple-helix formation.
Nucleic acids research 1992;20(16):4275-81.
1992: Jean-Louis Mergny; G Duval-Valentin; Chi Hung Nguyen; L Perrouault; B Faucon; M Rougée; T Montenay-Garestier; Emile Bisagni; Claude Hélène
Triple helix-specific ligands.
Science (New York, N.Y.) 1992;256(5064):1681-4.
1992: A S Boutorine; Claudine Boiziau; T Le Doan; Jean-Jacques Toulmé; Claude Hélène
Effect of the terminal phosphate derivatization of beta- and alpha-oligodeoxynucleotides on their antisense activity in protein biosynthesis, stability and uptake by eucaryotic cells.
Biochimie 1992;74(5):485-9.
1992: C Chavany; T Le Doan; P Couvreur; F Puisieux; Claude Hélène
Polyalkylcyanoacrylate nanoparticles as polymeric carriers for antisense oligonucleotides.
Pharmaceutical research 1992;9(4):441-9.
1992: M Grigoriev; Danièle Praseuth; Philippe Robin; A Hemar; TE Saison-Behmoaras; Alice Dautry-Varsat; Nguyen T Thuong; Claude Hélène; Annick Harel-Bellan
A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence.
The Journal of biological chemistry 1992;267(5):3389-95.
1992: G Duval-Valentin; Nguyen T Thuong; Claude Hélène
Specific inhibition of transcription by triple helix-forming oligonucleotides.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(2):504-8.
1992: Christophe Escudé; Jian-Sheng Sun; M Rougée; Thérèse Garestier; Claude Hélène
Stable triple helices are formed upon binding of RNA oligonucleotides and their 2'-O-methyl derivatives to double-helical DNA.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1992;315(13):521-5.
1991: Jian-Sheng Sun; R Lavery; J Chomilier; K Zakrzewska; T Montenay-Garestier; Claude Hélène
Theoretical study of ethidium intercalation in triple-stranded DNA and at triplex-duplex junctions.
Journal of biomolecular structure & dynamics 1991;9(3):425-436.
1991: Jian-Sheng Sun; Jean-Louis Mergny; R Lavery; T Montenay-Garestier; Claude Hélène
Triple helix structures: sequence dependence, flexibility and mismatch effects.
Journal of biomolecular structure & dynamics 1991;9(3):411-24.
1991: Claude Hélène
The anti-gene strategy: control of gene expression by triplex-forming-oligonucleotides.
Anti-cancer drug design 1991;6(6):569-84.
1991: Jean-Louis Mergny; Jian-Sheng Sun; M Rougée; T Montenay-Garestier; F Barcelo; J Chomilier; Claude Hélène
Sequence specificity in triple-helix formation: experimental and theoretical studies of the effect of mismatches on triplex stability.
Biochemistry 1991;30(40):9791-8.
1991: Claude Hélène; T Le Doan
Oligonucleotides: problems and frontiers of practical applications.
Trends in biotechnology 1991;9(10):339-40.
1991: Jian-Sheng Sun; C Giovannangeli; JC François; R Kurfurst; T Montenay-Garestier; Ulysse Asseline; TE Saison-Behmoaras; Nguyen T Thuong; Claude Hélène
Triple-helix formation by alpha oligodeoxynucleotides and alpha oligodeoxynucleotide-intercalator conjugates.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(14):6023-7.
1991: M Takasugi; A Guendouz; M Chassignol; J L Decout; Jean Lhomme; Nguyen T Thuong; Claude Hélène
Sequence-specific photo-induced cross-linking of the two strands of double-helical DNA by a psoralen covalently linked to a triple helix-forming oligonucleotide.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5602-6.
1991: TE Saison-Behmoaras; B Tocqué; I Rey; M Chassignol; Nguyen T Thuong; Claude Hélène
Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation.
The EMBO journal 1991;10(5):1111-8.
1991: Jean-Louis Mergny; D Collier; M Rougée; T Montenay-Garestier; Claude Hélène
Intercalation of ethidium bromide into a triple-stranded oligonucleotide.
Nucleic acids research 1991;19(7):1521-6.
1991: Jean-Louis Mergny; A Slama-Schwok; T Montenay-Garestier; M Rougée; Claude Hélène
Fluorescence energy transfer between dimethyldiazaperopyrenium dication and ethidium intercalated in poly d(A-T).
Photochemistry and photobiology 1991;53(4):555-8.
1991: T Montenay-Garestier; Claude Hélène; Nguyen T Thuong
Design of sequence-specific bifunctional nucleic acid ligands.
Ciba Foundation symposium 1991;158():147-57; discussion 204-12.
1991: A S Boutorine; T Le Doan; J P Battioni; Claude Hélène
Optimization of synthesis of 5'-porphyrin-oligonucleotide conjugates and studies of their interaction with eukaryotic cells.
Nucleic acids symposium series 1991;(24):273.
1991: S de Falco; A Boutorine; C de Smidt; Theo Van berkel; E Saison; Claude Hélène; T Le Doan
Utilization of antisense oligonucleotides in vivo: stability and internalization of hydrophobized oligonucleotides.
Nucleic acids symposium series 1991;(24):157-8.
1991: Claude Hélène
Rational design of sequence-specific oncogene inhibitors based on antisense and antigene oligonucleotides.
European journal of cancer (Oxford, England : 1990) 1991;27(11):1466-71.
1991: T Le Doan; L Perrouault; Ulysse Asseline; Nguyen T Thuong; C Rivalle; Emile Bisagni; Claude Hélène
Recognition and photo-induced cleavage and cross-linking of nucleic acids by oligonucleotides covalently linked to ellipticine.
Antisense research and development 1991;1(1):43-54.
1991: Jian-Sheng Sun; Thérèse de Bizemont; G Duval-Valentin; T Montenay-Garestier; Claude Hélène
Extension of the range of recognition sequences for triple helix formation by oligonucleotides containing guanines and thymines.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1991;313(13):585-90.
1990: A S Boutorine; T Le Doan; J P Battioni; Daniel Mansuy; D Dupré; Claude Hélène
Rapid routes of synthesis of chemically reactive and highly radioactively labeled alpha- and beta-oligonucleotide derivatives for in vivo studies.
Bioconjugate chemistry 1990;1(5):350-6.
1990: Claude Hélène; J J Toulmé
Specific regulation of gene expression by antisense, sense and antigene nucleic acids.
Biochimica et biophysica acta 1990;1049(2):99-125.
1990: F Birg; Danièle Praseuth; A Zerial; Nguyen T Thuong; Ulysse Asseline; T Le Doan; Claude Hélène
Inhibition of simian virus 40 DNA replication in CV-1 cells by an oligodeoxynucleotide covalently linked to an intercalating agent.
Nucleic acids research 1990;18(10):2901-8.
1990: L Perrouault; Ulysse Asseline; C Rivalle; Nguyen T Thuong; Emile Bisagni; C Giovannangeli; T Le Doan; Claude Hélène
Sequence-specific artificial photo-induced endonucleases based on triple helix-forming oligonucleotides.
Nature 1990;344(6264):358-60.
1990: T Le Doan; Danièle Praseuth; L Perrouault; M Chassignol; Nguyen T Thuong; Claude Hélène
Sequence-targeted photochemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins.
Bioconjugate chemistry 1990;1(2):108-13.
1989: JC François; TE Saison-Behmoaras; Nguyen T Thuong; Claude Hélène
Inhibition of restriction endonuclease cleavage via triple helix formation by homopyrimidine oligonucleotides.
Biochemistry 1989;28(25):9617-9.
1989: Jian-Sheng Sun; JC François; T Montenay-Garestier; TE Saison-Behmoaras; V Roig; Nguyen T Thuong; Claude Hélène
Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(23):9198-202.
1989: JC François; TE Saison-Behmoaras; C Barbier; M Chassignol; Nguyen T Thuong; Claude Hélène
Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9702-6.
1989: D G Searcy; T Montenay-Garestier; Claude Hélène
Phenylalanine-to-tyrosine singlet energy transfer in the archaebacterial histone-like protein HTa.
Biochemistry 1989;28(23):9058-65.
1989: C Cazenave; Cy A Stein; N Loreau; Nguyen T Thuong; Leonard M Neckers; C Subasinghe; Claude Hélène; J S Cohen; Jean-Jacques Toulmé
Comparative inhibition of rabbit globin mRNA translation by modified antisense oligodeoxynucleotides.
Nucleic acids research 1989;17(11):4255-73.
1989: A Slama-Schwok; M Rougée; V Ibanez; N E Geacintov; T Montenay-Garestier; Jean-Marie Lehn; Claude Hélène
Interactions of the dimethyldiazaperopyrenium dication with nucleic acids. 2. Binding to double-stranded polynucleotides.
Biochemistry 1989;28(8):3234-42.
1989: A Slama-Schwok; J Jazwinski; A Béré; T Montenay-Garestier; M Rougée; Claude Hélène; Jean-Marie Lehn
Interactions of the dimethyldiazaperopyrenium dication with nucleic acids. 1. Binding to nucleic acid components and to single-stranded polynucleotides and photocleavage of single-stranded oligonucleotides.
Biochemistry 1989;28(8):3227-34.
1988: JC François; TE Saison-Behmoaras; Claude Hélène
Sequence-specific recognition of the major groove of DNA by oligodeoxynucleotides via triple helix formation. Footprinting studies.
Nucleic acids research 1988;16(24):11431-40.
1988: M Boidot-Forget; M Chassignol; M Takasugi; Nguyen T Thuong; Claude Hélène
Site-specific cleavage of single-stranded and double-stranded DNA sequences by oligodeoxyribonucleotides covalently linked to an intercalating agent and an EDTA-Fe chelate.
Gene 1988;72(1-2):361-71.
1988: Catherine Jessus; M Chevrier; René Ozon; Claude Hélène; C Cazenave
Specific inhibition of beta-tubulin synthesis in Xenopus oocytes using anti-sense oligodeoxyribonucleotides.
Gene 1988;72(1-2):311-2.
1988: Jian-Sheng Sun; JC François; R Lavery; TE Saison-Behmoaras; T Montenay-Garestier; Nguyen T Thuong; Claude Hélène
Sequence-targeted cleavage of nucleic acids by oligo-alpha-thymidylate-phenanthroline conjugates: parallel and antiparallel double helices are formed with DNA and RNA, respectively.
Biochemistry 1988;27(16):6039-45.
1988: Danièle Praseuth; T Le Doan; M Chassignol; J L Decout; N Habhoub; Jean Lhomme; Nguyen T Thuong; Claude Hélène
Sequence-targeted photosensitized reactions in nucleic acids by oligo-alpha-deoxynucleotides and oligo-beta-deoxynucleotides covalently linked to proflavin.
Biochemistry 1988;27(8):3031-8.
1988: JC François; TE Saison-Behmoaras; M Chassignol; Nguyen T Thuong; Jian-Sheng Sun; Claude Hélène
Periodic cleavage of poly(dA) by oligothymidylates covalently linked to the 1,10-phenanthroline-copper complex.
Biochemistry 1988;27(7):2272-6.
1988: Catherine Jessus; C Cazenave; René Ozon; Claude Hélène
Specific inhibition of endogenous beta-tubulin synthesis in Xenopus oocytes by anti-messenger oligodeoxynucleotides.
Nucleic acids research 1988;16(5):2225-33.
1988: Danièle Praseuth; L Perrouault; T Le Doan; M Chassignol; Nguyen T Thuong; Claude Hélène
Sequence-specific binding and photocrosslinking of alpha and beta oligodeoxynucleotides to the major groove of DNA via triple-helix formation.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1349-53.
1988: JC François; TE Saison-Behmoaras; M Chassignol; Nguyen T Thuong; Claude Hélène
[Artificial nucleases: specific cleavage of the double helix of DNA by oligonucleotides linked to copper-phenanthroline complex].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1988;307(20):849-54.
1987: C Cazenave; M Chevrier; T T Nguyen; Claude Hélène
Rate of degradation of [alpha]- and [beta]-oligodeoxynucleotides in Xenopus oocytes. Implications for anti-messenger strategies.
Nucleic acids research 1987;15(24):10507-21.
1987: L Perrouault; M Chassignol; T T Nguyen; Claude Hélène
Sequence-targeted chemical modifications of nucleic acids by complementary oligonucleotides covalently linked to porphyrins.
Nucleic acids research 1987;15(21):8643-59.
1987: M R Rajeswari; T Montenay-Garestier; Claude Hélène
Does tryptophan intercalate in DNA? A comparative study of peptide binding to alternating and nonalternating A.T sequences.
Biochemistry 1987;26(21):6825-31.
1987: T Le Doan; L Perrouault; Danièle Praseuth; N Habhoub; J L Decout; Nguyen T Thuong; Jean Lhomme; Claude Hélène
Sequence-specific recognition, photocrosslinking and cleavage of the DNA double helix by an oligo-[alpha]-thymidylate covalently linked to an azidoproflavine derivative.
Nucleic acids research 1987;15(19):7749-60.
1987: Danièle Praseuth; M Chassignol; M Takasugi; T Le Doan; Nguyen T Thuong; Claude Hélène
Double helices with parallel strands are formed by nuclease-resistant oligo-[alpha]-deoxynucleotides and oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent with complementary oligo-[beta]-deoxynucleotides.
Journal of molecular biology 1987;196(4):939-42.
1987: Jian-Sheng Sun; Ulysse Asseline; D Rouzaud; T Montenay-Garestier; T T Nguyen; Claude Hélène
Oligo-[alpha]-deoxynucleotides covalently linked to an intercalating agent. Double helices with parallel strands are formed with complementary oligo-[beta]-deoxynucleotides.
Nucleic acids research 1987;15(15):6149-58.
1987: Nguyen T Thuong; Ulysse Asseline; V Roig; M Takasugi; Claude Hélène
Oligo(alpha-deoxynucleotide)s covalently linked to intercalating agents: differential binding to ribo- and deoxyribopolynucleotides and stability towards nuclease digestion.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(15):5129-33.
1987: C Cazenave; N Loreau; Nguyen T Thuong; Jean-Jacques Toulmé; Claude Hélène
Enzymatic amplification of translation inhibition of rabbit beta-globin mRNA mediated by anti-messenger oligodeoxynucleotides covalently linked to intercalating agents.
Nucleic acids research 1987;15(12):4717-36.
1987: M Chabbert; C Cazenave; Claude Hélène
Kinetic studies of recA protein binding to a fluorescent single-stranded polynucleotide.
Biochemistry 1987;26(8):2218-25.
1987: P Verspieren; A W Cornelissen; Nguyen T Thuong; Claude Hélène; Jean-Jacques Toulmé
An acridine-linked oligodeoxynucleotide targeted to the common 5' end of trypanosome mRNAs kills cultured parasites.
Gene 1987;61(3):307-15.
1986: M Boidot-Forget; TE Saison-Behmoaras; Jean-Jacques Toulmé; Claude Hélène
Single-strand binding proteins from phage T4 and E. coli form higher order structures with poly(dT).
Biochimie 1986;68(9):1129-34.
1986: C Cazenave; N Loreau; Jean-Jacques Toulmé; Claude Hélène
Anti-messenger oligodeoxynucleotides: specific inhibition of rabbit beta-globin synthesis in wheat germ extracts and Xenopus oocytes.
Biochimie 1986;68(9):1063-9.
1986: Gérard Lancelot; Ulysse Asseline; Nguyen T Thuong; Claude Hélène
31P NMR studies of the binding of the oligonucleotide (Ap)3A to an oligodeoxythymidylate covalently linked to an acridine derivative.
Journal of biomolecular structure & dynamics 1986;3(5):913-21.
1986: Jean-Jacques Toulmé; H M Krisch; N Loreau; Nguyen T Thuong; Claude Hélène
Specific inhibition of mRNA translation by complementary oligonucleotides covalently linked to intercalating agents.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(5):1227-31.
1985: T Le Doan; M Guigues; Jean-Jacques Toulmé; Claude Hélène
Specific recognition by the tripeptide lysyl-tryptophyl-alpha-lysine of structural damage induced in DNA by platinum derivatives.
Biochimica et biophysica acta 1985;825(4):353-9.
1985: Claude Hélène; T Montenay-Garestier; T Saison; M Takasugi; Jean-Jacques Toulmé; Ulysse Asseline; Gérard Lancelot; Jean-Claude Maurizot; F Toulmé; Nguyen T Thuong
Oligodeoxynucleotides covalently linked to intercalating agents: a new class of gene regulatory substances.
Biochimie 1985;67(7-8):777-83.
1985: Gérard Lancelot; Ulysse Asseline; Nguyen T Thuong; Claude Hélène
Proton and phosphorus nuclear magnetic resonance studies of an oligothymidylate covalently linked to an acridine derivative and of its binding to complementary sequences.
Biochemistry 1985;24(10):2521-9.
1984: Ulysse Asseline; M Delarue; Gérard Lancelot; F Toulmé; Nguyen T Thuong; T Montenay-Garestier; Claude Hélène
Nucleic acid-binding molecules with high affinity and base sequence specificity: intercalating agents covalently linked to oligodeoxynucleotides.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(11):3297-301.
1984: Ulysse Asseline; F Toulme; Nguyen T Thuong; M Delarue; T Montenay-Garestier; Claude Hélène
Oligodeoxynucleotides covalently linked to intercalating dyes as base sequence-specific ligands. Influence of dye attachment site.
The EMBO journal 1984;3(4):795-800.
1984: Jean-Jacques Toulmé; C Cazenave; M Chabbert; Claude Hélène
Binding of gene 32 protein from phage T4 and recA gene product from E. coli to fluorescent single-stranded polynucleotides.
Folia biologica 1984;30 Spec No():119-28.
1983: C Cazenave; Jean-Jacques Toulmé; Claude Hélène
Binding of RecA protein to single-stranded nucleic acids: spectroscopic studies using fluorescent polynucleotides.
The EMBO journal 1983;2(12):2247-51.
1981: Gérard Lancelot; R Mayer; Nguyen T Thuong; M Chassignol; Claude Hélène
Synthesis and structural studies of a self-complementary decadeoxynucleotide d(AATTGCAATT). II.-Proton magnetic resonance studies.
Biochimie 1981;63(10):785-90.
1981: Nguyen T Thuong; M Chassignol; Gérard Lancelot; R Mayer; B Hartmann; M Leng; Claude Hélène
Synthesis and structural studies of a self-complementary decadeoxynucleotide d(AATTGCAATT). I.-Synthesis and chemical characterization of the decanucleotide.
Biochimie 1981;63(10):775-84.