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Stuart Helfand

Research Profile

Living Beings

Dogs

Disorders

Anatomy

Tumor Cells, Cultured

Chemicals & Drugs

Procedures

Physiology

Cytotoxicity, Immunologic

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Publications

TOP 3
Erin B Dickerson; Brian J Druker; Wade Edris; Marc Loriaux; Valerie Macdonald; Kevin Marley; Vidya Schalk; Jeffrey W Tyner; Stuart C Helfand
Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.
Kevin Marley; John E Mata; Jan Medlock; Wade A Edris; Alix I Gitelman; Stuart C Helfand; Bernard Séguin
The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro.
Kevin Marley; Claudia S Maier; Stuart C Helfand
Phosphotyrosine enrichment identifies focal adhesion kinase and other tyrosine kinases for targeting in canine hemangiosarcoma.

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All Publications

2013: Erin B Dickerson; Brian J Druker; Wade Edris; Marc Loriaux; Valerie Macdonald; Kevin Marley; Vidya Schalk; Jeffrey W Tyner; Stuart C Helfand
Imatinib and Dasatinib Inhibit Hemangiosarcoma and Implicate PDGFR-β and Src in Tumor Growth.
Translational oncology 2013;6(2):158-68.
2013: Kevin Marley; John E Mata; Jan Medlock; Wade A Edris; Alix I Gitelman; Stuart C Helfand; Bernard Séguin
The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro.
BMC veterinary research 2013;9():15.
2012: Kevin Marley; Claudia S Maier; Stuart C Helfand
Phosphotyrosine enrichment identifies focal adhesion kinase and other tyrosine kinases for targeting in canine hemangiosarcoma.
Veterinary and comparative oncology 2012;10(3):214-22.
2009: S Shor; Stuart C Helfand; E Gorman; Christiane V Löhr
Diagnostic exercise: epithelioid hemangiosarcoma mimicking metastatic prostatic neoplasia in a dog.
Veterinary pathology 2009;46(3):548-52.
2007: Susan P Fosmire; R Thomas; Cristan M Jubala; John Wojcieszyn; V E O Valli; Dave Getzy; T L Smith; L A Gardner; Michelle G Ritt; J S Bell; K P Freeman; B E Greenfield; Susan E Lana; William C Kisseberth; Stuart C Helfand; Gary R Cutter; Matthew Breen; Jaime F Modiano
Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma.
Veterinary pathology 2007;44(4):467-78.
2006: Douglas Thamm; Erin B Dickerson; Nasim Akhtar; Rachel Lewis; Robert Auerbach; Stuart C Helfand; E Gregory MacEwen
Biological and molecular characterization of a canine hemangiosarcoma-derived cell line.
Research in veterinary science 2006;81(1):76-86.
2005: A E Hershey; R R Dubielzig; M L Padilla; Stuart C Helfand
Aberrant p53 expression in feline vaccine-associated sarcomas and correlation with prognosis.
Veterinary pathology 2005;42(6):805-11.
2005: Erin B Dickerson; R Thomas; Susan P Fosmire; A R Lamerato-Kozicki; Stacie R Bianco; John Wojcieszyn; Matthew Breen; Stuart C Helfand; Jaime F Modiano
Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.
Veterinary pathology 2005;42(5):618-32.
2004: Erin B Dickerson; Nasim Akhtar; Howard Steinberg; Zun-Yi Wang; Mary J Lindstrom; Marcia L Padilla; Robert Auerbach; Stuart C Helfand
Enhancement of the antiangiogenic activity of interleukin-12 by peptide targeted delivery of the cytokine to alphavbeta3 integrin.
Molecular cancer research : MCR 2004;2(12):663-73.
2004: Susan P Fosmire; Erin B Dickerson; Allyson M Scott; Stacie R Bianco; Marilyn J Pettengill; Heather Meylemans; Marcia L Padilla; Ashley A Frazer-Abel; Nasim Akhtar; Dave Getzy; John Wojcieszyn; Matthew Breen; Stuart C Helfand; Jaime F Modiano
Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium.
Laboratory investigation; a journal of technical methods and pathology 2004;84(5):562-72.
2004: Nasim Akhtar; Marcia L Padilla; Erin B Dickerson; Howard Steinberg; Matthew Breen; Robert Auerbach; Stuart C Helfand
Interleukin-12 inhibits tumor growth in a novel angiogenesis canine hemangiosarcoma xenograft model.
Neoplasia (New York, N.Y.) 2004;6(2):106-16.
2003: Stacie R Bianco; Juan Sun; Susan P Fosmire; Kenneth Hance; Marcia L Padilla; Michelle G Ritt; Dave Getzy; Richard C Duke; Stephen J Withrow; Susan E Lana; David T Matthiesen; Steven W Dow; Donald Bellgrau; Gary R Cutter; Stuart C Helfand; Jaime F Modiano
Enhancing antimelanoma immune responses through apoptosis.
Cancer gene therapy 2003;10(9):726-36.
2003: Michelle M Turek; Lisa J Forrest; William M Adams; Stuart C Helfand; David M Vail
Postoperative radiotherapy and mitoxantrone for anal sac adenocarcinoma in the dog: 15 cases (1991-2001).
Veterinary and comparative oncology 2003;1(2):94-104.
2002: Erin B Dickerson; Susan P Fosmire; Marcia L Padilla; Jaime F Modiano; Stuart C Helfand
Potential to target dysregulated interleukin-2 receptor expression in canine lymphoid and hematopoietic malignancies as a model for human cancer.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(1):36-45.
2000: Leslie E Fox; R C Rosenthal; R R King; P B Levine; David M Vail; Stuart C Helfand; E Gregory MacEwen; Roman Perez-Soler; M Calderwood-Mays; Ilene D Kurzman
Use of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II), a liposomal cisplatin analogue, in cats with oral squamous cell carcinoma.
American journal of veterinary research 2000;61(7):791-5.
1999: Brenda S Phillips; Marcia L Padilla; Erin B Dickerson; Mary J Lindstrom; Stuart C Helfand
Immunostimulatory effects of human recombinant interleukin-12 on peripheral blood mononuclear cells from normal dogs.
Veterinary immunology and immunopathology 1999;70(3-4):189-201.
1999: S A Soergel; E Gregory MacEwen; David M Vail; D M Potter; Paul M Sondel; Stuart C Helfand
The immunotherapeutic potential of activated canine alveolar macrophages and antitumor monoclonal antibodies in metastatic canine melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 1999;22(5):443-53.
1999: Stuart C Helfand; Erin B Dickerson; K L Munson; Marcia L Padilla
GD3 ganglioside antibody augments tumoricidal capacity of canine blood mononuclear cells by induction of interleukin 12.
Cancer research 1999;59(13):3119-27.
1996: CA London; W C Kisseberth; Stephen J Galli; E N Geissler; Stuart C Helfand
Expression of stem cell factor receptor (c-kit) by the malignant mast cells from spontaneous canine mast cell tumours.
Journal of comparative pathology 1996;115(4):399-414.
1996: Stuart C Helfand; Jacquelyn A Hank; Jacek Gan; Paul M Sondel
Lysis of human tumor cell lines by canine complement plus monoclonal antiganglioside antibodies or natural canine xenoantibodies.
Cellular immunology 1996;167(1):99-107.
1995: Ilene D Kurzman; E Gregory MacEwen; R C Rosenthal; Leslie E Fox; Evan T Keller; Stuart C Helfand; David M Vail; Richard R Dubielzig; Bruce R Madewell; C O Rodriguez
Adjuvant therapy for osteosarcoma in dogs: results of randomized clinical trials using combined liposome-encapsulated muramyl tripeptide and cisplatin.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1595-601.
1995: W C Kisseberth; E Gregory MacEwen; Stuart C Helfand; David M Vail; C L London; Evan T Keller
Response to liposome-encapsulated doxorubicin (TLC D-99) in a dog with myeloma.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1995;9(6):425-8.
1995: David M Vail; E Gregory MacEwen; Ilene D Kurzman; Richard R Dubielzig; Stuart C Helfand; W C Kisseberth; CA London; J E Obradovich; Bruce R Madewell; C O Rodriguez
Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine adjuvant immunotherapy for splenic hemangiosarcoma in the dog: a randomized multi-institutional clinical trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(10):1165-70.
1995: Stuart C Helfand; Jaime F Modiano; Peter F Moore; S A Soergel; PS MacWilliams; R D Dubielzig; Jacquelyn A Hank; E W Gelfand; Paul M Sondel
Functional interleukin-2 receptors are expressed on natural killer-like leukemic cells from a dog with cutaneous lymphoma.
Blood 1995;86(2):636-45.
1995: D L Panciera; Stuart C Helfand; S A Soergel
Acute effects of continuous infusions of human recombinant interleukin-2 on serum thyroid hormone concentrations in dogs.
Research in veterinary science 1995;58(1):96-7.
1995: Leslie E Fox; E Gregory MacEwen; Ilene D Kurzman; Richard R Dubielzig; Stuart C Helfand; David M Vail; W Kisseberth; C London; Bruce R Madewell; C O Rodriguez
Liposome-encapsulated muramyl tripeptide phosphatidylethanolamine for the treatment of feline mammary adenocarcinoma--a multicenter randomized double-blind study.
Cancer biotherapy 1995;10(2):125-30.
1994: Stuart C Helfand; S A Soergel; R L Donner; Jacek Gan; Jacquelyn A Hank; Mary J Lindstrom; Paul M Sondel
Potential to involve multiple effector cells with human recombinant interleukin-2 and antiganglioside monoclonal antibodies in a canine malignant melanoma immunotherapy model.
Journal of immunotherapy with emphasis on tumor immunology : official journal of the Society for Biological Therapy 1994;16(3):188-97.
1994: Stuart C Helfand; S A Soergel; PS MacWilliams; Jacquelyn A Hank; Paul M Sondel
Clinical and immunological effects of human recombinant interleukin-2 given by repetitive weekly infusion to normal dogs.
Cancer immunology, immunotherapy : CII 1994;39(2):84-92.
1994: Stuart C Helfand; S A Soergel; Jaime F Modiano; Jacquelyn A Hank; Paul M Sondel
Induction of lymphokine-activated killer (LAK) activity in canine lymphocytes with low dose human recombinant interleukin-2 in vitro.
Cancer biotherapy 1994;9(3):237-44.
1994: E Gregory MacEwen; Ilene D Kurzman; Stuart C Helfand; David M Vail; C London; W Kisseberth; R C Rosenthal; Leslie E Fox; Evan T Keller; J Obradovich
Current studies of liposome muramyl tripeptide (CGP 19835A lipid) therapy for metastasis in spontaneous tumors: a progress review.
Journal of drug targeting 1994;2(5):391-6.
1993: Evan T Keller; E Gregory MacEwen; R C Rosenthal; Stuart C Helfand; Leslie E Fox
Evaluation of prognostic factors and sequential combination chemotherapy with doxorubicin for canine lymphoma.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 1993;7(5):289-95.
1992: Stuart C Helfand; Jaime F Modiano; P C Nowell
Immunophysiological studies of interleukin-2 and canine lymphocytes.
Veterinary immunology and immunopathology 1992;33(1-2):1-16.