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William Helferich
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16
Ju, Young
11
Doerge, Daniel
10
Allred, Clinton
10
Allred, Kimberly
5
Grant, AL
4
Aulerich, Richard
4
Bursian, Steven
4
Cooke, Paul
4
Katzenellenbogen, John
4
Shipp, Elizabeth
3
Yellayi, Srikanth
3
Zakroczymski, Melissa
3
Santell, RC
3
Naaz, Afia
3
Katzenellenbogen, Benita
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Geonetwork of William Helferich (preview)
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All Publications
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2009: Legette Leecole L; Martin Berdine R; Shahnazari Mohammad; Lee Wang-Hee; Helferich William G; Qian Junqi; Waters David J; Arabshahi Alireza; Barnes Stephen; Welch Jo; Bostwick David G; Weaver Connie M
Supplemental dietary racemic equol has modest benefits to bone but has mild uterotropic activity in ovariectomized rats.
The Journal of nutrition 2009;139(10):1908-13.
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2008: Jiang Xinguo; Patterson Nicole M; Ling Yan; Xie Jianwei; Helferich William G; Shapiro David J
Low concentrations of the soy phytoestrogen genistein induce proteinase inhibitor 9 and block killing of breast cancer cells by immune cells.
Endocrinology 2008;149(11):5366-73.
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2008: Ju Young H; Doerge Daniel R; Woodling Kellie A; Hartman James A; Kwak Jieun; Helferich William G
Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo.
Carcinogenesis 2008;29(11):2162-8.
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2008: Wang Victor C; Sable Helen J K; Ju Young H; Allred Clinton D; Helferich William G; Korol Donna L; Schantz Susan L
Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding.
Behavioral neuroscience 2008;122(4):794-804.
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2008: Chang Edmund C; Charn Tze Howe; Park Sung-Hee; Helferich William G; Komm Barry; Katzenellenbogen John A; Katzenellenbogen Benita S
Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding.
Molecular endocrinology (Baltimore, Md.) 2008;22(5):1032-43.
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2008: Ju Young H; Doerge Daniel R; Helferich William G
A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2008;46(1):310-20.
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2006: Heemstra Jennifer M; Kerrigan Sean A; Doerge Daniel R; Helferich William G; Boulanger William A
Total synthesis of (S)-equol.
Organic letters 2006;8(24):5441-3.
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2006: Putt Karson S; Chen Grace W; Pearson Jennifer M; Sandhorst Joseph S; Hoagland Martin S; Kwon Jung-Taek; Hwang Soon-Kyung; Jin Hua; Churchwell Mona I; Cho Myung-Haing; Doerge Daniel R; Helferich William G; Hergenrother Paul J
Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.
Nature chemical biology 2006;2(10):543-50.
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2006: Ju Young H; Allred Kimberly F; Allred Clinton D; Helferich William G
Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations.
Carcinogenesis 2006;27(6):1292-9.
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2006: Ju Young H; Fultz Jodi; Allred Kimberly F; Doerge Daniel R; Helferich William G
Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice.
Carcinogenesis 2006;27(4):856-63.
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2005: Allred Clinton D; Twaddle Nathan C; Allred Kimberly F; Goeppinger Tracy S; Churchwell Mona I; Ju Young H; Helferich William G; Doerge Daniel R
Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized BALB/c mice.
Journal of agricultural and food chemistry 2005;53(22):8542-50.
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2004: Selvaraj Vimal; Zakroczymski Melissa A; Naaz Afia; Mukai Motoko; Ju Young H; Doerge Daniel R; Katzenellenbogen John A; Helferich William G; Cooke Paul S
Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice.
Biology of reproduction 2004;71(3):966-72.
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2004: Allred Clinton D; Allred Kimberly F; Ju Young H; Goeppinger Tracy S; Doerge Daniel R; Helferich William G
Soy processing influences growth of estrogen-dependent breast cancer tumors.
Carcinogenesis 2004;25(9):1649-57.
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2004: Ju Young H; Clausen Laura M; Allred Kimberly F; Almada Anthony L; Helferich William G
beta-Sitosterol, beta-Sitosterol Glucoside, and a Mixture of beta-Sitosterol and beta-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice.
The Journal of nutrition 2004;134(5):1145-51.
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2004: Muthyala Rajeev S; Ju Young H; Sheng Shubin; Williams Lee D; Doerge Daniel R; Katzenellenbogen Benita S; Helferich William G; Katzenellenbogen John A
Equol, a natural estrogenic metabolite from soy isoflavones: convenient preparation and resolution of R- and S-equols and their differing binding and biological activity through estrogen receptors alpha and beta.
Bioorganic & medicinal chemistry 2004;12(6):1559-67.
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2004: Allred Clinton D; Allred Kimberly F; Ju Young H; Clausen Laura M; Doerge Daniel R; Schantz Susan L; Korol Donna L; Wallig Matthew A; Helferich William G
Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats.
Carcinogenesis 2004;25(2):211-8.
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2003: Naaz Afia; Yellayi Srikanth; Zakroczymski Melissa A; Bunick David; Doerge Daniel R; Lubahn Dennis B; Helferich William G; Cooke Paul S
The soy isoflavone genistein decreases adipose deposition in mice.
Endocrinology 2003;144(8):3315-20.
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2003: Yellayi S; Zakroczymski M A; Selvaraj V; Valli V E; V Ghanta; Helferich W G; Cooke P S
The phytoestrogen genistein suppresses cell-mediated immunity in mice.
The Journal of endocrinology 2003;176(2):267-74.
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2002: Yellayi Srikanth; Naaz Afia; Szewczykowski Melissa A; Sato Tomomi; Woods Jeffrey A; Chang Jongsoo; Segre Mariangela; Allred Clint D; Helferich William G; Cooke Paul S
The phytoestrogen genistein induces thymic and immune changes: a human health concern?
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7616-21.
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2002: Ju Young H; Doerge Daniel R; Allred Kimberly F; Allred Clinton D; Helferich William G
Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice.
Cancer research 2002;62(9):2474-7.
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2001: Ju Y H; Allred C D; Allred K F; Karko K L; Doerge D R; Helferich W G
Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice.
The Journal of nutrition 2001;131(11):2957-62.
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2001: Allred C D; Ju Y H; Allred K F; Chang J; Helferich W G
Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with genistein.
Carcinogenesis 2001;22(10):1667-73.
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2001: Allred C D; Allred K F; Ju Y H; Virant S M; Helferich W G
Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner.
Cancer research 2001;61(13):5045-50.
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2000: Ju Y H; Carlson K E; Sun J; Pathak D; Katzenellenbogen B S; Katzenellenbogen J A; Helferich W G
Estrogenic effects of extracts from cabbage, fermented cabbage, and acidified brussels sprouts on growth and gene expression of estrogen-dependent human breast cancer (MCF-7) cells.
Journal of agricultural and food chemistry 2000;48(10):4628-34.
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2000: Santell R C; Kieu N; Helferich W G
Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice.
The Journal of nutrition 2000;130(7):1665-9.
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1998: Hsieh C Y; Santell R C; Haslam S Z; Helferich W G
Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo.
Cancer research 1998;58(17):3833-8.
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1998: Shipp E B; Restum J C; Bursian S J; Aulerich R J; Helferich W G
Multigenerational study of the effects of consumption of PCB-contaminated carp from Saginaw Bay, Lake Huron, on mink. 3. Estrogen receptor and progesterone receptor concentrations, and potential correlation with dietary PCB consumption.
Journal of toxicology and environmental health. Part A 1998;54(5):403-20.
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1998: Shipp E B; Restum J C; Giesy J P; Bursian S J; Aulerich R J; Helferich W G
Multigenerational study of the effects of consumption of PCB-contaminated carp from Saginaw Bay, Lake Huron, on mink. 2. Liver PCB concentration and induction of hepatic cytochrome P-450 activity as a potential biomarker for PCB exposure.
Journal of toxicology and environmental health. Part A 1998;54(5):377-401.
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1998: Restum J C; Bursian S J; Giesy J P; Render J A; Helferich W G; Shipp E B; Verbrugge D A; Aulerich R J
Multigenerational study of the effects of consumption of PCB-contaminated carp from Saginaw Bay, Lake Huron, on mink. 1. Effects on mink reproduction, kit growth and survival, and selected biological parameters.
Journal of toxicology and environmental health. Part A 1998;54(5):343-75.
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1997: Kramer V J; Helferich W G; Bergman A; Klasson-Wehler E; Giesy J P
Hydroxylated polychlorinated biphenyl metabolites are anti-estrogenic in a stably transfected human breast adenocarcinoma (MCF7) cell line.
Toxicology and applied pharmacology 1997;144(2):363-76.
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1997: Kustasz R; Helferich W; Adams T; Krier J
A unique myosin isoform transition in cat striated external anal sphincter muscle induced by denervation.
The American journal of physiology 1997;272(4 Pt 1):G698-704.
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1997: Santell R C; Chang Y C; Nair M G; Helferich W G
Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats.
The Journal of nutrition 1997;127(2):263-9.
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1995: Yang H H; Aulerich R J; Helferich W; Yamini B; Chou K C; Miller E R; Bursian S J
Effects of zearalenone and/or tamoxifen on swine and mink reproduction.
Journal of applied toxicology : JAT 1995;15(3):223-32.
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1994: Mistry A M; Helferich W; Romsos D R
Elevated neuronal c-Fos-like immunoreactivity and messenger ribonucleic acid (mRNA) in genetically obese (ob/ob) mice.
Brain research 1994;666(1):53-60.
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1994: Shipp E B; Mehigh C S; Helferich W G
The effect of colupulone (a HOPS beta-acid) on hepatic cytochrome P-450 enzymatic activity in the rat.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(11):1007-14.
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1994: Chang C H; Grant A L; Strasburg G M; Bergen W G; Merkel R A; Helferich W G
RNA transcription in porcine skeletal muscle nuclei during postnatal development.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1994;206(2):162-8.
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1993: Grant A L; Skjaerlund D M; Helferich W G; Bergen W G; Merkel R A
Skeletal muscle growth and expression of skeletal muscle alpha-actin mRNA and insulin-like growth factor I mRNA in pigs during feeding and withdrawal of ractopamine.
Journal of animal science 1993;71(12):3319-26.
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1993: Mehigh C S; Elias V D; Mehigh R J; Helferich W G; Tucker H A
Development of a recombinant bovine leukemia virus vector for delivery of a synthetic bovine growth hormone-releasing factor gene into bovine cells.
Journal of animal science 1993;71(3):687-93.
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1993: Skjaerlund D M; Grant A L; Helferich W G; Bergen W G; Merkel R A
Determination of the relative abundance of skeletal muscle alpha actin mRNA in muscle of livestock species.
Journal of animal science 1993;71(2):393-9.
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1991: Helferich W G; Denison M S
Ultraviolet photoproducts of tryptophan can act as dioxin agonists.
Molecular pharmacology 1991;40(5):674-8.
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1991: Grant A L; Helferich W G; Kramer S A; Merkel R A; Bergen W G
Administration of growth hormone to pigs alters the relative amount of insulin-like growth factor-I mRNA in liver and skeletal muscle.
The Journal of endocrinology 1991;130(3):331-8.
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1990: Anderson P T; Helferich W G; Parkhill L C; Merkel R A; Bergen W G
Ractopamine increases total and myofibrillar protein synthesis in cultured rat myotubes.
The Journal of nutrition 1990;120(12):1677-83.
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1990: Helferich W G; Jump D B; Anderson D B; Skjaerlund D M; Merkel R A; Bergen W G
Skeletal muscle alpha-actin synthesis is increased pretranslationally in pigs fed the phenethanolamine ractopamine.
Endocrinology 1990;126(6):3096-100.
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1990: Grant A L; Helferich W G; Merkel R A; Bergen W G
Effects of phenethanolamines and propranolol on the proliferation of cultured chick breast muscle satellite cells.
Journal of animal science 1990;68(3):652-8.
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