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Cheryl Helgason

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Brad G Hoffman; Gordon Robertson; Bogard Zavaglia; Mike Beach; Rebecca Cullum; Sam Lee; Galina Soukhatcheva; Leping Li; Elizabeth D Wederell; Nina Thiessen; Mikhail Bilenky; Timothee Cezard; Angela Tam; Baljit Kamoh; Inanc Birol; Derek Dai; Yongjun Zhao; Martin Hirst; C Bruce Verchere; Cheryl D Helgason; Marco A Marra; Steven J M Jones; Pamela A Hoodless
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.
Cynthia L Fisher; Nicolas Pineault; Christy Brookes; Cheryl D Helgason; Hideaki Ohta; Caroline Bodner; Jay L Hess; R Keith Humphries; Hugh W Brock
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.
Peter T W Kim; Brad G Hoffman; Annette Plesner; Cheryl D Helgason; C Bruce Verchere; Stephen W Chung; Garth L Warnock; Alice L-F Mui; Christopher J Ong
Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation.

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All Publications

2010: Brad G Hoffman; Gordon Robertson; Bogard Zavaglia; Mike Beach; Rebecca Cullum; Sam Lee; Galina Soukhatcheva; Leping Li; Elizabeth D Wederell; Nina Thiessen; Mikhail Bilenky; Timothee Cezard; Angela Tam; Baljit Kamoh; Inanc Birol; Derek Dai; Yongjun Zhao; Martin Hirst; C Bruce Verchere; Cheryl D Helgason; Marco A Marra; Steven J M Jones; Pamela A Hoodless
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver.
Genome research 2010;20(8):1037-51.
2010: Cynthia L Fisher; Nicolas Pineault; Christy Brookes; Cheryl D Helgason; Hideaki Ohta; Caroline Bodner; Jay L Hess; R Keith Humphries; Hugh W Brock
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.
Blood 2010;115(1):38-46.
2010: Peter T W Kim; Brad G Hoffman; Annette Plesner; Cheryl D Helgason; C Bruce Verchere; Stephen W Chung; Garth L Warnock; Alice L-F Mui; Christopher J Ong
Differentiation of mouse embryonic stem cells into endoderm without embryoid body formation.
PloS one 2010;5(11):e14146.
2007: Min Lu; Clive H Glover; Amy H Tien; R Keith Humphries; James M Piret; Cheryl D Helgason
Involvement of tyrosine kinase signaling in maintaining murine embryonic stem cell functionality.
Experimental hematology 2007;35(8):1293-302.
2007: Leanne Neill; Amy H Tien; Jose Rey-Ladino; Cheryl D Helgason
SHIP-deficient mice provide insights into the regulation of dendritic cell development and function.
Experimental hematology 2007;35(4):627-39.
2006: Clive H Glover; Michael Marin; Connie J Eaves; Cheryl D Helgason; James M Piret; Jennifer Bryan
Meta-analysis of differentiating mouse embryonic stem cell gene expression kinetics reveals early change of a small gene set.
PLoS computational biology 2006;2(11):e158.
2006: Tian-Jiao Zhang; Brad G Hoffman; Teresa Ruiz de Algara; Cheryl D Helgason
SAGE reveals expression of Wnt signalling pathway members during mouse prostate development.
Gene expression patterns : GEP 2006;6(3):310-24.
2006: B G Hoffman; K L Williams; Amy H Tien; V Lu; T Ruiz de Algara; J P-Y Ting; Cheryl D Helgason
Identification of novel genes and transcription factors involved in spleen, thymus and immunological development and function.
Genes and immunity 2006;7(2):101-12.
2005: Lars Palmqvist; Clive H Glover; Lien Hsu; Min Lu; Bolette Bossen; James M Piret; R Keith Humphries; Cheryl D Helgason
Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency.
Stem cells (Dayton, Ohio) 2005;23(5):663-80.
2005: Amy H Tien; Lixin Xu; Cheryl D Helgason
Altered immunity accompanies disease progression in a mouse model of prostate dysplasia.
Cancer research 2005;65(7):2947-55.
2005: Cheryl D Helgason
Culture of primary adherent cells and a continuously growing nonadherent cell line.
Methods in molecular biology (Clifton, N.J.) 2005;290():1-12.
2003: Cheryl D Helgason; Jennifer Antonchuk; Caroline Bodner; R Keith Humphries
Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice.
Blood 2003;102(10):3541-7.
2002: Sunao Takeshita; Noriyuki Namba; Jenny J Zhao; Yebin Jiang; Harry K Genant; Matthew J Silva; Michael D Brodt; Cheryl D Helgason; Janet Kalesnikoff; Michael J Rauh; R Keith Humphries; Gerald Krystal; Steven L Teitelbaum; F Patrick Ross
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts.
Nature medicine 2002;8(9):943-9.
2002: Nicolas Pineault; Cheryl D Helgason; H Jeffrey Lawrence; R Keith Humphries
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny.
Experimental hematology 2002;30(1):49-57.
2000: Cheryl D Helgason; Christian Kalberer; Jacqueline E Damen; S M Chappel; Nicolas Pineault; Gerald Krystal; R Keith Humphries
A dual role for Src homology 2 domain-containing inositol-5-phosphatase (SHIP) in immunity: aberrant development and enhanced function of b lymphocytes in ship -/- mice.
The Journal of experimental medicine 2000;191(5):781-94.
2000: Martina Metzler; Cheryl D Helgason; Ioannis Dragatsis; T Zhang; Lu Gan; Nicolas Pineault; Scott Zeitlin; R Keith Humphries; Michael R Hayden
Huntingtin is required for normal hematopoiesis.
Human molecular genetics 2000;9(3):387-94.
1999: Gerald Krystal; Jacqueline E Damen; Cheryl D Helgason; Michael Huber; Michael R. Hughes; Janet Kalesnikoff; Vivian Lam; Patricia M Rosten; MD Ware; S Yew; R Keith Humphries
SHIPs ahoy.
The international journal of biochemistry & cell biology 1999;31(10):1007-10.
1999: Michael Huber; Cheryl D Helgason; Jacqueline E Damen; Michael P Scheid; Vincent Duronio; Vivian Lam; R Keith Humphries; Gerald Krystal
The role of the SRC homology 2-containing inositol 5'-phosphatase in Fc epsilon R1-induced signaling.
Current topics in microbiology and immunology 1999;244():29-41.
1999: Michael Huber; Cheryl D Helgason; Jacqueline E Damen; Michael P Scheid; Vincent Duronio; L Liu; MD Ware; R Keith Humphries; Gerald Krystal
The role of SHIP in growth factor induced signalling.
Progress in biophysics and molecular biology 1999;71(3-4):423-34.
1998: Michael Huber; Cheryl D Helgason; Michael P Scheid; Vincent Duronio; R Keith Humphries; Gerald Krystal
Targeted disruption of SHIP leads to Steel factor-induced degranulation of mast cells.
The EMBO journal 1998;17(24):7311-9.
1998: Michael Huber; Cheryl D Helgason; Jacqueline E Damen; Lidong Liu; R Keith Humphries; Gerald Krystal
The src homology 2-containing inositol phosphatase (SHIP) is the gatekeeper of mast cell degranulation.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11330-5.
1998: Cheryl D Helgason; Jacqueline E Damen; Patricia M Rosten; R Grewal; P Sorensen; S M Chappel; A Borowski; Frank R Jirik; Gerald Krystal; R Keith Humphries
Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span.
Genes & development 1998;12(11):1610-20.
1997: H Jeffrey Lawrence; Cheryl D Helgason; Guy Sauvageau; Sylvia Fong; D J Izon; R Keith Humphries; Corey Largman
Mice bearing a targeted interruption of the homeobox gene HOXA9 have defects in myeloid, erythroid, and lymphoid hematopoiesis.
Blood 1997;89(6):1922-30.
1997: C L Miller; Vivienne Rebel; Cheryl D Helgason; Peter M Lansdorp; Connie J Eaves
Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo.
Blood 1997;89(4):1214-23.
1996: C L Miller; Vivienne Rebel; M E Lemieux; Cheryl D Helgason; Peter M Lansdorp; C J Eaves
Studies of W mutant mice provide evidence for alternate mechanisms capable of activating hematopoietic stem cells.
Experimental hematology 1996;24(2):185-94.