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Rosalind Hembry

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

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Immunohistochemistry

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Fluorescent Antibody Technique

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Co-Publications
Name
24
Reynolds, John
13
Murphy, Gillian
8
Meikle, Murray
7
Bord, Sharyn
6
Atkinson, Susan
6
Stanton, Heather
5
Compston, Juliet
4
Fosang, Amanda
4
Horner, A
3
Knäuper, Vera
3
d'Ortho, Marie-Pia
2
Cowell, S
2
Last, Karena
2
López-Otín, Carlos
2
Shuttleworth, Adrian

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Publications

TOP 3
Hembry Rosalind M; Atkinson Susan J; Murphy Gillian
Assessment of gelatinase expression and activity in articular cartilage.
Little Christopher B; Meeker Clare T; Hembry Rosalind M; Sims Natalie A; Lawlor Kate E; Golub Sue B; Last Karena; Fosang Amanda J
Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development.
Hembry R M; Dyce J; Driesang I; Hunziker E B; Fosang A J; Tyler J A; Murphy G
Immunolocalization of matrix metalloproteinases in partial-thickness defects in pig articular cartilage. A preliminary report.

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All Publications

2007: Hembry Rosalind M; Atkinson Susan J; Murphy Gillian
Assessment of gelatinase expression and activity in articular cartilage.
Methods in molecular medicine 2007;135():227-38.
2005: Little Christopher B; Meeker Clare T; Hembry Rosalind M; Sims Natalie A; Lawlor Kate E; Golub Sue B; Last Karena; Fosang Amanda J
Matrix metalloproteinases are not essential for aggrecan turnover during normal skeletal growth and development.
Molecular and cellular biology 2005;25(8):3388-99.
2001: Hembry R M; Dyce J; Driesang I; Hunziker E B; Fosang A J; Tyler J A; Murphy G
Immunolocalization of matrix metalloproteinases in partial-thickness defects in pig articular cartilage. A preliminary report.
The Journal of bone and joint surgery. American volume 2001;83-A(6):826-38.
2001: Hembry R M
Detection of focal proteolysis using Texas-red-gelatin.
Methods in molecular biology (Clifton, N.J.) 2001;151():417-24.
2000: Fosang A J; Last K; Stanton H; Weeks D B; Campbell I K; Hardingham T E; Hembry R M
Generation and novel distribution of matrix metalloproteinase-derived aggrecan fragments in porcine cartilage explants.
The Journal of biological chemistry 2000;275(42):33027-37.
2000: Dew G; Murphy G; Stanton H; Vallon R; Angel P; Reynolds J J; Hembry R M
Localisation of matrix metalloproteinases and TIMP-2 in resorbing mouse bone.
Cell and tissue research 2000;299(3):385-94.
1999: Breckon J J; Papaioannou S; Kon L W; Tumber A; Hembry R M; Murphy G; Reynolds J J; Meikle M C
Stromelysin (MMP-3) synthesis is up-regulated in estrogen-deficient mouse osteoblasts in vivo and in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(11):1880-90.
1999: Préaux A M; Mallat A; Nhieu J T; D'Ortho M P; Hembry R M; Mavier P
Matrix metalloproteinase-2 activation in human hepatic fibrosis regulation by cell-matrix interactions.
Hepatology (Baltimore, Md.) 1999;30(4):944-50.
1999: Murphy G; Knäuper V; Cowell S; Hembry R; Stanton H; Butler G; Freije J; Pendás A M; López-Otín C
Evaluation of some newer matrix metalloproteinases.
Annals of the New York Academy of Sciences 1999;878():25-39.
1999: Bord S; Horner A; Beeton C A; Hembry R M; Compston J E
Tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) distribution in normal and pathological human bone.
Bone 1999;24(3):229-35.
1998: Bord S; Horner A; Hembry R M; Compston J E
Stromelysin-1 (MMP-3) and stromelysin-2 (MMP-10) expression in developing human bone: potential roles in skeletal development.
Bone 1998;23(1):7-12.
1998: Cowell S; Knäuper V; Stewart M L; D'Ortho M P; Stanton H; Hembry R M; López-Otín C; Reynolds J J; Murphy G
Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3.
The Biochemical journal 1998;331 ( Pt 2)():453-8.
1998: d'Ortho M P; Stanton H; Butler M; Atkinson S J; Murphy G; Hembry R M
MT1-MMP on the cell surface causes focal degradation of gelatin films.
FEBS letters 1998;421(2):159-64.
1997: Bord S; Horner A; Hembry R M; Reynolds J J; Compston J E
Distribution of matrix metalloproteinases and their inhibitor, TIMP-1, in developing human osteophytic bone.
Journal of anatomy 1997;191 ( Pt 1)():39-48.
1996: Bord S; Horner A; Hembry R M; Reynolds J J; Compston J E
Production of collagenase by human osteoblasts and osteoclasts in vivo.
Bone 1996;19(1):35-40.
1996: Knäuper V; Will H; López-Otin C; Smith B; Atkinson S J; Stanton H; Hembry R M; Murphy G
Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme.
The Journal of biological chemistry 1996;271(29):17124-31.
1995: Meikle M C; Bord S; Hembry R M; Reynolds J J
The synthesis of collagenase, gelatinase-A (72 kDa) and -B (95 kDa), and TIMP-1 and -2 by human osteoblasts from normal and arthritic bone.
Bone 1995;17(3):255-60.
1995: Hembry R M; Bagga M R; Reynolds J J; Hamblen D L
Stromelysin, gelatinase A and TIMP-1 in prosthetic interface tissue: a role for macrophages in tissue remodelling.
Histopathology 1995;27(2):149-59.
1995: Hembry R M; Bagga M R; Reynolds J J; Hamblen D L
Immunolocalisation studies on six matrix metalloproteinases and their inhibitors, TIMP-1 and TIMP-2, in synovia from patients with osteo- and rheumatoid arthritis.
Annals of the rheumatic diseases 1995;54(1):25-32.
1994: Hill P A; Murphy G; Docherty A J; Hembry R M; Millican T A; Reynolds J J; Meikle M C
The effects of selective inhibitors of matrix metalloproteinases (MMPs) on bone resorption and the identification of MMPs and TIMP-1 in isolated osteoclasts.
Journal of cell science 1994;107 ( Pt 11)():3055-64.
1994: Meikle M C; Bord S; Hembry R M; Reynolds J J
Rabbit calvarial osteoblasts in culture constitutively synthesize progelatinase-A, and TIMP-1 and TIMP-2.
Biochimica et biophysica acta 1994;1224(1):99-102.
1994: Bailey C J; Hembry R M; Alexander A; Irving M H; Grant M E; Shuttleworth C A
Distribution of the matrix metalloproteinases stromelysin, gelatinases A and B, and collagenase in Crohn's disease and normal intestine.
Journal of clinical pathology 1994;47(2):113-6.
1994: Hembry R M; Bagga M R; Dingle J T; Thomas P P; Reynolds J J
Metalloproteinase production by rabbit articular cartilage: comparison of the effects of interleukin-1 alpha in vitro and in vivo.
Virchows Archiv : an international journal of pathology 1994;425(4):413-24.
1993: Hembry R M; Bagga M R; Murphy G; Henderson B; Reynolds J J
Rabbit models of arthritis: immunolocalization of matrix metalloproteinases and tissue inhibitor of metalloproteinase in synovium and cartilage.
The American journal of pathology 1993;143(2):628-42.
1992: Meikle M C; Bord S; Hembry R M; Compston J; Croucher P I; Reynolds J J
Human osteoblasts in culture synthesize collagenase and other matrix metalloproteinases in response to osteotropic hormones and cytokines.
Journal of cell science 1992;103 ( Pt 4)():1093-9.
1992: Murphy G; Hembry R M
Proteinases in rheumatoid arthritis.
The Journal of rheumatology. Supplement 1992;32():61-4.
1992: Reynolds J J; Hembry R M
Immunolocalization of metalloproteinases and TIMP in normal and pathological tissues.
Matrix (Stuttgart, Germany). Supplement 1992;1():375-82.
1991: Ward R V; Hembry R M; Reynolds J J; Murphy G
The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.
The Biochemical journal 1991;278 ( Pt 1)():179-87.
1990: Bailey C J; Hembry R M; Alexander A; Shuttleworth C A; Grant M E; Irving M L
Metalloproteinases in the intestine of patients with Crohn's disease.
Biochemical Society transactions 1990;18(5):896-7.
1990: Murphy G; Hembry R M; Hughes C E; Fosang A J; Hardingham T E
Role and regulation of metalloproteinases in connective tissue turnover.
Biochemical Society transactions 1990;18(5):812-5.
1990: Green D D; Hembry R M; Atkinson S J; Reynolds J J; Meikle M C
Immunolocalization of collagenase and tissue inhibitor of metalloproteinases (TIMP) in mechanically deformed fibrous joints.
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 1990;97(4):281-8.
1989: Thomson B M; Atkinson S J; McGarrity A M; Hembry R M; Reynolds J J; Meikle M C
Type I collagen degradation by mouse calvarial osteoblasts stimulated with 1,25-dihydroxyvitamin D-3: evidence for a plasminogen-plasmin-metalloproteinase activation cascade.
Biochimica et biophysica acta 1989;1014(2):125-32.
1989: Gavrilovic J; Hembry R M; Reynolds J J; Murphy G
Collagenase is expressed by rabbit VX2 tumour cells in syngeneic and xenogeneic hosts.
Matrix (Stuttgart, Germany) 1989;9(3):206-13.
1989: Brown C C; Hembry R M; Reynolds J J
Immunolocalization of metalloproteinases and their inhibitor in the rabbit growth plate.
The Journal of bone and joint surgery. American volume 1989;71(4):580-93.
1989: Murphy G; Hembry R M; McGarrity A M; Reynolds J J; Henderson B
Gelatinase (type IV collagenase) immunolocalization in cells and tissues: use of an antiserum to rabbit bone gelatinase that identifies high and low Mr forms.
Journal of cell science 1989;92 ( Pt 3)():487-95.
1989: Fell H B; Lawrence C E; Bagga M R; Hembry R M; Reynolds J J
The degradation of collagen in pig synovium in vitro and the effect of colchicine.
Matrix (Stuttgart, Germany) 1989;9(2):116-26.
1989: Murphy G; Ward R; Hembry R M; Reynolds J J; Kühn K; Tryggvason K
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.
The Biochemical journal 1989;258(2):463-72.
1987: Heath J K; Atkinson S J; Hembry R M; Reynolds J J; Meikle M C
Bacterial antigens induce collagenase and prostaglandin E2 synthesis in human gingival fibroblasts through a primary effect on circulating mononuclear cells.
Infection and immunity 1987;55(9):2148-54.
1987: Gavrilovic J; Hembry R M; Reynolds J J; Murphy G
Tissue inhibitor of metalloproteinases (TIMP) regulates extracellular type I collagen degradation by chondrocytes and endothelial cells.
Journal of cell science 1987;87 ( Pt 2)():357-62.
1986: Hembry R M; Murphy G; Cawston T E; Dingle J T; Reynolds J J
Characterization of a specific antiserum for mammalian collagenase from several species: immunolocalization of collagenase in rabbit chondrocytes and uterus.
Journal of cell science 1986;81():105-23.
1982: Hembry R M; Knight C G; Dingle J T; Barrett A J
Evidence that extracellular cathepsin D is not responsible for the resorption of cartilage matrix in culture.
Biochimica et biophysica acta 1982;714(2):307-12.
1980: Knight C G; Hornebeck W; Matthews I T; Hembry R M; Dingle J T
Interaction of dinitrophenyl-pepstatins with human cathepsin D and with anti-dinitrophenyl antibody. Development of potential reagents for the localization in vivo of active proteinases at sites of tissue injury.
The Biochemical journal 1980;191(3):835-43.

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