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Ute Hempel

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Cornelia Wolf-Brandstetter; Sandra Storch; Susanne Bierbaum; Uwe Gbureck; Ute Hempel; Berthold Nies; Sophie Roessler; Dieter Scharnweber
Physicochemical and cell biological characterization of PMMA bone cements modified with additives to increase bioactivity.
Marianne Büttner; Peter Dieter; Daniel Huster; Mario Keller; Stephanie Möller; Jürgen Schiller; Matthias Schnabelrauch; Ute Hempel
Over-sulfated chondroitin sulfate derivatives induce osteogenic differentiation of hMSC independent of BMP-2 and TGF-β1 signalling.
Ute Hempel; Peter Dieter; Thomas Hefti; Falko Schlottig
Response of human bone marrow stromal cells, MG-63, and SaOS-2 to titanium-based dental implant surfaces with different topography and surface energy.

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All Publications

2013: Cornelia Wolf-Brandstetter; Sandra Storch; Susanne Bierbaum; Uwe Gbureck; Ute Hempel; Berthold Nies; Sophie Roessler; Dieter Scharnweber
Physicochemical and cell biological characterization of PMMA bone cements modified with additives to increase bioactivity.
Journal of biomedical materials research. Part B, Applied biomaterials 2013;101(4):599-609.
2013: Marianne Büttner; Peter Dieter; Daniel Huster; Mario Keller; Stephanie Möller; Jürgen Schiller; Matthias Schnabelrauch; Ute Hempel
Over-sulfated chondroitin sulfate derivatives induce osteogenic differentiation of hMSC independent of BMP-2 and TGF-β1 signalling.
Journal of cellular physiology 2013;228(2):330-40.
2013: Ute Hempel; Peter Dieter; Thomas Hefti; Falko Schlottig
Response of human bone marrow stromal cells, MG-63, and SaOS-2 to titanium-based dental implant surfaces with different topography and surface energy.
Clinical oral implants research 2013;24(2):174-82.
2013: Stefanie Kliemt; Claudia Lange; Stephanie Möller; Wolfgang Otto; Martin von Bergen; Ute Hempel; Vera Hintze; Stefan Kalkhof
Sulfated hyaluronan containing collagen matrices enhance cell-matrix-interaction, endocytosis, and osteogenic differentiation of human mesenchymal stromal cells.
Journal of proteome research 2013;12(1):378-89.
2013: Peter Bernstein; Denis Corbeil; Ute Hempel; Ines Sperling; Stefan Fickert
Progenitor cells from cartilage--no osteoarthritis-grade-specific differences in stem cell marker expression.
Biotechnology progress 2013;29(1):206-12.
2012: Ute Hempel; V Hintze; S Möller; C Noack; Dieter Scharnweber; Matthias Schnabelrauch; Peter Dieter
Sulfated hyaluronan/collagen I matrices enhance the osteogenic differentiation of human mesenchymal stromal cells in vitro even in the absence of dexamethasone.
Acta biomaterialia 2012;8(11):4064-72.
2012: Annette I Garbe; Martin Glösmann; Ute Hempel; Lorenz C Hofbauer; Ricardo Bernhardt; Michael Chopin; Monika Egerbacher; Reinhold G Erben; Anne-Helen Lutter; Stefan Rammelt; Anne Roscher; Christiane Schüler; Rolf Jessberger
Regulation of bone mass and osteoclast function depend on the F-actin modulator SWAP-70.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2012;27(10):2085-96.
2012: C Wolf-Brandstetter; N Theilgaard; S A M Tofail; H-P Wiesmann; S Clyens; A A Gandhi; Ute Hempel; O Korostynska; S Oswald; Dieter Scharnweber
The impact of heat treatment on interactions of contact-poled biphasic calcium phosphates with proteins and cells.
Acta biomaterialia 2012;8(9):3468-77.
2012: Juliane Salbach; Jan-Christoph Simon; Tilman Rachner; Martina Rauner; Ulf Anderegg; Sandra Franz; Ute Hempel; Lorenz C Hofbauer
Regenerative potential of glycosaminoglycans for skin and bone.
Journal of molecular medicine (Berlin, Germany) 2012;90(6):625-35.
2011: Christine Hamann; Ute Hempel; Veit Henkenjohann; Ricardo Bernhardt; Nadja Fratzl-Zelman; Claudia Goettsch; Klaus-Peter Günther; Jan Mettelsiefen; Stefan Rammelt; Martina Rauner; Paul Roschger; Lorenz C Hofbauer
Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function.
American journal of physiology. Endocrinology and metabolism 2011;301(6):E1220-8.
2011: Claudia Goettsch; Ute Hempel; Nicole Pacyna; Martina Rauner; Stefan R Bornstein; Lorenz C Hofbauer
miR-125b regulates calcification of vascular smooth muscle cells.
The American journal of pathology 2011;179(4):1594-600.
2011: C Goettsch; C Hamann; Ute Hempel; Martina Rauner; K Sinningen; S R Bornstein; Lorenz C Hofbauer
Nuclear factor of activated T cells mediates oxidised LDL-induced calcification of vascular smooth muscle cells.
Diabetologia 2011;54(10):2690-701.
2010: Reiner Kunze; Ute Hempel; Peter Dieter
Differential effect of chondroitin-4-sulfate on the immediate and delayed prostaglandin E2 release from osteoblasts.
Prostaglandins & other lipid mediators 2010;92(1-4):8-12.
2010: Ute Hempel; Thomas Hefti; Marie Kalbacova; Cornelia Wolf-Brandstetter; Peter Dieter; Falko Schlottig
Response of osteoblast-like SAOS-2 cells to zirconia ceramics with different surface topographies.
Clinical oral implants research 2010;21(2):174-81.
2010: Reiner Kunze; Manuela Rösler; Stephanie Möller; Matthias Schnabelrauch; Thomas Riemer; Ute Hempel; Peter Dieter
Sulfated hyaluronan derivatives reduce the proliferation rate of primary rat calvarial osteoblasts.
Glycoconjugate journal 2010;27(1):151-8.
2009: A Bernhardt; Anja Lode; C Mietrach; Ute Hempel; Thomas Hanke; Michael Gelinsky
In vitro osteogenic potential of human bone marrow stromal cells cultivated in porous scaffolds from mineralized collagen.
Journal of biomedical materials research. Part A 2009;90(3):852-62.
2009: Susann Helas; Claudia Goettsch; Michael Schoppet; Ute Zeitz; Ute Hempel; Henning Morawietz; Paul J Kostenuik; Reinhold Erben; Lorenz C Hofbauer
Inhibition of receptor activator of NF-kappaB ligand by denosumab attenuates vascular calcium deposition in mice.
The American journal of pathology 2009;175(2):473-8.
2009: Jan Michael; Lena Schönzart; Ina Israel; René Beutner; Dieter Scharnweber; Hartmut Worch; Ute Hempel; Bernd Schwenzer
Oligonucleotide-RGD peptide conjugates for surface modification of titanium implants and improvement of osteoblast adhesion.
Bioconjugate chemistry 2009;20(4):710-8.
2008: Timothy Douglas; Sascha Heinemann; Ute Hempel; Carolin Mietrach; Christiane Knieb; Susanne Bierbaum; Dieter Scharnweber; Hartmut Worch
Characterization of collagen II fibrils containing biglycan and their effect as a coating on osteoblast adhesion and proliferation.
Journal of materials science. Materials in medicine 2008;19(4):1653-60.
2008: Timothy Douglas; Ute Hempel; Carolin Mietrach; Manuela Viola; Davide Vigetti; Sascha Heinemann; Susanne Bierbaum; Dieter Scharnweber; Hartmut Worch
Influence of collagen-fibril-based coatings containing decorin and biglycan on osteoblast behavior.
Journal of biomedical materials research. Part A 2008;84(3):805-16.
2008: Mario Menschikowski; Albert Hagelgans; Ute Hempel; Peter Lattke; Iskander Ismailov; Gabriele Siegert
On interaction of activated protein C with human aortic smooth muscle cells attenuating the secretory group IIA phospholipase A2 expression.
Thrombosis research 2008;122(1):69-76.
2007: Timothy Douglas; Ute Hempel; C Mietrach; Sascha Heinemann; Dieter Scharnweber; Hartmut Worch
Fibrils of different collagen types containing immobilised proteoglycans (PGs) as coatings: characterisation and influence on osteoblast behaviour.
Biomolecular engineering 2007;24(5):455-8.
2007: Bernd Stadlinger; Eckart Pilling; Matthias Huhle; Ronald Mai; Susanne Bierbaum; Ricardo Bernhardt; Dieter Scharnweber; Eberhard Kuhlisch; Ute Hempel; Uwe Eckelt
Influence of extracellular matrix coatings on implant stability and osseointegration: an animal study.
Journal of biomedical materials research. Part B, Applied biomaterials 2007;83(1):222-31.
2007: Marie Kalbacova; Sophie Roessler; Ute Hempel; Roman Tsaryk; Kirsten Peters; Dieter Scharnweber; James C Kirkpatrick; Peter Dieter
The effect of electrochemically simulated titanium cathodic corrosion products on ROS production and metabolic activity of osteoblasts and monocytes/macrophages.
Biomaterials 2007;28(22):3263-72.
2007: Timothy Douglas; Sascha Heinemann; Carolin Mietrach; Ute Hempel; Susanne Bierbaum; Dieter Scharnweber; Hartmut Worch
Interactions of collagen types I and II with chondroitin sulfates A-C and their effect on osteoblast adhesion.
Biomacromolecules 2007;8(4):1085-92.
2007: Roman Tsaryk; Marie Kalbacova; Ute Hempel; Dieter Scharnweber; Ronald E Unger; Peter Dieter; Charles James Kirkpatrick; Kirsten Peters
Response of human endothelial cells to oxidative stress on Ti6Al4V alloy.
Biomaterials 2007;28(5):806-13.
2007: J Michael; René Beutner; Ute Hempel; Dieter Scharnweber; Hartmut Worch; Bernd Schwenzer
Surface modification of titanium-based alloys with bioactive molecules using electrochemically fixed nucleic acids.
Journal of biomedical materials research. Part B, Applied biomaterials 2007;80(1):146-55.
2005: Ihor Zahanich; Eva M Graf; Jürgen F Heubach; Ute Hempel; Sabine Boxberger; Ursula Ravens
Molecular and functional expression of voltage-operated calcium channels during osteogenic differentiation of human mesenchymal stem cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2005;20(9):1637-46.
2005: Mario Menschikowski; Albert Hagelgans; Ben Heyne; Ute Hempel; Volker Neumeister; Peter Goez; Werner Jaross; Gabriele Siegert
Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
Biochimica et biophysica acta 2005;1733(2-3):157-71.
2004: Mario Menschikowski; Albert Hagelgans; Ute Hempel; Gabriele Siegert
Glycogen synthase kinase-3beta negatively regulates group IIA phospholipase A2 expression in human aortic smooth muscle and HepG2 hepatoma cells.
FEBS letters 2004;577(1-2):81-6.
2004: Ute Hempel; Antje Reinstorf; Maja Poppe; U Fischer; Michael Gelinsky; Wolfgang Pompe; Klaus-Wolfgang Wenzel
Proliferation and differentiation of osteoblasts on Biocement D modified with collagen type I and citric acid.
Journal of biomedical materials research. Part B, Applied biomaterials 2004;71(1):130-43.
2004: Falk Fichtner; Roland Koslowski; Antje Augstein; Ute Hempel; Cora Röhlecke; Michael Kasper
Bleomycin induces IL-8 and ICAM-1 expression in microvascular pulmonary endothelial cells.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2004;55(6):497-503.
2004: Antje Reinstorf; M Ruhnow; Michael Gelinsky; Wolfgang Pompe; Ute Hempel; Klaus-Wolfgang Wenzel; P Simon
Phosphoserine--a convenient compound for modification of calcium phosphate bone cement collagen composites.
Journal of materials science. Materials in medicine 2004;15(4):451-5.
2003: Susanne Bierbaum; Ute Hempel; Ulrike Geissler; Thomas Hanke; Dieter Scharnweber; Klaus-Wolfgang Wenzel; Hartmut Worch
Modification of Ti6AL4V surfaces using collagen I, III, and fibronectin. II. Influence on osteoblast responses.
Journal of biomedical materials research. Part A 2003;67(2):431-8.
2003: Susanne Bierbaum; René Beutner; Thomas Hanke; Dieter Scharnweber; Ute Hempel; Hartmut Worch
Modification of Ti6Al4V surfaces using collagen I, III, and fibronectin. I. Biochemical and morphological characteristics of the adsorbed matrix.
Journal of biomedical materials research. Part A 2003;67(2):421-30.
2003: U Fischer; Ute Hempel; D Becker; Susanne Bierbaum; Dieter Scharnweber; Hartmut Worch; Klaus-Wolfgang Wenzel
Transforming growth factor beta1 immobilized adsorptively on Ti6Al4V and collagen type I coated Ti6Al4V maintains its biological activity.
Biomaterials 2003;24(15):2631-41.
2002: Wolfgang Schwab; Ulrich Friess; Ute Hempel; Eva Schulze; Zenji Makita; Michael Kasper; Hans-Georg Simank
Immunohistochemical demonstration of -(carboxymethyl)lysine protein adducts in normal and osteoarthritic cartilage.
Histochemistry and cell biology 2002;117(6):541-6.
2002: D Becker; Ulrike Geissler; Ute Hempel; Susanne Bierbaum; Dieter Scharnweber; Hartmut Worch; Klaus-Wolfgang Wenzel
Proliferation and differentiation of rat calvarial osteoblasts on type I collagen-coated titanium alloy.
Journal of biomedical materials research 2002;59(3):516-27.
2000: Ulrike Geissler; Ute Hempel; C Wolf; Dieter Scharnweber; Hartmut Worch; Klaus-Wolfgang Wenzel
Collagen type I-coating of Ti6Al4V promotes adhesion of osteoblasts.
Journal of biomedical materials research 2000;51(4):752-60.
1999: Wolfgang Schwab; Ferruccio Galbiati; Daniela Volonte; Ute Hempel; Klaus-Wolfgang Wenzel; Richard H W Funk; M P Lisanti; Michael Kasper
Characterisation of caveolins from cartilage: expression of caveolin-1, -2 and -3 in chondrocytes and in alginate cell culture of the rat tibia.
Histochemistry and cell biology 1999;112(1):41-9.
1999: Wolfgang Schwab; Ute Hempel; Richard H W Funk; Michael Kasper
Ultrastructural identification of caveolae and immunocytochemical as well as biochemical detection of caveolin in chondrocytes.
The Histochemical journal 1999;31(5):315-20.
1999: Peter Dieter; Ute Hempel; Sabine Kamionka; Angelika Kolada; B Malessa; E Fitzke; T A Tran-Thi
Prostaglandin E2 affects differently the release of inflammatory mediators from resident macrophages by LPS and muramyl tripeptides.
Mediators of inflammation 1999;8(6):295-303.
1999: Peter Dieter; Ute Hempel; B Malessa; E Fitzke; T A Tran-Thi; J MacLouf; C Créminon; Y Kanaoka; Y Urade
Lipopolysaccharide- and liposome-encapsulated MTP-PE-induced formation of eicosanoids, nitric oxide and tumor necrosis factor-alpha in macrophages.
Advances in experimental medicine and biology 1999;469():443-8.
1998: A Axmann; D Seidel; T Reimann; Ute Hempel; Klaus-Wolfgang Wenzel
Transforming growth factor-beta1-induced activation of the Raf-MEK-MAPK signaling pathway in rat lung fibroblasts via a PKC-dependent mechanism.
Biochemical and biophysical research communications 1998;249(2):456-60.
1998: Michael Kasper; T Reimann; Ute Hempel; Klaus-Wolfgang Wenzel; A Bierhaus; D Schuh; V Dimmer; Gunter Haroske; M Müller
Loss of caveolin expression in type I pneumocytes as an indicator of subcellular alterations during lung fibrogenesis.
Histochemistry and cell biology 1998;109(1):41-8.
1997: T Reimann; Ute Hempel; S Krautwald; A Axmann; Renate J Scheibe; D Seidel; Klaus-Wolfgang Wenzel
Transforming growth factor-beta1 induces activation of Ras, Raf-1, MEK and MAPK in rat hepatic stellate cells.
FEBS letters 1997;403(1):57-60.
1995: Mario Menschikowski; Ute Hempel; G Dinnebier; Peter Lattke; Klaus-Wolfgang Wenzel; Werner Jaross
Changes in epitope exposition of apolipoprotein A-I on the surface of high density lipoproteins after phospholipase A2 treatment.
Atherosclerosis 1995;117(2):159-67.