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William Hennah

Research Profile

Chemicals & Drugs

Genes & Molecular Sequences

Disorders

Physiology

Geographic Areas

Finland

Concepts & Ideas

Anatomy

Chromosomes, Human, Pair 1

Co-author Network

Publications

TOP 3
Verian Bader; Nicholas J Bradshaw; Jesper Ekelund; Stefano Ferrea; William Hennah; Uwe Henning; Maria Hipolito; Koko Ishizuka; Marjo-Riitta Järvelin; S Rutger Leliveld; Chi-Ying Lin; Christian Luckhaus; Evaristus Nwulia; Ingrid Prikulis; Narayan Rai; Adriana Ramos; Jesús R Requena; Isaac Rosa; Akira Sawa; Liisa Tomppo; Svenja V Trossbach; Juha Veijola; Ángel García; Carsten Korth
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Liisa Tomppo; Juha Veijola; Jesper Ekelund; Marjo-Riitta Järvelin; Dirk Lichtermann; William Hennah
DISC1 conditioned GWAS for psychosis proneness in a large Finnish birth cohort.
Goultchira Chakirova; Heather C Whalley; Pippa A Thomson; William Hennah; T William J Moorhead; Killian A Welch; Stephen Giles; Jeremy Hall; Eve C Johnstone; Stephen M Lawrie; David J Porteous; Verity J Brown; Andrew M McIntosh
The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia.

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All Publications

2012: Verian Bader; Nicholas J Bradshaw; Jesper Ekelund; Stefano Ferrea; William Hennah; Uwe Henning; Maria Hipolito; Koko Ishizuka; Marjo-Riitta Järvelin; S Rutger Leliveld; Chi-Ying Lin; Christian Luckhaus; Evaristus Nwulia; Ingrid Prikulis; Narayan Rai; Adriana Ramos; Jesús R Requena; Isaac Rosa; Akira Sawa; Liisa Tomppo; Svenja V Trossbach; Juha Veijola; Ángel García; Carsten Korth
Proteomic, genomic and translational approaches identify CRMP1 for a role in schizophrenia and its underlying traits.
Human molecular genetics 2012;21(20):4406-18.
2012: Liisa Tomppo; Juha Veijola; Jesper Ekelund; Marjo-Riitta Järvelin; Dirk Lichtermann; William Hennah
DISC1 conditioned GWAS for psychosis proneness in a large Finnish birth cohort.
PloS one 2012;7(2):e30643.
2011: Goultchira Chakirova; Heather C Whalley; Pippa A Thomson; William Hennah; T William J Moorhead; Killian A Welch; Stephen Giles; Jeremy Hall; Eve C Johnstone; Stephen M Lawrie; David J Porteous; Verity J Brown; Andrew M McIntosh
The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia.
Psychiatry research 2011;192(1):20-8.
2010: Sarah E Harris; William Hennah; Pippa A Thomson; M Luciano; John M Starr; David J Porteous; Ian J Deary
Variation in DISC1 is associated with anxiety, depression and emotional stability in elderly women.
Molecular psychiatry 2010;15(3):232-4.
2009: Jaana Wessman; Tiina Paunio; Annamari Tuulio-Henriksson; M Koivisto; Timo Partonen; Jaana Suvisaari; Joni A Turunen; Juho Wedenoja; William Hennah; Olli P H Pietiläinen; Jouko Lönnqvist; Heikki Mannila; Leena Peltonen
Mixture model clustering of phenotype features reveals evidence for association of DTNBP1 to a specific subtype of schizophrenia.
Biological psychiatry 2009;66(11):990-6.
2009: William Hennah; P Thomson; A McQuillin; N Bass; A Loukola; A Anjorin; D H R Blackwood; D Curtis; Ian J Deary; Sarah E Harris; E T Isometsä; J Lawrence; J Lönnqvist; Walter Muir; A Palotie; Timo Partonen; T Paunio; E Pylkkö; M Robinson; P Soronen; K Suominen; J Suvisaari; S Thirumalai; D St Clair; H Gurling; L Peltonen; David J Porteous
DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.
Molecular psychiatry 2009;14(9):865-73.
2009: Olli P H Pietiläinen; Tiina Paunio; Anu Loukola; Annamari Tuulio-Henriksson; Tuula Kieseppä; Paul Thompson; Arthur W Toga; Theo G M van Erp; Karri Silventoinen; Pia Soronen; William Hennah; Joni A Turunen; Juho Wedenoja; Outi M Palo; Kaisa Silander; Jouko Lönnqvist; Jaakko Kaprio; Tyrone D Cannon; Leena Peltonen
Association of AKT1 with verbal learning, verbal memory, and regional cortical gray matter density in twins.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(5):683-92.
2009: Liisa Tomppo; William Hennah; Päivi Lahermo; Anu Loukola; Annamari Tuulio-Henriksson; Jaana Suvisaari; Timo Partonen; Jesper Ekelund; Jouko Lönnqvist; Leena Peltonen
Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.
Biological psychiatry 2009;65(12):1055-62.
2009: Liisa Tomppo; William Hennah; Jouko Miettunen; Marjo-Riitta Järvelin; Juha Veijola; Samuli Ripatti; Päivi Lahermo; Dirk Lichtermann; Leena Peltonen; Jesper Ekelund
Association of variants in DISC1 with psychosis-related traits in a large population cohort.
Archives of general psychiatry 2009;66(2):134-41.
2009: William Hennah; David Porteous
The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.
PloS one 2009;4(3):e4906.
2008: Pia Soronen; Kaisa Silander; Mervi Antila; Outi M Palo; Annamari Tuulio-Henriksson; Tuula Kieseppä; Pekka Ellonen; Juho Wedenoja; Joni A Turunen; Olli P H Pietiläinen; William Hennah; Jouko Lönnqvist; Leena Peltonen; Timo Partonen; Tiina Paunio
Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample.
Biological psychiatry 2008;64(5):438-42.
2008: H Kilpinen; Tero Ylisaukko-Oja; William Hennah; Outi M Palo; Teppo Varilo; Raija Vanhala; Taina Nieminen-von Wendt; Lennart von Wendt; Tiina Paunio; Leena Peltonen
Association of DISC1 with autism and Asperger syndrome.
Molecular psychiatry 2008;13(2):187-96.
2007: Weidong Li; Yu Zhou; J David Jentsch; Robert A M Brown; Xiaoli Tian; Dan Ehninger; William Hennah; Leena Peltonen; Jouko Lönnqvist; Matti O Huttunen; Jaakko Kaprio; Joshua T Trachtenberg; Alcino J Silva; Tyrone D Cannon
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):18280-5.
2007: Outi M Palo; Mervi Antila; Kaisa Silander; William Hennah; Helena Kilpinen; Pia Soronen; Annamari Tuulio-Henriksson; Tuula Kieseppä; Timo Partonen; Jouko Lönnqvist; Leena Peltonen; Tiina Paunio
Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.
Human molecular genetics 2007;16(20):2517-28.
2007: Joni A Turunen; Juho O Peltonen; Olli P H Pietiläinen; William Hennah; Anu Loukola; Tiina Paunio; Kaisa Silander; Jesper Ekelund; Teppo Varilo; Timo Partonen; Jouko Lönnqvist; Leena Peltonen
The role of DTNBP1, NRG1, and AKT1 in the genetics of schizophrenia in Finland.
Schizophrenia research 2007;91(1-3):27-36.
2007: William Hennah; Liisa Tomppo; Tero Hiekkalinna; Outi M Palo; Helena Kilpinen; Jesper Ekelund; Annamari Tuulio-Henriksson; Kaisa Silander; Timo Partonen; Tiina Paunio; Joseph D Terwilliger; Jouko Lönnqvist; Leena Peltonen
Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.
Human molecular genetics 2007;16(5):453-62.
2006: William Hennah; Pippa Thomson; Leena Peltonen; David Porteous
Genes and schizophrenia: beyond schizophrenia: the role of DISC1 in major mental illness.
Schizophrenia bulletin 2006;32(3):409-16.
2005: William Hennah; Annamari Tuulio-Henriksson; Tiina Paunio; Jesper Ekelund; Teppo Varilo; Timo Partonen; Tyrone D Cannon; Jouko Lönnqvist; Leena Peltonen
A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.
Molecular psychiatry 2005;10(12):1097-103.
2005: Tyrone D Cannon; William Hennah; Theo G M van Erp; Paul M Thompson; Jouko Lonnqvist; Matti O Huttunen; Timothy L Gasperoni; Annamari Tuulio-Henriksson; Tiia Pirkola; Arthur W Toga; Jaakko Kaprio; John C Mazziotta; Leena Peltonen
Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory.
Archives of general psychiatry 2005;62(11):1205-13.
2004: Jesper Ekelund; William Hennah; Tero Hiekkalinna; A Parker; J Meyer; Jouko Lönnqvist; Leena Peltonen
Replication of 1q42 linkage in Finnish schizophrenia pedigrees.
Molecular psychiatry 2004;9(11):1037-41.
2004: William Hennah; Teppo Varilo; Tiina Paunio; Leena Peltonen
Haplotype analysis and identification of genes for a complex trait: examples from schizophrenia.
Annals of medicine 2004;36(5):322-31.
2003: William Hennah; Teppo Varilo; Marjo Kestilä; Tiina Paunio; Ritva Arajärvi; Jari Haukka; Alex Parker; Rory Martin; Steve Levitzky; Timo Partonen; Joanne Meyer; Jouko Lönnqvist; Leena Peltonen; Jesper Ekelund
Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects.
Human molecular genetics 2003;12(23):3151-9.
2003: Heikki Mannila; M Koivisto; Markus Perola; Teppo Varilo; William Hennah; Jesper Ekelund; M Lukk; Leena Peltonen; Esko Ukkonen
Minimum description length block finder, a method to identify haplotype blocks and to compare the strength of block boundaries.
American journal of human genetics 2003;73(1):86-94.
2003: M Koivisto; Markus Perola; Teppo Varilo; William Hennah; Jesper Ekelund; M Lukk; Leena Peltonen; Esko Ukkonen; Heikki Mannila
An MDL method for finding haplotype blocks and for estimating the strength of haplotype block boundaries.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 2003;():502-13.