FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Lothar Hennighausen

Research Profile

Living Beings

Anatomy

Chemicals & Drugs

Concepts & Ideas

Lactation

Physiology

Co-author Network

Publications

TOP 3
Daisuke Yamaji; Keunsoo Kang; Gertraud W Robinson; Lothar Hennighausen
Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.
Keunsoo Kang; Gertraud W Robinson; Lothar Hennighausen
Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules.
Atsushi Hosui; Tatsuya Kanto; Peter Klover; Masaki Mori; Hiroaki Nagano; Yuichiro Doki; Norio Hayashi; Lothar Hennighausen; Naoki Hiramatsu; Tomohide Tatsumi; Akio Uemura; Tetsuo Takehara
Suppression of signal transducers and activators of transcription 1 in hepatocellular carcinoma is associated with tumor progression.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Lothar Hennighausen (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Daisuke Yamaji; Keunsoo Kang; Gertraud W Robinson; Lothar Hennighausen
Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.
Nucleic acids research 2013;41(3):1622-36.
2013: Keunsoo Kang; Gertraud W Robinson; Lothar Hennighausen
Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules.
BMC genomics 2013;14():4.
2012: Atsushi Hosui; Tatsuya Kanto; Peter Klover; Masaki Mori; Hiroaki Nagano; Yuichiro Doki; Norio Hayashi; Lothar Hennighausen; Naoki Hiramatsu; Tomohide Tatsumi; Akio Uemura; Tetsuo Takehara
Suppression of signal transducers and activators of transcription 1 in hepatocellular carcinoma is associated with tumor progression.
International journal of cancer. Journal international du cancer 2012;131(12):2774-84.
2012: Carly Page; Yong Zhang; Lindsay Goicochea; Lothar Hennighausen; Michael J Holtzman; Peter Klover; Krystal Matthews; Matthew Frieman
Induction of alternatively activated macrophages enhances pathogenesis during severe acute respiratory syndrome coronavirus infection.
Journal of virology 2012;86(24):13334-49.
2012: Ji Hoon Yu; Bing-Mei Zhu; Keunsoo Kang; Gregory Riedlinger; Lothar Hennighausen
The liver-specific tumor suppressor STAT5 controls expression of the reactive oxygen species-generating enzyme NOX4 and the proapoptotic proteins PUMA and BIM in mice.
Hepatology (Baltimore, Md.) 2012;56(6):2375-86.
2012: Yonatan Feuermann; Keunsoo Kang; Noa Raviv; Gertraud W Robinson; Daisuke Yamaji; Bing-Mei Zhu; Lothar Hennighausen
The miR-17/92 cluster is targeted by STAT5 but dispensable for mammary development.
Genesis (New York, N.Y. : 2000) 2012;50(9):665-71.
2012: Bing-Mei Zhu; Weiping Chen; Keunsoo Kang; Daeyoup Lee; Harold E Smith; Hong-Wei Sun; Lai Wei; Ji Hoon Yu; Lothar Hennighausen
Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes.
Nucleic acids research 2012;40(10):4461-72.
2011: Myunggi Baik; Ji Hoon Yu; Lothar Hennighausen
Growth hormone-STAT5 regulation of growth, hepatocellular carcinoma, and liver metabolism.
Annals of the New York Academy of Sciences 2011;1229():29-37.
2011: Gertraud W Robinson; Lothar Hennighausen
MMTV-Cre transgenes can adversely affect lactation: considerations for conditional gene deletion in mammary tissue.
Analytical biochemistry 2011;412(1):92-5.
2011: Kyung Hyun Yoo; Myunggi Baik; Lothar Hennighausen
Context-Specific Growth Hormone Signaling through the Transcription Factor STAT5: Implications for the Etiology of Hepatosteatosis and Hepatocellular Carcinoma.
Genes & cancer 2011;2(1):3-9.
2010: Peter J Klover; William J Muller; Gertraud W Robinson; Ruth M Pfeiffer; Daisuke Yamaji; Lothar Hennighausen
Loss of STAT1 from mouse mammary epithelium results in an increased Neu-induced tumor burden.
Neoplasia (New York, N.Y.) 2010;12(11):899-905.
2010: Ji Hoon Yu; Bing-Mei Zhu; Mark Wickre; Gregory Riedlinger; Weiping Chen; Atsushi Hosui; Gertraud W Robinson; Lothar Hennighausen
The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B negatively regulate cell proliferation through the activation of cyclin-dependent kinase inhibitor 2b (Cdkn2b) and Cdkn1a expression.
Hepatology (Baltimore, Md.) 2010;52(5):1808-18.
2010: Akiko Kimura; Cyril Martin; Gertraud W Robinson; James M Simone; Weiping Chen; Mark C Wickre; John J O'Shea; Lothar Hennighausen
The gene encoding the hematopoietic stem cell regulator CCN3/NOV is under direct cytokine control through the transcription factors STAT5A/B.
The Journal of biological chemistry 2010;285(43):32704-9.
2010: Andrea Hoelbl; Christian Schuster; Boris Kovacic; Bingmei Zhu; Mark Wickre; Maria A Hoelzl; Sabine Fajmann; Florian Grebien; Wolfgang Warsch; Gabriele Stengl; Lothar Hennighausen; Valeria Poli; Hartmut Beug; Richard Moriggl; Veronika Sexl
Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.
EMBO molecular medicine 2010;2(3):98-110.
2010: Jung-Hyun Park; Stanley Adoro; Terry Guinter; Batu Erman; Amala S Alag; Marta Catalfamo; Motoko Y Kimura; Yongzhi Cui; Philip J Lucas; Ronald E Gress; Masato Kubo; Lothar Hennighausen; Lionel Feigenbaum; Alfred Singer
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.
Nature immunology 2010;11(3):257-64.
2009: Hayato Hikita; Tetsuo Takehara; Takahiro Kodama; S Shimizu; Atsushi Hosui; Takuya Miyagi; Tomohide Tatsumi; Hisashi Ishida; Kazuyoshi Ohkawa; Wei Li; Tatsuya Kanto; Naoki Hiramatsu; Lothar Hennighausen; Xiao-Ming Yin; Norio Hayashi
BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
Hepatology (Baltimore, Md.) 2009;50(6):1972-80.
2009: Akiko Kimura; Michael A Rieger; James M Simone; Weiping Chen; Mark C Wickre; Bing-Mei Zhu; Philipp S Hoppe; John O'Shea; Timm Schroeder; Lothar Hennighausen
The transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesis.
Blood 2009;114(21):4721-8.
2009: Daisuke Yamaji; Risu Na; Yonatan Feuermann; Susanne Pechhold; Weiping Chen; Gertraud W Robinson; Lothar Hennighausen
Development of mammary luminal progenitor cells is controlled by the transcription factor STAT5A.
Genes & development 2009;23(20):2382-7.
2009: Hayato Hikita; Tetsuo Takehara; Satoshi Shimizu; Takahiro Kodama; Wei Li; Takuya Miyagi; Atsushi Hosui; Hisashi Ishida; Kazuyoshi Ohkawa; Tatsuya Kanto; Naoki Hiramatsu; Xiao-Ming Yin; Lothar Hennighausen; Tomohide Tatsumi; Norio Hayashi
Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver.
Hepatology (Baltimore, Md.) 2009;50(4):1217-26.
2009: Peter Klover; Weiping Chen; Bing-Mei Zhu; Lothar Hennighausen
Skeletal muscle growth and fiber composition in mice are regulated through the transcription factors STAT5a/b: linking growth hormone to the androgen receptor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(9):3140-8.
2009: Atsushi Hosui; Akiko Kimura; Daisuke Yamaji; Bing-Mei Zhu; Risu Na; Lothar Hennighausen
Loss of STAT5 causes liver fibrosis and cancer development through increased TGF-{beta} and STAT3 activation.
The Journal of experimental medicine 2009;206(4):819-31.
2008: Yasushi Oshima; Toru Akiyama; Atsuhiko Hikita; Mitsuyasu Iwasawa; Yuichi Nagase; Masaki Nakamura; Hidetoshi Wakeyama; Naohiro Kawamura; Toshiyuki Ikeda; Ung-il Chung; Lothar Hennighausen; Hiroshi Kawaguchi; Kozo Nakamura; Sakae Tanaka
Pivotal role of Bcl-2 family proteins in the regulation of chondrocyte apoptosis.
The Journal of biological chemistry 2008;283(39):26499-508.
2008: Bing-Mei Zhu; Sara K McLaughlin; Risu Na; Jie Liu; Yongzhi Cui; Cyril Martin; Akiko Kimura; Gertraud W Robinson; Nancy C Andrews; Lothar Hennighausen
Hematopoietic-specific Stat5-null mice display microcytic hypochromic anemia associated with reduced transferrin receptor gene expression.
Blood 2008;112(5):2071-80.
2008: Atsushi Hosui; Lothar Hennighausen
Genomic dissection of the cytokine-controlled STAT5 signaling network in liver.
Physiological genomics 2008;34(2):135-43.
2008: Bing-Mei Zhu; Yuko Ishida; Gertraud W Robinson; Margit Pacher-Zavisin; Akihiko Yoshimura; Philip M Murphy; Lothar Hennighausen
SOCS3 negatively regulates the gp130-STAT3 pathway in mouse skin wound healing.
The Journal of investigative dermatology 2008;128(7):1821-9.
2008: Lothar Hennighausen; Gertraud W Robinson
Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B.
Genes & development 2008;22(6):711-21.
2008: Fulu Liu; Ghada Kunter; Maxwell M Krem; William C Eades; Jennifer A Cain; Michael H Tomasson; Lothar Hennighausen; Daniel C Link
Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5.
The Journal of clinical investigation 2008;118(3):946-55.
2008: Ji-Yeon Lee; Heike Muenzberg; Oksana Gavrilova; Jacquelyn A Reed; Darlene Berryman; Eneida C Villanueva; Gwendolyn W Louis; Gina M Leinninger; Stefano Bertuzzi; Randy J Seeley; Gertraud W Robinson; Martin G Myers Jr; Lothar Hennighausen
Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.
PloS one 2008;3(2):e1639.
2007: Yi Le; Bing-Mei Zhu; Brendan Harley; Shin-Young Park; Takashi Kobayashi; John P Manis; Hongbo R Luo; Akihiko Yoshimura; Lothar Hennighausen; Leslie E Silberstein
SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis.
Immunity 2007;27(5):811-23.
2007: Ji-Yeon Lee; Oksana Gavrilova; Behrous Davani; Risu Na; Gertraud W Robinson; Lothar Hennighausen
The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.
Biochimica et biophysica acta 2007;1773(9):1455-61.
2007: Yongzhi Cui; Atsushi Hosui; Rui Sun; Kezhen Shen; Oksana Gavrilova; Weiping Chen; Margaret C Cam; Bin Gao; Gertraud W Robinson; Lothar Hennighausen
Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration.
Hepatology (Baltimore, Md.) 2007;46(2):504-13.
2007: Zhengju Yao; Yuka Kanno; Marc Kerenyi; Geoffrey Stephens; Lydia Durant; Wendy T Watford; Arian Dominic John laurence; Gertraud W Robinson; Ethan M Shevach; Richard Moriggl; Lothar Hennighausen; Changyou Wu; John O'Shea
Nonredundant roles for Stat5a/b in directly regulating Foxp3.
Blood 2007;109(10):4368-75.
2007: Minita G Holloway; Yongzhi Cui; Ekaterina V Laz; Atsushi Hosui; Lothar Hennighausen; David J Waxman
Loss of sexually dimorphic liver gene expression upon hepatocyte-specific deletion of Stat5a-Stat5b locus.
Endocrinology 2007;148(5):1977-86.
2007: Peter Klover; Lothar Hennighausen
Postnatal body growth is dependent on the transcription factors signal transducers and activators of transcription 5a/b in muscle: a role for autocrine/paracrine insulin-like growth factor I.
Endocrinology 2007;148(4):1489-97.
2007: Arian Dominic John laurence; Cristina M Tato; Todd S Davidson; Yuka Kanno; Zhi Chen; Zhengju Yao; Rebecca B Blank; Françoise Meylan; Richard Siegel; Lothar Hennighausen; Ethan M Shevach; John O'Shea
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation.
Immunity 2007;26(3):371-81.
2007: Gertraud W Robinson; Margit Pacher-Zavisin; Bing-Mei Zhu; Akihiko Yoshimura; Lothar Hennighausen
Socs 3 modulates the activity of the transcription factor Stat3 in mammary tissue and controls alveolar homeostasis.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(3):654-61.
2007: Alejandro V Villarino; Cristina M Tato; Jason S Stumhofer; Zhengju Yao; Yongzhi K Cui; Lothar Hennighausen; John O'Shea; Christopher A Hunter
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals.
The Journal of experimental medicine 2007;204(1):65-71.
2006: Jason S Stumhofer; Arian Dominic John laurence; Emma H Wilson; Elaine Huang; Cristina M Tato; Leanne M Johnson; Alejandro V Villarino; Qiulong Huang; Akihiko Yoshimura; David Sehy; Christiaan J M Saris; John O'Shea; Lothar Hennighausen; Matthias Ernst; Christopher A Hunter
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system.
Nature immunology 2006;7(9):937-45.
2006: Yi Sun; Kelli Boyd; Wu Xu; Jing Ma; Carl W Jackson; Amina Fu; Jonathan Shillingford; Gertraud W Robinson; Lothar Hennighausen; Johann K Hitzler; Zhigui Ma; Stephan W Morris
Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function.
Molecular and cellular biology 2006;26(15):5809-26.
2006: Andrea Hoelbl; Boris Kovacic; Marc Kerenyi; Olivia Simma; Wolfgang Warsch; Yongzhi Cui; Hartmut Beug; Lothar Hennighausen; Richard Moriggl; Veronika Sexl
Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.
Blood 2006;107(12):4898-906.
2006: Zhi Chen; Arian Dominic John laurence; Yuka Kanno; Margit Pacher-Zavisin; Bing-Mei Zhu; Cristina M Tato; Akihiko Yoshimura; Lothar Hennighausen; John O'Shea
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(21):8137-42.
2006: Krista D Buono; Gertraud W Robinson; Cyril Martin; Shaolin Shi; Pamela Stanley; Kenji Tanigaki; Tasuku Honjo; Lothar Hennighausen
The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy.
Developmental biology 2006;293(2):565-80.
2006: Ji-Yeon Lee; Michael Ristow; Xueying Lin; Morris F White; Mark Magnuson; Lothar Hennighausen
RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function.
The Journal of biological chemistry 2006;281(5):2649-53.
2006: Zhengju Yao; Yongzhi Cui; Wendy T Watford; Jay H Bream; Kunihiro Yamaoka; Bruce D Hissong; Denise Li; Scott K Durum; Qiong Jiang; Avinash Bhandoola; Lothar Hennighausen; John O'Shea
Stat5a/b are essential for normal lymphoid development and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):1000-5.
2005: Fabienne Le Provost; Keiko Miyoshi; Jean-Luc Vilotte; Brian Bierie; Gertraud W Robinson; Lothar Hennighausen
SOCS3 promotes apoptosis of mammary differentiated cells.
Biochemical and biophysical research communications 2005;338(4):1696-701.
2005: Muthusamy Thangaraju; Martina Rudelius; Brian Bierie; Mark Raffeld; Shyam K Sharan; Lothar Hennighausen; A-Mei Huang; Esta Sterneck
C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution.
Development (Cambridge, England) 2005;132(21):4675-85.
2005: Ji-Yeon Lee; Lothar Hennighausen
The transcription factor Stat3 is dispensable for pancreatic beta-cell development and function.
Biochemical and biophysical research communications 2005;334(3):764-8.
2005: Lothar Hennighausen; Gertraud W Robinson
Information networks in the mammary gland.
Nature reviews. Molecular cell biology 2005;6(9):715-25.
2005: Marko Pesu; John O'Shea; Lothar Hennighausen; Olli Silvennoinen
Identification of an acquired mutation in Jak2 provides molecular insights into the pathogenesis of myeloproliferative disorders.
Molecular interventions 2005;5(4):211-5.
2005: Hong Zhao; Yongzhi Cui; Joëlle Dupont; Hui Sun; Lothar Hennighausen; Shoshana Yakar
Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.
Cancer research 2005;65(15):6864-73.
2004: Ling Zhao; Stefan Hart; JrGang Cheng; J Joseph Melenhorst; Brian Bierie; Matthias Ernst; Colin Stewart; Fred Schaper; Peter C Heinrich; Axel Ullrich; Gertraud W Robinson; Lothar Hennighausen
Mammary gland remodeling depends on gp130 signaling through Stat3 and MAPK.
The Journal of biological chemistry 2004;279(42):44093-100.
2004: Tetsuo Takehara; Tomohide Tatsumi; Takahiro Suzuki; Edmund B Rucker; Lothar Hennighausen; Masahisa Jinushi; Takuya Miyagi; Yoshiyuki Kanazawa; Norio Hayashi
Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.
Gastroenterology 2004;127(4):1189-97.
2004: Huiming Hon; Edmund B Rucker; Lothar Hennighausen; Joshy Jacob
bcl-xL is critical for dendritic cell survival in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4425-32.
2004: Yongzhi Cui; Gregory Riedlinger; Keiko Miyoshi; Wei Tang; Cuiling Li; Chu-Xia Deng; Gertraud W Robinson; Lothar Hennighausen
Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.
Molecular and cellular biology 2004;24(18):8037-47.
2004: Brian Bierie; Micah Edwin; J Joseph Melenhorst; Lothar Hennighausen
The proliferation associated nuclear element (PANE1) is conserved between mammals and fish and preferentially expressed in activated lymphoid cells.
Gene expression patterns : GEP 2004;4(4):389-95.
2004: Sylvaine Cases; Ping Zhou; Jonathan Shillingford; Bryony S Wiseman; Jo Dee Fish; Christina S Angle; Lothar Hennighausen; Zena Werb; Robert V Farese
Development of the mammary gland requires DGAT1 expression in stromal and epithelial tissues.
Development (Cambridge, England) 2004;131(13):3047-55.
2004: Jennifer L Evarts; John J Rasweiler; Richard R Behringer; Lothar Hennighausen; Gertraud W Robinson
A morphological and immunohistochemical comparison of mammary tissues from the short-tailed fruit bat (Carollia perspicillata) and the mouse.
Biology of reproduction 2004;70(6):1573-9.
2004: Céline Bry; Karen Maass; Keiko Miyoshi; Klaus Willecke; Thomas Ott; Gertraud W Robinson; Lothar Hennighausen
Loss of connexin 26 in mammary epithelium during early but not during late pregnancy results in unscheduled apoptosis and impaired development.
Developmental biology 2004;267(2):418-29.
2004: Rashmi V Nemade; Brian Bierie; Masahiro Nozawa; Celine Bry; Gilbert H Smith; Valera Vasioukhin; Elaine Fuchs; Lothar Hennighausen
Biogenesis and function of mouse mammary epithelium depends on the presence of functional alpha-catenin.
Mechanisms of development 2004;121(1):91-9.
2003: Wenmei Li; Wenhui Qiao; Lin Chen; Xiaoling Xu; Xiao Yang; Dan Li; Cuiling Li; Steven G Brodie; Michael M Meguid; Lothar Hennighausen; Chu-Xia Deng
Squamous cell carcinoma and mammary abscess formation through squamous metaplasia in Smad4/Dpc4 conditional knockout mice.
Development (Cambridge, England) 2003;130(24):6143-53.
2003: Marta I Gallego; Brian Bierie; Lothar Hennighausen
Targeted expression of HGF/SF in mouse mammary epithelium leads to metastatic adenosquamous carcinomas through the activation of multiple signal transduction pathways.
Oncogene 2003;22(52):8498-508.
2003: Weiwen Long; Kay-Uwe Wagner; K C Kent Lloyd; Nadine Binart; Jonathan Shillingford; Lothar Hennighausen; Frank E Jones
Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.
Development (Cambridge, England) 2003;130(21):5257-68.
2003: Yiping Wu; Karen Cui; Keiko Miyoshi; Lothar Hennighausen; Jeffrey E Green; Jennifer Setser; Derek LeRoith; Shoshana Yakar
Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
Cancer research 2003;63(15):4384-8.
2003: Jean-Pierre Renou; Brian Bierie; Keiko Miyoshi; Yongzhi Cui; Jean Djiane; Moshe Reichenstein; Moshe Shani; Lothar Hennighausen
Identification of genes differentially expressed in mouse mammary epithelium transformed by an activated beta-catenin.
Oncogene 2003;22(29):4594-610.
2003: Brian Bierie; Masahiro Nozawa; Jean-Pierre Renou; Jonathan Shillingford; Fanta Morgan; Takami Oka; Makoto M Taketo; Robert Cardiff; Keiko Miyoshi; Kay-Uwe Wagner; Gertraud W Robinson; Lothar Hennighausen
Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation.
Oncogene 2003;22(25):3875-87.
2003: Jonathan Shillingford; Keiko Miyoshi; Gertraud W Robinson; Brian Bierie; Yixue Cao; Michael Karin; Lothar Hennighausen
Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2003;51(5):555-65.
2003: Easwari Kumaraswamy; Bradley A Carlson; Fanta Morgan; Keiko Miyoshi; Gertraud W Robinson; Dan Su; Shulin Wang; Eileen Southon; Lino Tessarollo; Byeong Jae Lee; Vadim N Gladyshev; Lothar Hennighausen; Dolph L Hatfield
Selective removal of the selenocysteine tRNA [Ser]Sec gene (Trsp) in mouse mammary epithelium.
Molecular and cellular biology 2003;23(5):1477-88.
2003: Kay-Uwe Wagner; Andrea Krempler; Yongyue Qi; KyungRan Park; MaLinda D Henry; Aleata A Triplett; Gregory Riedlinger; Edmund B Rucker III; Lothar Hennighausen
Tsg101 is essential for cell growth, proliferation, and cell survival of embryonic and adult tissues.
Molecular and cellular biology 2003;23(1):150-62.
2002: Jeffrey E Green; Robert Cardiff; Lothar Hennighausen; Lalage M Wakefield; Ulrike Wagner; Eva Lee; Jeffrey Rosen; Daniel Medina; Alexander Nitkin; Edison Liu
Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM.
Transgenic research 2002;11(6):635-6.
2002: Ling Zhao; J Joseph Melenhorst; Lothar Hennighausen
Loss of interleukin 6 results in delayed mammary gland involution: a possible role for mitogen-activated protein kinase and not signal transducer and activator of transcription 3.
Molecular endocrinology (Baltimore, Md.) 2002;16(12):2902-12.
2002: Keiko Miyoshi; Barbara Meyer; Peter Gruss; Yongzhi Cui; Jean-Pierre Renou; Fanta Morgan; Gilbert H Smith; Moshe Reichenstein; Moshe Shani; Lothar Hennighausen; Gertraud W Robinson
Mammary epithelial cells are not able to undergo pregnancy-dependent differentiation in the absence of the helix-loop-helix inhibitor Id2.
Molecular endocrinology (Baltimore, Md.) 2002;16(12):2892-901.
2002: Joëlle Dupont; Jean-Pierre Renou; Moshe Shani; Lothar Hennighausen; Derek LeRoith
PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium.
The Journal of clinical investigation 2002;110(6):815-25.
2002: Marta I Gallego; Philip A Beachy; Lothar Hennighausen; Gertraud W Robinson
Differential requirements for shh in mammary tissue and hair follicle morphogenesis.
Developmental biology 2002;249(1):131-9.
2002: Robin Humphreys; Brian Bierie; Ling Zhao; Regina Raz; David Levy; Lothar Hennighausen
Deletion of Stat3 blocks mammary gland involution and extends functional competence of the secretory epithelium in the absence of lactogenic stimuli.
Endocrinology 2002;143(9):3641-50.
2002: Keiko Miyoshi; Andrea Rosner; Masahiro Nozawa; Christopher Byrd; Fanta Morgan; Esther Landesman-Bollag; Xin Xu; David C Seldin; Emmett V Schmidt; Makoto M Taketo; Gertraud W Robinson; Robert Cardiff; Lothar Hennighausen
Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors.
Oncogene 2002;21(36):5548-56.
2002: Jonathan Shillingford; Keiko Miyoshi; Michael Flagella; Gary E Shull; Lothar Hennighausen
Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis.
Molecular endocrinology (Baltimore, Md.) 2002;16(6):1309-21.
2002: Yongzhi Cui; Keiko Miyoshi; Estefania Claudio; Ulrich Siebenlist; Frank J Gonzalez; Jodi A Flaws; Kay-Uwe Wagner; Lothar Hennighausen
Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility.
The Journal of biological chemistry 2002;277(20):17830-5.
2002: Yu-An Yang; Binwu Tang; Gertraud Robinson; Lothar Hennighausen; Steven G Brodie; Chu-Xia Deng; Lalage M Wakefield
Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(3):123-30.
2002: Fabienne Le Provost; Gregory Riedlinger; Sun Hee Yim; Jamie Benedict; Frank J Gonzalez; Jodi A Flaws; Lothar Hennighausen
The aryl hydrocarbon receptor (AhR) and its nuclear translocator (Arnt) are dispensable for normal mammary gland development but are required for fertility.
Genesis (New York, N.Y. : 2000) 2002;32(3):231-9.
2002: Kay-Uwe Wagner; Corinne A Boulanger; MaLinda D Henry; Magdalene K Sgagias; Lothar Hennighausen; Gilbert H Smith
An adjunct mammary epithelial cell population in parous females: its role in functional adaptation and tissue renewal.
Development (Cambridge, England) 2002;129(6):1377-86.
2002: Jonathan Shillingford; Keiko Miyoshi; Gertraud W Robinson; Sandra L Grimm; Jeffrey M Rosen; Hans Neubauer; Klaus Pfeffer; Lothar Hennighausen
Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium.
Molecular endocrinology (Baltimore, Md.) 2002;16(3):563-70.
2002: Yiping Wu; Shoshana Yakar; Ling Zhao; Lothar Hennighausen; Derek LeRoith
Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis.
Cancer research 2002;62(4):1030-5.
2002: Gregory Riedlinger; Ryugo Okagaki; Kay-Uwe Wagner; Edmund B Rucker; Takami Oka; Keiko Miyoshi; Jodi A Flaws; Lothar Hennighausen
Bcl-x is not required for maintenance of follicles and corpus luteum in the postnatal mouse ovary.
Biology of reproduction 2002;66(2):438-44.
2002: Keiko Miyoshi; Jonathan Shillingford; Fabienne Le Provost; Fotini Gounari; Roderick Bronson; Harald von Boehmer; Makoto M Taketo; Robert Cardiff; Lothar Hennighausen; Khashayarsha Khazaie
Activation of beta -catenin signaling in differentiated mammary secretory cells induces transdifferentiation into epidermis and squamous metaplasias.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):219-24.
2001: Kay-Uwe Wagner; K McAllister; T Ward; B Davis; R Wiseman; Lothar Hennighausen
Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice.
Transgenic research 2001;10(6):545-53.
2001: Yongzhi Cui; M Li; KD Walton; K Sun; John Hanover; Priscilla A Furth; Lothar Hennighausen
The Stat3/5 locus encodes novel endoplasmic reticulum and helicase-like proteins that are preferentially expressed in normal and neoplastic mammary tissue.
Genomics 2001;78(3):129-34.
2001: KD Walton; Kay-Uwe Wagner; Edmund B Rucker; Jonathan Shillingford; Keiko Miyoshi; Lothar Hennighausen
Conditional deletion of the bcl-x gene from mouse mammary epithelium results in accelerated apoptosis during involution but does not compromise cell function during lactation.
Mechanisms of development 2001;109(2):281-93.
2001: Keiko Miyoshi; Jonathan Shillingford; Gilbert H Smith; S L Grimm; Kay-Uwe Wagner; Takami Oka; J M Rosen; Gertraud W Robinson; Lothar Hennighausen
Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium.
The Journal of cell biology 2001;155(4):531-42.
2001: Jonathan Shillingford; Lothar Hennighausen
Experimental mouse genetics-- answering fundamental questions about mammary gland biology.
Trends in endocrinology and metabolism: TEM 2001;12(9):402-8.
2001: Gertraud W Robinson; Kay-Uwe Wagner; Lothar Hennighausen
Functional mammary gland development and oncogene-induced tumor formation are not affected by the absence of the retinoblastoma gene.
Oncogene 2001;20(48):7115-9.
2001: Keiko Miyoshi; Yongzhi Cui; Gregory Riedlinger; P Robinson; Jessica A Lehoczky; L Zon; Takami Oka; Ken Dewar; Lothar Hennighausen
Structure of the mouse Stat 3/5 locus: evolution from Drosophila to zebrafish to mouse.
Genomics 2001;71(2):150-5.
2001: Marta I Gallego; N Binart; Gertraud W Robinson; Ryugo Okagaki; Karen T Coschigano; J Perry; J J Kopchick; Takami Oka; P A Kelly; Lothar Hennighausen
Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects.
Developmental biology 2001;229(1):163-75.
2000: Kay-Uwe Wagner; Estefania Claudio; Edmund B Rucker; Gregory Riedlinger; Christine Broussard; Pamela L Schwartzberg; Ulrich Siebenlist; Lothar Hennighausen
Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly.
Development (Cambridge, England) 2000;127(22):4949-58.
2000: Edmund B Rucker; P Dierisseau; Kay-Uwe Wagner; L Garrett; A Wynshaw-Boris; Jodi A Flaws; Lothar Hennighausen
Bcl-x and Bax regulate mouse primordial germ cell survival and apoptosis during embryogenesis.
Molecular endocrinology (Baltimore, Md.) 2000;14(7):1038-52.
2000: Gertraud W Robinson; Lothar Hennighausen; Peter F Johnson
Side-branching in the mammary gland: the progesterone-Wnt connection.
Genes & development 2000;14(8):889-94.
2000: Robin Humphreys; Lothar Hennighausen
Transforming growth factor alpha and mouse models of human breast cancer.
Oncogene 2000;19(8):1085-91.
2000: Lothar Hennighausen
Mouse models for breast cancer.
Oncogene 2000;19(8):966-7.
1999: Robin Humphreys; Lothar Hennighausen
Signal transducer and activator of transcription 5a influences mammary epithelial cell survival and tumorigenesis.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(10):685-94.
1999: S S Stegalkina; A Guerrero; KD Walton; Xibao Liu; Gertraud W Robinson; Lothar Hennighausen
Transcription originating in the long terminal repeats of the endogenous mouse mammary tumor virus MTV-3 is activated in Stat5a-null mice and picks Up hitchhiking exons.
Journal of virology 1999;73(10):8669-76.
1999: Xiaoling Xu; Kay-Uwe Wagner; D Larson; Z Weaver; Cuiling Li; Thomas Ried; Lothar Hennighausen; Anthony Wynshaw-Boris; Chu-Xia Deng
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation.
Nature genetics 1999;22(1):37-43.
1999: Soo-Hee Park; X Liu; Lothar Hennighausen; Helen W Davey; David J Waxman
Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.
The Journal of biological chemistry 1999;274(11):7421-30.
1999: Kay-Uwe Wagner; P Dierisseau; Lothar Hennighausen
Assignment of the murine tumor susceptibility gene 101 (tsg101) and a processed tsg101 pseudogene (tsg101-ps1) to mouse chromosome 7 band B5 and chromosome 15 band D1 by in situ hybridization.
Cytogenetics and cell genetics 1999;84(1-2):87-8.
1998: Kay-Uwe Wagner; P Dierisseau; Edmund B Rucker; Gertraud W Robinson; Lothar Hennighausen
Genomic architecture and transcriptional activation of the mouse and human tumor susceptibility gene TSG101: common types of shorter transcripts are true alternative splice variants.
Oncogene 1998;17(21):2761-70.
1998: Xibao Liu; Marta I Gallego; Gilbert H Smith; Gertraud W Robinson; Lothar Hennighausen
Functional rescue of Stat5a-null mammary tissue through the activation of compensating signals including Stat5b.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(9):795-803.
1998: Gertraud W Robinson; Peter F Johnson; Lothar Hennighausen; Esta Sterneck
The C/EBPbeta transcription factor regulates epithelial cell proliferation and differentiation in the mammary gland.
Genes & development 1998;12(12):1907-16.
1998: Lothar Hennighausen; Gertraud W Robinson
Think globally, act locally: the making of a mouse mammary gland.
Genes & development 1998;12(4):449-55.
1997: Kay-Uwe Wagner; W Scott Young; X Liu; Edward I Ginns; M Li; Priscilla A Furth; Lothar Hennighausen
Oxytocin and milk removal are required for post-partum mammary-gland development.
Genes and function 1997;1(4):233-44.
1997: Lothar Hennighausen; Gertraud W Robinson; Kay-Uwe Wagner; X Liu
Developing a mammary gland is a stat affair.
Journal of mammary gland biology and neoplasia 1997;2(4):365-72.
1997: Lothar Hennighausen
Molecular mechanisms of hormone controlled gene expression in the breast.
Molecular biology reports 1997;24(3):169-74.
1997: Gertraud W Robinson; Lothar Hennighausen
Inhibins and activins regulate mammary epithelial cell differentiation through mesenchymal-epithelial interactions.
Development (Cambridge, England) 1997;124(14):2701-8.
1997: Lothar Hennighausen; Gertraud W Robinson; Kay-Uwe Wagner; W Liu
Prolactin signaling in mammary gland development.
The Journal of biological chemistry 1997;272(12):7567-9.
1996: S A Oakes; Fabio Candotti; JA Johnston; Y Q Chen; John J Ryan; N Taylor; Xibao Liu; Lothar Hennighausen; Luigi D Notarangelo; William Paul; R. Michael Blaese; John O'Shea
Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.
Immunity 1996;5(6):605-15.
1996: Xibao Liu; Gertraud W Robinson; Lothar Hennighausen
Activation of Stat5a and Stat5b by tyrosine phosphorylation is tightly linked to mammary gland differentiation.
Molecular endocrinology (Baltimore, Md.) 1996;10(12):1496-506.
1996: W Scott Young; E Shepard; J Amico; Lothar Hennighausen; Kay-Uwe Wagner; Mary E LaMarca; CE McKinney; Edward I Ginns
Deficiency in mouse oxytocin prevents milk ejection, but not fertility or parturition.
Journal of neuroendocrinology 1996;8(11):847-53.
1996: D Ewald; M Li; S Efrat; G Auer; Robert J Wall; Priscilla A Furth; Lothar Hennighausen
Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen.
Science (New York, N.Y.) 1996;273(5280):1384-6.
1996: R A McKnight; M Spencer; Robert J Wall; Lothar Hennighausen
Severe position effects imposed on a 1 kb mouse whey acidic protein gene promoter are overcome by heterologous matrix attachment regions.
Molecular reproduction and development 1996;44(2):179-84.
1996: Gertraud W Robinson; Gilbert H Smith; D Gallahan; A Zimmer; Priscilla A Furth; Lothar Hennighausen
Understanding mammary gland development through the imbalanced expression of growth regulators.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;206(2):159-68.
1996: K Heermeier; MA Benedict; M Li; Priscilla A Furth; Gabriel Nuñez; Lothar Hennighausen
Bax and Bcl-xs are induced at the onset of apoptosis in involuting mammary epithelial cells.
Mechanisms of development 1996;56(1-2):197-207.
1996: D Gallahan; C Jhappan; G Robinson; Lothar Hennighausen; Richard Sharp; E Kordon; Robert Callahan; Glenn Merlino; Gilbert H Smith
Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
Cancer research 1996;56(8):1775-85.
1996: Ming-Wen Li; J Hu; K Heermeier; Lothar Hennighausen; Priscilla A Furth
Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(1):13-20.
1996: Ming-Wen Li; J Hu; K Heermeier; Lothar Hennighausen; Priscilla A Furth
Expression of a viral oncoprotein during mammary gland development alters cell fate and function: induction of p53-independent apoptosis is followed by impaired milk protein production in surviving cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(1):3-11.
1996: Robert J Wall; Caird E Rexroad; A Powell; A Shamay; R McKnight; Lothar Hennighausen
Synthesis and secretion of the mouse whey acidic protein in transgenic sheep.
Transgenic research 1996;5(1):67-72.
1995: Lothar Hennighausen; Robert J Wall; U Tillmann; M Li; Priscilla A Furth
Conditional gene expression in secretory tissues and skin of transgenic mice using the MMTV-LTR and the tetracycline responsive system.
Journal of cellular biochemistry 1995;59(4):463-72.
1995: Xibao Liu; Gertraud W Robinson; F Gouilleux; B Groner; Lothar Hennighausen
Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8831-5.
1995: Gertraud W Robinson; R A McKnight; Gilbert H Smith; Lothar Hennighausen
Mammary epithelial cells undergo secretory differentiation in cycling virgins but require pregnancy for the establishment of terminal differentiation.
Development (Cambridge, England) 1995;121(7):2079-90.
1995: R A McKnight; M Spencer; Jürgen Dittmer; John N Brady; Robert J Wall; Lothar Hennighausen
An Ets site in the whey acidic protein gene promoter mediates transcriptional activation in the mammary gland of pregnant mice but is dispensable during lactation.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):717-24.
1995: Priscilla A Furth; A Shamay; Lothar Hennighausen
Gene transfer into mammalian cells by jet injection.
Hybridoma 1995;14(2):149-52.
1995: E C Kordon; R A McKnight; C Jhappan; Lothar Hennighausen; Glenn Merlino; Gilbert H Smith
Ectopic TGF beta 1 expression in the secretory mammary epithelium induces early senescence of the epithelial stem cell population.
Developmental biology 1995;168(1):47-61.
1995: R A McKnight; Robert J Wall; Lothar Hennighausen
Expression of genomic and cDNA transgenes after co-integration in transgenic mice.
Transgenic research 1995;4(1):39-43.
1994: Priscilla A Furth; L St Onge; H Böger; Peter Gruss; Manfred Gossen; A Kistner; Hermann Bujard; Lothar Hennighausen
Temporal control of gene expression in transgenic mice by a tetracycline-responsive promoter.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9302-6.
1994: Lothar Hennighausen; R McKnight; T Burdon; M Baik; Robert J Wall; Gilbert H Smith
Whey acidic protein extrinsically expressed from the mouse mammary tumor virus long terminal repeat results in hyperplasia of the coagulation gland epithelium and impaired mammary development.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(6):607-13.
1993: C Jhappan; A G Geiser; E C Kordon; D Bagheri; Lothar Hennighausen; A B Roberts; Gilbert H Smith; Glenn Merlino
Targeting expression of a transforming growth factor beta 1 transgene to the pregnant mammary gland inhibits alveolar development and lactation.
The EMBO journal 1993;12(5):1835-45.
1992: Priscilla A Furth; A Shamay; Robert J Wall; Lothar Hennighausen
Gene transfer into somatic tissues by jet injection.
Analytical biochemistry 1992;205(2):365-8.
1992: R A McKnight; A Shamay; L Sankaran; Robert J Wall; Lothar Hennighausen
Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(15):6943-7.
1992: Lothar Hennighausen
The prospects for domesticating milk protein genes.
Journal of cellular biochemistry 1992;49(4):325-32.
1992: A Shamay; Vernon Pursel; E Wilkinson; Robert J Wall; Lothar Hennighausen
Expression of the whey acidic protein in transgenic pigs impairs mammary development.
Transgenic research 1992;1(3):124-32.
1992: A Shamay; Vernon Pursel; Robert J Wall; Lothar Hennighausen
Induction of lactogenesis in transgenic virgin pigs: evidence for gene and integration site-specific hormonal regulation.
Molecular endocrinology (Baltimore, Md.) 1992;6(2):191-7.
1991: T Burdon; Robert J Wall; A Shamay; Gilbert H Smith; Lothar Hennighausen
Over-expression of an endogenous milk protein gene in transgenic mice is associated with impaired mammary alveolar development and a milchlos phenotype.
Mechanisms of development 1991;36(1-2):67-74.
1991: Priscilla A Furth; Lothar Hennighausen; C Baker; B Beatty; R Woychick
The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice.
Nucleic acids research 1991;19(22):6205-8.
1991: A Shamay; S Solinas; Vernon Pursel; R A McKnight; L Alexander; Craig Warren Beattie; Lothar Hennighausen; Robert J Wall
Production of the mouse whey acidic protein in transgenic pigs during lactation.
Journal of animal science 1991;69(11):4552-62.
1991: H H Niller; Lothar Hennighausen
Formation of several specific nucleoprotein complexes on the human cytomegalovirus immediate early enhancer.
Nucleic acids research 1991;19(13):3715-21.
1991: T Burdon; L Sankaran; Robert J Wall; M Spencer; Lothar Hennighausen
Expression of a whey acidic protein transgene during mammary development. Evidence for different mechanisms of regulation during pregnancy and lactation.
The Journal of biological chemistry 1991;266(11):6909-14.
1991: Robert J Wall; Vernon Pursel; A Shamay; R A McKnight; C W Pittius; Lothar Hennighausen
High-level synthesis of a heterologous milk protein in the mammary glands of transgenic swine.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(5):1696-700.
1991: Lothar Hennighausen; C Westphal; L Sankaran; C W Pittius
Regulation of expression of genes for milk proteins.
Biotechnology (Reading, Mass.) 1991;16():65-74.
1990: H H Niller; Lothar Hennighausen
Phytohemagglutinin-induced activity of cyclic AMP (cAMP) response elements from cytomegalovirus is reduced by cyclosporine and synergistically enhanced by cAMP.
Journal of virology 1990;64(5):2388-91.
1990: Priscilla A Furth; H Westphal; Lothar Hennighausen
Expression from the HIV-LTR is stimulated by glucocorticoids and pregnancy.
AIDS research and human retroviruses 1990;6(4):553-60.
1989: Lothar Hennighausen; Priscilla A Furth; C W Pittius
kappa B elements strongly activate gene expression in non-lymphoid cells and function synergistically with NF1 elements.
Nucleic acids research 1989;17(20):8197-206.
1989: H Lubon; C W Pittius; Lothar Hennighausen
In vitro transcription of the mouse whey acidic protein promoter is affected by upstream sequences.
FEBS letters 1989;251(1-2):173-6.
1989: H Lubon; P Ghazal; Lothar Hennighausen; C Reynolds-Kohler; C Lockshin; Jay A Nelson
Cell-specific activity of the modulator region in the human cytomegalovirus major immediate-early gene.
Molecular and cellular biology 1989;9(3):1342-5.
1988: H Lubon; Lothar Hennighausen
Conserved region of the rat alpha-lactalbumin promoter is a target site for protein binding in vitro.
The Biochemical journal 1988;256(2):391-6.
1988: C W Pittius; L Sankaran; Y J Topper; Lothar Hennighausen
Comparison of the regulation of the whey acidic protein gene with that of a hybrid gene containing the whey acidic protein gene promoter in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1988;2(11):1027-32.
1988: H Lubon; P Ghazal; Jay A Nelson; Lothar Hennighausen
Cell-specific activity of the human immunodeficiency virus enhancer repeat in vitro.
AIDS research and human retroviruses 1988;4(5):381-91.
1988: C W Pittius; Lothar Hennighausen; E Lee; Heiner Westphal; E Nicols; J Vitale; K Gordon
A milk protein gene promoter directs the expression of human tissue plasminogen activator cDNA to the mammary gland in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(16):5874-8.
1988: P Ghazal; H Lubon; Lothar Hennighausen
Multiple sequence-specific transcription factors modulate cytomegalovirus enhancer activity in vitro.
Molecular and cellular biology 1988;8(4):1809-11.
1988: P Ghazal; H Lubon; Lothar Hennighausen
Specific interactions between transcription factors and the promoter-regulatory region of the human cytomegalovirus major immediate-early gene.
Journal of virology 1988;62(3):1076-9.
1987: P Ghazal; H Lubon; Bernhard Fleckenstein; Lothar Hennighausen
Binding of transcription factors and creation of a large nucleoprotein complex on the human cytomegalovirus enhancer.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(11):3658-62.
1987: C G Prosser; L Sankaran; Lothar Hennighausen; Y J Topper
Comparison of the roles of insulin and insulin-like growth factor I in casein gene expression and in the development of alpha-lactalbumin and glucose transport activities in the mouse mammary epithelial cell.
Endocrinology 1987;120(4):1411-6.