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Kenneth Hensley

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Chemicals & Drugs

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Biji T Kurien; Andrew Porter; Yaser Dorri; Saqib Iqbal; Anil D'Souza; Anil Singh; Sima Asfa; Marc Cartellieri; Kristen Mathias; Hiroyuki Matsumoto; Michael Bachmann; Kenneth Hensley; R Hal Scofield
Degree of modification of Ro60 by the lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren syndrome or systemic lupus erythematosus in BALB/c mice.
Kenneth Hensley; Alexandar Christov; Shekhar Kamat; X Cai Zhang; Kenneth W Jackson; Stephen Snow; Jan Post
Proteomic identification of binding partners for the brain metabolite lanthionine ketimine (LK) and documentation of LK effects on microglia and motoneuron cell cultures.
Gary W Arendash; April A Cox; Takashi Mori; Jennifer R Cracchiolo; Kenneth Hensley; L Jackson Roberts
Oxygen treatment triggers cognitive impairment in Alzheimer's transgenic mice.

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2011: Biji T Kurien; Andrew Porter; Yaser Dorri; Saqib Iqbal; Anil D'Souza; Anil Singh; Sima Asfa; Marc Cartellieri; Kristen Mathias; Hiroyuki Matsumoto; Michael Bachmann; Kenneth Hensley; R Hal Scofield
Degree of modification of Ro60 by the lipid peroxidation by-product 4-hydroxy-2-nonenal may differentially induce Sjögren syndrome or systemic lupus erythematosus in BALB/c mice.
Free radical biology & medicine 2011;50(10):1222-33.
2010: Kenneth Hensley; Alexandar Christov; Shekhar Kamat; X Cai Zhang; Kenneth W Jackson; Stephen Snow; Jan Post
Proteomic identification of binding partners for the brain metabolite lanthionine ketimine (LK) and documentation of LK effects on microglia and motoneuron cell cultures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(8):2979-88.
2009: Gary W Arendash; April A Cox; Takashi Mori; Jennifer R Cracchiolo; Kenneth Hensley; L Jackson Roberts
Oxygen treatment triggers cognitive impairment in Alzheimer's transgenic mice.
Neuroreport 2009;20(12):1087-92.
2009: Kenneth Hensley
The importance of getting a good start: gestational nutrition interacts with adult nutrition to affect function of the aging brain.
Neurobiology of disease 2009;35(1):1-2.
2009: Sandra E Gomez-Mejiba; Zili Zhai; Hammad Akram; Leesa J Deterding; Kenneth Hensley; Nataliya Smith; Rheal A Towner; Kenneth B Tomer; Ronald P Mason; Dario C Ramirez
Immuno-spin trapping of protein and DNA radicals: "tagging" free radicals to locate and understand the redox process.
Free radical biology & medicine 2009;46(7):853-65.
2009: Sandra E Gomez-Mejiba; Zili Zhai; Hammad Akram; Quentin N Pye; Kenneth Hensley; Biji T Kurien; R Hal Scofield; Dario C Ramirez
Inhalation of environmental stressors & chronic inflammation: autoimmunity and neurodegeneration.
Mutation research 2009;674(1-2):62-72.
2009: Kenneth Hensley
Detection of protein carbonyls by means of biotin hydrazide-streptavidin affinity methods.
Methods in molecular biology (Clifton, N.J.) 2009;536():457-62.
2008: Chandrashekhar D Kamat; Sunyana Gadal; Molina Mhatre; Kelly S Williamson; Quentin N Pye; Kenneth Hensley
Antioxidants in central nervous system diseases: preclinical promise and translational challenges.
Journal of Alzheimer's disease : JAD 2008;15(3):473-93.
2008: John Strong; Richard A Miller; Clinton M Astle; Robert A Floyd; Kevin Flurkey; Kenneth Hensley; Martin A Javors; Christiaan Leeuwenburgh; James Nelson; Ennio Ongini; Nancy L Nadon; Huber R Warner; David E Harrison
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice.
Aging cell 2008;7(5):641-50.
2008: Kelly S Williamson; J Brad Morris; Quentin N Pye; Chandrashekhar D Kamat; Kenneth Hensley
A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD.
Phytochemical analysis : PCA 2008;19(4):311-22.
2008: Anil D'Souza; Biji T Kurien; Rosalie Rodgers; Jaideep Shenoi; Sadamu Kurono; Hiroyuki Matsumoto; Kenneth Hensley; Swapan K Nath; R Hal Scofield
Detection of catalase as a major protein target of the lipid peroxidation product 4-HNE and the lack of its genetic association as a risk factor in SLE.
BMC medical genetics 2008;9():62.
2007: Richard A Miller; David E Harrison; Clinton M Astle; Robert A Floyd; Kevin Flurkey; Kenneth Hensley; Martin A Javors; Christiaan Leeuwenburgh; James Nelson; Ennio Ongini; Nancy L Nadon; Huber R Warner; John Strong
An Aging Interventions Testing Program: study design and interim report.
Aging cell 2007;6(4):565-75.
2007: Charlotte H Y Chung; Biji T Kurien; Padmaja Mehta; Molina Mhatre; Shenyun Mou; Quentin N Pye; Charles Stewart; Melinda West; Kelly S Williamson; Jan Post; Lucy Liu; Rachel Wang; Kenneth Hensley
Identification of lanthionine synthase C-like protein-1 as a prominent glutathione binding protein expressed in the mammalian central nervous system.
Biochemistry 2007;46(11):3262-9.
2006: Kenneth Hensley; Molina Mhatre; Shenyun Mou; Quentin N Pye; Charles Stewart; Melinda West; Kelly S Williamson
On the relation of oxidative stress to neuroinflammation: lessons learned from the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
Antioxidants & redox signaling 2006;8(11-12):2075-87.
2006: Biji T Kurien; Kenneth Hensley; Michael Bachmann; R Hal Scofield
Oxidatively modified autoantigens in autoimmune diseases.
Free radical biology & medicine 2006;41(4):549-56.
2006: Molina Mhatre; Kenneth Hensley; Albert Nguyen; Paula Grammas
Chronic thrombin exposure results in an increase in apolipoprotein-E levels.
Journal of neuroscience research 2006;84(2):444-9.
2006: Kenneth Hensley; Haitham Abdel-Moaty; Jerrod Hunter; Molina Mhatre; Shenyun Mou; Kim Nguyen; Tamara Potapova; Quentin N Pye; Min Qi; Heather Rice; Charles Stewart; Katharine Stroukoff; Melinda West
Primary glia expressing the G93A-SOD1 mutation present a neuroinflammatory phenotype and provide a cellular system for studies of glial inflammation.
Journal of neuroinflammation 2006;3():2.
2005: Wei-Xing Guo; Quentin N Pye; Kelly S Williamson; Charles A Stewart; Kenneth Hensley; Yashige Kotake; Robert A Floyd; Robert H Broyles
Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes.
Free radical biology & medicine 2005;39(5):641-50.
2005: H Fai Poon; Kenneth Hensley; Visith Thongboonkerd; Michael Merchant; Bert C Lynn; William M Pierce; Klein Jon; Vittorio Calabrese; D Allan Butterfield
Redox proteomics analysis of oxidatively modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis.
Free radical biology & medicine 2005;39(4):453-62.
2005: Scott J Salsman; Kenneth Hensley; Robert A Floyd
Sensitivity of protein tyrosine phosphatase activity to the redox environment, cytochrome C, and microperoxidase.
Antioxidants & redox signaling 2005;7(7-8):1078-88.
2005: Kenneth Hensley; Robert A Floyd
Oxidative modification of proteins in cell signaling.
Antioxidants & redox signaling 2005;7(5-6):523-5.
2005: Marzia Perluigi; H Fai Poon; Kenneth Hensley; William M Pierce; Klein Jon; Vittorio Calabrese; Carlo De Marco; D Allan Butterfield
Proteomic analysis of 4-hydroxy-2-nonenal-modified proteins in G93A-SOD1 transgenic mice--a model of familial amyotrophic lateral sclerosis.
Free radical biology & medicine 2005;38(7):960-8.
2005: R Hal Scofield; Biji T Kurien; Samantha Ganick; Micah T McClain; Quentin N Pye; Judith A James; Rebecca I Schneider; Robert H Broyles; Michael Bachmann; Kenneth Hensley
Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading.
Free radical biology & medicine 2005;38(6):719-28.
2005: M B Kadiiska; B C Gladen; D D Baird; D Germolec; L B Graham; Carol Parker; A Nyska; J T Wachsman; B N Ames; S Basu; N Brot; garret fitzgerald; R A Floyd; M George; J W Heinecke; G E Hatch; Kenneth Hensley; J A Lawson; Lawrence J Marnett; J D Morrow; D M Murray; J Plastaras; L J Roberts; J Rokach; M K Shigenaga; R S Sohal; J Sun; R R Tice; D H Van Thiel; D Wellner; Patrick B Walter; K B Tomer; R P Mason; J C Barrett
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?
Free radical biology & medicine 2005;38(6):698-710.
2005: Kenneth Hensley; Kelly S Williamson
HPLC-electrochemical detection of tocopherol products as indicators of reactive nitrogen intermediates.
Methods in enzymology 2005;396():171-82.
2004: Melinda West; Molina Mhatre; Alex Ceballos; Robert A Floyd; Paula Grammas; S Prasad Gabbita; Ladan Hamdheydari; Tammy Mai; Shenyun Mou; Quentin N Pye; Charles Stewart; Stuart West; Kelly S Williamson; Frank P Zemlan; Kenneth Hensley
The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice.
Journal of neurochemistry 2004;91(1):133-43.
2004: Wei-Xing Guo; Quentin N Pye; Kelly S Williamson; Charles A Stewart; Kenneth Hensley; Yashige Kotake; Robert A Floyd; Robert H Broyles
Reactive oxygen species in choline deficiency-induced apoptosis in rat hepatocytes.
Free radical biology & medicine 2004;37(7):1081-9.
2004: Paula Grammas; Ladan Hamdheydari; Elaine J Benaksas; Shenyun Mou; Quentin N Pye; William J Wechter; Robert A Floyd; Charles Stewart; Kenneth Hensley
Anti-inflammatory effects of tocopherol metabolites.
Biochemical and biophysical research communications 2004;319(3):1047-52.
2004: Biji T Kurien; Bradley W Pillow; Yaser Dorri; Kenneth Hensley; Michael Bachman; R Hal Scofield
SOD1 interacts directly with hemoglobin in vitro.
Thrombosis and haemostasis 2004;92(1):218-20.
2004: Molina Mhatre; Ravindar Pruthi; Kenneth Hensley; Frank A Holloway
5-HT3 antagonist ICS 205-930 enhances naltrexone's effects on ethanol intake.
European journal of pharmacology 2004;491(2-3):149-56.
2004: Molina Mhatre; Robert A Floyd; Kenneth Hensley
Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: common links and potential therapeutic targets.
Journal of Alzheimer's disease : JAD 2004;6(2):147-57.
2004: Kenneth Hensley; Elaine J Benaksas; Roberto Bolli; Philip C Comp; Paula Grammas; Ladan Hamdheydari; Shenyun Mou; Quentin N Pye; Marcus F Stoddard; Gemma L Wallis; Kelly S Williamson; Melinda West; William J Wechter; Robert A Floyd
New perspectives on vitamin E: gamma-tocopherol and carboxyelthylhydroxychroman metabolites in biology and medicine.
Free radical biology & medicine 2004;36(1):1-15.
2003: Ladan Hamdheydari; Alexander Christov; Todd Ottman; Kenneth Hensley; Paula Grammas
Oxidized LDLs affect nitric oxide and radical generation in brain endothelial cells.
Biochemical and biophysical research communications 2003;311(2):486-90.
2003: Kenneth Hensley; Joe Fedynyshyn; Scott Ferrell; Robert A Floyd; Brian Gordon; Paula Grammas; Ladan Hamdheydari; Molina Mhatre; Shenyun Mou; Quentin N Pye; Charles Stewart; Melinda West; Stuart West; Kelly S Williamson
Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis.
Neurobiology of disease 2003;14(1):74-80.
2003: Dai Nakae; Hideki Kishida; Tomonori Enami; Yoichi Konishi; Kenneth Hensley; Robert A Floyd; Yashige Kotake
Effects of phenyl N-tert-butyl nitrone and its derivatives on the early phase of hepatocarcinogenesis in rats fed a choline-deficient, L-amino acid-defined diet.
Cancer science 2003;94(1):26-31.
2002: Robert A Floyd; Kenneth Hensley
Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases.
Neurobiology of aging 2002;23(5):795-807.
2002: Anat Biegon; M Alvarado; Thomas F Budinger; Rachel Grossman; Kenneth Hensley; M S West; Yashige Kotake; M Ono; Robert A Floyd
Region-selective effects of neuroinflammation and antioxidant treatment on peripheral benzodiazepine receptors and NMDA receptors in the rat brain.
Journal of neurochemistry 2002;82(4):924-34.
2002: Kenneth Hensley; Robert A Floyd; Brian Gordon; Shenyun Mou; Quentin N Pye; Charles Stewart; Melinda West; Kelly Williamson
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis.
Journal of neurochemistry 2002;82(2):365-74.
2002: Robert A Floyd; Yashige Kotake; Kenneth Hensley; Dai Nakae; Yoichi Konishi
Reactive oxygen species in choline deficiency induced carcinogenesis and nitrone inhibition.
Molecular and cellular biochemistry 2002;234-235(1-2):195-203.
2002: Robert A Floyd; Kenneth Hensley; Michael J Forster; Judith A Kelleher-Andersson; Paul L Wood
Nitrones, their value as therapeutics and probes to understand aging.
Mechanisms of ageing and development 2002;123(8):1021-31.
2002: Robert A Floyd; Kenneth Hensley; Michael J Forster; Judith A Kelleher-Anderson; Paul L Wood
Nitrones as neuroprotectants and antiaging drugs.
Annals of the New York Academy of Sciences 2002;959():321-9.
2002: Kelly S Williamson; S Prasad Gabbita; Shenyun Mou; Melinda West; Quentin N Pye; William R Markesbery; Robert V Cooney; Paula Grammas; Ulrich Reimann-Philipp; Robert A Floyd; Kenneth Hensley
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2002;6(2):221-7.
2002: Kenneth Hensley; Robert A Floyd
Reactive oxygen species and protein oxidation in aging: a look back, a look ahead.
Archives of biochemistry and biophysics 2002;397(2):377-83.
2001: R A Floyd; M West; Kenneth Hensley
Oxidative biochemical markers; clues to understanding aging in long-lived species.
Experimental gerontology 2001;36(4-6):619-40.
2001: Scott J Salsman; N Felts; Quentin N Pye; Robert A Floyd; Kenneth Hensley
Induction of Akt phosphorylation in rat primary astrocytes by H2O2 occurs upstream of phosphatidylinositol 3-kinase: no evidence for oxidative inhibition of PTEN.
Archives of biochemistry and biophysics 2001;386(2):275-80.
2001: omid safa; Kenneth Hensley; Mikhail Smirnov; Charles T Esmon; Naomi L Esmon
Lipid oxidation enhances the function of activated protein C.
The Journal of biological chemistry 2001;276(3):1829-36.
2000: Kenneth Hensley; KA Robinson; S Prasad Gabbita; Scott J Salsman; Robert A Floyd
Reactive oxygen species, cell signaling, and cell injury.
Free radical biology & medicine 2000;28(10):1456-62.
2000: Kenneth Hensley; Yashige Kotake; Hong Sang; Quentin N Pye; Gemma L Wallis; L M Kolker; Tahereh Tabatabaie; Charles A Stewart; Yoichi Konishi; Dai Nakae; Robert A Floyd
Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria.
Carcinogenesis 2000;21(5):983-9.
2000: S Prasad Gabbita; KA Robinson; Charles A Stewart; Robert A Floyd; Kenneth Hensley
Redox regulatory mechanisms of cellular signal transduction.
Archives of biochemistry and biophysics 2000;376(1):1-13.
2000: Kenneth Hensley; KA Robinson; Quentin N Pye; Robert A Floyd; I Cheng; WA Garland; I Irwin
CPI-1189 inhibits interleukin 1beta-induced p38-mitogen-activated protein kinase phosphorylation: an explanation for its neuroprotective properties?
Neuroscience letters 2000;281(2-3):179-82.
2000: Kenneth Hensley; Kelly S Williamson; Robert A Floyd
Measurement of 3-nitrotyrosine and 5-nitro-gamma-tocopherol by high-performance liquid chromatography with electrochemical detection.
Free radical biology & medicine 2000;28(4):520-8.
2000: Robert A Floyd; Kenneth Hensley; G Bing
Evidence for enhanced neuro-inflammatory processes in neurodegenerative diseases and the action of nitrones as potential therapeutics.
Journal of neural transmission. Supplementum 2000;(60):387-414.
2000: Robert A Floyd; Kenneth Hensley
Nitrone inhibition of age-associated oxidative damage.
Annals of the New York Academy of Sciences 2000;899():222-37.
1999: KA Robinson; Charles A Stewart; Quentin N Pye; Robert A Floyd; Kenneth Hensley
Basal protein phosphorylation is decreased and phosphatase activity increased by an antioxidant and a free radical trap in primary rat glia.
Archives of biochemistry and biophysics 1999;365(2):211-5.
1999: Charles A Stewart; K Hyam; Gemma L Wallis; Hong Sang; KA Robinson; Robert A Floyd; Yashige Kotake; Kenneth Hensley
Phenyl-N-tert-butylnitrone demonstrates broad-spectrum inhibition of apoptosis-associated gene expression in endotoxin-treated rats.
Archives of biochemistry and biophysics 1999;365(1):71-4.
1999: Kenneth Hensley; Robert A Floyd; N Y Zheng; R Nael; KA Robinson; X Nguyen; Quentin N Pye; Charles A Stewart; James W Geddes; William R Markesbery; E Patel; Gail Johnson; G Bing
p38 kinase is activated in the Alzheimer's disease brain.
Journal of neurochemistry 1999;72(5):2053-8.
1999: KA Robinson; Charles A Stewart; Quentin N Pye; X Nguyen; L Kenney; S Salzman; Robert A Floyd; Kenneth Hensley
Redox-sensitive protein phosphatase activity regulates the phosphorylation state of p38 protein kinase in primary astrocyte culture.
Journal of neuroscience research 1999;55(6):724-32.
1999: Robert A Floyd; Kenneth Hensley; F Jaffery; L Maidt; K Robinson; Quentin N Pye; C Stewart
Increased oxidative stress brought on by pro-inflammatory cytokines in neurodegenerative processes and the protective role of nitrone-based free radical traps.
Life sciences 1999;65(18-19):1893-9.
1999: D Allan Butterfield; B Howard; SM Yatin; T Koppal; Jennifer Drake; Kenneth Hensley; Michael Y Aksenov; Marina V Aksenova; R Subramaniam; Sridhar Varadarajan; ME Harris-White; Norman W Pedigo; JM Carney
Elevated oxidative stress in models of normal brain aging and Alzheimer's disease.
Life sciences 1999;65(18-19):1883-92.
1998: Kenneth Hensley; Quentin N Pye; ML Maidt; Charles A Stewart; KA Robinson; F Jaffrey; Robert A Floyd
Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site.
Journal of neurochemistry 1998;71(6):2549-57.
1998: D Allan Butterfield; T Koppal; B Howard; R Subramaniam; N Hall; Kenneth Hensley; SM Yatin; K Allen; Michael Y Aksenov; Marina V Aksenova; J Carney
Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E.
Annals of the New York Academy of Sciences 1998;854():448-62.
1998: Dai Nakae; Yashige Kotake; Hideki Kishida; Kenneth Hensley; Ayumi Denda; Y Kobayashi; Wakashi Kitayama; Toshifumi Tsujiuchi; Hong Sang; Charles A Stewart; Tahereh Tabatabaie; Robert A Floyd; Yoichi Konishi
Inhibition by phenyl N-tert-butyl nitrone of early phase carcinogenesis in the livers of rats fed a choline-deficient, L-amino acid-defined diet.
Cancer research 1998;58(20):4548-51.
1998: Kenneth Hensley; ML Maidt; Z Yu; H Sang; William R Markesbery; Robert A Floyd
Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(20):8126-32.
1998: Annadora J Bruce-Keller; Jim G Begley; Weiming Fu; D Allan Butterfield; Dale E Bredesen; J B Hutchins; Kenneth Hensley; Mark P Mattson
Bcl-2 protects isolated plasma and mitochondrial membranes against lipid peroxidation induced by hydrogen peroxide and amyloid beta-peptide.
Journal of neurochemistry 1998;70(1):31-9.
1997: Kenneth Hensley; ML Maidt; Quentin N Pye; Charles A Stewart; M Wack; Tahereh Tabatabaie; Robert A Floyd
Quantitation of protein-bound 3-nitrotyrosine and 3,4-dihydroxyphenylalanine by high-performance liquid chromatography with electrochemical array detection.
Analytical biochemistry 1997;251(2):187-95.
1997: D Allan Butterfield; Kenneth Hensley; P Cole; R Subramaniam; Michael Y Aksenov; Marina V Aksenova; Paul M Bummer; BE Haley; JM Carney
Oxidatively induced structural alteration of glutamine synthetase assessed by analysis of spin label incorporation kinetics: relevance to Alzheimer's disease.
Journal of neurochemistry 1997;68(6):2451-7.
1997: Kenneth Hensley; Tahereh Tabatabaie; Charles A Stewart; Quentin N Pye; Robert A Floyd
Nitric oxide and derived species as toxic agents in stroke, AIDS dementia, and chronic neurodegenerative disorders.
Chemical research in toxicology 1997;10(5):527-32.
1997: S Prasad Gabbita; D Allan Butterfield; Kenneth Hensley; W Shaw; JM Carney
Aging and caloric restriction affect mitochondrial respiration and lipid membrane status: an electron paramagnetic resonance investigation.
Free radical biology & medicine 1997;23(2):191-201.
1997: Kenneth Hensley; JM Carney; Charles A Stewart; Tahereh Tabatabaie; Quentin N Pye; Robert A Floyd
Nitrone-based free radical traps as neuroprotective agents in cerebral ischaemia and other pathologies.
International review of neurobiology 1997;40():299-317.
1996: B J Howard; SM Yatin; Kenneth Hensley; K L Allen; J P Kelly; J Carney; D Allan Butterfield
Prevention of hyperoxia-induced alterations in synaptosomal membrane-associated proteins by N-tert-butyl-alpha-phenylnitrone and 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl (Tempol).
Journal of neurochemistry 1996;67(5):2045-50.
1996: William J Clerici; Kenneth Hensley; D L DiMartino; D Allan Butterfield
Direct detection of ototoxicant-induced reactive oxygen species generation in cochlear explants.
Hearing research 1996;98(1-2):116-24.
1996: M E Harris; Y Wang; Norman W Pedigo; Kenneth Hensley; D Allan Butterfield; JM Carney
Amyloid beta peptide (25-35) inhibits Na+-dependent glutamate uptake in rat hippocampal astrocyte cultures.
Journal of neurochemistry 1996;67(1):277-86.
1996: Kenneth Hensley; D Allan Butterfield; N Hall; P Cole; R Subramaniam; R Mark; Mark P Mattson; William R Markesbery; M E Harris; Michael Y Aksenov
Reactive oxygen species as causal agents in the neurotoxicity of the Alzheimer's disease-associated amyloid beta peptide.
Annals of the New York Academy of Sciences 1996;786():120-34.
1996: Michael Y Aksenov; Marina V Aksenova; D Allan Butterfield; Kenneth Hensley; C Vigo-Pelfrey; JM Carney
Glutamine synthetase-induced enhancement of beta-amyloid peptide A beta (1-40) neurotoxicity accompanied by abrogation of fibril formation and A beta fragmentation.
Journal of neurochemistry 1996;66(5):2050-6.
1996: D Allan Butterfield; L Martin; JM Carney; Kenneth Hensley
A beta (25-35) peptide displays H2O2-like reactivity towards aqueous Fe2+, nitroxide spin probes, and synaptosomal membrane proteins.
Life sciences 1996;58(3):217-28.
1995: Kenneth Hensley; N Hall; R Subramaniam; P Cole; M Harris; Michael Y Aksenov; Marina V Aksenova; S Prasad Gabbita; J F Wu; JM Carney
Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation.
Journal of neurochemistry 1995;65(5):2146-56.
1995: M E Harris; JM Carney; P S Cole; Kenneth Hensley; B J Howard; L Martin; Paul M Bummer; Y Wang; Norman W Pedigo; D Allan Butterfield
beta-Amyloid peptide-derived, oxygen-dependent free radicals inhibit glutamate uptake in cultured astrocytes: implications for Alzheimer's disease.
Neuroreport 1995;6(14):1875-9.
1995: Marina V Aksenova; M E Harris; Kenneth Hensley; D Allan Butterfield; JM Carney
Enhancement of beta-amyloid peptide A beta(1-40)-mediated neurotoxicity by glutamine synthetase.
Journal of neurochemistry 1995;65(4):1899-902.
1995: RJ Mark; Kenneth Hensley; D Allan Butterfield; Mark P Mattson
Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(9):6239-49.
1995: Kenneth Hensley; B J Howard; JM Carney; D Allan Butterfield
Membrane protein alterations in rodent erythrocytes and synaptosomes due to aging and hyperoxia.
Biochimica et biophysica acta 1995;1270(2-3):203-6.
1995: Kenneth Hensley; Marina V Aksenova; JM Carney; M Harris; D Allan Butterfield
Amyloid beta-peptide spin trapping. II: Evidence for decomposition of the PBN spin adduct.
Neuroreport 1995;6(3):493-6.
1995: Kenneth Hensley; Marina V Aksenova; JM Carney; M Harris; D Allan Butterfield
Amyloid beta-peptide spin trapping. I: Peptide enzyme toxicity is related to free radical spin trap reactivity.
Neuroreport 1995;6(3):489-92.
1995: M E Harris; Kenneth Hensley; D Allan Butterfield; R A Leedle; JM Carney
Direct evidence of oxidative injury produced by the Alzheimer's beta-amyloid peptide (1-40) in cultured hippocampal neurons.
Experimental neurology 1995;131(2):193-202.
1995: Kenneth Hensley; D Allan Butterfield; Mark P Mattson; Marina V Aksenova; M Harris; J F Wu; R Floyd; J Carney
A model for beta-amyloid aggregation and neurotoxicity based on the free radical generating capacity of the peptide: implications of "molecular shrapnel" for Alzheimer's disease.
Proceedings of the Western Pharmacology Society 1995;38():113-20.
1994: Kenneth Hensley; J Carney; N Hall; W Shaw; D Allan Butterfield
Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure.
Free radical biology & medicine 1994;17(4):321-31.
1994: D Allan Butterfield; Kenneth Hensley; M Harris; Mark P Mattson; J Carney
beta-Amyloid peptide free radical fragments initiate synaptosomal lipoperoxidation in a sequence-specific fashion: implications to Alzheimer's disease.
Biochemical and biophysical research communications 1994;200(2):710-5.
1994: Kenneth Hensley; JM Carney; Mark P Mattson; Marina V Aksenova; M Harris; J F Wu; R A Floyd; D Allan Butterfield
A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3270-4.
1993: D Allan Butterfield; Kenneth Hensley; N Hall; S Umhauer; J Carney
Interaction of tacrine and velnacrine with neocortical synaptosomal membranes: relevance to Alzheimer's disease.
Neurochemical research 1993;18(9):989-94.
1993: Kenneth Hensley; J Postlewaite; P Dobbs; D Allan Butterfield
Alteration of the erythrocyte membrane via enzymatic degradation of ankyrin (band 2.1): subcellular surgery characterized by EPR spectroscopy.
Biochimica et biophysica acta 1993;1145(2):205-11.
1991: Eliot Siegel; A W Templeton; Kenneth Hensley; M A McFadden; K G Baxter; Mark D Murphey; P E Cronin; R G Gesell; Samuel J Dwyer
Image data compression using a new floating-point digital signal processor.
Journal of digital imaging 1991;4(3):188-95.