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Meenhard Herlyn

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TOP 3
Adina Vultur; Meenhard Herlyn
SnapShot: Melanoma.
Rolf K Swoboda; Meenhard Herlyn
There is a world beyond protein mutations: the role of non-coding RNAs in melanomagenesis.
Katherine M Aird; Benjamin G Bitler; Azat Garipov; Meenhard Herlyn; Hua Li; Zhigang Tu; Stephan N Wagner; Zhi Wei; Hong Wu; Gao Zhang; Rugang Zhang
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.

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2013: Adina Vultur; Meenhard Herlyn
SnapShot: Melanoma.
Cancer cell 2013;23(5):706-706.e1.
2013: Rolf K Swoboda; Meenhard Herlyn
There is a world beyond protein mutations: the role of non-coding RNAs in melanomagenesis.
Experimental dermatology 2013;22(5):303-6.
2013: Katherine M Aird; Benjamin G Bitler; Azat Garipov; Meenhard Herlyn; Hua Li; Zhigang Tu; Stephan N Wagner; Zhi Wei; Hong Wu; Gao Zhang; Rugang Zhang
Suppression of nucleotide metabolism underlies the establishment and maintenance of oncogene-induced senescence.
Cell reports 2013;3(4):1252-65.
2013: Clemens Krepler; Mark McKinlay; Yasuhiro Mitsuuchi; Katherine L Nathanson; Eric M Neiman; Hubert Pehamberger; Jessie Villanueva; Adina Vultur; Min Xiao; Ravi K Amaravadi; Christopher Benetatos; Srinivas K Chunduru; Molly B Halloran; Xu He; Meenhard Herlyn
The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(7):1784-94.
2013: Tao Wang; Rajasekharan Somasundaram; Meenhard Herlyn
Combination therapy of immunocytokines with ipilimumab: a cure for melanoma?
The Journal of investigative dermatology 2013;133(3):595-6.
2013: Gregor M Balaburski; Neil Beeharry; Roland L Dunbrack; Donna L George; Seth Hayik; Meenhard Herlyn; Julia I-Ju Leu; Jessie Villanueva; Tim Yen; Gao Zhang; Mark D Andrake; Maureen E Murphy
A modified HSP70 inhibitor shows broad activity as an anticancer agent.
Molecular cancer research : MCR 2013;11(3):219-29.
2013: Brijal M Desai; Keith T Flaherty; Jun Kong; Clemens Krepler; Mercedes Lioni; Katherine L Nathanson; Thierry-Thien K Nguyen; Keiran Smalley; Jessie Villanueva; Adina Vultur; Min Xiao; Meenhard Herlyn
The anti-melanoma activity of dinaciclib, a cyclin-dependent kinase inhibitor, is dependent on p53 signaling.
PloS one 2013;8(3):e59588.
2013: Ling Li; Mizuho Fukunaga-Kalabis; Meenhard Herlyn
Isolation, characterization, and differentiation of human multipotent dermal stem cells.
Methods in molecular biology (Clifton, N.J.) 2013;989():235-46.
2013: Rajasekharan Somasundaram; Meenhard Herlyn
Relapse of melanoma after successful adoptive T-cell therapy: escape through inflammation-induced phenotypic melanoma cell plasticity.
Pigment cell & melanoma research 2013;26(1):2-4.
2012: Jobin K John; John M Koomen; Clemens Krepler; Rahel Mathew; Eric Meggers; Jane L Messina; Nicholas Pagano; Kim H T Paraiso; Vito W Rebecca; Ethan V Abel; Liliana P Cantini; Bin Fang; Meenhard Herlyn; Victoria Izumi; Keiran S M Smalley
GSK3β inhibition blocks melanoma cell/host interactions by downregulating N-cadherin expression and decreasing FAK phosphorylation.
The Journal of investigative dermatology 2012;132(12):2818-27.
2012: Mizuho Fukunaga-Kalabis; Meenhard Herlyn
Cancer: Complexion matters.
Nature 2012;491(7424):342-3.
2012: Mizuho Fukunaga-Kalabis; Meenhard Herlyn
Beyond ABC: another mechanism of drug resistance in melanoma side population.
The Journal of investigative dermatology 2012;132(10):2317-9.
2012: Xiangqian Kong; Zeng Li; Zhongjie Liang; Hong Liu; Shien Liu; Junyan Lu; Ronen Marmorstein; Jie Qin; Geena Rajan; Linjiang Tong; Adina Vultur; Mingyue Zheng; Weiliang Zhu; Enguang Feng; Meenhard Herlyn; Hualiang Jiang; Cheng Luo
Development of a novel class of B-Raf(V600E)-selective inhibitors through virtual screening and hierarchical hit optimization.
Organic & biomolecular chemistry 2012;10(36):7402-17.
2012: Young Chan Chae; Nika N Danial; Takehiko Dohi; Stefano Ferrero; Jagadish C Ghosh; Meenhard Herlyn; Lucia R Languino; Sofia Lisanti; Luigi Santambrogio; Valentina Vaira; Jessie Villanueva; Silvano Bosari; M Cecilia Caino; Dario C Altieri
Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.
Cancer cell 2012;22(3):331-44.
2012: Kati Räsänen; Meenhard Herlyn
Paracrine signaling between carcinoma cells and mesenchymal stem cells generates cancer stem cell niche via epithelial-mesenchymal transition.
Cancer discovery 2012;2(9):775-7.
2012: Gao Zhang; Meenhard Herlyn
Human nevi: no longer precursors of melanomas?
The Journal of investigative dermatology 2012;132(9):2133-4.
2012: Simon J Furney; Jarle Hakas; Meenhard Herlyn; Iwanka Kozarewa; Maryou B K Lambros; christopher Lord; Alan Mackay; Costas Mitsopoulos; Hiroshi Murata; Jorge S Reis-Filho; Gerda Ricken; Samra Turajlic; Marketa Zvelebil; Alan Ashworth; Kerry Fenwick; Richard Marais
Genomic characterisation of acral melanoma cell lines.
Pigment cell & melanoma research 2012;25(4):488-92.
2012: Tao Wang; Zhi Wei; Min Xiao; Xiaowei Xu; Gao Zhang; Rikka Azuma; Yingbin Ge; Meenhard Herlyn; Alfonso Lopez-Coral; Frank J Rauscher; Rajasekharan Somasundaram; Russel E Kaufman
Melanoma-derived conditioned media efficiently induce the differentiation of monocytes to macrophages that display a highly invasive gene signature.
Pigment cell & melanoma research 2012;25(4):493-505.
2012: Vera Wenzel; Diana Gabriel; Leslie B Gordon; Meenhard Herlyn; Johannes Ring; Daniela Roedl; Reinhard Schneider; Karima Djabali
Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo.
Biology open 2012;1(6):516-26.
2012: Jie Qin; Christian Ventocilla; Adina Vultur; Jeffrey Winkler; Peng Xie; Guoqiang Zhou; Quan Chen; Meenhard Herlyn; Qin Liu; Ronen Marmorstein
Identification of a novel family of BRAF(V600E) inhibitors.
Journal of medicinal chemistry 2012;55(11):5220-30.
2012: Rajasekharan Somasundaram; Meenhard Herlyn
Melanoma exosomes: messengers of metastasis.
Nature medicine 2012;18(6):853-4.
2012: Alice Pinc; Rajasekharan Somasundaram; Georg Stingl; Christine Wagner; Wolfgang Bauer; Patrick Brunner; Katharina Grabmeier-Pfistershammer; Melanie Gschaider; Meenhard Herlyn; Marcus Hörmann; Mei-Yu Hsu; Ahmad Jalili; Georgios Karanikas; Chiou-Yan Lai; Stephan N Wagner
Targeting CD20 in melanoma patients at high risk of disease recurrence.
Molecular therapy : the journal of the American Society of Gene Therapy 2012;20(5):1056-62.
2012: Ana Slipicevic; Meenhard Herlyn
Narrowing the knowledge gaps for melanoma.
Upsala journal of medical sciences 2012;117(2):237-43.
2012: Meenhard Herlyn
New dream team for melanoma therapy.
Pigment cell & melanoma research 2012;25(2):279-80.
2012: Adam Schayowitz; Lynn Schuchter; Jessie Villanueva; Adina Vultur; Wei Xu; Gordon H Yu; James Cotton; Meenhard Herlyn; Emiko Jeffries; Clemens Krepler; Timothy Schatz; Greg Bertenshaw; Douglas P Clark
Functional profiling of live melanoma samples using a novel automated platform.
PloS one 2012;7(12):e52760.
2012: Rajasekharan Somasundaram; Jessie Villanueva; Meenhard Herlyn
Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations.
Advances in pharmacology (San Diego, Calif.) 2012;65():335-59.
2012: Nicole Facompre; Meenhard Herlyn; Hiroshi Nakagawa; Devraj Basu
Stem-like cells and therapy resistance in squamous cell carcinomas.
Advances in pharmacology (San Diego, Calif.) 2012;65():235-65.
2012: Julia Tchou; Celine Satija; Louise C Showe; Lisa Chang; Meenhard Herlyn; Andrew V Kossenkov; Ellen Puré
Human breast cancer associated fibroblasts exhibit subtype specific gene expression profiles.
BMC medical genomics 2012;5():39.
2012: Seiji Naganuma; Mitsuteru Natsuizaka; Shinya Ohashi; Ben Rhoades; Harry Subramanian; Kelly A Whelan; Sanders Chang; J Alan Diehl; Phyllis A Gimotty; Meenhard Herlyn; Hiroshi Itoh; Shingo Kagawa; Hideaki Kinugasa; Andres J Klein-Szanto; Hiroshi Nakagawa
Notch receptor inhibition reveals the importance of cyclin D1 and Wnt signaling in invasive esophageal squamous cell carcinoma.
American journal of cancer research 2012;2(4):459-75.
2012: Ling Li; Mizuho Fukunaga-Kalabis; Meenhard Herlyn
Isolation and cultivation of dermal stem cells that differentiate into functional epidermal melanocytes.
Methods in molecular biology (Clifton, N.J.) 2012;806():15-29.
2011: Edward H Flach; Meenhard Herlyn; Vito W Rebecca; Keiran S M Smalley; Alexander R A Anderson
Fibroblasts contribute to melanoma tumor growth and drug resistance.
Molecular pharmaceutics 2011;8(6):2039-49.
2011: Jessie Villanueva; Adina Vultur; Meenhard Herlyn
Resistance to BRAF inhibitors: unraveling mechanisms and future treatment options.
Cancer research 2011;71(23):7137-40.
2011: Susan E Zabierowski; Nadia Dahmane; Valerie Baubet; Nadia Dahamne; Mizuho Fukunaga-Kalabis; Phyllis Gimotty; Matt Guerra; Benjamin Himes; Ling Li; Ronan McDaid; Sonal Patel; Meenhard Herlyn
Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor.
Stem cells (Dayton, Ohio) 2011;29(11):1752-62.
2011: Shinya Ohashi; Momo Nakagawa; Mitsuteru Natsuizaka; Devraj Basu; Douglas S Darling; J Alan Diehl; Phyllis A Gimotty; Meenhard Herlyn; Hiroshi Itoh; Shingo Kagawa; Ross A Kalman; Sotai Kimura; Andres J Klein-Szanto; Seiji Naganuma; Hiroshi Nakagawa
A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.
Cancer research 2011;71(21):6836-47.
2011: Meenhard Herlyn; Jessie Villanueva
Sorting through the many opportunities for melanoma therapy.
Pigment cell & melanoma research 2011;24(5):975-7.
2011: A E Thurber; S E Zabierowski; G Douglas; E Hacker; Meenhard Herlyn; J Helen Leonard; S N Ramakrishnan; Darren J Smit; E C Sturm; Richard A Sturm
Inverse expression states of the BRN2 and MITF transcription factors in melanoma spheres and tumour xenografts regulate the NOTCH pathway.
Oncogene 2011;30(27):3036-48.
2011: Devraj Basu; J Alan Diehl; Phyllis A Gimotty; Rachel Hammond; John T Lee; Kathleen T Montone; Kati Rasanen; Anil K Rustgi; Li-Ping Wang; Gregory S Weinstein; Meenhard Herlyn
Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas.
Cell cycle (Georgetown, Tex.) 2011;10(12):2008-16.
2011: Susan E Zabierowski; Mizuho Fukunaga-Kalabis; Ling Li; Meenhard Herlyn
Dermis-derived stem cells: a source of epidermal melanocytes and melanoma?
Pigment cell & melanoma research 2011;24(3):422-9.
2011: Rajasekharan Somasundaram; Jessie Villanueva; Meenhard Herlyn
Will engineered T cells expressing CD20 scFv eradicate Melanoma?
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(4):638-40.
2011: Adina Vultur; Jessie Villanueva; Meenhard Herlyn
Targeting BRAF in advanced melanoma: a first step toward manageable disease.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(7):1658-63.
2011: Ling Li; Mizuho Fukunaga-Kalabis; Meenhard Herlyn
The three-dimensional human skin reconstruct model: a tool to study normal skin and melanoma progression.
Journal of visualized experiments : JoVE 2011;(54):.
2010: Jessie Villanueva; Adina Vultur; John T Lee; Rajasekharan Somasundaram; Mizuho Fukunaga-Kalabis; Angela K Cipolla; Bradley Wubbenhorst; Xiaowei Xu; Phyllis A Gimotty; Damien Kee; Ademi E Santiago-Walker; Richard Letrero; Kurt D'Andrea; Anitha Pushparajan; James E Hayden; Kimberly Dahlman Brown; Sylvie Laquerre; Grant A McArthur; Jeffrey A Sosman; Katherine L Nathanson; Meenhard Herlyn
Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K.
Cancer cell 2010;18(6):683-95.
2010: Meenhard Herlyn; Katherine L Nathanson
Taking the guesswork out of uveal melanoma.
The New England journal of medicine 2010;363(23):2256-7.
2010: Mee-Jung Han; Huan Wang; Lynn A Beer; Hsin-Yao Tang; Meenhard Herlyn; David W Speicher
A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling.
Proteomics 2010;10(24):4450-62.
2010: Meenhard Herlyn
Boris Bastian.
Pigment cell & melanoma research 2010;23(6):834.
2010: John T Lee; Ling Li; Patricia A Brafford; Marcia van den Eijnden; Molly B Halloran; Katrin Sproesser; Nikolas K Haass; Keiran Smalley; James Tsai; Gideon Bollag; Meenhard Herlyn
PLX4032, a potent inhibitor of the B-Raf V600E oncogene, selectively inhibits V600E-positive melanomas.
Pigment cell & melanoma research 2010;23(6):820-7.
2010: Shinya Ohashi; Mitsuteru Natsuizaka; Yumi Yashiro-ohtani; Ross A Kalman; Momo Nakagawa; Lizi Wu; Andres Klein-Szanto; Meenhard Herlyn; J Alan Diehl; Jonathan P Katz; Warren S Pear; John T Seykora; Hiroshi Nakagawa
NOTCH1 and NOTCH3 coordinate esophageal squamous differentiation through a CSL-dependent transcriptional network.
Gastroenterology 2010;139(6):2113-23.
2010: M Fukunaga-Kalabis; G Martinez; Thiennga K Nguyen; D Kim; A Santiago-Walker; A Roesch; Meenhard Herlyn
Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population.
Oncogene 2010;29(46):6115-24.
2010: Priya Aggarwal; Laura Pontano Vaites; Jong Kyong Kim; Hestia Mellert; Buddha Gurung; Hiroshi Nakagawa; Meenhard Herlyn; Xianxin Hua; Anil K Rustgi; Steven B McMahon; J Alan Diehl
Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase.
Cancer cell 2010;18(4):329-40.
2010: Adina Vultur; Jessie Villanueva; Meenhard Herlyn
BRAF inhibitor unveils its potential against advanced melanoma.
Cancer cell 2010;18(4):301-2.
2010: Ademi Santiago-Walker; Meenhard Herlyn
The ups and downs of transcription factors in melanoma.
Journal of the National Cancer Institute 2010;102(15):1103-4.
2010: Mitsuteru Natsuizaka; Shinya Ohashi; Gabrielle S Wong; Azal Ahmadi; Ross A Kalman; Daniela Budo; Andres J P Klein-Szanto; Meenhard Herlyn; J Alan Diehl; Hiroshi Nakagawa
Insulin-like growth factor-binding protein-3 promotes transforming growth factor-{beta}1-mediated epithelial-to-mesenchymal transition and motility in transformed human esophageal cells.
Carcinogenesis 2010;31(8):1344-53.
2010: Carmen Z Michaylira; Gabrielle S Wong; Charles G Miller; Christie M Gutierrez; Hiroshi Nakagawa; Rachel Hammond; Andres Klein-Szanto; Ju-Seog Lee; Sang Bae Kim; Meenhard Herlyn; J Alan Diehl; Phyllis Gimotty; Anil K Rustgi
Periostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor-invasive signature in esophageal cancer.
Cancer research 2010;70(13):5281-92.
2010: Katharine D Grugan; Charles G Miller; Yao Yao; Carmen Z Michaylira; Shinya Ohashi; Andres J P Klein-Szanto; J Alan Diehl; Meenhard Herlyn; May Han; Hiroshi Nakagawa; Anil K Rustgi
Fibroblast-secreted hepatocyte growth factor plays a functional role in esophageal squamous cell carcinoma invasion.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):11026-31.
2010: Shinya Ohashi; Mitsuteru Natsuizaka; Gabrielle S Wong; Carmen Z Michaylira; Katharine D Grugan; Douglas B Stairs; Jiri Kalabis; Maria E Vega; Ross A Kalman; Momo Nakagawa; Andres Klein-Szanto; Meenhard Herlyn; J Alan Diehl; Anil K Rustgi; Hiroshi Nakagawa
Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.
Cancer research 2010;70(10):4174-84.
2010: Alexander Roesch; Mizuho Fukunaga-Kalabis; Elizabeth C Schmidt; Susan E Zabierowski; Patricia Brafford; Adina Vultur; Devraj Basu; Phyllis Gimotty; Thomas Vogt; Meenhard Herlyn
A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth.
Cell 2010;141(4):583-94.
2010: Meenhard Herlyn; Mizuho Fukunaga-Kalabis
What is a good model for melanoma?
The Journal of investigative dermatology 2010;130(4):911-2.
2010: Ling Li; Mizuho Fukunaga-Kalabis; Hong Yu; Xiaowei Xu; Jun Kong; John T Lee; Meenhard Herlyn
Human dermal stem cells differentiate into functional epidermal melanocytes.
Journal of cell science 2010;123(Pt 6):853-60.
2010: Yan Degenhardt; Jia Huang; Joel Greshock; Galene Horiates; Katherine Nathanson; Xiaolu Yang; Meenhard Herlyn; Barbara Weber
Distinct MHC gene expression patterns during progression of melanoma.
Genes, chromosomes & cancer 2010;49(2):144-54.
2010: Thomas Bogenrieder; Meenhard Herlyn
The molecular pathology of cutaneous melanoma.
Cancer biomarkers : section A of Disease markers 2010;9(1-6):267-86.
2010: Susan E Zabierowski; Meenhard Herlyn
Embryonic stem cells as a model for studying melanocyte development.
Methods in molecular biology (Clifton, N.J.) 2010;584():301-16.
2009: Anna B Katz; Sundeep G Keswani; Mounira Habli; Foong Y Lim; Philip W Zoltick; Paola Midrio; Elliot D Kozin; Meenhard Herlyn; Timothy M Crombleholme
Placental gene transfer: transgene screening in mice for trophic effects on the placenta.
American journal of obstetrics and gynecology 2009;201(5):499.e1-8.
2009: Chelsea C Pinnix; John T Lee; Zhao-Jun Liu; Ronan McDaid; Klara Balint; Levi J Beverly; Patricia Brafford; Min Xiao; Benjamin Himes; Susan E Zabierowski; Yumi Yashiro-ohtani; Katherine L Nathanson; Ana Bengston; Pam Pollock; Ashani T Weeraratna; Brian J Nickoloff; Warren S Pear; Anthony John Capobianco; Meenhard Herlyn
Active Notch1 confers a transformed phenotype to primary human melanocytes.
Cancer research 2009;69(13):5312-20.
2009: Hong Yu; Ronan McDaid; John Lee; Patricia Possik; Ling Li; Suresh M Kumar; David E Elder; Patricia Van Belle; Phyllis A Gimotty; Matt Guerra; Rachel Hammond; Katherine L Nathanson; Maria Dalla Palma; Meenhard Herlyn; Xiaowei Xu
The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes.
The American journal of pathology 2009;174(6):2367-77.
2009: Meenhard Herlyn
Driving in the melanoma landscape.
Experimental dermatology 2009;18(6):506-8.
2009: Keiran S M Smalley; Meenhard Herlyn
Integrating tumor-initiating cells into the paradigm for melanoma targeted therapy.
International journal of cancer. Journal international du cancer 2009;124(6):1245-50.
2009: Devraj Basu; Meenhard Herlyn
Defining microenvironments within mouse models that enhance tumor aggressiveness.
Cancer biology & therapy 2009;8(4):380-1.
2009: Adina Vultur; Meenhard Herlyn
Cracking the system: melanoma complexity demands new therapeutic approaches.
Pigment cell & melanoma research 2009;22(1):4-5.
2009: Keiran Smalley; Min Xiao; J Villanueva; Thiennga K Nguyen; Keith T Flaherty; R Letrero; Patricia Van Belle; David E Elder; Y Wang; Katherine L Nathanson; Meenhard Herlyn
CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.
Oncogene 2009;28(1):85-94.
2009: A Santiago-Walker; Ling Li; Nikolas K Haass; Meenhard Herlyn
Melanocytes: from morphology to application.
Skin pharmacology and physiology 2009;22(2):114-21.
2009: Emmanuelle Passegué; Shahin Rafii; Meenhard Herlyn
Cancer stem cells are everywhere.
Nature medicine 2009;15(1):23.
2008: Mizuho Fukunaga-Kalabis; Ademi Santiago-Walker; Meenhard Herlyn
Matricellular proteins produced by melanocytes and melanomas: in search for functions.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2008;1(1):93-102.
2008: Jiri Kalabis; Kenji Oyama; Takaomi Okawa; Hiroshi Nakagawa; Carmen Z Michaylira; Douglas B Stairs; Jose-Luiz Figueiredo; Umar Mahmood; J Alan Diehl; Meenhard Herlyn; Anil K Rustgi
A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification.
The Journal of clinical investigation 2008;118(12):3860-9.
2008: Jiri Kalabis; Gang Li; Mizuho Fukunaga-Kalabis; Anil K Rustgi; Meenhard Herlyn
Endothelin-3 stimulates survival of goblet cells in organotypic cultures of fetal human colonic epithelium.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(6):G1182-9.
2008: Hideki Harada; Hiroshi Nakagawa; Munenori Takaoka; James Lee; Meenhard Herlyn; J Alan Diehl; Anil K Rustgi
Cleavage of MCM2 licensing protein fosters senescence in human keratinocytes.
Cell cycle (Georgetown, Tex.) 2008;7(22):3534-8.
2008: Keiran Smalley; Mercedes Lioni; Maurizia Dalla Palma; Min Xiao; Brijal Desai; Suzanne Egyhazi; Johan Hansson; Hong Wu; Alastair J King; Patricia Van Belle; David E Elder; Keith T Flaherty; Meenhard Herlyn; Katherine L Nathanson
Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas.
Molecular cancer therapeutics 2008;7(9):2876-83.
2008: Mercedes Lioni; Kazuhiro Noma; Andrew R Snyder; Andres Klein-Szanto; J Alan Diehl; Anil K Rustgi; Meenhard Herlyn; Keiran Smalley
Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.
Molecular cancer therapeutics 2008;7(9):2866-75.
2008: Jessie Villanueva; Meenhard Herlyn
Melanoma and the tumor microenvironment.
Current oncology reports 2008;10(5):439-46.
2008: Keiran Smalley; Rooha Contractor; Thiennga K Nguyen; Min Xiao; Robin Edwards; Viswanathan Muthusamy; Alastair J King; Keith T Flaherty; Marcus Bosenberg; Meenhard Herlyn; Katherine L Nathanson
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer research 2008;68(14):5743-52.
2008: Susan E Zabierowski; Meenhard Herlyn
Melanoma stem cells: the dark seed of melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(17):2890-4.
2008: John Lee; Patricia Brafford; Meenhard Herlyn
Unraveling the mysteries of IGF-1 signaling in melanoma.
The Journal of investigative dermatology 2008;128(6):1358-60.
2008: Kazuhiro Noma; Keiran S M Smalley; Mercedes Lioni; Yoshio Naomoto; Noriaki Tanaka; Wafik S El-Deiry; Alastair J King; Hiroshi Nakagawa; Meenhard Herlyn
The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis.
Gastroenterology 2008;134(7):1981-93.
2008: Peng Xie; Douglas S Williams; G Ekin Atilla-Gokcumen; Leslie Milk; Min Xiao; Keiran S M Smalley; Meenhard Herlyn; Eric Meggers; Ronen Marmorstein
Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity.
ACS chemical biology 2008;3(5):305-16.
2008: Randall W Alfano; Stephen H Leppla; Shihui Liu; Thomas H Bugge; Meenhard Herlyn; Keiran S Smalley; Jennifer L Bromberg-White; Nicholas S Duesbery; Arthur E Frankel
Cytotoxicity of the matrix metalloproteinase-activated anthrax lethal toxin is dependent on gelatinase expression and B-RAF status in human melanoma cells.
Molecular cancer therapeutics 2008;7(5):1218-26.
2008: Luca Sigalotti; Alessia Covre; Susan Zabierowski; Benjamin Himes; Francesca Colizzi; Pier Giorgio Natali; Meenhard Herlyn; Michele Maio
Cancer testis antigens in human melanoma stem cells: expression, distribution, and methylation status.
Journal of cellular physiology 2008;215(2):287-91.
2008: M Fukunaga-Kalabis; G Martinez; S M Telson; Zhao-Jun Liu; Klara Balint; I Juhasz; David E Elder; Bernard Perbal; Meenhard Herlyn
Downregulation of CCN3 expression as a potential mechanism for melanoma progression.
Oncogene 2008;27(18):2552-60.
2008: Susan E Zabierowski; Meenhard Herlyn
Learning the ABCs of melanoma-initiating cells.
Cancer cell 2008;13(3):185-7.
2008: Silvia Zecchini; Marco Bianchi; Nicoletta Colombo; Roberta Fasani; Giovanni Goisis; Chiara Casadio; Giuseppe Viale; Jinsong Liu; Meenhard Herlyn; Andrew K Godwin; Paolo Giovanni Nuciforo; Ugo Cavallaro
The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium.
Cancer research 2008;68(4):1110-8.
2008: William M Lin; Alissa C Baker; Rameen Beroukhim; Wendy Winckler; Whei Feng; Jennifer M Marmion; Elisabeth Laine; Heidi Greulich; Hsiuyi Tseng; Casey Gates; F Stephen Hodi; Glenn Dranoff; William R Sellers; Roman K Thomas; Matthew Meyerson; Todd R Golub; Reinhard Dummer; Meenhard Herlyn; Gad Getz; Levi A Garraway
Modeling genomic diversity and tumor dependency in malignant melanoma.
Cancer research 2008;68(3):664-73.
2008: Mee-Jung Han; Meenhard Herlyn; Aron B Fisher; David W Speicher
Microscale solution IEF combined with 2-D DIGE substantially enhances analysis depth of complex proteomes such as mammalian cell and tissue extracts.
Electrophoresis 2008;29(3):695-705.
2008: Keiran Sm Smalley; Nikolas K Haass; Mercedes Lioni; Kazuhiro Noma; Meenhard Herlyn
In vitro three-dimensional tumor microenvironment models for anticancer drug discovery.
Expert opinion on drug discovery 2008;3(1):1-10.
2008: Jasna Maksimoska; Douglas S Williams; G Ekin Atilla-Gokcumen; Keiran S M Smalley; Patrick J Carroll; Richard D Webster; Panagis Filippakopoulos; Stefan Knapp; Meenhard Herlyn; Eric Meggers
Similar biological activities of two isostructural ruthenium and osmium complexes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(16):4816-22.
2008: Devraj Basu; Meenhard Herlyn
Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy.
Cancer biology & therapy 2008;7(1):151-2.
2008: Nikolas K Haass; Katrin Sproesser; Thiennga K Nguyen; Rooha Contractor; C Angelica Medina; Katherine L Nathanson; Meenhard Herlyn; Keiran Smalley
The mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor AZD6244 (ARRY-142886) induces growth arrest in melanoma cells and tumor regression when combined with docetaxel.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):230-9.
2008: Ashley Gordon; Elliott D Kozin; Sundeep G Keswani; Sachin S Vaikunth; Anna B Katz; Philip W Zoltick; Michele Favata; Antoneta P Radu; Louis J Soslowsky; Meenhard Herlyn; Timothy M Crombleholme
Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2008;16(1):70-9.
2007: Meenhard Herlyn; Ruth Halaban; Ze'ev Ronai; Lynn Schuchter; Marianne Berwick; Daniel Pinkel
Roadmap for new opportunities in melanoma research.
Seminars in oncology 2007;34(6):566-76.
2007: Chelsea C Pinnix; Meenhard Herlyn
The many faces of Notch signaling in skin-derived cells.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2007;20(6):458-65.
2007: John Lee; Meenhard Herlyn
Old disease, new culprit: tumor stem cells in cancer.
Journal of cellular physiology 2007;213(3):603-9.
2007: Takaomi Okawa; Carmen Z Michaylira; Jiri Kalabis; Douglas B Stairs; Hiroshi Nakagawa; Claudia D Andl; Cameron N Johnstone; Andres J P Klein-Szanto; Wafik S El-Deiry; Edna Cukierman; Meenhard Herlyn; Anil K Rustgi
The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation.
Genes & development 2007;21(21):2788-803.
2007: Mizuho Fukunaga-Kalabis; Meenhard Herlyn
Unraveling mysteries of the multifunctional protein SPARC.
The Journal of investigative dermatology 2007;127(11):2497-8.
2007: K G Suresh Kumar; Jianghuai Liu; Ying Li; Duonan Yu; Andrei Thomas-Tikhonenko; Meenhard Herlyn; Serge Y Fuchs
Raf inhibitor stabilizes receptor for the type I interferon but inhibits its anti-proliferative effects in human malignant melanoma cells.
Cancer biology & therapy 2007;6(9):1437-41.
2007: Cynthia Spittle; M Renee Ward; Katherine L Nathanson; Phyllis A Gimotty; Eric Rappaport; Marcia S Brose; Angelica Medina; Richard Letrero; Meenhard Herlyn; Robin H Edwards
Application of a BRAF pyrosequencing assay for mutation detection and copy number analysis in malignant melanoma.
The Journal of molecular diagnostics : JMD 2007;9(4):464-71.
2007: Himabindu Gaddipati; Meenhard Herlyn
Association of polymorphisms of FAS-1377, FAS-670, and FASL-844 genes with risk factors for cutaneous malignant melanoma.
Cancer journal (Sudbury, Mass.) 2007;13(4):226-8.
2007: John Lee; Meenhard Herlyn
Microenvironmental influences in melanoma progression.
Journal of cellular biochemistry 2007;101(4):862-72.
2007: Friedegund Meier; S Busch; Konstantinos G Lasithiotakis; D Kulms; Claus Garbe; Evelyn Maczey; Meenhard Herlyn; Birgit Schittek
Combined targeting of MAPK and AKT signalling pathways is a promising strategy for melanoma treatment.
The British journal of dermatology 2007;156(6):1204-13.
2007: Pablo Lopez Bergami; Conway Huang; James S Goydos; Dana Yip; Menashe Bar-Eli; Meenhard Herlyn; Keiran Smalley; Alka Mahale; Alexey Eroshkin; Stuart Aaronson; Ze'ev Ronai
Rewired ERK-JNK signaling pathways in melanoma.
Cancer cell 2007;11(5):447-60.
2007: Hannes Seidl; Erika Richtig; Hemma Tilz; Martina Stefan; Ulrike Schmidbauer; Martin Asslaber; Kurt Zatloukal; Meenhard Herlyn; Helmut Schaider
Profiles of chemokine receptors in melanocytic lesions: de novo expression of CXCR6 in melanoma.
Human pathology 2007;38(5):768-80.
2007: Kenji Oyama; Takaomi Okawa; Hiroshi Nakagawa; Munenori Takaoka; Claudia D Andl; Seok-Hyun Kim; Andres Klein-Szanto; J Alan Diehl; Meenhard Herlyn; Wafik S El-Deiry; Anil K Rustgi
AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.
Oncogene 2007;26(16):2353-64.
2007: Suresh M Kumar; Hong Yu; Robin Edwards; Lianjun Chen; Steven Kazianis; Patricia Brafford; Geza Acs; Meenhard Herlyn; Xiaowei Xu
Mutant V600E BRAF increases hypoxia inducible factor-1alpha expression in melanoma.
Cancer research 2007;67(7):3177-84.
2007: Jianghuai Liu; K G Suresh Kumar; Duonan Yu; S A Molton; M McMahon; Meenhard Herlyn; Andrei Thomas-Tikhonenko; Serge Y Fuchs
Oncogenic BRAF regulates beta-Trcp expression and NF-kappaB activity in human melanoma cells.
Oncogene 2007;26(13):1954-8.
2007: Meenhard Herlyn
Farming cells to rebuild skin and melanoma.
Cancer biology & therapy 2007;6(3):467-71.
2007: Keiran Smalley; Rooha Contractor; Nikolas K Haass; John Lee; Katherine L Nathanson; C Angelina Medina; Keith T Flaherty; Meenhard Herlyn
Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.
British journal of cancer 2007;96(3):445-9.
2007: Mercedes Lioni; Patricia Brafford; Claudia D Andl; Anil K Rustgi; Wafik S El-Deiry; Meenhard Herlyn; Keiran Smalley
Dysregulation of claudin-7 leads to loss of E-cadherin expression and the increased invasion of esophageal squamous cell carcinoma cells.
The American journal of pathology 2007;170(2):709-21.
2007: Ann-Kathrin Wenke; Christian Kjellman; Evy Lundgren-Akerlund; Christian Uhlmann; Nikolas K Haass; Meenhard Herlyn; Anja Bosserhoff
Expression of integrin alpha10 is induced in malignant melanoma.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2007;29(5):373-86.
2007: Keiran Smalley; Rooha Contractor; Nikolas K Haass; Angela N Kulp; G Ekin Atilla-Gokcumen; Douglas S Williams; Howard Bregman; Keith T Flaherty; Maria S Soengas; Eric Meggers; Meenhard Herlyn
An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.
Cancer research 2007;67(1):209-17.
2006: Alastair J King; Denis R Patrick; Roberta S Batorsky; Maureen L Ho; Hieu T Do; Shu Yun Zhang; Rakesh Kumar; David W Rusnak; Andrew K Takle; David M Wilson; Erin Hugger; Lifu Wang; Florian Karreth; Julie C Lougheed; Jae Lee; David Chau; Thomas Stout; Earl W May; Cynthia M Rominger; Michael D Schaber; Lusong Luo; Ami S Lakdawala; Jerry L Adams; Rooha Contractor; Keiran Smalley; Meenhard Herlyn; Michael M Morrissey; David A Tuveson; Pearl S Huang
Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885.
Cancer research 2006;66(23):11100-5.
2006: Mizuho Fukunaga-Kalabis; Gabriela Martinez; Zhao-Jun Liu; Jiri Kalabis; Paul Mrass; Wolfgang Weninger; Sue M Firth; Nathalie Planque; Bernard Perbal; Meenhard Herlyn
CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.
The Journal of cell biology 2006;175(4):563-9.
2006: Claudia D Andl; Brenton B Fargnoli; Takaomi Okawa; Mark Bowser; Munenori Takaoka; Hiroshi Nakagawa; Andres Klein-Szanto; Xianxin Hua; Meenhard Herlyn; Anil K Rustgi
Coordinated functions of E-cadherin and transforming growth factor beta receptor II in vitro and in vivo.
Cancer research 2006;66(20):9878-85.
2006: Keiran Smalley; Mercedes Lioni; Meenhard Herlyn
Life isn't flat: taking cancer biology to the next dimension.
In vitro cellular & developmental biology. Animal 2006;42(8-9):242-7.
2006: David T Dicker; Jeremy Lerner; Patricia Van Belle; Stephen F Barth; DuPont Guerry; Meenhard Herlyn; David E Elder; Wafik S El-Deiry
Differentiation of normal skin and melanoma using high resolution hyperspectral imaging.
Cancer biology & therapy 2006;5(8):1033-8.
2006: John Lee; Meenhard Herlyn
Embryogenesis meets tumorigenesis.
Nature medicine 2006;12(8):882-4.
2006: Keith Hoek; Natalie Schlegel; Patricia Brafford; Antje Sucker; Selma Ugurel; Rajiv Kumar; Barbara L Weber; Katherine L Nathanson; David J Phillips; Meenhard Herlyn; Dirk Schadendorf; Reinhard Dummer
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2006;19(4):290-302.
2006: Tanja Spottl; Martin Hausmann; Manuela Gunckel; Hans Herfarth; Meenhard Herlyn; Juergen Schoelmerich; Gerhard Rogler
A new organotypic model to study cell interactions in the intestinal mucosa.
European journal of gastroenterology & hepatology 2006;18(8):901-9.
2006: Tanja Spoettl; Martin Hausmann; Meenhard Herlyn; Manuela Gunckel; A Dirmeier; Werner Falk; Hans Herfarth; Juergen Schoelmerich; Gerhard Rogler
Monocyte chemoattractant protein-1 (MCP-1) inhibits the intestinal-like differentiation of monocytes.
Clinical and experimental immunology 2006;145(1):190-9.
2006: Dong Fang; Kim Leishear; Thiennga K Nguyen; Rena Finko; Kun Cai; Mizuho Fukunaga; Ling Li; Patricia Brafford; Angela N Kulp; Xiaowei Xu; Keiran Smalley; Meenhard Herlyn
Defining the conditions for the generation of melanocytes from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2006;24(7):1668-77.
2006: Hong Yu; Dong Fang; Suresh M Kumar; Ling Li; Thiennga K Nguyen; Geza Acs; Meenhard Herlyn; Xiaowei Xu
Isolation of a novel population of multipotent adult stem cells from human hair follicles.
The American journal of pathology 2006;168(6):1879-88.
2006: Keiran Smalley; Nikolas K Haass; Patricia Brafford; Mercedes Lioni; Keith T Flaherty; Meenhard Herlyn
Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases.
Molecular cancer therapeutics 2006;5(5):1136-44.
2006: Michael L Cher; Dwight A Towler; Shahin Rafii; David Rowley; Henry J Donahue; Evan T Keller; Meenhard Herlyn; Eun Ah Cho; Leland W K Chung
Cancer interaction with the bone microenvironment: a workshop of the National Institutes of Health Tumor Microenvironment Study Section.
The American journal of pathology 2006;168(5):1405-12.
2006: Zhao-Jun Liu; Min Xiao; Klara Balint; Akinobu Soma; Chelsea C Pinnix; Anthony John Capobianco; Omaida Velazquez; Meenhard Herlyn
Inhibition of endothelial cell proliferation by Notch1 signaling is mediated by repressing MAPK and PI3K/Akt pathways and requires MAML1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):1009-11.
2006: Zhao-Jun Liu; Min Xiao; Klara Balint; Keiran Smalley; Patricia Brafford; Ruihua Qiu; Chelsea C Pinnix; Xueli Li; Meenhard Herlyn
Notch1 signaling promotes primary melanoma progression by activating mitogen-activated protein kinase/phosphatidylinositol 3-kinase-Akt pathways and up-regulating N-cadherin expression.
Cancer research 2006;66(8):4182-90.
2006: Keiran Smalley; Meenhard Herlyn
Towards the targeted therapy of melanoma.
Mini reviews in medicinal chemistry 2006;6(4):387-93.
2006: Masahiro Oka; Chikako Nishigori; Toshiro Kageshita; Mei-Yu Hsu; Sunita Penmatcha; Meenhard Herlyn
Expression of PKC isoforms in human melanocytic cells in situ.
Journal of dermatological science 2006;41(2):157-61.
2006: Meenhard Herlyn
Molecular targets in melanoma: strategies and challenges for diagnosis and therapy.
International journal of cancer. Journal international du cancer 2006;118(3):523-6.
2005: Keiran Smalley; Mercedes Lioni; Meenhard Herlyn
Targeting the stromal fibroblasts: a novel approach to melanoma therapy.
Expert review of anticancer therapy 2005;5(6):1069-78.
2005: Keiran Smalley; Patricia Brafford; Meenhard Herlyn
Selective evolutionary pressure from the tissue microenvironment drives tumor progression.
Seminars in cancer biology 2005;15(6):451-9.
2005: Keiran Smalley; Meenhard Herlyn
Targeting intracellular signaling pathways as a novel strategy in melanoma therapeutics.
Annals of the New York Academy of Sciences 2005;1059():16-25.
2005: Nikolas K Haass; Meenhard Herlyn
Normal human melanocyte homeostasis as a paradigm for understanding melanoma.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2005;10(2):153-63.
2005: Klara Balint; Min Xiao; Chelsea C Pinnix; Akinobu Soma; Imre Veres; Istvan Juhasz; Eric J Brown; Anthony John Capobianco; Meenhard Herlyn; Zhao-Jun Liu
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression.
The Journal of clinical investigation 2005;115(11):3166-76.
2005: Dong Fang; Thiennga K Nguyen; Kim Leishear; Rena Finko; Angela N Kulp; Susan Hotz; Patricia Van Belle; Xiaowei Xu; David E Elder; Meenhard Herlyn
A tumorigenic subpopulation with stem cell properties in melanomas.
Cancer research 2005;65(20):9328-37.
2005: Gang Li; Meenhard Herlyn
Information sharing and collateral damage.
Trends in molecular medicine 2005;11(8):350-2.
2005: Mei-Yu Hsu; Sherry A Rovinsky; Sunita Penmatcha; Meenhard Herlyn; Desirae Muirhead
Bone morphogenetic proteins in melanoma: angel or devil?
Cancer metastasis reviews 2005;24(2):251-63.
2005: Meenhard Herlyn
Metastatic melanoma cells. Introduction.
Cancer metastasis reviews 2005;24(2):193-4.
2005: Nikolas K Haass; Keiran Smalley; Ling Li; Meenhard Herlyn
Adhesion, migration and communication in melanocytes and melanoma.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2005;18(3):150-9.
2005: Linda McArdle; Mairin Rafferty; Kapaettu Satyamoorthy; G M Maelandsmo; Peter A Dervan; Meenhard Herlyn; David J Easty
Microarray analysis of phosphatase gene expression in human melanoma.
The British journal of dermatology 2005;152(5):925-30.
2005: Keiran Smalley; Patricia Brafford; Nikolas K Haass; Johanna M Brandner; Eric Brown; Meenhard Herlyn
Up-regulated expression of zonula occludens protein-1 in human melanoma associates with N-cadherin and contributes to invasion and adhesion.
The American journal of pathology 2005;166(5):1541-54.
2005: Tianqian Zhang; Rajasekharan Somasundaram; Klara Berencsi; Laura Caputo; Pyapalli Rani; DuPont Guerry; Emma E Furth; Barrett J Rollins; Mary E Putt; Phyllis A Gimotty; Rolf Swoboda; Meenhard Herlyn; Dorothee Herlyn
CXC chemokine ligand 12 (stromal cell-derived factor 1 alpha) and CXCR4-dependent migration of CTLs toward melanoma cells in organotypic culture.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(9):5856-63.
2005: Vassilis G Gorgoulis; Leandros-Vassilios F Vassiliou; Panagiotis Karakaidos; Panayotis Zacharatos; Athanassios Kotsinas; Triantafillos Liloglou; Monica Venere; Richard A DiTullio; Nikolaos G Kastrinakis; Brynn Levy; Dimitris Kletsas; Akihiro Yoneta; Meenhard Herlyn; Christos Kittas; Thanos D Halazonetis
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions.
Nature 2005;434(7035):907-13.
2005: Karen L Price; Meenhard Herlyn; Carolyn L Dent; Dirk R Gewert; Claire Linge
The prevalence of interferon-alpha transcription defects in malignant melanoma.
Melanoma research 2005;15(2):91-8.
2005: Suresh M Kumar; Geza Acs; Dong Fang; Meenhard Herlyn; David E Elder; Xiaowei Xu
Functional erythropoietin autocrine loop in melanoma.
The American journal of pathology 2005;166(3):823-30.
2005: Friedegund Meier; Birgit Schittek; Silke Busch; Claus Garbe; Keiran Smalley; Kapaettu Satyamoorthy; Gang Li; Meenhard Herlyn
The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma.
Frontiers in bioscience : a journal and virtual library 2005;10():2986-3001.
2005: Mei-Yu Hsu; Ling Li; Meenhard Herlyn
Cultivation of normal human epidermal melanocytes in the absence of phorbol esters.
Methods in molecular medicine 2005;107():13-28.
2004: David J Margolis; Timothy Cromblehome; Meenhard Herlyn; Philip Cross; Linda Weinberg; Jennifer Filip; Kathleen J Propert
Clinical protocol. Phase I trial to evaluate the safety of H5.020CMV.PDGF-b and limb compression bandage for the treatment of venous leg ulcer: trial A.
Human gene therapy 2004;15(10):1003-19.
2004: Keiran Smalley; Meenhard Herlyn
Loitering with intent: new evidence for the role of BRAF mutations in the proliferation of melanocytic lesions.
The Journal of investigative dermatology 2004;123(4):xvi-xvii.
2004: Jung-whan Kim; Christopher W Wong; Jeffrey D Goldsmith; Chun Song; Weili Fu; Mary-Beth Allion; Meenhard Herlyn; Abu-Bakr Al-Mehdi; Ruth J Muschel
Rapid apoptosis in the pulmonary vasculature distinguishes non-metastatic from metastatic melanoma cells.
Cancer letters 2004;213(2):203-12.
2004: Seok-Hyun Kim; Kunhong Kim; Jae G Kwagh; David T Dicker; Meenhard Herlyn; Anil K Rustgi; Youhai Chen; Wafik S El-Deiry
Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells.
The Journal of biological chemistry 2004;279(38):40044-52.
2004: Sundeep G Keswani; Anna B Katz; Foong-Yen Lim; Philip W Zoltick; Antoneta Radu; Datis Alaee; Meenhard Herlyn; Timothy M Crombleholme
Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2004;12(5):497-504.
2004: Lin Yang; Han C Dan; Mei Sun; Qiyuan Liu; Xiameng SUN; Richard I Feldman; Andrew D Hamilton; Mark A Polokoff; Santo V Nicosia; Meenhard Herlyn; Said M Sebti; Jin Q Cheng
Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt.
Cancer research 2004;64(13):4394-9.
2004: Ala-Eddin Al Moustafa; William D Foulkes; Annick Wong; Houda Jallal; Gerald Batist; Qunyan Yu; Meenhard Herlyn; Piotr Sicinski; Moulay A Alaoui-Jamali
Cyclin D1 is essential for neoplastic transformation induced by both E6/E7 and E6/E7/ErbB-2 cooperation in normal cells.
Oncogene 2004;23(30):5252-6.
2004: Gang Li; Mizuho Fukunaga; Meenhard Herlyn
Reversal of melanocytic malignancy by keratinocytes is an E-cadherin-mediated process overriding beta-catenin signaling.
Experimental cell research 2004;297(1):142-51.
2004: Léon C L van Kempen; Friedegund Meier; Mikala Egeblad; Monique J F Kersten-Niessen; Claus Garbe; Ulrich H Weidle; Goos N P van Muijen; Meenhard Herlyn; Henri P J Bloemers; Guido W M Swart
Truncation of activated leukocyte cell adhesion molecule: a gateway to melanoma metastasis.
The Journal of investigative dermatology 2004;122(5):1293-301.
2004: Robin H Edwards; M Renee Ward; H Wu; C Angelina Medina; Marcia S Brose; Patricia Volpe; S Nussen-Lee; H M Haupt; Anne-Marie Martin; Meenhard Herlyn; Stuart R Lessin; Barbara L Weber
Absence of BRAF mutations in UV-protected mucosal melanomas.
Journal of medical genetics 2004;41(4):270-2.
2004: Nikolas K Haass; Keiran Smalley; Meenhard Herlyn
The role of altered cell-cell communication in melanoma progression.
Journal of molecular histology 2004;35(3):309-18.
2004: Carola Berking; Richelle Takemoto; Kapaettu Satyamoorthy; Takahashi Shirakawa; Malihe Eskandarpour; Johan Hansson; Patricia A VanBelle; David E Elder; Meenhard Herlyn
Induction of melanoma phenotypes in human skin by growth factors and ultraviolet B.
Cancer research 2004;64(3):807-11.
2004: Cliff Perlis; Meenhard Herlyn
Recent advances in melanoma biology.
The oncologist 2004;9(2):182-7.
2003: Anthony L Cook; Philippe D Donatien; Aaron G Smith; Mark Murphy; Malcolm K Jones; Meenhard Herlyn; Dorothy C Bennett; J Helen Leonard; Richard A Sturm
Human melanoblasts in culture: expression of BRN2 and synergistic regulation by fibroblast growth factor-2, stem cell factor, and endothelin-3.
The Journal of investigative dermatology 2003;121(5):1150-9.
2003: Meenhard Herlyn; DuPont Guerry
First international melanoma research congress.
Cancer biology & therapy 2003;2(6):721-4.
2003: Gang Li; Jiri Kalabis; Xiaowei Xu; Friedegund Meier; Masahiro Oka; Thomas Bogenrieder; Meenhard Herlyn
Reciprocal regulation of MelCAM and AKT in human melanoma.
Oncogene 2003;22(44):6891-9.
2003: Dirk J Ruiter; Meenhard Herlyn
[Melanoma-stroma interactions and melanoma progression].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(10):773-6.
2003: Keiran Smalley; Meenhard Herlyn
The great escape: another way for melanoma to leave physiological control?
The Journal of investigative dermatology 2003;121(4):xi-xii.
2003: Zhao-Jun Liu; Ruthanne Snyder; Akinobu Soma; Takashi Shirakawa; Barry L Ziober; Ronald M Fairman; Meenhard Herlyn; Omaida Velazquez
VEGF-A and alphaVbeta3 integrin synergistically rescue angiogenesis via N-Ras and PI3-K signaling in human microvascular endothelial cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(13):1931-3.
2003: Thomas Bogenrieder; Meenhard Herlyn
Axis of evil: molecular mechanisms of cancer metastasis.
Oncogene 2003;22(42):6524-36.
2003: Jin H Song; doyoun song; Meenhard Herlyn; Kenneth C Petruk; Chunhai Hao
Cisplatin down-regulation of cellular Fas-associated death domain-like interleukin-1beta-converting enzyme-like inhibitory proteins to restore tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human melanoma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(11):4255-66.
2003: Sunil R Hingorani; Michael Jacobetz; Gavin P. Robertson; Meenhard Herlyn; David A Tuveson
Suppression of BRAF(V599E) in human melanoma abrogates transformation.
Cancer research 2003;63(17):5198-202.
2003: David A Tuveson; Barbara L Weber; Meenhard Herlyn
BRAF as a potential therapeutic target in melanoma and other malignancies.
Cancer cell 2003;4(2):95-8.
2003: Zhao-Jun Liu; Meenhard Herlyn
Slit-Robo: neuronal guides signal in tumor angiogenesis.
Cancer cell 2003;4(1):1-2.
2003: Friedegund Meier; Ulrich M Caroli; Kapaettu Satyamoorthy; Birgit Schittek; Jürgen Bauer; Carola Berking; Helga Möller; Evelyn Maczey; Gernot Rassner; Meenhard Herlyn; Claus Garbe
Fibroblast growth factor-2 but not Mel-CAM and/or beta3 integrin promotes progression of melanocytes to melanoma.
Experimental dermatology 2003;12(3):296-306.
2003: Francesco M Marincola; Ena Wang; Meenhard Herlyn; Barbara Seliger; Soldano Ferrone
Tumors as elusive targets of T-cell-based active immunotherapy.
Trends in immunology 2003;24(6):335-42.
2003: Jiri Kalabis; Michael J Patterson; Greg H Enders; Brigitte Marian; Renato V Iozzo; Gerhard Rogler; Phyllis A Gimotty; Meenhard Herlyn
Stimulation of human colonic epithelial cells by leukemia inhibitory factor is dependent on collagen-embedded fibroblasts in organotypic culture.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1115-7.
2003: Gang Li; Kapaettu Satyamoorthy; Friedegund Meier; Carola Berking; Thomas Bogenrieder; Meenhard Herlyn
Function and regulation of melanoma-stromal fibroblast interactions: when seeds meet soil.
Oncogene 2003;22(20):3162-71.
2003: Cheryl J A Hirst; Meenhard Herlyn; Peter A Cattini; Elissavet Kardami
High levels of CUG-initiated FGF-2 expression cause chromatin compaction, decreased cardiomyocyte mitosis, and cell death.
Molecular and cellular biochemistry 2003;246(1-2):111-6.
2003: Claus J Gruss; Kapaettu Satyamoorthy; Carola Berking; John Lininger; Mark Nesbit; Helmut Schaider; Zhao-Jun Liu; Masahiro Oka; Mei-Yu Hsu; Takashi Shirakawa; Gang Li; Thomas Bogenrieder; Peter Carmeliet; Wafik S El-Deiry; Stephen L Eck; Justi S Rao; Andrew H Baker; Jean T Bennet; Timothy M Crombleholme; Omaida Velazquez; Jagajan Karmacharya; David J Margolis; James M Wilson; Michael Detmar; Mihaela Skobe; Paul D Robbins; Clayton Buck; Meenhard Herlyn
Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice.
The Journal of investigative dermatology 2003;120(4):683-92.
2003: Kapaettu Satyamoorthy; Gang Li; Michelle R Gerrero; Marcia S Brose; Patricia Volpe; Barbara L Weber; Patricia Van Belle; David E Elder; Meenhard Herlyn
Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation.
Cancer research 2003;63(4):756-9.
2003: Helmut Schaider; Masahiro Oka; Thomas Bogenrieder; Mark Nesbit; Kapaettu Satyamoorthy; Carola Berking; Kouji Matsushima; Meenhard Herlyn
Differential response of primary and metastatic melanomas to neutrophils attracted by IL-8.
International journal of cancer. Journal international du cancer 2003;103(3):335-43.
2003: Claudia D Andl; Takaaki Mizushima; Hiroshi Nakagawa; Kenji Oyama; Hideki Harada; Katerina Chruma; Meenhard Herlyn; Anil K Rustgi
Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo.
The Journal of biological chemistry 2003;278(3):1824-30.
2003: Omaida Velazquez; Meenhard Herlyn
The vascular phenotype of melanoma metastasis.
Clinical & experimental metastasis 2003;20(3):229-35.
2003: Kapaettu Satyamoorthy; Meenhard Herlyn
p16INK4A and familial melanoma.
Methods in molecular biology (Clifton, N.J.) 2003;222():185-95.
2003: Zhao-Jun Liu; Takashi Shirakawa; Yan Li; Akinobu Soma; Masahiro Oka; G Paolo Dotto; Ronald M Fairman; Omaida Velazquez; Meenhard Herlyn
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis.
Molecular and cellular biology 2003;23(1):14-25.
2002: Mei-Yu Hsu; Friedegund Meier; Meenhard Herlyn
Melanoma development and progression: a conspiracy between tumor and host.
Differentiation; research in biological diversity 2002;70(9-10):522-36.
2002: Marcia S Brose; Patricia Volpe; Michael Feldman; Madhu Kumar; Irum Rishi; Renee Gerrero; Eugene Einhorn; Meenhard Herlyn; John D Minna; Andrew Nicholson; Jack A Roth; Steven M Albelda; Helen Davies; Charles Cox; Graham Brignell; Philip Stephens; P Andrew Futreal; Richard Wooster; Michael R Stratton; Barbara L Weber
BRAF and RAS mutations in human lung cancer and melanoma.
Cancer research 2002;62(23):6997-7000.
2002: Meenhard Herlyn; Martin Padarathsingh; Lynda Chin; Mary Hendrix; Dorothea Becker; Mark Nelson; Yves A DeClerck; James McCarthy; Suresh Mohla
New approaches to the biology of melanoma: a workshop of the National Institutes of Health Pathology B Study Section.
The American journal of pathology 2002;161(5):1949-57.
2002: Ie-Ming Shih; Mei-Yu Hsu; Robert J Oldt; Meenhard Herlyn; John D Gearhart; Robert J Kurman
The Role of E-cadherin in the Motility and Invasion of Implantation Site Intermediate Trophoblast.
Placenta 2002;23(10):706-15.
2002: Thomas Bogenrieder; Meenhard Herlyn
Cell-surface proteolysis, growth factor activation and intercellular communication in the progression of melanoma.
Critical reviews in oncology/hematology 2002;44(1):1-15.
2002: Kapaettu Satyamoorthy; Gang Li; Patricia Van Belle; David E Elder; Meenhard Herlyn
A versatile method for the removal of melanin from ribonucleic acids in melanocytic cells.
Melanoma research 2002;12(5):449-52.
2002: Edward R Sauter; Richelle Takemoto; Samuel Litwin; Meenhard Herlyn
p53 alone or in combination with antisense cyclin D1 induces apoptosis and reduces tumor size in human melanoma.
Cancer gene therapy 2002;9(10):807-12.
2002: Omaida Velazquez; Ruthanne Snyder; Zhao-Jun Liu; Ronald M Fairman; Meenhard Herlyn
Fibroblast-dependent differentiation of human microvascular endothelial cells into capillary-like 3-dimensional networks.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(10):1316-8.
2002: Ena Wang; Lance D Miller; Galen A Ohnmacht; Simone Mocellin; Ainhoa Perez-Diez; David Petersen; Yingdong Zhao; Richard Simon; John I Powell; Esther Asaki; H Richard Alexander; Paul H Duray; Meenhard Herlyn; Nicholas P Restifo; Edison Liu; STEVEN ROSENBERG; Francesco M Marincola
Prospective molecular profiling of melanoma metastases suggests classifiers of immune responsiveness.
Cancer research 2002;62(13):3581-6.
2002: Edward R Sauter; Un-Cheol Yeo; Andrea von Stemm; Weizhu Zhu; Samuel Litwin; David S Tichansky; Giuseppa Pistritto; Mark Nesbit; Daniel Pinkel; Meenhard Herlyn; Boris C Bastian
Cyclin D1 is a candidate oncogene in cutaneous melanoma.
Cancer research 2002;62(11):3200-6.
2002: Daniel S Samadi; Ian N Jacobs; Danielle Walsh; Sarah Bouchard; Meenhard Herlyn; Timothy M Crombleholme
Adenovirus-mediated ex vivo gene transfer of human vascular endothelial growth factor in a rabbit laryngotracheal reconstruction model.
The Annals of otology, rhinology, and laryngology 2002;111(4):295-301.
2002: Kapaettu Satyamoorthy; Gang Li; Bhavesh Vaidya; Jiri Kalabis; Meenhard Herlyn
Insulin-like growth factor-I-induced migration of melanoma cells is mediated by interleukin-8 induction.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2002;13(2):87-93.
2002: Meenhard Herlyn
Emerging concepts and technologies in melanoma research.
Melanoma research 2002;12(1):3-8.
2002: Gang Li; Kapaettu Satyamoorthy; Meenhard Herlyn
Dynamics of cell interactions and communications during melanoma development.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 2002;13(1):62-70.
2002: Dirk Ruiter; Thomas Bogenrieder; David E Elder; Meenhard Herlyn
Melanoma-stroma interactions: structural and functional aspects.
The lancet oncology 2002;3(1):35-43.
2002: Richard A Sturm; Kapaettu Satyamoorthy; Friedegund Meier; brooke gardiner; Darren J Smit; Bhavesh Vaidya; Meenhard Herlyn
Osteonectin/SPARC induction by ectopic beta(3) integrin in human radial growth phase primary melanoma cells.
Cancer research 2002;62(1):226-32.
2002: Carola Berking; Richelle Takemoto; Robert L Binder; Scott M Hartman; Dirk J Ruiter; Patricia M Gallagher; Stuart R Lessin; Meenhard Herlyn
Photocarcinogenesis in human adult skin grafts.
Carcinogenesis 2002;23(1):181-7.
2001: Gang Li; Helmut Schaider; Kapaettu Satyamoorthy; Y Hanakawa; K Hashimoto; Meenhard Herlyn
Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development.
Oncogene 2001;20(56):8125-35.
2001: Carola Berking; Richelle Takemoto; Helmut Schaider; Louise C Showe; Kapaettu Satyamoorthy; P Robbins; Meenhard Herlyn
Transforming growth factor-beta1 increases survival of human melanoma through stroma remodeling.
Cancer research 2001;61(22):8306-16.
2001: Linda McArdle; Mairin Rafferty; G M Maelandsmo; Orla E Bergin; C J Farr; Peter A Dervan; S O'Loughlin; Meenhard Herlyn; David J Easty
Protein tyrosine phosphatase genes downregulated in melanoma.
The Journal of investigative dermatology 2001;117(5):1255-60.
2001: Kapaettu Satyamoorthy; Gang Li; Bhavesh Vaidya; D Patel; Meenhard Herlyn
Insulin-like growth factor-1 induces survival and growth of biologically early melanoma cells through both the mitogen-activated protein kinase and beta-catenin pathways.
Cancer research 2001;61(19):7318-24.
2001: Mark Nesbit; Helmut Schaider; Carola Berking; D T Shih; Mei-Yu Hsu; M McBrian; Timothy M Crombleholme; Rosalie Elenitsas; C Buck; Meenhard Herlyn
Alpha5 and alpha2 integrin gene transfers mimic the PDGF-B-induced transformed phenotype of fibroblasts in human skin.
Laboratory investigation; a journal of technical methods and pathology 2001;81(9):1263-74.
2001: Kapaettu Satyamoorthy; J Muyrers; Friedegund Meier; D Patel; Meenhard Herlyn
Mel-CAM-specific genetic suppressor elements inhibit melanoma growth and invasion through loss of gap junctional communication.
Oncogene 2001;20(34):4676-84.
2001: Mark Nesbit; Helmut Schaider; T H Miller; Meenhard Herlyn
Low-level monocyte chemoattractant protein-1 stimulation of monocytes leads to tumor formation in nontumorigenic melanoma cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(11):6483-90.
2001: Joji Iida; Duanqing Pei; T Kang; Melanie A Simpson; Meenhard Herlyn; Leo T Furcht; James B McCarthy
Melanoma chondroitin sulfate proteoglycan regulates matrix metalloproteinase-dependent human melanoma invasion into type I collagen.
The Journal of biological chemistry 2001;276(22):18786-94.
2001: Gang Li; Kapaettu Satyamoorthy; Meenhard Herlyn
N-cadherin-mediated intercellular interactions promote survival and migration of melanoma cells.
Cancer research 2001;61(9):3819-25.
2001: Kapaettu Satyamoorthy; Thomas Bogenrieder; Meenhard Herlyn
No longer a molecular black box--new clues to apoptosis and drug resistance in melanoma.
Trends in molecular medicine 2001;7(5):191-4.
2001: Edward R Sauter; Mark Nesbit; David S Tichansky; Zhao-Jun Liu; T Shirakawa; J Palazzo; Meenhard Herlyn
Fibroblast growth factor-binding protein expression changes with disease progression in clinical and experimental human squamous epithelium.
International journal of cancer. Journal international du cancer 2001;92(3):374-81.
2001: Carola Berking; Meenhard Herlyn
Human skin reconstruct models: a new application for studies of melanocyte and melanoma biology.
Histology and histopathology 2001;16(2):669-74.
2001: Carola Berking; Richelle Takemoto; Kapaettu Satyamoorthy; Rosalie Elenitsas; Meenhard Herlyn
Basic fibroblast growth factor and ultraviolet B transform melanocytes in human skin.
The American journal of pathology 2001;158(3):943-53.
2001: C Berking; Meenhard Herlyn
Experimental induction of human atypical melanocytic lesions and melanoma in ultraviolet-irradiated human skin grafted to immunodeficient mice.
Methods in molecular medicine 2001;61():71-84.
2000: Kasirajan Ayyanathan; William Fredericks; Carola Berking; Meenhard Herlyn; C Balakrishnan; E Gunther; Frank J Rauscher
Hormone-dependent tumor regression in vivo by an inducible transcriptional repressor directed at the PAX3-FKHR oncogene.
Cancer research 2000;60(20):5803-14.
2000: Kapaettu Satyamoorthy; NH Chehab; M J Waterman; M C Lien; Wafik S El-Deiry; Meenhard Herlyn; Thanos D Halazonetis
Aberrant regulation and function of wild-type p53 in radioresistant melanoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2000;11(9):467-74.
2000: Meenhard Herlyn; Carola Berking; Gang Li; Kapaettu Satyamoorthy
Lessons from melanocyte development for understanding the biological events in naevus and melanoma formation.
Melanoma research 2000;10(4):303-12.
2000: William Fredericks; Kasirajan Ayyanathan; Meenhard Herlyn; JR Friedman; Frank J Rauscher
An engineered PAX3-KRAB transcriptional repressor inhibits the malignant phenotype of alveolar rhabdomyosarcoma cells harboring the endogenous PAX3-FKHR oncogene.
Molecular and cellular biology 2000;20(14):5019-31.
2000: Mei-Yu Hsu; Friedegund Meier; Mark Nesbit; JY Hsu; Patricia Van Belle; David E Elder; Meenhard Herlyn
E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors.
The American journal of pathology 2000;156(5):1515-25.
2000: Masahiro Oka; Carola Berking; Mark Nesbit; Kapaettu Satyamoorthy; Helmut Schaider; G Murphy; M Ichihashi; Edward R Sauter; Meenhard Herlyn
Interleukin-8 overexpression is present in pyoderma gangrenosum ulcers and leads to ulcer formation in human skin xenografts.
Laboratory investigation; a journal of technical methods and pathology 2000;80(4):595-604.
2000: Kapaettu Satyamoorthy; M Oka; Meenhard Herlyn
An antisense strategy for inhibition of human melanoma growth targets the growth factor pleiotrophin.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2000;13 Suppl 8():87-93.
2000: KG Sylvester; M Nesbit; Antoneta Radu; Meenhard Herlyn; N Scott Adzick; Timothy M Crombleholme
Adenoviral-mediated gene transfer in wound healing: acute inflammatory response in human skin in the SCID mouse model.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2000;8(1):36-44.
2000: Friedegund Meier; Mark Nesbit; Mei-Yu Hsu; B Martin; Patricia Van Belle; David E Elder; G Schaumburg-Lever; C Garbe; T M Walz; P Donatien; Timothy M Crombleholme; Meenhard Herlyn
Human melanoma progression in skin reconstructs : biological significance of bFGF.
The American journal of pathology 2000;156(1):193-200.
1999: Mark Nesbit; H K Nesbit; J Bennett; T Andl; Mei-Yu Hsu; E Dejesus; M McBrian; A R Gupta; Stephen L Eck; Meenhard Herlyn
Basic fibroblast growth factor induces a transformed phenotype in normal human melanocytes.
Oncogene 1999;18(47):6469-76.
1999: JY Hsu; Mei-Yu Hsu; T Sorger; Meenhard Herlyn; E M Levine
Heparin/endothelial cell growth supplement regulates matrix gene expression and prolongs life span of vascular smooth muscle cells through modulation of interleukin-1.
In vitro cellular & developmental biology. Animal 1999;35(10):647-54.
1999: David J Easty; Simon P Hill; M Y Hsu; M E Fallowfield; V A Florenes; Meenhard Herlyn; Dorothy C Bennett
Up-regulation of ephrin-A1 during melanoma progression.
International journal of cancer. Journal international du cancer 1999;84(5):494-501.
1999: Edward R Sauter; M Nesbit; Samuel Litwin; Andres J P Klein-Szanto; S Cheffetz; Meenhard Herlyn
Antisense cyclin D1 induces apoptosis and tumor shrinkage in human squamous carcinomas.
Cancer research 1999;59(19):4876-81.
1999: Kenneth W Liechty; M Nesbit; Meenhard Herlyn; Antoneta Radu; N Scott Adzick; Timothy M Crombleholme
Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing.
The Journal of investigative dermatology 1999;113(3):375-83.
1999: Ninad Prabhu; K Somasundaram; H Tian; Greg H Enders; K Satyamoorthy; Meenhard Herlyn; Wafik S El-Deiry
The administration schedule of cyclin-dependent kinase inhibitor gene therapy and etoposide chemotherapy is a major determinant of cytotoxicity.
International journal of oncology 1999;15(2):209-16.
1999: Patricia Van Belle; Rosalie Elenitsas; Kapaettu Satyamoorthy; J T Wolfe; DuPont Guerry; L Schuchter; T J Van Belle; S Albelda; P Tahin; Meenhard Herlyn; David E Elder
Progression-related expression of beta3 integrin in melanomas and nevi.
Human pathology 1999;30(5):562-7.
1999: Jayashree Mitra; Charlotte Y Dai; K Somasundaram; Wafik S El-Deiry; K Satyamoorthy; Meenhard Herlyn; Greg H Enders
Induction of p21(WAF1/CIP1) and inhibition of Cdk2 mediated by the tumor suppressor p16(INK4a).
Molecular and cellular biology 1999;19(5):3916-28.
1999: Edward R Sauter; M Nesbit; J C Watson; Andres Klein-Szanto; Samuel Litwin; Meenhard Herlyn
Vascular endothelial growth factor is a marker of tumor invasion and metastasis in squamous cell carcinomas of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):775-82.
1999: Kapaettu Satyamoorthy; Friedegund Meier; Mei-Yu Hsu; Carola Berking; Meenhard Herlyn
Human xenografts, human skin and skin reconstructs for studies in melanoma development and progression.
Cancer metastasis reviews 1999;18(3):401-5.
1998: Edward R Sauter; Andres J P Klein-Szanto; ES Atillasoy; Kathleen T Montone; Tamra Goodrow; Robert L Binder; John T Seykora; Meenhard Herlyn
Ultraviolet B-induced squamous epithelial and melanocytic cell changes in a xenograft model of cancer development in human skin.
Molecular carcinogenesis 1998;23(3):168-74.
1998: Edward R Sauter; Meenhard Herlyn
Molecular biology of human melanoma development and progression.
Molecular carcinogenesis 1998;23(3):132-43.
1998: Mei-Yu Hsu; D T Shih; Friedegund Meier; Patricia Van Belle; JY Hsu; David E Elder; C A Buck; Meenhard Herlyn
Adenoviral gene transfer of beta3 integrin subunit induces conversion from radial to vertical growth phase in primary human melanoma.
The American journal of pathology 1998;153(5):1435-42.
1998: Friedegund Meier; Kapaettu Satyamoorthy; Mark Nesbit; Mei-Yu Hsu; Birgit Schittek; C Garbe; Meenhard Herlyn
Molecular events in melanoma development and progression.
Frontiers in bioscience : a journal and virtual library 1998;3():D1005-10.
1998: Gerd G Maul; DE Jensen; Alexander M Ishov; Meenhard Herlyn; Frank J Rauscher
Nuclear redistribution of BRCA1 during viral infection.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(9):743-55.
1998: Ninad Prabhu; K Somasundaram; K Satyamoorthy; Meenhard Herlyn; Wafik S El-Deiry
p73beta, unlike p53, suppresses growth and induces apoptosis of human papillomavirus E6-expressing cancer cells.
International journal of oncology 1998;13(1):5-9.
1998: ES Atillasoy; John T Seykora; P W Soballe; Rosalie Elenitsas; Mark Nesbit; David E Elder; Kathleen T Montone; Edward R Sauter; Meenhard Herlyn
UVB induces atypical melanocytic lesions and melanoma in human skin.
The American journal of pathology 1998;152(5):1179-86.
1998: Frank J Rauscher; J F Morris; William Fredericks; JM Lopez-Guisa; C Balakrishnan; M Jost; Meenhard Herlyn; Ulrich Rodeck
Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein.
Hybridoma 1998;17(2):191-8.
1998: DL Cass; KM Bullard; KG Sylvester; EY Yang; D Sheppard; Meenhard Herlyn; N Scott Adzick
Epidermal integrin expression is upregulated rapidly in human fetal wound repair.
Journal of pediatric surgery 1998;33(2):312-6.
1997: ES Atillasoy; Rosalie Elenitsas; Edward R Sauter; P W Soballe; Meenhard Herlyn
UVB induction of epithelial tumors in human skin using a RAG-1 mouse xenograft model.
The Journal of investigative dermatology 1997;109(6):704-9.
1997: Ie-Ming Shih; David W Speicher; Mei-Yu Hsu; E Levine; Meenhard Herlyn
Melanoma cell-cell interactions are mediated through heterophilic Mel-CAM/ligand adhesion.
Cancer research 1997;57(17):3835-40.
1997: L M Shih; Mei-Yu Hsu; J P Palazzo; Meenhard Herlyn
The cell-cell adhesion receptor Mel-CAM acts as a tumor suppressor in breast carcinoma.
The American journal of pathology 1997;151(3):745-51.
1997: Kapaettu Satyamoorthy; E DeJesus; Alban Linnenbach; Barbara J Kraj; D L Kornreich; S Rendle; David E Elder; Meenhard Herlyn
Melanoma cell lines from different stages of progression and their biological and molecular analyses.
Melanoma research 1997;7 Suppl 2():S35-42.
1997: RJ Wechsler-Reya; K Elliott; Meenhard Herlyn; George C Prendergast
The putative tumor suppressor BIN1 is a short-lived nuclear phosphoprotein, the localization of which is altered in malignant cells.
Cancer research 1997;57(15):3258-63.
1997: Kapaettu Satyamoorthy; P W Soballe; F Soans; Meenhard Herlyn
Adenovirus infection enhances killing of melanoma cells by a mitotoxin.
Cancer research 1997;57(10):1873-6.
1996: Meenhard Herlyn; Kapaettu Satyamoorthy
Activated ras. Yet another player in melanoma?
The American journal of pathology 1996;149(3):739-44.
1996: Mei-Yu Hsu; M J Wheelock; K R Johnson; Meenhard Herlyn
Shifts in cadherin profiles between human normal melanocytes and melanomas.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1996;1(2):188-94.
1996: P W Soballe; Kathleen T Montone; Kapaettu Satyamoorthy; Mark Nesbit; Meenhard Herlyn
Carcinogenesis in human skin grafted to SCID mice.
Cancer research 1996;56(4):757-64.
1995: P W Soballe; W L Maloy; M L Myrga; L S Jacob; Meenhard Herlyn
Experimental local therapy of human melanoma with lytic magainin peptides.
International journal of cancer. Journal international du cancer 1995;60(2):280-4.
1994: Ie-Ming Shih; David E Elder; Mei-Yu Hsu; Meenhard Herlyn
Regulation of Mel-CAM/MUC18 expression on melanocytes of different stages of tumor progression by normal keratinocytes.
The American journal of pathology 1994;145(4):837-45.
1994: P W Soballe; Meenhard Herlyn
Cellular pathways leading to melanoma differentiation: therapeutic implications.
Melanoma research 1994;4(4):213-23.
1994: N Hijiya; J Zhang; Mariusz Z Ratajczak; J A Kant; K DeRiel; Meenhard Herlyn; G Zon; Alan M Gewirtz
Biologic and therapeutic significance of MYB expression in human melanoma.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4499-503.
1994: Ie-Ming Shih; David E Elder; D Speicher; J P Johnson; Meenhard Herlyn
Isolation and functional characterization of the A32 melanoma-associated antigen.
Cancer research 1994;54(9):2514-20.
1994: Meenhard Herlyn; Ie-Ming Shih
Interactions of melanocytes and melanoma cells with the microenvironment.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1994;7(2):81-8.
1994: Ie-Ming Shih; Meenhard Herlyn
Autocrine and paracrine roles for growth factors in melanoma.
In vivo (Athens, Greece) 1994;8(1):113-23.
1993: I Juhasz; GERALD LAZARUS; George F Murphy; Ie-Ming Shih; Meenhard Herlyn
Development of pemphigus vulgaris-like lesions in severe combined immunodeficiency disease mice reconstituted with lymphocytes from patients.
The Journal of clinical investigation 1993;92(5):2401-7.
1993: I Juhasz; George F Murphy; H C Yan; Meenhard Herlyn; Steven M Albelda
Regulation of extracellular matrix proteins and integrin cell substratum adhesion receptors on epithelium during cutaneous human wound healing in vivo.
The American journal of pathology 1993;143(5):1458-69.
1993: I T Valyi-Nagy; G Hirka; P J Jensen; Ie-Ming Shih; I Juhasz; Meenhard Herlyn
Undifferentiated keratinocytes control growth, morphology, and antigen expression of normal melanocytes through cell-cell contact.
Laboratory investigation; a journal of technical methods and pathology 1993;69(2):152-9.
1993: I Juhasz; Steven M Albelda; David E Elder; George F Murphy; K Adachi; D Herlyn; I T Valyi-Nagy; Meenhard Herlyn
Growth and invasion of human melanomas in human skin grafted to immunodeficient mice.
The American journal of pathology 1993;143(2):528-37.
1993: I Valyi-Nagy; Ie-Ming Shih; T Györfi; D Greenstein; I Juhasz; David E Elder; Meenhard Herlyn
Spontaneous and induced differentiation of human melanoma cells.
International journal of cancer. Journal international du cancer 1993;54(1):159-65.
1993: A Menrad; D Speicher; J Wacker; Meenhard Herlyn
Biochemical and functional characterization of aminopeptidase N expressed by human melanoma cells.
Cancer research 1993;53(6):1450-5.
1993: B Lazzaro; David E Elder; A Rebers; L Power; Meenhard Herlyn; A Menrad; B Johnson
Immunophenotyping of compound and spitz nevi and vertical growth-phase melanomas using a panel of monoclonal antibodies reactive in paraffin sections.
The Journal of investigative dermatology 1993;100(3):313S-317S.
1993: M L Mancianti; T Györfi; Ie-Ming Shih; I Valyi-Nagy; G Levengood; Hans D Menssen; Allan C Halpern; David E Elder; Meenhard Herlyn
Growth regulation of cultured human nevus cells.
The Journal of investigative dermatology 1993;100(3):281S-287S.
1993: H C Yan; I Juhasz; J Pilewski; George F Murphy; Meenhard Herlyn; Steven M Albelda
Human/severe combined immunodeficient mouse chimeras. An experimental in vivo model system to study the regulation of human endothelial cell-leukocyte adhesion molecules.
The Journal of clinical investigation 1993;91(3):986-96.
1993: Ie-Ming Shih; Meenhard Herlyn
Role of growth factors and their receptors in the development and progression of melanoma.
The Journal of investigative dermatology 1993;100(2 Suppl):196S-203S.
1993: D Iliopoulos; B Atkinson; S H Saul; Meenhard Herlyn; H A Rodriguez-Martinez; Suzanne L West; Greg Maislin; R D Soloway; Brian L Strom
Differences in antigen expression between neoplastic and nonneoplastic gallbladder epithelium. An immunohistochemical study.
Digestive diseases and sciences 1993;38(1):155-60.
1992: Ullrich Graeven; Ulrich Rodeck; roberto weinmann; Meenhard Herlyn
Stable transfection of human malignant melanoma cells with basic fibroblast growth factor antisense cDNA.
Annals of the New York Academy of Sciences 1992;660():293-4.
1992: Ullrich Graeven; Meenhard Herlyn
In vitro growth patterns of normal human melanocytes and melanocytes from different stages of melanoma progression.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1992;12(3):199-202.
1992: A Menrad; Meenhard Herlyn
Tumor progression, biology, and host response in melanoma.
Current opinion in oncology 1992;4(2):351-6.
1992: N N Williams; T Györfi; D Iliopoulos; Dorothee Herlyn; D Greenstein; A J Linnenbach; J M Daly; P Jensen; Ulrich Rodeck; Meenhard Herlyn
Growth-factor-independence and invasive properties of colorectal carcinoma cells.
International journal of cancer. Journal international du cancer 1992;50(2):274-80.
1992: David E Elder; Meenhard Herlyn
Antigens associated with tumor progression in melanocytic neoplasia.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;Suppl 2():136-43.
1991: Meenhard Herlyn; Ullrich Graeven; D Speicher; B A Sela; Jeannette L Bennicelli; R Kath; DuPont Guerry
Characterization of tenascin secreted by human melanoma cells.
Cancer research 1991;51(18):4853-8.
1991: Meenhard Herlyn; S B Malkowicz
Regulatory pathways in tumor growth and invasion.
Laboratory investigation; a journal of technical methods and pathology 1991;65(3):262-71.
1991: Ulrich Rodeck; K Melber; R Kath; Hans D Menssen; M Varello; B Atkinson; Meenhard Herlyn
Constitutive expression of multiple growth factor genes by melanoma cells but not normal melanocytes.
The Journal of investigative dermatology 1991;97(1):20-6.
1991: Ulrich Rodeck; Meenhard Herlyn
Growth factors in melanoma.
Cancer metastasis reviews 1991;10(2):89-101.
1991: R Kath; J A Jambrosic; L Holland; Ulrich Rodeck; Meenhard Herlyn
Development of invasive and growth factor-independent cell variants from primary human melanomas.
Cancer research 1991;51(8):2205-11.
1991: I Valyi-Nagy; Ulrich Rodeck; R Kath; M L Mancianti; W H Clark; Meenhard Herlyn
The human melanocyte system as a model for studies on tumor progression.
Basic life sciences 1991;57():315-26; discussion 326-8.
1990: Meenhard Herlyn; A Menrad; Hilary Koprowski
Structure, function, and clinical significance of human tumor antigens.
Journal of the National Cancer Institute 1990;82(24):1883-9.
1990: Steven M Albelda; S A Mette; David E Elder; R Stewart; L Damjanovich; Meenhard Herlyn; CA Buck
Integrin distribution in malignant melanoma: association of the beta 3 subunit with tumor progression.
Cancer research 1990;50(20):6757-64.
1990: Ulrich Rodeck; N Williams; U Murthy; Meenhard Herlyn
Monoclonal antibody 425 inhibits growth stimulation of carcinoma cells by exogenous EGF and tumor-derived EGF/TGF-alpha.
Journal of cellular biochemistry 1990;44(2):69-79.
1990: Meenhard Herlyn
Human melanoma: development and progression.
Cancer metastasis reviews 1990;9(2):101-12.
1990: CC Howe; R Kath; M L Mancianti; Meenhard Herlyn; S Mueller; Vincent J Cristofalo
Expression and structure of human SPARC transcripts: SPARC mRNA is expressed by human cells involved in extracellular matrix production and some of these cells show an unusual expression pattern.
Experimental cell research 1990;188(2):185-91.
1990: Brian L Strom; Greg Maislin; Suzanne L West; B Atkinson; Meenhard Herlyn; S Saul; H A Rodriguez-Martinez; J Rios-Dalenz; D Iliopoulos; R D Soloway
Serum CEA and CA 19-9: potential future diagnostic or screening tests for gallbladder cancer?
International journal of cancer. Journal international du cancer 1990;45(5):821-4.
1990: M L Mancianti; W H Clark; F A Hayes; Meenhard Herlyn
Malignant melanoma simulants arising in congenital melanocytic nevi do not show experimental evidence for a malignant phenotype.
The American journal of pathology 1990;136(4):817-29.
1990: I T Valyi-Nagy; George F Murphy; M L Mancianti; D Whitaker; Meenhard Herlyn
Phenotypes and interactions of human melanocytes and keratinocytes in an epidermal reconstruction model.
Laboratory investigation; a journal of technical methods and pathology 1990;62(3):314-24.
1990: Meenhard Herlyn; R Kath; N Williams; I Valyi-Nagy; Ulrich Rodeck
Growth-regulatory factors for normal, premalignant, and malignant human cells in vitro.
Advances in cancer research 1990;54():213-34.
1989: J Jambrosic; M L Mancianti; Robert P Ricciardi; B A Sela; Hilary Koprowski; Meenhard Herlyn
Transformation of normal human melanocytes and non-malignant nevus cells by adenovirus 12-SV40 hybrid virus.
International journal of cancer. Journal international du cancer 1989;44(6):1117-23.
1989: Brian L Strom; D Iliopoulos; B Atkinson; Meenhard Herlyn; Suzanne L West; Greg Maislin; S Saul; M A Varello; H A Rodriguez-Martinez; J Rios-Dalenz
Pathophysiology of tumor progression in human gallbladder: flow cytometry, CEA, and CA 19-9 levels in bile and serum in different stages of gallbladder disease.
Journal of the National Cancer Institute 1989;81(20):1575-80.
1989: David E Elder; Ulrich Rodeck; J Thurin; F Cardillo; W H Clark; R Stewart; Meenhard Herlyn
Antigenic profile of tumor progression stages in human melanocytic nevi and melanomas.
Cancer research 1989;49(18):5091-6.
1989: R Kath; Ulrich Rodeck; Hans D Menssen; M L Mancianti; A J Linnenbach; David E Elder; Meenhard Herlyn
Tumor progression in the human melanocytic system.
Anticancer research 1989;9(4):865-72.
1989: R Kath; Meenhard Herlyn
Molecular biology of tumor antigens.
Current opinion in immunology 1989;1(5):863-6.
1989: D Iliopoulos; C Ernst; Z Steplewski; J A Jambrosic; Ulrich Rodeck; Meenhard Herlyn; W H Clark; Hilary Koprowski; Dorothee Herlyn
Inhibition of metastases of a human melanoma xenograft by monoclonal antibody to the GD2/GD3 gangliosides.
Journal of the National Cancer Institute 1989;81(6):440-4.
1989: M L Mancianti; Meenhard Herlyn
Tumor progression in melanoma: the biology of epidermal melanocytes in vitro.
Carcinogenesis; a comprehensive survey 1989;11():369-86.
1988: E M Rakowicz-Szulczyńska; Meenhard Herlyn; Hilary Koprowski
Nerve growth factor receptors in chromatin of melanoma cells, proliferating melanocytes, and colorectal carcinoma cells in vitro.
Cancer research 1988;48(24 Pt 1):7200-6.
1988: Meenhard Herlyn; M L Mancianti; J Jambrosic; J B Bolen; Hilary Koprowski
Regulatory factors that determine growth and phenotype of normal human melanocytes.
Experimental cell research 1988;179(2):322-31.
1988: M L Mancianti; Meenhard Herlyn; D Weil; J Jambrosic; Ulrich Rodeck; D Becker; L Diamond; W H Clark; Hilary Koprowski
Growth and phenotypic characteristics of human nevus cells in culture.
The Journal of investigative dermatology 1988;90(2):134-41.
1988: A J Linnenbach; Kay Huebner; E Premkumar Reddy; Meenhard Herlyn; A H Parmiter; Peter C Nowell; Hilary Koprowski
Structural alteration in the MYB protooncogene and deletion within the gene encoding alpha-type protein kinase C in human melanoma cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):74-8.
1987: Ulrich Rodeck; Meenhard Herlyn; Hilary Koprowski
Interactions between growth factor receptors and corresponding monoclonal antibodies in human tumors.
Journal of cellular biochemistry 1987;35(4):315-20.
1987: Hans D Menssen; Meenhard Herlyn; Ulrich Rodeck; Hilary Koprowski
Rapid dissociation of adherent human tumor cells by ultrasound.
Journal of immunological methods 1987;104(1-2):1-6.
1987: Ulrich Rodeck; Meenhard Herlyn; Hans D Menssen; R W Furlanetto; H Koprowsk
Metastatic but not primary melanoma cell lines grow in vitro independently of exogenous growth factors.
International journal of cancer. Journal international du cancer 1987;40(5):687-90.
1987: Ulrich Rodeck; Meenhard Herlyn; D Herlyn; C Molthoff; B Atkinson; M Varello; Z Steplewski; H Koprowski
Tumor growth modulation by a monoclonal antibody to the epidermal growth factor receptor: immunologically mediated and effector cell-independent effects.
Cancer research 1987;47(14):3692-6.
1987: Meenhard Herlyn; Ulrich Rodeck; M Mancianti; F M Cardillo; A Lang; A H Ross; J Jambrosic; Hilary Koprowski
Expression of melanoma-associated antigens in rapidly dividing human melanocytes in culture.
Cancer research 1987;47(12):3057-61.
1987: A Basu; U Murthy; Ulrich Rodeck; Meenhard Herlyn; L Mattes; M Das
Presence of tumor-associated antigens in epidermal growth factor receptors from different human carcinomas.
Cancer research 1987;47(10):2531-6.
1987: Meenhard Herlyn; W H Clark; Ulrich Rodeck; M L Mancianti; J Jambrosic; Hilary Koprowski
Biology of tumor progression in human melanocytes.
Laboratory investigation; a journal of technical methods and pathology 1987;56(5):461-74.
1987: Meenhard Herlyn; Ulrich Rodeck; Hilary Koprowski
Shedding of human tumor-associated antigens in vitro and in vivo.
Advances in cancer research 1987;49():189-221.
1986: C S Ernst; J W Shen; S Litwin; Meenhard Herlyn; H Koprowski; H F Sears
Multiparameter evaluation of the expression in situ of normal and tumor-associated antigens in human colorectal carcinoma.
Journal of the National Cancer Institute 1986;77(2):387-95.
1986: C S Ernst; H F Sears; Meenhard Herlyn; Dorothee Herlyn; Z Steplewski; Hilary Koprowski
Detection of murine immunoglobulin in human tissues following therapeutic infusion of monoclonal antibody.
Hybridoma 1986;5 Suppl 1():S79-86.
1986: E M Rakowicz-Szulczynska; Ulrich Rodeck; Meenhard Herlyn; Hilary Koprowski
Chromatin binding of epidermal growth factor, nerve growth factor, and platelet-derived growth factor in cells bearing the appropriate surface receptors.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):3728-32.
1986: A H Parmiter; G Balaban; Meenhard Herlyn; W H Clark; Peter C Nowell
A t(1;19) chromosome translocation in three cases of human malignant melanoma.
Cancer research 1986;46(3):1526-9.
1986: C S Ernst; B Atkinson; D Chianese; J Peters; M Perry; Meenhard Herlyn; H Koprowski
Differential diagnosis between mesotheliomas and metastatic adenocarcinomas using monoclonal antibodies against gastrointestinal carcinoma antigen and stage-specific embryonic antigen.
Applied pathology 1986;4(3):115-24.
1985: Meenhard Herlyn; J Thurin; G Balaban; Jeannette L Bennicelli; D Herlyn; David E Elder; E Bondi; DuPont Guerry; Peter C Nowell; Wallace H Clark
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer research 1985;45(11 Pt 2):5670-6.
1985: H Koprowski; Meenhard Herlyn; G Balaban; A Parmiter; A Ross; Peter C Nowell
Expression of the receptor for epidermal growth factor correlates with increased dosage of chromosome 7 in malignant melanoma.
Somatic cell and molecular genetics 1985;11(3):297-302.
1985: H F Sears; J W Shen; Meenhard Herlyn; B Atkinson; P F Engstrom; H Koprowski
Circulating tumor markers and assessment of response to intrahepatic chemotherapy of colon carcinoma.
American journal of clinical oncology 1985;8(2):108-17.
1985: Meenhard Herlyn; G Balaban; Jeannette L Bennicelli; DuPont Guerry; R Halaban; D Herlyn; David E Elder; G G Maul; Z Steplewski; Peter C Nowell
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
Journal of the National Cancer Institute 1985;74(2):283-9.
1985: R Folberg; L A Donoso; B F Atkinson; C S Ernst; Meenhard Herlyn; V V Arbizo
An antimelanoma monoclonal antibody and the histopathology of uveal melanomas.
Archives of ophthalmology 1985;103(2):275-9.
1985: B Atkinson; C S Ernst; B F Ghrist; A H Ross; W H Clark; Meenhard Herlyn; Dorothee Herlyn; G Maul; Z Steplewski; H Koprowski
Monoclonal antibody to a highly glycosylated protein reacts in fixed tissue with melanoma and other tumors.
Hybridoma 1985;4(3):243-55.
1984: Meenhard Herlyn; H F Sears; H Verrill; H Koprowski
Increased sensitivity in detecting tumor-associated antigens in sera of patients with colorectal carcinoma.
Journal of immunological methods 1984;75(1):15-21.
1984: A H Ross; P Grob; Mark Bothwell; David E Elder; C S Ernst; N Marano; B F Ghrist; C C Slemp; Meenhard Herlyn; B Atkinson
Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(21):6681-5.
1984: A H Ross; Meenhard Herlyn; C S Ernst; DuPont Guerry; Jeannette L Bennicelli; B F Ghrist; B Atkinson; H Koprowski
Immunoassay for melanoma-associated proteoglycan in the sera of patients using monoclonal and polyclonal antibodies.
Cancer research 1984;44(10):4642-7.
1984: B Atkinson; C S Ernst; B F Ghrist; Meenhard Herlyn; M Blaszczyk; A H Ross; Dorothee Herlyn; Z Steplewski; H Koprowski
Identification of melanoma-associated antigens using fixed tissue screening of antibodies.
Cancer research 1984;44(6):2577-81.
1984: G Balaban; Meenhard Herlyn; DuPont Guerry; R Bartolo; H Koprowski; Wallace H Clark; Peter C Nowell
Cytogenetics of human malignant melanoma and premalignant lesions.
Cancer genetics and cytogenetics 1984;11(4):429-39.
1984: Meenhard Herlyn; B Lange; Jeannette L Bennicelli; M Blaszczyk; DuPont Guerry; H Koprowski
Increased levels of circulating HLA-DR antigen in sera of patients with acute lymphoblastoid leukemia.
Leukemia research 1984;8(3):323-34.
1984: Meenhard Herlyn; J W Shen; H F Sears; Curt I Civin; H L Verrill; E M Goldberg; H Koprowski
Detection of a circulating gastrointestinal cancer antigen in sera of patients with gastrointestinal malignancies by a double determinant immunoassay with monoclonal antibodies against human blood group determinants.
Clinical and experimental immunology 1984;55(1):23-35.
1983: Meenhard Herlyn; D Herlyn; David E Elder; E Bondi; D LaRossa; R Hamilton; H F Sears; G Balaban; DuPont Guerry; Wallace H Clark
Phenotypic characteristics of cells derived from precursors of human melanoma.
Cancer research 1983;43(11):5502-8.
1983: Meenhard Herlyn; M Blaszczyk; H F Sears; H Verrill; J Lindgren; D Colcher; Z Steplewski; J Schlom; H Koprowski
Detection of carcinoembryonic antigen and related antigens in sera of patients with gastrointestinal tumors using monoclonal antibodies in double-determinant radioimmunoassays.
Hybridoma 1983;2(3):329-39.
1982: B F Atkinson; C S Ernst; Meenhard Herlyn; Z Steplewski; H F Sears; H Koprowski
Gastrointestinal cancer-associated antigen in immunoperoxidase assay.
Cancer research 1982;42(11):4820-3.
1982: Meenhard Herlyn; Z Steplewski; B F Atkinson; C S Ernst; H Koprowski
Comparative study of the binding characteristics of monoclonal antimelanoma antibodies.
Hybridoma 1982;1(4):403-11.
1980: Meenhard Herlyn; Wallace H Clark; M J Mastrangelo; DuPont Guerry; David E Elder; D LaRossa; R Hamilton; E Bondi; R Tuthill; Z Steplewski; H Koprowski
Specific immunoreactivity of hybridoma-secreted monoclonal anti-melanoma antibodies to cultured cells and freshly derived human cells.
Cancer research 1980;40(10):3602-9.