Username

Password

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

James Herman

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Tumor Suppressor Genes

Procedures

Polymerase Chain Reaction

Anatomy

Disorders

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Ye Ying; McDevitt Michael A; Guo Mingzhou; Zhang Wei; Galm Oliver; Gore Steven D; Karp Judith E; Maciejewski Jaroslaw P; Kowalski Jeanne; Tsai Hua-Ling; Gondek Lukasz P; Tsai Hsing-Chen; Wang Xiaofei; Hooker Craig; Smith B Douglas; Carraway Hetty E; Herman James G
Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.
Lin Jianqing; Gilbert Jill; Rudek Michelle A; Zwiebel James A; Gore Steve; Jiemjit Anchalee; Zhao Ming; Baker Sharyn D; Ambinder Richard F; Herman James G; Donehower Ross C; Carducci Michael A
A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.
Rudin Charles M; Avila-Tang Erika; Harris Curtis C; Herman James G; Hirsch Fred R; Pao William; Schwartz Ann G; Vahakangas Kirsi H; Samet Jonathan M
Lung cancer in never smokers: molecular profiles and therapeutic implications.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of James Herman (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Ye Ying; McDevitt Michael A; Guo Mingzhou; Zhang Wei; Galm Oliver; Gore Steven D; Karp Judith E; Maciejewski Jaroslaw P; Kowalski Jeanne; Tsai Hua-Ling; Gondek Lukasz P; Tsai Hsing-Chen; Wang Xiaofei; Hooker Craig; Smith B Douglas; Carraway Hetty E; Herman James G
Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.
Cancer research 2009;69(21):8482-90.
2009: Lin Jianqing; Gilbert Jill; Rudek Michelle A; Zwiebel James A; Gore Steve; Jiemjit Anchalee; Zhao Ming; Baker Sharyn D; Ambinder Richard F; Herman James G; Donehower Ross C; Carducci Michael A
A phase I dose-finding study of 5-azacytidine in combination with sodium phenylbutyrate in patients with refractory solid tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6241-9.
2009: Rudin Charles M; Avila-Tang Erika; Harris Curtis C; Herman James G; Hirsch Fred R; Pao William; Schwartz Ann G; Vahakangas Kirsi H; Samet Jonathan M
Lung cancer in never smokers: molecular profiles and therapeutic implications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(18):5646-61.
2009: Wang Jean S; Guo Mingzhou; Montgomery Elizabeth A; Thompson Richard E; Cosby Hilary; Hicks Lisa; Wang Shelun; Herman James G; Canto Marcia I
DNA promoter hypermethylation of p16 and APC predicts neoplastic progression in Barrett's esophagus.
The American journal of gastroenterology 2009;104(9):2153-60.
2009: Fandy Tamer E; Herman James G; Kerns Patrick; Jiemjit Anchalee; Sugar Elizabeth A; Choi Si-Ho; Yang Allen S; Aucott Timothy; Dauses Tianna; Odchimar-Reissig Rosalie; Licht Jonathan; McConnell Melanie J; Nasrallah Chris; Kim Marianne K H; Zhang Weijia; Sun Yezou; Murgo Anthony; Espinoza-Delgado Igor; Oteiza Katharine; Owoeye Ibitayo; Silverman Lewis R; Gore Steven D; Carraway Hetty E
Early epigenetic changes and DNA damage do not predict clinical response in an overlapping schedule of 5-azacytidine and entinostat in patients with myeloid malignancies.
Blood 2009;114(13):2764-73.
2009: Bailey Vasudev J; Easwaran Hariharan; Zhang Yi; Griffiths Elizabeth; Belinsky Steven A; Herman James G; Baylin Stephen B; Carraway Hetty E; Wang Tza-Huei
MS-qFRET: a quantum dot-based method for analysis of DNA methylation.
Genome research 2009;19(8):1455-61.
2009: Jost E; Gezer D; Wilop S; Suzuki H; Herman J G; Osieka R; Galm O
Epigenetic dysregulation of secreted Frizzled-related proteins in multiple myeloma.
Cancer letters 2009;281(1):24-31.
2009: Melotte Veerle; Lentjes Marjolein H F M; van den Bosch Sandra M; Hellebrekers Debby M E I; de Hoon Joep P J; Wouters Kim A D; Daenen Kathleen L J; Partouns-Hendriks Iris E J M; Stessels Filip; Louwagie Joost; Smits Kim M; Weijenberg Matty P; Sanduleanu Silvia; Khalid-de Bakker Carolina A J; Oort Frank A; Meijer Gerrit A; Jonkers Daisy M A E; Herman James G; de Bruïne Adriaan P; van Engeland Manon
N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer.
Journal of the National Cancer Institute 2009;101(13):916-27.
2009: de Vogel S; Weijenberg M P; Herman J G; Wouters K A D; de Goeij A F P M; van den Brandt P A; de Bruïne A P; van Engeland M
MGMT and MLH1 promoter methylation versus APC, KRAS and BRAF gene mutations in colorectal cancer: indications for distinct pathways and sequence of events.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2009;20(7):1216-22.
2009: Hellebrekers Debby M E I; Lentjes Marjolein H F M; van den Bosch Sandra M; Melotte Veerle; Wouters Kim A D; Daenen Kathleen L J; Smits Kim M; Akiyama Yoshimitsu; Yuasa Yasuhito; Sanduleanu Silvia; Khalid-de Bakker Carolina A J; Jonkers Daisy; Weijenberg Matty P; Louwagie Joost; van Criekinge Wim; Carvalho Beatriz; Meijer Gerrit A; Baylin Stephen B; Herman James G; de Bruïne Adriaan P; van Engeland Manon
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):3990-7.
2009: Glöckner Sabine C; Dhir Mashaal; Yi Joo Mi; McGarvey Kelly E; Van Neste Leander; Louwagie Joost; Chan Timothy A; Kleeberger Wolfram; de Bruïne Adriaan P; Smits Kim M; Khalid-de Bakker Carolina A J; Jonkers Daisy M A E; Stockbrügger Reinhold W; Meijer Gerrit A; Oort Frank A; Iacobuzio-Donahue Christine; Bierau Katja; Herman James G; Baylin Stephen B; Van Engeland Manon; Schuebel Kornel E; Ahuja Nita
Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.
Cancer research 2009;69(11):4691-9.
2009: Cavallari Ilaria; Silic-Benussi Micol; Rende Francesca; Martines Annalisa; Fogar Paola; Basso Daniela; Vella Manuela Della; Pedrazzoli Sergio; Herman James G; Chieco-Bianchi Luigi; Esposito Giovanni; Ciminale Vincenzo; D'Agostino Donna M
Decreased expression and promoter methylation of the menin tumor suppressor in pancreatic ductal adenocarcinoma.
Genes, chromosomes & cancer 2009;48(5):383-96.
2009: Zhang Yi; Bailey Vasudev; Puleo Christopher M; Easwaran Hariharan; Griffiths Elizabeth; Herman James G; Baylin Stephen B; Wang Tza-Huei
DNA methylation analysis on a droplet-in-oil PCR array.
Lab on a chip 2009;9(8):1059-64.
2009: Vogelbaum Michael A; Berkey Brian; Peereboom David; Macdonald David; Giannini Caterina; Suh John H; Jenkins Robert; Herman James; Brown Paul; Blumenthal Deborah T; Biggs Christopher; Schultz Christopher; Mehta Minesh
Phase II trial of preirradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: RTOG BR0131.
Neuro-oncology 2009;11(2):167-75.
2009: Jost Edgar; do O Nicole; Wilop Stefan; Herman James G; Osieka Rainhardt; Galm Oliver
Aberrant DNA methylation of the transcription factor C/EBPalpha in acute myelogenous leukemia.
Leukemia research 2009;33(3):443-9.
2009: Carraway Hetty E; Wang Shelun; Blackford Amanda; Guo Mingzho; Powers Penny; Jeter Stacie; Davidson Nancy E; Argani Pedram; Terrell Kyle; Herman James G; Lange Julie R
Promoter hypermethylation in sentinel lymph nodes as a marker for breast cancer recurrence.
Breast cancer research and treatment 2009;114(2):315-25.
2009: Lam Tram Kim; Gallicchio Lisa; Lindsley Kristina; Shiels Meredith; Hammond Edward; Tao Xuguang Grant; Chen Liwei; Robinson Karen A; Caulfield Laura E; Herman James G; Guallar Eliseo; Alberg Anthony J
Cruciferous vegetable consumption and lung cancer risk: a systematic review.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(1):184-95.
2009: Chen Liwei; Gallicchio Lisa; Boyd-Lindsley Kristina; Tao Xuguang Grant; Robinson Karen A; Lam Tram Kim; Herman James G; Caulfield Laura E; Guallar Eliseo; Alberg Anthony J
Alcohol consumption and the risk of nasopharyngeal carcinoma: a systematic review.
Nutrition and cancer 2009;61(1):1-15.
2009: Licchesi Julien D F; Herman James G
Methylation-specific PCR.
Methods in molecular biology (Clifton, N.J.) 2009;507():305-23.
2008: Smits Kim M; Cleven Arjen H G; Weijenberg Matty P; Hughes Laura A E; Herman James G; de Bruïne Adriaan P; van Engeland Manon
Pharmacoepigenomics in colorectal cancer: a step forward in predicting prognosis and treatment response.
Pharmacogenomics 2008;9(12):1903-16.
2008: Tiwari Vijay K; McGarvey Kelly M; Licchesi Julien D F; Ohm Joyce E; Herman James G; Schübeler Dirk; Baylin Stephen B
PcG proteins, DNA methylation, and gene repression by chromatin looping.
PLoS biology 2008;6(12):2911-27.
2008: Misawa Kiyoshi; Ueda Yo; Kanazawa Takeharu; Misawa Yuki; Jang Ilwhan; Brenner John Chadwick; Ogawa Tetsuya; Takebayashi Satoru; Grenman Reidar A; Herman James G; Mineta Hiroyuki; Carey Thomas E
Epigenetic inactivation of galanin receptor 1 in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(23):7604-13.
2008: Alumkal Joshi J; Zhang Zhe; Humphreys Elizabeth B; Bennett Christina; Mangold Leslie A; Carducci Michael A; Partin Alan W; Garrett-Mayer Elizabeth; DeMarzo Angelo M; Herman James G
Effect of DNA methylation on identification of aggressive prostate cancer.
Urology 2008;72(6):1234-9.
2008: Guo Mingzhou; Ren Jingli; Brock Malcolm V; Herman James G; Carraway Hetty E
Promoter methylation of HIN-1 in the progression to esophageal squamous cancer.
Epigenetics : official journal of the DNA Methylation Society 2008;3(6):336-41.
2008: Hanigan Christin L; Van Engeland Manon; De Bruine Adriaan P; Wouters Kim A; Weijenberg Matty P; Eshleman James R; Herman James G
An inactivating mutation in HDAC2 leads to dysregulation of apoptosis mediated by APAF1.
Gastroenterology 2008;135(5):1654-1664.e2.
2008: Yi Joo Mi; Tsai Hsing-Chen; Glöckner Sabine C; Lin Steven; Ohm Joyce E; Easwaran Hari; James C David; Costello Joseph F; Riggins Gregory; Eberhart Charles G; Laterra John; Vescovi Angelo L; Ahuja Nita; Herman James G; Schuebel Kornel E; Baylin Stephen B
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Cancer research 2008;68(19):8094-103.
2008: Dhir Mashaal; Montgomery Elizabeth A; Glöckner Sabine C; Schuebel Kornel E; Hooker Craig M; Herman James G; Baylin Stephen B; Gearhart Susan L; Ahuja Nita
Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(10):1745-53.
2008: Hegi Monika E; Liu Lili; Herman James G; Stupp Roger; Wick Wolfgang; Weller Michael; Mehta Minesh P; Gilbert Mark R
Correlation of O6-methylguanine methyltransferase (MGMT) promoter methylation with clinical outcomes in glioblastoma and clinical strategies to modulate MGMT activity.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(25):4189-99.
2008: Jost E; Schmid J; Wilop S; Schubert C; Suzuki H; Herman J G; Osieka R; Galm O
Epigenetic inactivation of secreted Frizzled-related proteins in acute myeloid leukaemia.
British journal of haematology 2008;142(5):745-53.
2008: Celik Ismail; Gallicchio Lisa; Boyd Kristina; Lam Tram K; Matanoski Genevieve; Tao Xuguang; Shiels Meredith; Hammond Edward; Chen Liwei; Robinson Karen A; Caulfield Laura E; Herman James G; Guallar Eliseo; Alberg Anthony J
Arsenic in drinking water and lung cancer: a systematic review.
Environmental research 2008;108(1):48-55.
2008: Gallicchio Lisa; Boyd Kristina; Matanoski Genevieve; Tao Xuguang Grant; Chen Liwei; Lam Tram K; Shiels Meredith; Hammond Edward; Robinson Karen A; Caulfield Laura E; Herman James G; Guallar Eliseo; Alberg Anthony J
Carotenoids and the risk of developing lung cancer: a systematic review.
The American journal of clinical nutrition 2008;88(2):372-83.
2008: McGarvey Kelly M; Van Neste Leander; Cope Leslie; Ohm Joyce E; Herman James G; Van Criekinge Wim; Schuebel Kornel E; Baylin Stephen B
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.
Cancer research 2008;68(14):5753-9.
2008: Jiemjit A; Fandy T E; Carraway H; Bailey K A; Baylin S; Herman J G; Gore S D
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Oncogene 2008;27(25):3615-23.
2008: Chan Timothy A; Glockner Sabine; Yi Joo Mi; Chen Wei; Van Neste Leander; Cope Leslie; Herman James G; Velculescu Victor; Schuebel Kornel E; Ahuja Nita; Baylin Stephen B
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.
PLoS medicine 2008;5(5):e114.
2008: Licchesi Julien D F; Westra William H; Hooker Craig M; Herman James G
Promoter hypermethylation of hallmark cancer genes in atypical adenomatous hyperplasia of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(9):2570-8.
2008: Licchesi Julien D F; Westra William H; Hooker Craig M; Machida Emi O; Baylin Stephen B; Herman James G
Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.
Carcinogenesis 2008;29(5):895-904.
2008: Zhang Wei; Glöckner Sabine C; Guo Mingzhou; Machida Emi Ota; Wang David H; Easwaran Hariharan; Van Neste Leander; Herman James G; Schuebel Kornel E; Watkins D Neil; Ahuja Nita; Baylin Stephen B
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.
Cancer research 2008;68(8):2764-72.
2008: Brock Malcolm V; Hooker Craig M; Ota-Machida Emi; Han Yu; Guo Mingzhou; Ames Stephen; Glöckner Sabine; Piantadosi Steven; Gabrielson Edward; Pridham Genevieve; Pelosky Kristen; Belinsky Steven A; Yang Stephen C; Baylin Stephen B; Herman James G
DNA methylation markers and early recurrence in stage I lung cancer.
The New England journal of medicine 2008;358(11):1118-28.
2008: Derks Sarah; Postma Cindy; Carvalho Beatriz; van den Bosch Sandra M; Moerkerk Peter T M; Herman James G; Weijenberg Matty P; de Bruïne Adriaan P; Meijer Gerrit A; van Engeland Manon
Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations.
Carcinogenesis 2008;29(2):434-9.
2007: Yoshikawa Hirohide; Matsubara Kenichi; Zhou Xiaoling; Okamura Shu; Kubo Takahiko; Murase Yaeko; Shikauchi Yuko; Esteller Manel; Herman James G; Wei Wang Xin; Harris Curtis C
WNT10B functional dualism: beta-catenin/Tcf-dependent growth promotion or independent suppression with deregulated expression in cancer.
Molecular biology of the cell 2007;18(11):4292-303.
2007: Fu Baojin; Guo Mingzhou; Wang Shelun; Campagna Domenico; Luo Mingde; Herman James G; Iacobuzio-Donahue Christine A
Evaluation of GATA-4 and GATA-5 methylation profiles in human pancreatic cancers indicate promoter methylation patterns distinct from other human tumor types.
Cancer biology & therapy 2007;6(10):1546-52.
2007: Ryu Byungwoo; Kim Dave S; DeLuca Amena M; Healey Megan A; Dunlap Shariff; Fackler Mary Jo; Herman James; Alani Rhoda M
Id1 expression is transcriptionally regulated in radial growth phase melanomas.
International journal of cancer. Journal international du cancer 2007;121(8):1705-9.
2007: Schuebel Kornel E; Chen Wei; Cope Leslie; Glöckner Sabine C; Suzuki Hiromu; Yi Joo-Mi; Chan Timothy A; Van Neste Leander; Van Criekinge Wim; van den Bosch Sandra; van Engeland Manon; Ting Angela H; Jair Kamwing; Yu Wayne; Toyota Minoru; Imai Kohzoh; Ahuja Nita; Herman James G; Baylin Stephen B
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.
PLoS genetics 2007;3(9):1709-23.
2007: Guo MingZhou; House Michael G; Suzuki Hiromu; Ye Ying; Brock Malcolm V; Lu Fengmin; Liu Zhihua; Rustgi Anil K; Herman James G
Epigenetic silencing of CDX2 is a feature of squamous esophageal cancer.
International journal of cancer. Journal international du cancer 2007;121(6):1219-26.
2007: Brandes J C; Carraway H; Herman J G
Optimal primer design using the novel primer design program: MSPprimer provides accurate methylation analysis of the ATM promoter.
Oncogene 2007;26(42):6229-37.
2007: Hellebrekers Debby M E I; Melotte Veerle; Viré Emmanuelle; Langenkamp Elise; Molema Grietje; Fuks François; Herman James G; Van Criekinge Wim; Griffioen Arjan W; van Engeland Manon
Identification of epigenetically silenced genes in tumor endothelial cells.
Cancer research 2007;67(9):4138-48.
2007: Martinez Ramon; Schackert Gabriele; Yaya-Tur Ricard; Rojas-Marcos Iñigo; Herman James G; Esteller Manel
Frequent hypermethylation of the DNA repair gene MGMT in long-term survivors of glioblastoma multiforme.
Journal of neuro-oncology 2007;83(1):91-3.
2007: Heath Elisabeth I; Canto Marcia Irene; Piantadosi Steven; Montgomery Elizabeth; Weinstein Wilfred M; Herman James G; Dannenberg Andrew J; Yang Vincent W; Shar Albert O; Hawk Ernest; Forastiere Arlene A;
Secondary chemoprevention of Barrett's esophagus with celecoxib: results of a randomized trial.
Journal of the National Cancer Institute 2007;99(7):545-57.
2007: Jost E; do O N; Dahl E; Maintz C E; Jousten P; Habets L; Wilop S; Herman J G; Osieka R; Galm O
Epigenetic alterations complement mutation of JAK2 tyrosine kinase in patients with BCR/ABL-negative myeloproliferative disorders.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(3):505-10.
2007: Pijnenborg J M A; Dam-de Veen G C; Kisters N; Delvoux B; van Engeland M; Herman J G; Groothuis P G
RASSF1A methylation and K-ras and B-raf mutations and recurrent endometrial cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2007;18(3):491-7.
2007: Ohm Joyce E; McGarvey Kelly M; Yu Xiaobing; Cheng Linzhao; Schuebel Kornel E; Cope Leslie; Mohammad Helai P; Chen Wei; Daniel Vincent C; Yu Wayne; Berman David M; Jenuwein Thomas; Pruitt Kevin; Sharkis Saul J; Watkins D Neil; Herman James G; Baylin Stephen B
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nature genetics 2007;39(2):237-42.
2007: Brock Malcolm V; Herman James G; Baylin Stephen B
Cancer as a manifestation of aberrant chromatin structure.
Cancer journal (Sudbury, Mass.) 2007;13(1):3-8.
2007: Zinn Rebekah L; Pruitt Kevin; Eguchi Sayaka; Baylin Stephen B; Herman James G
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.
Cancer research 2007;67(1):194-201.
2007: Carraway Hetty; Herman James
Monitoring methylation and gene expression in cancer.
Methods in molecular biology (Clifton, N.J.) 2007;383():187-202.
2006: Chu Linda C; Eberhart Charles G; Grossman Stuart A; Herman James G
Epigenetic silencing of multiple genes in primary CNS lymphoma.
International journal of cancer. Journal international du cancer 2006;119(10):2487-91.
2006: Guo MingZhou; House Michael G; Akiyama Yoshimitsu; Qi Yu; Capagna Domenico; Harmon John; Baylin Stephen B; Brock Malcolm V; Herman James G
Hypermethylation of the GATA gene family in esophageal cancer.
International journal of cancer. Journal international du cancer 2006;119(9):2078-83.
2006: Singh Anju; Misra Vikas; Thimmulappa Rajesh K; Lee Hannah; Ames Stephen; Hoque Mohammad O; Herman James G; Baylin Stephen B; Sidransky David; Gabrielson Edward; Brock Malcolm V; Biswal Shyam
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
PLoS medicine 2006;3(10):e420.
2006: Benzeno S; Lu F; Guo M; Barbash O; Zhang F; Herman J G; Klein P S; Rustgi A; Diehl J A
Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1.
Oncogene 2006;25(47):6291-303.
2006: Brock Malcolm V; Hooker Craig M; Engels Eric A; Moore Richard D; Gillison Maura L; Alberg Anthony J; Keruly Jeanne C; Yang Stephen C; Heitmiller Richard F; Baylin Stephen B; Herman James G; Brahmer Julie R
Delayed diagnosis and elevated mortality in an urban population with HIV and lung cancer: implications for patient care.
Journal of acquired immune deficiency syndromes (1999) 2006;43(1):47-55.
2006: Gallicchio Lisa; Matanoski Genevieve; Tao Xuguang Grant; Chen Liwei; Lam Tram K; Boyd Kristina; Robinson Karen A; Balick Lyssa; Mickelson Stephanie; Caulfield Laura E; Herman James G; Guallar Eliseo; Alberg Anthony J
Adulthood consumption of preserved and nonpreserved vegetables and the risk of nasopharyngeal carcinoma: a systematic review.
International journal of cancer. Journal international du cancer 2006;119(5):1125-35.
2006: Guo Mingzhou; Ren Jingli; House Michael G; Qi Yu; Brock Malcolm V; Herman James G
Accumulation of promoter methylation suggests epigenetic progression in squamous cell carcinoma of the esophagus.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(15):4515-22.
2006: Han Weiguo; Cauchi Stephane; Herman James G; Spivack Simon D
DNA methylation mapping by tag-modified bisulfite genomic sequencing.
Analytical biochemistry 2006;355(1):50-61.
2006: Brandes Johann C; Herman James G
p53 expression after treatment with zebularine is not due to demethylation.
Cancer research 2006;66(13):6892; author reply 6893.
2006: Fenton Hubert; Carlile Brian; Montgomery Elizabeth A; Carraway Hetty; Herman James; Sahin Fikret; Su Gloria H; Argani Pedram
LKB1 protein expression in human breast cancer.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2006;14(2):146-53.
2006: Gore Steven D; Baylin Stephen; Sugar Elizabeth; Carraway Hetty; Miller Carole B; Carducci Michael; Grever Michael; Galm Oliver; Dauses Tianna; Karp Judith E; Rudek Michelle A; Zhao Ming; Smith B Douglas; Manning Jasper; Jiemjit Anchalee; Dover George; Mays Abbie; Zwiebel James; Murgo Anthony; Weng Li-Jun; Herman James G
Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms.
Cancer research 2006;66(12):6361-9.
2006: Machida Emi Ota; Brock Malcolm V; Hooker Craig M; Nakayama Jun; Ishida Akiko; Amano Jun; Picchi Maria A; Belinsky Steven A; Herman James G; Taniguchi Shun'ichiro; Baylin Stephen B
Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer.
Cancer research 2006;66(12):6210-8.
2006: Pruitt Kevin; Zinn Rebekah L; Ohm Joyce E; McGarvey Kelly M; Kang Sung-Hae L; Watkins D Neil; Herman James G; Baylin Stephen B
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.
PLoS genetics 2006;2(3):e40.
2006: Belinsky Steven A; Liechty Kieu C; Gentry Frederick D; Wolf Holly J; Rogers Justin; Vu Kieu; Haney Jerry; Kennedy Tim C; Hirsch Fred R; Miller York; Franklin Wilbur A; Herman James G; Baylin Stephen B; Bunn Paul A; Byers Tim
Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort.
Cancer research 2006;66(6):3338-44.
2006: Weaver Kyle D; Grossman Stuart A; Herman James G
Methylated tumor-specific DNA as a plasma biomarker in patients with glioma.
Cancer investigation 2006;24(1):35-40.
2006: Guo Mingzhou; Liu Shuang; Herman James G; Zhuang Hui; Lu Fengmin
Gefitinib-sensitizing mutation in esophageal carcinoma cell line Kyse450.
Cancer biology & therapy 2006;5(2):152-5.
2006: Galm Oliver; Herman James G; Baylin Stephen B
The fundamental role of epigenetics in hematopoietic malignancies.
Blood reviews 2006;20(1):1-13.
2006: Derks Sarah; Postma Cindy; Moerkerk Peter T M; van den Bosch Sandra M; Carvalho Beatriz; Hermsen Mario A J A; Giaretti Walter; Herman James G; Weijenberg Matty P; de Bruïne Adriaan P; Meijer Gerrit A; van Engeland Manon
Promoter methylation precedes chromosomal alterations in colorectal cancer development.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2006;28(5-6):247-57.
2005: Galm Oliver; Wilop Stefan; Lüders Christian; Jost Edgar; Gehbauer Gerald; Herman James G; Osieka Rainhardt
Clinical implications of aberrant DNA methylation patterns in acute myelogenous leukemia.
Annals of hematology 2005;84 Suppl 1():39-46.
2005: Brock Malcolm V; Hooker Craig M; Yung Rex; Guo Mingzhou; Han Yu; Ames Stephen E; Chang David; Yang Stephen C; Mason David; Sussman Marc; Baylin Stephen B; Herman James G
Can we improve the cytologic examination of malignant pleural effusions using molecular analysis?
The Annals of thoracic surgery 2005;80(4):1241-7.
2005: Ting Angela H; Schuebel Kornel E; Herman James G; Baylin Stephen B
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation.
Nature genetics 2005;37(8):906-10.
2005: Galm Oliver; Suzuki Hiromu; Akiyama Yoshimitsu; Esteller Manel; Brock Malcolm V; Osieka Rainhardt; Baylin Stephen B; Herman James G
Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies.
Oncogene 2005;24(30):4799-805.
2005: Brandes Johann C; van Engeland Manon; Wouters Kim A D; Weijenberg Matty P; Herman James G
CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype.
Carcinogenesis 2005;26(6):1152-6.
2005: Hong Kyeong-Man; Yang Sei-Hoon; Guo Mingzhou; Herman James G; Jen Jin
Semiautomatic detection of DNA methylation at CpG islands.
BioTechniques 2005;38(3):354, 356, 358.
2005: Yang Bin; House Michael G; Guo Mingzhou; Herman James G; Clark Douglas P
Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(3):412-20.
2005: Brock Malcolm V; Hooker Craig M; Syphard James E; Westra William; Xu Li; Alberg Anthony J; Mason David; Baylin Stephen B; Herman James G; Yung Rex C; Brahmer Julie; Rudin Charles M; Ettinger David S; Yang Stephen C
Surgical resection of limited disease small cell lung cancer in the new era of platinum chemotherapy: Its time has come.
The Journal of thoracic and cardiovascular surgery 2005;129(1):64-72.
2005: Herman J G
Epigenetic changes in cancer and preneoplasia.
Cold Spring Harbor symposia on quantitative biology 2005;70():329-33.
2005: Galm Oliver; Herman James G
Methylation-specific polymerase chain reaction.
Methods in molecular medicine 2005;113():279-91.
2004: Keen Judith C; Garrett-Mayer Elizabeth; Pettit Catherine; Mack Kelly M; Manning Jasper; Herman James G; Davidson Nancy E
Epigenetic regulation of protein phosphatase 2A (PP2A), lymphotactin (XCL1) and estrogen receptor alpha (ER) expression in human breast cancer cells.
Cancer biology & therapy 2004;3(12):1304-12.
2004: Guo Mingzhou; Akiyama Yoshimitsu; House Michael G; Hooker Craig M; Heath Elizabeth; Gabrielson Edward; Yang Stephen C; Han Yu; Baylin Stephen B; Herman James G; Brock Malcolm V
Hypermethylation of the GATA genes in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):7917-24.
2004: Galm O; Wilop S; Reichelt J; Jost E; Gehbauer G; Herman J G; Osieka R
DNA methylation changes in multiple myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2004;18(10):1687-92.
2004: Bae Young Kyung; Brown Amy; Garrett Elizabeth; Bornman Daniel; Fackler Mary Jo; Sukumar Saraswati; Herman James G; Gabrielson Edward
Hypermethylation in histologically distinct classes of breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 1):5998-6005.
2004: Ibanez de Caceres Inmaculada; Battagli Cristina; Esteller Manel; Herman James G; Dulaimi Essel; Edelson Mitchell I; Bergman Cynthia; Ehya Hormoz; Eisenberg Burton L; Cairns Paul
Tumor cell-specific BRCA1 and RASSF1A hypermethylation in serum, plasma, and peritoneal fluid from ovarian cancer patients.
Cancer research 2004;64(18):6476-81.
2004: Guo Mingzhou; House Michael G; Hooker Craig; Han Yu; Heath Elizabeth; Gabrielson Edward; Yang Stephen C; Baylin Stephen B; Herman James G; Brock Malcolm V
Promoter hypermethylation of resected bronchial margins: a field defect of changes?
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5131-6.
2004: Gilbert Jill; Gore Steve D; Herman James G; Carducci Michael A
The clinical application of targeting cancer through histone acetylation and hypomethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4589-96.
2004: Herman James G
Circulating methylated DNA.
Annals of the New York Academy of Sciences 2004;1022():33-9.
2004: Herman James G
Epigenetics in lung cancer: focus on progression and early lesions.
Chest 2004;125(5 Suppl):119S-22S.
2004: Suzuki Hiromu; Watkins D Neil; Jair Kam-Wing; Schuebel Kornel E; Markowitz Sanford D; Chen Wei Dong; Pretlow Theresa P; Yang Bin; Akiyama Yoshimitsu; Van Engeland Manon; Toyota Minoru; Tokino Takashi; Hinoda Yuji; Imai Kohzoh; Herman James G; Baylin Stephen B
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.
Nature genetics 2004;36(4):417-22.
2004: Musulén Eva; Moreno Víctor; Reyes German; Sancho Francisco Javier; Peinado Miguel Angel; Esteller Manel; Herman James G; Combalia Neus; Rey Mercè; Capellá Gabriel
Standardized approach for microsatellite instability detection in gastric carcinomas.
Human pathology 2004;35(3):335-42.
2004: Douglas Donna B; Akiyama Yoshimitsu; Carraway Hetty; Belinsky Steven A; Esteller Manel; Gabrielson Edward; Weitzman Sigmund; Williams Trevor; Herman James G; Baylin Stephen B
Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer.
Cancer research 2004;64(5):1611-20.
2004: Esteller Manel; Herman James G
Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer.
Oncogene 2004;23(1):1-8.
2004: Derks Sarah; Lentjes Marjolein H F M; Hellebrekers Debby M E I; de Bruïne Adriaan P; Herman James G; van Engeland Manon
Methylation-specific PCR unraveled.
Cellular oncology : the official journal of the International Society for Cellular Oncology 2004;26(5-6):291-9.
2003: House Michael G; Guo MingZhou; Efron David T; Lillemoe Keith D; Cameron John L; Syphard James E; Hooker Craig M; Abraham Susan C; Montgomery Elizabeth A; Herman James G; Brock Malcolm V
Tumor suppressor gene hypermethylation as a predictor of gastric stromal tumor behavior.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2003;7(8):1004-14; discussion 1014.
2003: House Michael G; Herman James G; Guo Ming Zhou; Hooker Craig M; Schulick Richard D; Cameron John L; Hruban Ralph H; Maitra Anirban; Yeo Charles J
Prognostic value of hMLH1 methylation and microsatellite instability in pancreatic endocrine neoplasms.
Surgery 2003;134(6):902-8; discussion 909.
2003: Akiyama Yoshimitsu; Watkins Neil; Suzuki Hiromu; Jair Kam-Wing; van Engeland Manon; Esteller Manel; Sakai Hidekazu; Ren Chun-Yan; Yuasa Yasuhito; Herman James G; Baylin Stephen B
GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer.
Molecular and cellular biology 2003;23(23):8429-39.
2003: Herman James G; Baylin Stephen B
Gene silencing in cancer in association with promoter hypermethylation.
The New England journal of medicine 2003;349(21):2042-54.
2003: Belinsky Steven A; Klinge Donna M; Stidley Christine A; Issa Jean-Pierre; Herman James G; March Thomas H; Baylin Stephen B
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Cancer research 2003;63(21):7089-93.
2003: Corn Paul G; McDonald E Robert; Herman James G; El-Deiry Wafik S
Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
Nature genetics 2003;35(3):229-37.
2003: van Noesel Max M; van Bezouw Saskia; Voûte P A; Herman James G; Pieters Rob; Versteeg Rogier
Clustering of hypermethylated genes in neuroblastoma.
Genes, chromosomes & cancer 2003;38(3):226-33.
2003: House Michael G; Wistuba Ignacio I; Argani Pedram; Guo MingZhou; Schulick Richard D; Hruban Ralph H; Herman James G; Maitra Anirban
Progression of gene hypermethylation in gallstone disease leading to gallbladder cancer.
Annals of surgical oncology 2003;10(8):882-9.
2003: Yan Lan; Nass Sharyl J; Smith Dawn; Nelson William G; Herman James G; Davidson Nancy E
Specific inhibition of DNMT1 by antisense oligonucleotides induces re-expression of estrogen receptor-alpha (ER) in ER-negative human breast cancer cell lines.
Cancer biology & therapy 2003;2(5):552-6.
2003: Tarafa Gemma; Prat Esther; Risques Rosa-Ana; González Sara; Camps Jordi; Grau Mónica; Guinó Elisabeth; Moreno Víctor; Esteller Manel; Herman James G; Germà Josep-Ramon; Miró Rosa; Peinado Miguel Angel; Capellá Gabriel
Common genetic evolutionary pathways in familial adenomatous polyposis tumors.
Cancer research 2003;63(18):5731-7.
2003: House Michael G; Herman James G; Guo Ming Zhou; Hooker Craig M; Schulick Richard D; Lillemoe Keith D; Cameron John L; Hruban Ralph H; Maitra Anirban; Yeo Charles J
Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms.
Annals of surgery 2003;238(3):423-31; discussion 431-2.
2003: Yang Bin; Guo Mingzhou; Herman James G; Clark Douglas P
Aberrant promoter methylation profiles of tumor suppressor genes in hepatocellular carcinoma.
The American journal of pathology 2003;163(3):1101-7.
2003: Brock Malcolm V; Gou Mingzhou; Akiyama Yoshimitsu; Muller Alison; Wu Tsung-Teh; Montgomery Elizabeth; Deasel Mari; Germonpré Paul; Rubinson Lewis; Heitmiller Richard F; Yang Stephen C; Forastiere Arlene A; Baylin Stephen B; Herman James G
Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2912-9.
2003: Sarrió David; Moreno-Bueno Gema; Hardisson David; Sánchez-Estévez Carolina; Guo Mingzhou; Herman James G; Gamallo Carlos; Esteller Manel; Palacios José
Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability.
International journal of cancer. Journal international du cancer 2003;106(2):208-15.
2003: van Engeland Manon; Weijenberg Matty P; Roemen Guido M J M; Brink Mirian; de Bruïne Adriaan P; Goldbohm R Alexandra; van den Brandt Piet A; Baylin Stephen B; de Goeij Anton F P M; Herman James G
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Cancer research 2003;63(12):3133-7.
2003: Holst Charles R; Nuovo Gerard J; Esteller Manel; Chew Karen; Baylin Stephen B; Herman James G; Tlsty Thea D
Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.
Cancer research 2003;63(7):1596-601.
2003: Moreno-Bueno Gema; Hardisson David; Sarrió David; Sánchez Carolina; Cassia Raúl; Prat Jaime; Herman James G; Esteller Manel; Matías-Guiu Xavier; Palacios José
Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia.
The Journal of pathology 2003;199(4):471-8.
2003: Galm Oliver; Yoshikawa Hirohide; Esteller Manel; Osieka Rainhardt; Herman James G
SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma.
Blood 2003;101(7):2784-8.
2003: Paz Maria F; Fraga Mario F; Avila Sonia; Guo Mingzhou; Pollan Marina; Herman James G; Esteller Manel
A systematic profile of DNA methylation in human cancer cell lines.
Cancer research 2003;63(5):1114-21.
2003: House Michael G; Guo MingZhou; Iacobuzio-Donahue Christine; Herman James G
Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas.
Carcinogenesis 2003;24(2):193-8.
2003: Chen Wen Yong; Zeng Xiaobei; Carter Mark G; Morrell Craig N; Chiu Yen Ray-Whay; Esteller Manel; Watkins D Neil; Herman James G; Mankowski Joseph L; Baylin Stephen B
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.
Nature genetics 2003;33(2):197-202.
2003: Bachman Kurtis E; Park Ben Ho; Rhee Ina; Rajagopalan Harith; Herman James G; Baylin Stephen B; Kinzler Kenneth W; Vogelstein Bert
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.
Cancer cell 2003;3(1):89-95.
2002: Fahrner Jill A; Eguchi Sayaka; Herman James G; Baylin Stephen B
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.
Cancer research 2002;62(24):7213-8.
2002: Herman James G
Hypermethylation pathways to colorectal cancer. Implications for prevention and detection.
Gastroenterology clinics of North America 2002;31(4):945-58.
2002: Tort Frederic; Hernàndez Silvia; Beà Silvia; Martínez Antonio; Esteller Manel; Herman James G; Puig Xavier; Camacho Emma; Sánchez Montse; Nayach Iracema; Lopez-Guillermo Armando; Fernández Pedro L; Colomer Dolors; Hernàndez Luis; Campo Elias
CHK2-decreased protein expression and infrequent genetic alterations mainly occur in aggressive types of non-Hodgkin lymphomas.
Blood 2002;100(13):4602-8.
2002: Lerma Enrique; Esteller Manel; Herman James G; Prat Jaime
Alterations of the p16/Rb/cyclin-D1 pathway in vulvar carcinoma, vulvar intraepithelial neoplasia, and lichen sclerosus.
Human pathology 2002;33(11):1120-5.
2002: Moreno-Bueno Gema; Hardisson David; Sánchez Carolina; Sarrió David; Cassia Raúl; García-Rostán Ginesa; Prat Jaime; Guo Mingzhou; Herman James G; Matías-Guiu Xavier; Esteller Manel; Palacios José
Abnormalities of the APC/beta-catenin pathway in endometrial cancer.
Oncogene 2002;21(52):7981-90.
2002: Esteller Manel; Guo Mingzhou; Moreno Victor; Peinado Miquel Angel; Capella Gabriel; Galm Oliver; Baylin Stephen B; Herman James G
Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer.
Cancer research 2002;62(20):5902-5.
2002: Cameron Elizabeth; Mijovic Aleksandar; Herman James G; Baylin Stephen B; Pradhan Anjala; Mufti Ghulam J; Rassool Feyruz V
P15INK4B is not mutated in adult familial myelodysplastic syndromes.
British journal of haematology 2002;119(1):277-9.
2002: Esteller Manel; Fraga Mario F; Paz Maria F; Campo Elias; Colomer Dolors; Novo Francisco J; Calasanz Maria J; Galm Oliver; Guo Mingzhou; Benitez Javier; Herman James G
Cancer epigenetics and methylation.
Science (New York, N.Y.) 2002;297(5588):1807-8; discussion 1807-8.
2002: Paz Maria F; Avila Sonia; Fraga Mario F; Pollan Marina; Capella Gabriel; Peinado Miquel Angel; Sanchez-Cespedes Montserrat; Herman James G; Esteller Manel
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.
Cancer research 2002;62(15):4519-24.
2002: Sanchez-Cespedes Montserrat; Parrella Paola; Esteller Manel; Nomoto Shuji; Trink Barry; Engles James M; Westra William H; Herman James G; Sidransky David
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.
Cancer research 2002;62(13):3659-62.
2002: Suzuki Hiromu; Gabrielson Edward; Chen Wei; Anbazhagan Ramaswamy; van Engeland Manon; Weijenberg Matty P; Herman James G; Baylin Stephen B
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.
Nature genetics 2002;31(2):141-9.
2002: van Engeland Manon; Roemen Guido M J M; Brink Mirian; Pachen Marco M M; Weijenberg Matty P; de Bruïne Adriaan P; Arends Jan-Willem; van den Brandt Piet A; de Goeij Anton F P M; Herman James G
K-ras mutations and RASSF1A promoter methylation in colorectal cancer.
Oncogene 2002;21(23):3792-5.
2002: van Noesel Max M; van Bezouw Saskia; Salomons Gajja S; Voûte P A; Pieters Rob; Baylin Steve B; Herman James G; Versteeg Rogier
Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation.
Cancer research 2002;62(7):2157-61.
2002: Laiho Päivi; Launonen Virpi; Lahermo Päivi; Esteller Manel; Guo Mingzhou; Herman James G; Mecklin Jukka-Pekka; Järvinen Heikki; Sistonen Pertti; Kim Kyoung-Mee; Shibata Darryl; Houlston Richard S; Aaltonen Lauri A
Low-level microsatellite instability in most colorectal carcinomas.
Cancer research 2002;62(4):1166-70.
2002: Galm Oliver; Rountree Michael R; Bachman Kurtis E; Jair Kam-Wing; Baylin Stephen B; Herman James G
Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density.
Genome research 2002;12(1):153-7.
2002: Esteller Manel; Gaidano Gianluca; Goodman Steven N; Zagonel Vittorina; Capello Daniela; Botto Barbara; Rossi Davide; Gloghini Annunziata; Vitolo Umberto; Carbone Antonino; Baylin Stephen B; Herman James G
Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma.
Journal of the National Cancer Institute 2002;94(1):26-32.
2002: Esteller Manel; Herman James G
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours.
The Journal of pathology 2002;196(1):1-7.
2001: Esteller M; Fraga M F; Guo M; Garcia-Foncillas J; Hedenfalk I; Godwin A K; Trojan J; Vaurs-Barrière C; Bignon Y J; Ramus S; Benitez J; Caldes T; Akiyama Y; Yuasa Y; Launonen V; Canal M J; Rodriguez R; Capella G; Peinado M A; Borg A; Aaltonen L A; Ponder B A; Baylin S B; Herman J G
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Human molecular genetics 2001;10(26):3001-7.
2001: Yang X; Phillips D L; Ferguson A T; Nelson W G; Herman J G; Davidson N E
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells.
Cancer research 2001;61(19):7025-9.
2001: Caballero O L; Cohen D; Liu Q; Esteller M; Bonacum J; White P; Engles J; Yochem R; Herman J G; Westra W H; Lengauer C; Sidransky D; Jen J
Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer.
Genes, chromosomes & cancer 2001;32(2):119-25.
2001: Corn P G; Heath E I; Heitmiller R; Fogt F; Forastiere A A; Herman J G; Wu T T
Frequent hypermethylation of the 5' CpG island of E-cadherin in esophageal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2765-9.
2001: Cairns P; Esteller M; Herman J G; Schoenberg M; Jeronimo C; Sanchez-Cespedes M; Chow N H; Grasso M; Wu L; Westra W B; Sidransky D
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2727-30.
2001: Bornman D M; Mathew S; Alsruhe J; Herman J G; Gabrielson E
Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals.
The American journal of pathology 2001;159(3):831-5.
2001: Nicholson S A; Okby N T; Khan M A; Welsh J A; McMenamin M G; Travis W D; Jett J R; Tazelaar H D; Trastek V; Pairolero P C; Corn P G; Herman J G; Liotta L A; Caporaso N E; Harris C C
Alterations of p14ARF, p53, and p73 genes involved in the E2F-1-mediated apoptotic pathways in non-small cell lung carcinoma.
Cancer research 2001;61(14):5636-43.
2001: Virmani A K; Rathi A; Sathyanarayana U G; Padar A; Huang C X; Cunnigham H T; Farinas A J; Milchgrub S; Euhus D M; Gilcrease M; Herman J; Minna J D; Gazdar A F
Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1998-2004.
2001: Esteller M; Risques R A; Toyota M; Capella G; Moreno V; Peinado M A; Baylin S B; Herman J G
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
Cancer research 2001;61(12):4689-92.
2001: Herman J G; Baylin S B
Methylation-specific PCR.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 10():Unit 10.6.
2001: Rountree M R; Bachman K E; Herman J G; Baylin S B
DNA methylation, chromatin inheritance, and cancer.
Oncogene 2001;20(24):3156-65.
2001: Baylin S B; Herman J G
Promoter hypermethylation--can this change alone ever designate true tumor suppressor gene function?
Journal of the National Cancer Institute 2001;93(9):664-5.
2001: Yoshikawa H; Matsubara K; Qian G S; Jackson P; Groopman J D; Manning J E; Harris C C; Herman J G
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity.
Nature genetics 2001;28(1):29-35.
2001: Esteller M; Corn P G; Baylin S B; Herman J G
A gene hypermethylation profile of human cancer.
Cancer research 2001;61(8):3225-9.
2001: Esteller M; Cordon-Cardo C; Corn P G; Meltzer S J; Pohar K S; Watkins D N; Capella G; Peinado M A; Matias-Guiu X; Prat J; Baylin S B; Herman J G
p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Cancer research 2001;61(7):2816-21.
2001: Baylin S B; Esteller M; Rountree M R; Bachman K E; Schuebel K; Herman J G
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer.
Human molecular genetics 2001;10(7):687-92.
2001: Sanchez-Cespedes M; Decker P A; Doffek K M; Esteller M; Westra W H; Alawi E A; Herman J G; Demeure M J; Sidransky D; Ahrendt S A
Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers.
Cancer research 2001;61(5):2092-6.
2001: Esteller M; González S; Risques R A; Marcuello E; Mangues R; Germà J R; Herman J G; Capellà G; Peinado M A
K-ras and p16 aberrations confer poor prognosis in human colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(2):299-304.
2001: Soengas M S; Capodieci P; Polsky D; Mora J; Esteller M; Opitz-Araya X; McCombie R; Herman J G; Gerald W L; Lazebnik Y A; Cordón-Cardó C; Lowe S W
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma.
Nature 2001;409(6817):207-11.
2001: Anbazhagan R; Herman J G; Enika K; Gabrielson E
Spreadsheet-based program for the analysis of DNA methylation.
BioTechniques 2001;30(1):110-4.
2000: Yang X; Ferguson A T; Nass S J; Phillips D L; Butash K A; Wang S M; Herman J G; Davidson N E
Transcriptional activation of estrogen receptor alpha in human breast cancer cells by histone deacetylase inhibition.
Cancer research 2000;60(24):6890-4.
2000: Corn P G; Smith B D; Ruckdeschel E S; Douglas D; Baylin S B; Herman J G
E-cadherin expression is silenced by 5' CpG island methylation in acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4243-8.
2000: Esteller M; Garcia-Foncillas J; Andion E; Goodman S N; Hidalgo O F; Vanaclocha V; Baylin S B; Herman J G
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
The New England journal of medicine 2000;343(19):1350-4.
2000: Baylin S B; Belinsky S A; Herman J G
Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promise.
Journal of the National Cancer Institute 2000;92(18):1460-1.
2000: Esteller M; Sparks A; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Gonzalez S; Tarafa G; Sidransky D; Meltzer S J; Baylin S B; Herman J G
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.
Cancer research 2000;60(16):4366-71.
2000: Nass S J; Herman J G; Gabrielson E; Iversen P W; Parl F F; Davidson N E; Graff J R
Aberrant methylation of the estrogen receptor and E-cadherin 5' CpG islands increases with malignant progression in human breast cancer.
Cancer research 2000;60(16):4346-8.
2000: Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Watkins D N; Issa J P; Sidransky D; Baylin S B; Herman J G
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Cancer research 2000;60(9):2368-71.
2000: Rhee I; Jair K W; Yen R W; Lengauer C; Herman J G; Kinzler K W; Vogelstein B; Baylin S B; Schuebel K E
CpG methylation is maintained in human cancer cells lacking DNMT1.
Nature 2000;404(6781):1003-7.
2000: Esteller M; Silva J M; Dominguez G; Bonilla F; Matias-Guiu X; Lerma E; Bussaglia E; Prat J; Harkes I C; Repasky E A; Gabrielson E; Schutte M; Baylin S B; Herman J G
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
Journal of the National Cancer Institute 2000;92(7):564-9.
2000: Baylin S B; Herman J G
DNA hypermethylation in tumorigenesis: epigenetics joins genetics.
Trends in genetics : TIG 2000;16(4):168-74.
2000: Sanchez-Cespedes M; Esteller M; Wu L; Nawroz-Danish H; Yoo G H; Koch W M; Jen J; Herman J G; Sidransky D
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients.
Cancer research 2000;60(4):892-5.
2000: Eng C; Herman J G; Baylin S B
A bird's eye view of global methylation.
Nature genetics 2000;24(2):101-2.
2000: Esteller M; Tortola S; Toyota M; Capella G; Peinado M A; Baylin S B; Herman J G
Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.
Cancer research 2000;60(1):129-33.
2000: Esteller M; Avizienyte E; Corn P G; Lothe R A; Baylin S B; Aaltonen L A; Herman J G
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome.
Oncogene 2000;19(1):164-8.
2000: Graff J R; Gabrielson E; Fujii H; Baylin S B; Herman J G
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression.
The Journal of biological chemistry 2000;275(4):2727-32.
2000: Herman J G; Baylin S B
Promoter-region hypermethylation and gene silencing in human cancer.
Current topics in microbiology and immunology 2000;249():35-54.
1999: Esteller M; Catasus L; Matias-Guiu X; Mutter G L; Prat J; Baylin S B; Herman J G
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis.
The American journal of pathology 1999;155(5):1767-72.
1999: Sanchez-Cespedes M; Reed A L; Buta M; Wu L; Westra W H; Herman J G; Yang S C; Jen J; Sidransky D
Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer.
Oncogene 1999;18(43):5843-9.
1999: Herman J G
Hypermethylation of tumor suppressor genes in cancer.
Seminars in cancer biology 1999;9(5):359-67.
1999: Nuovo G J; Plaia T W; Belinsky S A; Baylin S B; Herman J G
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12754-9.
1999: Cameron E E; Baylin S B; Herman J G
p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing.
Blood 1999;94(7):2445-51.
1999: Sanchez-Cespedes M; Esteller M; Hibi K; Cope F O; Westra W H; Piantadosi S; Herman J G; Jen J; Sidransky D
Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2450-4.
1999: Zhu J J; Maruyama T; Jacoby L B; Herman J G; Gusella J F; Black P M; Wu J K
Clonal analysis of a case of multiple meningiomas using multiple molecular genetic approaches: pathology case report.
Neurosurgery 1999;45(2):409-16.
1999: Corn P G; Kuerbitz S J; van Noesel M M; Esteller M; Compitello N; Baylin S B; Herman J G
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation.
Cancer research 1999;59(14):3352-6.
1999: Toyota M; Ahuja N; Ohe-Toyota M; Herman J G; Baylin S B; Issa J P
CpG island methylator phenotype in colorectal cancer.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8681-6.
1999: Katzenellenbogen R A; Baylin S B; Herman J G
Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies.
Blood 1999;93(12):4347-53.
1999: Ahrendt S A; Chow J T; Xu L H; Yang S C; Eisenberger C F; Esteller M; Herman J G; Wu L; Decker P A; Jen J; Sidransky D
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.
Journal of the National Cancer Institute 1999;91(4):332-9.
1999: Bachman K E; Herman J G; Corn P G; Merlo A; Costello J F; Cavenee W K; Baylin S B; Graff J R
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.
Cancer research 1999;59(4):798-802.
1999: Esteller M; Hamilton S R; Burger P C; Baylin S B; Herman J G
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
Cancer research 1999;59(4):793-7.
1999: Herman J G
p16(INK4): involvement early and often in gastrointestinal malignancies.
Gastroenterology 1999;116(2):483-5.
1999: Cameron E E; Bachman K E; Myöhänen S; Herman J G; Baylin S B
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer.
Nature genetics 1999;21(1):103-7.
1999: Esteller M; Sanchez-Cespedes M; Rosell R; Sidransky D; Baylin S B; Herman J G
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.
Cancer research 1999;59(1):67-70.
1998: Jarrard D F; Kinoshita H; Shi Y; Sandefur C; Hoff D; Meisner L F; Chang C; Herman J G; Isaacs W B; Nassif N
Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells.
Cancer research 1998;58(23):5310-4.
1998: Esteller M; Levine R; Baylin S B; Ellenson L H; Herman J G
MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.
Oncogene 1998;17(18):2413-7.
1998: Esteller M; Corn P G; Urena J M; Gabrielson E; Baylin S B; Herman J G
Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia.
Cancer research 1998;58(20):4515-8.
1998: Cairns P; Evron E; Okami K; Halachmi N; Esteller M; Herman J G; Bose S; Wang S I; Parsons R; Sidransky D
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers.
Oncogene 1998;16(24):3215-8.
1998: Lapidus R G; Nass S J; Butash K A; Parl F F; Weitzman S A; Graff J G; Herman J G; Davidson N E
Mapping of ER gene CpG island methylation-specific polymerase chain reaction.
Cancer research 1998;58(12):2515-9.
1998: Herman J G; Umar A; Polyak K; Graff J R; Ahuja N; Issa J P; Markowitz S; Willson J K; Hamilton S R; Kinzler K W; Kane M F; Kolodner R D; Vogelstein B; Kunkel T A; Baylin S B
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6870-5.
1998: Graff J R; Greenberg V E; Herman J G; Westra W H; Boghaert E R; Ain K B; Saji M; Zeiger M A; Zimmer S G; Baylin S B
Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma.
Cancer research 1998;58(10):2063-6.
1998: Hiraguri S; Godfrey T; Nakamura H; Graff J; Collins C; Shayesteh L; Doggett N; Johnson K; Wheelock M; Herman J; Baylin S; Pinkel D; Gray J
Mechanisms of inactivation of E-cadherin in breast cancer cell lines.
Cancer research 1998;58(9):1972-7.
1998: Myöhänen S K; Baylin S B; Herman J G
Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia.
Cancer research 1998;58(4):591-3.
1998: Muscarella P; Melvin W S; Fisher W E; Foor J; Ellison E C; Herman J G; Schirmer W J; Hitchcock C L; DeYoung B R; Weghorst C M
Genetic alterations in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors: an analysis of p16/MTS1 tumor suppressor gene inactivation.
Cancer research 1998;58(2):237-40.
1998: Baylin S B; Herman J G; Graff J R; Vertino P M; Issa J P
Alterations in DNA methylation: a fundamental aspect of neoplasia.
Advances in cancer research 1998;72():141-96.
1997: Cairns P; Okami K; Halachmi S; Halachmi N; Esteller M; Herman J G; Jen J; Isaacs W B; Bova G S; Sidransky D
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
Cancer research 1997;57(22):4997-5000.
1997: Ahuja N; Mohan A L; Li Q; Stolker J M; Herman J G; Hamilton S R; Baylin S B; Issa J P
Association between CpG island methylation and microsatellite instability in colorectal cancer.
Cancer research 1997;57(16):3370-4.
1997: Graff J R; Herman J G; Myöhänen S; Baylin S B; Vertino P M
Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.
The Journal of biological chemistry 1997;272(35):22322-9.
1997: Schutte M; Hruban R H; Geradts J; Maynard R; Hilgers W; Rabindran S K; Moskaluk C A; Hahn S A; Schwarte-Waldhoff I; Schmiegel W; Baylin S B; Kern S E; Herman J G
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.
Cancer research 1997;57(15):3126-30.
1997: Jarrard D F; Bova G S; Ewing C M; Pin S S; Nguyen S H; Baylin S B; Cairns P; Sidransky D; Herman J G; Isaacs W B
Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer.
Genes, chromosomes & cancer 1997;19(2):90-6.
1997: Kubota T; Das S; Christian S L; Baylin S B; Herman J G; Ledbetter D H
Methylation-specific PCR simplifies imprinting analysis.
Nature genetics 1997;16(1):16-7.
1997: Issa J P; Baylin S B; Herman J G
DNA methylation changes in hematologic malignancies: biologic and clinical implications.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 1():S7-11.
1997: Herman J G; Civin C I; Issa J P; Collector M I; Sharkis S J; Baylin S B
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies.
Cancer research 1997;57(5):837-41.
1996: Herman J G; Graff J R; Myöhänen S; Nelkin B D; Baylin S B
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9821-6.
1996: Herman J G; Jen J; Merlo A; Baylin S B
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.
Cancer research 1996;56(4):722-7.
1996: Wu J; Herman J G; Wilson G; Lee R Y; Yen R W; Mabry M; de Bustros A; Nelkin B D; Baylin S B
Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.
Cancer research 1996;56(3):616-22.
1995: Graff J R; Herman J G; Lapidus R G; Chopra H; Xu R; Jarrard D F; Isaacs W B; Pitha P M; Davidson N E; Baylin S B
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.
Cancer research 1995;55(22):5195-9.
1995: Herman J G; Merlo A; Mao L; Lapidus R G; Issa J P; Davidson N E; Sidransky D; Baylin S B
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.
Cancer research 1995;55(20):4525-30.
1995: Merlo A; Herman J G; Mao L; Lee D J; Gabrielson E; Burger P C; Baylin S B; Sidransky D
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Nature medicine 1995;1(7):686-92.
1994: Herman J G; Latif F; Weng Y; Lerman M I; Zbar B; Liu S; Samid D; Duan D S; Gnarra J R; Linehan W M
Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9700-4.
1993: Wu J; Issa J P; Herman J; Bassett D E; Nelkin B D; Baylin S B
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8891-5.
1989: Nelkin B D; Nakamura Y; White R W; de Bustros A C; Herman J; Wells S A; Baylin S B
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
Cancer research 1989;49(15):4114-9.
1988: Herman J G; Beschorner W E; Baughman K L; Boitnott J K; Vogelsang G B; Baumgartner W A
Pseudo-graft-versus-host disease in heart and heart-lung recipients.
Transplantation 1988;46(1):93-8.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

James Herman

Research Profile (preview)

Physiology

Chemicals & Drugs

Genes & Molecular Sequences

Procedures

Anatomy

Disorders

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of James Herman (preview)

All Publications